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GO Term History: Displaying 16 audit records for all terms for the date 2014-04-12

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2014-04-12 GO:0006915 apoptotic process Deleted DEFINITION A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase, and an execution phase, which is triggered by the former.
2014-04-12 GO:0019511 peptidyl-proline hydroxylation Added RELATION is a GO:0018126 (protein hydroxylation)
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added DEFINITION A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce "residual bodies". Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from "excessive residual cytoplasm" that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.
2014-04-12 GO:0006915 apoptotic process Added DEFINITION A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
2014-04-12 GO:0097194 execution phase of apoptosis Added DEFINITION A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added TERM sperm cytoplasmic droplet
2014-04-12 GO:0031543 peptidyl-proline dioxygenase activity Added RELATION part of GO:0019511 (peptidyl-proline hydroxylation)
2014-04-12 GO:0031510 SUMO activating enzyme complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0033620 Mei2 nuclear dot complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0000441 SSL2-core TFIIH complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0008024 positive transcription elongation factor complex b Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added SYNONYM sperm residual cytoplasm
2014-04-12 GO:1990251 Mmi1 nuclear focus complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:1990354 activated SUMO-E1 ligase complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added RELATION is a GO:0097223 (sperm part)
2014-04-12 GO:0097194 execution phase of apoptosis Deleted DEFINITION A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The execution phase ends when the cell has died.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added TERM sperm cytoplasmic droplet

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2014-04-12 GO:0006915 apoptotic process Deleted DEFINITION A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase, and an execution phase, which is triggered by the former.
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added DEFINITION A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce "residual bodies". Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from "excessive residual cytoplasm" that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.
2014-04-12 GO:0006915 apoptotic process Added DEFINITION A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
2014-04-12 GO:0097194 execution phase of apoptosis Added DEFINITION A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added SYNONYM sperm residual cytoplasm
2014-04-12 GO:0097194 execution phase of apoptosis Deleted DEFINITION A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The execution phase ends when the cell has died.

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2014-04-12 GO:0019511 peptidyl-proline hydroxylation Added RELATION is a GO:0018126 (protein hydroxylation)
2014-04-12 GO:0031543 peptidyl-proline dioxygenase activity Added RELATION part of GO:0019511 (peptidyl-proline hydroxylation)
2014-04-12 GO:0031510 SUMO activating enzyme complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0033620 Mei2 nuclear dot complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0000441 SSL2-core TFIIH complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0008024 positive transcription elongation factor complex b Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:1990251 Mmi1 nuclear focus complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:1990354 activated SUMO-E1 ligase complex Deleted RELATION part of GO:0005634 (nucleus)
2014-04-12 GO:0097598 sperm cytoplasmic droplet Added RELATION is a GO:0097223 (sperm part)
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