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GO Term History: Displaying 101 audit records for all terms for the date 2010-01-14

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2010-01-14 GO:0071542 dopaminergic neuron differentiation Added RELATION is a GO:0030182 (neuron differentiation)
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added RELATION is a GO:0043647 (inositol phosphate metabolic process)
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added RELATION is a GO:0071545 (inositol phosphate catabolic process)
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added RELATION is a GO:0071543 (diphosphoinositol polyphosphate metabolic process)
2010-01-14 GO:0071545 inositol phosphate catabolic process Added RELATION is a GO:0043647 (inositol phosphate metabolic process)
2010-01-14 GO:0071545 inositol phosphate catabolic process Added RELATION is a GO:0019310 (inositol catabolic process)
2010-01-14 GO:0071546 pi-body Added RELATION is a GO:0043186 (P granule)
2010-01-14 GO:0071547 piP-body Added RELATION is a GO:0043186 (P granule)
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090215 (regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added RELATION is a GO:0045834 (positive regulation of lipid metabolic process)
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added RELATION is a GO:0043550 (regulation of lipid kinase activity)
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added RELATION is a GO:0033674 (positive regulation of kinase activity)
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added RELATION is a GO:0045833 (negative regulation of lipid metabolic process)
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added RELATION is a GO:0043550 (regulation of lipid kinase activity)
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added RELATION is a GO:0033673 (negative regulation of kinase activity)
2010-01-14 GO:0090215 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0043550 (regulation of lipid kinase activity)
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090218 (positive regulation of lipid kinase activity)
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090215 (regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090219 (negative regulation of lipid kinase activity)
2010-01-14 GO:0071539 protein localization to centrosome Added RELATION is a GO:0033365 (protein localization to organelle)
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added RELATION is a GO:0005852 (eukaryotic translation initiation factor 3 complex)
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added RELATION is a GO:0005852 (eukaryotic translation initiation factor 3 complex)
2010-01-14 GO:0045047 protein targeting to ER Added RELATION part of GO:0071539 (protein localization to centrosome)
2010-01-14 GO:0044232 organelle membrane contact site Added RELATION is a GO:0044422 (organelle part)
2010-01-14 GO:0044232 organelle membrane contact site Added RELATION part of GO:0031090 (organelle membrane)
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added RELATION is a GO:0044232 (organelle membrane contact site)
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added RELATION part of GO:0031966 (mitochondrial membrane)
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added RELATION part of GO:0005789 (endoplasmic reticulum membrane)
2010-01-14 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity Added RELATION is a GO:0090218 (positive regulation of lipid kinase activity)
2010-01-14 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity Deleted RELATION is a GO:0033674 (positive regulation of kinase activity)
2010-01-14 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity Added RELATION is a GO:0090219 (negative regulation of lipid kinase activity)
2010-01-14 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity Deleted RELATION is a GO:0033673 (negative regulation of kinase activity)
2010-01-14 GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity Added RELATION is a GO:0090218 (positive regulation of lipid kinase activity)
2010-01-14 GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity Deleted RELATION is a GO:0033674 (positive regulation of kinase activity)
2010-01-14 GO:0043127 negative regulation of 1-phosphatidylinositol 4-kinase activity Added RELATION is a GO:0090219 (negative regulation of lipid kinase activity)
2010-01-14 GO:0043127 negative regulation of 1-phosphatidylinositol 4-kinase activity Deleted RELATION is a GO:0033673 (negative regulation of kinase activity)
2010-01-14 GO:0032865 ERMES complex Added RELATION part of GO:0044233 (ER-mitochondrion membrane contact site)
2010-01-14 GO:0032865 ERMES complex Added SYNONYM ER-mitochondria encounter structure
2010-01-14 GO:0016241 regulation of macroautophagy Added SYNONYM regulation of starvation-induced autophagy
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added SYNONYM eIF3e-containing eukaryotic translation initiation factor 3 complex
2010-01-14 GO:0071546 pi-body Added SYNONYM intermitochondrial cement
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added SYNONYM diphosphoinositol polyphosphate breakdown
2010-01-14 GO:0016242 negative regulation of macroautophagy Added SYNONYM negative regulation of starvation-induced autophagy
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added SYNONYM diphosphoinositol polyphosphate catabolism
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added SYNONYM diphosphoinositol polyphosphate degradation
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM inositol phosphate breakdown
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM myo-inositol phosphate catabolic process
2010-01-14 GO:0071459 protein localization to chromosome, centromeric region Deleted SYNONYM protein localization to chromosome, centromeric region
2010-01-14 GO:0070198 protein localization to chromosome, telomeric region Deleted SYNONYM protein localization to chromosome, telomeric region
2010-01-14 GO:0044232 organelle membrane contact site Added SYNONYM MCS
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added SYNONYM diphosphoinositol polyphosphate metabolism
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM inositol phosphate degradation
2010-01-14 GO:0032865 ERMES complex Added SYNONYM Mdm10/Mdm12/Mmm1 complex
2010-01-14 GO:0070198 protein localization to chromosome, telomeric region Added SYNONYM protein localization to telomere
2010-01-14 GO:0044232 organelle membrane contact site Added SYNONYM inter-organelle junction
2010-01-14 GO:0044232 organelle membrane contact site Added SYNONYM interorganelle junction
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added SYNONYM eIF3m-containing eukaryotic translation initiation factor 3 complex
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM inositol phosphate catabolism
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added SYNONYM endoplasmic-reticulum-mitochondrion membrane contact site
2010-01-14 GO:0071459 protein localization to chromosome, centromeric region Added SYNONYM protein localization to centromere
2010-01-14 GO:0016236 macroautophagy Added SYNONYM starvation-induced autophagy
2010-01-14 GO:0016239 positive regulation of macroautophagy Added SYNONYM positive regulation of starvation-induced autophagy
2010-01-14 GO:0032865 ERMES complex Deleted DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2010-01-14 GO:0005852 eukaryotic translation initiation factor 3 complex Deleted DEFINITION A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex.
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added DEFINITION An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.
2010-01-14 GO:0071542 dopaminergic neuron differentiation Added DEFINITION The process whereby a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added DEFINITION Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
2010-01-14 GO:0071547 piP-body Added DEFINITION A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
2010-01-14 GO:0005852 eukaryotic translation initiation factor 3 complex Added DEFINITION A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added DEFINITION A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added DEFINITION An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.
2010-01-14 GO:0032865 ERMES complex Added DEFINITION A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth.
2010-01-14 GO:0044232 organelle membrane contact site Added DEFINITION A zone of apposition between the membranes of two organelles, structured by bridging complexes. Membrane contact sites (MCSs) are specialised for communication, in particular the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
2010-01-14 GO:0071539 protein localization to centrosome Added DEFINITION A process by which a protein is transported to, or maintained at, the centrosome.
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added DEFINITION The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
2010-01-14 GO:0071545 inositol phosphate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
2010-01-14 GO:0090215 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added DEFINITION Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
2010-01-14 GO:0071546 pi-body Added DEFINITION A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added DEFINITION Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added DEFINITION Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added DEFINITION Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added TERM positive regulation of lipid kinase activity
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added TERM negative regulation of lipid kinase activity
2010-01-14 GO:0044232 organelle membrane contact site Added TERM organelle membrane contact site
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added TERM ER-mitochondrion membrane contact site
2010-01-14 GO:0032865 ERMES complex Updated TERM ERMES complex
2010-01-14 GO:0070198 protein localization to chromosome, telomeric region Updated TERM protein localization to chromosome, telomeric region
2010-01-14 GO:0071539 protein localization to centrosome Added TERM protein localization to centrosome
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added TERM eukaryotic translation initiation factor 3 complex, eIF3e
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added TERM eukaryotic translation initiation factor 3 complex, eIF3m
2010-01-14 GO:0071542 dopaminergic neuron differentiation Added TERM dopaminergic neuron differentiation
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added TERM diphosphoinositol polyphosphate metabolic process
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added TERM diphosphoinositol polyphosphate catabolic process
2010-01-14 GO:0071545 inositol phosphate catabolic process Added TERM inositol phosphate catabolic process
2010-01-14 GO:0071546 pi-body Added TERM pi-body
2010-01-14 GO:0071547 piP-body Added TERM piP-body
2010-01-14 GO:0071459 protein localization to chromosome, centromeric region Updated TERM protein localization to chromosome, centromeric region
2010-01-14 GO:0090215 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added TERM regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added TERM positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added TERM negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity

Terms

Timestamp GO ID GO Term Name Action Category Detail
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added TERM positive regulation of lipid kinase activity
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added TERM negative regulation of lipid kinase activity
2010-01-14 GO:0044232 organelle membrane contact site Added TERM organelle membrane contact site
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added TERM ER-mitochondrion membrane contact site
2010-01-14 GO:0032865 ERMES complex Updated TERM ERMES complex
2010-01-14 GO:0070198 protein localization to chromosome, telomeric region Updated TERM protein localization to chromosome, telomeric region
2010-01-14 GO:0071539 protein localization to centrosome Added TERM protein localization to centrosome
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added TERM eukaryotic translation initiation factor 3 complex, eIF3e
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added TERM eukaryotic translation initiation factor 3 complex, eIF3m
2010-01-14 GO:0071542 dopaminergic neuron differentiation Added TERM dopaminergic neuron differentiation
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added TERM diphosphoinositol polyphosphate metabolic process
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added TERM diphosphoinositol polyphosphate catabolic process
2010-01-14 GO:0071545 inositol phosphate catabolic process Added TERM inositol phosphate catabolic process
2010-01-14 GO:0071546 pi-body Added TERM pi-body
2010-01-14 GO:0071547 piP-body Added TERM piP-body
2010-01-14 GO:0071459 protein localization to chromosome, centromeric region Updated TERM protein localization to chromosome, centromeric region
2010-01-14 GO:0090215 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added TERM regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added TERM positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added TERM negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2010-01-14 GO:0032865 ERMES complex Added SYNONYM ER-mitochondria encounter structure
2010-01-14 GO:0016241 regulation of macroautophagy Added SYNONYM regulation of starvation-induced autophagy
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added SYNONYM eIF3e-containing eukaryotic translation initiation factor 3 complex
2010-01-14 GO:0071546 pi-body Added SYNONYM intermitochondrial cement
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added SYNONYM diphosphoinositol polyphosphate breakdown
2010-01-14 GO:0016242 negative regulation of macroautophagy Added SYNONYM negative regulation of starvation-induced autophagy
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added SYNONYM diphosphoinositol polyphosphate catabolism
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added SYNONYM diphosphoinositol polyphosphate degradation
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM inositol phosphate breakdown
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM myo-inositol phosphate catabolic process
2010-01-14 GO:0071459 protein localization to chromosome, centromeric region Deleted SYNONYM protein localization to chromosome, centromeric region
2010-01-14 GO:0070198 protein localization to chromosome, telomeric region Deleted SYNONYM protein localization to chromosome, telomeric region
2010-01-14 GO:0044232 organelle membrane contact site Added SYNONYM MCS
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added SYNONYM diphosphoinositol polyphosphate metabolism
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM inositol phosphate degradation
2010-01-14 GO:0032865 ERMES complex Added SYNONYM Mdm10/Mdm12/Mmm1 complex
2010-01-14 GO:0070198 protein localization to chromosome, telomeric region Added SYNONYM protein localization to telomere
2010-01-14 GO:0044232 organelle membrane contact site Added SYNONYM inter-organelle junction
2010-01-14 GO:0044232 organelle membrane contact site Added SYNONYM interorganelle junction
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added SYNONYM eIF3m-containing eukaryotic translation initiation factor 3 complex
2010-01-14 GO:0071545 inositol phosphate catabolic process Added SYNONYM inositol phosphate catabolism
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added SYNONYM endoplasmic-reticulum-mitochondrion membrane contact site
2010-01-14 GO:0071459 protein localization to chromosome, centromeric region Added SYNONYM protein localization to centromere
2010-01-14 GO:0016236 macroautophagy Added SYNONYM starvation-induced autophagy
2010-01-14 GO:0016239 positive regulation of macroautophagy Added SYNONYM positive regulation of starvation-induced autophagy
2010-01-14 GO:0032865 ERMES complex Deleted DEFINITION A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system.
2010-01-14 GO:0005852 eukaryotic translation initiation factor 3 complex Deleted DEFINITION A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex.
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added DEFINITION An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.
2010-01-14 GO:0071542 dopaminergic neuron differentiation Added DEFINITION The process whereby a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added DEFINITION Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
2010-01-14 GO:0071547 piP-body Added DEFINITION A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
2010-01-14 GO:0005852 eukaryotic translation initiation factor 3 complex Added DEFINITION A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added DEFINITION A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added DEFINITION An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.
2010-01-14 GO:0032865 ERMES complex Added DEFINITION A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth.
2010-01-14 GO:0044232 organelle membrane contact site Added DEFINITION A zone of apposition between the membranes of two organelles, structured by bridging complexes. Membrane contact sites (MCSs) are specialised for communication, in particular the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
2010-01-14 GO:0071539 protein localization to centrosome Added DEFINITION A process by which a protein is transported to, or maintained at, the centrosome.
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added DEFINITION The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
2010-01-14 GO:0071545 inositol phosphate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
2010-01-14 GO:0090215 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added DEFINITION Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
2010-01-14 GO:0071546 pi-body Added DEFINITION A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added DEFINITION Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added DEFINITION Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added DEFINITION Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2010-01-14 GO:0071542 dopaminergic neuron differentiation Added RELATION is a GO:0030182 (neuron differentiation)
2010-01-14 GO:0071543 diphosphoinositol polyphosphate metabolic process Added RELATION is a GO:0043647 (inositol phosphate metabolic process)
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added RELATION is a GO:0071545 (inositol phosphate catabolic process)
2010-01-14 GO:0071544 diphosphoinositol polyphosphate catabolic process Added RELATION is a GO:0071543 (diphosphoinositol polyphosphate metabolic process)
2010-01-14 GO:0071545 inositol phosphate catabolic process Added RELATION is a GO:0043647 (inositol phosphate metabolic process)
2010-01-14 GO:0071545 inositol phosphate catabolic process Added RELATION is a GO:0019310 (inositol catabolic process)
2010-01-14 GO:0071546 pi-body Added RELATION is a GO:0043186 (P granule)
2010-01-14 GO:0071547 piP-body Added RELATION is a GO:0043186 (P granule)
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090215 (regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added RELATION is a GO:0045834 (positive regulation of lipid metabolic process)
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added RELATION is a GO:0043550 (regulation of lipid kinase activity)
2010-01-14 GO:0090218 positive regulation of lipid kinase activity Added RELATION is a GO:0033674 (positive regulation of kinase activity)
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added RELATION is a GO:0045833 (negative regulation of lipid metabolic process)
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added RELATION is a GO:0043550 (regulation of lipid kinase activity)
2010-01-14 GO:0090219 negative regulation of lipid kinase activity Added RELATION is a GO:0033673 (negative regulation of kinase activity)
2010-01-14 GO:0090215 regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0043550 (regulation of lipid kinase activity)
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090218 (positive regulation of lipid kinase activity)
2010-01-14 GO:0090216 positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090215 (regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)
2010-01-14 GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity Added RELATION is a GO:0090219 (negative regulation of lipid kinase activity)
2010-01-14 GO:0071539 protein localization to centrosome Added RELATION is a GO:0033365 (protein localization to organelle)
2010-01-14 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e Added RELATION is a GO:0005852 (eukaryotic translation initiation factor 3 complex)
2010-01-14 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m Added RELATION is a GO:0005852 (eukaryotic translation initiation factor 3 complex)
2010-01-14 GO:0045047 protein targeting to ER Added RELATION part of GO:0071539 (protein localization to centrosome)
2010-01-14 GO:0044232 organelle membrane contact site Added RELATION is a GO:0044422 (organelle part)
2010-01-14 GO:0044232 organelle membrane contact site Added RELATION part of GO:0031090 (organelle membrane)
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added RELATION is a GO:0044232 (organelle membrane contact site)
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added RELATION part of GO:0031966 (mitochondrial membrane)
2010-01-14 GO:0044233 ER-mitochondrion membrane contact site Added RELATION part of GO:0005789 (endoplasmic reticulum membrane)
2010-01-14 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity Added RELATION is a GO:0090218 (positive regulation of lipid kinase activity)
2010-01-14 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity Deleted RELATION is a GO:0033674 (positive regulation of kinase activity)
2010-01-14 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity Added RELATION is a GO:0090219 (negative regulation of lipid kinase activity)
2010-01-14 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity Deleted RELATION is a GO:0033673 (negative regulation of kinase activity)
2010-01-14 GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity Added RELATION is a GO:0090218 (positive regulation of lipid kinase activity)
2010-01-14 GO:0043128 positive regulation of 1-phosphatidylinositol 4-kinase activity Deleted RELATION is a GO:0033674 (positive regulation of kinase activity)
2010-01-14 GO:0043127 negative regulation of 1-phosphatidylinositol 4-kinase activity Added RELATION is a GO:0090219 (negative regulation of lipid kinase activity)
2010-01-14 GO:0043127 negative regulation of 1-phosphatidylinositol 4-kinase activity Deleted RELATION is a GO:0033673 (negative regulation of kinase activity)
2010-01-14 GO:0032865 ERMES complex Added RELATION part of GO:0044233 (ER-mitochondrion membrane contact site)
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