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GO Term History: Displaying 70 audit records for all terms for the date 2010-05-02

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added RELATION is a GO:0035295 (tube development)
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added RELATION part of GO:0003338 (metanephros morphogenesis)
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added RELATION part of GO:0001657 (ureteric bud development)
2010-05-02 GO:0035503 ureter part of ureteric bud development Added RELATION part of GO:0072197 (ureter morphogenesis)
2010-05-02 GO:0035503 ureter part of ureteric bud development Added RELATION is a GO:0035295 (tube development)
2010-05-02 GO:0035503 ureter part of ureteric bud development Added RELATION part of GO:0001657 (ureteric bud development)
2010-05-02 GO:0046716 muscle cell cellular homeostasis Updated TERM muscle cell homeostasis
2010-05-02 GO:0035497 cAMP response element binding Added TERM cAMP response element binding
2010-05-02 GO:0035498 carnosine metabolic process Added TERM carnosine metabolic process
2010-05-02 GO:0035499 carnosine biosynthetic process Added TERM carnosine biosynthetic process
2010-05-02 GO:0035500 MH2 domain binding Added TERM MH2 domain binding
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added TERM adrenal chromaffin cell differentiation
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added TERM regulation of stomach neuroendocrine cell differentiation
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added TERM negative regulation of stomach neuroendocrine cell differentiation
2010-05-02 GO:0035501 MH1 domain binding Added TERM MH1 domain binding
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added TERM metanephric ureteric bud development
2010-05-02 GO:0035503 ureter part of ureteric bud development Added TERM ureter ureteric bud development
2010-05-02 GO:0035500 MH2 domain binding Added SYNONYM MAD homology 2 domain binding
2010-05-02 GO:0046716 muscle cell cellular homeostasis Added SYNONYM muscle homeostasis
2010-05-02 GO:0006200 ATP catabolic process Added SYNONYM ATP hydrolysis
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine synthesis
2010-05-02 GO:0035501 MH1 domain binding Added SYNONYM MAD homology 1 domain binding
2010-05-02 GO:0046716 muscle cell cellular homeostasis Added SYNONYM muscle fiber maintenance
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine anabolism
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cyclic-AMP-responsive element binding
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM CRE binding
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cyclic-AMP response element binding
2010-05-02 GO:0035498 carnosine metabolic process Added SYNONYM carnosine metabolism
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine biosynthesis
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine formation
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cAMP-responsive element binding
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cyclic AMP response element binding
2010-05-02 GO:0046716 muscle cell cellular homeostasis Deleted DEFINITION The cellular homeostatic process by which a muscle fiber is preserved in a stable functional or structural state.
2010-05-02 GO:0014896 muscle hypertrophy Deleted DEFINITION The enlargement or overgrowth of all or part of an organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
2010-05-02 GO:0030154 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-05-02 GO:0035498 carnosine metabolic process Added DEFINITION The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).
2010-05-02 GO:0035500 MH2 domain binding Added DEFINITION Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added DEFINITION Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added DEFINITION Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
2010-05-02 GO:0035501 MH1 domain binding Added DEFINITION Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added DEFINITION The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.
2010-05-02 GO:0014896 muscle hypertrophy Added DEFINITION The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
2010-05-02 GO:0035497 cAMP response element binding Added DEFINITION Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.
2010-05-02 GO:0035499 carnosine biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).
2010-05-02 GO:0035503 ureter part of ureteric bud development Added DEFINITION The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.
2010-05-02 GO:0046716 muscle cell cellular homeostasis Added DEFINITION The cellular homeostatic process by which a muscle cell is preserved in a stable functional or structural state.
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.
2010-05-02 GO:0030154 cell differentiation Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-05-02 GO:0006200 ATP catabolic process Deleted SYNONYM ATP hydrolysis
2010-05-02 GO:0046716 muscle cell cellular homeostasis Deleted SYNONYM muscle fiber maintenance
2010-05-02 GO:0019674 NAD metabolic process Deleted RELATION is a GO:0006769 (nicotinamide metabolic process)
2010-05-02 GO:0006739 NADP metabolic process Deleted RELATION is a GO:0006769 (nicotinamide metabolic process)
2010-05-02 GO:0001657 ureteric bud development Deleted RELATION part of GO:0001656 (metanephros development)
2010-05-02 GO:0072007 mesangial cell differentiation Deleted RELATION is a GO:0001822 (kidney development)
2010-05-02 GO:0072268 pattern specification involved in metanephros development Added RELATION part of GO:0001656 (metanephros development)
2010-05-02 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development Added RELATION is a GO:0072268 (pattern specification involved in metanephros development)
2010-05-02 GO:0072293 specification of metanephric nephron tubule identity Added RELATION part of GO:0072268 (pattern specification involved in metanephros development)
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added RELATION is a GO:0061101 (neuroendocrine cell differentiation)
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added RELATION part of GO:0030325 (adrenal gland development)
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added RELATION regulates GO:0061102 (stomach neuroendocrine cell differentiation)
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added RELATION is a GO:0045595 (regulation of cell differentiation)
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added RELATION is a GO:0061105 (regulation of stomach neuroendocrine cell differentiation)
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added RELATION negatively regulates GO:0061102 (stomach neuroendocrine cell differentiation)
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added RELATION is a GO:0045596 (negative regulation of cell differentiation)
2010-05-02 GO:0035497 cAMP response element binding Added RELATION is a GO:0010843 (promoter binding)
2010-05-02 GO:0035498 carnosine metabolic process Added RELATION is a GO:0006575 (cellular modified amino acid metabolic process)
2010-05-02 GO:0035499 carnosine biosynthetic process Added RELATION is a GO:0042398 (cellular modified amino acid biosynthetic process)
2010-05-02 GO:0035499 carnosine biosynthetic process Added RELATION is a GO:0035498 (carnosine metabolic process)
2010-05-02 GO:0035500 MH2 domain binding Added RELATION is a GO:0019904 (protein domain specific binding)
2010-05-02 GO:0035501 MH1 domain binding Added RELATION is a GO:0019904 (protein domain specific binding)

Terms

Timestamp GO ID GO Term Name Action Category Detail
2010-05-02 GO:0046716 muscle cell cellular homeostasis Updated TERM muscle cell homeostasis
2010-05-02 GO:0035497 cAMP response element binding Added TERM cAMP response element binding
2010-05-02 GO:0035498 carnosine metabolic process Added TERM carnosine metabolic process
2010-05-02 GO:0035499 carnosine biosynthetic process Added TERM carnosine biosynthetic process
2010-05-02 GO:0035500 MH2 domain binding Added TERM MH2 domain binding
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added TERM adrenal chromaffin cell differentiation
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added TERM regulation of stomach neuroendocrine cell differentiation
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added TERM negative regulation of stomach neuroendocrine cell differentiation
2010-05-02 GO:0035501 MH1 domain binding Added TERM MH1 domain binding
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added TERM metanephric ureteric bud development
2010-05-02 GO:0035503 ureter part of ureteric bud development Added TERM ureter ureteric bud development

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2010-05-02 GO:0035500 MH2 domain binding Added SYNONYM MAD homology 2 domain binding
2010-05-02 GO:0046716 muscle cell cellular homeostasis Added SYNONYM muscle homeostasis
2010-05-02 GO:0006200 ATP catabolic process Added SYNONYM ATP hydrolysis
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine synthesis
2010-05-02 GO:0035501 MH1 domain binding Added SYNONYM MAD homology 1 domain binding
2010-05-02 GO:0046716 muscle cell cellular homeostasis Added SYNONYM muscle fiber maintenance
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine anabolism
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cyclic-AMP-responsive element binding
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM CRE binding
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cyclic-AMP response element binding
2010-05-02 GO:0035498 carnosine metabolic process Added SYNONYM carnosine metabolism
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine biosynthesis
2010-05-02 GO:0035499 carnosine biosynthetic process Added SYNONYM carnosine formation
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cAMP-responsive element binding
2010-05-02 GO:0035497 cAMP response element binding Added SYNONYM cyclic AMP response element binding
2010-05-02 GO:0046716 muscle cell cellular homeostasis Deleted DEFINITION The cellular homeostatic process by which a muscle fiber is preserved in a stable functional or structural state.
2010-05-02 GO:0014896 muscle hypertrophy Deleted DEFINITION The enlargement or overgrowth of all or part of an organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
2010-05-02 GO:0030154 cell differentiation Deleted DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2010-05-02 GO:0035498 carnosine metabolic process Added DEFINITION The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).
2010-05-02 GO:0035500 MH2 domain binding Added DEFINITION Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added DEFINITION Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added DEFINITION Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
2010-05-02 GO:0035501 MH1 domain binding Added DEFINITION Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added DEFINITION The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.
2010-05-02 GO:0014896 muscle hypertrophy Added DEFINITION The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
2010-05-02 GO:0035497 cAMP response element binding Added DEFINITION Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.
2010-05-02 GO:0035499 carnosine biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).
2010-05-02 GO:0035503 ureter part of ureteric bud development Added DEFINITION The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.
2010-05-02 GO:0046716 muscle cell cellular homeostasis Added DEFINITION The cellular homeostatic process by which a muscle cell is preserved in a stable functional or structural state.
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.
2010-05-02 GO:0030154 cell differentiation Added DEFINITION The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
2010-05-02 GO:0006200 ATP catabolic process Deleted SYNONYM ATP hydrolysis
2010-05-02 GO:0046716 muscle cell cellular homeostasis Deleted SYNONYM muscle fiber maintenance

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added RELATION is a GO:0035295 (tube development)
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added RELATION part of GO:0003338 (metanephros morphogenesis)
2010-05-02 GO:0035502 metanephric part of ureteric bud development Added RELATION part of GO:0001657 (ureteric bud development)
2010-05-02 GO:0035503 ureter part of ureteric bud development Added RELATION part of GO:0072197 (ureter morphogenesis)
2010-05-02 GO:0035503 ureter part of ureteric bud development Added RELATION is a GO:0035295 (tube development)
2010-05-02 GO:0035503 ureter part of ureteric bud development Added RELATION part of GO:0001657 (ureteric bud development)
2010-05-02 GO:0019674 NAD metabolic process Deleted RELATION is a GO:0006769 (nicotinamide metabolic process)
2010-05-02 GO:0006739 NADP metabolic process Deleted RELATION is a GO:0006769 (nicotinamide metabolic process)
2010-05-02 GO:0001657 ureteric bud development Deleted RELATION part of GO:0001656 (metanephros development)
2010-05-02 GO:0072007 mesangial cell differentiation Deleted RELATION is a GO:0001822 (kidney development)
2010-05-02 GO:0072268 pattern specification involved in metanephros development Added RELATION part of GO:0001656 (metanephros development)
2010-05-02 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development Added RELATION is a GO:0072268 (pattern specification involved in metanephros development)
2010-05-02 GO:0072293 specification of metanephric nephron tubule identity Added RELATION part of GO:0072268 (pattern specification involved in metanephros development)
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added RELATION is a GO:0061101 (neuroendocrine cell differentiation)
2010-05-02 GO:0061104 adrenal chromaffin cell differentiation Added RELATION part of GO:0030325 (adrenal gland development)
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added RELATION regulates GO:0061102 (stomach neuroendocrine cell differentiation)
2010-05-02 GO:0061105 regulation of stomach neuroendocrine cell differentiation Added RELATION is a GO:0045595 (regulation of cell differentiation)
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added RELATION is a GO:0061105 (regulation of stomach neuroendocrine cell differentiation)
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added RELATION negatively regulates GO:0061102 (stomach neuroendocrine cell differentiation)
2010-05-02 GO:0061106 negative regulation of stomach neuroendocrine cell differentiation Added RELATION is a GO:0045596 (negative regulation of cell differentiation)
2010-05-02 GO:0035497 cAMP response element binding Added RELATION is a GO:0010843 (promoter binding)
2010-05-02 GO:0035498 carnosine metabolic process Added RELATION is a GO:0006575 (cellular modified amino acid metabolic process)
2010-05-02 GO:0035499 carnosine biosynthetic process Added RELATION is a GO:0042398 (cellular modified amino acid biosynthetic process)
2010-05-02 GO:0035499 carnosine biosynthetic process Added RELATION is a GO:0035498 (carnosine metabolic process)
2010-05-02 GO:0035500 MH2 domain binding Added RELATION is a GO:0019904 (protein domain specific binding)
2010-05-02 GO:0035501 MH1 domain binding Added RELATION is a GO:0019904 (protein domain specific binding)
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