spacer

GO:0004722 protein serine/threonine phosphatase activity

Term Information

ID GO:0004722
Name protein serine/threonine phosphatase activity
Ontology Molecular Function
Definition Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
Secondary IDs GO:0000158 GO:0000163 GO:0008598 GO:0008600 GO:0015071 GO:0030357 GO:0030358 GO:0030360 GO:0030361
GONUTS GO:0004722 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow protein phosphatase X
narrow protein phosphatase type 1 activity
exact serine/threonine specific protein phosphatase activity
narrow calcineurin
narrow protein phosphatase type 4, intrinsic catalyst activity
narrow protein phosphatase type 4 activity
narrow protein phosphatase type 2C activity
narrow protein phosphatase type 2B, intrinsic catalyst activity
narrow protein phosphatase type 2B activity
narrow protein phosphatase type 2A, intrinsic catalyst activity
narrow protein phosphatase type 1, intrinsic catalyst activity
narrow protein phosphatase type 2A activity
narrow protein D phosphatase
narrow polycation modulated (PCM-) phosphatase
narrow phosphospectrin phosphatase
narrow phosphopyruvate dehydrogenase phosphatase
narrow phosphatase SP
narrow phosphatase IV
narrow phosphatase III
narrow phosphatase II
narrow phosphatase IB
narrow phosphatase I
narrow phosphatase H-II
narrow phosphatase C-II
narrow phosphatase 2B
narrow phosphatase 2A
narrow casein phosphatase
narrow branched-chain alpha-keto acid dehydrogenase phosphatase
narrow HMG-CoA reductase phosphatase
narrow 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase
narrow Aspergillus awamori acid protein phosphatase
narrow BCKDH phosphatase

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR000222

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004722:
Relationship To GO:0004722 Child Term Child Term Name
Is a GO:0009400 receptor signaling protein serine/threonine phosphatase activity
Is a GO:0004723 calcium-dependent protein serine/threonine phosphatase activity
Is a GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity
Is a GO:0008420 CTD phosphatase activity
Regulates GO:0080163 regulation of protein serine/threonine phosphatase activity
Is a GO:0017018 myosin phosphatase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0004722. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0004722 based on the entire annotation set Co-occurrence statistics for GO:0004722 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-08 Deleted XREF MetaCyc:3.1.3.16-RXN
2010-09-24 Added DEFINITION Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2009-05-21 Added XREF MetaCyc:3.1.3.16-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2008-04-01 Updated RELATION is a GO:0004721 (phosphoprotein phosphatase activity)
2008-02-14 Added SECONDARY GO:0030361 (protein phosphatase type 4, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0030358 (protein phosphatase type 2B, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0030357 (protein phosphatase type 2B activity)
2008-02-14 Added SECONDARY GO:0015071 (protein phosphatase type 2C activity)
2008-02-14 Added SECONDARY GO:0008600 (protein phosphatase type 2A, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0008598 (protein phosphatase type 1, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0000163 (protein phosphatase type 1 activity)
2008-02-14 Added SECONDARY GO:0000158 (protein phosphatase type 2A activity)
2008-02-14 Added SYNONYM calcineurin
2008-02-14 Added SYNONYM protein phosphatase X
2008-02-14 Added SYNONYM protein phosphatase type 1 activity
2008-02-14 Added SYNONYM protein phosphatase type 1, intrinsic catalyst activity
2008-02-14 Added SYNONYM protein phosphatase type 2A activity
2008-02-14 Added SYNONYM protein phosphatase type 2A, intrinsic catalyst activity
2008-02-14 Added SYNONYM protein phosphatase type 2B activity
2008-02-14 Added SYNONYM protein phosphatase type 2B, intrinsic catalyst activity
2008-02-14 Added SYNONYM protein phosphatase type 2C activity
2008-02-14 Added SYNONYM protein phosphatase type 4 activity
2008-02-14 Added SYNONYM protein phosphatase type 4, intrinsic catalyst activity
2008-02-14 Added SECONDARY GO:0030360 (protein phosphatase type 4 activity)
2007-12-14 Added SYNONYM branched-chain alpha-keto acid dehydrogenase phosphatase
2007-12-14 Added SYNONYM casein phosphatase
2007-12-14 Added SYNONYM phosphatase 2A
2007-12-14 Added SYNONYM phosphatase 2B
2007-12-14 Added SYNONYM phosphatase C-II
2007-12-14 Added SYNONYM phosphatase H-II
2007-12-14 Added SYNONYM phosphatase I
2007-12-14 Added SYNONYM phosphatase IB
2007-12-14 Added SYNONYM phosphatase II
2007-12-14 Added SYNONYM phosphatase III
2007-12-14 Added SYNONYM phosphatase IV
2007-12-14 Added SYNONYM phosphatase SP
2007-12-14 Added SYNONYM phosphopyruvate dehydrogenase phosphatase
2007-12-14 Added SYNONYM phosphospectrin phosphatase
2007-12-14 Added SYNONYM polycation modulated (PCM-) phosphatase
2007-12-14 Added SYNONYM protein D phosphatase
2007-12-14 Added SYNONYM 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase
2007-12-14 Added SYNONYM Aspergillus awamori acid protein phosphatase
2007-12-14 Added SYNONYM BCKDH phosphatase
2007-12-14 Added SYNONYM HMG-CoA reductase phosphatase
2007-09-06 Added SYNONYM serine/threonine specific protein phosphatase activity
2004-03-03 Updated DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2003-11-05 Deleted XREF MetaCyc:3.1.3.16-RXN
2003-11-05 Deleted XREF EC:3.1.3.16
2003-10-27 Added XREF MetaCyc:3.1.3.16-RXN
2003-03-19 Updated TERM protein serine/threonine phosphatase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.
2002-02-06 Updated TERM protein serine/threonine phosphatase
2001-04-03 Updated TERM protein serine/threonine phosphatase
2001-03-30 Added XREF EC:3.1.3.16
2001-03-30 Added TERM protein serine/threonine phosphatase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM protein serine/threonine phosphatase activity
2002-02-06 Updated TERM protein serine/threonine phosphatase
2001-04-03 Updated TERM protein serine/threonine phosphatase
2001-03-30 Added TERM protein serine/threonine phosphatase

Definition/synonyms

Timestamp Action Category Detail
2010-09-24 Added DEFINITION Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
2010-09-24 Deleted DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2008-05-13 Added DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2008-02-14 Added SYNONYM calcineurin
2008-02-14 Added SYNONYM protein phosphatase X
2008-02-14 Added SYNONYM protein phosphatase type 1 activity
2008-02-14 Added SYNONYM protein phosphatase type 1, intrinsic catalyst activity
2008-02-14 Added SYNONYM protein phosphatase type 2A activity
2008-02-14 Added SYNONYM protein phosphatase type 2A, intrinsic catalyst activity
2008-02-14 Added SYNONYM protein phosphatase type 2B activity
2008-02-14 Added SYNONYM protein phosphatase type 2B, intrinsic catalyst activity
2008-02-14 Added SYNONYM protein phosphatase type 2C activity
2008-02-14 Added SYNONYM protein phosphatase type 4 activity
2008-02-14 Added SYNONYM protein phosphatase type 4, intrinsic catalyst activity
2007-12-14 Added SYNONYM branched-chain alpha-keto acid dehydrogenase phosphatase
2007-12-14 Added SYNONYM casein phosphatase
2007-12-14 Added SYNONYM phosphatase 2A
2007-12-14 Added SYNONYM phosphatase 2B
2007-12-14 Added SYNONYM phosphatase C-II
2007-12-14 Added SYNONYM phosphatase H-II
2007-12-14 Added SYNONYM phosphatase I
2007-12-14 Added SYNONYM phosphatase IB
2007-12-14 Added SYNONYM phosphatase II
2007-12-14 Added SYNONYM phosphatase III
2007-12-14 Added SYNONYM phosphatase IV
2007-12-14 Added SYNONYM phosphatase SP
2007-12-14 Added SYNONYM phosphopyruvate dehydrogenase phosphatase
2007-12-14 Added SYNONYM phosphospectrin phosphatase
2007-12-14 Added SYNONYM polycation modulated (PCM-) phosphatase
2007-12-14 Added SYNONYM protein D phosphatase
2007-12-14 Added SYNONYM 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase
2007-12-14 Added SYNONYM Aspergillus awamori acid protein phosphatase
2007-12-14 Added SYNONYM BCKDH phosphatase
2007-12-14 Added SYNONYM HMG-CoA reductase phosphatase
2007-09-06 Added SYNONYM serine/threonine specific protein phosphatase activity
2004-03-03 Updated DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2002-11-27 Added DEFINITION Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004721 (phosphoprotein phosphatase activity)

Cross-references

Timestamp Action Category Detail
2010-10-08 Deleted XREF MetaCyc:3.1.3.16-RXN
2009-05-21 Added XREF MetaCyc:3.1.3.16-RXN
2003-11-05 Deleted XREF MetaCyc:3.1.3.16-RXN
2003-11-05 Deleted XREF EC:3.1.3.16
2003-10-27 Added XREF MetaCyc:3.1.3.16-RXN
2001-03-30 Added XREF EC:3.1.3.16

Other

Timestamp Action Category Detail
2008-02-14 Added SECONDARY GO:0030361 (protein phosphatase type 4, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0030358 (protein phosphatase type 2B, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0030357 (protein phosphatase type 2B activity)
2008-02-14 Added SECONDARY GO:0015071 (protein phosphatase type 2C activity)
2008-02-14 Added SECONDARY GO:0008600 (protein phosphatase type 2A, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0008598 (protein phosphatase type 1, intrinsic catalyst activity)
2008-02-14 Added SECONDARY GO:0000163 (protein phosphatase type 1 activity)
2008-02-14 Added SECONDARY GO:0000158 (protein phosphatase type 2A activity)
2008-02-14 Added SECONDARY GO:0030360 (protein phosphatase type 4 activity)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
16ms