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GO Term History: Displaying 47 audit records for all terms for the date 2011-11-02

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted RELATION is a GO:0010952 (positive regulation of peptidase activity)
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION is a GO:2000117 (negative regulation of cysteine-type endopeptidase activity)
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION part of GO:0006915 (apoptotic process)
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted RELATION is a GO:0010466 (negative regulation of peptidase activity)
2011-11-02 GO:0004197 cysteine-type endopeptidase activity Added SYNONYM caspase activity
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Added SYNONYM caspase activator activity
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Added SYNONYM caspase inhibitor activity
2011-11-02 GO:0004197 cysteine-type endopeptidase activity Added SYNONYM metacaspase activity
2011-11-02 GO:0036032 neural crest cell delamination Added SYNONYM neural crest cell emigration
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added SYNONYM negative regulation of caspase activity
2011-11-02 GO:0036032 neural crest cell delamination Added SYNONYM neural crest cell segregation
2011-11-02 GO:0036032 neural crest cell delamination Added SYNONYM neural crest cell individualization
2011-11-02 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process Added SYNONYM metacaspase activity
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added SYNONYM positive regulation of caspase activity
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Added SYNONYM caspase regulator activity
2011-11-02 GO:0036032 neural crest cell delamination Added RELATION is a GO:0060232 (delamination)
2011-11-02 GO:0036033 mediator complex binding Added RELATION is a GO:0032403 (protein complex binding)
2011-11-02 GO:0036034 mediator complex assembly Added RELATION is a GO:0043623 (cellular protein complex assembly)
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Updated TERM cysteine-type endopeptidase activator activity involved in apoptotic process
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Updated TERM cysteine-type endopeptidase inhibitor activity involved in apoptotic process
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Updated TERM cysteine-type endopeptidase regulator activity involved in apoptotic process
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Updated TERM negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Updated TERM positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
2011-11-02 GO:0036032 neural crest cell delamination Added TERM neural crest cell delamination
2011-11-02 GO:0036033 mediator complex binding Added TERM mediator complex binding
2011-11-02 GO:0036034 mediator complex assembly Added TERM mediator complex assembly
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Added DEFINITION Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0008303 caspase complex Added DEFINITION A protein complex that is located in the cytosol and acts as a cysteine-type endopeptidase involved in the apoptotic process; the peptidase activity has specificity for the hydrolysis of aspartyl bonds.
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added DEFINITION Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Deleted DEFINITION Stops, prevents or reduces the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
2011-11-02 GO:0060234 neuroblast delamination Deleted DEFINITION The negative regulation of cell adhesion process in which a neuroblast slits off of a neurectodermal sheet.
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Deleted DEFINITION Modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Deleted DEFINITION Increases the rate of proteolysis catalyzed by a caspase.
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted DEFINITION Any process that activates or increases the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
2011-11-02 GO:0071619 phosphorylation of RNA polymerase II C-terminal domain serine 2 residues Deleted DEFINITION The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser5 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of caspase activity.
2011-11-02 GO:0008303 caspase complex Deleted DEFINITION A protein complex that is located in the cytosol and acts as a cysteine-type endopeptidase are involved in apoptosis; the peptidase activity has specificity for the hydrolysis of aspartyl bonds.
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
2011-11-02 GO:0036032 neural crest cell delamination Added DEFINITION The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Added DEFINITION Increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0036033 mediator complex binding Added DEFINITION Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Added DEFINITION Modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0060234 neuroblast delamination Added DEFINITION The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.
2011-11-02 GO:0071619 phosphorylation of RNA polymerase II C-terminal domain serine 2 residues Added DEFINITION The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.
2011-11-02 GO:0036034 mediator complex assembly Added DEFINITION The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION is a GO:2001056 (positive regulation of cysteine-type endopeptidase activity)
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION part of GO:0006915 (apoptotic process)

Terms

Timestamp GO ID GO Term Name Action Category Detail
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Updated TERM cysteine-type endopeptidase activator activity involved in apoptotic process
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Updated TERM cysteine-type endopeptidase inhibitor activity involved in apoptotic process
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Updated TERM cysteine-type endopeptidase regulator activity involved in apoptotic process
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Updated TERM negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Updated TERM positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
2011-11-02 GO:0036032 neural crest cell delamination Added TERM neural crest cell delamination
2011-11-02 GO:0036033 mediator complex binding Added TERM mediator complex binding
2011-11-02 GO:0036034 mediator complex assembly Added TERM mediator complex assembly

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2011-11-02 GO:0004197 cysteine-type endopeptidase activity Added SYNONYM caspase activity
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Added SYNONYM caspase activator activity
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Added SYNONYM caspase inhibitor activity
2011-11-02 GO:0004197 cysteine-type endopeptidase activity Added SYNONYM metacaspase activity
2011-11-02 GO:0036032 neural crest cell delamination Added SYNONYM neural crest cell emigration
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added SYNONYM negative regulation of caspase activity
2011-11-02 GO:0036032 neural crest cell delamination Added SYNONYM neural crest cell segregation
2011-11-02 GO:0036032 neural crest cell delamination Added SYNONYM neural crest cell individualization
2011-11-02 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process Added SYNONYM metacaspase activity
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added SYNONYM positive regulation of caspase activity
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Added SYNONYM caspase regulator activity
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Added DEFINITION Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0008303 caspase complex Added DEFINITION A protein complex that is located in the cytosol and acts as a cysteine-type endopeptidase involved in the apoptotic process; the peptidase activity has specificity for the hydrolysis of aspartyl bonds.
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added DEFINITION Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Deleted DEFINITION Stops, prevents or reduces the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
2011-11-02 GO:0060234 neuroblast delamination Deleted DEFINITION The negative regulation of cell adhesion process in which a neuroblast slits off of a neurectodermal sheet.
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Deleted DEFINITION Modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Deleted DEFINITION Increases the rate of proteolysis catalyzed by a caspase.
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted DEFINITION Any process that activates or increases the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
2011-11-02 GO:0071619 phosphorylation of RNA polymerase II C-terminal domain serine 2 residues Deleted DEFINITION The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser5 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of caspase activity.
2011-11-02 GO:0008303 caspase complex Deleted DEFINITION A protein complex that is located in the cytosol and acts as a cysteine-type endopeptidase are involved in apoptosis; the peptidase activity has specificity for the hydrolysis of aspartyl bonds.
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
2011-11-02 GO:0036032 neural crest cell delamination Added DEFINITION The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.
2011-11-02 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Added DEFINITION Increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0036033 mediator complex binding Added DEFINITION Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
2011-11-02 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process Added DEFINITION Modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2011-11-02 GO:0060234 neuroblast delamination Added DEFINITION The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.
2011-11-02 GO:0071619 phosphorylation of RNA polymerase II C-terminal domain serine 2 residues Added DEFINITION The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.
2011-11-02 GO:0036034 mediator complex assembly Added DEFINITION The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted RELATION is a GO:0010952 (positive regulation of peptidase activity)
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION is a GO:2000117 (negative regulation of cysteine-type endopeptidase activity)
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION part of GO:0006915 (apoptotic process)
2011-11-02 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Deleted RELATION is a GO:0010466 (negative regulation of peptidase activity)
2011-11-02 GO:0036032 neural crest cell delamination Added RELATION is a GO:0060232 (delamination)
2011-11-02 GO:0036033 mediator complex binding Added RELATION is a GO:0032403 (protein complex binding)
2011-11-02 GO:0036034 mediator complex assembly Added RELATION is a GO:0043623 (cellular protein complex assembly)
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION is a GO:2001056 (positive regulation of cysteine-type endopeptidase activity)
2011-11-02 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Added RELATION part of GO:0006915 (apoptotic process)
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