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GO:0000073 spindle pole body separation

A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.

Term Information

ID GO:0000073
Name spindle pole body separation
Ontology Biological Process
Definition A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.
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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0016043 cellular component organization
GO:0007017 microtubule-based process
GO:0007049 cell cycle
GO:0022402 cell cycle process
GO:0006996 organelle organization
GO:0007010 cytoskeleton organization
GO:0000226 microtubule cytoskeleton organization
GO:0031023 microtubule organizing center organization
GO:0051300 spindle pole body organization
GO:0000073 spindle pole body separation

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0010695 regulation of spindle pole body separation
PR GO:0010696 positive regulation of spindle pole body separation
NR GO:0010697 negative regulation of spindle pole body separation

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
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Taxonomy
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Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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