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GO Term History: Displaying 154 audit records for all terms for the date 2010-10-07

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2010-10-07 GO:0035579 specific granule membrane Added DEFINITION The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
2010-10-07 GO:0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed Added DEFINITION A process that modulates flagellar motility by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein. This process is observed in prokaryotes, where it requires cyclic di-GMP binding to the brake protein.
2010-10-07 GO:0001616 growth hormone secretagogue receptor activity Added DEFINITION Combining with ghrelin to initiate a change in cell activity.
2010-10-07 GO:0034774 secretory granule lumen Added DEFINITION The volume enclosed by the membrane of a secretory granule.
2010-10-07 GO:0035577 azurophil granule membrane Added DEFINITION The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2010-10-07 GO:0001603 vasopressin-like receptor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2010-10-07 GO:0070438 mTOR-FKBP12-rapamycin complex Updated TERM mTOR-FKBP12-rapamycin complex
2010-10-07 GO:0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed Added TERM regulation of flagellar cell motility by regulation of motor speed
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added TERM retinoic acid receptor signaling pathway involved in pronephric field specification
2010-10-07 GO:0035577 azurophil granule membrane Added TERM azurophil granule membrane
2010-10-07 GO:0035578 azurophil granule lumen Added TERM azurophil granule lumen
2010-10-07 GO:0035579 specific granule membrane Added TERM specific granule membrane
2010-10-07 GO:0035580 specific granule lumen Added TERM specific granule lumen
2010-10-07 GO:0001624 RDC1 receptor activity Deleted TERM RDC1 receptor activity
2010-10-07 GO:0001625 Epstein-Barr Virus-induced receptor activity Deleted TERM Epstein-Barr Virus-induced receptor activity
2010-10-07 GO:0001628 gastropyloric receptor activity Updated TERM gastropyloric receptor activity
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted TERM non-G-protein coupled 7TM receptor activity
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted TERM inositol or phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0004537 caspase-activated deoxyribonuclease activity Deleted TERM caspase-activated deoxyribonuclease activity
2010-10-07 GO:0004718 Janus kinase activity Deleted TERM Janus kinase activity
2010-10-07 GO:0004770 sterol carrier protein X-related thiolase activity Deleted TERM sterol carrier protein X-related thiolase activity
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted TERM G-protein coupled serotonin receptor activity
2010-10-07 GO:0004804 P-element encoded transposase activity Deleted TERM P-element encoded transposase activity
2010-10-07 GO:0001621 ADP receptor activity Updated TERM ADP receptor activity
2010-10-07 GO:0001622 super conserved receptor expressed in brain receptor activity Deleted TERM super conserved receptor expressed in brain receptor activity
2010-10-07 GO:0001623 Mas proto-oncogene receptor activity Deleted TERM Mas proto-oncogene receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM Mas proto-oncogene receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM orphan G protein coupled receptor activity
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted SYNONYM inositol/phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0001622 super conserved receptor expressed in brain receptor activity Deleted SYNONYM SREB receptor
2010-10-07 GO:0001625 Epstein-Barr Virus-induced receptor activity Deleted SYNONYM EBV-induced receptor
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM G-protein coupled receptor activity, unknown ligand
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM orphan G-protein coupled receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM orphan GPCR activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM orphan G protein coupled receptor activity
2010-10-07 GO:0001637 G-protein coupled chemoattractant receptor activity Added SYNONYM G-protein coupled chemoattractant receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM orphan GPCR activity
2010-10-07 GO:0004993 serotonin receptor activity Added SYNONYM G-protein coupled serotonin receptor activity
2010-10-07 GO:0004993 serotonin receptor activity Added SYNONYM G-protein-coupled serotonin receptor activity
2010-10-07 GO:0035579 specific granule membrane Added SYNONYM secondary granule membrane
2010-10-07 GO:0004713 protein tyrosine kinase activity Added SYNONYM Janus kinase activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM EBV-induced receptor
2010-10-07 GO:0031386 protein tag Added SYNONYM covalent modifier
2010-10-07 GO:0048793 pronephros development Added SYNONYM pronephric kidney development
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SYNONYM non-G-protein-coupled 7TM receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM orphan G-protein coupled receptor activity
2010-10-07 GO:0004971 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Added SYNONYM AMPA receptor activity
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted SYNONYM G protein coupled serotonin receptor activity
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted SYNONYM G-protein-coupled serotonin receptor activity
2010-10-07 GO:0004718 Janus kinase activity Deleted SYNONYM JAK
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted SYNONYM non G protein coupled 7TM receptor activity
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted SYNONYM non-G-protein-coupled 7TM receptor activity
2010-10-07 GO:0035580 specific granule lumen Added SYNONYM secondary granule lumen
2010-10-07 GO:0004803 transposase activity Added SYNONYM P-element encoded transposase activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM RDC1 receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM super conserved receptor expressed in brain receptor activity
2010-10-07 GO:0035577 azurophil granule membrane Added SYNONYM primary granule membrane
2010-10-07 GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity Added SYNONYM sterol carrier protein X-related thiolase activity
2010-10-07 GO:0072120 pronephros maturation Added SYNONYM pronephric kidney maturation
2010-10-07 GO:0001621 ADP receptor activity Added SYNONYM platelet ADP receptor activity
2010-10-07 GO:0004713 protein tyrosine kinase activity Added SYNONYM JAK
2010-10-07 GO:0004993 serotonin receptor activity Added SYNONYM G protein coupled serotonin receptor activity
2010-10-07 GO:0034671 retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification Added SYNONYM retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification
2010-10-07 GO:0035578 azurophil granule lumen Added SYNONYM primary granule lumen
2010-10-07 GO:0072116 pronephros formation Added SYNONYM pronephric kidney formation
2010-10-07 GO:0001621 ADP receptor activity Added DEFINITION Combining with ADP to initiate a change in cell activity. ADP receptors are present at the surface of platelets, where they are involved in platelet aggregation.
2010-10-07 GO:0004986 delta-opioid receptor activity Added DEFINITION Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands.
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added DEFINITION The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop.
2010-10-07 GO:0035580 specific granule lumen Added DEFINITION The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
2010-10-07 GO:0001604 urotensin II receptor activity Added DEFINITION Combining with urotensin II to initiate a change in cell activity.
2010-10-07 GO:0001626 nociceptin receptor activity Added DEFINITION Combining with the peptide nociceptin/orphanin-FQ to initiate a change in cell activity.
2010-10-07 GO:0001648 proteinase activated receptor activity Added DEFINITION A G-protein coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor.
2010-10-07 GO:0004704 NF-kappaB-inducing kinase activity Added DEFINITION Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).
2010-10-07 GO:0004889 acetylcholine-activated cation-selective channel activity Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that acts as a nicotinic acetylcholine receptor, and opens upon binidng acetylcholine.
2010-10-07 GO:0035578 azurophil granule lumen Added DEFINITION The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2010-10-07 GO:0001635 calcitonin gene-related peptide receptor activity Added DEFINITION Combining with a calcitonin gene-related polypeptide to initiate a change in cell activity.
2010-10-07 GO:0070438 mTOR-FKBP12-rapamycin complex Added DEFINITION A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus).
2010-10-07 GO:0001594 trace-amine receptor activity Added DEFINITION Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.
2010-10-07 GO:0001596 angiotensin type I receptor activity Added DEFINITION An angionensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.
2010-10-07 GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity Added DEFINITION An ionotropic glutamate receptor activity that exhibits slow gating by glutamate, acts by opening a nonselective cation channel, and can be activated by L-aspartate.
2010-10-07 GO:0070438 mTOR-FKBP12-rapamycin complex Deleted DEFINITION A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase and the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A).
2010-10-07 GO:0034774 secretory granule lumen Deleted DEFINITION : The volume enclosed by the membrane of a secretory granule.
2010-10-07 GO:0001586 Gi/o-coupled serotonin receptor activity Added DEFINITION A serotonin receptor activity that acts via coupling to Gi/Go to initiate a change in cell activity.
2010-10-07 GO:0001587 Gq/11-coupled serotonin receptor activity Added DEFINITION A serotonin receptor activity that acts via coupling to G11/q to initiate a change in cell activity.
2010-10-07 GO:0001637 G-protein coupled chemoattractant receptor activity Added DEFINITION Combining with a chemoattractant peptide to initiate a G-protein mediated change in cell activity.
2010-10-07 GO:0004945 angiotensin type II receptor activity Added DEFINITION An angionensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms.
2010-10-07 GO:0004971 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Added DEFINITION An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.
2010-10-07 GO:0015277 kainate selective glutamate receptor activity Added DEFINITION An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.
2010-10-07 GO:0019414 aerobic respiration, using sulfur or sulfate as electron donor Added DEFINITION An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.
2010-10-07 GO:0001628 gastropyloric receptor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added SECONDARY GO:0004434 (inositol or phosphatidylinositol phosphodiesterase activity)
2010-10-07 GO:0004536 deoxyribonuclease activity Added SECONDARY GO:0004537 (caspase-activated deoxyribonuclease activity)
2010-10-07 GO:0004713 protein tyrosine kinase activity Added SECONDARY GO:0004718 (Janus kinase activity)
2010-10-07 GO:0004803 transposase activity Added SECONDARY GO:0004804 (P-element encoded transposase activity)
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SECONDARY GO:0004926 (non-G-protein coupled 7TM receptor activity)
2010-10-07 GO:0004927 sevenless receptor activity Added OBSOLETION consider GO:0004888 (transmembrane signaling receptor activity)
2010-10-07 GO:0004927 sevenless receptor activity Deleted OBSOLETION consider GO:0004926 (non-G-protein coupled 7TM receptor activity)
2010-10-07 GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity Added SECONDARY GO:0004770 (sterol carrier protein X-related thiolase activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001625 (Epstein-Barr Virus-induced receptor activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001624 (RDC1 receptor activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001623 (Mas proto-oncogene receptor activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001622 (super conserved receptor expressed in brain receptor activity)
2010-10-07 GO:0004993 serotonin receptor activity Added SECONDARY GO:0016609 (G-protein coupled serotonin receptor activity)
2010-10-07 GO:0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed Added RELATION is a GO:2000153 (regulation of flagellar cell motility)
2010-10-07 GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity Added RELATION is a GO:0003824 (catalytic activity)
2010-10-07 GO:0031089 platelet dense granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0031089 platelet dense granule lumen Deleted RELATION is a GO:0060205 (cytoplasmic membrane-bounded vesicle lumen)
2010-10-07 GO:0031093 platelet alpha granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0031093 platelet alpha granule lumen Deleted RELATION is a GO:0060205 (cytoplasmic membrane-bounded vesicle lumen)
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added RELATION is a GO:0048384 (retinoic acid receptor signaling pathway)
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added RELATION part of GO:0039003 (pronephric field specification)
2010-10-07 GO:0035577 azurophil granule membrane Added RELATION part of GO:0042582 (azurophil granule)
2010-10-07 GO:0035577 azurophil granule membrane Added RELATION is a GO:0030667 (secretory granule membrane)
2010-10-07 GO:0035578 azurophil granule lumen Added RELATION part of GO:0042582 (azurophil granule)
2010-10-07 GO:0035578 azurophil granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0035579 specific granule membrane Added RELATION part of GO:0042581 (specific granule)
2010-10-07 GO:0035579 specific granule membrane Added RELATION is a GO:0030667 (secretory granule membrane)
2010-10-07 GO:0035580 specific granule lumen Added RELATION part of GO:0042581 (specific granule)
2010-10-07 GO:0035580 specific granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0034466 chromaffin granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0034466 chromaffin granule lumen Deleted RELATION is a GO:0060205 (cytoplasmic membrane-bounded vesicle lumen)
2010-10-07 GO:0043160 acrosomal lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted RELATION is a GO:0004993 (serotonin receptor activity)
2010-10-07 GO:0004718 Janus kinase activity Deleted RELATION is a GO:0004716 (receptor signaling protein tyrosine kinase activity)
2010-10-07 GO:0004770 sterol carrier protein X-related thiolase activity Deleted RELATION is a GO:0003824 (catalytic activity)
2010-10-07 GO:0004537 caspase-activated deoxyribonuclease activity Deleted RELATION is a GO:0004536 (deoxyribonuclease activity)
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted RELATION is a GO:0008081 (phosphoric diester hydrolase activity)
2010-10-07 GO:0004435 phosphatidylinositol phospholipase C activity Added RELATION is a GO:0008081 (phosphoric diester hydrolase activity)
2010-10-07 GO:0004804 P-element encoded transposase activity Deleted RELATION is a GO:0004803 (transposase activity)
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted RELATION is a GO:0004888 (transmembrane signaling receptor activity)
2010-10-07 GO:0001623 Mas proto-oncogene receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001624 RDC1 receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001625 Epstein-Barr Virus-induced receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001628 gastropyloric receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001622 super conserved receptor expressed in brain receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0004435 phosphatidylinositol phospholipase C activity Deleted RELATION is a GO:0004434 (inositol or phosphatidylinositol phosphodiesterase activity)
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted XREF EC:3.1.4.-
2010-10-07 GO:0004713 protein tyrosine kinase activity Added XREF EC:2.7.11.-
2010-10-07 GO:0004718 Janus kinase activity Deleted XREF EC:2.7.11.-
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added XREF EC:3.1.4.-
2010-10-07 GO:0004986 delta-opioid receptor activity Added XREF Wikipedia:Delta_Opioid_receptor
2010-10-07 GO:0004988 mu-opioid receptor activity Added XREF Wikipedia:Mu_Opioid_receptor
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SYNONYM non-G-protein coupled 7TM receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM Epstein-Barr Virus-induced receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM SREB receptor
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added SYNONYM inositol/phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0001616 growth hormone secretagogue receptor activity Added SYNONYM ghrelin receptor activity
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added SYNONYM inositol or phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0039017 pattern specification involved in pronephros development Added SYNONYM pattern specification involved in pronephric kidney development
2010-10-07 GO:0004536 deoxyribonuclease activity Added SYNONYM caspase-activated deoxyribonuclease activity
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SYNONYM non G protein coupled 7TM receptor activity
2010-10-07 GO:0034672 anterior/posterior pattern specification involved in pronephros development Added SYNONYM anterior/posterior pattern specification involved in pronephric kidney development
2010-10-07 GO:0072118 pronephros structural organization Added SYNONYM pronephric kidney structural organization
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM G-protein coupled receptor activity, unknown ligand

Terms

Timestamp GO ID GO Term Name Action Category Detail
2010-10-07 GO:0070438 mTOR-FKBP12-rapamycin complex Updated TERM mTOR-FKBP12-rapamycin complex
2010-10-07 GO:0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed Added TERM regulation of flagellar cell motility by regulation of motor speed
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added TERM retinoic acid receptor signaling pathway involved in pronephric field specification
2010-10-07 GO:0035577 azurophil granule membrane Added TERM azurophil granule membrane
2010-10-07 GO:0035578 azurophil granule lumen Added TERM azurophil granule lumen
2010-10-07 GO:0035579 specific granule membrane Added TERM specific granule membrane
2010-10-07 GO:0035580 specific granule lumen Added TERM specific granule lumen
2010-10-07 GO:0001624 RDC1 receptor activity Deleted TERM RDC1 receptor activity
2010-10-07 GO:0001625 Epstein-Barr Virus-induced receptor activity Deleted TERM Epstein-Barr Virus-induced receptor activity
2010-10-07 GO:0001628 gastropyloric receptor activity Updated TERM gastropyloric receptor activity
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted TERM non-G-protein coupled 7TM receptor activity
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted TERM inositol or phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0004537 caspase-activated deoxyribonuclease activity Deleted TERM caspase-activated deoxyribonuclease activity
2010-10-07 GO:0004718 Janus kinase activity Deleted TERM Janus kinase activity
2010-10-07 GO:0004770 sterol carrier protein X-related thiolase activity Deleted TERM sterol carrier protein X-related thiolase activity
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted TERM G-protein coupled serotonin receptor activity
2010-10-07 GO:0004804 P-element encoded transposase activity Deleted TERM P-element encoded transposase activity
2010-10-07 GO:0001621 ADP receptor activity Updated TERM ADP receptor activity
2010-10-07 GO:0001622 super conserved receptor expressed in brain receptor activity Deleted TERM super conserved receptor expressed in brain receptor activity
2010-10-07 GO:0001623 Mas proto-oncogene receptor activity Deleted TERM Mas proto-oncogene receptor activity

Obsoletions

Timestamp GO ID GO Term Name Action Category Detail
2010-10-07 GO:0004927 sevenless receptor activity Added OBSOLETION consider GO:0004888 (transmembrane signaling receptor activity)
2010-10-07 GO:0004927 sevenless receptor activity Deleted OBSOLETION consider GO:0004926 (non-G-protein coupled 7TM receptor activity)

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2010-10-07 GO:0035579 specific granule membrane Added DEFINITION The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
2010-10-07 GO:0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed Added DEFINITION A process that modulates flagellar motility by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein. This process is observed in prokaryotes, where it requires cyclic di-GMP binding to the brake protein.
2010-10-07 GO:0001616 growth hormone secretagogue receptor activity Added DEFINITION Combining with ghrelin to initiate a change in cell activity.
2010-10-07 GO:0034774 secretory granule lumen Added DEFINITION The volume enclosed by the membrane of a secretory granule.
2010-10-07 GO:0035577 azurophil granule membrane Added DEFINITION The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2010-10-07 GO:0001603 vasopressin-like receptor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM Mas proto-oncogene receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM orphan G protein coupled receptor activity
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted SYNONYM inositol/phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0001622 super conserved receptor expressed in brain receptor activity Deleted SYNONYM SREB receptor
2010-10-07 GO:0001625 Epstein-Barr Virus-induced receptor activity Deleted SYNONYM EBV-induced receptor
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM G-protein coupled receptor activity, unknown ligand
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM orphan G-protein coupled receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM orphan GPCR activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Deleted SYNONYM orphan G protein coupled receptor activity
2010-10-07 GO:0001637 G-protein coupled chemoattractant receptor activity Added SYNONYM G-protein coupled chemoattractant receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM orphan GPCR activity
2010-10-07 GO:0004993 serotonin receptor activity Added SYNONYM G-protein coupled serotonin receptor activity
2010-10-07 GO:0004993 serotonin receptor activity Added SYNONYM G-protein-coupled serotonin receptor activity
2010-10-07 GO:0035579 specific granule membrane Added SYNONYM secondary granule membrane
2010-10-07 GO:0004713 protein tyrosine kinase activity Added SYNONYM Janus kinase activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM EBV-induced receptor
2010-10-07 GO:0031386 protein tag Added SYNONYM covalent modifier
2010-10-07 GO:0048793 pronephros development Added SYNONYM pronephric kidney development
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SYNONYM non-G-protein-coupled 7TM receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM orphan G-protein coupled receptor activity
2010-10-07 GO:0004971 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Added SYNONYM AMPA receptor activity
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted SYNONYM G protein coupled serotonin receptor activity
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted SYNONYM G-protein-coupled serotonin receptor activity
2010-10-07 GO:0004718 Janus kinase activity Deleted SYNONYM JAK
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted SYNONYM non G protein coupled 7TM receptor activity
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted SYNONYM non-G-protein-coupled 7TM receptor activity
2010-10-07 GO:0035580 specific granule lumen Added SYNONYM secondary granule lumen
2010-10-07 GO:0004803 transposase activity Added SYNONYM P-element encoded transposase activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM RDC1 receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM super conserved receptor expressed in brain receptor activity
2010-10-07 GO:0035577 azurophil granule membrane Added SYNONYM primary granule membrane
2010-10-07 GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity Added SYNONYM sterol carrier protein X-related thiolase activity
2010-10-07 GO:0072120 pronephros maturation Added SYNONYM pronephric kidney maturation
2010-10-07 GO:0001621 ADP receptor activity Added SYNONYM platelet ADP receptor activity
2010-10-07 GO:0004713 protein tyrosine kinase activity Added SYNONYM JAK
2010-10-07 GO:0004993 serotonin receptor activity Added SYNONYM G protein coupled serotonin receptor activity
2010-10-07 GO:0034671 retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification Added SYNONYM retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification
2010-10-07 GO:0035578 azurophil granule lumen Added SYNONYM primary granule lumen
2010-10-07 GO:0072116 pronephros formation Added SYNONYM pronephric kidney formation
2010-10-07 GO:0001621 ADP receptor activity Added DEFINITION Combining with ADP to initiate a change in cell activity. ADP receptors are present at the surface of platelets, where they are involved in platelet aggregation.
2010-10-07 GO:0004986 delta-opioid receptor activity Added DEFINITION Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands.
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added DEFINITION The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop.
2010-10-07 GO:0035580 specific granule lumen Added DEFINITION The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
2010-10-07 GO:0001604 urotensin II receptor activity Added DEFINITION Combining with urotensin II to initiate a change in cell activity.
2010-10-07 GO:0001626 nociceptin receptor activity Added DEFINITION Combining with the peptide nociceptin/orphanin-FQ to initiate a change in cell activity.
2010-10-07 GO:0001648 proteinase activated receptor activity Added DEFINITION A G-protein coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor.
2010-10-07 GO:0004704 NF-kappaB-inducing kinase activity Added DEFINITION Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).
2010-10-07 GO:0004889 acetylcholine-activated cation-selective channel activity Added DEFINITION Catalysis of the transmembrane transfer of a cation by a channel that acts as a nicotinic acetylcholine receptor, and opens upon binidng acetylcholine.
2010-10-07 GO:0035578 azurophil granule lumen Added DEFINITION The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2010-10-07 GO:0001635 calcitonin gene-related peptide receptor activity Added DEFINITION Combining with a calcitonin gene-related polypeptide to initiate a change in cell activity.
2010-10-07 GO:0070438 mTOR-FKBP12-rapamycin complex Added DEFINITION A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus).
2010-10-07 GO:0001594 trace-amine receptor activity Added DEFINITION Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.
2010-10-07 GO:0001596 angiotensin type I receptor activity Added DEFINITION An angionensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.
2010-10-07 GO:0004972 N-methyl-D-aspartate selective glutamate receptor activity Added DEFINITION An ionotropic glutamate receptor activity that exhibits slow gating by glutamate, acts by opening a nonselective cation channel, and can be activated by L-aspartate.
2010-10-07 GO:0070438 mTOR-FKBP12-rapamycin complex Deleted DEFINITION A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase and the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A).
2010-10-07 GO:0034774 secretory granule lumen Deleted DEFINITION : The volume enclosed by the membrane of a secretory granule.
2010-10-07 GO:0001586 Gi/o-coupled serotonin receptor activity Added DEFINITION A serotonin receptor activity that acts via coupling to Gi/Go to initiate a change in cell activity.
2010-10-07 GO:0001587 Gq/11-coupled serotonin receptor activity Added DEFINITION A serotonin receptor activity that acts via coupling to G11/q to initiate a change in cell activity.
2010-10-07 GO:0001637 G-protein coupled chemoattractant receptor activity Added DEFINITION Combining with a chemoattractant peptide to initiate a G-protein mediated change in cell activity.
2010-10-07 GO:0004945 angiotensin type II receptor activity Added DEFINITION An angionensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms.
2010-10-07 GO:0004971 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity Added DEFINITION An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.
2010-10-07 GO:0015277 kainate selective glutamate receptor activity Added DEFINITION An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.
2010-10-07 GO:0019414 aerobic respiration, using sulfur or sulfate as electron donor Added DEFINITION An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.
2010-10-07 GO:0001628 gastropyloric receptor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SYNONYM non-G-protein coupled 7TM receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM Epstein-Barr Virus-induced receptor activity
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM SREB receptor
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added SYNONYM inositol/phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0001616 growth hormone secretagogue receptor activity Added SYNONYM ghrelin receptor activity
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added SYNONYM inositol or phosphatidylinositol phosphodiesterase activity
2010-10-07 GO:0039017 pattern specification involved in pronephros development Added SYNONYM pattern specification involved in pronephric kidney development
2010-10-07 GO:0004536 deoxyribonuclease activity Added SYNONYM caspase-activated deoxyribonuclease activity
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SYNONYM non G protein coupled 7TM receptor activity
2010-10-07 GO:0034672 anterior/posterior pattern specification involved in pronephros development Added SYNONYM anterior/posterior pattern specification involved in pronephric kidney development
2010-10-07 GO:0072118 pronephros structural organization Added SYNONYM pronephric kidney structural organization
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SYNONYM G-protein coupled receptor activity, unknown ligand

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2010-10-07 GO:0071945 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed Added RELATION is a GO:2000153 (regulation of flagellar cell motility)
2010-10-07 GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity Added RELATION is a GO:0003824 (catalytic activity)
2010-10-07 GO:0031089 platelet dense granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0031089 platelet dense granule lumen Deleted RELATION is a GO:0060205 (cytoplasmic membrane-bounded vesicle lumen)
2010-10-07 GO:0031093 platelet alpha granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0031093 platelet alpha granule lumen Deleted RELATION is a GO:0060205 (cytoplasmic membrane-bounded vesicle lumen)
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added RELATION is a GO:0048384 (retinoic acid receptor signaling pathway)
2010-10-07 GO:0035576 retinoic acid receptor signaling pathway involved in pronephric field specification Added RELATION part of GO:0039003 (pronephric field specification)
2010-10-07 GO:0035577 azurophil granule membrane Added RELATION part of GO:0042582 (azurophil granule)
2010-10-07 GO:0035577 azurophil granule membrane Added RELATION is a GO:0030667 (secretory granule membrane)
2010-10-07 GO:0035578 azurophil granule lumen Added RELATION part of GO:0042582 (azurophil granule)
2010-10-07 GO:0035578 azurophil granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0035579 specific granule membrane Added RELATION part of GO:0042581 (specific granule)
2010-10-07 GO:0035579 specific granule membrane Added RELATION is a GO:0030667 (secretory granule membrane)
2010-10-07 GO:0035580 specific granule lumen Added RELATION part of GO:0042581 (specific granule)
2010-10-07 GO:0035580 specific granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0034466 chromaffin granule lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0034466 chromaffin granule lumen Deleted RELATION is a GO:0060205 (cytoplasmic membrane-bounded vesicle lumen)
2010-10-07 GO:0043160 acrosomal lumen Added RELATION is a GO:0034774 (secretory granule lumen)
2010-10-07 GO:0016609 G-protein coupled serotonin receptor activity Deleted RELATION is a GO:0004993 (serotonin receptor activity)
2010-10-07 GO:0004718 Janus kinase activity Deleted RELATION is a GO:0004716 (receptor signaling protein tyrosine kinase activity)
2010-10-07 GO:0004770 sterol carrier protein X-related thiolase activity Deleted RELATION is a GO:0003824 (catalytic activity)
2010-10-07 GO:0004537 caspase-activated deoxyribonuclease activity Deleted RELATION is a GO:0004536 (deoxyribonuclease activity)
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted RELATION is a GO:0008081 (phosphoric diester hydrolase activity)
2010-10-07 GO:0004435 phosphatidylinositol phospholipase C activity Added RELATION is a GO:0008081 (phosphoric diester hydrolase activity)
2010-10-07 GO:0004804 P-element encoded transposase activity Deleted RELATION is a GO:0004803 (transposase activity)
2010-10-07 GO:0004926 non-G-protein coupled 7TM receptor activity Deleted RELATION is a GO:0004888 (transmembrane signaling receptor activity)
2010-10-07 GO:0001623 Mas proto-oncogene receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001624 RDC1 receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001625 Epstein-Barr Virus-induced receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001628 gastropyloric receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0001622 super conserved receptor expressed in brain receptor activity Deleted RELATION is a GO:0004930 (G-protein coupled receptor activity)
2010-10-07 GO:0004435 phosphatidylinositol phospholipase C activity Deleted RELATION is a GO:0004434 (inositol or phosphatidylinositol phosphodiesterase activity)

Cross-references

Timestamp GO ID GO Term Name Action Category Detail
2010-10-07 GO:0004434 inositol or phosphatidylinositol phosphodiesterase activity Deleted XREF EC:3.1.4.-
2010-10-07 GO:0004713 protein tyrosine kinase activity Added XREF EC:2.7.11.-
2010-10-07 GO:0004718 Janus kinase activity Deleted XREF EC:2.7.11.-
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added XREF EC:3.1.4.-
2010-10-07 GO:0004986 delta-opioid receptor activity Added XREF Wikipedia:Delta_Opioid_receptor
2010-10-07 GO:0004988 mu-opioid receptor activity Added XREF Wikipedia:Mu_Opioid_receptor

Other

Timestamp GO ID GO Term Name Action Category Detail
2010-10-07 GO:0008081 phosphoric diester hydrolase activity Added SECONDARY GO:0004434 (inositol or phosphatidylinositol phosphodiesterase activity)
2010-10-07 GO:0004536 deoxyribonuclease activity Added SECONDARY GO:0004537 (caspase-activated deoxyribonuclease activity)
2010-10-07 GO:0004713 protein tyrosine kinase activity Added SECONDARY GO:0004718 (Janus kinase activity)
2010-10-07 GO:0004803 transposase activity Added SECONDARY GO:0004804 (P-element encoded transposase activity)
2010-10-07 GO:0004888 transmembrane signaling receptor activity Added SECONDARY GO:0004926 (non-G-protein coupled 7TM receptor activity)
2010-10-07 GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity Added SECONDARY GO:0004770 (sterol carrier protein X-related thiolase activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001625 (Epstein-Barr Virus-induced receptor activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001624 (RDC1 receptor activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001623 (Mas proto-oncogene receptor activity)
2010-10-07 GO:0004930 G-protein coupled receptor activity Added SECONDARY GO:0001622 (super conserved receptor expressed in brain receptor activity)
2010-10-07 GO:0004993 serotonin receptor activity Added SECONDARY GO:0016609 (G-protein coupled serotonin receptor activity)
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