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GO Term History: Displaying 500 audit records for all terms for the date 2010-12-17

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2010-12-17 GO:0072498 embryonic skeletal joint development Added RELATION is a GO:0048706 (embryonic skeletal system development)
2010-12-17 GO:0072499 photoreceptor cell axon guidance Added RELATION is a GO:0007411 (axon guidance)
2010-12-17 GO:0005759 mitochondrial matrix Added SECONDARY GO:0031980 (mitochondrial lumen)
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added RELATION part of GO:0060070 (canonical Wnt signaling pathway)
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added RELATION is a GO:0031623 (receptor internalization)
2010-12-17 GO:0060113 inner ear receptor cell differentiation Added DEFINITION The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.
2010-12-17 GO:0060219 camera-type eye photoreceptor cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
2010-12-17 GO:0060222 regulation of retinal cone cell fate commitment Added DEFINITION Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
2010-12-17 GO:0060223 retinal rod cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2010-12-17 GO:0060374 mast cell differentiation Added DEFINITION The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
2010-12-17 GO:0060503 bud dilation involved in lung branching Added DEFINITION The process in which a bud in the lung increases radially.
2010-12-17 GO:0075114 negative regulation by symbiont of host transmembrane receptor-mediated signal transduction Added DEFINITION Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075158 negative regulation of G-protein coupled receptor protein signaling pathway in response to host Added DEFINITION Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075162 regulation of G-protein beta subunit-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075163 positive regulation of G-protein beta subunit-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075169 positive regulation of symbiont protein kinase-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075173 negative regulation of MAP kinase-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075180 regulation of transcription in response to host Added DEFINITION Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075187 hyphopodium formation on or near host Added DEFINITION The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075250 negative regulation of aeciospore formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
2010-12-17 GO:0075268 regulation of aecium development Added DEFINITION Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0075269 positive regulation of aecium development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0075273 positive regulation of zygosporangium development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
2010-12-17 GO:0075288 negative regulation of sporangiospore formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
2010-12-17 GO:0075298 regulation of zygospore formation Added DEFINITION Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
2010-12-17 GO:0085044 disassembly by symbiont of host cuticle Added DEFINITION The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090112 COPII vesicle uncoating Added DEFINITION The process in which COPII vesicle coat proteins are disassembled, and released.
2010-12-17 GO:0072495 host cell Cajal body Added SYNONYM host cell coiled body
2010-12-17 GO:0072494 host multivesicular body Added SYNONYM host cell multivesicular body
2010-12-17 GO:0005759 mitochondrial matrix Added SYNONYM mitochondrial lumen
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in Wnt receptor signaling pathway through beta-catenin
2010-12-17 GO:0072495 host cell Cajal body Added SYNONYM coiled body of host
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in frizzled-1 receptor signaling pathway
2010-12-17 GO:0072499 photoreceptor cell axon guidance Added SYNONYM photoreceptor cell axon pathfinding
2010-12-17 GO:0060079 regulation of excitatory postsynaptic membrane potential Deleted SYNONYM EPSP
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in Wnt receptor signalling pathway through beta-catenin
2010-12-17 GO:0072496 Pup transferase activity Added SYNONYM Pup ligase activity
2010-12-17 GO:2000285 negative regulation of regulation of excitatory postsynaptic membrane potential Added SYNONYM negative regulation of EPSP
2010-12-17 GO:0072493 host cell endosome lumen Added SYNONYM host endosome lumen
2010-12-17 GO:0072496 Pup transferase activity Added SYNONYM Pup conjugating enzyme activity
2010-12-17 GO:0060079 regulation of excitatory postsynaptic membrane potential Added SYNONYM regulation of EPSP
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in canonical Wnt receptor signaling pathway
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in Wnt receptor signaling pathway via beta-catenin
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in canonical Wnt signaling pathway
2010-12-17 GO:0090394 negative regulation of excitatory postsynaptic membrane potential Added SYNONYM negative regulation of EPSP
2010-12-17 GO:0005759 mitochondrial matrix Added RELATION is a GO:0070013 (intracellular organelle lumen)
2010-12-17 GO:0005759 mitochondrial matrix Deleted RELATION part of GO:0031980 (mitochondrial lumen)
2010-12-17 GO:0031980 mitochondrial lumen Deleted XREF NIF_Subcellular:sao-1899375636
2010-12-17 GO:0005759 mitochondrial matrix Added XREF NIF_Subcellular:sao-1899375636
2010-12-17 GO:0031980 mitochondrial lumen Deleted RELATION is a GO:0070013 (intracellular organelle lumen)
2010-12-17 GO:0031980 mitochondrial lumen Deleted RELATION is a GO:0044429 (mitochondrial part)
2010-12-17 GO:0072037 mesenchymal stem cell differentiation involved in nephron morphogenesis Added RELATION is a GO:0072497 (mesenchymal stem cell differentiation)
2010-12-17 GO:0072037 mesenchymal stem cell differentiation involved in nephron morphogenesis Deleted RELATION is a GO:0048863 (stem cell differentiation)
2010-12-17 GO:0060272 embryonic skeletal joint morphogenesis Added RELATION part of GO:0072498 (embryonic skeletal joint development)
2010-12-17 GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation Added RELATION part of GO:0072497 (mesenchymal stem cell differentiation)
2010-12-17 GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation Deleted RELATION part of GO:0048863 (stem cell differentiation)
2010-12-17 GO:0072494 host multivesicular body Added RELATION is a GO:0044184 (host cell late endosome)
2010-12-17 GO:0072495 host cell Cajal body Added RELATION is a GO:0044094 (host cell nuclear part)
2010-12-17 GO:0072495 host cell Cajal body Added RELATION part of GO:0044095 (host cell nucleoplasm)
2010-12-17 GO:0072492 host cell mitochondrial intermembrane space Added RELATION is a GO:0033655 (host cell cytoplasm part)
2010-12-17 GO:0072492 host cell mitochondrial intermembrane space Added RELATION part of GO:0044190 (host cell mitochondrial envelope)
2010-12-17 GO:0072493 host cell endosome lumen Added RELATION part of GO:0044174 (host cell endosome)
2010-12-17 GO:0072493 host cell endosome lumen Added RELATION is a GO:0033655 (host cell cytoplasm part)
2010-12-17 GO:0090394 negative regulation of excitatory postsynaptic membrane potential Added RELATION is a GO:0060079 (regulation of excitatory postsynaptic membrane potential)
2010-12-17 GO:0090395 plant cell papilla Added RELATION is a GO:0042995 (cell projection)
2010-12-17 GO:0090396 leaf papilla Added RELATION is a GO:0090395 (plant cell papilla)
2010-12-17 GO:0090397 stigma papilla Added RELATION is a GO:0090395 (plant cell papilla)
2010-12-17 GO:0072496 Pup transferase activity Added RELATION is a GO:0019787 (ubiquitin-like protein transferase activity)
2010-12-17 GO:0072497 mesenchymal stem cell differentiation Added RELATION is a GO:0048863 (stem cell differentiation)
2010-12-17 GO:0090076 relaxation of skeletal muscle Added DEFINITION A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.
2010-12-17 GO:0090077 foam cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
2010-12-17 GO:0090104 pancreatic epsilon cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic E cell. A pancreatic E cell is a cell in the pancreas that secretes ghrelin.
2010-12-17 GO:0090122 cholesterol ester hydrolysis involved in cholesterol transport Added DEFINITION The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.
2010-12-17 GO:0090252 epithelium migration involved in imaginal disc-derived wing morphogenesis Added DEFINITION The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.
2010-12-17 GO:0090254 cell elongation involved in imaginal disc-derived wing morphogenesis Added DEFINITION The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.
2010-12-17 GO:0090336 positive regulation of brown fat cell differentiation Added DEFINITION Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
2010-12-17 GO:2000285 negative regulation of regulation of excitatory postsynaptic membrane potential Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of regulation of excitatory postsynaptic membrane potential.
2010-12-17 GO:0000706 meiotic DNA double-strand break processing Added DEFINITION The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.
2010-12-17 GO:0001754 eye photoreceptor cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.
2010-12-17 GO:0002099 tRNA wobble guanine modification Added DEFINITION The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
2010-12-17 GO:0090130 tissue migration Added DEFINITION The process in which the population of cells that make up a tissue undergo directed movement.
2010-12-17 GO:0090201 negative regulation of release of cytochrome c from mitochondria Added DEFINITION Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
2010-12-17 GO:0090260 negative regulation of retinal ganglion cell axon guidance Added DEFINITION Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
2010-12-17 GO:0090292 nuclear matrix anchoring at nuclear membrane Added DEFINITION The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.
2010-12-17 GO:0090297 positive regulation of mitochondrial DNA replication Added DEFINITION Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
2010-12-17 GO:0090387 phagolysosome assembly involved in apoptotic cell clearance Added DEFINITION The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.
2010-12-17 GO:0072171 mesonephric tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
2010-12-17 GO:0072173 metanephric tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.
2010-12-17 GO:0072186 metanephric cap morphogenesis Added DEFINITION The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
2010-12-17 GO:0072197 ureter morphogenesis Added DEFINITION The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.
2010-12-17 GO:0072209 metanephric mesangial cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0072242 metanephric DCT cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.
2010-12-17 GO:0072245 metanephric glomerular parietal epithelial cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
2010-12-17 GO:0072256 metanephric glomerular mesangial cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.
2010-12-17 GO:0072258 metanephric interstitial fibroblast differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0072325 vulval cell fate commitment Added DEFINITION The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
2010-12-17 GO:0072494 host multivesicular body Added DEFINITION A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.
2010-12-17 GO:0075015 formation of infection structure on or near host Added DEFINITION The process in which a symbiont structure that serves to infect the host is formed on or near its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075044 autophagy of host cells involved in interaction with symbiont Added DEFINITION The process in which the host cells digest parts of their own cytoplasm during interaction with its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075080 negative regulation by host of symbiont receptor-mediated signal transduction Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075082 positive regulation by host of symbiont transmembrane receptor-mediated signal transduction Added DEFINITION Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075087 modulation by host of symbiont G-protein coupled receptor protein signal transduction Added DEFINITION Any process in which the host organism modulates the frequency, rate or extent of the symbiont G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075092 negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075093 modulation by host of symbiont signal transduction mediated by G-protein beta subunit Added DEFINITION Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075095 negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075098 negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075103 modulation by host of symbiont calcium or calmodulin-mediated signal transduction Added DEFINITION Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075105 negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0022011 myelination in peripheral nervous system Added DEFINITION The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-17 GO:0022904 respiratory electron transport chain Added DEFINITION A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
2010-12-17 GO:0023022 termination of T cell signal transduction Added DEFINITION The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.
2010-12-17 GO:0023053 signal initiation by mechanical effect Added DEFINITION The process in which a mechanical signal causes activation of a receptor.
2010-12-17 GO:0023065 signal transmission via blood Added DEFINITION The process in which a signal is conveyed via blood.
2010-12-17 GO:0030316 osteoclast differentiation Added DEFINITION The process in which a relatively unspecialized monocyte acquires the specialized features of a osteoclast cell.
2010-12-17 GO:0031444 slow-twitch skeletal muscle fiber contraction Added DEFINITION A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
2010-12-17 GO:0034775 glutathione transmembrane transport Added DEFINITION A process in which glutathione is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0035051 cardiocyte differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
2010-12-17 GO:0042386 hemocyte differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
2010-12-17 GO:0042675 compound eye cone cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.
2010-12-17 GO:0042676 compound eye cone cell fate commitment Added DEFINITION The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.
2010-12-17 GO:0042705 ocellus photoreceptor cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.
2010-12-17 GO:0044011 single-species biofilm formation on inanimate substrate Added DEFINITION A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
2010-12-17 GO:0044407 single-species biofilm formation in or on host organism Added DEFINITION A process in which microorganisms of the same species attach to and grow in or on a surface in a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0048533 sporocyte differentiation Added DEFINITION The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.
2010-12-17 GO:0048889 neuromast support cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2010-12-17 GO:0050936 xanthophore differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.
2010-12-17 GO:0051078 meiotic nuclear envelope disassembly Added DEFINITION The cell cycle process in which the controlled breakdown of the nuclear envelope during meiotic cell division occurs.
2010-12-17 GO:0051146 striated muscle cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
2010-12-17 GO:0051255 spindle midzone assembly Added DEFINITION The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
2010-12-17 GO:0051755 meiotic sister chromatid arm separation Added DEFINITION The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.
2010-12-17 GO:0055047 generative cell mitosis Added DEFINITION The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.
2010-12-17 GO:0060020 Bergmann glial cell differentiation Added DEFINITION The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0060034 notochord cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
2010-12-17 GO:0075025 initiation of appressorium on or near host Deleted DEFINITION The process whereby a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0061130 pancreatic bud formation Deleted DEFINITION The morphogenetic process whereby the foregut region specified to become the pancreas forms a bud.
2010-12-17 GO:0031639 plasminogen activation Deleted DEFINITION The process whereby inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
2010-12-17 GO:0009913 epidermal cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.
2010-12-17 GO:0075107 positive regulation by symbiont of host adenylate cyclase activity Deleted DEFINITION Any process by which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075326 active spore dispersal on or near host Deleted DEFINITION Any active process by which a symbiont disseminates its spores, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0060448 dichotomous subdivision of terminal units involved in lung branching Deleted DEFINITION The process whereby a lung bud bifurcates.
2010-12-17 GO:0061252 mesonephric glomerular epithelial cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
2010-12-17 GO:0002244 hematopoietic progenitor cell differentiation Deleted DEFINITION The process whereby precursor cell type acquires the specialized features of a hemopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2010-12-17 GO:0050764 regulation of phagocytosis Deleted DEFINITION Any process that modulates the frequency, rate or extent of phagocytosis, the process whereby phagocytes engulf external particulate material.
2010-12-17 GO:0085018 maintenance of symbiont-containing vacuole by host Deleted DEFINITION The process by which a host organism maintains the structure and function of a symbiont-containing vacuole, mediated by a substance secreted by the host. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides.
2010-12-17 GO:0090131 mesenchyme migration Deleted DEFINITION The process by which the population of cells that make up a mesenchyme undergo directed movement.
2010-12-17 GO:0021878 forebrain astrocyte fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.
2010-12-17 GO:0060513 prostatic bud formation Added DEFINITION The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
2010-12-17 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis Added DEFINITION The process in which a branch forms along the side of a mammary duct.
2010-12-17 GO:0060705 neuron differentiation involved in salivary gland development Added DEFINITION The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.
2010-12-17 GO:0060843 venous endothelial cell differentiation Added DEFINITION The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.
2010-12-17 GO:0060932 His-Purkinje system cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.
2010-12-17 GO:0060935 cardiac fibroblast cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
2010-12-17 GO:0061102 stomach neuroendocrine cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.
2010-12-17 GO:0061252 mesonephric glomerular epithelial cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
2010-12-17 GO:0061329 Malpighian tubule principal cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.
2010-12-17 GO:0070306 lens fiber cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
2010-12-17 GO:0070308 lens fiber cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
2010-12-17 GO:0071422 succinate transmembrane transport Added DEFINITION A process in which a succinate ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0071990 maintenance of protein location in spindle pole body Added DEFINITION Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.
2010-12-17 GO:0072050 S-shaped body morphogenesis Added DEFINITION The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.
2010-12-17 GO:0072078 nephron tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
2010-12-17 GO:0072114 pronephros morphogenesis Added DEFINITION The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
2010-12-17 GO:0072134 nephrogenic mesenchyme morphogenesis Added DEFINITION The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
2010-12-17 GO:0072153 renal interstitial fibroblast fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal interstitial cell.
2010-12-17 GO:0072162 metanephric mesenchymal cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0002319 memory B cell differentiation Added DEFINITION The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.
2010-12-17 GO:0002327 immature B cell differentiation Added DEFINITION The process in which a precursor cell type acquires the specialized features of an immature B cell.
2010-12-17 GO:0002333 transitional one stage B cell differentiation Added DEFINITION The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.
2010-12-17 GO:0002338 B-1b B cell differentiation Added DEFINITION The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
2010-12-17 GO:0003092 renal water retention Added DEFINITION The process in which renal water excretion is decreased.
2010-12-17 GO:0003093 regulation of glomerular filtration Added DEFINITION Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
2010-12-17 GO:0006939 smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
2010-12-17 GO:0007060 male meiosis chromosome segregation Added DEFINITION The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.
2010-12-17 GO:0007079 mitotic chromosome movement towards spindle pole Added DEFINITION The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
2010-12-17 GO:0007091 metaphase/anaphase transition of mitotic cell cycle Added DEFINITION The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins.
2010-12-17 GO:0007460 R8 cell fate commitment Added DEFINITION The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium.
2010-12-17 GO:0007513 pericardial cell differentiation Added DEFINITION The process in which a relatively unspecialized mesodermal cell acquires the specialized features of a pericardial cell. In insects, pericardial cells are loosely arranged non-myogenic cells that flank the cardioblasts and probably act in the filtration of hemolymph.
2010-12-17 GO:0009559 embryo sac central cell differentiation Added DEFINITION The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell.
2010-12-17 GO:0009994 oocyte differentiation Added DEFINITION The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
2010-12-17 GO:0010002 cardioblast differentiation Added DEFINITION The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
2010-12-17 GO:0010773 meiotic DNA recombinase assembly involved in meiotic gene conversion Added DEFINITION The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
2010-12-17 GO:0010789 meiotic sister chromatid cohesion involved in meiosis I Added DEFINITION The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.
2010-12-17 GO:0010832 negative regulation of myotube differentiation Added DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Added DEFINITION Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0014008 positive regulation of microglia differentiation Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
2010-12-17 GO:0014016 neuroblast differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
2010-12-17 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Added DEFINITION The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0014818 skeletal muscle satellite cell fate determination Added DEFINITION The process in which a cell becomes capable of differentiating autonomously into a satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.
2010-12-17 GO:0014845 stomach body smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.
2010-12-17 GO:0014847 proximal stomach smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.
2010-12-17 GO:0014848 urinary tract smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.
2010-12-17 GO:0014902 myotube differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0021515 cell differentiation in spinal cord Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0021529 spinal cord oligodendrocyte cell differentiation Added DEFINITION The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0021709 cerebellar basket cell differentiation Added DEFINITION The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0021896 forebrain astrocyte differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
2010-12-17 GO:0090075 relaxation of muscle Added DEFINITION A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.
2010-12-17 GO:0030316 osteoclast differentiation Deleted DEFINITION The process whereby a relatively unspecialized monocyte acquires the specialized features of a osteoclast cell.
2010-12-17 GO:0070197 attachment of telomere to nuclear envelope Deleted DEFINITION The cell cycle process whereby physical connections are formed between telomeres and the nuclear envelope, facilitating bouquet formation.
2010-12-17 GO:0060531 neuroendocrine cell differentiation involved in prostate gland acinus development Deleted DEFINITION The process whereby relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.
2010-12-17 GO:0002329 pre-B cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
2010-12-17 GO:0021515 cell differentiation in spinal cord Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0023015 signal transduction by cis-phosphorylation Deleted DEFINITION The process whereby a signal is conveyed via the transfer of one or more phosphate groups by a kinase to a residue in the same kinase molecule.
2010-12-17 GO:0075239 zoospore formation Deleted DEFINITION The process by which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
2010-12-17 GO:0061102 stomach neuroendocrine cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.
2010-12-17 GO:0075043 maintenance of turgor in appressorium by melanization Deleted DEFINITION The process whereby melanin is produced in the appressorium of the symbiont on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0085032 modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade Deleted DEFINITION Any process by which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0010842 retina layer formation Deleted DEFINITION The process whereby the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
2010-12-17 GO:0045065 cytotoxic T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.
2010-12-17 GO:0048931 posterior lateral line nerve glial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.
2010-12-17 GO:0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Deleted DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.
2010-12-17 GO:0071825 protein-lipid complex subunit organization Deleted DEFINITION Any process by which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.
2010-12-17 GO:0048886 neuromast hair cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2010-12-17 GO:0071922 regulation of cohesin localization to chromatin Deleted DEFINITION Any process that modulates the frequency, rate or extent of a process by which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
2010-12-17 GO:0072147 glomerular parietal epithelial cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
2010-12-17 GO:0002296 T-helper 1 cell lineage commitment Deleted DEFINITION The process whereby a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.
2010-12-17 GO:0075333 positive regulation by host of symbiont adenylate cyclase-mediated signal transduction Deleted DEFINITION Any process by which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0003092 renal water retention Deleted DEFINITION The process whereby renal water excretion is decreased.
2010-12-17 GO:0043374 CD8-positive, alpha-beta T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
2010-12-17 GO:0075292 negative regulation of aplanospore formation Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process by which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
2010-12-17 GO:0071577 zinc II ion transmembrane transport Deleted DEFINITION A process whereby a zinc ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0000706 meiotic DNA double-strand break processing Deleted DEFINITION The cell cycle process whereby the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.
2010-12-17 GO:0075074 spore autophagy involved in appressorium formation on or near host Deleted DEFINITION The process by which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0061318 renal filtration cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0070574 cadmium ion transmembrane transport Deleted DEFINITION A process whereby a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0072134 nephrogenic mesenchyme morphogenesis Deleted DEFINITION The process by which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
2010-12-17 GO:0021994 progression of neural tube closure Deleted DEFINITION The process whereby the neural folds are fused extending from the initial closure points.
2010-12-17 GO:0021527 spinal cord association neuron differentiation Deleted DEFINITION The process whereby neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0002100 tRNA wobble adenosine to inosine editing Added DEFINITION The process in which an adenosine in position 34 of a tRNA is post-transcriptionally corverted to inosine.
2010-12-17 GO:0002292 T cell differentiation involved in immune response Added DEFINITION The process in which an antigenically nave T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2010-12-17 GO:0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Added DEFINITION The process in which an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.
2010-12-17 GO:0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation Added DEFINITION The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
2010-12-17 GO:0002313 mature B cell differentiation involved in immune response Added DEFINITION The process in which a nave B cell acquires the specialized features of a mature or memory B cell during an immune response.
2010-12-17 GO:0072295 specification of metanephric distal tubule identity Added DEFINITION The process in which the distal tubule of the metanephric nephron acquires its identity.
2010-12-17 GO:0072296 specification of metanephric loop of Henle identity Added DEFINITION The process in which the loop of Henle of the metanephric nephron acquires its identity.
2010-12-17 GO:0075262 negative regulation of spore-bearing organ development Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
2010-12-17 GO:0075270 negative regulation of aecium development Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0075287 positive regulation of sporangiospore formation Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
2010-12-17 GO:0085022 modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system Added DEFINITION The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0085025 modification by symbiont of host morphology or physiology via protein secreted by Tat complex Added DEFINITION The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072158 proximal tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
2010-12-17 GO:0072160 nephron tubule epithelial cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.
2010-12-17 GO:0070306 lens fiber cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
2010-12-17 GO:0085025 modification by symbiont of host morphology or physiology via protein secreted by Tat complex Deleted DEFINITION The process by which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090200 positive regulation of release of cytochrome c from mitochondria Deleted DEFINITION Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process by which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
2010-12-17 GO:0006887 exocytosis Deleted DEFINITION A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.
2010-12-17 GO:0090376 seed trichome differentiation Deleted DEFINITION The process whereby a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.
2010-12-17 GO:0075161 negative regulation of G-protein alpha subunit-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0035378 carbon dioxide transmembrane transport Deleted DEFINITION A process whereby carbon dioxide (CO2) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0048761 collenchyma cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.
2010-12-17 GO:0072273 metanephric nephron morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.
2010-12-17 GO:0034219 carbohydrate transmembrane transport Deleted DEFINITION The process whereby a carbohydrate is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0030859 polarized epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.
2010-12-17 GO:0045595 regulation of cell differentiation Deleted DEFINITION Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
2010-12-17 GO:0055085 transmembrane transport Deleted DEFINITION The process whereby a solute is transported from one side of a membrane to the other.
2010-12-17 GO:0090122 cholesterol ester hydrolysis involved in cholesterol transport Deleted DEFINITION The cholesterol metabolic process by which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.
2010-12-17 GO:0071918 urea transmembrane transport Deleted DEFINITION The process whereby urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0045143 homologous chromosome segregation Deleted DEFINITION The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
2010-12-17 GO:0060842 arterial endothelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.
2010-12-17 GO:0072325 vulval cell fate commitment Deleted DEFINITION The process by which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
2010-12-17 GO:0003348 cardiac endothelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
2010-12-17 GO:0061208 cell differentiation involved in mesonephros development Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.
2010-12-17 GO:0072311 glomerular epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
2010-12-17 GO:0061104 adrenal chromaffin cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.
2010-12-17 GO:0075173 negative regulation of MAP kinase-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090335 regulation of brown fat cell differentiation Deleted DEFINITION Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
2010-12-17 GO:0051317 attachment of spindle microtubules to meiotic chromosome Deleted DEFINITION The cell cycle process whereby spindle microtubules become physically associated with a chromosome during meiosis.
2010-12-17 GO:0003311 pancreatic D cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.
2010-12-17 GO:0075181 positive regulation of symbiont transcription in response to host Deleted DEFINITION Any process by which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075082 positive regulation by host of symbiont transmembrane receptor-mediated signal transduction Deleted DEFINITION Any process by which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0051146 striated muscle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
2010-12-17 GO:0001752 compound eye photoreceptor fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
2010-12-17 GO:0042492 gamma-delta T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.
2010-12-17 GO:0075126 negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit Deleted DEFINITION Any process by which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0035558 phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling Deleted DEFINITION The process whereby a signal is passed from the insulin receptor to components of the phosphoinositide 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2010-12-17 GO:0002306 CD4-positive gamma-delta intraepithelial T cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2010-12-17 GO:0071851 mitotic G1 cell cycle arrest in response to nitrogen starvation Deleted DEFINITION The process by which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.
2010-12-17 GO:0002326 B cell lineage commitment Deleted DEFINITION The process whereby a lymphoid progenitor cell becomes committed to become any type of B cell.
2010-12-17 GO:0032837 distributive segregation Deleted DEFINITION The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a "backup" mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally.
2010-12-17 GO:0072240 metanephric DCT cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0075269 positive regulation of aecium development Deleted DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process by which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0090173 regulation of synaptonemal complex assembly Deleted DEFINITION Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process whereby the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.
2010-12-17 GO:0075131 positive regulation by symbiont of host protein kinase-mediated signal transduction Deleted DEFINITION Any process by which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0043367 CD4-positive, alpha-beta T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.
2010-12-17 GO:0075304 negative regulation of basidiospore formation Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process by which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.
2010-12-17 GO:0010668 ectodermal cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0002317 plasma cell differentiation Deleted DEFINITION The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.
2010-12-17 GO:0023021 termination of signal transduction Deleted DEFINITION The signaling process whereby signal transduction is brought to an end rather than being reversibly modulated.
2010-12-17 GO:0042093 T-helper cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
2010-12-17 GO:0022010 central nervous system myelination Deleted DEFINITION The process whereby neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-17 GO:0075089 negative regulation by host of symbiont G-protein coupled receptor protein signal transduction Deleted DEFINITION Any process by which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075096 modulation by host of symbiont signal transduction mediated by G-protein gamma subunit Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0023070 signal transmission via air Deleted DEFINITION The process whereby a signal is conveyed via the air.
2010-12-17 GO:0006939 smooth muscle contraction Deleted DEFINITION A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
2010-12-17 GO:0071830 triglyceride-rich lipoprotein particle clearance Deleted DEFINITION The process by which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
2010-12-17 GO:0072284 metanephric S-shaped body morphogenesis Deleted DEFINITION The process by which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.
2010-12-17 GO:0048533 sporocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.
2010-12-17 GO:0045444 fat cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
2010-12-17 GO:0002303 gamma-delta T cell differentiation involved in immune response Deleted DEFINITION The process whereby an antigenically nave gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2010-12-17 GO:0023017 signal transmission via diffusible molecule Deleted DEFINITION The process whereby a signal is conveyed via a diffusible molecule.
2010-12-17 GO:0007520 myoblast fusion Deleted DEFINITION A process whereby non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2010-12-17 GO:0021520 spinal cord motor neuron cell fate specification Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
2010-12-17 GO:0014007 negative regulation of microglia differentiation Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell.
2010-12-17 GO:0075133 modulation by symbiont of host calcium or calmodulin-mediated signal transduction Deleted DEFINITION Any process by which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072077 renal vesicle morphogenesis Deleted DEFINITION The process by which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
2010-12-17 GO:0072327 vulval cell fate specification Deleted DEFINITION The process by which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
2010-12-17 GO:0023054 signal initiation by stretch effect Deleted DEFINITION The process whereby a stretch signal causes activation of a receptor.
2010-12-17 GO:0042707 ocellus photoreceptor cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
2010-12-17 GO:0010755 regulation of plasminogen activation Deleted DEFINITION Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin.
2010-12-17 GO:0001742 oenocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.
2010-12-17 GO:0050935 iridophore differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.
2010-12-17 GO:0031443 fast-twitch skeletal muscle fiber contraction Deleted DEFINITION A process whereby force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.
2010-12-17 GO:0072197 ureter morphogenesis Deleted DEFINITION The process by which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.
2010-12-17 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway Deleted DEFINITION The process whereby an epidermal growth factor receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGFR and GPCR signaling pathways.
2010-12-17 GO:0003361 noradrenergic neuron differentiation involved in brainstem development Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.
2010-12-17 GO:0060014 granulosa cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.
2010-12-17 GO:0075058 modulation of symbiont penetration peg initiation Deleted DEFINITION Any process that modulates the frequency, rate or extent of penetration peg initiation, the process whereby a relatively unspecialized cell start to acquire the characteristics of a mature penetration peg when the symbiont penetrates its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090132 epithelium migration Deleted DEFINITION The process by which the population of cells that make up an epithelium undergo directed movement.
2010-12-17 GO:0048865 stem cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a stem cell.
2010-12-17 GO:0060946 cardiac blood vessel endothelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.
2010-12-17 GO:0075016 appressorium formation on or near host Deleted DEFINITION The process by which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075241 positive regulation of zoospore formation Deleted DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process by which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
2010-12-17 GO:0075156 regulation of G-protein coupled receptor protein signaling pathway in response to host Deleted DEFINITION Any process by which the symbiont organism modulates the frequency, rate or extent of its G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0051891 positive regulation of cardioblast differentiation Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
2010-12-17 GO:0048863 stem cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
2010-12-17 GO:0060034 notochord cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
2010-12-17 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
2010-12-17 GO:0060486 Clara cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a Clara cell. A Clara cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.
2010-12-17 GO:0060891 limb granular cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.
2010-12-17 GO:0010745 negative regulation of macrophage derived foam cell differentiation Deleted DEFINITION Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process whereby a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
2010-12-17 GO:0010055 atrichoblast differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.
2010-12-17 GO:0002067 glandular epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
2010-12-17 GO:0023052 signaling Deleted DEFINITION The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.
2010-12-17 GO:0090260 negative regulation of retinal ganglion cell axon guidance Deleted DEFINITION Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process by which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
2010-12-17 GO:0042706 eye photoreceptor cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
2010-12-17 GO:0021528 commissural neuron differentiation in spinal cord Deleted DEFINITION The process whereby neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0014839 myoblast migration involved in skeletal muscle regeneration Deleted DEFINITION The process whereby a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2010-12-17 GO:0075210 negative regulation by symbiont of host cAMP-mediated signal transduction Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0002136 wobble base lysidine biosynthesis Deleted DEFINITION The process whereby the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.
2010-12-17 GO:0075157 positive regulation of G-protein coupled receptor protein signaling pathway in response to host Deleted DEFINITION Any process by which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0014847 proximal stomach smooth muscle contraction Deleted DEFINITION A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.
2010-12-17 GO:0061319 nephrocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is a renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0021711 cerebellar unipolar brush cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0051756 meiotic sister chromatid centromere separation Deleted DEFINITION The cell cycle process whereby the centromeres of sister chromatids are physically detached from each other during meiosis.
2010-12-17 GO:0050934 late stripe melanocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).
2010-12-17 GO:0002574 thrombocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.
2010-12-17 GO:0023060 signal transmission Deleted DEFINITION The process whereby a signal is released and/or conveyed from one location to another.
2010-12-17 GO:0001949 sebaceous gland cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.
2010-12-17 GO:0007129 synapsis Deleted DEFINITION The cell cycle process whereby the side by side pairing and physical juxtaposition of homologous chromosomes is created at the metaphase plate.
2010-12-17 GO:0080170 hydrogen peroxide transmembrane transport Deleted DEFINITION The process whereby hydrogen peroxide is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.
2010-12-17 GO:0035555 initiation of Roundabout signal transduction Deleted DEFINITION The process whereby a SLIT protein causes activation of the receptor, Roundabout (ROBO).
2010-12-17 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Deleted DEFINITION Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process whereby the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0014813 skeletal muscle satellite cell commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.
2010-12-17 GO:0033260 nuclear DNA replication Deleted DEFINITION The process whereby new strands of genomic DNA are synthesized, using parental DNA as a template for DNA-dependent DNA polymerases, contributing to progression through S phase of the cell cycle.
2010-12-17 GO:0023022 termination of T cell signal transduction Deleted DEFINITION The signaling process whereby T cell signal transduction is brought to an end rather than being reversibly modulated.
2010-12-17 GO:0060942 neural crest-derived cardiac fibroblast cell differentiation Deleted DEFINITION The process whereby a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
2010-12-17 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Deleted DEFINITION The process whereby the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response Deleted DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2010-12-17 GO:0007165 signal transduction Deleted DEFINITION The process whereby a signal is converted into a form where it can ultimately trigger a change in the state or activity of a cell. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
2010-12-17 GO:0002318 myeloid progenitor cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
2010-12-17 GO:0072186 metanephric cap morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
2010-12-17 GO:0071896 protein localization to adherens junction Deleted DEFINITION Any process by which a protein is transported to, and/or maintained at the adherens junction.
2010-12-17 GO:0015030 Cajal body Deleted DEFINITION A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
2010-12-17 GO:0031149 sorocarp stalk cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.
2010-12-17 GO:0051078 meiotic nuclear envelope disassembly Deleted DEFINITION The cell cycle process whereby the controlled breakdown of the nuclear envelope during meiotic cell division occurs.
2010-12-17 GO:0075080 negative regulation by host of symbiont receptor-mediated signal transduction Deleted DEFINITION Any process by which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0048888 neuromast mantle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2010-12-17 GO:0075059 positive regulation of symbiont penetration peg initiation Deleted DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg initiation, the process whereby a relatively unspecialized cell starts to acquire the characteristics of a mature penetration peg during the symbiont penetrating into its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075183 infection cushion formation on or near host Deleted DEFINITION The process by which an organized mass of hyphae is formed on or near the host organism, and numerous infective hyphae develop from the hyphae mass. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090259 regulation of retinal ganglion cell axon guidance Deleted DEFINITION Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process by which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
2010-12-17 GO:0050933 early stripe melanocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).
2010-12-17 GO:0031980 mitochondrial lumen Deleted DEFINITION The volume enclosed by the mitochondrial inner membrane.
2010-12-17 GO:0072071 kidney interstitial fibroblast differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the kidney as it progresses from its formation to the mature state.
2010-12-17 GO:0072188 metanephric cap specification Deleted DEFINITION The process by which the metanephric cap acquires its identity.
2010-12-17 GO:0007130 synaptonemal complex assembly Deleted DEFINITION The cell cycle process whereby the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
2010-12-17 GO:0023009 initiation of T cell receptor signaling Deleted DEFINITION The process whereby a signal causes activation of T cell receptor signaling.
2010-12-17 GO:0072283 metanephric renal vesicle morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.
2010-12-17 GO:0072139 glomerular parietal epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
2010-12-17 GO:0002099 tRNA wobble guanine modification Deleted DEFINITION The process whereby a guanine in t position 34 of a tRNA is post-transcriptionally modified.
2010-12-17 GO:0075093 modulation by host of symbiont signal transduction mediated by G-protein beta subunit Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072028 nephron morphogenesis Deleted DEFINITION The process by which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.
2010-12-17 GO:0060679 trifid subdivision of terminal units involved in ureteric bud branching Deleted DEFINITION The process whereby a ureteric bud splits into three units at its end.
2010-12-17 GO:0035559 MAPKKK cascade involved in epidermal growth factor receptor signaling Deleted DEFINITION The process whereby a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2010-12-17 GO:0060629 regulation of homologous chromosome segregation Deleted DEFINITION Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
2010-12-17 GO:0021702 cerebellar Purkinje cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
2010-12-17 GO:0030154 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0030221 basophil differentiation Deleted DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.
2010-12-17 GO:0030216 keratinocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a keratinocyte.
2010-12-17 GO:0001923 B-1 B cell differentiation Deleted DEFINITION The process whereby a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
2010-12-17 GO:0022011 myelination in peripheral nervous system Deleted DEFINITION The process whereby neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-17 GO:0042490 mechanoreceptor differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.
2010-12-17 GO:0002328 pro-B cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
2010-12-17 GO:0070588 calcium ion transmembrane transport Deleted DEFINITION A process whereby a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0075207 negative regulation by host of symbiont cAMP-mediated signal transduction Deleted DEFINITION Any process by which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0060431 primary lung bud formation Deleted DEFINITION The morphogenetic process whereby the foregut region specified to become the lung forms the initial left and right buds.
2010-12-17 GO:0030989 dynein-driven meiotic oscillatory nuclear movement Deleted DEFINITION The cell cycle process whereby oscillatory movement of the nucleus during meiotic prophase I occurs. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein. It is known to play a central role in meiotic recombination and homologous chromosome pairing; as observed in S. pombe.
2010-12-17 GO:0014830 arteriole smooth muscle contraction Deleted DEFINITION A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.
2010-12-17 GO:0048052 R1/R6 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.
2010-12-17 GO:0090252 epithelium migration involved in imaginal disc-derived wing morphogenesis Deleted DEFINITION The process by which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.
2010-12-17 GO:0072258 metanephric interstitial fibroblast differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0060610 mesenchymal cell differentiation involved in mammary gland development Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.
2010-12-17 GO:0060707 trophoblast giant cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.
2010-12-17 GO:0010789 meiotic sister chromatid cohesion involved in meiosis I Deleted DEFINITION The cell cycle process whereby sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.
2010-12-17 GO:0010520 regulation of reciprocal meiotic recombination Deleted DEFINITION Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate.
2010-12-17 GO:0048333 mesodermal cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
2010-12-17 GO:0007131 reciprocal meiotic recombination Deleted DEFINITION The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
2010-12-17 GO:0035624 receptor transactivation Deleted DEFINITION The process whereby a receptor is activated via signaling events from a receptor for a different ligand. Receptor transactivation is an example of cross-talk between signaling pathways and can occur through several different mechanisms.
2010-12-17 GO:0045446 endothelial cell differentiation Deleted DEFINITION The process whereby a mesodermal angioblast acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
2010-12-17 GO:0023006 signal initiation by amino acid Deleted DEFINITION The process whereby an amino acid signal causes activation of a receptor.
2010-12-17 GO:0075335 positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0032121 attachment of telomeric heterochromatin to spindle pole body Deleted DEFINITION The cell cycle process whereby physical connections are formed between telomeres and the spindle pole body, facilitating bouquet formation.
2010-12-17 GO:0048908 anterior lateral line ganglion neuron differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.
2010-12-17 GO:0002284 myeloid dendritic cell differentiation involved in immune response Deleted DEFINITION The process whereby an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.
2010-12-17 GO:0060709 glycogen cell differentiation involved in embryonic placenta development Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.
2010-12-17 GO:0072131 kidney mesenchyme morphogenesis Deleted DEFINITION The process by which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.
2010-12-17 GO:0021526 medial motor column neuron differentiation Deleted DEFINITION The process whereby differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0075176 negative regulation of cAMP-mediated signaling in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072173 metanephric tubule morphogenesis Deleted DEFINITION The process by which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.
2010-12-17 GO:0072282 metanephric nephron tubule morphogenesis Deleted DEFINITION The process by which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.
2010-12-17 GO:0072082 specification of proximal tubule identity Deleted DEFINITION The process by which the proximal tubule of the kidney nephron acquires its identity.
2010-12-17 GO:0006311 meiotic gene conversion Deleted DEFINITION The cell cycle process whereby genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele.
2010-12-17 GO:0010832 negative regulation of myotube differentiation Deleted DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0002338 B-1b B cell differentiation Deleted DEFINITION The process whereby B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
2010-12-17 GO:0010773 meiotic DNA recombinase assembly involved in meiotic gene conversion Deleted DEFINITION The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process whereby genetic information is transferred from one helix to another.
2010-12-17 GO:0060375 regulation of mast cell differentiation Deleted DEFINITION Any process that modulates the rate, frequency or extent of mast cell differentiation, the process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
2010-12-17 GO:0090033 positive regulation of filamentous growth Deleted DEFINITION Any process that increases the frequency, rate or extent of the process by which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2010-12-17 GO:0048928 posterior lateral line ganglion neuron differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.
2010-12-17 GO:0061322 disseminated nephrocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is a renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0007079 mitotic chromosome movement towards spindle pole Deleted DEFINITION The cell cycle process whereby the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
2010-12-17 GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development Deleted DEFINITION The process whereby a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.
2010-12-17 GO:0060920 cardiac pacemaker cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
2010-12-17 GO:0072086 specification of loop of Henle identity Deleted DEFINITION The process by which the loop of Henle of the kidney nephron acquires its identity.
2010-12-17 GO:0048235 pollen sperm cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.
2010-12-17 GO:0023068 signal transmission via phloem Deleted DEFINITION The process whereby a signal is conveyed via the phloem.
2010-12-17 GO:0090103 cochlea morphogenesis Deleted DEFINITION The process by which the cochlea is generated and organized.
2010-12-17 GO:0002316 follicular B cell differentiation Deleted DEFINITION The process whereby a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
2010-12-17 GO:0007464 R3/R4 cell fate commitment Deleted DEFINITION The process whereby the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.
2010-12-17 GO:0009563 synergid differentiation Deleted DEFINITION The process whereby an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell.
2010-12-17 GO:0090076 relaxation of skeletal muscle Deleted DEFINITION A process whereby the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.
2010-12-17 GO:0075103 modulation by host of symbiont calcium or calmodulin-mediated signal transduction Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0035051 cardiocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
2010-12-17 GO:0023019 signal transduction involved in regulation of gene expression Deleted DEFINITION Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process whereby a signal is released and/or conveyed from one location to another.
2010-12-17 GO:0075152 negative regulation of receptor-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072052 juxtaglomerulus cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.
2010-12-17 GO:0009920 cell plate formation involved in plant-type cell wall biogenesis Deleted DEFINITION The cell cycle process whereby the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.
2010-12-17 GO:0002297 T-helper 2 cell lineage commitment Deleted DEFINITION The process whereby a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.
2010-12-17 GO:0030224 monocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
2010-12-17 GO:0001829 trophectodermal cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.
2010-12-17 GO:0075174 regulation of cAMP-mediated signaling in response to host Deleted DEFINITION Any process by which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075268 regulation of aecium development Deleted DEFINITION Any process that modulates the frequency, rate or extent of aecium development, a process by which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0090199 regulation of release of cytochrome c from mitochondria Deleted DEFINITION Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process by which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
2010-12-17 GO:0048772 leucophore differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.
2010-12-17 GO:0003362 noradrenergic neuron fate commitment involved in brainstem development Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem.
2010-12-17 GO:0075290 regulation of aplanospore formation Deleted DEFINITION Any process that modulates the frequency, rate or extent of aplanospore formation, a process by which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
2010-12-17 GO:0035168 larval lymph gland hemocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.
2010-12-17 GO:0048759 xylem vessel member cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.
2010-12-17 GO:0023020 regulation of gene expression as a consequence of T cell signal transmission Deleted DEFINITION Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process whereby a T cell signal is released and/or conveyed from one location to another.
2010-12-17 GO:0061266 mesonephric interstitial fibroblast differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the mesonephros as it progresses from its formation to the mature state.
2010-12-17 GO:0051295 establishment of meiotic spindle localization Deleted DEFINITION The cell cycle process whereby the directed movement of the meiotic spindle to a specific location in the cell occurs.
2010-12-17 GO:0048056 R3/R4 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.
2010-12-17 GO:0007098 centrosome cycle Deleted DEFINITION The cell cycle process whereby centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
2010-12-17 GO:0002272 plasmacytoid dendritic cell differentiation involved in immune response Deleted DEFINITION The process whereby an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response.
2010-12-17 GO:0021997 neural plate axis specification Deleted DEFINITION The pattern specification process whereby the axes of the nervous system are established.
2010-12-17 GO:0072275 metanephric glomerulus morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
2010-12-17 GO:0072196 proximal/distal pattern formation involved in pronephric nephron development Deleted DEFINITION The regionalization process by which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.
2010-12-17 GO:0055011 atrial cardiac muscle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.
2010-12-17 GO:0035349 coenzyme A transmembrane transport Deleted DEFINITION The process whereby coenzyme A is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
2010-12-17 GO:0007343 egg activation Deleted DEFINITION The process whereby the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.
2010-12-17 GO:0010830 regulation of myotube differentiation Deleted DEFINITION Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0003011 involuntary skeletal muscle contraction Deleted DEFINITION A process whereby force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.
2010-12-17 GO:0010002 cardioblast differentiation Deleted DEFINITION The process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
2010-12-17 GO:0031134 sister chromatid biorientation Deleted DEFINITION The cell cycle process whereby sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
2010-12-17 GO:0010775 meiotic strand invasion involved in meiotic gene conversion Deleted DEFINITION The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.
2010-12-17 GO:0021709 cerebellar basket cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0061259 mesonephric glomerular mesangial cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.
2010-12-17 GO:0021707 cerebellar granule cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0071421 manganese ion transmembrane transport Deleted DEFINITION A process whereby a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0021514 ventral spinal cord interneuron differentiation Deleted DEFINITION The process whereby neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0072315 metanephric glomerular epithelial cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
2010-12-17 GO:0075191 autophagy of host cells on or near symbiont surface Deleted DEFINITION The process by which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0061268 mesonephric interstitial fibroblast fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial cell.
2010-12-17 GO:0060580 ventral spinal cord interneuron fate determination Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.
2010-12-17 GO:0014902 myotube differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0001826 inner cell mass cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an inner cell mass cell.
2010-12-17 GO:0060490 lateral sprouting involved in lung morphogenesis Deleted DEFINITION The process whereby a branch forms along the side of the lung epithelial tube.
2010-12-17 GO:0000708 meiotic strand invasion Deleted DEFINITION The cell cycle process whereby the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.
2010-12-17 GO:0023045 signal transduction by conformational transition Deleted DEFINITION The process whereby a signal is conveyed via a conformational transition.
2010-12-17 GO:0003167 atrioventricular bundle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.
2010-12-17 GO:0045128 negative regulation of reciprocal meiotic recombination Deleted DEFINITION Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate.
2010-12-17 GO:0075166 positive regulation of G-protein gamma subunit-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0045064 T-helper 2 cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a Th2 cell.
2010-12-17 GO:0031444 slow-twitch skeletal muscle fiber contraction Deleted DEFINITION A process whereby force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
2010-12-17 GO:0090297 positive regulation of mitochondrial DNA replication Deleted DEFINITION Any process that increases the rate, frequency or extent of the process whereby new strands of DNA are synthesized in the mitochondrion.
2010-12-17 GO:0060836 lymphatic endothelial cell differentiation Deleted DEFINITION The process whereby a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.
2010-12-17 GO:0075081 modulation by host of symbiont transmembrane receptor-mediated signal transduction Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0048913 anterior lateral line nerve glial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.
2010-12-17 GO:0014818 skeletal muscle satellite cell fate determination Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.
2010-12-17 GO:0051231 spindle elongation Deleted DEFINITION The cell cycle process whereby the distance is lengthened between poles of the spindle.
2010-12-17 GO:0048866 stem cell fate specification Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
2010-12-17 GO:0055119 relaxation of cardiac muscle Deleted DEFINITION The process whereby the extent of cardiac muscle contraction is reduced.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2010-12-17 GO:0060113 inner ear receptor cell differentiation Added DEFINITION The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.
2010-12-17 GO:0060219 camera-type eye photoreceptor cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
2010-12-17 GO:0060222 regulation of retinal cone cell fate commitment Added DEFINITION Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
2010-12-17 GO:0060223 retinal rod cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2010-12-17 GO:0060374 mast cell differentiation Added DEFINITION The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
2010-12-17 GO:0060503 bud dilation involved in lung branching Added DEFINITION The process in which a bud in the lung increases radially.
2010-12-17 GO:0075114 negative regulation by symbiont of host transmembrane receptor-mediated signal transduction Added DEFINITION Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075158 negative regulation of G-protein coupled receptor protein signaling pathway in response to host Added DEFINITION Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075162 regulation of G-protein beta subunit-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075163 positive regulation of G-protein beta subunit-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075169 positive regulation of symbiont protein kinase-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075173 negative regulation of MAP kinase-mediated signal transduction in response to host Added DEFINITION Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075180 regulation of transcription in response to host Added DEFINITION Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075187 hyphopodium formation on or near host Added DEFINITION The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075250 negative regulation of aeciospore formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
2010-12-17 GO:0075268 regulation of aecium development Added DEFINITION Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0075269 positive regulation of aecium development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0075273 positive regulation of zygosporangium development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
2010-12-17 GO:0075288 negative regulation of sporangiospore formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
2010-12-17 GO:0075298 regulation of zygospore formation Added DEFINITION Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
2010-12-17 GO:0085044 disassembly by symbiont of host cuticle Added DEFINITION The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090112 COPII vesicle uncoating Added DEFINITION The process in which COPII vesicle coat proteins are disassembled, and released.
2010-12-17 GO:0072495 host cell Cajal body Added SYNONYM host cell coiled body
2010-12-17 GO:0072494 host multivesicular body Added SYNONYM host cell multivesicular body
2010-12-17 GO:0005759 mitochondrial matrix Added SYNONYM mitochondrial lumen
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in Wnt receptor signaling pathway through beta-catenin
2010-12-17 GO:0072495 host cell Cajal body Added SYNONYM coiled body of host
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in frizzled-1 receptor signaling pathway
2010-12-17 GO:0072499 photoreceptor cell axon guidance Added SYNONYM photoreceptor cell axon pathfinding
2010-12-17 GO:0060079 regulation of excitatory postsynaptic membrane potential Deleted SYNONYM EPSP
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in Wnt receptor signalling pathway through beta-catenin
2010-12-17 GO:0072496 Pup transferase activity Added SYNONYM Pup ligase activity
2010-12-17 GO:2000285 negative regulation of regulation of excitatory postsynaptic membrane potential Added SYNONYM negative regulation of EPSP
2010-12-17 GO:0072493 host cell endosome lumen Added SYNONYM host endosome lumen
2010-12-17 GO:0072496 Pup transferase activity Added SYNONYM Pup conjugating enzyme activity
2010-12-17 GO:0060079 regulation of excitatory postsynaptic membrane potential Added SYNONYM regulation of EPSP
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in canonical Wnt receptor signaling pathway
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in Wnt receptor signaling pathway via beta-catenin
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added SYNONYM receptor internalization involved in canonical Wnt signaling pathway
2010-12-17 GO:0090394 negative regulation of excitatory postsynaptic membrane potential Added SYNONYM negative regulation of EPSP
2010-12-17 GO:0090076 relaxation of skeletal muscle Added DEFINITION A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.
2010-12-17 GO:0090077 foam cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
2010-12-17 GO:0090104 pancreatic epsilon cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic E cell. A pancreatic E cell is a cell in the pancreas that secretes ghrelin.
2010-12-17 GO:0090122 cholesterol ester hydrolysis involved in cholesterol transport Added DEFINITION The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.
2010-12-17 GO:0090252 epithelium migration involved in imaginal disc-derived wing morphogenesis Added DEFINITION The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.
2010-12-17 GO:0090254 cell elongation involved in imaginal disc-derived wing morphogenesis Added DEFINITION The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.
2010-12-17 GO:0090336 positive regulation of brown fat cell differentiation Added DEFINITION Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
2010-12-17 GO:2000285 negative regulation of regulation of excitatory postsynaptic membrane potential Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of regulation of excitatory postsynaptic membrane potential.
2010-12-17 GO:0000706 meiotic DNA double-strand break processing Added DEFINITION The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.
2010-12-17 GO:0001754 eye photoreceptor cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.
2010-12-17 GO:0002099 tRNA wobble guanine modification Added DEFINITION The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
2010-12-17 GO:0090130 tissue migration Added DEFINITION The process in which the population of cells that make up a tissue undergo directed movement.
2010-12-17 GO:0090201 negative regulation of release of cytochrome c from mitochondria Added DEFINITION Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
2010-12-17 GO:0090260 negative regulation of retinal ganglion cell axon guidance Added DEFINITION Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
2010-12-17 GO:0090292 nuclear matrix anchoring at nuclear membrane Added DEFINITION The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.
2010-12-17 GO:0090297 positive regulation of mitochondrial DNA replication Added DEFINITION Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
2010-12-17 GO:0090387 phagolysosome assembly involved in apoptotic cell clearance Added DEFINITION The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.
2010-12-17 GO:0072171 mesonephric tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
2010-12-17 GO:0072173 metanephric tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.
2010-12-17 GO:0072186 metanephric cap morphogenesis Added DEFINITION The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
2010-12-17 GO:0072197 ureter morphogenesis Added DEFINITION The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.
2010-12-17 GO:0072209 metanephric mesangial cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0072242 metanephric DCT cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.
2010-12-17 GO:0072245 metanephric glomerular parietal epithelial cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
2010-12-17 GO:0072256 metanephric glomerular mesangial cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.
2010-12-17 GO:0072258 metanephric interstitial fibroblast differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0072325 vulval cell fate commitment Added DEFINITION The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
2010-12-17 GO:0072494 host multivesicular body Added DEFINITION A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.
2010-12-17 GO:0075015 formation of infection structure on or near host Added DEFINITION The process in which a symbiont structure that serves to infect the host is formed on or near its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075044 autophagy of host cells involved in interaction with symbiont Added DEFINITION The process in which the host cells digest parts of their own cytoplasm during interaction with its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075080 negative regulation by host of symbiont receptor-mediated signal transduction Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075082 positive regulation by host of symbiont transmembrane receptor-mediated signal transduction Added DEFINITION Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075087 modulation by host of symbiont G-protein coupled receptor protein signal transduction Added DEFINITION Any process in which the host organism modulates the frequency, rate or extent of the symbiont G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075092 negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075093 modulation by host of symbiont signal transduction mediated by G-protein beta subunit Added DEFINITION Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075095 negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075098 negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075103 modulation by host of symbiont calcium or calmodulin-mediated signal transduction Added DEFINITION Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075105 negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction Added DEFINITION Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0022011 myelination in peripheral nervous system Added DEFINITION The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-17 GO:0022904 respiratory electron transport chain Added DEFINITION A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
2010-12-17 GO:0023022 termination of T cell signal transduction Added DEFINITION The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.
2010-12-17 GO:0023053 signal initiation by mechanical effect Added DEFINITION The process in which a mechanical signal causes activation of a receptor.
2010-12-17 GO:0023065 signal transmission via blood Added DEFINITION The process in which a signal is conveyed via blood.
2010-12-17 GO:0030316 osteoclast differentiation Added DEFINITION The process in which a relatively unspecialized monocyte acquires the specialized features of a osteoclast cell.
2010-12-17 GO:0031444 slow-twitch skeletal muscle fiber contraction Added DEFINITION A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
2010-12-17 GO:0034775 glutathione transmembrane transport Added DEFINITION A process in which glutathione is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0035051 cardiocyte differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
2010-12-17 GO:0042386 hemocyte differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
2010-12-17 GO:0042675 compound eye cone cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.
2010-12-17 GO:0042676 compound eye cone cell fate commitment Added DEFINITION The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.
2010-12-17 GO:0042705 ocellus photoreceptor cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.
2010-12-17 GO:0044011 single-species biofilm formation on inanimate substrate Added DEFINITION A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
2010-12-17 GO:0044407 single-species biofilm formation in or on host organism Added DEFINITION A process in which microorganisms of the same species attach to and grow in or on a surface in a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0048533 sporocyte differentiation Added DEFINITION The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.
2010-12-17 GO:0048889 neuromast support cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2010-12-17 GO:0050936 xanthophore differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.
2010-12-17 GO:0051078 meiotic nuclear envelope disassembly Added DEFINITION The cell cycle process in which the controlled breakdown of the nuclear envelope during meiotic cell division occurs.
2010-12-17 GO:0051146 striated muscle cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
2010-12-17 GO:0051255 spindle midzone assembly Added DEFINITION The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
2010-12-17 GO:0051755 meiotic sister chromatid arm separation Added DEFINITION The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.
2010-12-17 GO:0055047 generative cell mitosis Added DEFINITION The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.
2010-12-17 GO:0060020 Bergmann glial cell differentiation Added DEFINITION The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0060034 notochord cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
2010-12-17 GO:0075025 initiation of appressorium on or near host Deleted DEFINITION The process whereby a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0061130 pancreatic bud formation Deleted DEFINITION The morphogenetic process whereby the foregut region specified to become the pancreas forms a bud.
2010-12-17 GO:0031639 plasminogen activation Deleted DEFINITION The process whereby inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
2010-12-17 GO:0009913 epidermal cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.
2010-12-17 GO:0075107 positive regulation by symbiont of host adenylate cyclase activity Deleted DEFINITION Any process by which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075326 active spore dispersal on or near host Deleted DEFINITION Any active process by which a symbiont disseminates its spores, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0060448 dichotomous subdivision of terminal units involved in lung branching Deleted DEFINITION The process whereby a lung bud bifurcates.
2010-12-17 GO:0061252 mesonephric glomerular epithelial cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
2010-12-17 GO:0002244 hematopoietic progenitor cell differentiation Deleted DEFINITION The process whereby precursor cell type acquires the specialized features of a hemopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2010-12-17 GO:0050764 regulation of phagocytosis Deleted DEFINITION Any process that modulates the frequency, rate or extent of phagocytosis, the process whereby phagocytes engulf external particulate material.
2010-12-17 GO:0085018 maintenance of symbiont-containing vacuole by host Deleted DEFINITION The process by which a host organism maintains the structure and function of a symbiont-containing vacuole, mediated by a substance secreted by the host. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides.
2010-12-17 GO:0090131 mesenchyme migration Deleted DEFINITION The process by which the population of cells that make up a mesenchyme undergo directed movement.
2010-12-17 GO:0021878 forebrain astrocyte fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.
2010-12-17 GO:0060513 prostatic bud formation Added DEFINITION The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
2010-12-17 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis Added DEFINITION The process in which a branch forms along the side of a mammary duct.
2010-12-17 GO:0060705 neuron differentiation involved in salivary gland development Added DEFINITION The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.
2010-12-17 GO:0060843 venous endothelial cell differentiation Added DEFINITION The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.
2010-12-17 GO:0060932 His-Purkinje system cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.
2010-12-17 GO:0060935 cardiac fibroblast cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
2010-12-17 GO:0061102 stomach neuroendocrine cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.
2010-12-17 GO:0061252 mesonephric glomerular epithelial cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
2010-12-17 GO:0061329 Malpighian tubule principal cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.
2010-12-17 GO:0070306 lens fiber cell differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
2010-12-17 GO:0070308 lens fiber cell fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
2010-12-17 GO:0071422 succinate transmembrane transport Added DEFINITION A process in which a succinate ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0071990 maintenance of protein location in spindle pole body Added DEFINITION Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.
2010-12-17 GO:0072050 S-shaped body morphogenesis Added DEFINITION The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.
2010-12-17 GO:0072078 nephron tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
2010-12-17 GO:0072114 pronephros morphogenesis Added DEFINITION The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
2010-12-17 GO:0072134 nephrogenic mesenchyme morphogenesis Added DEFINITION The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
2010-12-17 GO:0072153 renal interstitial fibroblast fate commitment Added DEFINITION The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal interstitial cell.
2010-12-17 GO:0072162 metanephric mesenchymal cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0002319 memory B cell differentiation Added DEFINITION The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.
2010-12-17 GO:0002327 immature B cell differentiation Added DEFINITION The process in which a precursor cell type acquires the specialized features of an immature B cell.
2010-12-17 GO:0002333 transitional one stage B cell differentiation Added DEFINITION The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.
2010-12-17 GO:0002338 B-1b B cell differentiation Added DEFINITION The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
2010-12-17 GO:0003092 renal water retention Added DEFINITION The process in which renal water excretion is decreased.
2010-12-17 GO:0003093 regulation of glomerular filtration Added DEFINITION Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
2010-12-17 GO:0006939 smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
2010-12-17 GO:0007060 male meiosis chromosome segregation Added DEFINITION The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.
2010-12-17 GO:0007079 mitotic chromosome movement towards spindle pole Added DEFINITION The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
2010-12-17 GO:0007091 metaphase/anaphase transition of mitotic cell cycle Added DEFINITION The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins.
2010-12-17 GO:0007460 R8 cell fate commitment Added DEFINITION The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium.
2010-12-17 GO:0007513 pericardial cell differentiation Added DEFINITION The process in which a relatively unspecialized mesodermal cell acquires the specialized features of a pericardial cell. In insects, pericardial cells are loosely arranged non-myogenic cells that flank the cardioblasts and probably act in the filtration of hemolymph.
2010-12-17 GO:0009559 embryo sac central cell differentiation Added DEFINITION The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell.
2010-12-17 GO:0009994 oocyte differentiation Added DEFINITION The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
2010-12-17 GO:0010002 cardioblast differentiation Added DEFINITION The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
2010-12-17 GO:0010773 meiotic DNA recombinase assembly involved in meiotic gene conversion Added DEFINITION The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
2010-12-17 GO:0010789 meiotic sister chromatid cohesion involved in meiosis I Added DEFINITION The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.
2010-12-17 GO:0010832 negative regulation of myotube differentiation Added DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Added DEFINITION Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0014008 positive regulation of microglia differentiation Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
2010-12-17 GO:0014016 neuroblast differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
2010-12-17 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Added DEFINITION The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0014818 skeletal muscle satellite cell fate determination Added DEFINITION The process in which a cell becomes capable of differentiating autonomously into a satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.
2010-12-17 GO:0014845 stomach body smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.
2010-12-17 GO:0014847 proximal stomach smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.
2010-12-17 GO:0014848 urinary tract smooth muscle contraction Added DEFINITION A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.
2010-12-17 GO:0014902 myotube differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0021515 cell differentiation in spinal cord Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0021529 spinal cord oligodendrocyte cell differentiation Added DEFINITION The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0021709 cerebellar basket cell differentiation Added DEFINITION The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0021896 forebrain astrocyte differentiation Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
2010-12-17 GO:0090075 relaxation of muscle Added DEFINITION A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.
2010-12-17 GO:0030316 osteoclast differentiation Deleted DEFINITION The process whereby a relatively unspecialized monocyte acquires the specialized features of a osteoclast cell.
2010-12-17 GO:0070197 attachment of telomere to nuclear envelope Deleted DEFINITION The cell cycle process whereby physical connections are formed between telomeres and the nuclear envelope, facilitating bouquet formation.
2010-12-17 GO:0060531 neuroendocrine cell differentiation involved in prostate gland acinus development Deleted DEFINITION The process whereby relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.
2010-12-17 GO:0002329 pre-B cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
2010-12-17 GO:0021515 cell differentiation in spinal cord Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0023015 signal transduction by cis-phosphorylation Deleted DEFINITION The process whereby a signal is conveyed via the transfer of one or more phosphate groups by a kinase to a residue in the same kinase molecule.
2010-12-17 GO:0075239 zoospore formation Deleted DEFINITION The process by which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
2010-12-17 GO:0061102 stomach neuroendocrine cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.
2010-12-17 GO:0075043 maintenance of turgor in appressorium by melanization Deleted DEFINITION The process whereby melanin is produced in the appressorium of the symbiont on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0085032 modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade Deleted DEFINITION Any process by which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0010842 retina layer formation Deleted DEFINITION The process whereby the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
2010-12-17 GO:0045065 cytotoxic T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.
2010-12-17 GO:0048931 posterior lateral line nerve glial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.
2010-12-17 GO:0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Deleted DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.
2010-12-17 GO:0071825 protein-lipid complex subunit organization Deleted DEFINITION Any process by which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.
2010-12-17 GO:0048886 neuromast hair cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2010-12-17 GO:0071922 regulation of cohesin localization to chromatin Deleted DEFINITION Any process that modulates the frequency, rate or extent of a process by which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
2010-12-17 GO:0072147 glomerular parietal epithelial cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
2010-12-17 GO:0002296 T-helper 1 cell lineage commitment Deleted DEFINITION The process whereby a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.
2010-12-17 GO:0075333 positive regulation by host of symbiont adenylate cyclase-mediated signal transduction Deleted DEFINITION Any process by which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0003092 renal water retention Deleted DEFINITION The process whereby renal water excretion is decreased.
2010-12-17 GO:0043374 CD8-positive, alpha-beta T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
2010-12-17 GO:0075292 negative regulation of aplanospore formation Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process by which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
2010-12-17 GO:0071577 zinc II ion transmembrane transport Deleted DEFINITION A process whereby a zinc ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0000706 meiotic DNA double-strand break processing Deleted DEFINITION The cell cycle process whereby the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.
2010-12-17 GO:0075074 spore autophagy involved in appressorium formation on or near host Deleted DEFINITION The process by which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0061318 renal filtration cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0070574 cadmium ion transmembrane transport Deleted DEFINITION A process whereby a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0072134 nephrogenic mesenchyme morphogenesis Deleted DEFINITION The process by which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
2010-12-17 GO:0021994 progression of neural tube closure Deleted DEFINITION The process whereby the neural folds are fused extending from the initial closure points.
2010-12-17 GO:0021527 spinal cord association neuron differentiation Deleted DEFINITION The process whereby neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0002100 tRNA wobble adenosine to inosine editing Added DEFINITION The process in which an adenosine in position 34 of a tRNA is post-transcriptionally corverted to inosine.
2010-12-17 GO:0002292 T cell differentiation involved in immune response Added DEFINITION The process in which an antigenically nave T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2010-12-17 GO:0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Added DEFINITION The process in which an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.
2010-12-17 GO:0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation Added DEFINITION The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
2010-12-17 GO:0002313 mature B cell differentiation involved in immune response Added DEFINITION The process in which a nave B cell acquires the specialized features of a mature or memory B cell during an immune response.
2010-12-17 GO:0072295 specification of metanephric distal tubule identity Added DEFINITION The process in which the distal tubule of the metanephric nephron acquires its identity.
2010-12-17 GO:0072296 specification of metanephric loop of Henle identity Added DEFINITION The process in which the loop of Henle of the metanephric nephron acquires its identity.
2010-12-17 GO:0075262 negative regulation of spore-bearing organ development Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
2010-12-17 GO:0075270 negative regulation of aecium development Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0075287 positive regulation of sporangiospore formation Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
2010-12-17 GO:0085022 modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system Added DEFINITION The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0085025 modification by symbiont of host morphology or physiology via protein secreted by Tat complex Added DEFINITION The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072158 proximal tubule morphogenesis Added DEFINITION The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
2010-12-17 GO:0072160 nephron tubule epithelial cell differentiation Added DEFINITION The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.
2010-12-17 GO:0070306 lens fiber cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
2010-12-17 GO:0085025 modification by symbiont of host morphology or physiology via protein secreted by Tat complex Deleted DEFINITION The process by which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090200 positive regulation of release of cytochrome c from mitochondria Deleted DEFINITION Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process by which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
2010-12-17 GO:0006887 exocytosis Deleted DEFINITION A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.
2010-12-17 GO:0090376 seed trichome differentiation Deleted DEFINITION The process whereby a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.
2010-12-17 GO:0075161 negative regulation of G-protein alpha subunit-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0035378 carbon dioxide transmembrane transport Deleted DEFINITION A process whereby carbon dioxide (CO2) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0048761 collenchyma cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.
2010-12-17 GO:0072273 metanephric nephron morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.
2010-12-17 GO:0034219 carbohydrate transmembrane transport Deleted DEFINITION The process whereby a carbohydrate is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0030859 polarized epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.
2010-12-17 GO:0045595 regulation of cell differentiation Deleted DEFINITION Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features.
2010-12-17 GO:0055085 transmembrane transport Deleted DEFINITION The process whereby a solute is transported from one side of a membrane to the other.
2010-12-17 GO:0090122 cholesterol ester hydrolysis involved in cholesterol transport Deleted DEFINITION The cholesterol metabolic process by which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.
2010-12-17 GO:0071918 urea transmembrane transport Deleted DEFINITION The process whereby urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0045143 homologous chromosome segregation Deleted DEFINITION The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
2010-12-17 GO:0060842 arterial endothelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.
2010-12-17 GO:0072325 vulval cell fate commitment Deleted DEFINITION The process by which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
2010-12-17 GO:0003348 cardiac endothelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
2010-12-17 GO:0061208 cell differentiation involved in mesonephros development Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.
2010-12-17 GO:0072311 glomerular epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
2010-12-17 GO:0061104 adrenal chromaffin cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.
2010-12-17 GO:0075173 negative regulation of MAP kinase-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090335 regulation of brown fat cell differentiation Deleted DEFINITION Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
2010-12-17 GO:0051317 attachment of spindle microtubules to meiotic chromosome Deleted DEFINITION The cell cycle process whereby spindle microtubules become physically associated with a chromosome during meiosis.
2010-12-17 GO:0003311 pancreatic D cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.
2010-12-17 GO:0075181 positive regulation of symbiont transcription in response to host Deleted DEFINITION Any process by which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075082 positive regulation by host of symbiont transmembrane receptor-mediated signal transduction Deleted DEFINITION Any process by which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0051146 striated muscle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
2010-12-17 GO:0001752 compound eye photoreceptor fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
2010-12-17 GO:0042492 gamma-delta T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.
2010-12-17 GO:0075126 negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit Deleted DEFINITION Any process by which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0035558 phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling Deleted DEFINITION The process whereby a signal is passed from the insulin receptor to components of the phosphoinositide 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2010-12-17 GO:0002306 CD4-positive gamma-delta intraepithelial T cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2010-12-17 GO:0071851 mitotic G1 cell cycle arrest in response to nitrogen starvation Deleted DEFINITION The process by which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.
2010-12-17 GO:0002326 B cell lineage commitment Deleted DEFINITION The process whereby a lymphoid progenitor cell becomes committed to become any type of B cell.
2010-12-17 GO:0032837 distributive segregation Deleted DEFINITION The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a "backup" mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally.
2010-12-17 GO:0072240 metanephric DCT cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0075269 positive regulation of aecium development Deleted DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process by which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0090173 regulation of synaptonemal complex assembly Deleted DEFINITION Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process whereby the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.
2010-12-17 GO:0075131 positive regulation by symbiont of host protein kinase-mediated signal transduction Deleted DEFINITION Any process by which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0043367 CD4-positive, alpha-beta T cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.
2010-12-17 GO:0075304 negative regulation of basidiospore formation Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process by which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.
2010-12-17 GO:0010668 ectodermal cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0002317 plasma cell differentiation Deleted DEFINITION The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.
2010-12-17 GO:0023021 termination of signal transduction Deleted DEFINITION The signaling process whereby signal transduction is brought to an end rather than being reversibly modulated.
2010-12-17 GO:0042093 T-helper cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
2010-12-17 GO:0022010 central nervous system myelination Deleted DEFINITION The process whereby neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-17 GO:0075089 negative regulation by host of symbiont G-protein coupled receptor protein signal transduction Deleted DEFINITION Any process by which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075096 modulation by host of symbiont signal transduction mediated by G-protein gamma subunit Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0023070 signal transmission via air Deleted DEFINITION The process whereby a signal is conveyed via the air.
2010-12-17 GO:0006939 smooth muscle contraction Deleted DEFINITION A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
2010-12-17 GO:0071830 triglyceride-rich lipoprotein particle clearance Deleted DEFINITION The process by which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
2010-12-17 GO:0072284 metanephric S-shaped body morphogenesis Deleted DEFINITION The process by which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.
2010-12-17 GO:0048533 sporocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.
2010-12-17 GO:0045444 fat cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
2010-12-17 GO:0002303 gamma-delta T cell differentiation involved in immune response Deleted DEFINITION The process whereby an antigenically nave gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2010-12-17 GO:0023017 signal transmission via diffusible molecule Deleted DEFINITION The process whereby a signal is conveyed via a diffusible molecule.
2010-12-17 GO:0007520 myoblast fusion Deleted DEFINITION A process whereby non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2010-12-17 GO:0021520 spinal cord motor neuron cell fate specification Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
2010-12-17 GO:0014007 negative regulation of microglia differentiation Deleted DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell.
2010-12-17 GO:0075133 modulation by symbiont of host calcium or calmodulin-mediated signal transduction Deleted DEFINITION Any process by which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072077 renal vesicle morphogenesis Deleted DEFINITION The process by which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
2010-12-17 GO:0072327 vulval cell fate specification Deleted DEFINITION The process by which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
2010-12-17 GO:0023054 signal initiation by stretch effect Deleted DEFINITION The process whereby a stretch signal causes activation of a receptor.
2010-12-17 GO:0042707 ocellus photoreceptor cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
2010-12-17 GO:0010755 regulation of plasminogen activation Deleted DEFINITION Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process whereby plasminogen is processed to plasmin.
2010-12-17 GO:0001742 oenocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.
2010-12-17 GO:0050935 iridophore differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.
2010-12-17 GO:0031443 fast-twitch skeletal muscle fiber contraction Deleted DEFINITION A process whereby force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.
2010-12-17 GO:0072197 ureter morphogenesis Deleted DEFINITION The process by which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.
2010-12-17 GO:0035625 epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway Deleted DEFINITION The process whereby an epidermal growth factor receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGFR and GPCR signaling pathways.
2010-12-17 GO:0003361 noradrenergic neuron differentiation involved in brainstem development Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.
2010-12-17 GO:0060014 granulosa cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.
2010-12-17 GO:0075058 modulation of symbiont penetration peg initiation Deleted DEFINITION Any process that modulates the frequency, rate or extent of penetration peg initiation, the process whereby a relatively unspecialized cell start to acquire the characteristics of a mature penetration peg when the symbiont penetrates its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090132 epithelium migration Deleted DEFINITION The process by which the population of cells that make up an epithelium undergo directed movement.
2010-12-17 GO:0048865 stem cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a stem cell.
2010-12-17 GO:0060946 cardiac blood vessel endothelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.
2010-12-17 GO:0075016 appressorium formation on or near host Deleted DEFINITION The process by which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075241 positive regulation of zoospore formation Deleted DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process by which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
2010-12-17 GO:0075156 regulation of G-protein coupled receptor protein signaling pathway in response to host Deleted DEFINITION Any process by which the symbiont organism modulates the frequency, rate or extent of its G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0051891 positive regulation of cardioblast differentiation Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
2010-12-17 GO:0048863 stem cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
2010-12-17 GO:0060034 notochord cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
2010-12-17 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
2010-12-17 GO:0060486 Clara cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a Clara cell. A Clara cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.
2010-12-17 GO:0060891 limb granular cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.
2010-12-17 GO:0010745 negative regulation of macrophage derived foam cell differentiation Deleted DEFINITION Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process whereby a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
2010-12-17 GO:0010055 atrichoblast differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.
2010-12-17 GO:0002067 glandular epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
2010-12-17 GO:0023052 signaling Deleted DEFINITION The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered.
2010-12-17 GO:0090260 negative regulation of retinal ganglion cell axon guidance Deleted DEFINITION Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process by which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
2010-12-17 GO:0042706 eye photoreceptor cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
2010-12-17 GO:0021528 commissural neuron differentiation in spinal cord Deleted DEFINITION The process whereby neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0014839 myoblast migration involved in skeletal muscle regeneration Deleted DEFINITION The process whereby a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2010-12-17 GO:0075210 negative regulation by symbiont of host cAMP-mediated signal transduction Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0002136 wobble base lysidine biosynthesis Deleted DEFINITION The process whereby the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.
2010-12-17 GO:0075157 positive regulation of G-protein coupled receptor protein signaling pathway in response to host Deleted DEFINITION Any process by which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0014847 proximal stomach smooth muscle contraction Deleted DEFINITION A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.
2010-12-17 GO:0061319 nephrocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is a renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0021711 cerebellar unipolar brush cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0051756 meiotic sister chromatid centromere separation Deleted DEFINITION The cell cycle process whereby the centromeres of sister chromatids are physically detached from each other during meiosis.
2010-12-17 GO:0050934 late stripe melanocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).
2010-12-17 GO:0002574 thrombocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.
2010-12-17 GO:0023060 signal transmission Deleted DEFINITION The process whereby a signal is released and/or conveyed from one location to another.
2010-12-17 GO:0001949 sebaceous gland cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.
2010-12-17 GO:0007129 synapsis Deleted DEFINITION The cell cycle process whereby the side by side pairing and physical juxtaposition of homologous chromosomes is created at the metaphase plate.
2010-12-17 GO:0080170 hydrogen peroxide transmembrane transport Deleted DEFINITION The process whereby hydrogen peroxide is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.
2010-12-17 GO:0035555 initiation of Roundabout signal transduction Deleted DEFINITION The process whereby a SLIT protein causes activation of the receptor, Roundabout (ROBO).
2010-12-17 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Deleted DEFINITION Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process whereby the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0014813 skeletal muscle satellite cell commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.
2010-12-17 GO:0033260 nuclear DNA replication Deleted DEFINITION The process whereby new strands of genomic DNA are synthesized, using parental DNA as a template for DNA-dependent DNA polymerases, contributing to progression through S phase of the cell cycle.
2010-12-17 GO:0023022 termination of T cell signal transduction Deleted DEFINITION The signaling process whereby T cell signal transduction is brought to an end rather than being reversibly modulated.
2010-12-17 GO:0060942 neural crest-derived cardiac fibroblast cell differentiation Deleted DEFINITION The process whereby a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
2010-12-17 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Deleted DEFINITION The process whereby the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
2010-12-17 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response Deleted DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2010-12-17 GO:0007165 signal transduction Deleted DEFINITION The process whereby a signal is converted into a form where it can ultimately trigger a change in the state or activity of a cell. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
2010-12-17 GO:0002318 myeloid progenitor cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
2010-12-17 GO:0072186 metanephric cap morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
2010-12-17 GO:0071896 protein localization to adherens junction Deleted DEFINITION Any process by which a protein is transported to, and/or maintained at the adherens junction.
2010-12-17 GO:0015030 Cajal body Deleted DEFINITION A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
2010-12-17 GO:0031149 sorocarp stalk cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.
2010-12-17 GO:0051078 meiotic nuclear envelope disassembly Deleted DEFINITION The cell cycle process whereby the controlled breakdown of the nuclear envelope during meiotic cell division occurs.
2010-12-17 GO:0075080 negative regulation by host of symbiont receptor-mediated signal transduction Deleted DEFINITION Any process by which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0048888 neuromast mantle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2010-12-17 GO:0075059 positive regulation of symbiont penetration peg initiation Deleted DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg initiation, the process whereby a relatively unspecialized cell starts to acquire the characteristics of a mature penetration peg during the symbiont penetrating into its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075183 infection cushion formation on or near host Deleted DEFINITION The process by which an organized mass of hyphae is formed on or near the host organism, and numerous infective hyphae develop from the hyphae mass. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0090259 regulation of retinal ganglion cell axon guidance Deleted DEFINITION Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process by which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
2010-12-17 GO:0050933 early stripe melanocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).
2010-12-17 GO:0031980 mitochondrial lumen Deleted DEFINITION The volume enclosed by the mitochondrial inner membrane.
2010-12-17 GO:0072071 kidney interstitial fibroblast differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the kidney as it progresses from its formation to the mature state.
2010-12-17 GO:0072188 metanephric cap specification Deleted DEFINITION The process by which the metanephric cap acquires its identity.
2010-12-17 GO:0007130 synaptonemal complex assembly Deleted DEFINITION The cell cycle process whereby the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
2010-12-17 GO:0023009 initiation of T cell receptor signaling Deleted DEFINITION The process whereby a signal causes activation of T cell receptor signaling.
2010-12-17 GO:0072283 metanephric renal vesicle morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.
2010-12-17 GO:0072139 glomerular parietal epithelial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
2010-12-17 GO:0002099 tRNA wobble guanine modification Deleted DEFINITION The process whereby a guanine in t position 34 of a tRNA is post-transcriptionally modified.
2010-12-17 GO:0075093 modulation by host of symbiont signal transduction mediated by G-protein beta subunit Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072028 nephron morphogenesis Deleted DEFINITION The process by which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.
2010-12-17 GO:0060679 trifid subdivision of terminal units involved in ureteric bud branching Deleted DEFINITION The process whereby a ureteric bud splits into three units at its end.
2010-12-17 GO:0035559 MAPKKK cascade involved in epidermal growth factor receptor signaling Deleted DEFINITION The process whereby a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2010-12-17 GO:0060629 regulation of homologous chromosome segregation Deleted DEFINITION Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
2010-12-17 GO:0021702 cerebellar Purkinje cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
2010-12-17 GO:0030154 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0030221 basophil differentiation Deleted DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.
2010-12-17 GO:0030216 keratinocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a keratinocyte.
2010-12-17 GO:0001923 B-1 B cell differentiation Deleted DEFINITION The process whereby a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
2010-12-17 GO:0022011 myelination in peripheral nervous system Deleted DEFINITION The process whereby neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
2010-12-17 GO:0042490 mechanoreceptor differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.
2010-12-17 GO:0002328 pro-B cell differentiation Deleted DEFINITION The process whereby a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
2010-12-17 GO:0070588 calcium ion transmembrane transport Deleted DEFINITION A process whereby a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0075207 negative regulation by host of symbiont cAMP-mediated signal transduction Deleted DEFINITION Any process by which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0060431 primary lung bud formation Deleted DEFINITION The morphogenetic process whereby the foregut region specified to become the lung forms the initial left and right buds.
2010-12-17 GO:0030989 dynein-driven meiotic oscillatory nuclear movement Deleted DEFINITION The cell cycle process whereby oscillatory movement of the nucleus during meiotic prophase I occurs. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein. It is known to play a central role in meiotic recombination and homologous chromosome pairing; as observed in S. pombe.
2010-12-17 GO:0014830 arteriole smooth muscle contraction Deleted DEFINITION A process whereby force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.
2010-12-17 GO:0048052 R1/R6 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.
2010-12-17 GO:0090252 epithelium migration involved in imaginal disc-derived wing morphogenesis Deleted DEFINITION The process by which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.
2010-12-17 GO:0072258 metanephric interstitial fibroblast differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the metanephros as it progresses from its formation to the mature state.
2010-12-17 GO:0060610 mesenchymal cell differentiation involved in mammary gland development Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.
2010-12-17 GO:0060707 trophoblast giant cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.
2010-12-17 GO:0010789 meiotic sister chromatid cohesion involved in meiosis I Deleted DEFINITION The cell cycle process whereby sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.
2010-12-17 GO:0010520 regulation of reciprocal meiotic recombination Deleted DEFINITION Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate.
2010-12-17 GO:0048333 mesodermal cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
2010-12-17 GO:0007131 reciprocal meiotic recombination Deleted DEFINITION The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
2010-12-17 GO:0035624 receptor transactivation Deleted DEFINITION The process whereby a receptor is activated via signaling events from a receptor for a different ligand. Receptor transactivation is an example of cross-talk between signaling pathways and can occur through several different mechanisms.
2010-12-17 GO:0045446 endothelial cell differentiation Deleted DEFINITION The process whereby a mesodermal angioblast acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
2010-12-17 GO:0023006 signal initiation by amino acid Deleted DEFINITION The process whereby an amino acid signal causes activation of a receptor.
2010-12-17 GO:0075335 positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0032121 attachment of telomeric heterochromatin to spindle pole body Deleted DEFINITION The cell cycle process whereby physical connections are formed between telomeres and the spindle pole body, facilitating bouquet formation.
2010-12-17 GO:0048908 anterior lateral line ganglion neuron differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.
2010-12-17 GO:0002284 myeloid dendritic cell differentiation involved in immune response Deleted DEFINITION The process whereby an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.
2010-12-17 GO:0060709 glycogen cell differentiation involved in embryonic placenta development Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.
2010-12-17 GO:0072131 kidney mesenchyme morphogenesis Deleted DEFINITION The process by which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.
2010-12-17 GO:0021526 medial motor column neuron differentiation Deleted DEFINITION The process whereby differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0075176 negative regulation of cAMP-mediated signaling in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072173 metanephric tubule morphogenesis Deleted DEFINITION The process by which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.
2010-12-17 GO:0072282 metanephric nephron tubule morphogenesis Deleted DEFINITION The process by which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.
2010-12-17 GO:0072082 specification of proximal tubule identity Deleted DEFINITION The process by which the proximal tubule of the kidney nephron acquires its identity.
2010-12-17 GO:0006311 meiotic gene conversion Deleted DEFINITION The cell cycle process whereby genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele.
2010-12-17 GO:0010832 negative regulation of myotube differentiation Deleted DEFINITION Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0002338 B-1b B cell differentiation Deleted DEFINITION The process whereby B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
2010-12-17 GO:0010773 meiotic DNA recombinase assembly involved in meiotic gene conversion Deleted DEFINITION The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process whereby genetic information is transferred from one helix to another.
2010-12-17 GO:0060375 regulation of mast cell differentiation Deleted DEFINITION Any process that modulates the rate, frequency or extent of mast cell differentiation, the process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
2010-12-17 GO:0090033 positive regulation of filamentous growth Deleted DEFINITION Any process that increases the frequency, rate or extent of the process by which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2010-12-17 GO:0048928 posterior lateral line ganglion neuron differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.
2010-12-17 GO:0061322 disseminated nephrocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is a renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-12-17 GO:0007079 mitotic chromosome movement towards spindle pole Deleted DEFINITION The cell cycle process whereby the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
2010-12-17 GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development Deleted DEFINITION The process whereby a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.
2010-12-17 GO:0060920 cardiac pacemaker cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
2010-12-17 GO:0072086 specification of loop of Henle identity Deleted DEFINITION The process by which the loop of Henle of the kidney nephron acquires its identity.
2010-12-17 GO:0048235 pollen sperm cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.
2010-12-17 GO:0023068 signal transmission via phloem Deleted DEFINITION The process whereby a signal is conveyed via the phloem.
2010-12-17 GO:0090103 cochlea morphogenesis Deleted DEFINITION The process by which the cochlea is generated and organized.
2010-12-17 GO:0002316 follicular B cell differentiation Deleted DEFINITION The process whereby a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
2010-12-17 GO:0007464 R3/R4 cell fate commitment Deleted DEFINITION The process whereby the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.
2010-12-17 GO:0009563 synergid differentiation Deleted DEFINITION The process whereby an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell.
2010-12-17 GO:0090076 relaxation of skeletal muscle Deleted DEFINITION A process whereby the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.
2010-12-17 GO:0075103 modulation by host of symbiont calcium or calmodulin-mediated signal transduction Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0035051 cardiocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
2010-12-17 GO:0023019 signal transduction involved in regulation of gene expression Deleted DEFINITION Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process whereby a signal is released and/or conveyed from one location to another.
2010-12-17 GO:0075152 negative regulation of receptor-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0072052 juxtaglomerulus cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.
2010-12-17 GO:0009920 cell plate formation involved in plant-type cell wall biogenesis Deleted DEFINITION The cell cycle process whereby the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.
2010-12-17 GO:0002297 T-helper 2 cell lineage commitment Deleted DEFINITION The process whereby a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.
2010-12-17 GO:0030224 monocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
2010-12-17 GO:0001829 trophectodermal cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.
2010-12-17 GO:0075174 regulation of cAMP-mediated signaling in response to host Deleted DEFINITION Any process by which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0075268 regulation of aecium development Deleted DEFINITION Any process that modulates the frequency, rate or extent of aecium development, a process by which a cuplike structure containing chains of aeciospores is formed.
2010-12-17 GO:0090199 regulation of release of cytochrome c from mitochondria Deleted DEFINITION Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process by which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
2010-12-17 GO:0048772 leucophore differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.
2010-12-17 GO:0003362 noradrenergic neuron fate commitment involved in brainstem development Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem.
2010-12-17 GO:0075290 regulation of aplanospore formation Deleted DEFINITION Any process that modulates the frequency, rate or extent of aplanospore formation, a process by which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
2010-12-17 GO:0035168 larval lymph gland hemocyte differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.
2010-12-17 GO:0048759 xylem vessel member cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.
2010-12-17 GO:0023020 regulation of gene expression as a consequence of T cell signal transmission Deleted DEFINITION Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process whereby a T cell signal is released and/or conveyed from one location to another.
2010-12-17 GO:0061266 mesonephric interstitial fibroblast differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the mesonephros as it progresses from its formation to the mature state.
2010-12-17 GO:0051295 establishment of meiotic spindle localization Deleted DEFINITION The cell cycle process whereby the directed movement of the meiotic spindle to a specific location in the cell occurs.
2010-12-17 GO:0048056 R3/R4 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.
2010-12-17 GO:0007098 centrosome cycle Deleted DEFINITION The cell cycle process whereby centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
2010-12-17 GO:0002272 plasmacytoid dendritic cell differentiation involved in immune response Deleted DEFINITION The process whereby an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response.
2010-12-17 GO:0021997 neural plate axis specification Deleted DEFINITION The pattern specification process whereby the axes of the nervous system are established.
2010-12-17 GO:0072275 metanephric glomerulus morphogenesis Deleted DEFINITION The process by which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
2010-12-17 GO:0072196 proximal/distal pattern formation involved in pronephric nephron development Deleted DEFINITION The regionalization process by which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.
2010-12-17 GO:0055011 atrial cardiac muscle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.
2010-12-17 GO:0035349 coenzyme A transmembrane transport Deleted DEFINITION The process whereby coenzyme A is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
2010-12-17 GO:0007343 egg activation Deleted DEFINITION The process whereby the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.
2010-12-17 GO:0010830 regulation of myotube differentiation Deleted DEFINITION Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0003011 involuntary skeletal muscle contraction Deleted DEFINITION A process whereby force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.
2010-12-17 GO:0010002 cardioblast differentiation Deleted DEFINITION The process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
2010-12-17 GO:0031134 sister chromatid biorientation Deleted DEFINITION The cell cycle process whereby sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
2010-12-17 GO:0010775 meiotic strand invasion involved in meiotic gene conversion Deleted DEFINITION The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.
2010-12-17 GO:0021709 cerebellar basket cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0061259 mesonephric glomerular mesangial cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.
2010-12-17 GO:0021707 cerebellar granule cell differentiation Deleted DEFINITION The process whereby neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.
2010-12-17 GO:0071421 manganese ion transmembrane transport Deleted DEFINITION A process whereby a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2010-12-17 GO:0021514 ventral spinal cord interneuron differentiation Deleted DEFINITION The process whereby neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-12-17 GO:0072315 metanephric glomerular epithelial cell fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
2010-12-17 GO:0075191 autophagy of host cells on or near symbiont surface Deleted DEFINITION The process by which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0061268 mesonephric interstitial fibroblast fate commitment Deleted DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial cell.
2010-12-17 GO:0060580 ventral spinal cord interneuron fate determination Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.
2010-12-17 GO:0014902 myotube differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2010-12-17 GO:0001826 inner cell mass cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an inner cell mass cell.
2010-12-17 GO:0060490 lateral sprouting involved in lung morphogenesis Deleted DEFINITION The process whereby a branch forms along the side of the lung epithelial tube.
2010-12-17 GO:0000708 meiotic strand invasion Deleted DEFINITION The cell cycle process whereby the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.
2010-12-17 GO:0023045 signal transduction by conformational transition Deleted DEFINITION The process whereby a signal is conveyed via a conformational transition.
2010-12-17 GO:0003167 atrioventricular bundle cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.
2010-12-17 GO:0045128 negative regulation of reciprocal meiotic recombination Deleted DEFINITION Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate.
2010-12-17 GO:0075166 positive regulation of G-protein gamma subunit-mediated signal transduction in response to host Deleted DEFINITION Any process by which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0045064 T-helper 2 cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized T cell acquires specialized features of a Th2 cell.
2010-12-17 GO:0031444 slow-twitch skeletal muscle fiber contraction Deleted DEFINITION A process whereby force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
2010-12-17 GO:0090297 positive regulation of mitochondrial DNA replication Deleted DEFINITION Any process that increases the rate, frequency or extent of the process whereby new strands of DNA are synthesized in the mitochondrion.
2010-12-17 GO:0060836 lymphatic endothelial cell differentiation Deleted DEFINITION The process whereby a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.
2010-12-17 GO:0075081 modulation by host of symbiont transmembrane receptor-mediated signal transduction Deleted DEFINITION Any process by which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2010-12-17 GO:0048913 anterior lateral line nerve glial cell differentiation Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.
2010-12-17 GO:0014818 skeletal muscle satellite cell fate determination Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.
2010-12-17 GO:0051231 spindle elongation Deleted DEFINITION The cell cycle process whereby the distance is lengthened between poles of the spindle.
2010-12-17 GO:0048866 stem cell fate specification Deleted DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
2010-12-17 GO:0055119 relaxation of cardiac muscle Deleted DEFINITION The process whereby the extent of cardiac muscle contraction is reduced.

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2010-12-17 GO:0072498 embryonic skeletal joint development Added RELATION is a GO:0048706 (embryonic skeletal system development)
2010-12-17 GO:0072499 photoreceptor cell axon guidance Added RELATION is a GO:0007411 (axon guidance)
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added RELATION part of GO:0060070 (canonical Wnt signaling pathway)
2010-12-17 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway Added RELATION is a GO:0031623 (receptor internalization)
2010-12-17 GO:0005759 mitochondrial matrix Added RELATION is a GO:0070013 (intracellular organelle lumen)
2010-12-17 GO:0005759 mitochondrial matrix Deleted RELATION part of GO:0031980 (mitochondrial lumen)
2010-12-17 GO:0031980 mitochondrial lumen Deleted RELATION is a GO:0070013 (intracellular organelle lumen)
2010-12-17 GO:0031980 mitochondrial lumen Deleted RELATION is a GO:0044429 (mitochondrial part)
2010-12-17 GO:0072037 mesenchymal stem cell differentiation involved in nephron morphogenesis Added RELATION is a GO:0072497 (mesenchymal stem cell differentiation)
2010-12-17 GO:0072037 mesenchymal stem cell differentiation involved in nephron morphogenesis Deleted RELATION is a GO:0048863 (stem cell differentiation)
2010-12-17 GO:0060272 embryonic skeletal joint morphogenesis Added RELATION part of GO:0072498 (embryonic skeletal joint development)
2010-12-17 GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation Added RELATION part of GO:0072497 (mesenchymal stem cell differentiation)
2010-12-17 GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation Deleted RELATION part of GO:0048863 (stem cell differentiation)
2010-12-17 GO:0072494 host multivesicular body Added RELATION is a GO:0044184 (host cell late endosome)
2010-12-17 GO:0072495 host cell Cajal body Added RELATION is a GO:0044094 (host cell nuclear part)
2010-12-17 GO:0072495 host cell Cajal body Added RELATION part of GO:0044095 (host cell nucleoplasm)
2010-12-17 GO:0072492 host cell mitochondrial intermembrane space Added RELATION is a GO:0033655 (host cell cytoplasm part)
2010-12-17 GO:0072492 host cell mitochondrial intermembrane space Added RELATION part of GO:0044190 (host cell mitochondrial envelope)
2010-12-17 GO:0072493 host cell endosome lumen Added RELATION part of GO:0044174 (host cell endosome)
2010-12-17 GO:0072493 host cell endosome lumen Added RELATION is a GO:0033655 (host cell cytoplasm part)
2010-12-17 GO:0090394 negative regulation of excitatory postsynaptic membrane potential Added RELATION is a GO:0060079 (regulation of excitatory postsynaptic membrane potential)
2010-12-17 GO:0090395 plant cell papilla Added RELATION is a GO:0042995 (cell projection)
2010-12-17 GO:0090396 leaf papilla Added RELATION is a GO:0090395 (plant cell papilla)
2010-12-17 GO:0090397 stigma papilla Added RELATION is a GO:0090395 (plant cell papilla)
2010-12-17 GO:0072496 Pup transferase activity Added RELATION is a GO:0019787 (ubiquitin-like protein transferase activity)
2010-12-17 GO:0072497 mesenchymal stem cell differentiation Added RELATION is a GO:0048863 (stem cell differentiation)

Cross-references

Timestamp GO ID GO Term Name Action Category Detail
2010-12-17 GO:0031980 mitochondrial lumen Deleted XREF NIF_Subcellular:sao-1899375636
2010-12-17 GO:0005759 mitochondrial matrix Added XREF NIF_Subcellular:sao-1899375636

Other

Timestamp GO ID GO Term Name Action Category Detail
2010-12-17 GO:0005759 mitochondrial matrix Added SECONDARY GO:0031980 (mitochondrial lumen)
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