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GO Term History: Displaying 500 audit records for all terms for the date 2011-02-15

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2011-02-15 GO:0035674 tricarboxylic acid transmembrane transport Added TERM tricarboxylic acid transmembrane transport
2011-02-15 GO:0035675 neuromast hair cell development Added TERM neuromast hair cell development
2011-02-15 GO:0035676 anterior lateral line neuromast hair cell development Added TERM anterior lateral line neuromast hair cell development
2011-02-15 GO:0035677 posterior lateral line neuromast hair cell development Added TERM posterior lateral line neuromast hair cell development
2011-02-15 GO:0035678 neuromast hair cell morphogenesis Added TERM neuromast hair cell morphogenesis
2011-02-15 GO:0035679 anterior lateral line neuromast hair cell morphogenesis Added TERM anterior lateral line neuromast hair cell morphogenesis
2011-02-15 GO:0035680 posterior lateral line neuromast hair cell morphogenesis Added TERM posterior lateral line neuromast hair cell morphogenesis
2011-02-15 GO:0043222 SMC/kleisin ring complex Deleted TERM SMC/kleisin ring complex
2011-02-15 GO:0044179 hemolysis in other organism Updated TERM hemolysis in other organism
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Updated TERM androstan-3-alpha,17-beta-diol dehydrogenase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Updated TERM 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity
2011-02-15 GO:0044402 competition with other organism Updated TERM competition with other organism
2011-02-15 GO:0051801 cytolysis in other organism involved in symbiotic interaction Updated TERM cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051802 regulation of cytolysis in other organism involved in symbiotic interaction Updated TERM regulation of cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051803 negative regulation of cytolysis in other organism involved in symbiotic interaction Updated TERM negative regulation of cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051804 positive regulation of cytolysis in other organism involved in symbiotic interaction Updated TERM positive regulation of cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051671 induction of autolysin activity in other organism Updated TERM induction of autolysin activity in other organism
2011-02-15 GO:0051673 membrane disruption in other organism Updated TERM membrane disruption in other organism
2011-02-15 GO:0051709 regulation of killing of cells of other organism Updated TERM regulation of killing of cells of other organism
2011-02-15 GO:0051710 regulation of cytolysis in other organism Updated TERM regulation of cytolysis in other organism
2011-02-15 GO:0051711 negative regulation of killing of cells of other organism Updated TERM negative regulation of killing of cells of other organism
2011-02-15 GO:0051712 positive regulation of killing of cells of other organism Updated TERM positive regulation of killing of cells of other organism
2011-02-15 GO:0051713 negative regulation of cytolysis in other organism Updated TERM negative regulation of cytolysis in other organism
2011-02-15 GO:0051714 positive regulation of cytolysis in other organism Updated TERM positive regulation of cytolysis in other organism
2011-02-15 GO:0051715 cytolysis in other organism Updated TERM cytolysis in other organism
2011-02-15 GO:0051287 NAD binding Updated TERM NAD+ or NADH binding
2011-02-15 GO:0050661 NADP binding Updated TERM NADP+ or NADPH binding
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Updated TERM 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
2011-02-15 GO:0047007 pregnan-21-ol dehydrogenase (NAD+) activity Updated TERM pregnan-21-ol dehydrogenase (NAD+) activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Updated TERM pregnan-21-ol dehydrogenase (NADP+) activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Updated TERM cholate 12-alpha dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Updated TERM androsterone dehydrogenase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Updated TERM 5alpha-androstane-3beta,17beta-diol dehydrogenase activity
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Updated TERM androsterone dehydrogenase (A-specific) activity
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Updated TERM testosterone dehydrogenase (NAD+) activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Updated TERM androsterone dehydrogenase (B-specific) activity
2011-02-15 GO:0052331 hemolysis in other organism involved in symbiotic interaction Updated TERM hemolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Updated TERM positive regulation of prostaglandin-endoperoxide synthase activity
2011-02-15 GO:0071407 cellular response to organic cyclic compound Updated TERM cellular response to organic cyclic compound
2011-02-15 GO:0070401 NADP+ binding Updated TERM NADP+ binding
2011-02-15 GO:0070403 NAD+ binding Updated TERM NAD+ binding
2011-02-15 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding Added TERM RNA polymerase I regulatory region sequence-specific DNA binding
2011-02-15 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding Added TERM RNA polymerase I core promoter sequence-specific DNA binding
2011-02-15 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding Added TERM RNA polymerase I upstream control element sequence-specific DNA binding
2011-02-15 GO:0001166 RNA polymerase I enhancer sequence-specific DNA binding Added TERM RNA polymerase I enhancer sequence-specific DNA binding
2011-02-15 GO:0001167 RNA polymerase I transcription factor activity, sequence-specific DNA binding Added TERM sequence-specific DNA binding RNA polymerase I transcription factor activity
2011-02-15 GO:0001168 transcription factor activity, RNA polymerase I upstream control element sequence-specific binding Added TERM RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity
2011-02-15 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding Added TERM RNA polymerase I core promoter sequence-specific DNA binding transcription factor activity
2011-02-15 GO:0001170 transcription factor activity, RNA polymerase I enhancer sequence-specific binding Added TERM RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Updated TERM sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Updated TERM cholate 7-alpha-dehydrogenase activity
2011-02-15 GO:0015892 siderophore-iron transport Deleted TERM siderophore-iron transport
2011-02-15 GO:0015343 siderophore transmembrane transporter activity Updated TERM siderophore transmembrane transporter activity
2011-02-15 GO:0015344 siderophore uptake transmembrane transporter activity Updated TERM siderophore uptake transmembrane transporter activity
2011-02-15 GO:0014070 response to organic cyclic compound Updated TERM response to organic cyclic compound
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Updated TERM testosterone dehydrogenase activity
2011-02-15 GO:0031640 killing of cells of other organism Updated TERM killing of cells of other organism
2011-02-15 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway Added TERM MyD88-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035661 MyD88-dependent toll-like receptor 2 signaling pathway Added TERM MyD88-dependent toll-like receptor 2 signaling pathway
2011-02-15 GO:0035662 Toll-like receptor 4 binding Added TERM Toll-like receptor 4 binding
2011-02-15 GO:0035663 Toll-like receptor 2 binding Added TERM Toll-like receptor 2 binding
2011-02-15 GO:0035664 TIRAP-dependent toll-like receptor signaling pathway Added TERM TIRAP-dependent toll-like receptor signaling pathway
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added TERM TIRAP-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added TERM TRIF-dependent toll-like receptor signaling pathway
2011-02-15 GO:0035667 TRIF-dependent toll-like receptor 4 signaling pathway Added TERM TRIF-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added TERM TRAM-dependent toll-like receptor signaling pathway
2011-02-15 GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway Added TERM TRAM-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035670 plant-type ovary development Added TERM ovule-producing ovary development
2011-02-15 GO:0035671 enone reductase activity Added TERM enone reductase activity
2011-02-15 GO:0035672 oligopeptide transmembrane transport Added TERM oligopeptide transmembrane transport
2011-02-15 GO:0035673 oligopeptide transmembrane transporter activity Added TERM oligopeptide transmembrane transporter activity
2011-02-15 GO:2000375 negative regulation of oxygen metabolic process Added TERM negative regulation of oxygen metabolic process
2011-02-15 GO:2000376 positive regulation of oxygen metabolic process Added TERM positive regulation of oxygen metabolic process
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added TERM regulation of reactive oxygen species metabolic process
2011-02-15 GO:2000378 negative regulation of reactive oxygen species metabolic process Added TERM negative regulation of reactive oxygen species metabolic process
2011-02-15 GO:2000379 positive regulation of reactive oxygen species metabolic process Added TERM positive regulation of reactive oxygen species metabolic process
2011-02-15 GO:2000332 regulation of blood microparticle formation Added TERM regulation of blood microparticle formation
2011-02-15 GO:2000333 negative regulation of blood microparticle formation Added TERM negative regulation of blood microparticle formation
2011-02-15 GO:2000334 positive regulation of blood microparticle formation Added TERM positive regulation of blood microparticle formation
2011-02-15 GO:2000335 regulation of endothelial microparticle formation Added TERM regulation of endothelial microparticle formation
2011-02-15 GO:2000336 negative regulation of endothelial microparticle formation Added TERM negative regulation of endothelial microparticle formation
2011-02-15 GO:2000337 positive regulation of endothelial microparticle formation Added TERM positive regulation of endothelial microparticle formation
2011-02-15 GO:2000338 regulation of chemokine (C-X-C motif) ligand 1 production Added TERM regulation of chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:2000339 negative regulation of chemokine (C-X-C motif) ligand 1 production Added TERM negative regulation of chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production Added TERM positive regulation of chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:0061385 fibroblast proliferation involved in heart morphogenesis Added TERM fibroblast proliferation involved in heart morphogenesis
2011-02-15 GO:0072580 bacterial-type EF-P lysine modification Added TERM bacterial-type EF-P lysine modification
2011-02-15 GO:0072581 protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine Added TERM protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine
2011-02-15 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity Added TERM 17-beta-hydroxysteroid dehydrogenase (NADP+) activity
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added TERM clathrin-mediated endocytosis
2011-02-15 GO:0072584 caveolin-mediated endocytosis Added TERM caveolin-mediated endocytosis
2011-02-15 GO:0072585 xanthosine nucleotidase activity Added TERM xanthosine nucleotidase activity
2011-02-15 GO:0072566 chemokine (C-X-C motif) ligand 1 production Added TERM chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:0072567 chemokine (C-X-C motif) ligand 2 production Added TERM chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:0072568 protein kinase C delta binding Added TERM protein kinase C delta binding
2011-02-15 GO:0072569 protein kinase C eta binding Added TERM protein kinase C eta binding
2011-02-15 GO:0072570 ADP-D-ribose binding Added TERM ADP-D-ribose binding
2011-02-15 GO:0072571 mono-ADP-D-ribose binding Added TERM mono-ADP-D-ribose binding
2011-02-15 GO:0072572 poly-ADP-D-ribose binding Added TERM poly-ADP-D-ribose binding
2011-02-15 GO:0072573 tolerance induction to lipopolysaccharide Added TERM tolerance induction to lipopolysaccharide
2011-02-15 GO:0072574 hepatocyte proliferation Added TERM hepatocyte proliferation
2011-02-15 GO:0072575 epithelial cell proliferation involved in liver morphogenesis Added TERM epithelial cell proliferation involved in liver morphogenesis
2011-02-15 GO:0072576 liver morphogenesis Added TERM liver morphogenesis
2011-02-15 GO:0072577 endothelial cell apoptotic process Added TERM endothelial cell apoptosis
2011-02-15 GO:0072578 neurotransmitter-gated ion channel clustering Added TERM neurotransmitter-gated ion channel clustering
2011-02-15 GO:0072579 glycine receptor clustering Added TERM glycine receptor clustering
2011-02-15 GO:0072586 DNA topoisomerase (ATP-hydrolyzing) regulator activity Added TERM DNA topoisomerase (ATP-hydrolyzing) regulator activity
2011-02-15 GO:0072587 DNA topoisomerase (ATP-hydrolyzing) activator activity Added TERM DNA topoisomerase (ATP-hydrolyzing) activator activity
2011-02-15 GO:0072588 box H/ACA RNP complex Added TERM box H/ACA RNP complex
2011-02-15 GO:0072589 box H/ACA scaRNP complex Added TERM box H/ACA scaRNP complex
2011-02-15 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity Added TERM N-acetyl-L-aspartate-L-glutamate ligase activity
2011-02-15 GO:0072591 citrate-L-glutamate ligase activity Added TERM citrate-L-glutamate ligase activity
2011-02-15 GO:0072592 oxygen metabolic process Added TERM oxygen metabolic process
2011-02-15 GO:0072593 reactive oxygen species metabolic process Added TERM reactive oxygen species metabolic process
2011-02-15 GO:0072594 establishment of protein localization to organelle Added TERM establishment of protein localization to organelle
2011-02-15 GO:0072595 maintenance of protein localization in organelle Added TERM maintenance of protein localization to organelle
2011-02-15 GO:0072596 establishment of protein localization to chloroplast Added TERM establishment of protein localization to chloroplast
2011-02-15 GO:0072597 maintenance of protein location in chloroplast Added TERM maintenance of protein location in chloroplast
2011-02-15 GO:0072598 protein localization to chloroplast Added TERM protein localization to chloroplast
2011-02-15 GO:0072599 establishment of protein localization to endoplasmic reticulum Added TERM establishment of protein localization in endoplasmic reticulum
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added TERM establishment of protein localization in Golgi
2011-02-15 GO:0072655 establishment of protein localization to mitochondrion Added TERM establishment of protein localization in mitochondrion
2011-02-15 GO:0072656 maintenance of protein location in mitochondrion Added TERM maintenance of protein location in mitochondrion
2011-02-15 GO:0072657 protein localization to membrane Added TERM protein localization in membrane
2011-02-15 GO:0072658 maintenance of protein location in membrane Added TERM maintenance of protein location in membrane
2011-02-15 GO:0072659 protein localization to plasma membrane Added TERM protein localization in plasma membrane
2011-02-15 GO:0072660 maintenance of protein location in plasma membrane Added TERM maintenance of protein location in plasma membrane
2011-02-15 GO:0072661 protein targeting to plasma membrane Added TERM protein targeting to plasma membrane
2011-02-15 GO:0072662 protein localization to peroxisome Added TERM protein localization to peroxisome
2011-02-15 GO:0072663 establishment of protein localization to peroxisome Added TERM establishment of protein localization to peroxisome
2011-02-15 GO:0072664 maintenance of protein location in peroxisome Added TERM maintenance of protein location in peroxisome
2011-02-15 GO:0072665 protein localization to vacuole Added TERM protein localization to vacuole
2011-02-15 GO:0072666 establishment of protein localization to vacuole Added TERM establishment of protein localization to vacuole
2011-02-15 GO:0072667 maintenance of protein location in vacuole Added TERM maintenance of protein location in vacuole
2011-02-15 GO:0072668 obsolete tubulin complex biogenesis Added TERM tubulin complex biogenesis
2011-02-15 GO:0043222 SMC/kleisin ring complex Deleted DEFINITION A molecular ring complex composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1 and Smc3, and the kleisin protein Scc1.
2011-02-15 GO:0072557 IPAF inflammasome complex Deleted DEFINITION A protein complex that consists of four components, NALP1, PYCARD (ASC)(27), caspase-1 and caspase-5 and includes among its functions that of being the primary mediator of susceptibility to anthrax lethal toxin.
2011-02-15 GO:0042128 nitrate assimilation Deleted DEFINITION The uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.
2011-02-15 GO:0071915 protein-lysine lysylation Deleted DEFINITION The addition of lysine to a lysine residue in a protein, producing N6-(lysyl)lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
2011-02-15 GO:0072558 NLRP1 inflammasome complex Deleted DEFINITION A protein complex that consists of three components, NALP3, PYCARD and caspase-1 and includes among its functions the sensing of various stimuli including anti-viral compounds R837 and R848, bacterial mRNA, gout-associated crystals, bacterial toxins derived from Listeria M., staphylococcus A. and shigella F.
2011-02-15 GO:0031429 box H/ACA snoRNP complex Deleted DEFINITION A ribonucleoprotein complex containing small nucleolar RNA of the box H/ACA type.
2011-02-15 GO:0005183 gonadotropin hormone-releasing hormone activity Deleted DEFINITION The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, GnRH causes the release of follicle-stimulating hormone and luteinizing hormone by the anterior pituitary.
2011-02-15 GO:0071407 cellular response to organic cyclic compound Deleted DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic substance stimulus.
2011-02-15 GO:0016362 activin receptor activity, type II Deleted DEFINITION Combining with activin to initiate a change in cell activity; upon ligand binding, binds to catalyzes the phosphorylation of type I activin receptor.
2011-02-15 GO:0002755 MyD88-dependent toll-like receptor signaling pathway Deleted DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor and relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0014070 response to organic cyclic compound Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic substance stimulus.
2011-02-15 GO:0008278 cohesin complex Deleted DEFINITION A protein complex required for sister chromatid cohesion in eukaryotes.
2011-02-15 GO:0050661 NADP binding Deleted DEFINITION Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP, or the reduced form, NADPH.
2011-02-15 GO:0005025 transforming growth factor beta receptor activity, type I Deleted DEFINITION Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity.
2011-02-15 GO:0072559 NLRP3 inflammasome complex Deleted DEFINITION A protein complex that consists of three components, IPAF, NAIP and caspase-1 and includes among its functions the sensing of flagellin derived from Legionella P., Salmonella T., pseudomonas A. and shigella F.
2011-02-15 GO:0048903 anterior lateral line neuromast hair cell differentiation Deleted DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2011-02-15 GO:0070401 NADP+ binding Deleted DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity Deleted DEFINITION Any process that modulates the rate, frequency or extent of prostaglandin-endoperoxidase activity. Prostaglandin-endoperoxidase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity Deleted DEFINITION Catalysis of the reaction: 3-beta-hydroxy-delta(5)-steroid + NAD+ = 3-oxo-delta(5)-steroid + NADH + H+.
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Deleted DEFINITION Any process that increases the rate, frequency or extent of prostaglandin-endoperoxidase activity. Prostaglandin-endoperoxidase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0031428 box C/D snoRNP complex Deleted DEFINITION A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type.
2011-02-15 GO:0051287 NAD binding Deleted DEFINITION Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD, or the reduced form, NADH.
2011-02-15 GO:0044402 competition with other organism Deleted DEFINITION Any process in which an organism within a multispecies research community gains an advantage in growth or survival over another organism of a different species in that research community.
2011-02-15 GO:0009341 beta-galactosidase complex Deleted DEFINITION A multimeric enzyme complex that in E. coli is a heterooctamer made up of four alpha subunits and four beta subunits. Catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.
2011-02-15 GO:0005732 small nucleolar ribonucleoprotein complex Deleted DEFINITION A ribonucleoprotein complex that contains a small nucleolar RNA (snoRNA) and associated proteins, and is found in eukaryotic cells. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2011-02-15 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding Deleted DEFINITION Interacting selectively and non-covalently with a RNA polymerase II (Pol II) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2011-02-15 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production Added TERM regulation of chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production Added TERM negative regulation of chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production Added TERM positive regulation of chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:2000344 positive regulation of acrosome reaction Added TERM positive regulation of acrosome reaction
2011-02-15 GO:2000345 regulation of hepatocyte proliferation Added TERM regulation of hepatocyte proliferation
2011-02-15 GO:2000346 negative regulation of hepatocyte proliferation Added TERM negative regulation of hepatocyte proliferation
2011-02-15 GO:2000347 positive regulation of hepatocyte proliferation Added TERM positive regulation of hepatocyte proliferation
2011-02-15 GO:2000348 regulation of CD40 signaling pathway Added TERM regulation of CD40 signaling pathway
2011-02-15 GO:2000349 negative regulation of CD40 signaling pathway Added TERM negative regulation of CD40 signaling pathway
2011-02-15 GO:2000350 positive regulation of CD40 signaling pathway Added TERM positive regulation of CD40 signaling pathway
2011-02-15 GO:2000351 regulation of endothelial cell apoptotic process Added TERM regulation of endothelial cell apoptosis
2011-02-15 GO:2000352 negative regulation of endothelial cell apoptotic process Added TERM negative regulation of endothelial cell apoptosis
2011-02-15 GO:2000353 positive regulation of endothelial cell apoptotic process Added TERM positive regulation of endothelial cell apoptosis
2011-02-15 GO:2000354 regulation of ovarian follicle development Added TERM regulation of ovarian follicle development
2011-02-15 GO:2000355 negative regulation of ovarian follicle development Added TERM negative regulation of ovarian follicle development
2011-02-15 GO:2000356 regulation of kidney smooth muscle cell differentiation Added TERM regulation of kidney smooth muscle cell differentiation
2011-02-15 GO:2000357 negative regulation of kidney smooth muscle cell differentiation Added TERM negative regulation of kidney smooth muscle cell differentiation
2011-02-15 GO:2000358 positive regulation of kidney smooth muscle cell differentiation Added TERM positive regulation of kidney smooth muscle cell differentiation
2011-02-15 GO:2000359 regulation of binding of sperm to zona pellucida Added TERM regulation of binding of sperm to zona pellucida
2011-02-15 GO:2000360 negative regulation of binding of sperm to zona pellucida Added TERM negative regulation of binding of sperm to zona pellucida
2011-02-15 GO:2000361 regulation of prostaglandin-E synthase activity Added TERM regulation of prostaglandin-E synthase activity
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added TERM negative regulation of prostaglandin-E synthase activity
2011-02-15 GO:2000363 positive regulation of prostaglandin-E synthase activity Added TERM positive regulation of prostaglandin-E synthase activity
2011-02-15 GO:2000364 regulation of STAT protein import into nucleus Added TERM regulation of STAT protein import into nucleus
2011-02-15 GO:2000365 negative regulation of STAT protein import into nucleus Added TERM negative regulation of STAT protein import into nucleus
2011-02-15 GO:2000366 positive regulation of STAT protein import into nucleus Added TERM positive regulation of STAT protein import into nucleus
2011-02-15 GO:2000367 regulation of acrosomal vesicle exocytosis Added TERM regulation of acrosomal vesicle exocytosis
2011-02-15 GO:2000368 positive regulation of acrosomal vesicle exocytosis Added TERM positive regulation of acrosomal vesicle exocytosis
2011-02-15 GO:2000369 regulation of clathrin-mediated endocytosis Added TERM regulation of clathrin-mediated endocytosis
2011-02-15 GO:2000370 positive regulation of clathrin-mediated endocytosis Added TERM positive regulation of clathrin-mediated endocytosis
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added TERM regulation of DNA topoisomerase (ATP-hydrolyzing) activity
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added TERM negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added TERM positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
2011-02-15 GO:2000374 regulation of oxygen metabolic process Added TERM regulation of oxygen metabolic process
2011-02-15 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the core element.
2011-02-15 GO:0001167 RNA polymerase I transcription factor activity, sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
2011-02-15 GO:0001168 transcription factor activity, RNA polymerase I upstream control element sequence-specific binding Added DEFINITION Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I.
2011-02-15 GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity Deleted DEFINITION Catalysis of the reaction: NADP+ + 7-beta-hydroxysteroid = NADPH + H+ + 7-oxosteroid.
2011-02-15 GO:0043113 receptor clustering Deleted DEFINITION Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
2011-02-15 GO:0014070 response to organic cyclic compound Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2011-02-15 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0035662 Toll-like receptor 4 binding Added DEFINITION Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0072558 NLRP1 inflammasome complex Added DEFINITION A protein complex that consists of three components, NALP3, PYCARD and caspase-1, and includes among its functions the sensing of various stimuli including anti-viral compounds R837 and R848, bacterial mRNA, gout-associated crystals, bacterial toxins derived from Listeria monocytogenes, Staphylococcus aureus and Shigella flexneri.
2011-02-15 GO:0072569 protein kinase C eta binding Added DEFINITION Interacting selectively and non-covalently with protein kinase C eta.
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added DEFINITION An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
2011-02-15 GO:0072585 xanthosine nucleotidase activity Added DEFINITION Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
2011-02-15 GO:0072594 establishment of protein localization to organelle Added DEFINITION The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
2011-02-15 GO:0072595 maintenance of protein localization in organelle Added DEFINITION Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
2011-02-15 GO:0072659 protein localization to plasma membrane Added DEFINITION A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
2011-02-15 GO:0072664 maintenance of protein location in peroxisome Added DEFINITION Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.
2011-02-15 GO:2000336 negative regulation of endothelial microparticle formation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation.
2011-02-15 GO:2000347 positive regulation of hepatocyte proliferation Added DEFINITION Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
2011-02-15 GO:2000356 regulation of kidney smooth muscle cell differentiation Added DEFINITION Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation.
2011-02-15 GO:2000370 positive regulation of clathrin-mediated endocytosis Added DEFINITION Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
2011-02-15 GO:2000376 positive regulation of oxygen metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.
2011-02-15 GO:0008278 cohesin complex Added DEFINITION A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
2011-02-15 GO:0016362 activin receptor activity, type II Added DEFINITION Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0035678 neuromast hair cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
2011-02-15 GO:0042128 nitrate assimilation Added DEFINITION The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.
2011-02-15 GO:0070401 NADP+ binding Added DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 GO:0072559 NLRP3 inflammasome complex Added DEFINITION A protein complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.
2011-02-15 GO:0072567 chemokine (C-X-C motif) ligand 2 production Added DEFINITION The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2011-02-15 GO:0072574 hepatocyte proliferation Added DEFINITION The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.
2011-02-15 GO:0072580 bacterial-type EF-P lysine modification Added DEFINITION The modification of a lysine residue in a protein, producing (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).
2011-02-15 GO:0072587 DNA topoisomerase (ATP-hydrolyzing) activator activity Added DEFINITION Increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
2011-02-15 GO:0072668 obsolete tubulin complex biogenesis Added DEFINITION A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled.
2011-02-15 GO:2000332 regulation of blood microparticle formation Added DEFINITION Any process that modulates the frequency, rate or extent of blood microparticle formation.
2011-02-15 GO:2000333 negative regulation of blood microparticle formation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.
2011-02-15 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2011-02-15 GO:2000345 regulation of hepatocyte proliferation Added DEFINITION Any process that modulates the frequency, rate or extent of hepatocyte proliferation.
2011-02-15 GO:2000346 negative regulation of hepatocyte proliferation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.
2011-02-15 GO:2000352 negative regulation of endothelial cell apoptotic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptosis.
2011-02-15 GO:2000353 positive regulation of endothelial cell apoptotic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of endothelial cell apoptosis.
2011-02-15 GO:2000354 regulation of ovarian follicle development Added DEFINITION Any process that modulates the frequency, rate or extent of ovarian follicle development.
2011-02-15 GO:2000375 negative regulation of oxygen metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.
2011-02-15 GO:0035677 posterior lateral line neuromast hair cell development Added DEFINITION The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
2011-02-15 GO:0035679 anterior lateral line neuromast hair cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
2011-02-15 GO:0035680 posterior lateral line neuromast hair cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
2011-02-15 GO:0043113 receptor clustering Added DEFINITION The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
2011-02-15 GO:0061385 fibroblast proliferation involved in heart morphogenesis Added DEFINITION The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.
2011-02-15 GO:0071915 protein-lysine lysylation Added DEFINITION The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
2011-02-15 GO:0072542 protein phosphatase activator activity Added DEFINITION Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
2011-02-15 GO:0072572 poly-ADP-D-ribose binding Added DEFINITION Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.
2011-02-15 GO:0072573 tolerance induction to lipopolysaccharide Added DEFINITION Tolerance induction directed at lipopolysaccharide antigens.
2011-02-15 GO:0072575 epithelial cell proliferation involved in liver morphogenesis Added DEFINITION The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.
2011-02-15 GO:0072577 endothelial cell apoptotic process Added DEFINITION The process of apoptosis in endothelial cells. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
2011-02-15 GO:0072579 glycine receptor clustering Added DEFINITION The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.
2011-02-15 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity Added DEFINITION Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added DEFINITION The directed movement of a protein to a specific location in the Golgi apparatus.
2011-02-15 GO:0072660 maintenance of protein location in plasma membrane Added DEFINITION Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.
2011-02-15 GO:0072662 protein localization to peroxisome Added DEFINITION A process in which a protein is transported to, or maintained at, a location in a peroxisome.
2011-02-15 GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production Added DEFINITION Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2011-02-15 GO:2000344 positive regulation of acrosome reaction Added DEFINITION Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
2011-02-15 GO:2000348 regulation of CD40 signaling pathway Added DEFINITION Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.
2011-02-15 GO:0015892 siderophore-iron transport Deleted DEFINITION The directed movement of iron-siderophores into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Iron-siderophores are low molecular weight Fe(III)-chelating substances in the iron-bound form.
2011-02-15 GO:2000366 positive regulation of STAT protein import into nucleus Added DEFINITION Any process that activates or increases the frequency, rate or extent of STAT protein import into nucleus.
2011-02-15 GO:2000358 positive regulation of kidney smooth muscle cell differentiation Added DEFINITION Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation.
2011-02-15 GO:2000363 positive regulation of prostaglandin-E synthase activity Added DEFINITION Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.
2011-02-15 GO:2000351 regulation of endothelial cell apoptotic process Added DEFINITION Any process that modulates the frequency, rate or extent of endothelial cell apoptosis.
2011-02-15 GO:2000359 regulation of binding of sperm to zona pellucida Added DEFINITION Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida.
2011-02-15 GO:2000360 negative regulation of binding of sperm to zona pellucida Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.
2011-02-15 GO:2000361 regulation of prostaglandin-E synthase activity Added DEFINITION Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity.
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added DEFINITION Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2011-02-15 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding Added DEFINITION Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I.
2011-02-15 GO:0001170 transcription factor activity, RNA polymerase I enhancer sequence-specific binding Added DEFINITION Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I.
2011-02-15 GO:0005025 transforming growth factor beta receptor activity, type I Added DEFINITION Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.
2011-02-15 GO:0005732 small nucleolar ribonucleoprotein complex Added DEFINITION A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2011-02-15 GO:0035671 enone reductase activity Added DEFINITION Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.
2011-02-15 GO:0035672 oligopeptide transmembrane transport Added DEFINITION The directed movement of an oligopeptide across a membrane by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
2011-02-15 GO:0035673 oligopeptide transmembrane transporter activity Added DEFINITION Catalysis of the transfer of oligopeptides from one side of the membrane to the other.
2011-02-15 GO:0044402 competition with other organism Added DEFINITION Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community.
2011-02-15 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity Added DEFINITION Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0072491 toluene-containing compound catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.
2011-02-15 GO:0072557 IPAF inflammasome complex Added DEFINITION A protein complex that consists of four components, NALP1, PYCARD (ASC)(27), caspase-1 and caspase-5, and includes among its functions that of being the primary mediator of susceptibility to anthrax lethal toxin.
2011-02-15 GO:0072566 chemokine (C-X-C motif) ligand 1 production Added DEFINITION The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2011-02-15 GO:0072568 protein kinase C delta binding Added DEFINITION Interacting selectively and non-covalently with protein kinase C delta.
2011-02-15 GO:0072576 liver morphogenesis Added DEFINITION The process in which the anatomical structures of the liver are generated and organized.
2011-02-15 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.
2011-02-15 GO:0072586 DNA topoisomerase (ATP-hydrolyzing) regulator activity Added DEFINITION Modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
2011-02-15 GO:0072588 box H/ACA RNP complex Added DEFINITION A ribonucleoprotein complex that contains an RNA of the box H/ACA type, a subtype of the small nucleolar RNA (snoRNA) family. RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs, although some have evolved other functions. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and on U2 small nuclear RNA (U2 snRNA).
2011-02-15 GO:0072597 maintenance of protein location in chloroplast Added DEFINITION Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere.
2011-02-15 GO:0072655 establishment of protein localization to mitochondrion Added DEFINITION The directed movement of a protein to a specific location in the mitochondrion.
2011-02-15 GO:0072665 protein localization to vacuole Added DEFINITION A process in which a protein is transported to, or maintained at, a location in a vacuole.
2011-02-15 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production Added DEFINITION Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2011-02-15 GO:2000349 negative regulation of CD40 signaling pathway Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity.
2011-02-15 GO:2000367 regulation of acrosomal vesicle exocytosis Added DEFINITION Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis.
2011-02-15 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a RNA polymerase II (Pol II) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2011-02-15 GO:0005183 gonadotropin hormone-releasing hormone activity Added DEFINITION The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary.
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0048903 anterior lateral line neuromast hair cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2011-02-15 GO:0050661 NADP binding Added DEFINITION Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
2011-02-15 GO:0051287 NAD binding Added DEFINITION Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
2011-02-15 GO:0072570 ADP-D-ribose binding Added DEFINITION Interacting selectively and non-covalently with ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
2011-02-15 GO:0072578 neurotransmitter-gated ion channel clustering Added DEFINITION The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.
2011-02-15 GO:0072584 caveolin-mediated endocytosis Added DEFINITION An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.
2011-02-15 GO:0072592 oxygen metabolic process Added DEFINITION The chemical reactions and pathways involving diatomic oxygen (O2).
2011-02-15 GO:0072598 protein localization to chloroplast Added DEFINITION A process in which a protein is transported to, or maintained at, a location in a chloroplast.
2011-02-15 GO:0072661 protein targeting to plasma membrane Added DEFINITION The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
2011-02-15 GO:0072663 establishment of protein localization to peroxisome Added DEFINITION The directed movement of a protein to a specific location in a peroxisome.
2011-02-15 GO:2000339 negative regulation of chemokine (C-X-C motif) ligand 1 production Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2011-02-15 GO:2000369 regulation of clathrin-mediated endocytosis Added DEFINITION Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added DEFINITION Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2011-02-15 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.
2011-02-15 GO:0001166 RNA polymerase I enhancer sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2011-02-15 GO:0035663 Toll-like receptor 2 binding Added DEFINITION Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.
2011-02-15 GO:0035664 TIRAP-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0035670 plant-type ovary development Added DEFINITION The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.
2011-02-15 GO:0035674 tricarboxylic acid transmembrane transport Added DEFINITION The process in which tricarboxylic acids are transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2011-02-15 GO:0035676 anterior lateral line neuromast hair cell development Added DEFINITION The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
2011-02-15 GO:0072571 mono-ADP-D-ribose binding Added DEFINITION Interacting selectively and non-covalently with monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
2011-02-15 GO:0072589 box H/ACA scaRNP complex Added DEFINITION A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.
2011-02-15 GO:0072591 citrate-L-glutamate ligase activity Added DEFINITION Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.
2011-02-15 GO:0072657 protein localization to membrane Added DEFINITION A process in which a protein is transported to, or maintained in, a specific location in a membrane.
2011-02-15 GO:0072666 establishment of protein localization to vacuole Added DEFINITION The directed movement of a protein to a specific location in a vacuole.
2011-02-15 GO:2000357 negative regulation of kidney smooth muscle cell differentiation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation.
2011-02-15 GO:2000364 regulation of STAT protein import into nucleus Added DEFINITION Any process that modulates the frequency, rate or extent of STAT protein import into nucleus.
2011-02-15 GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production Added SYNONYM positive regulation of SCYB1 production
2011-02-15 GO:2000361 regulation of prostaglandin-E synthase activity Added SYNONYM regulation of PGE2 isomerase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Added SYNONYM glycerone transferase activity
2011-02-15 GO:0014070 response to organic cyclic compound Added SYNONYM response to organic cyclic substance
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM positive regulation of topoisomerase
2011-02-15 GO:0072584 caveolin-mediated endocytosis Added SYNONYM caveolae-mediated endocytosis
2011-02-15 GO:2000337 positive regulation of endothelial microparticle formation Added SYNONYM positive regulation of endothelial microparticle generation
2011-02-15 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM regulation of PG synthetase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Added SYNONYM 3beta,20alpha-hydroxysteroid oxidoreductase activity
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM regulation of type II DNA topoisomerase activity
2011-02-15 GO:0060043 regulation of cardiac muscle cell proliferation Added SYNONYM regulation of cardiomyocyte proliferation
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added SYNONYM regulation of ROS metabolic process
2011-02-15 GO:0072572 poly-ADP-D-ribose binding Added SYNONYM pADPr binding
2011-02-15 GO:0072571 mono-ADP-D-ribose binding Added SYNONYM mADPr binding
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Added SYNONYM 12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
2011-02-15 GO:0035662 Toll-like receptor 4 binding Added SYNONYM TLR4 binding
2011-02-15 GO:0072589 box H/ACA scaRNP complex Added SYNONYM nucleoplasmic box H/ACA RNP pseudouridylase complex
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added SYNONYM negative regulation of PGE2 isomerase activity
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added SYNONYM TRAM-dependent toll-like receptor signalling pathway
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM positive regulation of PG synthetase activity
2011-02-15 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding Added SYNONYM RNA polymerase I core element sequence-specific DNA binding
2011-02-15 GO:0051713 negative regulation of cytolysis in other organism Added SYNONYM negative regulation of cytolysis of cells of another organism
2011-02-15 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production Added SYNONYM negative regulation of MIP2 production
2011-02-15 GO:2000375 negative regulation of oxygen metabolic process Added SYNONYM negative regulation of oxygen metabolism
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Added SYNONYM 3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0015892 siderophore-iron transport Deleted SYNONYM iron-siderochrome transport
2011-02-15 GO:0015892 siderophore-iron transport Deleted SYNONYM iron-siderophore transport
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Deleted SYNONYM 7alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Deleted SYNONYM 3(or 17)alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Deleted SYNONYM 3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3beta(or 20alpha)-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3beta,20alpha-hydroxysteroid oxidoreductase activity
2011-02-15 GO:0009341 beta-galactosidase complex Added DEFINITION A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.
2011-02-15 GO:0031428 box C/D snoRNP complex Added DEFINITION A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs.
2011-02-15 GO:0031429 box H/ACA snoRNP complex Added DEFINITION A box H/ACA RNP complex that is located in the nucleolus.
2011-02-15 GO:0035661 MyD88-dependent toll-like receptor 2 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.
2011-02-15 GO:0072581 protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine Added DEFINITION The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
2011-02-15 GO:0072593 reactive oxygen species metabolic process Added DEFINITION The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
2011-02-15 GO:0072656 maintenance of protein location in mitochondrion Added DEFINITION Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.
2011-02-15 GO:2000335 regulation of endothelial microparticle formation Added DEFINITION Any process that modulates the frequency, rate or extent of endothelial microparticle formation.
2011-02-15 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production Added DEFINITION Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2011-02-15 GO:2000355 negative regulation of ovarian follicle development Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
2011-02-15 GO:2000368 positive regulation of acrosomal vesicle exocytosis Added DEFINITION Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
2011-02-15 GO:2000374 regulation of oxygen metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of oxygen metabolic process.
2011-02-15 GO:2000378 negative regulation of reactive oxygen species metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.
2011-02-15 GO:2000379 positive regulation of reactive oxygen species metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
2011-02-15 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I.
2011-02-15 GO:0002755 MyD88-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity Added DEFINITION Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H+.
2011-02-15 GO:0035667 TRIF-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0035675 neuromast hair cell development Added DEFINITION The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
2011-02-15 GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added DEFINITION Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0071407 cellular response to organic cyclic compound Added DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2011-02-15 GO:0072596 establishment of protein localization to chloroplast Added DEFINITION The directed movement of a protein to a specific location in a chloroplast.
2011-02-15 GO:0072599 establishment of protein localization to endoplasmic reticulum Added DEFINITION The directed movement of a protein to a specific location in the endoplasmic reticulum.
2011-02-15 GO:0072658 maintenance of protein location in membrane Added DEFINITION Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.
2011-02-15 GO:0072667 maintenance of protein location in vacuole Added DEFINITION Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.
2011-02-15 GO:2000334 positive regulation of blood microparticle formation Added DEFINITION Any process that activates or increases the frequency, rate or extent of blood microparticle formation.
2011-02-15 GO:2000337 positive regulation of endothelial microparticle formation Added DEFINITION Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation.
2011-02-15 GO:2000338 regulation of chemokine (C-X-C motif) ligand 1 production Added DEFINITION Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2011-02-15 GO:2000350 positive regulation of CD40 signaling pathway Added DEFINITION Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.
2011-02-15 GO:2000365 negative regulation of STAT protein import into nucleus Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of STAT protein import into nucleus.
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Added SYNONYM dehydrogenase, 3beta,20alpha-hydroxy steroid
2011-02-15 GO:0051710 regulation of cytolysis in other organism Added SYNONYM regulation of cytolysis of cells of another organism
2011-02-15 GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway Added SYNONYM TRAM-dependent toll-like receptor 4 signalling pathway
2011-02-15 GO:2000334 positive regulation of blood microparticle formation Added SYNONYM positive regulation of microparticle generation
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added SYNONYM negative regulation of prostaglandin endoperoxide E isomerase activity
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added SYNONYM regulation of reactive oxygen species metabolism
2011-02-15 GO:2000339 negative regulation of chemokine (C-X-C motif) ligand 1 production Added SYNONYM negative regulation of SCYB1 production
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM positive regulation of fatty acid cyclooxygenase activity
2011-02-15 GO:2000351 regulation of endothelial cell apoptotic process Added SYNONYM regulation of apoptosis of endothelial cells
2011-02-15 GO:2000352 negative regulation of endothelial cell apoptotic process Added SYNONYM negative regulation of programmed cell death of endothelial cells by apoptosis
2011-02-15 GO:0015891 siderophore transport Added SYNONYM siderophore-iron transport
2011-02-15 GO:0051801 cytolysis in other organism involved in symbiotic interaction Added SYNONYM cytolysis of cells in other organism involved in symbiotic interaction
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Added SYNONYM dihydroxyacetonetransferase activity
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Added SYNONYM 7-alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added SYNONYM clathrin-dependent endocytosis
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM regulation of DNA-gyrase activity
2011-02-15 GO:0042927 siderophore transporter activity Added SYNONYM siderophore-iron transporter activity
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Added SYNONYM 17beta-hydroxy steroid dehydrogenase
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of DNA-gyrase activity
2011-02-15 GO:2000335 regulation of endothelial microparticle formation Added SYNONYM regulation of endothelial microparticle generation
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of deoxyribonucleic topoisomerase activity
2011-02-15 GO:0072569 protein kinase C eta binding Added SYNONYM PRKCH binding
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Added SYNONYM 12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added SYNONYM TRIF-dependent toll-like receptor signalling pathway
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added SYNONYM negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added SYNONYM TIRAP-dependent toll-like receptor 4 signalling pathway
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM positive regulation of DNA topoisomerase IV activity
2011-02-15 GO:2000353 positive regulation of endothelial cell apoptotic process Added SYNONYM positive regulation of killing of endothelial cells
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM dehydrogenase, 3beta,20alpha-hydroxy steroid
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid dehydrogenase (A-specific)
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 17beta-hydroxy steroid dehydrogenase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 3beta-hydroxy steroid dehydrogenase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 3beta-hydroxysteroid dehydrogenase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM beta-hydroxy steroid dehydrogenase
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Deleted SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Deleted SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Deleted SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid dehydrogenase (B-specific)
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid oxidoreductase activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 20beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 3alpha(or 20beta)-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM NADH-20beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM dehydrogenase, 20beta-hydroxy steroid
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM delta4-3-ketosteroid hydrogenase activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM 21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM 21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM NADP-21-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3-beta-HSD activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM progesterone reductase activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3-alpha-HSD activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM (R)-20-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0072568 protein kinase C delta binding Added SYNONYM PRKCD binding
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Added SYNONYM NADH-20beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:2000336 negative regulation of endothelial microparticle formation Added SYNONYM negative regulation of endothelial microparticle release
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Added SYNONYM 3alpha-hydroxysteroid dehydrogenase (A-specific)
2011-02-15 GO:0072577 endothelial cell apoptotic process Added SYNONYM programmed cell death, endothelial cells
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added SYNONYM TRAM-dependent TLR signaling pathway
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added SYNONYM clathrin coated pit-dependent endocytosis
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added SYNONYM MyD88 adapter-like dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:2000354 regulation of ovarian follicle development Added SYNONYM regulation of follicular phase
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added SYNONYM establishment of protein localisation to Golgi
2011-02-15 GO:2000379 positive regulation of reactive oxygen species metabolic process Added SYNONYM positive regulation of reactive oxygen species metabolism
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Added SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 GO:0031429 box H/ACA snoRNP complex Added SYNONYM box H/ACA snoRNP pseudouridylase complex
2011-02-15 GO:2000349 negative regulation of CD40 signaling pathway Added SYNONYM negative regulation of CD40 signalling pathway
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Added SYNONYM 20alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM positive regulation of (PG)H synthase activity
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of topoisomerase II
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added SYNONYM establishment of protein localisation to Golgi apparatus
2011-02-15 GO:0031640 killing of cells of other organism Added SYNONYM killing of cells of another organism
2011-02-15 GO:0015344 siderophore uptake transmembrane transporter activity Added SYNONYM siderophore-iron uptake transmembrane transporter activity
2011-02-15 GO:0072596 establishment of protein localization to chloroplast Added SYNONYM establishment of protein localisation to chloroplast
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Added SYNONYM 12alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:2000367 regulation of acrosomal vesicle exocytosis Added SYNONYM regulation of acrosome exocytosis
2011-02-15 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production Added SYNONYM positive regulation of MIP2 production
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of DNA topoisomerase II
2011-02-15 GO:0051712 positive regulation of killing of cells of other organism Added SYNONYM positive regulation of killing of cells of other organism
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added SYNONYM TRIF-dependent TLR signaling pathway
2011-02-15 GO:0072577 endothelial cell apoptotic process Added SYNONYM killing of endothelial cells
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM regulation of topoisomerase
2011-02-15 GO:0071407 cellular response to organic cyclic compound Added SYNONYM cellular response to organic cyclic substance
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added SYNONYM TIRAP-dependent TLR4 signaling pathway
2011-02-15 GO:0035661 MyD88-dependent toll-like receptor 2 signaling pathway Added SYNONYM MyD88-dependent toll-like receptor 2 signalling pathway
2011-02-15 GO:0072577 endothelial cell apoptotic process Added SYNONYM apoptosis of endothelial cells
2011-02-15 GO:0051714 positive regulation of cytolysis in other organism Added SYNONYM positive regulation of cytolysis of cells of another organism
2011-02-15 GO:2000333 negative regulation of blood microparticle formation Added SYNONYM negative regulation of microparticle generation
2011-02-15 GO:2000368 positive regulation of acrosomal vesicle exocytosis Added SYNONYM positive regulation of acrosome exocytosis
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Deleted SYNONYM 7alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Deleted SYNONYM 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM dihydroxyacetonetransferase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Deleted SYNONYM 12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Deleted SYNONYM 12beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Deleted SYNONYM 12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Deleted SYNONYM 20alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Deleted SYNONYM 20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity
2011-02-15 GO:0047007 pregnan-21-ol dehydrogenase (NAD+) activity Deleted SYNONYM 21-hydroxysteroid:NAD+ 21-oxidoreductase activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM 21-hydroxysteroid:NADP+ 21-oxidoreductase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM 12alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM 12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM 12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM NADP-12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Deleted SYNONYM 3(17)alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM cortisone reductase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM dihydroxyacetone transferase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM glycerone transferase activity
2011-02-15 GO:2000360 negative regulation of binding of sperm to zona pellucida Added SYNONYM negative regulation of ZPG binding

Terms

Timestamp GO ID GO Term Name Action Category Detail
2011-02-15 GO:0035674 tricarboxylic acid transmembrane transport Added TERM tricarboxylic acid transmembrane transport
2011-02-15 GO:0035675 neuromast hair cell development Added TERM neuromast hair cell development
2011-02-15 GO:0035676 anterior lateral line neuromast hair cell development Added TERM anterior lateral line neuromast hair cell development
2011-02-15 GO:0035677 posterior lateral line neuromast hair cell development Added TERM posterior lateral line neuromast hair cell development
2011-02-15 GO:0035678 neuromast hair cell morphogenesis Added TERM neuromast hair cell morphogenesis
2011-02-15 GO:0035679 anterior lateral line neuromast hair cell morphogenesis Added TERM anterior lateral line neuromast hair cell morphogenesis
2011-02-15 GO:0035680 posterior lateral line neuromast hair cell morphogenesis Added TERM posterior lateral line neuromast hair cell morphogenesis
2011-02-15 GO:0043222 SMC/kleisin ring complex Deleted TERM SMC/kleisin ring complex
2011-02-15 GO:0044179 hemolysis in other organism Updated TERM hemolysis in other organism
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Updated TERM androstan-3-alpha,17-beta-diol dehydrogenase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Updated TERM 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity
2011-02-15 GO:0044402 competition with other organism Updated TERM competition with other organism
2011-02-15 GO:0051801 cytolysis in other organism involved in symbiotic interaction Updated TERM cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051802 regulation of cytolysis in other organism involved in symbiotic interaction Updated TERM regulation of cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051803 negative regulation of cytolysis in other organism involved in symbiotic interaction Updated TERM negative regulation of cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051804 positive regulation of cytolysis in other organism involved in symbiotic interaction Updated TERM positive regulation of cytolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0051671 induction of autolysin activity in other organism Updated TERM induction of autolysin activity in other organism
2011-02-15 GO:0051673 membrane disruption in other organism Updated TERM membrane disruption in other organism
2011-02-15 GO:0051709 regulation of killing of cells of other organism Updated TERM regulation of killing of cells of other organism
2011-02-15 GO:0051710 regulation of cytolysis in other organism Updated TERM regulation of cytolysis in other organism
2011-02-15 GO:0051711 negative regulation of killing of cells of other organism Updated TERM negative regulation of killing of cells of other organism
2011-02-15 GO:0051712 positive regulation of killing of cells of other organism Updated TERM positive regulation of killing of cells of other organism
2011-02-15 GO:0051713 negative regulation of cytolysis in other organism Updated TERM negative regulation of cytolysis in other organism
2011-02-15 GO:0051714 positive regulation of cytolysis in other organism Updated TERM positive regulation of cytolysis in other organism
2011-02-15 GO:0051715 cytolysis in other organism Updated TERM cytolysis in other organism
2011-02-15 GO:0051287 NAD binding Updated TERM NAD+ or NADH binding
2011-02-15 GO:0050661 NADP binding Updated TERM NADP+ or NADPH binding
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Updated TERM 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
2011-02-15 GO:0047007 pregnan-21-ol dehydrogenase (NAD+) activity Updated TERM pregnan-21-ol dehydrogenase (NAD+) activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Updated TERM pregnan-21-ol dehydrogenase (NADP+) activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Updated TERM cholate 12-alpha dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Updated TERM androsterone dehydrogenase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Updated TERM 5alpha-androstane-3beta,17beta-diol dehydrogenase activity
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Updated TERM androsterone dehydrogenase (A-specific) activity
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Updated TERM testosterone dehydrogenase (NAD+) activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Updated TERM androsterone dehydrogenase (B-specific) activity
2011-02-15 GO:0052331 hemolysis in other organism involved in symbiotic interaction Updated TERM hemolysis in other organism involved in symbiotic interaction
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Updated TERM positive regulation of prostaglandin-endoperoxide synthase activity
2011-02-15 GO:0071407 cellular response to organic cyclic compound Updated TERM cellular response to organic cyclic compound
2011-02-15 GO:0070401 NADP+ binding Updated TERM NADP+ binding
2011-02-15 GO:0070403 NAD+ binding Updated TERM NAD+ binding
2011-02-15 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding Added TERM RNA polymerase I regulatory region sequence-specific DNA binding
2011-02-15 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding Added TERM RNA polymerase I core promoter sequence-specific DNA binding
2011-02-15 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding Added TERM RNA polymerase I upstream control element sequence-specific DNA binding
2011-02-15 GO:0001166 RNA polymerase I enhancer sequence-specific DNA binding Added TERM RNA polymerase I enhancer sequence-specific DNA binding
2011-02-15 GO:0001167 RNA polymerase I transcription factor activity, sequence-specific DNA binding Added TERM sequence-specific DNA binding RNA polymerase I transcription factor activity
2011-02-15 GO:0001168 transcription factor activity, RNA polymerase I upstream control element sequence-specific binding Added TERM RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity
2011-02-15 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding Added TERM RNA polymerase I core promoter sequence-specific DNA binding transcription factor activity
2011-02-15 GO:0001170 transcription factor activity, RNA polymerase I enhancer sequence-specific binding Added TERM RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Updated TERM sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Updated TERM cholate 7-alpha-dehydrogenase activity
2011-02-15 GO:0015892 siderophore-iron transport Deleted TERM siderophore-iron transport
2011-02-15 GO:0015343 siderophore transmembrane transporter activity Updated TERM siderophore transmembrane transporter activity
2011-02-15 GO:0015344 siderophore uptake transmembrane transporter activity Updated TERM siderophore uptake transmembrane transporter activity
2011-02-15 GO:0014070 response to organic cyclic compound Updated TERM response to organic cyclic compound
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Updated TERM testosterone dehydrogenase activity
2011-02-15 GO:0031640 killing of cells of other organism Updated TERM killing of cells of other organism
2011-02-15 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway Added TERM MyD88-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035661 MyD88-dependent toll-like receptor 2 signaling pathway Added TERM MyD88-dependent toll-like receptor 2 signaling pathway
2011-02-15 GO:0035662 Toll-like receptor 4 binding Added TERM Toll-like receptor 4 binding
2011-02-15 GO:0035663 Toll-like receptor 2 binding Added TERM Toll-like receptor 2 binding
2011-02-15 GO:0035664 TIRAP-dependent toll-like receptor signaling pathway Added TERM TIRAP-dependent toll-like receptor signaling pathway
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added TERM TIRAP-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added TERM TRIF-dependent toll-like receptor signaling pathway
2011-02-15 GO:0035667 TRIF-dependent toll-like receptor 4 signaling pathway Added TERM TRIF-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added TERM TRAM-dependent toll-like receptor signaling pathway
2011-02-15 GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway Added TERM TRAM-dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:0035670 plant-type ovary development Added TERM ovule-producing ovary development
2011-02-15 GO:0035671 enone reductase activity Added TERM enone reductase activity
2011-02-15 GO:0035672 oligopeptide transmembrane transport Added TERM oligopeptide transmembrane transport
2011-02-15 GO:0035673 oligopeptide transmembrane transporter activity Added TERM oligopeptide transmembrane transporter activity
2011-02-15 GO:2000375 negative regulation of oxygen metabolic process Added TERM negative regulation of oxygen metabolic process
2011-02-15 GO:2000376 positive regulation of oxygen metabolic process Added TERM positive regulation of oxygen metabolic process
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added TERM regulation of reactive oxygen species metabolic process
2011-02-15 GO:2000378 negative regulation of reactive oxygen species metabolic process Added TERM negative regulation of reactive oxygen species metabolic process
2011-02-15 GO:2000379 positive regulation of reactive oxygen species metabolic process Added TERM positive regulation of reactive oxygen species metabolic process
2011-02-15 GO:2000332 regulation of blood microparticle formation Added TERM regulation of blood microparticle formation
2011-02-15 GO:2000333 negative regulation of blood microparticle formation Added TERM negative regulation of blood microparticle formation
2011-02-15 GO:2000334 positive regulation of blood microparticle formation Added TERM positive regulation of blood microparticle formation
2011-02-15 GO:2000335 regulation of endothelial microparticle formation Added TERM regulation of endothelial microparticle formation
2011-02-15 GO:2000336 negative regulation of endothelial microparticle formation Added TERM negative regulation of endothelial microparticle formation
2011-02-15 GO:2000337 positive regulation of endothelial microparticle formation Added TERM positive regulation of endothelial microparticle formation
2011-02-15 GO:2000338 regulation of chemokine (C-X-C motif) ligand 1 production Added TERM regulation of chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:2000339 negative regulation of chemokine (C-X-C motif) ligand 1 production Added TERM negative regulation of chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production Added TERM positive regulation of chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:0061385 fibroblast proliferation involved in heart morphogenesis Added TERM fibroblast proliferation involved in heart morphogenesis
2011-02-15 GO:0072580 bacterial-type EF-P lysine modification Added TERM bacterial-type EF-P lysine modification
2011-02-15 GO:0072581 protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine Added TERM protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine
2011-02-15 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity Added TERM 17-beta-hydroxysteroid dehydrogenase (NADP+) activity
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added TERM clathrin-mediated endocytosis
2011-02-15 GO:0072584 caveolin-mediated endocytosis Added TERM caveolin-mediated endocytosis
2011-02-15 GO:0072585 xanthosine nucleotidase activity Added TERM xanthosine nucleotidase activity
2011-02-15 GO:0072566 chemokine (C-X-C motif) ligand 1 production Added TERM chemokine (C-X-C motif) ligand 1 production
2011-02-15 GO:0072567 chemokine (C-X-C motif) ligand 2 production Added TERM chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:0072568 protein kinase C delta binding Added TERM protein kinase C delta binding
2011-02-15 GO:0072569 protein kinase C eta binding Added TERM protein kinase C eta binding
2011-02-15 GO:0072570 ADP-D-ribose binding Added TERM ADP-D-ribose binding
2011-02-15 GO:0072571 mono-ADP-D-ribose binding Added TERM mono-ADP-D-ribose binding
2011-02-15 GO:0072572 poly-ADP-D-ribose binding Added TERM poly-ADP-D-ribose binding
2011-02-15 GO:0072573 tolerance induction to lipopolysaccharide Added TERM tolerance induction to lipopolysaccharide
2011-02-15 GO:0072574 hepatocyte proliferation Added TERM hepatocyte proliferation
2011-02-15 GO:0072575 epithelial cell proliferation involved in liver morphogenesis Added TERM epithelial cell proliferation involved in liver morphogenesis
2011-02-15 GO:0072576 liver morphogenesis Added TERM liver morphogenesis
2011-02-15 GO:0072577 endothelial cell apoptotic process Added TERM endothelial cell apoptosis
2011-02-15 GO:0072578 neurotransmitter-gated ion channel clustering Added TERM neurotransmitter-gated ion channel clustering
2011-02-15 GO:0072579 glycine receptor clustering Added TERM glycine receptor clustering
2011-02-15 GO:0072586 DNA topoisomerase (ATP-hydrolyzing) regulator activity Added TERM DNA topoisomerase (ATP-hydrolyzing) regulator activity
2011-02-15 GO:0072587 DNA topoisomerase (ATP-hydrolyzing) activator activity Added TERM DNA topoisomerase (ATP-hydrolyzing) activator activity
2011-02-15 GO:0072588 box H/ACA RNP complex Added TERM box H/ACA RNP complex
2011-02-15 GO:0072589 box H/ACA scaRNP complex Added TERM box H/ACA scaRNP complex
2011-02-15 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity Added TERM N-acetyl-L-aspartate-L-glutamate ligase activity
2011-02-15 GO:0072591 citrate-L-glutamate ligase activity Added TERM citrate-L-glutamate ligase activity
2011-02-15 GO:0072592 oxygen metabolic process Added TERM oxygen metabolic process
2011-02-15 GO:0072593 reactive oxygen species metabolic process Added TERM reactive oxygen species metabolic process
2011-02-15 GO:0072594 establishment of protein localization to organelle Added TERM establishment of protein localization to organelle
2011-02-15 GO:0072595 maintenance of protein localization in organelle Added TERM maintenance of protein localization to organelle
2011-02-15 GO:0072596 establishment of protein localization to chloroplast Added TERM establishment of protein localization to chloroplast
2011-02-15 GO:0072597 maintenance of protein location in chloroplast Added TERM maintenance of protein location in chloroplast
2011-02-15 GO:0072598 protein localization to chloroplast Added TERM protein localization to chloroplast
2011-02-15 GO:0072599 establishment of protein localization to endoplasmic reticulum Added TERM establishment of protein localization in endoplasmic reticulum
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added TERM establishment of protein localization in Golgi
2011-02-15 GO:0072655 establishment of protein localization to mitochondrion Added TERM establishment of protein localization in mitochondrion
2011-02-15 GO:0072656 maintenance of protein location in mitochondrion Added TERM maintenance of protein location in mitochondrion
2011-02-15 GO:0072657 protein localization to membrane Added TERM protein localization in membrane
2011-02-15 GO:0072658 maintenance of protein location in membrane Added TERM maintenance of protein location in membrane
2011-02-15 GO:0072659 protein localization to plasma membrane Added TERM protein localization in plasma membrane
2011-02-15 GO:0072660 maintenance of protein location in plasma membrane Added TERM maintenance of protein location in plasma membrane
2011-02-15 GO:0072661 protein targeting to plasma membrane Added TERM protein targeting to plasma membrane
2011-02-15 GO:0072662 protein localization to peroxisome Added TERM protein localization to peroxisome
2011-02-15 GO:0072663 establishment of protein localization to peroxisome Added TERM establishment of protein localization to peroxisome
2011-02-15 GO:0072664 maintenance of protein location in peroxisome Added TERM maintenance of protein location in peroxisome
2011-02-15 GO:0072665 protein localization to vacuole Added TERM protein localization to vacuole
2011-02-15 GO:0072666 establishment of protein localization to vacuole Added TERM establishment of protein localization to vacuole
2011-02-15 GO:0072667 maintenance of protein location in vacuole Added TERM maintenance of protein location in vacuole
2011-02-15 GO:0072668 obsolete tubulin complex biogenesis Added TERM tubulin complex biogenesis
2011-02-15 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production Added TERM regulation of chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production Added TERM negative regulation of chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production Added TERM positive regulation of chemokine (C-X-C motif) ligand 2 production
2011-02-15 GO:2000344 positive regulation of acrosome reaction Added TERM positive regulation of acrosome reaction
2011-02-15 GO:2000345 regulation of hepatocyte proliferation Added TERM regulation of hepatocyte proliferation
2011-02-15 GO:2000346 negative regulation of hepatocyte proliferation Added TERM negative regulation of hepatocyte proliferation
2011-02-15 GO:2000347 positive regulation of hepatocyte proliferation Added TERM positive regulation of hepatocyte proliferation
2011-02-15 GO:2000348 regulation of CD40 signaling pathway Added TERM regulation of CD40 signaling pathway
2011-02-15 GO:2000349 negative regulation of CD40 signaling pathway Added TERM negative regulation of CD40 signaling pathway
2011-02-15 GO:2000350 positive regulation of CD40 signaling pathway Added TERM positive regulation of CD40 signaling pathway
2011-02-15 GO:2000351 regulation of endothelial cell apoptotic process Added TERM regulation of endothelial cell apoptosis
2011-02-15 GO:2000352 negative regulation of endothelial cell apoptotic process Added TERM negative regulation of endothelial cell apoptosis
2011-02-15 GO:2000353 positive regulation of endothelial cell apoptotic process Added TERM positive regulation of endothelial cell apoptosis
2011-02-15 GO:2000354 regulation of ovarian follicle development Added TERM regulation of ovarian follicle development
2011-02-15 GO:2000355 negative regulation of ovarian follicle development Added TERM negative regulation of ovarian follicle development
2011-02-15 GO:2000356 regulation of kidney smooth muscle cell differentiation Added TERM regulation of kidney smooth muscle cell differentiation
2011-02-15 GO:2000357 negative regulation of kidney smooth muscle cell differentiation Added TERM negative regulation of kidney smooth muscle cell differentiation
2011-02-15 GO:2000358 positive regulation of kidney smooth muscle cell differentiation Added TERM positive regulation of kidney smooth muscle cell differentiation
2011-02-15 GO:2000359 regulation of binding of sperm to zona pellucida Added TERM regulation of binding of sperm to zona pellucida
2011-02-15 GO:2000360 negative regulation of binding of sperm to zona pellucida Added TERM negative regulation of binding of sperm to zona pellucida
2011-02-15 GO:2000361 regulation of prostaglandin-E synthase activity Added TERM regulation of prostaglandin-E synthase activity
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added TERM negative regulation of prostaglandin-E synthase activity
2011-02-15 GO:2000363 positive regulation of prostaglandin-E synthase activity Added TERM positive regulation of prostaglandin-E synthase activity
2011-02-15 GO:2000364 regulation of STAT protein import into nucleus Added TERM regulation of STAT protein import into nucleus
2011-02-15 GO:2000365 negative regulation of STAT protein import into nucleus Added TERM negative regulation of STAT protein import into nucleus
2011-02-15 GO:2000366 positive regulation of STAT protein import into nucleus Added TERM positive regulation of STAT protein import into nucleus
2011-02-15 GO:2000367 regulation of acrosomal vesicle exocytosis Added TERM regulation of acrosomal vesicle exocytosis
2011-02-15 GO:2000368 positive regulation of acrosomal vesicle exocytosis Added TERM positive regulation of acrosomal vesicle exocytosis
2011-02-15 GO:2000369 regulation of clathrin-mediated endocytosis Added TERM regulation of clathrin-mediated endocytosis
2011-02-15 GO:2000370 positive regulation of clathrin-mediated endocytosis Added TERM positive regulation of clathrin-mediated endocytosis
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added TERM regulation of DNA topoisomerase (ATP-hydrolyzing) activity
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added TERM negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added TERM positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
2011-02-15 GO:2000374 regulation of oxygen metabolic process Added TERM regulation of oxygen metabolic process

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2011-02-15 GO:0043222 SMC/kleisin ring complex Deleted DEFINITION A molecular ring complex composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1 and Smc3, and the kleisin protein Scc1.
2011-02-15 GO:0072557 IPAF inflammasome complex Deleted DEFINITION A protein complex that consists of four components, NALP1, PYCARD (ASC)(27), caspase-1 and caspase-5 and includes among its functions that of being the primary mediator of susceptibility to anthrax lethal toxin.
2011-02-15 GO:0042128 nitrate assimilation Deleted DEFINITION The uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.
2011-02-15 GO:0071915 protein-lysine lysylation Deleted DEFINITION The addition of lysine to a lysine residue in a protein, producing N6-(lysyl)lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
2011-02-15 GO:0072558 NLRP1 inflammasome complex Deleted DEFINITION A protein complex that consists of three components, NALP3, PYCARD and caspase-1 and includes among its functions the sensing of various stimuli including anti-viral compounds R837 and R848, bacterial mRNA, gout-associated crystals, bacterial toxins derived from Listeria M., staphylococcus A. and shigella F.
2011-02-15 GO:0031429 box H/ACA snoRNP complex Deleted DEFINITION A ribonucleoprotein complex containing small nucleolar RNA of the box H/ACA type.
2011-02-15 GO:0005183 gonadotropin hormone-releasing hormone activity Deleted DEFINITION The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, GnRH causes the release of follicle-stimulating hormone and luteinizing hormone by the anterior pituitary.
2011-02-15 GO:0071407 cellular response to organic cyclic compound Deleted DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic substance stimulus.
2011-02-15 GO:0016362 activin receptor activity, type II Deleted DEFINITION Combining with activin to initiate a change in cell activity; upon ligand binding, binds to catalyzes the phosphorylation of type I activin receptor.
2011-02-15 GO:0002755 MyD88-dependent toll-like receptor signaling pathway Deleted DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor and relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0014070 response to organic cyclic compound Deleted DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic substance stimulus.
2011-02-15 GO:0008278 cohesin complex Deleted DEFINITION A protein complex required for sister chromatid cohesion in eukaryotes.
2011-02-15 GO:0050661 NADP binding Deleted DEFINITION Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP, or the reduced form, NADPH.
2011-02-15 GO:0005025 transforming growth factor beta receptor activity, type I Deleted DEFINITION Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity.
2011-02-15 GO:0072559 NLRP3 inflammasome complex Deleted DEFINITION A protein complex that consists of three components, IPAF, NAIP and caspase-1 and includes among its functions the sensing of flagellin derived from Legionella P., Salmonella T., pseudomonas A. and shigella F.
2011-02-15 GO:0048903 anterior lateral line neuromast hair cell differentiation Deleted DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2011-02-15 GO:0070401 NADP+ binding Deleted DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity Deleted DEFINITION Any process that modulates the rate, frequency or extent of prostaglandin-endoperoxidase activity. Prostaglandin-endoperoxidase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity Deleted DEFINITION Catalysis of the reaction: 3-beta-hydroxy-delta(5)-steroid + NAD+ = 3-oxo-delta(5)-steroid + NADH + H+.
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Deleted DEFINITION Any process that increases the rate, frequency or extent of prostaglandin-endoperoxidase activity. Prostaglandin-endoperoxidase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0031428 box C/D snoRNP complex Deleted DEFINITION A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type.
2011-02-15 GO:0051287 NAD binding Deleted DEFINITION Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD, or the reduced form, NADH.
2011-02-15 GO:0044402 competition with other organism Deleted DEFINITION Any process in which an organism within a multispecies research community gains an advantage in growth or survival over another organism of a different species in that research community.
2011-02-15 GO:0009341 beta-galactosidase complex Deleted DEFINITION A multimeric enzyme complex that in E. coli is a heterooctamer made up of four alpha subunits and four beta subunits. Catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.
2011-02-15 GO:0005732 small nucleolar ribonucleoprotein complex Deleted DEFINITION A ribonucleoprotein complex that contains a small nucleolar RNA (snoRNA) and associated proteins, and is found in eukaryotic cells. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2011-02-15 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding Deleted DEFINITION Interacting selectively and non-covalently with a RNA polymerase II (Pol II) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2011-02-15 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the core element.
2011-02-15 GO:0001167 RNA polymerase I transcription factor activity, sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
2011-02-15 GO:0001168 transcription factor activity, RNA polymerase I upstream control element sequence-specific binding Added DEFINITION Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I.
2011-02-15 GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity Deleted DEFINITION Catalysis of the reaction: NADP+ + 7-beta-hydroxysteroid = NADPH + H+ + 7-oxosteroid.
2011-02-15 GO:0043113 receptor clustering Deleted DEFINITION Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
2011-02-15 GO:0014070 response to organic cyclic compound Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2011-02-15 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0035662 Toll-like receptor 4 binding Added DEFINITION Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0072558 NLRP1 inflammasome complex Added DEFINITION A protein complex that consists of three components, NALP3, PYCARD and caspase-1, and includes among its functions the sensing of various stimuli including anti-viral compounds R837 and R848, bacterial mRNA, gout-associated crystals, bacterial toxins derived from Listeria monocytogenes, Staphylococcus aureus and Shigella flexneri.
2011-02-15 GO:0072569 protein kinase C eta binding Added DEFINITION Interacting selectively and non-covalently with protein kinase C eta.
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added DEFINITION An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
2011-02-15 GO:0072585 xanthosine nucleotidase activity Added DEFINITION Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
2011-02-15 GO:0072594 establishment of protein localization to organelle Added DEFINITION The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
2011-02-15 GO:0072595 maintenance of protein localization in organelle Added DEFINITION Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
2011-02-15 GO:0072659 protein localization to plasma membrane Added DEFINITION A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
2011-02-15 GO:0072664 maintenance of protein location in peroxisome Added DEFINITION Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.
2011-02-15 GO:2000336 negative regulation of endothelial microparticle formation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation.
2011-02-15 GO:2000347 positive regulation of hepatocyte proliferation Added DEFINITION Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
2011-02-15 GO:2000356 regulation of kidney smooth muscle cell differentiation Added DEFINITION Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation.
2011-02-15 GO:2000370 positive regulation of clathrin-mediated endocytosis Added DEFINITION Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
2011-02-15 GO:2000376 positive regulation of oxygen metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.
2011-02-15 GO:0008278 cohesin complex Added DEFINITION A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
2011-02-15 GO:0016362 activin receptor activity, type II Added DEFINITION Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0035678 neuromast hair cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
2011-02-15 GO:0042128 nitrate assimilation Added DEFINITION The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.
2011-02-15 GO:0070401 NADP+ binding Added DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 GO:0072559 NLRP3 inflammasome complex Added DEFINITION A protein complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.
2011-02-15 GO:0072567 chemokine (C-X-C motif) ligand 2 production Added DEFINITION The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2011-02-15 GO:0072574 hepatocyte proliferation Added DEFINITION The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.
2011-02-15 GO:0072580 bacterial-type EF-P lysine modification Added DEFINITION The modification of a lysine residue in a protein, producing (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).
2011-02-15 GO:0072587 DNA topoisomerase (ATP-hydrolyzing) activator activity Added DEFINITION Increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
2011-02-15 GO:0072668 obsolete tubulin complex biogenesis Added DEFINITION A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled.
2011-02-15 GO:2000332 regulation of blood microparticle formation Added DEFINITION Any process that modulates the frequency, rate or extent of blood microparticle formation.
2011-02-15 GO:2000333 negative regulation of blood microparticle formation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.
2011-02-15 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2011-02-15 GO:2000345 regulation of hepatocyte proliferation Added DEFINITION Any process that modulates the frequency, rate or extent of hepatocyte proliferation.
2011-02-15 GO:2000346 negative regulation of hepatocyte proliferation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.
2011-02-15 GO:2000352 negative regulation of endothelial cell apoptotic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptosis.
2011-02-15 GO:2000353 positive regulation of endothelial cell apoptotic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of endothelial cell apoptosis.
2011-02-15 GO:2000354 regulation of ovarian follicle development Added DEFINITION Any process that modulates the frequency, rate or extent of ovarian follicle development.
2011-02-15 GO:2000375 negative regulation of oxygen metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.
2011-02-15 GO:0035677 posterior lateral line neuromast hair cell development Added DEFINITION The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
2011-02-15 GO:0035679 anterior lateral line neuromast hair cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
2011-02-15 GO:0035680 posterior lateral line neuromast hair cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
2011-02-15 GO:0043113 receptor clustering Added DEFINITION The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
2011-02-15 GO:0061385 fibroblast proliferation involved in heart morphogenesis Added DEFINITION The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.
2011-02-15 GO:0071915 protein-lysine lysylation Added DEFINITION The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
2011-02-15 GO:0072542 protein phosphatase activator activity Added DEFINITION Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
2011-02-15 GO:0072572 poly-ADP-D-ribose binding Added DEFINITION Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.
2011-02-15 GO:0072573 tolerance induction to lipopolysaccharide Added DEFINITION Tolerance induction directed at lipopolysaccharide antigens.
2011-02-15 GO:0072575 epithelial cell proliferation involved in liver morphogenesis Added DEFINITION The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.
2011-02-15 GO:0072577 endothelial cell apoptotic process Added DEFINITION The process of apoptosis in endothelial cells. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
2011-02-15 GO:0072579 glycine receptor clustering Added DEFINITION The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.
2011-02-15 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity Added DEFINITION Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added DEFINITION The directed movement of a protein to a specific location in the Golgi apparatus.
2011-02-15 GO:0072660 maintenance of protein location in plasma membrane Added DEFINITION Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.
2011-02-15 GO:0072662 protein localization to peroxisome Added DEFINITION A process in which a protein is transported to, or maintained at, a location in a peroxisome.
2011-02-15 GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production Added DEFINITION Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2011-02-15 GO:2000344 positive regulation of acrosome reaction Added DEFINITION Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
2011-02-15 GO:2000348 regulation of CD40 signaling pathway Added DEFINITION Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.
2011-02-15 GO:0015892 siderophore-iron transport Deleted DEFINITION The directed movement of iron-siderophores into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Iron-siderophores are low molecular weight Fe(III)-chelating substances in the iron-bound form.
2011-02-15 GO:2000366 positive regulation of STAT protein import into nucleus Added DEFINITION Any process that activates or increases the frequency, rate or extent of STAT protein import into nucleus.
2011-02-15 GO:2000358 positive regulation of kidney smooth muscle cell differentiation Added DEFINITION Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation.
2011-02-15 GO:2000363 positive regulation of prostaglandin-E synthase activity Added DEFINITION Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.
2011-02-15 GO:2000351 regulation of endothelial cell apoptotic process Added DEFINITION Any process that modulates the frequency, rate or extent of endothelial cell apoptosis.
2011-02-15 GO:2000359 regulation of binding of sperm to zona pellucida Added DEFINITION Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida.
2011-02-15 GO:2000360 negative regulation of binding of sperm to zona pellucida Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.
2011-02-15 GO:2000361 regulation of prostaglandin-E synthase activity Added DEFINITION Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity.
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added DEFINITION Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2011-02-15 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding Added DEFINITION Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I.
2011-02-15 GO:0001170 transcription factor activity, RNA polymerase I enhancer sequence-specific binding Added DEFINITION Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I.
2011-02-15 GO:0005025 transforming growth factor beta receptor activity, type I Added DEFINITION Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.
2011-02-15 GO:0005732 small nucleolar ribonucleoprotein complex Added DEFINITION A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2011-02-15 GO:0035671 enone reductase activity Added DEFINITION Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.
2011-02-15 GO:0035672 oligopeptide transmembrane transport Added DEFINITION The directed movement of an oligopeptide across a membrane by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
2011-02-15 GO:0035673 oligopeptide transmembrane transporter activity Added DEFINITION Catalysis of the transfer of oligopeptides from one side of the membrane to the other.
2011-02-15 GO:0044402 competition with other organism Added DEFINITION Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community.
2011-02-15 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity Added DEFINITION Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0072491 toluene-containing compound catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.
2011-02-15 GO:0072557 IPAF inflammasome complex Added DEFINITION A protein complex that consists of four components, NALP1, PYCARD (ASC)(27), caspase-1 and caspase-5, and includes among its functions that of being the primary mediator of susceptibility to anthrax lethal toxin.
2011-02-15 GO:0072566 chemokine (C-X-C motif) ligand 1 production Added DEFINITION The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2011-02-15 GO:0072568 protein kinase C delta binding Added DEFINITION Interacting selectively and non-covalently with protein kinase C delta.
2011-02-15 GO:0072576 liver morphogenesis Added DEFINITION The process in which the anatomical structures of the liver are generated and organized.
2011-02-15 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.
2011-02-15 GO:0072586 DNA topoisomerase (ATP-hydrolyzing) regulator activity Added DEFINITION Modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
2011-02-15 GO:0072588 box H/ACA RNP complex Added DEFINITION A ribonucleoprotein complex that contains an RNA of the box H/ACA type, a subtype of the small nucleolar RNA (snoRNA) family. RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs, although some have evolved other functions. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and on U2 small nuclear RNA (U2 snRNA).
2011-02-15 GO:0072597 maintenance of protein location in chloroplast Added DEFINITION Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere.
2011-02-15 GO:0072655 establishment of protein localization to mitochondrion Added DEFINITION The directed movement of a protein to a specific location in the mitochondrion.
2011-02-15 GO:0072665 protein localization to vacuole Added DEFINITION A process in which a protein is transported to, or maintained at, a location in a vacuole.
2011-02-15 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production Added DEFINITION Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2011-02-15 GO:2000349 negative regulation of CD40 signaling pathway Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity.
2011-02-15 GO:2000367 regulation of acrosomal vesicle exocytosis Added DEFINITION Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis.
2011-02-15 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a RNA polymerase II (Pol II) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2011-02-15 GO:0005183 gonadotropin hormone-releasing hormone activity Added DEFINITION The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary.
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0048903 anterior lateral line neuromast hair cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2011-02-15 GO:0050661 NADP binding Added DEFINITION Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
2011-02-15 GO:0051287 NAD binding Added DEFINITION Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
2011-02-15 GO:0072570 ADP-D-ribose binding Added DEFINITION Interacting selectively and non-covalently with ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
2011-02-15 GO:0072578 neurotransmitter-gated ion channel clustering Added DEFINITION The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.
2011-02-15 GO:0072584 caveolin-mediated endocytosis Added DEFINITION An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.
2011-02-15 GO:0072592 oxygen metabolic process Added DEFINITION The chemical reactions and pathways involving diatomic oxygen (O2).
2011-02-15 GO:0072598 protein localization to chloroplast Added DEFINITION A process in which a protein is transported to, or maintained at, a location in a chloroplast.
2011-02-15 GO:0072661 protein targeting to plasma membrane Added DEFINITION The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
2011-02-15 GO:0072663 establishment of protein localization to peroxisome Added DEFINITION The directed movement of a protein to a specific location in a peroxisome.
2011-02-15 GO:2000339 negative regulation of chemokine (C-X-C motif) ligand 1 production Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2011-02-15 GO:2000369 regulation of clathrin-mediated endocytosis Added DEFINITION Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added DEFINITION Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2011-02-15 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.
2011-02-15 GO:0001166 RNA polymerase I enhancer sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2011-02-15 GO:0035663 Toll-like receptor 2 binding Added DEFINITION Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.
2011-02-15 GO:0035664 TIRAP-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0035670 plant-type ovary development Added DEFINITION The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.
2011-02-15 GO:0035674 tricarboxylic acid transmembrane transport Added DEFINITION The process in which tricarboxylic acids are transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2011-02-15 GO:0035676 anterior lateral line neuromast hair cell development Added DEFINITION The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
2011-02-15 GO:0072571 mono-ADP-D-ribose binding Added DEFINITION Interacting selectively and non-covalently with monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
2011-02-15 GO:0072589 box H/ACA scaRNP complex Added DEFINITION A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.
2011-02-15 GO:0072591 citrate-L-glutamate ligase activity Added DEFINITION Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.
2011-02-15 GO:0072657 protein localization to membrane Added DEFINITION A process in which a protein is transported to, or maintained in, a specific location in a membrane.
2011-02-15 GO:0072666 establishment of protein localization to vacuole Added DEFINITION The directed movement of a protein to a specific location in a vacuole.
2011-02-15 GO:2000357 negative regulation of kidney smooth muscle cell differentiation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation.
2011-02-15 GO:2000364 regulation of STAT protein import into nucleus Added DEFINITION Any process that modulates the frequency, rate or extent of STAT protein import into nucleus.
2011-02-15 GO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production Added SYNONYM positive regulation of SCYB1 production
2011-02-15 GO:2000361 regulation of prostaglandin-E synthase activity Added SYNONYM regulation of PGE2 isomerase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Added SYNONYM glycerone transferase activity
2011-02-15 GO:0014070 response to organic cyclic compound Added SYNONYM response to organic cyclic substance
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM positive regulation of topoisomerase
2011-02-15 GO:0072584 caveolin-mediated endocytosis Added SYNONYM caveolae-mediated endocytosis
2011-02-15 GO:2000337 positive regulation of endothelial microparticle formation Added SYNONYM positive regulation of endothelial microparticle generation
2011-02-15 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM regulation of PG synthetase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Added SYNONYM 3beta,20alpha-hydroxysteroid oxidoreductase activity
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM regulation of type II DNA topoisomerase activity
2011-02-15 GO:0060043 regulation of cardiac muscle cell proliferation Added SYNONYM regulation of cardiomyocyte proliferation
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added SYNONYM regulation of ROS metabolic process
2011-02-15 GO:0072572 poly-ADP-D-ribose binding Added SYNONYM pADPr binding
2011-02-15 GO:0072571 mono-ADP-D-ribose binding Added SYNONYM mADPr binding
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Added SYNONYM 12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
2011-02-15 GO:0035662 Toll-like receptor 4 binding Added SYNONYM TLR4 binding
2011-02-15 GO:0072589 box H/ACA scaRNP complex Added SYNONYM nucleoplasmic box H/ACA RNP pseudouridylase complex
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added SYNONYM negative regulation of PGE2 isomerase activity
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added SYNONYM TRAM-dependent toll-like receptor signalling pathway
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM positive regulation of PG synthetase activity
2011-02-15 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding Added SYNONYM RNA polymerase I core element sequence-specific DNA binding
2011-02-15 GO:0051713 negative regulation of cytolysis in other organism Added SYNONYM negative regulation of cytolysis of cells of another organism
2011-02-15 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production Added SYNONYM negative regulation of MIP2 production
2011-02-15 GO:2000375 negative regulation of oxygen metabolic process Added SYNONYM negative regulation of oxygen metabolism
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Added SYNONYM 3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0015892 siderophore-iron transport Deleted SYNONYM iron-siderochrome transport
2011-02-15 GO:0015892 siderophore-iron transport Deleted SYNONYM iron-siderophore transport
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Deleted SYNONYM 7alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Deleted SYNONYM 3(or 17)alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Deleted SYNONYM 3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3beta(or 20alpha)-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3beta,20alpha-hydroxysteroid oxidoreductase activity
2011-02-15 GO:0009341 beta-galactosidase complex Added DEFINITION A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.
2011-02-15 GO:0031428 box C/D snoRNP complex Added DEFINITION A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs.
2011-02-15 GO:0031429 box H/ACA snoRNP complex Added DEFINITION A box H/ACA RNP complex that is located in the nucleolus.
2011-02-15 GO:0035661 MyD88-dependent toll-like receptor 2 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.
2011-02-15 GO:0072581 protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine Added DEFINITION The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
2011-02-15 GO:0072593 reactive oxygen species metabolic process Added DEFINITION The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
2011-02-15 GO:0072656 maintenance of protein location in mitochondrion Added DEFINITION Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.
2011-02-15 GO:2000335 regulation of endothelial microparticle formation Added DEFINITION Any process that modulates the frequency, rate or extent of endothelial microparticle formation.
2011-02-15 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production Added DEFINITION Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2011-02-15 GO:2000355 negative regulation of ovarian follicle development Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
2011-02-15 GO:2000368 positive regulation of acrosomal vesicle exocytosis Added DEFINITION Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
2011-02-15 GO:2000374 regulation of oxygen metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of oxygen metabolic process.
2011-02-15 GO:2000378 negative regulation of reactive oxygen species metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.
2011-02-15 GO:2000379 positive regulation of reactive oxygen species metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
2011-02-15 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding Added DEFINITION Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I.
2011-02-15 GO:0002755 MyD88-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2011-02-15 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity Added DEFINITION Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H+.
2011-02-15 GO:0035667 TRIF-dependent toll-like receptor 4 signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
2011-02-15 GO:0035675 neuromast hair cell development Added DEFINITION The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
2011-02-15 GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added DEFINITION Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2011-02-15 GO:0071407 cellular response to organic cyclic compound Added DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2011-02-15 GO:0072596 establishment of protein localization to chloroplast Added DEFINITION The directed movement of a protein to a specific location in a chloroplast.
2011-02-15 GO:0072599 establishment of protein localization to endoplasmic reticulum Added DEFINITION The directed movement of a protein to a specific location in the endoplasmic reticulum.
2011-02-15 GO:0072658 maintenance of protein location in membrane Added DEFINITION Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.
2011-02-15 GO:0072667 maintenance of protein location in vacuole Added DEFINITION Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.
2011-02-15 GO:2000334 positive regulation of blood microparticle formation Added DEFINITION Any process that activates or increases the frequency, rate or extent of blood microparticle formation.
2011-02-15 GO:2000337 positive regulation of endothelial microparticle formation Added DEFINITION Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation.
2011-02-15 GO:2000338 regulation of chemokine (C-X-C motif) ligand 1 production Added DEFINITION Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2011-02-15 GO:2000350 positive regulation of CD40 signaling pathway Added DEFINITION Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.
2011-02-15 GO:2000365 negative regulation of STAT protein import into nucleus Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of STAT protein import into nucleus.
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Added SYNONYM dehydrogenase, 3beta,20alpha-hydroxy steroid
2011-02-15 GO:0051710 regulation of cytolysis in other organism Added SYNONYM regulation of cytolysis of cells of another organism
2011-02-15 GO:0035669 TRAM-dependent toll-like receptor 4 signaling pathway Added SYNONYM TRAM-dependent toll-like receptor 4 signalling pathway
2011-02-15 GO:2000334 positive regulation of blood microparticle formation Added SYNONYM positive regulation of microparticle generation
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added SYNONYM negative regulation of prostaglandin endoperoxide E isomerase activity
2011-02-15 GO:2000377 regulation of reactive oxygen species metabolic process Added SYNONYM regulation of reactive oxygen species metabolism
2011-02-15 GO:2000339 negative regulation of chemokine (C-X-C motif) ligand 1 production Added SYNONYM negative regulation of SCYB1 production
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM positive regulation of fatty acid cyclooxygenase activity
2011-02-15 GO:2000351 regulation of endothelial cell apoptotic process Added SYNONYM regulation of apoptosis of endothelial cells
2011-02-15 GO:2000352 negative regulation of endothelial cell apoptotic process Added SYNONYM negative regulation of programmed cell death of endothelial cells by apoptosis
2011-02-15 GO:0015891 siderophore transport Added SYNONYM siderophore-iron transport
2011-02-15 GO:0051801 cytolysis in other organism involved in symbiotic interaction Added SYNONYM cytolysis of cells in other organism involved in symbiotic interaction
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Added SYNONYM dihydroxyacetonetransferase activity
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Added SYNONYM 7-alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added SYNONYM clathrin-dependent endocytosis
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM regulation of DNA-gyrase activity
2011-02-15 GO:0042927 siderophore transporter activity Added SYNONYM siderophore-iron transporter activity
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Added SYNONYM 17beta-hydroxy steroid dehydrogenase
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of DNA-gyrase activity
2011-02-15 GO:2000335 regulation of endothelial microparticle formation Added SYNONYM regulation of endothelial microparticle generation
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of deoxyribonucleic topoisomerase activity
2011-02-15 GO:0072569 protein kinase C eta binding Added SYNONYM PRKCH binding
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Added SYNONYM 12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added SYNONYM TRIF-dependent toll-like receptor signalling pathway
2011-02-15 GO:2000362 negative regulation of prostaglandin-E synthase activity Added SYNONYM negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added SYNONYM TIRAP-dependent toll-like receptor 4 signalling pathway
2011-02-15 GO:2000373 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM positive regulation of DNA topoisomerase IV activity
2011-02-15 GO:2000353 positive regulation of endothelial cell apoptotic process Added SYNONYM positive regulation of killing of endothelial cells
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM dehydrogenase, 3beta,20alpha-hydroxy steroid
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid dehydrogenase (A-specific)
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 17beta-hydroxy steroid dehydrogenase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 3beta-hydroxy steroid dehydrogenase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM 3beta-hydroxysteroid dehydrogenase
2011-02-15 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Deleted SYNONYM beta-hydroxy steroid dehydrogenase
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Deleted SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Deleted SYNONYM 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Deleted SYNONYM 3alpha,17beta-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid dehydrogenase (B-specific)
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid oxidoreductase activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 20beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 3alpha(or 20beta)-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM 3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM NADH-20beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM dehydrogenase, 20beta-hydroxy steroid
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM delta4-3-ketosteroid hydrogenase activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM 21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM 21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM NADP-21-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM 3-beta-HSD activity
2011-02-15 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Deleted SYNONYM progesterone reductase activity
2011-02-15 GO:0047042 androsterone dehydrogenase (B-specific) activity Deleted SYNONYM 3-alpha-HSD activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM (R)-20-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0072568 protein kinase C delta binding Added SYNONYM PRKCD binding
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Added SYNONYM NADH-20beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:2000336 negative regulation of endothelial microparticle formation Added SYNONYM negative regulation of endothelial microparticle release
2011-02-15 GO:0047026 androsterone dehydrogenase (A-specific) activity Added SYNONYM 3alpha-hydroxysteroid dehydrogenase (A-specific)
2011-02-15 GO:0072577 endothelial cell apoptotic process Added SYNONYM programmed cell death, endothelial cells
2011-02-15 GO:0035668 TRAM-dependent toll-like receptor signaling pathway Added SYNONYM TRAM-dependent TLR signaling pathway
2011-02-15 GO:0072583 clathrin-mediated endocytosis Added SYNONYM clathrin coated pit-dependent endocytosis
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added SYNONYM MyD88 adapter-like dependent toll-like receptor 4 signaling pathway
2011-02-15 GO:2000354 regulation of ovarian follicle development Added SYNONYM regulation of follicular phase
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added SYNONYM establishment of protein localisation to Golgi
2011-02-15 GO:2000379 positive regulation of reactive oxygen species metabolic process Added SYNONYM positive regulation of reactive oxygen species metabolism
2011-02-15 GO:0047035 testosterone dehydrogenase (NAD+) activity Added SYNONYM 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
2011-02-15 GO:0031429 box H/ACA snoRNP complex Added SYNONYM box H/ACA snoRNP pseudouridylase complex
2011-02-15 GO:2000349 negative regulation of CD40 signaling pathway Added SYNONYM negative regulation of CD40 signalling pathway
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Added SYNONYM 20alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0060585 positive regulation of prostaglandin-endoperoxide synthase activity Added SYNONYM positive regulation of (PG)H synthase activity
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of topoisomerase II
2011-02-15 GO:0072600 establishment of protein localization to Golgi Added SYNONYM establishment of protein localisation to Golgi apparatus
2011-02-15 GO:0031640 killing of cells of other organism Added SYNONYM killing of cells of another organism
2011-02-15 GO:0015344 siderophore uptake transmembrane transporter activity Added SYNONYM siderophore-iron uptake transmembrane transporter activity
2011-02-15 GO:0072596 establishment of protein localization to chloroplast Added SYNONYM establishment of protein localisation to chloroplast
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Added SYNONYM 12alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:2000367 regulation of acrosomal vesicle exocytosis Added SYNONYM regulation of acrosome exocytosis
2011-02-15 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production Added SYNONYM positive regulation of MIP2 production
2011-02-15 GO:2000372 negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM negative regulation of DNA topoisomerase II
2011-02-15 GO:0051712 positive regulation of killing of cells of other organism Added SYNONYM positive regulation of killing of cells of other organism
2011-02-15 GO:0035666 TRIF-dependent toll-like receptor signaling pathway Added SYNONYM TRIF-dependent TLR signaling pathway
2011-02-15 GO:0072577 endothelial cell apoptotic process Added SYNONYM killing of endothelial cells
2011-02-15 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity Added SYNONYM regulation of topoisomerase
2011-02-15 GO:0071407 cellular response to organic cyclic compound Added SYNONYM cellular response to organic cyclic substance
2011-02-15 GO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway Added SYNONYM TIRAP-dependent TLR4 signaling pathway
2011-02-15 GO:0035661 MyD88-dependent toll-like receptor 2 signaling pathway Added SYNONYM MyD88-dependent toll-like receptor 2 signalling pathway
2011-02-15 GO:0072577 endothelial cell apoptotic process Added SYNONYM apoptosis of endothelial cells
2011-02-15 GO:0051714 positive regulation of cytolysis in other organism Added SYNONYM positive regulation of cytolysis of cells of another organism
2011-02-15 GO:2000333 negative regulation of blood microparticle formation Added SYNONYM negative regulation of microparticle generation
2011-02-15 GO:2000368 positive regulation of acrosomal vesicle exocytosis Added SYNONYM positive regulation of acrosome exocytosis
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Deleted SYNONYM 7alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0008709 cholate 7-alpha-dehydrogenase activity Deleted SYNONYM 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM dihydroxyacetonetransferase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Deleted SYNONYM 12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Deleted SYNONYM 12beta-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Deleted SYNONYM 12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Deleted SYNONYM 20alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Deleted SYNONYM 20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity
2011-02-15 GO:0047007 pregnan-21-ol dehydrogenase (NAD+) activity Deleted SYNONYM 21-hydroxysteroid:NAD+ 21-oxidoreductase activity
2011-02-15 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Deleted SYNONYM 21-hydroxysteroid:NADP+ 21-oxidoreductase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM 12alpha-hydroxy steroid dehydrogenase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM 12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM 12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047013 cholate 12-alpha dehydrogenase activity Deleted SYNONYM NADP-12alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047023 androsterone dehydrogenase activity Deleted SYNONYM 3(17)alpha-hydroxysteroid dehydrogenase activity
2011-02-15 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Deleted SYNONYM cortisone reductase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM dihydroxyacetone transferase activity
2011-02-15 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Deleted SYNONYM glycerone transferase activity
2011-02-15 GO:2000360 negative regulation of binding of sperm to zona pellucida Added SYNONYM negative regulation of ZPG binding
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