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GO Term History: Displaying 181 audit records for all terms for the date 2011-10-24

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added DEFINITION Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Added DEFINITION The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.
2011-10-24 GO:0001647 G-protein coupled cytokinin receptor activity Added DEFINITION Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Added DEFINITION Any series of molecular signals initiated by an extracellular signal combining with a receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2011-10-24 GO:0035110 leg morphogenesis Added DEFINITION OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0035286 leg segmentation Added DEFINITION OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint.
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Added DEFINITION Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0005892 acetylcholine-gated channel complex Added DEFINITION A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
2011-10-24 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity Added DEFINITION Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
2011-10-24 GO:0008020 G-protein coupled photoreceptor activity Added DEFINITION Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0008227 G-protein coupled amine receptor activity Added DEFINITION Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added DEFINITION Interacting selectively and non-covalently with a G-protein coupled acetylcholine receptor.
2011-10-24 GO:0035111 leg joint morphogenesis Added DEFINITION OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Added DEFINITION Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Added DEFINITION Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Added DEFINITION Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted DEFINITION Combining with acetylcholine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of muscarinic receptors.
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M1 muscarinic acetylcholine receptor.
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M2 muscarinic acetylcholine receptor.
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M3 muscarinic acetylcholine receptor.
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M4 muscarinic acetylcholine receptor.
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M5 muscarinic acetylcholine receptor.
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Deleted DEFINITION Combining with a chemoattractant peptide to initiate a G-protein mediated change in cell activity.
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Updated TERM G-protein coupled olfactory receptor activity
2011-10-24 GO:0046590 embryonic leg morphogenesis Updated TERM embryonic leg morphogenesis
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Updated TERM embryonic leg joint morphogenesis
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Updated TERM G-protein coupled purinergic nucleotide receptor activity
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Updated TERM G-protein coupled pyrimidinergic nucleotide receptor activity
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Updated TERM skeletal muscle acetylcholine-gated channel clustering
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Updated TERM inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Updated TERM activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Updated TERM G-protein coupled acetylcholine receptor signaling pathway
2011-10-24 GO:0005892 acetylcholine-gated channel complex Updated TERM acetylcholine-gated channel complex
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted TERM muscarinic acetylcholine receptor activity
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Updated TERM acetylcholine-activated cation-selective channel activity
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Updated TERM G-protein coupled chemoattractant receptor activity
2011-10-24 GO:0001664 G-protein coupled receptor binding Updated TERM G-protein coupled receptor binding
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Updated TERM G-protein coupled nucleotide receptor activity
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Updated TERM G-protein coupled adenosine receptor activity
2011-10-24 GO:0016492 G-protein coupled neurotensin receptor activity Updated TERM G-protein coupled neurotensin receptor activity
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Updated TERM G-protein coupled peptide receptor activity
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Updated TERM G-protein coupled receptor signaling pathway
2011-10-24 GO:0035286 leg segmentation Updated TERM leg segmentation
2011-10-24 GO:0035110 leg morphogenesis Updated TERM leg morphogenesis
2011-10-24 GO:0035111 leg joint morphogenesis Updated TERM leg joint morphogenesis
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Updated TERM G-protein coupled acetylcholine receptor binding
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted TERM M1 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted TERM M2 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted TERM M3 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted TERM M4 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted TERM M5 muscarinic acetylcholine receptor binding
2011-10-24 GO:0016492 G-protein coupled neurotensin receptor activity Deleted SYNONYM G-protein coupled neurotensin receptor activity
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Added SYNONYM activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M5 muscarinic acetylcholine receptor binding
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Added SYNONYM purinergic nucleotide receptor activity, G-protein coupled
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Added SYNONYM skeletal muscle nicotinic acetylcholine receptor clustering
2011-10-24 GO:0005892 acetylcholine-gated channel complex Added SYNONYM nicotinic acetylcholine-gated receptor-channel complex
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added SYNONYM muscarinic acetylcholine receptor activity
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Added SYNONYM pyrimidinergic nucleotide receptor activity, G-protein coupled
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Added SYNONYM G-protein chemoattractant receptor activity
2011-10-24 GO:0016492 G-protein coupled neurotensin receptor activity Added SYNONYM neurotensin receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M1 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M3 muscarinic acetylcholine receptor binding
2011-10-24 GO:0004930 G-protein coupled receptor activity Added SYNONYM receptor activity, G-protein coupled
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Added SYNONYM peptide receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M1 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M3 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M5 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Added SYNONYM olfactory receptor activity, G-protein coupled
2011-10-24 GO:0001664 G-protein coupled receptor binding Added SYNONYM G-protein-coupled receptor binding
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Added SYNONYM inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M2 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Added SYNONYM nucleotide receptor activity, G-protein coupled
2011-10-24 GO:0001647 G-protein coupled cytokinin receptor activity Added SYNONYM cytokinin receptor activity, G-protein coupled
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Added SYNONYM nicotinic acetylcholine-activated cation-selective channel activity
2011-10-24 GO:0008020 G-protein coupled photoreceptor activity Added SYNONYM photoreceptor activity, G-protein coupled
2011-10-24 GO:0004930 G-protein coupled receptor activity Added DEFINITION Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0004935 adrenergic receptor activity Added DEFINITION Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.
2011-10-24 GO:0046590 embryonic leg morphogenesis Added DEFINITION OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0001664 G-protein coupled receptor binding Added DEFINITION Interacting selectively and non-covalently with a G-protein coupled receptor.
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted DEFINITION The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner.
2011-10-24 GO:0001647 G-protein coupled cytokinin receptor activity Deleted DEFINITION Combining with a cytokinin to initiate a change in cell activity. The receptor is G-protein coupled.
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a muscarinic acetylcholine receptor.
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2011-10-24 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity Deleted DEFINITION A G-protein coupled receptor that binds glutamate and inhibits adenylate cyclase activity.
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Deleted DEFINITION Combining with an odorant and transmitting the signal to a heterotrimeric G-protein complex, to initiate a change in cell activity in response to detection of smell.
2011-10-24 GO:0008020 G-protein coupled photoreceptor activity Deleted DEFINITION A G-protein coupled receptor that responds to incidental electromagnetic radiation, particularly visible light.
2011-10-24 GO:0004935 adrenergic receptor activity Deleted DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity.
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Deleted DEFINITION Combining with acetylcholine to initiate a change in cell activity via activation of a G protein.
2011-10-24 GO:0008227 G-protein coupled amine receptor activity Deleted DEFINITION A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2011-10-24 GO:0004930 G-protein coupled receptor activity Deleted DEFINITION A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
2011-10-24 GO:0001664 G-protein coupled receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a G-protein-coupled receptor.
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Deleted DEFINITION Combining with a purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Deleted DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2011-10-24 GO:0005892 acetylcholine-gated channel complex Deleted DEFINITION A protein complex that acts as an acetylcholine receptor, and forms a transmembrane channel through which ions may pass in response to ligand binding. The complex is a homo- or heteropentamer of subunits that are members of a neurotransmitter receptor superfamily.
2011-10-24 GO:0045125 bioactive lipid receptor activity Deleted DEFINITION Combining with a bioactive lipid to initiate a change in cell activity. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.
2011-10-24 GO:0046590 embryonic leg morphogenesis Deleted DEFINITION The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Deleted DEFINITION The accumulation of acetylcholine receptors (AChRs) in a narrow, central region of muscle fibers, in apposition to nerve terminals.
2011-10-24 GO:0035111 leg joint morphogenesis Deleted DEFINITION The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Deleted DEFINITION Combining with a pyrimidine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0035110 leg morphogenesis Deleted DEFINITION The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Deleted DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that acts as a nicotinic acetylcholine receptor, and opens upon binding acetylcholine.
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Deleted DEFINITION Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.
2011-10-24 GO:0035286 leg segmentation Deleted DEFINITION Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint.
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Deleted DEFINITION Receiving a nucleotide or nucleotide derivative, and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Added DEFINITION Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Added DEFINITION Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0045125 bioactive lipid receptor activity Added DEFINITION Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Added DEFINITION OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner.
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Added DEFINITION Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Added DEFINITION Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031794 (M5 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031793 (M4 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031792 (M3 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031791 (M2 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031790 (M1 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added SECONDARY GO:0004981 (muscarinic acetylcholine receptor activity)
2011-10-24 GO:0035286 leg segmentation Added OBSOLETION consider GO:0035285 (appendage segmentation)
2011-10-24 GO:0035286 leg segmentation Added OBSOLETION consider GO:0036011 (imaginal disc-derived leg segmentation)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Added OBSOLETION consider GO:0036023 (embryonic skeletal limb joint morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Added OBSOLETION consider GO:0036023 (embryonic skeletal limb joint morphogenesis)
2011-10-24 GO:0046590 embryonic leg morphogenesis Added OBSOLETION consider GO:0030326 (embryonic limb morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Added OBSOLETION consider GO:0035108 (limb morphogenesis)
2011-10-24 GO:0046590 embryonic leg morphogenesis Added OBSOLETION consider GO:0035116 (embryonic hindlimb morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Added OBSOLETION consider GO:0035137 (hindlimb morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Added OBSOLETION consider GO:0007480 (imaginal disc-derived leg morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Added OBSOLETION consider GO:0016348 (imaginal disc-derived leg joint morphogenesis)
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Added RELATION part of GO:0001941 (postsynaptic membrane organization)
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Deleted RELATION is a GO:0001941 (postsynaptic membrane organization)
2011-10-24 GO:0046590 embryonic leg morphogenesis Deleted RELATION is a GO:0030326 (embryonic limb morphogenesis)
2011-10-24 GO:0046590 embryonic leg morphogenesis Deleted RELATION is a GO:0035110 (leg morphogenesis)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted RELATION is a GO:0048598 (embryonic morphogenesis)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted RELATION is a GO:0035111 (leg joint morphogenesis)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted RELATION part of GO:0046590 (embryonic leg morphogenesis)
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0036011 imaginal disc-derived leg segmentation Added RELATION is a GO:0035285 (appendage segmentation)
2011-10-24 GO:0036011 imaginal disc-derived leg segmentation Deleted RELATION is a GO:0035286 (leg segmentation)
2011-10-24 GO:0035286 leg segmentation Deleted RELATION is a GO:0035285 (appendage segmentation)
2011-10-24 GO:0035286 leg segmentation Deleted RELATION part of GO:0035110 (leg morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Deleted RELATION is a GO:0035108 (limb morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Deleted RELATION is a GO:0036022 (limb joint morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Deleted RELATION is a GO:0009653 (anatomical structure morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Deleted RELATION part of GO:0035286 (leg segmentation)
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added RELATION part of GO:0007213 (G-protein coupled acetylcholine receptor signaling pathway)
2011-10-24 GO:0016348 imaginal disc-derived leg joint morphogenesis Added RELATION is a GO:0036022 (limb joint morphogenesis)
2011-10-24 GO:0016348 imaginal disc-derived leg joint morphogenesis Deleted RELATION is a GO:0035111 (leg joint morphogenesis)
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted RELATION is a GO:0016907 (G-protein coupled acetylcholine receptor activity)
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted RELATION part of GO:0007213 (G-protein coupled acetylcholine receptor signaling pathway)
2011-10-24 GO:0007480 imaginal disc-derived leg morphogenesis Deleted RELATION is a GO:0035110 (leg morphogenesis)
2011-10-24 GO:0000988 protein binding transcription factor activity Added RELATION part of GO:2001141 (regulation of RNA biosynthetic process)
2011-10-24 GO:0000988 protein binding transcription factor activity Deleted RELATION part of GO:0006355 (regulation of transcription, DNA-templated)
2011-10-24 GO:0004930 G-protein coupled receptor activity Added XREF Wikipedia:GPCR
2011-10-24 GO:0008227 G-protein coupled amine receptor activity Added SYNONYM amine receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M4 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Added SYNONYM adenosine receptor activity, G-protein coupled
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Added SYNONYM muscarinic acetylcholine receptor signaling pathway
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added SYNONYM acetylcholine receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M2 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M4 muscarinic acetylcholine receptor binding
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Added SYNONYM G-protein coupled receptor protein signaling pathway
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM muscarinic acetylcholine receptor binding
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted SYNONYM M1 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted SYNONYM M2 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted SYNONYM M3 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted SYNONYM M4 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted SYNONYM M5 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Deleted SYNONYM G-protein coupled purinergic nucleotide receptor activity
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Deleted SYNONYM G-protein coupled peptide receptor activity
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Deleted SYNONYM G-protein coupled olfactory receptor activity
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Deleted SYNONYM G-protein coupled chemoattractant receptor activity
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Deleted SYNONYM G-protein coupled pyrimidinergic nucleotide receptor activity

Terms

Timestamp GO ID GO Term Name Action Category Detail
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Updated TERM G-protein coupled olfactory receptor activity
2011-10-24 GO:0046590 embryonic leg morphogenesis Updated TERM embryonic leg morphogenesis
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Updated TERM embryonic leg joint morphogenesis
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Updated TERM G-protein coupled purinergic nucleotide receptor activity
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Updated TERM G-protein coupled pyrimidinergic nucleotide receptor activity
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Updated TERM skeletal muscle acetylcholine-gated channel clustering
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Updated TERM inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Updated TERM activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Updated TERM G-protein coupled acetylcholine receptor signaling pathway
2011-10-24 GO:0005892 acetylcholine-gated channel complex Updated TERM acetylcholine-gated channel complex
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted TERM muscarinic acetylcholine receptor activity
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Updated TERM acetylcholine-activated cation-selective channel activity
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Updated TERM G-protein coupled chemoattractant receptor activity
2011-10-24 GO:0001664 G-protein coupled receptor binding Updated TERM G-protein coupled receptor binding
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Updated TERM G-protein coupled nucleotide receptor activity
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Updated TERM G-protein coupled adenosine receptor activity
2011-10-24 GO:0016492 G-protein coupled neurotensin receptor activity Updated TERM G-protein coupled neurotensin receptor activity
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Updated TERM G-protein coupled peptide receptor activity
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Updated TERM G-protein coupled receptor signaling pathway
2011-10-24 GO:0035286 leg segmentation Updated TERM leg segmentation
2011-10-24 GO:0035110 leg morphogenesis Updated TERM leg morphogenesis
2011-10-24 GO:0035111 leg joint morphogenesis Updated TERM leg joint morphogenesis
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Updated TERM G-protein coupled acetylcholine receptor binding
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted TERM M1 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted TERM M2 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted TERM M3 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted TERM M4 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted TERM M5 muscarinic acetylcholine receptor binding

Obsoletions

Timestamp GO ID GO Term Name Action Category Detail
2011-10-24 GO:0035286 leg segmentation Added OBSOLETION consider GO:0035285 (appendage segmentation)
2011-10-24 GO:0035286 leg segmentation Added OBSOLETION consider GO:0036011 (imaginal disc-derived leg segmentation)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Added OBSOLETION consider GO:0036023 (embryonic skeletal limb joint morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Added OBSOLETION consider GO:0036023 (embryonic skeletal limb joint morphogenesis)
2011-10-24 GO:0046590 embryonic leg morphogenesis Added OBSOLETION consider GO:0030326 (embryonic limb morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Added OBSOLETION consider GO:0035108 (limb morphogenesis)
2011-10-24 GO:0046590 embryonic leg morphogenesis Added OBSOLETION consider GO:0035116 (embryonic hindlimb morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Added OBSOLETION consider GO:0035137 (hindlimb morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Added OBSOLETION consider GO:0007480 (imaginal disc-derived leg morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Added OBSOLETION consider GO:0016348 (imaginal disc-derived leg joint morphogenesis)

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added DEFINITION Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Added DEFINITION The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.
2011-10-24 GO:0001647 G-protein coupled cytokinin receptor activity Added DEFINITION Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Added DEFINITION Any series of molecular signals initiated by an extracellular signal combining with a receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Added DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2011-10-24 GO:0035110 leg morphogenesis Added DEFINITION OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0035286 leg segmentation Added DEFINITION OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint.
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Added DEFINITION Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0005892 acetylcholine-gated channel complex Added DEFINITION A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
2011-10-24 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity Added DEFINITION Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
2011-10-24 GO:0008020 G-protein coupled photoreceptor activity Added DEFINITION Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0008227 G-protein coupled amine receptor activity Added DEFINITION Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added DEFINITION Interacting selectively and non-covalently with a G-protein coupled acetylcholine receptor.
2011-10-24 GO:0035111 leg joint morphogenesis Added DEFINITION OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Added DEFINITION Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Added DEFINITION Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Added DEFINITION Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted DEFINITION Combining with acetylcholine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of muscarinic receptors.
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M1 muscarinic acetylcholine receptor.
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M2 muscarinic acetylcholine receptor.
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M3 muscarinic acetylcholine receptor.
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M4 muscarinic acetylcholine receptor.
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a M5 muscarinic acetylcholine receptor.
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Deleted DEFINITION Combining with a chemoattractant peptide to initiate a G-protein mediated change in cell activity.
2011-10-24 GO:0016492 G-protein coupled neurotensin receptor activity Deleted SYNONYM G-protein coupled neurotensin receptor activity
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Added SYNONYM activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M5 muscarinic acetylcholine receptor binding
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Added SYNONYM purinergic nucleotide receptor activity, G-protein coupled
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Added SYNONYM skeletal muscle nicotinic acetylcholine receptor clustering
2011-10-24 GO:0005892 acetylcholine-gated channel complex Added SYNONYM nicotinic acetylcholine-gated receptor-channel complex
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added SYNONYM muscarinic acetylcholine receptor activity
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Added SYNONYM pyrimidinergic nucleotide receptor activity, G-protein coupled
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Added SYNONYM G-protein chemoattractant receptor activity
2011-10-24 GO:0016492 G-protein coupled neurotensin receptor activity Added SYNONYM neurotensin receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M1 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M3 muscarinic acetylcholine receptor binding
2011-10-24 GO:0004930 G-protein coupled receptor activity Added SYNONYM receptor activity, G-protein coupled
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Added SYNONYM peptide receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M1 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M3 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M5 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Added SYNONYM olfactory receptor activity, G-protein coupled
2011-10-24 GO:0001664 G-protein coupled receptor binding Added SYNONYM G-protein-coupled receptor binding
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Added SYNONYM inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M2 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Added SYNONYM nucleotide receptor activity, G-protein coupled
2011-10-24 GO:0001647 G-protein coupled cytokinin receptor activity Added SYNONYM cytokinin receptor activity, G-protein coupled
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Added SYNONYM nicotinic acetylcholine-activated cation-selective channel activity
2011-10-24 GO:0008020 G-protein coupled photoreceptor activity Added SYNONYM photoreceptor activity, G-protein coupled
2011-10-24 GO:0004930 G-protein coupled receptor activity Added DEFINITION Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0004935 adrenergic receptor activity Added DEFINITION Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.
2011-10-24 GO:0046590 embryonic leg morphogenesis Added DEFINITION OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0001664 G-protein coupled receptor binding Added DEFINITION Interacting selectively and non-covalently with a G-protein coupled receptor.
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted DEFINITION The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner.
2011-10-24 GO:0001647 G-protein coupled cytokinin receptor activity Deleted DEFINITION Combining with a cytokinin to initiate a change in cell activity. The receptor is G-protein coupled.
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a muscarinic acetylcholine receptor.
2011-10-24 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate.
2011-10-24 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity Deleted DEFINITION A G-protein coupled receptor that binds glutamate and inhibits adenylate cyclase activity.
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Deleted DEFINITION Combining with an odorant and transmitting the signal to a heterotrimeric G-protein complex, to initiate a change in cell activity in response to detection of smell.
2011-10-24 GO:0008020 G-protein coupled photoreceptor activity Deleted DEFINITION A G-protein coupled receptor that responds to incidental electromagnetic radiation, particularly visible light.
2011-10-24 GO:0004935 adrenergic receptor activity Deleted DEFINITION Combining with epinephrine or norepinephrine to initiate a change in cell activity.
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Deleted DEFINITION Combining with acetylcholine to initiate a change in cell activity via activation of a G protein.
2011-10-24 GO:0008227 G-protein coupled amine receptor activity Deleted DEFINITION A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine.
2011-10-24 GO:0004930 G-protein coupled receptor activity Deleted DEFINITION A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
2011-10-24 GO:0001664 G-protein coupled receptor binding Deleted DEFINITION Interacting selectively and non-covalently with a G-protein-coupled receptor.
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Deleted DEFINITION Combining with a purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Deleted DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP.
2011-10-24 GO:0005892 acetylcholine-gated channel complex Deleted DEFINITION A protein complex that acts as an acetylcholine receptor, and forms a transmembrane channel through which ions may pass in response to ligand binding. The complex is a homo- or heteropentamer of subunits that are members of a neurotransmitter receptor superfamily.
2011-10-24 GO:0045125 bioactive lipid receptor activity Deleted DEFINITION Combining with a bioactive lipid to initiate a change in cell activity. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.
2011-10-24 GO:0046590 embryonic leg morphogenesis Deleted DEFINITION The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Deleted DEFINITION The accumulation of acetylcholine receptors (AChRs) in a narrow, central region of muscle fibers, in apposition to nerve terminals.
2011-10-24 GO:0035111 leg joint morphogenesis Deleted DEFINITION The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Deleted DEFINITION Combining with a pyrimidine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0035110 leg morphogenesis Deleted DEFINITION The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Deleted DEFINITION The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Deleted DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that acts as a nicotinic acetylcholine receptor, and opens upon binding acetylcholine.
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Deleted DEFINITION Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.
2011-10-24 GO:0035286 leg segmentation Deleted DEFINITION Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint.
2011-10-24 GO:0001608 G-protein coupled nucleotide receptor activity Deleted DEFINITION Receiving a nucleotide or nucleotide derivative, and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Added DEFINITION Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0004889 acetylcholine-activated cation-selective channel activity Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Added DEFINITION Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0045125 bioactive lipid receptor activity Added DEFINITION Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Added DEFINITION OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner.
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Added DEFINITION Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Added DEFINITION Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
2011-10-24 GO:0008227 G-protein coupled amine receptor activity Added SYNONYM amine receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M4 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0001609 G-protein coupled adenosine receptor activity Added SYNONYM adenosine receptor activity, G-protein coupled
2011-10-24 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway Added SYNONYM muscarinic acetylcholine receptor signaling pathway
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added SYNONYM acetylcholine receptor activity, G-protein coupled
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M2 muscarinic acetylcholine receptor binding
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM M4 muscarinic acetylcholine receptor binding
2011-10-24 GO:0007186 G-protein coupled receptor signaling pathway Added SYNONYM G-protein coupled receptor protein signaling pathway
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SYNONYM muscarinic acetylcholine receptor binding
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted SYNONYM M1 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted SYNONYM M2 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted SYNONYM M3 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted SYNONYM M4 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted SYNONYM M5 muscarinic acetylcholine receptor ligand
2011-10-24 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Deleted SYNONYM G-protein coupled purinergic nucleotide receptor activity
2011-10-24 GO:0008528 G-protein coupled peptide receptor activity Deleted SYNONYM G-protein coupled peptide receptor activity
2011-10-24 GO:0038022 G-protein coupled olfactory receptor activity Deleted SYNONYM G-protein coupled olfactory receptor activity
2011-10-24 GO:0001637 G-protein coupled chemoattractant receptor activity Deleted SYNONYM G-protein coupled chemoattractant receptor activity
2011-10-24 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity Deleted SYNONYM G-protein coupled pyrimidinergic nucleotide receptor activity

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Added RELATION part of GO:0001941 (postsynaptic membrane organization)
2011-10-24 GO:0071340 skeletal muscle acetylcholine-gated channel clustering Deleted RELATION is a GO:0001941 (postsynaptic membrane organization)
2011-10-24 GO:0046590 embryonic leg morphogenesis Deleted RELATION is a GO:0030326 (embryonic limb morphogenesis)
2011-10-24 GO:0046590 embryonic leg morphogenesis Deleted RELATION is a GO:0035110 (leg morphogenesis)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted RELATION is a GO:0048598 (embryonic morphogenesis)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted RELATION is a GO:0035111 (leg joint morphogenesis)
2011-10-24 GO:0046591 embryonic leg joint morphogenesis Deleted RELATION part of GO:0046590 (embryonic leg morphogenesis)
2011-10-24 GO:0031790 M1 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031791 M2 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031792 M3 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031793 M4 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0031794 M5 muscarinic acetylcholine receptor binding Deleted RELATION is a GO:0031789 (G-protein coupled acetylcholine receptor binding)
2011-10-24 GO:0036011 imaginal disc-derived leg segmentation Added RELATION is a GO:0035285 (appendage segmentation)
2011-10-24 GO:0036011 imaginal disc-derived leg segmentation Deleted RELATION is a GO:0035286 (leg segmentation)
2011-10-24 GO:0035286 leg segmentation Deleted RELATION is a GO:0035285 (appendage segmentation)
2011-10-24 GO:0035286 leg segmentation Deleted RELATION part of GO:0035110 (leg morphogenesis)
2011-10-24 GO:0035110 leg morphogenesis Deleted RELATION is a GO:0035108 (limb morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Deleted RELATION is a GO:0036022 (limb joint morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Deleted RELATION is a GO:0009653 (anatomical structure morphogenesis)
2011-10-24 GO:0035111 leg joint morphogenesis Deleted RELATION part of GO:0035286 (leg segmentation)
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added RELATION part of GO:0007213 (G-protein coupled acetylcholine receptor signaling pathway)
2011-10-24 GO:0016348 imaginal disc-derived leg joint morphogenesis Added RELATION is a GO:0036022 (limb joint morphogenesis)
2011-10-24 GO:0016348 imaginal disc-derived leg joint morphogenesis Deleted RELATION is a GO:0035111 (leg joint morphogenesis)
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted RELATION is a GO:0016907 (G-protein coupled acetylcholine receptor activity)
2011-10-24 GO:0004981 muscarinic acetylcholine receptor activity Deleted RELATION part of GO:0007213 (G-protein coupled acetylcholine receptor signaling pathway)
2011-10-24 GO:0007480 imaginal disc-derived leg morphogenesis Deleted RELATION is a GO:0035110 (leg morphogenesis)
2011-10-24 GO:0000988 protein binding transcription factor activity Added RELATION part of GO:2001141 (regulation of RNA biosynthetic process)
2011-10-24 GO:0000988 protein binding transcription factor activity Deleted RELATION part of GO:0006355 (regulation of transcription, DNA-templated)

Cross-references

Timestamp GO ID GO Term Name Action Category Detail
2011-10-24 GO:0004930 G-protein coupled receptor activity Added XREF Wikipedia:GPCR

Other

Timestamp GO ID GO Term Name Action Category Detail
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031794 (M5 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031793 (M4 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031792 (M3 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031791 (M2 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0031789 G-protein coupled acetylcholine receptor binding Added SECONDARY GO:0031790 (M1 muscarinic acetylcholine receptor binding)
2011-10-24 GO:0016907 G-protein coupled acetylcholine receptor activity Added SECONDARY GO:0004981 (muscarinic acetylcholine receptor activity)
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