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GO Term History: Displaying 77 audit records for all terms for the date 2011-06-12

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2011-06-12 GO:0002184 cytoplasmic translational termination Added TERM cytoplasmic translational termination
2011-06-12 GO:0090409 malonyl-CoA synthetase activity Added TERM malonyl-CoA synthetase activity
2011-06-12 GO:0090410 malonate catabolic process Added TERM malonate catabolic process
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added TERM netrin receptor activity involved in chemoattraction
2011-06-12 GO:0038007 netrin-activated signaling pathway Added TERM netrin-activated signaling pathway
2011-06-12 GO:0030518 intracellular steroid hormone receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of a steroid hormone receptor binding to one of its physiological ligands.
2011-06-12 GO:0005042 netrin receptor activity Added DEFINITION Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2011-06-12 GO:0002184 cytoplasmic translational termination Added DEFINITION The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Added DEFINITION Combining with advanced glycation end-products to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added DEFINITION Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.
2011-06-12 GO:0090410 malonate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added DEFINITION Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.
2011-06-12 GO:0038007 netrin-activated signaling pathway Added DEFINITION The series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell. The pathway begins with binding of a netrin to a cell surface receptor and ends with regulation of a downstream cellular process. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added RELATION is a GO:0005042 (netrin receptor activity)
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added RELATION part of GO:0050918 (positive chemotaxis)
2011-06-12 GO:0038007 netrin-activated signaling pathway Added RELATION is a GO:0007166 (cell surface receptor signaling pathway)
2011-06-12 GO:0060182 apelin receptor activity Added RELATION part of GO:0060183 (apelin receptor signaling pathway)
2011-06-12 GO:0090409 malonyl-CoA synthetase activity Added RELATION is a GO:0016878 (acid-thiol ligase activity)
2011-06-12 GO:0090410 malonate catabolic process Added RELATION is a GO:0043649 (dicarboxylic acid catabolic process)
2011-06-12 GO:2000709 regulation of maintenance of meiotic sister chromatid cohesion, centromeric Added RELATION is a GO:0070602 (regulation of centromeric sister chromatid cohesion)
2011-06-12 GO:2000686 regulation of rubidium ion transmembrane transporter activity Added RELATION is a GO:2000680 (regulation of rubidium ion transport)
2011-06-12 GO:2000702 regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation Added RELATION is a GO:0072106 (regulation of ureteric bud formation)
2011-06-12 GO:2000696 regulation of epithelial cell differentiation involved in kidney development Added RELATION is a GO:0090183 (regulation of kidney development)
2011-06-12 GO:2000718 regulation of maintenance of mitotic sister chromatid cohesion, centromeric Added RELATION is a GO:0070602 (regulation of centromeric sister chromatid cohesion)
2011-06-12 GO:0004923 leukemia inhibitory factor receptor activity Added RELATION part of GO:0048861 (leukemia inhibitory factor signaling pathway)
2011-06-12 GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Added RELATION part of GO:0030522 (intracellular receptor signaling pathway)
2011-06-12 GO:0002180 5-lipoxygenase complex Added RELATION is a GO:0044453 (nuclear membrane part)
2011-06-12 GO:0002180 5-lipoxygenase complex Added RELATION is a GO:0043234 (protein complex)
2011-06-12 GO:0002181 cytoplasmic translation Added RELATION is a GO:0006412 (translation)
2011-06-12 GO:0002182 cytoplasmic translational elongation Added RELATION part of GO:0002181 (cytoplasmic translation)
2011-06-12 GO:0002182 cytoplasmic translational elongation Added RELATION is a GO:0006414 (translational elongation)
2011-06-12 GO:0002183 cytoplasmic translational initiation Added RELATION part of GO:0002181 (cytoplasmic translation)
2011-06-12 GO:0002183 cytoplasmic translational initiation Added RELATION is a GO:0006413 (translational initiation)
2011-06-12 GO:0002184 cytoplasmic translational termination Added RELATION is a GO:0006415 (translational termination)
2011-06-12 GO:0002184 cytoplasmic translational termination Added RELATION part of GO:0002181 (cytoplasmic translation)
2011-06-12 GO:0002154 thyroid hormone mediated signaling pathway Added RELATION is a GO:0030522 (intracellular receptor signaling pathway)
2011-06-12 GO:0008095 inositol-1,4,5-trisphosphate receptor activity Added RELATION part of GO:0048016 (inositol phosphate-mediated signaling)
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added RELATION part of GO:0050919 (negative chemotaxis)
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Deleted RELATION is a GO:0004888 (transmembrane signaling receptor activity)
2011-06-12 GO:0005003 ephrin receptor activity Added RELATION part of GO:0048013 (ephrin receptor signaling pathway)
2011-06-12 GO:0005042 netrin receptor activity Added RELATION part of GO:0038007 (netrin-activated signaling pathway)
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added RELATION is a GO:0005042 (netrin receptor activity)
2011-06-12 GO:0004952 dopamine neurotransmitter receptor activity Added RELATION part of GO:0007212 (dopamine receptor signaling pathway)
2011-06-12 GO:0004963 follicle-stimulating hormone receptor activity Added RELATION part of GO:0042699 (follicle-stimulating hormone signaling pathway)
2011-06-12 GO:0004993 serotonin receptor activity Added RELATION part of GO:0007210 (serotonin receptor signaling pathway)
2011-06-12 GO:0035626 juvenile hormone mediated signaling pathway Added RELATION is a GO:0030522 (intracellular receptor signaling pathway)
2011-06-12 GO:0042071 leucokinin receptor activity Added RELATION part of GO:0009755 (hormone-mediated signaling pathway)
2011-06-12 GO:0005042 netrin receptor activity Deleted DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemotaxis when activated.
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Deleted DEFINITION Combining with advanced glycation end-products to initiate a change in cell activity.
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Deleted DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemorepulsion when activated.
2011-06-12 GO:0043401 steroid hormone mediated signaling pathway Deleted DEFINITION A series of molecular signals mediated by the detection of a steroid hormone.
2011-06-12 GO:0030518 intracellular steroid hormone receptor signaling pathway Deleted DEFINITION Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor.
2011-06-12 GO:0090409 malonyl-CoA synthetase activity Added DEFINITION Catalyzes the reaction: malonate + ATP + coenzyme A -> malonyl-CoA + AMP + diphosphate.
2011-06-12 GO:0002182 cytoplasmic translational elongation Added DEFINITION The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
2011-06-12 GO:0043401 steroid hormone mediated signaling pathway Added DEFINITION A series of molecular signals mediated by a steroid hormone binding to a receptor.
2011-06-12 GO:0002183 cytoplasmic translational initiation Added DEFINITION The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. . This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
2011-06-12 GO:0002180 5-lipoxygenase complex Added DEFINITION An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.
2011-06-12 GO:0002181 cytoplasmic translation Added DEFINITION The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Deleted SYNONYM RAGE receptor activity
2011-06-12 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Deleted SYNONYM beta-hydroxybutyrylcoenzyme A dehydrogenase activity
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin-mediated signaling pathway
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added SYNONYM repulsive netrin receptor activity
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin signaling pathway
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Added SYNONYM AGE receptor activity
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin-activated signal transduction pathway
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added SYNONYM netrin receptor activity involved in positive chemotaxis
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added SYNONYM netrin receptor activity involved in negative chemotaxis
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin-activated signalling pathway
2011-06-12 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Added SYNONYM 3-oxoacyl-thioester reductase activity
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added SYNONYM attractive netrin receptor activity
2011-06-12 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Added SYNONYM beta-hydroxybutyrylcoenzyme A dehydrogenase activity
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Added SYNONYM RAGE activity
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Updated TERM netrin receptor activity involved in chemorepulsion
2011-06-12 GO:0002180 5-lipoxygenase complex Added TERM 5-lipoxygenase complex
2011-06-12 GO:0002181 cytoplasmic translation Added TERM cytoplasmic translation
2011-06-12 GO:0002182 cytoplasmic translational elongation Added TERM cytoplasmic translational elongation
2011-06-12 GO:0002183 cytoplasmic translational initiation Added TERM cytoplasmic translational initiation

Terms

Timestamp GO ID GO Term Name Action Category Detail
2011-06-12 GO:0002184 cytoplasmic translational termination Added TERM cytoplasmic translational termination
2011-06-12 GO:0090409 malonyl-CoA synthetase activity Added TERM malonyl-CoA synthetase activity
2011-06-12 GO:0090410 malonate catabolic process Added TERM malonate catabolic process
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added TERM netrin receptor activity involved in chemoattraction
2011-06-12 GO:0038007 netrin-activated signaling pathway Added TERM netrin-activated signaling pathway
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Updated TERM netrin receptor activity involved in chemorepulsion
2011-06-12 GO:0002180 5-lipoxygenase complex Added TERM 5-lipoxygenase complex
2011-06-12 GO:0002181 cytoplasmic translation Added TERM cytoplasmic translation
2011-06-12 GO:0002182 cytoplasmic translational elongation Added TERM cytoplasmic translational elongation
2011-06-12 GO:0002183 cytoplasmic translational initiation Added TERM cytoplasmic translational initiation

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2011-06-12 GO:0030518 intracellular steroid hormone receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of a steroid hormone receptor binding to one of its physiological ligands.
2011-06-12 GO:0005042 netrin receptor activity Added DEFINITION Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2011-06-12 GO:0002184 cytoplasmic translational termination Added DEFINITION The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Added DEFINITION Combining with advanced glycation end-products to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added DEFINITION Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.
2011-06-12 GO:0090410 malonate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added DEFINITION Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.
2011-06-12 GO:0038007 netrin-activated signaling pathway Added DEFINITION The series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell. The pathway begins with binding of a netrin to a cell surface receptor and ends with regulation of a downstream cellular process. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.
2011-06-12 GO:0005042 netrin receptor activity Deleted DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemotaxis when activated.
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Deleted DEFINITION Combining with advanced glycation end-products to initiate a change in cell activity.
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Deleted DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemorepulsion when activated.
2011-06-12 GO:0043401 steroid hormone mediated signaling pathway Deleted DEFINITION A series of molecular signals mediated by the detection of a steroid hormone.
2011-06-12 GO:0030518 intracellular steroid hormone receptor signaling pathway Deleted DEFINITION Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor.
2011-06-12 GO:0090409 malonyl-CoA synthetase activity Added DEFINITION Catalyzes the reaction: malonate + ATP + coenzyme A -> malonyl-CoA + AMP + diphosphate.
2011-06-12 GO:0002182 cytoplasmic translational elongation Added DEFINITION The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
2011-06-12 GO:0043401 steroid hormone mediated signaling pathway Added DEFINITION A series of molecular signals mediated by a steroid hormone binding to a receptor.
2011-06-12 GO:0002183 cytoplasmic translational initiation Added DEFINITION The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. . This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
2011-06-12 GO:0002180 5-lipoxygenase complex Added DEFINITION An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.
2011-06-12 GO:0002181 cytoplasmic translation Added DEFINITION The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Deleted SYNONYM RAGE receptor activity
2011-06-12 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Deleted SYNONYM beta-hydroxybutyrylcoenzyme A dehydrogenase activity
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin-mediated signaling pathway
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added SYNONYM repulsive netrin receptor activity
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin signaling pathway
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Added SYNONYM AGE receptor activity
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin-activated signal transduction pathway
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added SYNONYM netrin receptor activity involved in positive chemotaxis
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added SYNONYM netrin receptor activity involved in negative chemotaxis
2011-06-12 GO:0038007 netrin-activated signaling pathway Added SYNONYM netrin-activated signalling pathway
2011-06-12 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Added SYNONYM 3-oxoacyl-thioester reductase activity
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added SYNONYM attractive netrin receptor activity
2011-06-12 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Added SYNONYM beta-hydroxybutyrylcoenzyme A dehydrogenase activity
2011-06-12 GO:0050785 advanced glycation end-product receptor activity Added SYNONYM RAGE activity

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added RELATION is a GO:0005042 (netrin receptor activity)
2011-06-12 GO:0038006 netrin receptor activity involved in chemoattraction Added RELATION part of GO:0050918 (positive chemotaxis)
2011-06-12 GO:0038007 netrin-activated signaling pathway Added RELATION is a GO:0007166 (cell surface receptor signaling pathway)
2011-06-12 GO:0060182 apelin receptor activity Added RELATION part of GO:0060183 (apelin receptor signaling pathway)
2011-06-12 GO:0090409 malonyl-CoA synthetase activity Added RELATION is a GO:0016878 (acid-thiol ligase activity)
2011-06-12 GO:0090410 malonate catabolic process Added RELATION is a GO:0043649 (dicarboxylic acid catabolic process)
2011-06-12 GO:2000709 regulation of maintenance of meiotic sister chromatid cohesion, centromeric Added RELATION is a GO:0070602 (regulation of centromeric sister chromatid cohesion)
2011-06-12 GO:2000686 regulation of rubidium ion transmembrane transporter activity Added RELATION is a GO:2000680 (regulation of rubidium ion transport)
2011-06-12 GO:2000702 regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation Added RELATION is a GO:0072106 (regulation of ureteric bud formation)
2011-06-12 GO:2000696 regulation of epithelial cell differentiation involved in kidney development Added RELATION is a GO:0090183 (regulation of kidney development)
2011-06-12 GO:2000718 regulation of maintenance of mitotic sister chromatid cohesion, centromeric Added RELATION is a GO:0070602 (regulation of centromeric sister chromatid cohesion)
2011-06-12 GO:0004923 leukemia inhibitory factor receptor activity Added RELATION part of GO:0048861 (leukemia inhibitory factor signaling pathway)
2011-06-12 GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Added RELATION part of GO:0030522 (intracellular receptor signaling pathway)
2011-06-12 GO:0002180 5-lipoxygenase complex Added RELATION is a GO:0044453 (nuclear membrane part)
2011-06-12 GO:0002180 5-lipoxygenase complex Added RELATION is a GO:0043234 (protein complex)
2011-06-12 GO:0002181 cytoplasmic translation Added RELATION is a GO:0006412 (translation)
2011-06-12 GO:0002182 cytoplasmic translational elongation Added RELATION part of GO:0002181 (cytoplasmic translation)
2011-06-12 GO:0002182 cytoplasmic translational elongation Added RELATION is a GO:0006414 (translational elongation)
2011-06-12 GO:0002183 cytoplasmic translational initiation Added RELATION part of GO:0002181 (cytoplasmic translation)
2011-06-12 GO:0002183 cytoplasmic translational initiation Added RELATION is a GO:0006413 (translational initiation)
2011-06-12 GO:0002184 cytoplasmic translational termination Added RELATION is a GO:0006415 (translational termination)
2011-06-12 GO:0002184 cytoplasmic translational termination Added RELATION part of GO:0002181 (cytoplasmic translation)
2011-06-12 GO:0002154 thyroid hormone mediated signaling pathway Added RELATION is a GO:0030522 (intracellular receptor signaling pathway)
2011-06-12 GO:0008095 inositol-1,4,5-trisphosphate receptor activity Added RELATION part of GO:0048016 (inositol phosphate-mediated signaling)
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added RELATION part of GO:0050919 (negative chemotaxis)
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Deleted RELATION is a GO:0004888 (transmembrane signaling receptor activity)
2011-06-12 GO:0005003 ephrin receptor activity Added RELATION part of GO:0048013 (ephrin receptor signaling pathway)
2011-06-12 GO:0005042 netrin receptor activity Added RELATION part of GO:0038007 (netrin-activated signaling pathway)
2011-06-12 GO:0005043 netrin receptor activity involved in chemorepulsion Added RELATION is a GO:0005042 (netrin receptor activity)
2011-06-12 GO:0004952 dopamine neurotransmitter receptor activity Added RELATION part of GO:0007212 (dopamine receptor signaling pathway)
2011-06-12 GO:0004963 follicle-stimulating hormone receptor activity Added RELATION part of GO:0042699 (follicle-stimulating hormone signaling pathway)
2011-06-12 GO:0004993 serotonin receptor activity Added RELATION part of GO:0007210 (serotonin receptor signaling pathway)
2011-06-12 GO:0035626 juvenile hormone mediated signaling pathway Added RELATION is a GO:0030522 (intracellular receptor signaling pathway)
2011-06-12 GO:0042071 leucokinin receptor activity Added RELATION part of GO:0009755 (hormone-mediated signaling pathway)
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