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GO:0000082 G1/S transition of mitotic cell cycle

Term Information

ID GO:0000082
Name G1/S transition of mitotic cell cycle
Ontology Biological Process
Definition The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
GONUTS GO:0000082 Wiki Page

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
cell cycleLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0010029 GO:0044770 cell cycle phase transition only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR028315
InterPro IPR028858

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000082:
Relationship To GO:0000082 Child Term Child Term Name
Part of GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
Regulates GO:2000045 regulation of G1/S transition of mitotic cell cycle
Negatively regulates GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
Positively regulates GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
Part of GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
Part of GO:0031658 negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
Part of GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0000082. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0000082 based on the entire annotation set Co-occurrence statistics for GO:0000082 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-03-27 Added RELATION is a GO:0044843 (cell cycle G1/S phase transition)
2013-10-10 Deleted RELATION part of GO:0051329 (mitotic interphase)
2013-03-03 Added DEFINITION The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
2013-03-03 Deleted DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2013-03-03 Deleted RELATION is a GO:0022402 (cell cycle process)
2013-03-03 Added RELATION is a GO:0044772 (mitotic cell cycle phase transition)
2008-05-13 Added DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2008-05-12 Deleted DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2008-04-01 Updated RELATION is a GO:0022402 (cell cycle process)
2008-04-01 Updated RELATION part of GO:0051329 (mitotic interphase)
2004-10-13 Updated DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2002-02-06 Updated TERM G1/S transition of mitotic cell cycle
2001-08-06 Added DEFINITION Progression from G1 phase to S phase of the standard mitotic cell cycle.
2001-04-03 Updated TERM G1/S transition of mitotic cell cycle
2001-03-30 Added TERM G1/S transition of mitotic cell cycle

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM G1/S transition of mitotic cell cycle
2001-04-03 Updated TERM G1/S transition of mitotic cell cycle
2001-03-30 Added TERM G1/S transition of mitotic cell cycle

Definition/synonyms

Timestamp Action Category Detail
2013-03-03 Added DEFINITION The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
2013-03-03 Deleted DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2008-05-13 Added DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2008-05-12 Deleted DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2004-10-13 Updated DEFINITION Progression from G1 phase to S phase of the mitotic cell cycle.
2001-08-06 Added DEFINITION Progression from G1 phase to S phase of the standard mitotic cell cycle.

Relationships

Timestamp Action Category Detail
2014-03-27 Added RELATION is a GO:0044843 (cell cycle G1/S phase transition)
2013-10-10 Deleted RELATION part of GO:0051329 (mitotic interphase)
2013-03-03 Deleted RELATION is a GO:0022402 (cell cycle process)
2013-03-03 Added RELATION is a GO:0044772 (mitotic cell cycle phase transition)
2008-04-01 Updated RELATION is a GO:0022402 (cell cycle process)
2008-04-01 Updated RELATION part of GO:0051329 (mitotic interphase)
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