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GO:0000124 SAGA complex

A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery.

Term Information

ID GO:0000124
Name SAGA complex
Ontology Cellular Component
Definition A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery.
Comment

Synonyms

Type Synonym
exact Spt-Ada-Gcn5-acetyltransferase complex

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Ancestor Table

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GO:0005575 cellular_component
GO:0043226 organelle
GO:0005623 cell
GO:0032991 macromolecular complex
GO:0031974 membrane-enclosed lumen
GO:0043234 protein complex
GO:0044422 organelle part
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0005622 intracellular
GO:0043233 organelle lumen
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0044446 intracellular organelle part
GO:0005634 nucleus
GO:0070013 intracellular organelle lumen
GO:0044428 nuclear part
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0044451 nucleoplasm part
GO:0000123 histone acetyltransferase complex
GO:0070461 SAGA-type complex
GO:0000124 SAGA complex

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Co-occurring Terms

Co-occurrence statistics

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