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GO:0000155 phosphorelay sensor kinase activity

Term Information

ID GO:0000155
Name phosphorelay sensor kinase activity
Ontology Molecular Function
Definition Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
PMID:10966457 PMID:20223701 PMID:9191038
GONUTS GO:0000155 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow two-component sensor molecule
narrow two-component system sensor activity
narrow two-component sensor activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.3.-
InterPro IPR000700
InterPro IPR003661
InterPro IPR003755
InterPro IPR003852
InterPro IPR004105
InterPro IPR008358
InterPro IPR010559
InterPro IPR010808
InterPro IPR011104
InterPro IPR011126
InterPro IPR011620
InterPro IPR011712
InterPro IPR014302
InterPro IPR014310
InterPro IPR014409
InterPro IPR014525
InterPro IPR016120
InterPro IPR016380
InterPro IPR016381
InterPro IPR017202
InterPro IPR017203

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000155:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000155. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000155 based on the entire annotation set Co-occurrence statistics for GO:0000155 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-09-18 Added RELATION is a GO:0005057 (receptor signaling protein activity)
2012-12-07 Deleted SYNONYM two-component system sensor activity
2012-12-07 Added SYNONYM two-component system sensor activity
2012-12-07 Added SYNONYM two-component sensor activity
2012-12-07 Updated TERM phosphorelay sensor kinase activity
2012-03-29 Added RELATION is a GO:0038023 (signaling receptor activity)
2012-03-29 Deleted RELATION is a GO:0004871 (signal transducer activity)
2012-01-14 Added RELATION part of GO:0023014 (signal transduction by phosphorylation)
2010-10-29 Deleted DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.
2010-10-29 Added DEFINITION Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
2010-10-29 Added RELATION part of GO:0000160 (phosphorelay signal transduction system)
2008-05-13 Added DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.
2008-05-12 Deleted DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.
2008-04-01 Updated RELATION is a GO:0004871 (signal transducer activity)
2008-04-01 Updated RELATION is a GO:0004673 (protein histidine kinase activity)
2007-08-09 Added SYNONYM two-component sensor molecule
2007-08-09 Added SYNONYM two-component system sensor activity
2007-08-09 Deleted SYNONYM two-component sensor molecule
2007-08-09 Deleted SYNONYM two-component system sensor activity
2006-02-19 Added SYNONYM two-component system sensor activity
2006-02-19 Updated TERM two-component sensor activity
2006-02-19 Added SYNONYM two-component sensor molecule
2005-09-24 Added DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.
2003-03-19 Updated TERM two-component sensor molecule activity
2002-02-06 Updated TERM two-component sensor molecule
2001-04-03 Updated TERM two-component sensor molecule
2001-03-30 Added XREF EC:2.7.3.-
2001-03-30 Added TERM two-component sensor molecule

Term

Timestamp Action Category Detail
2012-12-07 Updated TERM phosphorelay sensor kinase activity
2006-02-19 Updated TERM two-component sensor activity
2003-03-19 Updated TERM two-component sensor molecule activity
2002-02-06 Updated TERM two-component sensor molecule
2001-04-03 Updated TERM two-component sensor molecule
2001-03-30 Added TERM two-component sensor molecule

Definition/synonyms

Timestamp Action Category Detail
2012-12-07 Deleted SYNONYM two-component system sensor activity
2012-12-07 Added SYNONYM two-component system sensor activity
2012-12-07 Added SYNONYM two-component sensor activity
2010-10-29 Deleted DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.
2010-10-29 Added DEFINITION Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
2008-05-13 Added DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.
2008-05-12 Deleted DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.
2007-08-09 Added SYNONYM two-component sensor molecule
2007-08-09 Added SYNONYM two-component system sensor activity
2007-08-09 Deleted SYNONYM two-component sensor molecule
2007-08-09 Deleted SYNONYM two-component system sensor activity
2006-02-19 Added SYNONYM two-component system sensor activity
2006-02-19 Added SYNONYM two-component sensor molecule
2005-09-24 Added DEFINITION Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell.

Relationships

Timestamp Action Category Detail
2014-09-18 Added RELATION is a GO:0005057 (receptor signaling protein activity)
2012-03-29 Added RELATION is a GO:0038023 (signaling receptor activity)
2012-03-29 Deleted RELATION is a GO:0004871 (signal transducer activity)
2012-01-14 Added RELATION part of GO:0023014 (signal transduction by phosphorylation)
2010-10-29 Added RELATION part of GO:0000160 (phosphorelay signal transduction system)
2008-04-01 Updated RELATION is a GO:0004871 (signal transducer activity)
2008-04-01 Updated RELATION is a GO:0004673 (protein histidine kinase activity)

Cross-references

Timestamp Action Category Detail
2001-03-30 Added XREF EC:2.7.3.-
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