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GO Term History: Displaying 500 audit records for all terms for the date 2009-07-03

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2009-07-03 GO:0006948 induction by virus of host cell-cell fusion Updated TERM induction by virus of host cell-cell fusion
2009-07-03 GO:0006018 2-deoxyribose 1-phosphate catabolic process Updated TERM 2-deoxyribose 1-phosphate catabolic process
2009-07-03 GO:0030581 symbiont intracellular protein transport in host Updated TERM symbiont intracellular protein transport in host
2009-07-03 GO:0044000 movement in host Updated TERM movement in host
2009-07-03 GO:0044001 migration in host Updated TERM migration in host
2009-07-03 GO:0033665 regulation of growth or development of symbiont in host Updated TERM regulation of growth or development of symbiont in host
2009-07-03 GO:0033666 positive regulation of growth or development of symbiont in host Updated TERM positive regulation of growth or development of symbiont in host
2009-07-03 GO:0033667 negative regulation of growth or development of symbiont in host Updated TERM negative regulation of growth or development of symbiont in host
2009-07-03 GO:0052242 chemotaxis in other organism involved in symbiotic interaction Updated TERM chemotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052244 negative energy taxis in other organism involved in symbiotic interaction Updated TERM negative energy taxis in other organism during symbiotic interaction
2009-07-03 GO:0052247 positive energy taxis in other organism involved in symbiotic interaction Updated TERM positive energy taxis in other organism during symbiotic interaction
2009-07-03 GO:0052334 modification by organism of cytoskeleton of other organism involved in symbiotic interaction Updated TERM modification by organism of cytoskeleton of other organism during symbiotic interaction
2009-07-03 GO:0052533 positive regulation by symbiont of host induced systemic resistance Updated TERM positive regulation by symbiont of host induced systemic resistance
2009-07-03 GO:0052537 positive regulation by symbiont of host systemic acquired resistance Updated TERM positive regulation by symbiont of host systemic acquired resistance
2009-07-03 GO:0052018 modulation by symbiont of RNA levels in host Updated TERM modulation by symbiont of RNA levels in host
2009-07-03 GO:0052103 induction by symbiont of host induced systemic resistance Updated TERM induction by symbiont of host induced systemic resistance
2009-07-03 GO:0052104 induction by symbiont of host systemic acquired resistance Updated TERM induction by symbiont of host systemic acquired resistance
2009-07-03 GO:0052133 positive aerotaxis in host Updated TERM positive aerotaxis in host
2009-07-03 GO:0052135 negative aerotaxis in host Updated TERM negative aerotaxis in host
2009-07-03 GO:0052137 aerotaxis in host Updated TERM aerotaxis in host
2009-07-03 GO:0052139 negative chemotaxis in host Updated TERM negative chemotaxis in host
2009-07-03 GO:0052140 positive chemotaxis in host Updated TERM positive chemotaxis in host
2009-07-03 GO:0052144 negative energy taxis in host Updated TERM negative energy taxis in host
2009-07-03 GO:0052147 positive energy taxis in host Updated TERM positive energy taxis in host
2009-07-03 GO:0052159 modulation by symbiont of host induced systemic resistance Updated TERM modulation by symbiont of host induced systemic resistance
2009-07-03 GO:0052160 modulation by symbiont of host systemic acquired resistance Updated TERM modulation by symbiont of host systemic acquired resistance
2009-07-03 GO:0052224 energy taxis in other organism involved in symbiotic interaction Updated TERM energy taxis in other organism during symbiotic interaction
2009-07-03 GO:0052233 positive aerotaxis in other organism involved in symbiotic interaction Updated TERM positive aerotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052235 negative aerotaxis in other organism involved in symbiotic interaction Updated TERM negative aerotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052237 aerotaxis in other organism involved in symbiotic interaction Updated TERM aerotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052239 negative chemotaxis in other organism involved in symbiotic interaction Updated TERM negative chemotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052240 positive chemotaxis in other organism involved in symbiotic interaction Updated TERM positive chemotaxis in other organism during symbiotic interaction
2009-07-03 GO:0051814 movement in other organism involved in symbiotic interaction Updated TERM movement in other organism during symbiotic interaction
2009-07-03 GO:0051815 migration in other organism involved in symbiotic interaction Updated TERM migration in other organism during symbiotic interaction
2009-07-03 GO:0051831 growth or development in other organism during symbiotic interaction Updated TERM growth or development in other organism during symbiotic interaction
2009-07-03 GO:0046388 deoxyribose 1-phosphate metabolic process Deleted TERM deoxyribose 1-phosphate metabolic process
2009-07-03 GO:0046733 passive induction of host humoral immune response by virus Updated TERM passive induction of host humoral immune response by virus
2009-07-03 GO:0046734 passive induction of host cell-mediated immune response by virus Updated TERM passive induction of host cell-mediated immune response by virus
2009-07-03 GO:0046735 passive induction of host innate immune response by virus Updated TERM passive induction of host innate immune response by virus
2009-07-03 GO:0046739 transport of virus in multicellular host Updated TERM spread of virus in host
2009-07-03 GO:0046740 transport of virus in host, cell to cell Updated TERM spread of virus in host, cell to cell
2009-07-03 GO:0046741 transport of virus in host, tissue to tissue Updated TERM spread of virus in host, tissue to tissue
2009-07-03 GO:0046774 suppression by virus of host intracellular interferon activity Updated TERM suppression by virus of host intracellular interferon activity
2009-07-03 GO:0046776 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Updated TERM suppression by virus of host MHC class I cell surface presentation
2009-07-03 GO:0044412 growth or development of symbiont in host Updated TERM growth or development of symbiont in host
2009-07-03 GO:0070359 actin polymerization-dependent cell motility involved in migration of symbiont in host Updated TERM actin polymerization-dependent cell motility involved in migration of symbiont in host
2009-07-03 GO:0070772 PAS complex Added TERM PAS complex
2009-07-03 GO:0070773 protein-N-terminal glutamine amidohydrolase activity Added TERM protein N-terminal glutamine amidohydrolase activity
2009-07-03 GO:0070774 phytoceramidase activity Added TERM phytoceramidase activity
2009-07-03 GO:0070775 H3 histone acetyltransferase complex Added TERM H3 histone acetyltransferase complex
2009-07-03 GO:0070776 MOZ/MORF histone acetyltransferase complex Added TERM MOZ/MORF histone acetyltransferase complex
2009-07-03 GO:0070777 D-aspartate transport Added TERM D-aspartate transport
2009-07-03 GO:0070778 L-aspartate transport Added TERM L-aspartate transport
2009-07-03 GO:0070779 D-aspartate import Added TERM D-aspartate import
2009-07-03 GO:0070780 dihydrosphingosine-1-phosphate phosphatase activity Added TERM dihydrosphingosine-1-phosphate phosphatase activity
2009-07-03 GO:0070781 response to biotin Added TERM response to biotin
2009-07-03 GO:0070782 phosphatidylserine exposure on apoptotic cell surface Added TERM phosphatidylserine exposure on apoptotic cell surface
2009-07-03 GO:0075061 formation of symbiont invasive hypha in host Updated TERM formation of symbiont invasive hypha in host
2009-07-03 GO:0075062 regulation of symbiont invasive hypha formation in host Updated TERM regulation of symbiont invasive hypha formation in host
2009-07-03 GO:0075063 positive regulation of symbiont invasive hypha formation in host Updated TERM positive regulation of symbiont invasive hypha formation in host
2009-07-03 GO:0075064 negative regulation of symbiont invasive hypha formation in host Updated TERM negative regulation of symbiont invasive hypha formation in host
2009-07-03 GO:0048029 monosaccharide binding Deleted DEFINITION Interacting selectively with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
2009-07-03 GO:0050662 coenzyme binding Deleted DEFINITION Interacting selectively with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
2009-07-03 GO:0000401 open form four-way junction DNA binding Deleted DEFINITION Interacting selectively with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.
2009-07-03 GO:0031723 CXCR4 chemokine receptor binding Deleted DEFINITION Interacting selectively with a CXCR4 chemokine receptor.
2009-07-03 GO:0031755 Edg-2 lysophosphatidic acid receptor binding Deleted DEFINITION Interacting selectively with an Edg-2 lysophosphatidic acid receptor.
2009-07-03 GO:0031750 D3 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D3 dopamine receptor.
2009-07-03 GO:0045236 CXCR chemokine receptor binding Deleted DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2009-07-03 GO:0070742 C2H2 zinc finger domain binding Deleted DEFINITION Interacting selectively with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
2009-07-03 GO:0051375 FATZ 2 binding Deleted DEFINITION Interacting selectively with FATZ 2, a protein of the FATZ family that is highly expressed in skeletal muscle fiber fast IIa and slow I and in cardiac muscle.
2009-07-03 GO:0031855 oxytocin receptor binding Deleted DEFINITION Interacting selectively with an oxytocin receptor.
2009-07-03 GO:0031811 G-protein coupled nucleotide receptor binding Deleted DEFINITION Interacting selectively with a metabotropic nucleotide receptor.
2009-07-03 GO:0070095 fructose-6-phosphate binding Deleted DEFINITION Interacting selectively with fructose 6-phosphate.
2009-07-03 GO:0043531 ADP binding Deleted DEFINITION Interacting selectively with ADP, adenosine 5'-diphosphate.
2009-07-03 GO:0042806 fucose binding Deleted DEFINITION Interacting selectively with fucose, the pentose 6-deoxygalactose.
2009-07-03 GO:0046870 cadmium ion binding Deleted DEFINITION Interacting selectively with cadmium (Cd) ions.
2009-07-03 GO:0042562 hormone binding Deleted DEFINITION Interacting selectively with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
2009-07-03 GO:0051528 NFAT3 protein binding Deleted DEFINITION Interacting selectively with NFAT3 (nuclear factor of activated T cells 3 protein), a calcium-regulated protein which acts as a transcription factor.
2009-07-03 GO:0035091 phosphatidylinositol binding Deleted DEFINITION Interacting selectively with any inositol-containing glycerophospholipid.
2009-07-03 GO:0031803 type 6 metabotropic glutamate receptor binding Deleted DEFINITION Interacting selectively with a type 6 metabotropic glutamate receptor.
2009-07-03 GO:0031418 L-ascorbic acid binding Deleted DEFINITION Interacting selectively with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
2009-07-03 GO:0005111 type 2 fibroblast growth factor receptor binding Deleted DEFINITION Interacting selectively with the type 2 fibroblast growth factor receptor (FGFR2).
2009-07-03 GO:0005175 CD27 receptor binding Deleted DEFINITION Interacting selectively with a CD27, a receptor found on the surface of T cells and some B cells and NK cells.
2009-07-03 GO:0031473 myosin III binding Deleted DEFINITION Interacting selectively with a class III myosin; myosin III is monomeric and has an N terminal kinase domain.
2009-07-03 GO:0008017 microtubule binding Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2009-07-03 GO:0045510 interleukin-24 binding Deleted DEFINITION Interacting selectively with interleukin-24.
2009-07-03 GO:0031768 ghrelin receptor binding Deleted DEFINITION Interacting selectively with a ghrelin receptor.
2009-07-03 GO:0031701 angiotensin receptor binding Deleted DEFINITION Interacting selectively with an angiotensin receptor.
2009-07-03 GO:0031733 CCR8 chemokine receptor binding Deleted DEFINITION Interacting selectively with a CCR8 chemokine receptor.
2009-07-03 GO:0005169 neurotrophin TRKB receptor binding Deleted DEFINITION Interacting selectively with the neurotrophin TRKB receptor.
2009-07-03 GO:0005506 iron ion binding Deleted DEFINITION Interacting selectively with iron (Fe) ions.
2009-07-03 GO:0042923 neuropeptide binding Deleted DEFINITION Interacting selectively and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).
2009-07-03 GO:0032190 acrosin binding Deleted DEFINITION Interacting selectively with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.
2009-07-03 GO:0008097 5S rRNA binding Deleted DEFINITION Interacting selectively with 5S ribosomal RNA, the smallest RNA constituent of a ribosome.
2009-07-03 GO:0031751 D4 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D4 dopamine receptor.
2009-07-03 GO:0033295 hydroxyectoine binding Deleted DEFINITION Interacting selectively with hydroxyectoine.
2009-07-03 GO:0031864 EP1 subtype prostaglandin E2 receptor binding Deleted DEFINITION Interacting selectively with an EP1 subtype prostaglandin E2 receptor.
2009-07-03 GO:0050681 androgen receptor binding Deleted DEFINITION Interacting selectively with an androgen receptor.
2009-07-03 GO:0031760 Edg-7 lysophosphatidic acid receptor binding Deleted DEFINITION Interacting selectively with an Edg-7 lysophosphatidic acid receptor.
2009-07-03 GO:0045519 interleukin-23 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-23 receptor.
2009-07-03 GO:0043295 glutathione binding Deleted DEFINITION Interacting selectively with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.
2009-07-03 GO:0033204 ribonuclease P RNA binding Deleted DEFINITION Interacting selectively with the RNA subunit of ribonuclease P.
2009-07-03 GO:0043395 heparan sulfate proteoglycan binding Deleted DEFINITION Interacting selectively with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
2009-07-03 GO:0031702 type 1 angiotensin receptor binding Deleted DEFINITION Interacting selectively with a type 1 angiotensin receptor.
2009-07-03 GO:0070644 vitamin D response element binding Deleted DEFINITION Interacting selectively with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
2009-07-03 GO:0033613 activating transcription factor binding Deleted DEFINITION Interacting selectively with a transcription activator, any protein whose activity is required to initiate or upregulate transcription.
2009-07-03 GO:0015643 toxic substance binding Deleted DEFINITION Interacting selectively with a toxin, a poisonous substance that causes damage to biological systems. Toxins are differentiated from simple chemical poisons and vegetable alkaloids by their high molecular weight and antigenicity (they elicit an antibody response).
2009-07-03 GO:0042162 telomeric DNA binding Deleted DEFINITION Interacting selectively with telomere-associated DNA, usually characterized by highly repetitive sequences.
2009-07-03 GO:0043522 leucine zipper domain binding Deleted DEFINITION Interacting selectively with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns.
2009-07-03 GO:0030629 U6 snRNA 3'-end binding Deleted DEFINITION Interacting selectively with the 3' end of the U6 small nuclear RNA (U6 snRNA).
2009-07-03 GO:0001851 complement component C3b binding Deleted DEFINITION Interacting selectively with the C3b product of the complement cascade.
2009-07-03 GO:0031773 kisspeptin receptor binding Deleted DEFINITION Interacting selectively with a kisspeptin receptor.
2009-07-03 GO:0048495 Roundabout binding Deleted DEFINITION Interacting selectively with the Roundabout (ROBO) receptor, a transmembrane receptor.
2009-07-03 GO:0005110 frizzled-2 binding Deleted DEFINITION Interacting selectively with frizzled-2 (fz2).
2009-07-03 GO:0005536 glucose binding Deleted DEFINITION Interacting selectively with the D- or L-enantiomer of glucose.
2009-07-03 GO:0002061 pyrimidine nucleobase binding Deleted DEFINITION Interacting selectively with a pyrimidine, an organic nitrogenous base.
2009-07-03 GO:0051861 glycolipid binding Deleted DEFINITION Interacting selectively with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.
2009-07-03 GO:0031840 type 2 neuromedin U receptor binding Deleted DEFINITION Interacting selectively with a type 2 neuromedin U receptor.
2009-07-03 GO:0042379 chemokine receptor binding Deleted DEFINITION Interacting selectively with any chemokine receptor.
2009-07-03 GO:0045517 interleukin-20 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-20 receptor.
2009-07-03 GO:0045569 TRAIL binding Deleted DEFINITION Interacting selectively with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.
2009-07-03 GO:0001856 complement component C5a binding Deleted DEFINITION Interacting selectively with the C5a product of the complement cascade.
2009-07-03 GO:0001862 collectin binding Deleted DEFINITION Interacting selectively with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.
2009-07-03 GO:0008035 high-density lipoprotein particle binding Deleted DEFINITION Interacting selectively with high-density lipoprotein: one of the classes of lipoproteins found in blood plasma in many animals (data normally relate to humans).
2009-07-03 GO:0016169 bacteriochlorophyll c binding Deleted DEFINITION Interacting selectively with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.
2009-07-03 GO:0051787 misfolded protein binding Deleted DEFINITION Interacting selectively with a misfolded protein.
2009-07-03 GO:0000149 SNARE binding Deleted DEFINITION Interacting selectively with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
2009-07-03 GO:0051530 NFAT5 protein binding Deleted DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a member of the NFAT transcription factor family which is not calcium regulated.
2009-07-03 GO:0045504 dynein heavy chain binding Deleted DEFINITION Interacting selectively with a heavy chain of the dynein complex.
2009-07-03 GO:0017137 Rab GTPase binding Deleted DEFINITION Interacting selectively with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
2009-07-03 GO:0005146 leukemia inhibitory factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the leukemia inhibitory factor receptor.
2009-07-03 GO:0070300 phosphatidic acid binding Deleted DEFINITION Interacting selectively with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
2009-07-03 GO:0032794 GTPase activating protein binding Deleted DEFINITION Interacting selectively with a GTPase activating protein.
2009-07-03 GO:0000498 base pairing with RNA Deleted DEFINITION Interacting selectively with ribonucleic acid (RNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target RNA molecule.
2009-07-03 GO:0032564 dATP binding Deleted DEFINITION Interacting selectively with dATP, deoxyadenosine triphosphate.
2009-07-03 GO:0042835 BRE binding Deleted DEFINITION Interacting selectively with the RNA element BRE (Bruno response element).
2009-07-03 GO:0005497 androgen binding Added DEFINITION Interacting selectively and non-covalently with any androgen, male sex hormones.
2009-07-03 GO:0005507 copper ion binding Added DEFINITION Interacting selectively and non-covalently with copper (Cu) ions.
2009-07-03 GO:0005518 collagen binding Added DEFINITION Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2009-07-03 GO:0005521 lamin binding Added DEFINITION Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
2009-07-03 GO:0005524 ATP binding Added DEFINITION Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2009-07-03 GO:0005549 odorant binding Added DEFINITION Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell.
2009-07-03 GO:0005550 pheromone binding Added DEFINITION Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
2009-07-03 GO:0008022 protein C-terminus binding Added DEFINITION Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2009-07-03 GO:0008144 drug binding Added DEFINITION Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2009-07-03 GO:0008198 ferrous iron binding Added DEFINITION Interacting selectively and non-covalently with ferrous iron, Fe(II).
2009-07-03 GO:0008431 vitamin E binding Added DEFINITION Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
2009-07-03 GO:0010314 phosphatidylinositol-5-phosphate binding Added DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a phosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0010843 promoter binding Added DEFINITION Interacting selectively and non-covalently within the regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery.
2009-07-03 GO:0010844 recombination hotspot binding Added DEFINITION Interacting selectively and non-covalently with a region in a genome which promotes recombination.
2009-07-03 GO:0016936 galactoside binding Added DEFINITION Interacting selectively and non-covalently with any glycoside in which the sugar moiety is galactose.
2009-07-03 GO:0017022 myosin binding Added DEFINITION Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
2009-07-03 GO:0017046 peptide hormone binding Added DEFINITION Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
2009-07-03 GO:0017049 GTP-Rho binding Added DEFINITION Interacting selectively and non-covalently with the GTP-bound form of the Rho protein.
2009-07-03 GO:0017058 FH1 domain binding Added DEFINITION Interacting selectively and non-covalently with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.
2009-07-03 GO:0019826 oxygen sensor activity Added DEFINITION Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).
2009-07-03 GO:0019862 IgA binding Added DEFINITION Interacting selectively and non-covalently with an immunoglobulin of an IgA isotype.
2009-07-03 GO:0019902 phosphatase binding Added DEFINITION Interacting selectively and non-covalently with any phosphatase.
2009-07-03 GO:0019956 chemokine binding Added DEFINITION Interacting selectively and non-covalently with a chemokine, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions.
2009-07-03 GO:0019964 interferon-gamma binding Added DEFINITION Interacting selectively and non-covalently with interferon-gamma. Interferon-gamma is also known as type II interferon.
2009-07-03 GO:0019978 interleukin-3 binding Added DEFINITION Interacting selectively and non-covalently with interleukin-3.
2009-07-03 GO:0019980 interleukin-5 binding Added DEFINITION Interacting selectively and non-covalently with interleukin-5.
2009-07-03 GO:0030215 semaphorin receptor binding Added DEFINITION Interacting selectively and non-covalently with semaphorin receptors.
2009-07-03 GO:0030306 ADP-ribosylation factor binding Added DEFINITION Interacting selectively and non-covalently with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells.
2009-07-03 GO:0030331 estrogen receptor binding Added DEFINITION Interacting selectively and non-covalently with an estrogen receptor.
2009-07-03 GO:0030348 syntaxin-3 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-3.
2009-07-03 GO:0030370 intercellular adhesion molecule-3 receptor binding Added DEFINITION Interacting selectively and non-covalently with receptors for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1.
2009-07-03 GO:0030911 TPR domain binding Added DEFINITION Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.
2009-07-03 GO:0030984 kininogen binding Added DEFINITION Interacting selectively and non-covalently with a kininogen, any of a group of plasma proteins that are kinin precursors.
2009-07-03 GO:0030986 low molecular weight kininogen binding Added DEFINITION Interacting selectively and non-covalently with a kininogen of low molecular mass.
2009-07-03 GO:0031005 filamin binding Added DEFINITION Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.
2009-07-03 GO:0031418 L-ascorbic acid binding Added DEFINITION Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
2009-07-03 GO:0031493 nucleosomal histone binding Added DEFINITION Interacting selectively and non-covalently with a histone that is assembled into a nucleosome.
2009-07-03 GO:0031593 polyubiquitin binding Added DEFINITION Interacting selectively and non-covalently and non-covalently with a polymer of ubiqutin.
2009-07-03 GO:0031682 G-protein gamma-subunit binding Added DEFINITION Interacting selectively and non-covalently with a G-protein gamma subunit.
2009-07-03 GO:0031691 alpha-1A adrenergic receptor binding Added DEFINITION Interacting selectively and non-covalently with an alpha-1A adrenergic receptor.
2009-07-03 GO:0031695 alpha-2B adrenergic receptor binding Added DEFINITION Interacting selectively and non-covalently with an alpha-2B adrenergic receptor.
2009-07-03 GO:0031700 adrenomedullin receptor binding Added DEFINITION Interacting selectively and non-covalently with an adrenomedullin receptor.
2009-07-03 GO:0031712 B1 bradykinin receptor binding Added DEFINITION Interacting selectively and non-covalently with a B1 bradykinin receptor.
2009-07-03 GO:0031717 cannabinoid receptor binding Added DEFINITION Interacting selectively and non-covalently with a cannabinoid receptor.
2009-07-03 GO:0031726 CCR1 chemokine receptor binding Added DEFINITION Interacting selectively and non-covalently with a CCR1 chemokine receptor.
2009-07-03 GO:0031741 type B gastrin/cholecystokinin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type B gastrin/cholecystokinin receptor.
2009-07-03 GO:0031752 D5 dopamine receptor binding Added DEFINITION Interacting selectively and non-covalently with a D5 dopamine receptor.
2009-07-03 GO:0031757 Edg-4 lysophosphatidic acid receptor binding Added DEFINITION Interacting selectively and non-covalently with an Edg-4 lysophosphatidic acid receptor.
2009-07-03 GO:0031766 type 3 galanin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 3 galanin receptor.
2009-07-03 GO:0031781 type 3 melanocortin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 3 melanocortin receptor.
2009-07-03 GO:0031783 type 5 melanocortin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 5 melanocortin receptor.
2009-07-03 GO:0031784 melatonin receptor binding Added DEFINITION Interacting selectively and non-covalently with a melatonin receptor.
2009-07-03 GO:0031799 type 2 metabotropic glutamate receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 2 metabotropic glutamate receptor.
2009-07-03 GO:0031804 type 7 metabotropic glutamate receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 7 metabotropic glutamate receptor.
2009-07-03 GO:0031828 type 2C serotonin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 2C serotonin receptor.
2009-07-03 GO:0031861 prolactin-releasing peptide receptor binding Added DEFINITION Interacting selectively and non-covalently with a prolactin-releasing peptide receptor.
2009-07-03 GO:0031864 EP1 subtype prostaglandin E2 receptor binding Added DEFINITION Interacting selectively and non-covalently with an EP1 subtype prostaglandin E2 receptor.
2009-07-03 GO:0031870 thromboxane A2 receptor binding Added DEFINITION Interacting selectively and non-covalently with a thromboxane A2 receptor.
2009-07-03 GO:0031884 type 1 member 1 taste receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 1 member 1 taste receptor.
2009-07-03 GO:0051525 NFAT protein binding Deleted DEFINITION Interacting selectively with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
2009-07-03 GO:0002020 protease binding Deleted DEFINITION Interacting selectively with any protease or peptidase.
2009-07-03 GO:0034189 very-low-density lipoprotein particle binding Deleted DEFINITION Interacting selectively with very-low-density lipoprotein, one of the classes of lipoproteins found in blood plasma in many animals.
2009-07-03 GO:0005540 hyaluronic acid binding Deleted DEFINITION Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
2009-07-03 GO:0000822 inositol hexakisphosphate binding Deleted DEFINITION Interacting selectively with inositol hexakisphosphate.
2009-07-03 GO:0005509 calcium ion binding Deleted DEFINITION Interacting selectively with calcium ions (Ca2+).
2009-07-03 GO:0051419 nebulin binding Deleted DEFINITION Interacting selectively with nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone.
2009-07-03 GO:0017033 DNA topoisomerase I binding Deleted DEFINITION Interacting selectively with the enzyme DNA topoisomerase I.
2009-07-03 GO:0032795 heterotrimeric G-protein binding Deleted DEFINITION Interacting selectively with a heterotrimeric G-protein.
2009-07-03 GO:0051393 alpha-actinin binding Deleted DEFINITION Interacting selectively with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
2009-07-03 GO:0005524 ATP binding Deleted DEFINITION Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2009-07-03 GO:0051526 NFAT1 protein binding Deleted DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a calcium-regulated protein which acts as a transcription factor.
2009-07-03 GO:0030941 chloroplast targeting sequence binding Deleted DEFINITION Interacting selectively with a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast.
2009-07-03 GO:0017069 snRNA binding Deleted DEFINITION Interacting selectively with a small nuclear RNA (snRNA).
2009-07-03 GO:0051430 corticotropin-releasing hormone receptor 1 binding Deleted DEFINITION Interacting selectively with the protein corticotropin-releasing hormone receptor 1 (CRHR1). The CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on adrenocorticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.
2009-07-03 GO:0031857 type 1 parathyroid hormone receptor binding Deleted DEFINITION Interacting selectively with a type 1 parathyroid hormone receptor.
2009-07-03 GO:0031875 type 4 proteinase activated receptor binding Deleted DEFINITION Interacting selectively with a type 4 proteinase activated receptor.
2009-07-03 GO:0051435 BH4 domain binding Deleted DEFINITION Interacting selectively with the BH4 domain of a protein of the Bcl-2 family. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.
2009-07-03 GO:0050811 GABA receptor binding Deleted DEFINITION Interacting selectively with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
2009-07-03 GO:0032136 adenine/cytosine mispair binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing an A/C mispair.
2009-07-03 GO:0032408 MutSbeta complex binding Deleted DEFINITION Interacting selectively with the mismatch repair complex MutSbeta.
2009-07-03 GO:0019981 interleukin-6 binding Deleted DEFINITION Interacting selectively with interleukin-6.
2009-07-03 GO:0031762 follicle-stimulating hormone receptor binding Deleted DEFINITION Interacting selectively with a follicle stimulating hormone receptor.
2009-07-03 GO:0030883 endogenous lipid antigen binding Deleted DEFINITION Interacting selectively with an endogenous cellular lipid antigen.
2009-07-03 GO:0030348 syntaxin-3 binding Deleted DEFINITION Interacting selectively with the SNAP receptor syntaxin-3.
2009-07-03 GO:0032548 pyrimidine deoxyribonucleoside binding Deleted DEFINITION Interacting selectively with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.
2009-07-03 GO:0005133 interferon-gamma receptor binding Deleted DEFINITION Interacting selectively with the interferon-gamma receptor.
2009-07-03 GO:0031784 melatonin receptor binding Deleted DEFINITION Interacting selectively with a melatonin receptor.
2009-07-03 GO:0032137 guanine/thymine mispair binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing a G/T mispair.
2009-07-03 GO:0031876 secretin receptor binding Deleted DEFINITION Interacting selectively with a secretin receptor.
2009-07-03 GO:0043515 kinetochore binding Deleted DEFINITION Interacting selectively with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.
2009-07-03 GO:0032028 myosin head/neck binding Deleted DEFINITION Interacting selectively with the head/neck region of a myosin heavy chain.
2009-07-03 GO:0032031 myosin I head/neck binding Deleted DEFINITION Interacting selectively with the head/neck region of a myosin I heavy chain.
2009-07-03 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Deleted DEFINITION Interacting selectively with the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein.
2009-07-03 GO:0031721 hemoglobin alpha binding Deleted DEFINITION Interacting selectively with a hemoglobin alpha chain.
2009-07-03 GO:0031764 type 1 galanin receptor binding Deleted DEFINITION Interacting selectively with a type 1 galanin receptor.
2009-07-03 GO:0032181 dinucleotide repeat insertion binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.
2009-07-03 GO:0032143 single thymine insertion binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine.
2009-07-03 GO:0031782 type 4 melanocortin receptor binding Deleted DEFINITION Interacting selectively with a type 4 melanocortin receptor.
2009-07-03 GO:0050824 water binding Deleted DEFINITION Interacting selectively with water (H2O).
2009-07-03 GO:0019841 retinol binding Deleted DEFINITION Interacting selectively with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
2009-07-03 GO:0031765 type 2 galanin receptor binding Deleted DEFINITION Interacting selectively with a type 2 galanin receptor.
2009-07-03 GO:0045521 interleukin-25 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-25 receptor.
2009-07-03 GO:0042021 granulocyte macrophage colony-stimulating factor complex binding Deleted DEFINITION Interacting selectively with the granulocyte macrophage colony-stimulating factor complex.
2009-07-03 GO:0070051 fibrinogen binding Deleted DEFINITION Interacting selectively with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.
2009-07-03 GO:0031882 type 5 somatostatin receptor binding Deleted DEFINITION Interacting selectively with a type 5 somatostatin receptor.
2009-07-03 GO:0043120 tumor necrosis factor binding Deleted DEFINITION Interacting selectively with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.
2009-07-03 GO:0031819 P2Y10 nucleotide receptor binding Deleted DEFINITION Interacting selectively with a P2Y10 nucleotide receptor.
2009-07-03 GO:0005119 smoothened binding Deleted DEFINITION Interacting selectively with the smoothened (smo) protein, which interacts with patched to transmit hedgehog signals.
2009-07-03 GO:0032406 MutLbeta complex binding Deleted DEFINITION Interacting selectively with the mismatch repair complex MutLbeta.
2009-07-03 GO:0035254 glutamate receptor binding Deleted DEFINITION Interacting selectively with a glutamate receptor.
2009-07-03 GO:0042657 MHC class II protein binding, via lateral surface Deleted DEFINITION Interacting selectively with the lateral surface of major histocompatibility complex class II molecules.
2009-07-03 GO:0005529 sugar binding Deleted DEFINITION Interacting selectively with any mono-, di- or trisaccharide carbohydrate.
2009-07-03 GO:0031874 type 3 proteinase activated receptor binding Deleted DEFINITION Interacting selectively with a type 3 proteinase activated receptor.
2009-07-03 GO:0005519 cytoskeletal regulatory protein binding Deleted DEFINITION Interacting selectively with any protein involved in modulating the reorganization of the cytoskeleton.
2009-07-03 GO:0031738 XCR1 chemokine receptor binding Deleted DEFINITION Interacting selectively with a XCR1 chemokine receptor.
2009-07-03 GO:0030975 thiamine binding Deleted DEFINITION Interacting selectively with thiamin (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
2009-07-03 GO:0005046 KDEL sequence binding Deleted DEFINITION Interacting selectively with a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
2009-07-03 GO:0031885 type 1 member 2 taste receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 1 member 2 taste receptor.
2009-07-03 GO:0031961 cortisol receptor binding Added DEFINITION Interacting selectively and non-covalently with a cortisol receptor.
2009-07-03 GO:0031996 thioesterase binding Added DEFINITION Interacting selectively and non-covalently with any thioesterase enzyme.
2009-07-03 GO:0031997 N-terminal myristoylation domain binding Added DEFINITION Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.
2009-07-03 GO:0032028 myosin head/neck binding Added DEFINITION Interacting selectively and non-covalently with the head/neck region of a myosin heavy chain.
2009-07-03 GO:0032037 myosin I heavy chain binding Added DEFINITION Interacting selectively and non-covalently with a heavy chain of a myosin I complex.
2009-07-03 GO:0005149 interleukin-1 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-1 receptor.
2009-07-03 GO:0005161 platelet-derived growth factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
2009-07-03 GO:0005170 neurotrophin TRKC receptor binding Added DEFINITION Interacting selectively and non-covalently with the neurotrophin TRKC receptor.
2009-07-03 GO:0005483 soluble NSF attachment protein activity Added DEFINITION Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.
2009-07-03 GO:0005496 steroid binding Added DEFINITION Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
2009-07-03 GO:0051015 actin filament binding Deleted DEFINITION Interacting selectively with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2009-07-03 GO:0043274 phospholipase binding Deleted DEFINITION Interacting selectively with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.
2009-07-03 GO:0043184 vascular endothelial growth factor receptor 2 binding Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2009-07-03 GO:0031878 type 1 somatostatin receptor binding Deleted DEFINITION Interacting selectively with a type 1 somatostatin receptor.
2009-07-03 GO:0032038 myosin II heavy chain binding Deleted DEFINITION Interacting selectively with a heavy chain of a myosin II complex.
2009-07-03 GO:0051378 serotonin binding Deleted DEFINITION Interacting selectively with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
2009-07-03 GO:0043130 ubiquitin binding Deleted DEFINITION Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
2009-07-03 GO:0031788 motilin receptor binding Deleted DEFINITION Interacting selectively with a motilin receptor.
2009-07-03 GO:0031801 type 4 metabotropic glutamate receptor binding Deleted DEFINITION Interacting selectively with a type 4 metabotropic glutamate receptor.
2009-07-03 GO:0019864 IgG binding Deleted DEFINITION Interacting selectively with an immunoglobulin of an IgG isotype.
2009-07-03 GO:0001968 fibronectin binding Deleted DEFINITION Interacting selectively with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
2009-07-03 GO:0050544 arachidonic acid binding Deleted DEFINITION Interacting selectively with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
2009-07-03 GO:0031722 hemoglobin beta binding Deleted DEFINITION Interacting selectively with a hemoglobin beta chain.
2009-07-03 GO:0032137 guanine/thymine mispair binding Added DEFINITION Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair.
2009-07-03 GO:0032403 protein complex binding Added DEFINITION Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2009-07-03 GO:0032422 purine-rich negative regulatory element binding Added DEFINITION Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
2009-07-03 GO:0032448 DNA hairpin binding Added DEFINITION Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.
2009-07-03 GO:0032547 purine deoxyribonucleoside binding Added DEFINITION Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.
2009-07-03 GO:0032552 deoxyribonucleotide binding Added DEFINITION Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
2009-07-03 GO:0032561 guanyl ribonucleotide binding Added DEFINITION Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
2009-07-03 GO:0033149 FFAT motif binding Added DEFINITION Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.
2009-07-03 GO:0033204 ribonuclease P RNA binding Added DEFINITION Interacting selectively and non-covalently with the RNA subunit of ribonuclease P.
2009-07-03 GO:0033219 urea binding Added DEFINITION Interacting selectively and non-covalently with urea, a water-soluble carboxamide with the structure H2N-CO-NH2.
2009-07-03 GO:0034187 apolipoprotein E binding Added DEFINITION Interacting selectively and non-covalently with apolipoprotein E.
2009-07-03 GO:0034237 protein kinase A regulatory subunit binding Added DEFINITION Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.
2009-07-03 GO:0034347 type III interferon binding Added DEFINITION Interacting selectively and non-covalently with a type III interferon. Type III interferons are members of the interferon-lambda gene family.
2009-07-03 GO:0034513 box H/ACA snoRNA binding Added DEFINITION Interacting selectively and non-covalently with box H/ACA small nucleolar RNA.
2009-07-03 GO:0034988 Fc-gamma receptor I complex binding Added DEFINITION Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.
2009-07-03 GO:0035240 dopamine binding Added DEFINITION Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.
2009-07-03 GO:0035257 nuclear hormone receptor binding Added DEFINITION Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.
2009-07-03 GO:0042287 MHC protein binding Added DEFINITION Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
2009-07-03 GO:0042393 histone binding Added DEFINITION Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2009-07-03 GO:0042605 peptide antigen binding Added DEFINITION Interacting selectively and non-covalently with an antigen peptide, a fragment of a foreign protein derived by proteolysis within the cell.
2009-07-03 GO:0042658 MHC class II protein binding, via antigen binding groove Added DEFINITION Interacting selectively and non-covalently with the antigen binding groove of major histocompatibility complex class II molecules.
2009-07-03 GO:0042834 peptidoglycan binding Added DEFINITION Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
2009-07-03 GO:0043022 ribosome binding Added DEFINITION Interacting selectively and non-covalently with any part of a ribosome.
2009-07-03 GO:0043024 ribosomal small subunit binding Added DEFINITION Interacting selectively and non-covalently with any part of the small ribosomal subunit.
2009-07-03 GO:0043035 chromatin insulator sequence binding Added DEFINITION Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
2009-07-03 GO:0043169 cation binding Added DEFINITION Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
2009-07-03 GO:0043178 alcohol binding Added DEFINITION Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group.
2009-07-03 GO:0043208 glycosphingolipid binding Added DEFINITION Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
2009-07-03 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding Added DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a diphosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0043498 cell surface binding Added DEFINITION Interacting selectively and non-covalently with any component on the surface of a cell.
2009-07-03 GO:0045015 HDEL sequence binding Added DEFINITION Interacting selectively and non-covalently with a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
2009-07-03 GO:0045159 myosin II binding Added DEFINITION Interacting selectively and non-covalently with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.
2009-07-03 GO:0045322 unmethylated CpG binding Added DEFINITION Interacting selectively and non-covalently with unmethylated CpG motifs. Unmethylated CpG dinucleotides are often associated with gene promoters.
2009-07-03 GO:0045502 dynein binding Added DEFINITION Interacting selectively and non-covalently with dynein, the multisubunit protein complex that is associated with microtubules.
2009-07-03 GO:0045521 interleukin-25 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-25 receptor.
2009-07-03 GO:0045522 interleukin-26 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-26 receptor.
2009-07-03 GO:0046980 tapasin binding Added DEFINITION Interacting selectively and non-covalently with tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules.
2009-07-03 GO:0048185 activin binding Added DEFINITION Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits.
2009-07-03 GO:0048273 mitogen-activated protein kinase p38 binding Added DEFINITION Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.
2009-07-03 GO:0048495 Roundabout binding Added DEFINITION Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.
2009-07-03 GO:0048602 fibroblast growth factor 1 binding Added DEFINITION Interacting selectively and non-covalently with fibroblast growth factor 1.
2009-07-03 GO:0050430 syntaxin-6 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-6.
2009-07-03 GO:0050543 icosatetraenoic acid binding Added DEFINITION Interacting selectively and non-covalently with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.
2009-07-03 GO:0050693 LBD domain binding Added DEFINITION Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.
2009-07-03 GO:0032399 HECT domain binding Deleted DEFINITION Interacting selectively with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein.
2009-07-03 GO:0003786 actin lateral binding Deleted DEFINITION Interacting selectively with an actin filament along its length.
2009-07-03 GO:0043560 insulin receptor substrate binding Deleted DEFINITION Interacting selectively with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.
2009-07-03 GO:0001884 pyrimidine nucleoside binding Deleted DEFINITION Interacting selectively with a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose.
2009-07-03 GO:0035259 glucocorticoid receptor binding Deleted DEFINITION Interacting selectively with a glucocorticoid receptor.
2009-07-03 GO:0002039 p53 binding Deleted DEFINITION Interacting selectively with one of the p53 family of proteins.
2009-07-03 GO:0043495 protein anchor Deleted DEFINITION Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2009-07-03 GO:0034712 inhibin alpha binding Deleted DEFINITION Interacting selectively with inhibin alpha.
2009-07-03 GO:0016597 amino acid binding Deleted DEFINITION Interacting selectively with an amino acid, organic acids containing one or more amino substituents.
2009-07-03 GO:0051434 BH3 domain binding Deleted DEFINITION Interacting selectively with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.
2009-07-03 GO:0031749 D2 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D2 dopamine receptor.
2009-07-03 GO:0031863 prostaglandin D2 receptor binding Deleted DEFINITION Interacting selectively with a prostaglandin D2 receptor.
2009-07-03 GO:0008289 lipid binding Deleted DEFINITION Interacting selectively with a lipid.
2009-07-03 GO:0032403 protein complex binding Deleted DEFINITION Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2009-07-03 GO:0031846 neurotensin receptor binding Deleted DEFINITION Interacting selectively with a neurotensin receptor.
2009-07-03 GO:0051381 histamine binding Deleted DEFINITION Interacting selectively with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
2009-07-03 GO:0048607 fibroblast growth factor 6 binding Deleted DEFINITION Interacting selectively with fibroblast growth factor 6.
2009-07-03 GO:0005518 collagen binding Deleted DEFINITION Interacting selectively with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2009-07-03 GO:0031786 type 1B melatonin receptor binding Deleted DEFINITION Interacting selectively with a type 1B melatonin receptor.
2009-07-03 GO:0032145 succinate-semialdehyde dehydrogenase binding Deleted DEFINITION Interacting selectively with succinate-semialdehyde dehydrogenase.
2009-07-03 GO:0042019 interleukin-23 binding Deleted DEFINITION Interacting selectively with interleukin-23.
2009-07-03 GO:0005534 galactose binding Deleted DEFINITION Interacting selectively with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.
2009-07-03 GO:0030973 molybdate ion binding Deleted DEFINITION Interacting selectively with molybdate (MoO4 2-) ions.
2009-07-03 GO:0003785 actin monomer binding Deleted DEFINITION Interacting selectively with monomeric actin, also known as G-actin.
2009-07-03 GO:0000049 tRNA binding Deleted DEFINITION Interacting selectively with transfer RNA.
2009-07-03 GO:0048603 fibroblast growth factor 2 binding Deleted DEFINITION Interacting selectively with fibroblast growth factor 2.
2009-07-03 GO:0035198 miRNA binding Deleted DEFINITION Interacting selectively with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
2009-07-03 GO:0008134 transcription factor binding Deleted DEFINITION Interacting selectively with a transcription factor, any protein required to initiate or regulate transcription.
2009-07-03 GO:0000340 RNA 7-methylguanosine cap binding Deleted DEFINITION Interacting selectively with the 7-methylguanosine moiety added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.
2009-07-03 GO:0030619 U1 snRNA binding Deleted DEFINITION Interacting selectively with the U1 small nuclear RNA (U1 snRNA).
2009-07-03 GO:0008262 importin-alpha export receptor activity Deleted DEFINITION Interacting selectively with importin-alpha to mediate its transfer through the nuclear pore to the cytoplasm.
2009-07-03 GO:0045296 cadherin binding Deleted DEFINITION Interacting selectively with cadherin, a type I membrane protein involved in cell adhesion.
2009-07-03 GO:0030156 benzodiazepine receptor binding Deleted DEFINITION Interacting selectively with the peripheral benzodiazepine receptor (PBR).
2009-07-03 GO:0031852 mu-type opioid receptor binding Deleted DEFINITION Interacting selectively with a mu-type opioid receptor.
2009-07-03 GO:0005123 death receptor binding Deleted DEFINITION Interacting selectively with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).
2009-07-03 GO:0051370 ZASP binding Deleted DEFINITION Interacting selectively with Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain.
2009-07-03 GO:0031745 cysteinyl leukotriene receptor binding Deleted DEFINITION Interacting selectively with a cysteinyl leukotriene receptor.
2009-07-03 GO:0008317 gurken receptor binding Deleted DEFINITION Interacting selectively with the gurken growth factor receptor.
2009-07-03 GO:0033130 acetylcholine receptor binding Deleted DEFINITION Interacting selectively with an acetylcholine receptor.
2009-07-03 GO:0017129 triglyceride binding Deleted DEFINITION Interacting selectively with any triester of glycerol.
2009-07-03 GO:0070653 high-density lipoprotein particle receptor binding Deleted DEFINITION Interacting selectively with a high-density lipoprotein receptor.
2009-07-03 GO:0032555 purine ribonucleotide binding Deleted DEFINITION Interacting selectively with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
2009-07-03 GO:0005523 tropomyosin binding Deleted DEFINITION Interacting selectively with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.
2009-07-03 GO:0030544 Hsp70 protein binding Deleted DEFINITION Interacting selectively with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
2009-07-03 GO:0048028 galacturonan binding Deleted DEFINITION Interacting selectively with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.
2009-07-03 GO:0005145 interleukin-14 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-14 receptor.
2009-07-03 GO:0050897 cobalt ion binding Deleted DEFINITION Interacting selectively with a cobalt (Co) ion.
2009-07-03 GO:0032266 phosphatidylinositol-3-phosphate binding Deleted DEFINITION Interacting selectively with phosphatidylinositol 3-phosphate, a phosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0031893 vasopressin receptor binding Deleted DEFINITION Interacting selectively with a vasopressin receptor.
2009-07-03 GO:0050699 WW domain binding Added DEFINITION Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
2009-07-03 GO:0050700 CARD domain binding Added DEFINITION Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.
2009-07-03 GO:0050811 GABA receptor binding Added DEFINITION Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
2009-07-03 GO:0050997 quaternary ammonium group binding Added DEFINITION Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
2009-07-03 GO:0051010 microtubule plus-end binding Added DEFINITION Interacting selectively and non-covalently with the plus end of a microtubule.
2009-07-03 GO:0051015 actin filament binding Added DEFINITION Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2009-07-03 GO:0051019 mitogen-activated protein kinase binding Added DEFINITION Interacting selectively and non-covalently with a mitogen-activated protein kinase.
2009-07-03 GO:0051416 myotilin binding Added DEFINITION Interacting selectively and non-covalently with myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C.
2009-07-03 GO:0051433 BH2 domain binding Added DEFINITION Interacting selectively and non-covalently with the BH2 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.
2009-07-03 GO:0051535 syntaxin-5 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-5.
2009-07-03 GO:0051577 MyoD binding Added DEFINITION Interacting selectively and non-covalently with the muscle regulatory factor MyoD.
2009-07-03 GO:0051916 granulocyte colony-stimulating factor binding Added DEFINITION Interacting selectively and non-covalently with granulocyte colony-stimulating factor, G-CSF.
2009-07-03 GO:0051959 dynein light intermediate chain binding Added DEFINITION Interacting selectively and non-covalently with a light intermediate chain of the dynein complex.
2009-07-03 GO:0055100 adiponectin binding Added DEFINITION Interacting selectively and non-covalently with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.
2009-07-03 GO:0070080 titin Z domain binding Added DEFINITION Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
2009-07-03 GO:0001852 complement component iC3b binding Deleted DEFINITION Interacting selectively with the iC3b product of the complement cascade.
2009-07-03 GO:0005522 profilin binding Deleted DEFINITION Interacting selectively with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.
2009-07-03 GO:0030622 U4atac snRNA binding Deleted DEFINITION Interacting selectively with the U4atac small nuclear RNA (U4atac snRNA).
2009-07-03 GO:0017046 peptide hormone binding Deleted DEFINITION Interacting selectively with any peptide with hormonal activity in animals.
2009-07-03 GO:0050839 cell adhesion molecule binding Deleted DEFINITION Interacting selectively with a cell adhesion molecule.
2009-07-03 GO:0034513 box H/ACA snoRNA binding Deleted DEFINITION Interacting selectively with box H/ACA small nucleolar RNA.
2009-07-03 GO:0070539 linoleic acid binding Deleted DEFINITION Interacting selectively with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.
2009-07-03 GO:0003676 nucleic acid binding Deleted DEFINITION Interacting selectively with any nucleic acid.
2009-07-03 GO:0019003 GDP binding Deleted DEFINITION Interacting selectively with GDP, guanosine 5'-diphosphate.
2009-07-03 GO:0051416 myotilin binding Deleted DEFINITION Interacting selectively with myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C.
2009-07-03 GO:0009367 prepilin peptidase complex Deleted DEFINITION An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group.
2009-07-03 GO:0031804 type 7 metabotropic glutamate receptor binding Deleted DEFINITION Interacting selectively with a type 7 metabotropic glutamate receptor.
2009-07-03 GO:0046876 3,4-didehydroretinal binding Deleted DEFINITION Interacting selectively with 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).
2009-07-03 GO:0043014 alpha-tubulin binding Deleted DEFINITION Interacting selectively with the microtubule constituent protein alpha-tubulin.
2009-07-03 GO:0042277 peptide binding Deleted DEFINITION Interacting selectively with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
2009-07-03 GO:0032547 purine deoxyribonucleoside binding Deleted DEFINITION Interacting selectively with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.
2009-07-03 GO:0033149 FFAT motif binding Deleted DEFINITION Interacting selectively with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.
2009-07-03 GO:0000339 RNA cap binding Deleted DEFINITION Interacting selectively with a 7-methylguanosine (m7G) moiety or derivative located at the 5' end of an RNA molecule.
2009-07-03 GO:0051577 MyoD binding Deleted DEFINITION Interacting selectively with the muscle regulatory factor MyoD.
2009-07-03 GO:0005102 receptor binding Deleted DEFINITION Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2009-07-03 GO:0043121 neurotrophin binding Deleted DEFINITION Interacting selectively with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth.
2009-07-03 GO:0031796 type 1 metabotropic GABA receptor binding Deleted DEFINITION Interacting selectively with a type 1 metabotropic GABA receptor.
2009-07-03 GO:0070362 mitochondrial heavy strand promoter anti-sense binding Deleted DEFINITION Interacting selectively with the anti-sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA.
2009-07-03 GO:0017076 purine nucleotide binding Deleted DEFINITION Interacting selectively with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.
2009-07-03 GO:0045523 interleukin-27 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-27 receptor.
2009-07-03 GO:0003682 chromatin binding Deleted DEFINITION Interacting selectively with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase.
2009-07-03 GO:0032051 clathrin light chain binding Deleted DEFINITION Interacting selectively with a clathrin light chain.
2009-07-03 GO:0030553 cGMP binding Deleted DEFINITION Interacting selectively with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
2009-07-03 GO:0043199 sulfate binding Deleted DEFINITION Interacting selectively with sulfate (SO42-), a negatively charged small molecule.
2009-07-03 GO:0032027 myosin light chain binding Deleted DEFINITION Interacting selectively with a light chain of a myosin complex.
2009-07-03 GO:0031491 nucleosome binding Deleted DEFINITION Interacting selectively with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
2009-07-03 GO:0032559 adenyl ribonucleotide binding Deleted DEFINITION Interacting selectively with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
2009-07-03 GO:0048038 quinone binding Deleted DEFINITION Interacting selectively with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
2009-07-03 GO:0031883 taste receptor binding Deleted DEFINITION Interacting selectively with a taste receptor.
2009-07-03 GO:0030984 kininogen binding Deleted DEFINITION Interacting selectively with a kininogen, any of a group of plasma proteins that are kinin precursors.
2009-07-03 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding Deleted DEFINITION Interacting selectively with phosphatidylinositol-4,5-bisphosphate, a diphosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0070324 thyroid hormone binding Added DEFINITION Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
2009-07-03 GO:0070336 flap-structured DNA binding Added DEFINITION Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.
2009-07-03 GO:0070403 NAD+ binding Added DEFINITION Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
2009-07-03 GO:0070405 ammonium ion binding Added DEFINITION Interacting selectively and non-covalently with ammonium ions (NH4+).
2009-07-03 GO:0070644 vitamin D response element binding Added DEFINITION Interacting selectively and non-covalently with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
2009-07-03 GO:0070700 BMP receptor binding Added DEFINITION Interacting selectively and non-covalently with a BMP receptor.
2009-07-03 GO:0070773 protein-N-terminal glutamine amidohydrolase activity Added DEFINITION Catalysis of the deamidation of an N-terminal glutamin residue of a protein.
2009-07-03 GO:0000035 acyl binding Added DEFINITION Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
2009-07-03 GO:0000182 rDNA binding Added DEFINITION Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA.
2009-07-03 GO:0000287 magnesium ion binding Added DEFINITION Interacting selectively and non-covalently with magnesium (Mg) ions.
2009-07-03 GO:0000341 RNA trimethylguanosine cap binding Added DEFINITION Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) moiety located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.
2009-07-03 GO:0000400 four-way junction DNA binding Added DEFINITION Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
2009-07-03 GO:0000496 base pairing Added DEFINITION Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target nucleic acid molecule.
2009-07-03 GO:0001530 lipopolysaccharide binding Added DEFINITION Interacting selectively and non-covalently with lipopolysaccharide.
2009-07-03 GO:0001531 interleukin-21 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-21 receptor.
2009-07-03 GO:0001540 beta-amyloid binding Added DEFINITION Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor.
2009-07-03 GO:0001664 G-protein coupled receptor binding Added DEFINITION Interacting selectively and non-covalently with a G-protein-coupled receptor.
2009-07-03 GO:0001854 complement component C3d binding Added DEFINITION Interacting selectively and non-covalently with the C3d product of the complement cascade.
2009-07-03 GO:0001871 pattern binding Added DEFINITION Interacting selectively and non-covalently with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan.
2009-07-03 GO:0001872 (1->3)-beta-D-glucan binding Added DEFINITION Interacting selectively and non-covalently with zymosan.
2009-07-03 GO:0001972 retinoic acid binding Added DEFINITION Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
2009-07-03 GO:0002046 opsin binding Added DEFINITION Interacting selectively and non-covalently with an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
2009-07-03 GO:0002112 interleukin-33 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-33 receptor.
2009-07-03 GO:0003691 double-stranded telomeric DNA binding Added DEFINITION Interacting selectively and non-covalently with double-stranded telomere-associated DNA.
2009-07-03 GO:0003692 left-handed Z-DNA binding Added DEFINITION Interacting selectively and non-covalently with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.
2009-07-03 GO:0003695 random coil DNA binding Added DEFINITION Interacting selectively and non-covalently with DNA in a random coil configuration.
2009-07-03 GO:0003723 RNA binding Added DEFINITION Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2009-07-03 GO:0003779 actin binding Added DEFINITION Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2009-07-03 GO:0003823 antigen binding Added DEFINITION Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2009-07-03 GO:0005122 torso binding Added DEFINITION Interacting selectively and non-covalently with the torso (tor) protein, a receptor tyrosine kinase.
2009-07-03 GO:0005134 interleukin-2 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-2 receptor.
2009-07-03 GO:0005147 oncostatin-M receptor binding Added DEFINITION Interacting selectively and non-covalently with the oncostatin-M receptor.
2009-07-03 GO:0005154 epidermal growth factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the epidermal growth factor receptor.
2009-07-03 GO:0019960 C-X3-C chemokine binding Deleted DEFINITION Interacting selectively with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.
2009-07-03 GO:0032546 deoxyribonucleoside binding Deleted DEFINITION Interacting selectively with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.
2009-07-03 GO:0031774 leukotriene receptor binding Added DEFINITION Interacting selectively and non-covalently with a leukotriene receptor.
2009-07-03 GO:0031775 lutropin-choriogonadotropic hormone receptor binding Added DEFINITION Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor.
2009-07-03 GO:0010736 serum response element binding Deleted DEFINITION Interacting selectively with the serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
2009-07-03 GO:0042498 diacyl lipopeptide binding Deleted DEFINITION Interacting selectively with any conjugated, water-soluble protein in which the nonprotein moiety consists of a two acyl groups.
2009-07-03 GO:0005142 interleukin-11 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-11 receptor.
2009-07-03 GO:0034988 Fc-gamma receptor I complex binding Deleted DEFINITION Interacting selectively with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.
2009-07-03 GO:0031754 Edg-1 sphingosine 1-phosphate receptor binding Deleted DEFINITION Interacting selectively with an Edg-1 sphingosine 1-phosphate receptor.
2009-07-03 GO:0031891 type 1 vasoactive intestinal polypeptide receptor binding Deleted DEFINITION Interacting selectively with a type 1 vasoactive intestinal polypeptide receptor.
2009-07-03 GO:0032032 myosin I tail binding Deleted DEFINITION Interacting selectively with the tail region of a myosin I heavy chain.
2009-07-03 GO:0030942 endoplasmic reticulum signal peptide binding Deleted DEFINITION Interacting selectively with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum.
2009-07-03 GO:0030977 taurine binding Deleted DEFINITION Interacting selectively with taurine.
2009-07-03 GO:0032034 myosin II head/neck binding Deleted DEFINITION Interacting selectively with the head/neck region of a myosin II heavy chain.
2009-07-03 GO:0005109 frizzled binding Deleted DEFINITION Interacting selectively with the frizzled (fz) receptor.
2009-07-03 GO:0032405 MutLalpha complex binding Deleted DEFINITION Interacting selectively with the mismatch repair complex MutLalpha.
2009-07-03 GO:0030172 troponin C binding Deleted DEFINITION Interacting selectively with troponin C, the calcium-binding subunit of the troponin complex.
2009-07-03 GO:0031752 D5 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D5 dopamine receptor.
2009-07-03 GO:0043183 vascular endothelial growth factor receptor 1 binding Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 1.
2009-07-03 GO:0070180 large ribosomal subunit rRNA binding Deleted DEFINITION Interacting selectively with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
2009-07-03 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding Deleted DEFINITION Interacting selectively with phosphatidylinositol-3,4-bisphosphate, a diphosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0070080 titin Z domain binding Deleted DEFINITION Interacting selectively with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
2009-07-03 GO:0005070 SH3/SH2 adaptor activity Deleted DEFINITION Interacting selectively and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
2009-07-03 GO:0050998 nitric-oxide synthase binding Deleted DEFINITION Interacting selectively with the enzyme nitric-oxide synthase.
2009-07-03 GO:0008312 7S RNA binding Deleted DEFINITION Interacting selectively with 7S RNA, the RNA component of the signal recognition particle (SRP).
2009-07-03 GO:0031881 type 4 somatostatin receptor binding Deleted DEFINITION Interacting selectively with a type 4 somatostatin receptor.
2009-07-03 GO:0005497 androgen binding Deleted DEFINITION Interacting selectively with any androgen, male sex hormones.
2009-07-03 GO:0031402 sodium ion binding Deleted DEFINITION Interacting selectively with sodium ions (Na+).
2009-07-03 GO:0005171 hepatocyte growth factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the hepatocyte growth factor receptor.
2009-07-03 GO:0005499 vitamin D binding Added DEFINITION Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
2009-07-03 GO:0005506 iron ion binding Added DEFINITION Interacting selectively and non-covalently with iron (Fe) ions.
2009-07-03 GO:0005527 macrolide binding Added DEFINITION Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.
2009-07-03 GO:0008262 importin-alpha export receptor activity Added DEFINITION Interacting selectively and non-covalently with importin-alpha to mediate its transfer through the nuclear pore to the cytoplasm.
2009-07-03 GO:0008317 gurken receptor binding Added DEFINITION Interacting selectively and non-covalently with the gurken growth factor receptor.
2009-07-03 GO:0008368 Gram-negative bacterial binding Added DEFINITION Interacting selectively and non-covalently with any part of a Gram-negative bacterial cell.
2009-07-03 GO:0008430 selenium binding Added DEFINITION Interacting selectively and non-covalently with selenium (Se).
2009-07-03 GO:0009374 biotin binding Added DEFINITION Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2009-07-03 GO:0010013 N-1-naphthylphthalamic acid binding Added DEFINITION Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor.
2009-07-03 GO:0010331 gibberellin binding Added DEFINITION Interacting selectively and non-covalently with gibberellins, plant hormones that regulate aspects of plant growth.
2009-07-03 GO:0016151 nickel cation binding Added DEFINITION Interacting selectively and non-covalently with nickel (Ni) ions.
2009-07-03 GO:0016208 AMP binding Added DEFINITION Interacting selectively and non-covalently with AMP, adenosine monophosphate.
2009-07-03 GO:0016595 glutamate binding Added DEFINITION Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.
2009-07-03 GO:0017075 syntaxin-1 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-1.
2009-07-03 GO:0017134 fibroblast growth factor binding Added DEFINITION Interacting selectively and non-covalently with fibroblast growth factor.
2009-07-03 GO:0017137 Rab GTPase binding Added DEFINITION Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
2009-07-03 GO:0019002 GMP binding Added DEFINITION Interacting selectively and non-covalently with GMP, guanosine monophosphate.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2009-07-03 GO:0006948 induction by virus of host cell-cell fusion Updated TERM induction by virus of host cell-cell fusion
2009-07-03 GO:0006018 2-deoxyribose 1-phosphate catabolic process Updated TERM 2-deoxyribose 1-phosphate catabolic process
2009-07-03 GO:0030581 symbiont intracellular protein transport in host Updated TERM symbiont intracellular protein transport in host
2009-07-03 GO:0044000 movement in host Updated TERM movement in host
2009-07-03 GO:0044001 migration in host Updated TERM migration in host
2009-07-03 GO:0033665 regulation of growth or development of symbiont in host Updated TERM regulation of growth or development of symbiont in host
2009-07-03 GO:0033666 positive regulation of growth or development of symbiont in host Updated TERM positive regulation of growth or development of symbiont in host
2009-07-03 GO:0033667 negative regulation of growth or development of symbiont in host Updated TERM negative regulation of growth or development of symbiont in host
2009-07-03 GO:0052242 chemotaxis in other organism involved in symbiotic interaction Updated TERM chemotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052244 negative energy taxis in other organism involved in symbiotic interaction Updated TERM negative energy taxis in other organism during symbiotic interaction
2009-07-03 GO:0052247 positive energy taxis in other organism involved in symbiotic interaction Updated TERM positive energy taxis in other organism during symbiotic interaction
2009-07-03 GO:0052334 modification by organism of cytoskeleton of other organism involved in symbiotic interaction Updated TERM modification by organism of cytoskeleton of other organism during symbiotic interaction
2009-07-03 GO:0052533 positive regulation by symbiont of host induced systemic resistance Updated TERM positive regulation by symbiont of host induced systemic resistance
2009-07-03 GO:0052537 positive regulation by symbiont of host systemic acquired resistance Updated TERM positive regulation by symbiont of host systemic acquired resistance
2009-07-03 GO:0052018 modulation by symbiont of RNA levels in host Updated TERM modulation by symbiont of RNA levels in host
2009-07-03 GO:0052103 induction by symbiont of host induced systemic resistance Updated TERM induction by symbiont of host induced systemic resistance
2009-07-03 GO:0052104 induction by symbiont of host systemic acquired resistance Updated TERM induction by symbiont of host systemic acquired resistance
2009-07-03 GO:0052133 positive aerotaxis in host Updated TERM positive aerotaxis in host
2009-07-03 GO:0052135 negative aerotaxis in host Updated TERM negative aerotaxis in host
2009-07-03 GO:0052137 aerotaxis in host Updated TERM aerotaxis in host
2009-07-03 GO:0052139 negative chemotaxis in host Updated TERM negative chemotaxis in host
2009-07-03 GO:0052140 positive chemotaxis in host Updated TERM positive chemotaxis in host
2009-07-03 GO:0052144 negative energy taxis in host Updated TERM negative energy taxis in host
2009-07-03 GO:0052147 positive energy taxis in host Updated TERM positive energy taxis in host
2009-07-03 GO:0052159 modulation by symbiont of host induced systemic resistance Updated TERM modulation by symbiont of host induced systemic resistance
2009-07-03 GO:0052160 modulation by symbiont of host systemic acquired resistance Updated TERM modulation by symbiont of host systemic acquired resistance
2009-07-03 GO:0052224 energy taxis in other organism involved in symbiotic interaction Updated TERM energy taxis in other organism during symbiotic interaction
2009-07-03 GO:0052233 positive aerotaxis in other organism involved in symbiotic interaction Updated TERM positive aerotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052235 negative aerotaxis in other organism involved in symbiotic interaction Updated TERM negative aerotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052237 aerotaxis in other organism involved in symbiotic interaction Updated TERM aerotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052239 negative chemotaxis in other organism involved in symbiotic interaction Updated TERM negative chemotaxis in other organism during symbiotic interaction
2009-07-03 GO:0052240 positive chemotaxis in other organism involved in symbiotic interaction Updated TERM positive chemotaxis in other organism during symbiotic interaction
2009-07-03 GO:0051814 movement in other organism involved in symbiotic interaction Updated TERM movement in other organism during symbiotic interaction
2009-07-03 GO:0051815 migration in other organism involved in symbiotic interaction Updated TERM migration in other organism during symbiotic interaction
2009-07-03 GO:0051831 growth or development in other organism during symbiotic interaction Updated TERM growth or development in other organism during symbiotic interaction
2009-07-03 GO:0046388 deoxyribose 1-phosphate metabolic process Deleted TERM deoxyribose 1-phosphate metabolic process
2009-07-03 GO:0046733 passive induction of host humoral immune response by virus Updated TERM passive induction of host humoral immune response by virus
2009-07-03 GO:0046734 passive induction of host cell-mediated immune response by virus Updated TERM passive induction of host cell-mediated immune response by virus
2009-07-03 GO:0046735 passive induction of host innate immune response by virus Updated TERM passive induction of host innate immune response by virus
2009-07-03 GO:0046739 transport of virus in multicellular host Updated TERM spread of virus in host
2009-07-03 GO:0046740 transport of virus in host, cell to cell Updated TERM spread of virus in host, cell to cell
2009-07-03 GO:0046741 transport of virus in host, tissue to tissue Updated TERM spread of virus in host, tissue to tissue
2009-07-03 GO:0046774 suppression by virus of host intracellular interferon activity Updated TERM suppression by virus of host intracellular interferon activity
2009-07-03 GO:0046776 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Updated TERM suppression by virus of host MHC class I cell surface presentation
2009-07-03 GO:0044412 growth or development of symbiont in host Updated TERM growth or development of symbiont in host
2009-07-03 GO:0070359 actin polymerization-dependent cell motility involved in migration of symbiont in host Updated TERM actin polymerization-dependent cell motility involved in migration of symbiont in host
2009-07-03 GO:0070772 PAS complex Added TERM PAS complex
2009-07-03 GO:0070773 protein-N-terminal glutamine amidohydrolase activity Added TERM protein N-terminal glutamine amidohydrolase activity
2009-07-03 GO:0070774 phytoceramidase activity Added TERM phytoceramidase activity
2009-07-03 GO:0070775 H3 histone acetyltransferase complex Added TERM H3 histone acetyltransferase complex
2009-07-03 GO:0070776 MOZ/MORF histone acetyltransferase complex Added TERM MOZ/MORF histone acetyltransferase complex
2009-07-03 GO:0070777 D-aspartate transport Added TERM D-aspartate transport
2009-07-03 GO:0070778 L-aspartate transport Added TERM L-aspartate transport
2009-07-03 GO:0070779 D-aspartate import Added TERM D-aspartate import
2009-07-03 GO:0070780 dihydrosphingosine-1-phosphate phosphatase activity Added TERM dihydrosphingosine-1-phosphate phosphatase activity
2009-07-03 GO:0070781 response to biotin Added TERM response to biotin
2009-07-03 GO:0070782 phosphatidylserine exposure on apoptotic cell surface Added TERM phosphatidylserine exposure on apoptotic cell surface
2009-07-03 GO:0075061 formation of symbiont invasive hypha in host Updated TERM formation of symbiont invasive hypha in host
2009-07-03 GO:0075062 regulation of symbiont invasive hypha formation in host Updated TERM regulation of symbiont invasive hypha formation in host
2009-07-03 GO:0075063 positive regulation of symbiont invasive hypha formation in host Updated TERM positive regulation of symbiont invasive hypha formation in host
2009-07-03 GO:0075064 negative regulation of symbiont invasive hypha formation in host Updated TERM negative regulation of symbiont invasive hypha formation in host

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2009-07-03 GO:0048029 monosaccharide binding Deleted DEFINITION Interacting selectively with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
2009-07-03 GO:0050662 coenzyme binding Deleted DEFINITION Interacting selectively with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
2009-07-03 GO:0000401 open form four-way junction DNA binding Deleted DEFINITION Interacting selectively with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.
2009-07-03 GO:0031723 CXCR4 chemokine receptor binding Deleted DEFINITION Interacting selectively with a CXCR4 chemokine receptor.
2009-07-03 GO:0031755 Edg-2 lysophosphatidic acid receptor binding Deleted DEFINITION Interacting selectively with an Edg-2 lysophosphatidic acid receptor.
2009-07-03 GO:0031750 D3 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D3 dopamine receptor.
2009-07-03 GO:0045236 CXCR chemokine receptor binding Deleted DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2009-07-03 GO:0070742 C2H2 zinc finger domain binding Deleted DEFINITION Interacting selectively with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
2009-07-03 GO:0051375 FATZ 2 binding Deleted DEFINITION Interacting selectively with FATZ 2, a protein of the FATZ family that is highly expressed in skeletal muscle fiber fast IIa and slow I and in cardiac muscle.
2009-07-03 GO:0031855 oxytocin receptor binding Deleted DEFINITION Interacting selectively with an oxytocin receptor.
2009-07-03 GO:0031811 G-protein coupled nucleotide receptor binding Deleted DEFINITION Interacting selectively with a metabotropic nucleotide receptor.
2009-07-03 GO:0070095 fructose-6-phosphate binding Deleted DEFINITION Interacting selectively with fructose 6-phosphate.
2009-07-03 GO:0043531 ADP binding Deleted DEFINITION Interacting selectively with ADP, adenosine 5'-diphosphate.
2009-07-03 GO:0042806 fucose binding Deleted DEFINITION Interacting selectively with fucose, the pentose 6-deoxygalactose.
2009-07-03 GO:0046870 cadmium ion binding Deleted DEFINITION Interacting selectively with cadmium (Cd) ions.
2009-07-03 GO:0042562 hormone binding Deleted DEFINITION Interacting selectively with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
2009-07-03 GO:0051528 NFAT3 protein binding Deleted DEFINITION Interacting selectively with NFAT3 (nuclear factor of activated T cells 3 protein), a calcium-regulated protein which acts as a transcription factor.
2009-07-03 GO:0035091 phosphatidylinositol binding Deleted DEFINITION Interacting selectively with any inositol-containing glycerophospholipid.
2009-07-03 GO:0031803 type 6 metabotropic glutamate receptor binding Deleted DEFINITION Interacting selectively with a type 6 metabotropic glutamate receptor.
2009-07-03 GO:0031418 L-ascorbic acid binding Deleted DEFINITION Interacting selectively with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
2009-07-03 GO:0005111 type 2 fibroblast growth factor receptor binding Deleted DEFINITION Interacting selectively with the type 2 fibroblast growth factor receptor (FGFR2).
2009-07-03 GO:0005175 CD27 receptor binding Deleted DEFINITION Interacting selectively with a CD27, a receptor found on the surface of T cells and some B cells and NK cells.
2009-07-03 GO:0031473 myosin III binding Deleted DEFINITION Interacting selectively with a class III myosin; myosin III is monomeric and has an N terminal kinase domain.
2009-07-03 GO:0008017 microtubule binding Deleted DEFINITION Interacting selectively with microtubules, filaments composed of tubulin monomers.
2009-07-03 GO:0045510 interleukin-24 binding Deleted DEFINITION Interacting selectively with interleukin-24.
2009-07-03 GO:0031768 ghrelin receptor binding Deleted DEFINITION Interacting selectively with a ghrelin receptor.
2009-07-03 GO:0031701 angiotensin receptor binding Deleted DEFINITION Interacting selectively with an angiotensin receptor.
2009-07-03 GO:0031733 CCR8 chemokine receptor binding Deleted DEFINITION Interacting selectively with a CCR8 chemokine receptor.
2009-07-03 GO:0005169 neurotrophin TRKB receptor binding Deleted DEFINITION Interacting selectively with the neurotrophin TRKB receptor.
2009-07-03 GO:0005506 iron ion binding Deleted DEFINITION Interacting selectively with iron (Fe) ions.
2009-07-03 GO:0042923 neuropeptide binding Deleted DEFINITION Interacting selectively and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).
2009-07-03 GO:0032190 acrosin binding Deleted DEFINITION Interacting selectively with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.
2009-07-03 GO:0008097 5S rRNA binding Deleted DEFINITION Interacting selectively with 5S ribosomal RNA, the smallest RNA constituent of a ribosome.
2009-07-03 GO:0031751 D4 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D4 dopamine receptor.
2009-07-03 GO:0033295 hydroxyectoine binding Deleted DEFINITION Interacting selectively with hydroxyectoine.
2009-07-03 GO:0031864 EP1 subtype prostaglandin E2 receptor binding Deleted DEFINITION Interacting selectively with an EP1 subtype prostaglandin E2 receptor.
2009-07-03 GO:0050681 androgen receptor binding Deleted DEFINITION Interacting selectively with an androgen receptor.
2009-07-03 GO:0031760 Edg-7 lysophosphatidic acid receptor binding Deleted DEFINITION Interacting selectively with an Edg-7 lysophosphatidic acid receptor.
2009-07-03 GO:0045519 interleukin-23 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-23 receptor.
2009-07-03 GO:0043295 glutathione binding Deleted DEFINITION Interacting selectively with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.
2009-07-03 GO:0033204 ribonuclease P RNA binding Deleted DEFINITION Interacting selectively with the RNA subunit of ribonuclease P.
2009-07-03 GO:0043395 heparan sulfate proteoglycan binding Deleted DEFINITION Interacting selectively with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
2009-07-03 GO:0031702 type 1 angiotensin receptor binding Deleted DEFINITION Interacting selectively with a type 1 angiotensin receptor.
2009-07-03 GO:0070644 vitamin D response element binding Deleted DEFINITION Interacting selectively with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
2009-07-03 GO:0033613 activating transcription factor binding Deleted DEFINITION Interacting selectively with a transcription activator, any protein whose activity is required to initiate or upregulate transcription.
2009-07-03 GO:0015643 toxic substance binding Deleted DEFINITION Interacting selectively with a toxin, a poisonous substance that causes damage to biological systems. Toxins are differentiated from simple chemical poisons and vegetable alkaloids by their high molecular weight and antigenicity (they elicit an antibody response).
2009-07-03 GO:0042162 telomeric DNA binding Deleted DEFINITION Interacting selectively with telomere-associated DNA, usually characterized by highly repetitive sequences.
2009-07-03 GO:0043522 leucine zipper domain binding Deleted DEFINITION Interacting selectively with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns.
2009-07-03 GO:0030629 U6 snRNA 3'-end binding Deleted DEFINITION Interacting selectively with the 3' end of the U6 small nuclear RNA (U6 snRNA).
2009-07-03 GO:0001851 complement component C3b binding Deleted DEFINITION Interacting selectively with the C3b product of the complement cascade.
2009-07-03 GO:0031773 kisspeptin receptor binding Deleted DEFINITION Interacting selectively with a kisspeptin receptor.
2009-07-03 GO:0048495 Roundabout binding Deleted DEFINITION Interacting selectively with the Roundabout (ROBO) receptor, a transmembrane receptor.
2009-07-03 GO:0005110 frizzled-2 binding Deleted DEFINITION Interacting selectively with frizzled-2 (fz2).
2009-07-03 GO:0005536 glucose binding Deleted DEFINITION Interacting selectively with the D- or L-enantiomer of glucose.
2009-07-03 GO:0002061 pyrimidine nucleobase binding Deleted DEFINITION Interacting selectively with a pyrimidine, an organic nitrogenous base.
2009-07-03 GO:0051861 glycolipid binding Deleted DEFINITION Interacting selectively with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.
2009-07-03 GO:0031840 type 2 neuromedin U receptor binding Deleted DEFINITION Interacting selectively with a type 2 neuromedin U receptor.
2009-07-03 GO:0042379 chemokine receptor binding Deleted DEFINITION Interacting selectively with any chemokine receptor.
2009-07-03 GO:0045517 interleukin-20 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-20 receptor.
2009-07-03 GO:0045569 TRAIL binding Deleted DEFINITION Interacting selectively with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.
2009-07-03 GO:0001856 complement component C5a binding Deleted DEFINITION Interacting selectively with the C5a product of the complement cascade.
2009-07-03 GO:0001862 collectin binding Deleted DEFINITION Interacting selectively with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.
2009-07-03 GO:0008035 high-density lipoprotein particle binding Deleted DEFINITION Interacting selectively with high-density lipoprotein: one of the classes of lipoproteins found in blood plasma in many animals (data normally relate to humans).
2009-07-03 GO:0016169 bacteriochlorophyll c binding Deleted DEFINITION Interacting selectively with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.
2009-07-03 GO:0051787 misfolded protein binding Deleted DEFINITION Interacting selectively with a misfolded protein.
2009-07-03 GO:0000149 SNARE binding Deleted DEFINITION Interacting selectively with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
2009-07-03 GO:0051530 NFAT5 protein binding Deleted DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a member of the NFAT transcription factor family which is not calcium regulated.
2009-07-03 GO:0045504 dynein heavy chain binding Deleted DEFINITION Interacting selectively with a heavy chain of the dynein complex.
2009-07-03 GO:0017137 Rab GTPase binding Deleted DEFINITION Interacting selectively with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
2009-07-03 GO:0005146 leukemia inhibitory factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the leukemia inhibitory factor receptor.
2009-07-03 GO:0070300 phosphatidic acid binding Deleted DEFINITION Interacting selectively with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
2009-07-03 GO:0032794 GTPase activating protein binding Deleted DEFINITION Interacting selectively with a GTPase activating protein.
2009-07-03 GO:0000498 base pairing with RNA Deleted DEFINITION Interacting selectively with ribonucleic acid (RNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target RNA molecule.
2009-07-03 GO:0032564 dATP binding Deleted DEFINITION Interacting selectively with dATP, deoxyadenosine triphosphate.
2009-07-03 GO:0042835 BRE binding Deleted DEFINITION Interacting selectively with the RNA element BRE (Bruno response element).
2009-07-03 GO:0005497 androgen binding Added DEFINITION Interacting selectively and non-covalently with any androgen, male sex hormones.
2009-07-03 GO:0005507 copper ion binding Added DEFINITION Interacting selectively and non-covalently with copper (Cu) ions.
2009-07-03 GO:0005518 collagen binding Added DEFINITION Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2009-07-03 GO:0005521 lamin binding Added DEFINITION Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
2009-07-03 GO:0005524 ATP binding Added DEFINITION Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2009-07-03 GO:0005549 odorant binding Added DEFINITION Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell.
2009-07-03 GO:0005550 pheromone binding Added DEFINITION Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
2009-07-03 GO:0008022 protein C-terminus binding Added DEFINITION Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2009-07-03 GO:0008144 drug binding Added DEFINITION Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2009-07-03 GO:0008198 ferrous iron binding Added DEFINITION Interacting selectively and non-covalently with ferrous iron, Fe(II).
2009-07-03 GO:0008431 vitamin E binding Added DEFINITION Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
2009-07-03 GO:0010314 phosphatidylinositol-5-phosphate binding Added DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a phosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0010843 promoter binding Added DEFINITION Interacting selectively and non-covalently within the regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery.
2009-07-03 GO:0010844 recombination hotspot binding Added DEFINITION Interacting selectively and non-covalently with a region in a genome which promotes recombination.
2009-07-03 GO:0016936 galactoside binding Added DEFINITION Interacting selectively and non-covalently with any glycoside in which the sugar moiety is galactose.
2009-07-03 GO:0017022 myosin binding Added DEFINITION Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
2009-07-03 GO:0017046 peptide hormone binding Added DEFINITION Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
2009-07-03 GO:0017049 GTP-Rho binding Added DEFINITION Interacting selectively and non-covalently with the GTP-bound form of the Rho protein.
2009-07-03 GO:0017058 FH1 domain binding Added DEFINITION Interacting selectively and non-covalently with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.
2009-07-03 GO:0019826 oxygen sensor activity Added DEFINITION Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).
2009-07-03 GO:0019862 IgA binding Added DEFINITION Interacting selectively and non-covalently with an immunoglobulin of an IgA isotype.
2009-07-03 GO:0019902 phosphatase binding Added DEFINITION Interacting selectively and non-covalently with any phosphatase.
2009-07-03 GO:0019956 chemokine binding Added DEFINITION Interacting selectively and non-covalently with a chemokine, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions.
2009-07-03 GO:0019964 interferon-gamma binding Added DEFINITION Interacting selectively and non-covalently with interferon-gamma. Interferon-gamma is also known as type II interferon.
2009-07-03 GO:0019978 interleukin-3 binding Added DEFINITION Interacting selectively and non-covalently with interleukin-3.
2009-07-03 GO:0019980 interleukin-5 binding Added DEFINITION Interacting selectively and non-covalently with interleukin-5.
2009-07-03 GO:0030215 semaphorin receptor binding Added DEFINITION Interacting selectively and non-covalently with semaphorin receptors.
2009-07-03 GO:0030306 ADP-ribosylation factor binding Added DEFINITION Interacting selectively and non-covalently with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells.
2009-07-03 GO:0030331 estrogen receptor binding Added DEFINITION Interacting selectively and non-covalently with an estrogen receptor.
2009-07-03 GO:0030348 syntaxin-3 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-3.
2009-07-03 GO:0030370 intercellular adhesion molecule-3 receptor binding Added DEFINITION Interacting selectively and non-covalently with receptors for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1.
2009-07-03 GO:0030911 TPR domain binding Added DEFINITION Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.
2009-07-03 GO:0030984 kininogen binding Added DEFINITION Interacting selectively and non-covalently with a kininogen, any of a group of plasma proteins that are kinin precursors.
2009-07-03 GO:0030986 low molecular weight kininogen binding Added DEFINITION Interacting selectively and non-covalently with a kininogen of low molecular mass.
2009-07-03 GO:0031005 filamin binding Added DEFINITION Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.
2009-07-03 GO:0031418 L-ascorbic acid binding Added DEFINITION Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
2009-07-03 GO:0031493 nucleosomal histone binding Added DEFINITION Interacting selectively and non-covalently with a histone that is assembled into a nucleosome.
2009-07-03 GO:0031593 polyubiquitin binding Added DEFINITION Interacting selectively and non-covalently and non-covalently with a polymer of ubiqutin.
2009-07-03 GO:0031682 G-protein gamma-subunit binding Added DEFINITION Interacting selectively and non-covalently with a G-protein gamma subunit.
2009-07-03 GO:0031691 alpha-1A adrenergic receptor binding Added DEFINITION Interacting selectively and non-covalently with an alpha-1A adrenergic receptor.
2009-07-03 GO:0031695 alpha-2B adrenergic receptor binding Added DEFINITION Interacting selectively and non-covalently with an alpha-2B adrenergic receptor.
2009-07-03 GO:0031700 adrenomedullin receptor binding Added DEFINITION Interacting selectively and non-covalently with an adrenomedullin receptor.
2009-07-03 GO:0031712 B1 bradykinin receptor binding Added DEFINITION Interacting selectively and non-covalently with a B1 bradykinin receptor.
2009-07-03 GO:0031717 cannabinoid receptor binding Added DEFINITION Interacting selectively and non-covalently with a cannabinoid receptor.
2009-07-03 GO:0031726 CCR1 chemokine receptor binding Added DEFINITION Interacting selectively and non-covalently with a CCR1 chemokine receptor.
2009-07-03 GO:0031741 type B gastrin/cholecystokinin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type B gastrin/cholecystokinin receptor.
2009-07-03 GO:0031752 D5 dopamine receptor binding Added DEFINITION Interacting selectively and non-covalently with a D5 dopamine receptor.
2009-07-03 GO:0031757 Edg-4 lysophosphatidic acid receptor binding Added DEFINITION Interacting selectively and non-covalently with an Edg-4 lysophosphatidic acid receptor.
2009-07-03 GO:0031766 type 3 galanin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 3 galanin receptor.
2009-07-03 GO:0031781 type 3 melanocortin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 3 melanocortin receptor.
2009-07-03 GO:0031783 type 5 melanocortin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 5 melanocortin receptor.
2009-07-03 GO:0031784 melatonin receptor binding Added DEFINITION Interacting selectively and non-covalently with a melatonin receptor.
2009-07-03 GO:0031799 type 2 metabotropic glutamate receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 2 metabotropic glutamate receptor.
2009-07-03 GO:0031804 type 7 metabotropic glutamate receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 7 metabotropic glutamate receptor.
2009-07-03 GO:0031828 type 2C serotonin receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 2C serotonin receptor.
2009-07-03 GO:0031861 prolactin-releasing peptide receptor binding Added DEFINITION Interacting selectively and non-covalently with a prolactin-releasing peptide receptor.
2009-07-03 GO:0031864 EP1 subtype prostaglandin E2 receptor binding Added DEFINITION Interacting selectively and non-covalently with an EP1 subtype prostaglandin E2 receptor.
2009-07-03 GO:0031870 thromboxane A2 receptor binding Added DEFINITION Interacting selectively and non-covalently with a thromboxane A2 receptor.
2009-07-03 GO:0031884 type 1 member 1 taste receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 1 member 1 taste receptor.
2009-07-03 GO:0051525 NFAT protein binding Deleted DEFINITION Interacting selectively with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
2009-07-03 GO:0002020 protease binding Deleted DEFINITION Interacting selectively with any protease or peptidase.
2009-07-03 GO:0034189 very-low-density lipoprotein particle binding Deleted DEFINITION Interacting selectively with very-low-density lipoprotein, one of the classes of lipoproteins found in blood plasma in many animals.
2009-07-03 GO:0005540 hyaluronic acid binding Deleted DEFINITION Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
2009-07-03 GO:0000822 inositol hexakisphosphate binding Deleted DEFINITION Interacting selectively with inositol hexakisphosphate.
2009-07-03 GO:0005509 calcium ion binding Deleted DEFINITION Interacting selectively with calcium ions (Ca2+).
2009-07-03 GO:0051419 nebulin binding Deleted DEFINITION Interacting selectively with nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone.
2009-07-03 GO:0017033 DNA topoisomerase I binding Deleted DEFINITION Interacting selectively with the enzyme DNA topoisomerase I.
2009-07-03 GO:0032795 heterotrimeric G-protein binding Deleted DEFINITION Interacting selectively with a heterotrimeric G-protein.
2009-07-03 GO:0051393 alpha-actinin binding Deleted DEFINITION Interacting selectively with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
2009-07-03 GO:0005524 ATP binding Deleted DEFINITION Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2009-07-03 GO:0051526 NFAT1 protein binding Deleted DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a calcium-regulated protein which acts as a transcription factor.
2009-07-03 GO:0030941 chloroplast targeting sequence binding Deleted DEFINITION Interacting selectively with a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast.
2009-07-03 GO:0017069 snRNA binding Deleted DEFINITION Interacting selectively with a small nuclear RNA (snRNA).
2009-07-03 GO:0051430 corticotropin-releasing hormone receptor 1 binding Deleted DEFINITION Interacting selectively with the protein corticotropin-releasing hormone receptor 1 (CRHR1). The CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on adrenocorticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.
2009-07-03 GO:0031857 type 1 parathyroid hormone receptor binding Deleted DEFINITION Interacting selectively with a type 1 parathyroid hormone receptor.
2009-07-03 GO:0031875 type 4 proteinase activated receptor binding Deleted DEFINITION Interacting selectively with a type 4 proteinase activated receptor.
2009-07-03 GO:0051435 BH4 domain binding Deleted DEFINITION Interacting selectively with the BH4 domain of a protein of the Bcl-2 family. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.
2009-07-03 GO:0050811 GABA receptor binding Deleted DEFINITION Interacting selectively with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
2009-07-03 GO:0032136 adenine/cytosine mispair binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing an A/C mispair.
2009-07-03 GO:0032408 MutSbeta complex binding Deleted DEFINITION Interacting selectively with the mismatch repair complex MutSbeta.
2009-07-03 GO:0019981 interleukin-6 binding Deleted DEFINITION Interacting selectively with interleukin-6.
2009-07-03 GO:0031762 follicle-stimulating hormone receptor binding Deleted DEFINITION Interacting selectively with a follicle stimulating hormone receptor.
2009-07-03 GO:0030883 endogenous lipid antigen binding Deleted DEFINITION Interacting selectively with an endogenous cellular lipid antigen.
2009-07-03 GO:0030348 syntaxin-3 binding Deleted DEFINITION Interacting selectively with the SNAP receptor syntaxin-3.
2009-07-03 GO:0032548 pyrimidine deoxyribonucleoside binding Deleted DEFINITION Interacting selectively with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.
2009-07-03 GO:0005133 interferon-gamma receptor binding Deleted DEFINITION Interacting selectively with the interferon-gamma receptor.
2009-07-03 GO:0031784 melatonin receptor binding Deleted DEFINITION Interacting selectively with a melatonin receptor.
2009-07-03 GO:0032137 guanine/thymine mispair binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing a G/T mispair.
2009-07-03 GO:0031876 secretin receptor binding Deleted DEFINITION Interacting selectively with a secretin receptor.
2009-07-03 GO:0043515 kinetochore binding Deleted DEFINITION Interacting selectively with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.
2009-07-03 GO:0032028 myosin head/neck binding Deleted DEFINITION Interacting selectively with the head/neck region of a myosin heavy chain.
2009-07-03 GO:0032031 myosin I head/neck binding Deleted DEFINITION Interacting selectively with the head/neck region of a myosin I heavy chain.
2009-07-03 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Deleted DEFINITION Interacting selectively with the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein.
2009-07-03 GO:0031721 hemoglobin alpha binding Deleted DEFINITION Interacting selectively with a hemoglobin alpha chain.
2009-07-03 GO:0031764 type 1 galanin receptor binding Deleted DEFINITION Interacting selectively with a type 1 galanin receptor.
2009-07-03 GO:0032181 dinucleotide repeat insertion binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.
2009-07-03 GO:0032143 single thymine insertion binding Deleted DEFINITION Interacting selectively with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine.
2009-07-03 GO:0031782 type 4 melanocortin receptor binding Deleted DEFINITION Interacting selectively with a type 4 melanocortin receptor.
2009-07-03 GO:0050824 water binding Deleted DEFINITION Interacting selectively with water (H2O).
2009-07-03 GO:0019841 retinol binding Deleted DEFINITION Interacting selectively with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
2009-07-03 GO:0031765 type 2 galanin receptor binding Deleted DEFINITION Interacting selectively with a type 2 galanin receptor.
2009-07-03 GO:0045521 interleukin-25 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-25 receptor.
2009-07-03 GO:0042021 granulocyte macrophage colony-stimulating factor complex binding Deleted DEFINITION Interacting selectively with the granulocyte macrophage colony-stimulating factor complex.
2009-07-03 GO:0070051 fibrinogen binding Deleted DEFINITION Interacting selectively with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.
2009-07-03 GO:0031882 type 5 somatostatin receptor binding Deleted DEFINITION Interacting selectively with a type 5 somatostatin receptor.
2009-07-03 GO:0043120 tumor necrosis factor binding Deleted DEFINITION Interacting selectively with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.
2009-07-03 GO:0031819 P2Y10 nucleotide receptor binding Deleted DEFINITION Interacting selectively with a P2Y10 nucleotide receptor.
2009-07-03 GO:0005119 smoothened binding Deleted DEFINITION Interacting selectively with the smoothened (smo) protein, which interacts with patched to transmit hedgehog signals.
2009-07-03 GO:0032406 MutLbeta complex binding Deleted DEFINITION Interacting selectively with the mismatch repair complex MutLbeta.
2009-07-03 GO:0035254 glutamate receptor binding Deleted DEFINITION Interacting selectively with a glutamate receptor.
2009-07-03 GO:0042657 MHC class II protein binding, via lateral surface Deleted DEFINITION Interacting selectively with the lateral surface of major histocompatibility complex class II molecules.
2009-07-03 GO:0005529 sugar binding Deleted DEFINITION Interacting selectively with any mono-, di- or trisaccharide carbohydrate.
2009-07-03 GO:0031874 type 3 proteinase activated receptor binding Deleted DEFINITION Interacting selectively with a type 3 proteinase activated receptor.
2009-07-03 GO:0005519 cytoskeletal regulatory protein binding Deleted DEFINITION Interacting selectively with any protein involved in modulating the reorganization of the cytoskeleton.
2009-07-03 GO:0031738 XCR1 chemokine receptor binding Deleted DEFINITION Interacting selectively with a XCR1 chemokine receptor.
2009-07-03 GO:0030975 thiamine binding Deleted DEFINITION Interacting selectively with thiamin (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
2009-07-03 GO:0005046 KDEL sequence binding Deleted DEFINITION Interacting selectively with a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
2009-07-03 GO:0031885 type 1 member 2 taste receptor binding Added DEFINITION Interacting selectively and non-covalently with a type 1 member 2 taste receptor.
2009-07-03 GO:0031961 cortisol receptor binding Added DEFINITION Interacting selectively and non-covalently with a cortisol receptor.
2009-07-03 GO:0031996 thioesterase binding Added DEFINITION Interacting selectively and non-covalently with any thioesterase enzyme.
2009-07-03 GO:0031997 N-terminal myristoylation domain binding Added DEFINITION Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.
2009-07-03 GO:0032028 myosin head/neck binding Added DEFINITION Interacting selectively and non-covalently with the head/neck region of a myosin heavy chain.
2009-07-03 GO:0032037 myosin I heavy chain binding Added DEFINITION Interacting selectively and non-covalently with a heavy chain of a myosin I complex.
2009-07-03 GO:0005149 interleukin-1 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-1 receptor.
2009-07-03 GO:0005161 platelet-derived growth factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
2009-07-03 GO:0005170 neurotrophin TRKC receptor binding Added DEFINITION Interacting selectively and non-covalently with the neurotrophin TRKC receptor.
2009-07-03 GO:0005483 soluble NSF attachment protein activity Added DEFINITION Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.
2009-07-03 GO:0005496 steroid binding Added DEFINITION Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
2009-07-03 GO:0051015 actin filament binding Deleted DEFINITION Interacting selectively with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2009-07-03 GO:0043274 phospholipase binding Deleted DEFINITION Interacting selectively with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.
2009-07-03 GO:0043184 vascular endothelial growth factor receptor 2 binding Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2009-07-03 GO:0031878 type 1 somatostatin receptor binding Deleted DEFINITION Interacting selectively with a type 1 somatostatin receptor.
2009-07-03 GO:0032038 myosin II heavy chain binding Deleted DEFINITION Interacting selectively with a heavy chain of a myosin II complex.
2009-07-03 GO:0051378 serotonin binding Deleted DEFINITION Interacting selectively with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
2009-07-03 GO:0043130 ubiquitin binding Deleted DEFINITION Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
2009-07-03 GO:0031788 motilin receptor binding Deleted DEFINITION Interacting selectively with a motilin receptor.
2009-07-03 GO:0031801 type 4 metabotropic glutamate receptor binding Deleted DEFINITION Interacting selectively with a type 4 metabotropic glutamate receptor.
2009-07-03 GO:0019864 IgG binding Deleted DEFINITION Interacting selectively with an immunoglobulin of an IgG isotype.
2009-07-03 GO:0001968 fibronectin binding Deleted DEFINITION Interacting selectively with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
2009-07-03 GO:0050544 arachidonic acid binding Deleted DEFINITION Interacting selectively with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
2009-07-03 GO:0031722 hemoglobin beta binding Deleted DEFINITION Interacting selectively with a hemoglobin beta chain.
2009-07-03 GO:0032137 guanine/thymine mispair binding Added DEFINITION Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair.
2009-07-03 GO:0032403 protein complex binding Added DEFINITION Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2009-07-03 GO:0032422 purine-rich negative regulatory element binding Added DEFINITION Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
2009-07-03 GO:0032448 DNA hairpin binding Added DEFINITION Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.
2009-07-03 GO:0032547 purine deoxyribonucleoside binding Added DEFINITION Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.
2009-07-03 GO:0032552 deoxyribonucleotide binding Added DEFINITION Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
2009-07-03 GO:0032561 guanyl ribonucleotide binding Added DEFINITION Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
2009-07-03 GO:0033149 FFAT motif binding Added DEFINITION Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.
2009-07-03 GO:0033204 ribonuclease P RNA binding Added DEFINITION Interacting selectively and non-covalently with the RNA subunit of ribonuclease P.
2009-07-03 GO:0033219 urea binding Added DEFINITION Interacting selectively and non-covalently with urea, a water-soluble carboxamide with the structure H2N-CO-NH2.
2009-07-03 GO:0034187 apolipoprotein E binding Added DEFINITION Interacting selectively and non-covalently with apolipoprotein E.
2009-07-03 GO:0034237 protein kinase A regulatory subunit binding Added DEFINITION Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.
2009-07-03 GO:0034347 type III interferon binding Added DEFINITION Interacting selectively and non-covalently with a type III interferon. Type III interferons are members of the interferon-lambda gene family.
2009-07-03 GO:0034513 box H/ACA snoRNA binding Added DEFINITION Interacting selectively and non-covalently with box H/ACA small nucleolar RNA.
2009-07-03 GO:0034988 Fc-gamma receptor I complex binding Added DEFINITION Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.
2009-07-03 GO:0035240 dopamine binding Added DEFINITION Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.
2009-07-03 GO:0035257 nuclear hormone receptor binding Added DEFINITION Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.
2009-07-03 GO:0042287 MHC protein binding Added DEFINITION Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
2009-07-03 GO:0042393 histone binding Added DEFINITION Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2009-07-03 GO:0042605 peptide antigen binding Added DEFINITION Interacting selectively and non-covalently with an antigen peptide, a fragment of a foreign protein derived by proteolysis within the cell.
2009-07-03 GO:0042658 MHC class II protein binding, via antigen binding groove Added DEFINITION Interacting selectively and non-covalently with the antigen binding groove of major histocompatibility complex class II molecules.
2009-07-03 GO:0042834 peptidoglycan binding Added DEFINITION Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
2009-07-03 GO:0043022 ribosome binding Added DEFINITION Interacting selectively and non-covalently with any part of a ribosome.
2009-07-03 GO:0043024 ribosomal small subunit binding Added DEFINITION Interacting selectively and non-covalently with any part of the small ribosomal subunit.
2009-07-03 GO:0043035 chromatin insulator sequence binding Added DEFINITION Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
2009-07-03 GO:0043169 cation binding Added DEFINITION Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
2009-07-03 GO:0043178 alcohol binding Added DEFINITION Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group.
2009-07-03 GO:0043208 glycosphingolipid binding Added DEFINITION Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
2009-07-03 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding Added DEFINITION Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a diphosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0043498 cell surface binding Added DEFINITION Interacting selectively and non-covalently with any component on the surface of a cell.
2009-07-03 GO:0045015 HDEL sequence binding Added DEFINITION Interacting selectively and non-covalently with a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
2009-07-03 GO:0045159 myosin II binding Added DEFINITION Interacting selectively and non-covalently with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.
2009-07-03 GO:0045322 unmethylated CpG binding Added DEFINITION Interacting selectively and non-covalently with unmethylated CpG motifs. Unmethylated CpG dinucleotides are often associated with gene promoters.
2009-07-03 GO:0045502 dynein binding Added DEFINITION Interacting selectively and non-covalently with dynein, the multisubunit protein complex that is associated with microtubules.
2009-07-03 GO:0045521 interleukin-25 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-25 receptor.
2009-07-03 GO:0045522 interleukin-26 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-26 receptor.
2009-07-03 GO:0046980 tapasin binding Added DEFINITION Interacting selectively and non-covalently with tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules.
2009-07-03 GO:0048185 activin binding Added DEFINITION Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits.
2009-07-03 GO:0048273 mitogen-activated protein kinase p38 binding Added DEFINITION Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.
2009-07-03 GO:0048495 Roundabout binding Added DEFINITION Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.
2009-07-03 GO:0048602 fibroblast growth factor 1 binding Added DEFINITION Interacting selectively and non-covalently with fibroblast growth factor 1.
2009-07-03 GO:0050430 syntaxin-6 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-6.
2009-07-03 GO:0050543 icosatetraenoic acid binding Added DEFINITION Interacting selectively and non-covalently with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.
2009-07-03 GO:0050693 LBD domain binding Added DEFINITION Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.
2009-07-03 GO:0032399 HECT domain binding Deleted DEFINITION Interacting selectively with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein.
2009-07-03 GO:0003786 actin lateral binding Deleted DEFINITION Interacting selectively with an actin filament along its length.
2009-07-03 GO:0043560 insulin receptor substrate binding Deleted DEFINITION Interacting selectively with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.
2009-07-03 GO:0001884 pyrimidine nucleoside binding Deleted DEFINITION Interacting selectively with a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose.
2009-07-03 GO:0035259 glucocorticoid receptor binding Deleted DEFINITION Interacting selectively with a glucocorticoid receptor.
2009-07-03 GO:0002039 p53 binding Deleted DEFINITION Interacting selectively with one of the p53 family of proteins.
2009-07-03 GO:0043495 protein anchor Deleted DEFINITION Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
2009-07-03 GO:0034712 inhibin alpha binding Deleted DEFINITION Interacting selectively with inhibin alpha.
2009-07-03 GO:0016597 amino acid binding Deleted DEFINITION Interacting selectively with an amino acid, organic acids containing one or more amino substituents.
2009-07-03 GO:0051434 BH3 domain binding Deleted DEFINITION Interacting selectively with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.
2009-07-03 GO:0031749 D2 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D2 dopamine receptor.
2009-07-03 GO:0031863 prostaglandin D2 receptor binding Deleted DEFINITION Interacting selectively with a prostaglandin D2 receptor.
2009-07-03 GO:0008289 lipid binding Deleted DEFINITION Interacting selectively with a lipid.
2009-07-03 GO:0032403 protein complex binding Deleted DEFINITION Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2009-07-03 GO:0031846 neurotensin receptor binding Deleted DEFINITION Interacting selectively with a neurotensin receptor.
2009-07-03 GO:0051381 histamine binding Deleted DEFINITION Interacting selectively with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
2009-07-03 GO:0048607 fibroblast growth factor 6 binding Deleted DEFINITION Interacting selectively with fibroblast growth factor 6.
2009-07-03 GO:0005518 collagen binding Deleted DEFINITION Interacting selectively with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2009-07-03 GO:0031786 type 1B melatonin receptor binding Deleted DEFINITION Interacting selectively with a type 1B melatonin receptor.
2009-07-03 GO:0032145 succinate-semialdehyde dehydrogenase binding Deleted DEFINITION Interacting selectively with succinate-semialdehyde dehydrogenase.
2009-07-03 GO:0042019 interleukin-23 binding Deleted DEFINITION Interacting selectively with interleukin-23.
2009-07-03 GO:0005534 galactose binding Deleted DEFINITION Interacting selectively with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.
2009-07-03 GO:0030973 molybdate ion binding Deleted DEFINITION Interacting selectively with molybdate (MoO4 2-) ions.
2009-07-03 GO:0003785 actin monomer binding Deleted DEFINITION Interacting selectively with monomeric actin, also known as G-actin.
2009-07-03 GO:0000049 tRNA binding Deleted DEFINITION Interacting selectively with transfer RNA.
2009-07-03 GO:0048603 fibroblast growth factor 2 binding Deleted DEFINITION Interacting selectively with fibroblast growth factor 2.
2009-07-03 GO:0035198 miRNA binding Deleted DEFINITION Interacting selectively with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
2009-07-03 GO:0008134 transcription factor binding Deleted DEFINITION Interacting selectively with a transcription factor, any protein required to initiate or regulate transcription.
2009-07-03 GO:0000340 RNA 7-methylguanosine cap binding Deleted DEFINITION Interacting selectively with the 7-methylguanosine moiety added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.
2009-07-03 GO:0030619 U1 snRNA binding Deleted DEFINITION Interacting selectively with the U1 small nuclear RNA (U1 snRNA).
2009-07-03 GO:0008262 importin-alpha export receptor activity Deleted DEFINITION Interacting selectively with importin-alpha to mediate its transfer through the nuclear pore to the cytoplasm.
2009-07-03 GO:0045296 cadherin binding Deleted DEFINITION Interacting selectively with cadherin, a type I membrane protein involved in cell adhesion.
2009-07-03 GO:0030156 benzodiazepine receptor binding Deleted DEFINITION Interacting selectively with the peripheral benzodiazepine receptor (PBR).
2009-07-03 GO:0031852 mu-type opioid receptor binding Deleted DEFINITION Interacting selectively with a mu-type opioid receptor.
2009-07-03 GO:0005123 death receptor binding Deleted DEFINITION Interacting selectively with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).
2009-07-03 GO:0051370 ZASP binding Deleted DEFINITION Interacting selectively with Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain.
2009-07-03 GO:0031745 cysteinyl leukotriene receptor binding Deleted DEFINITION Interacting selectively with a cysteinyl leukotriene receptor.
2009-07-03 GO:0008317 gurken receptor binding Deleted DEFINITION Interacting selectively with the gurken growth factor receptor.
2009-07-03 GO:0033130 acetylcholine receptor binding Deleted DEFINITION Interacting selectively with an acetylcholine receptor.
2009-07-03 GO:0017129 triglyceride binding Deleted DEFINITION Interacting selectively with any triester of glycerol.
2009-07-03 GO:0070653 high-density lipoprotein particle receptor binding Deleted DEFINITION Interacting selectively with a high-density lipoprotein receptor.
2009-07-03 GO:0032555 purine ribonucleotide binding Deleted DEFINITION Interacting selectively with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
2009-07-03 GO:0005523 tropomyosin binding Deleted DEFINITION Interacting selectively with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.
2009-07-03 GO:0030544 Hsp70 protein binding Deleted DEFINITION Interacting selectively with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
2009-07-03 GO:0048028 galacturonan binding Deleted DEFINITION Interacting selectively with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.
2009-07-03 GO:0005145 interleukin-14 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-14 receptor.
2009-07-03 GO:0050897 cobalt ion binding Deleted DEFINITION Interacting selectively with a cobalt (Co) ion.
2009-07-03 GO:0032266 phosphatidylinositol-3-phosphate binding Deleted DEFINITION Interacting selectively with phosphatidylinositol 3-phosphate, a phosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0031893 vasopressin receptor binding Deleted DEFINITION Interacting selectively with a vasopressin receptor.
2009-07-03 GO:0050699 WW domain binding Added DEFINITION Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
2009-07-03 GO:0050700 CARD domain binding Added DEFINITION Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.
2009-07-03 GO:0050811 GABA receptor binding Added DEFINITION Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
2009-07-03 GO:0050997 quaternary ammonium group binding Added DEFINITION Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
2009-07-03 GO:0051010 microtubule plus-end binding Added DEFINITION Interacting selectively and non-covalently with the plus end of a microtubule.
2009-07-03 GO:0051015 actin filament binding Added DEFINITION Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2009-07-03 GO:0051019 mitogen-activated protein kinase binding Added DEFINITION Interacting selectively and non-covalently with a mitogen-activated protein kinase.
2009-07-03 GO:0051416 myotilin binding Added DEFINITION Interacting selectively and non-covalently with myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C.
2009-07-03 GO:0051433 BH2 domain binding Added DEFINITION Interacting selectively and non-covalently with the BH2 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.
2009-07-03 GO:0051535 syntaxin-5 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-5.
2009-07-03 GO:0051577 MyoD binding Added DEFINITION Interacting selectively and non-covalently with the muscle regulatory factor MyoD.
2009-07-03 GO:0051916 granulocyte colony-stimulating factor binding Added DEFINITION Interacting selectively and non-covalently with granulocyte colony-stimulating factor, G-CSF.
2009-07-03 GO:0051959 dynein light intermediate chain binding Added DEFINITION Interacting selectively and non-covalently with a light intermediate chain of the dynein complex.
2009-07-03 GO:0055100 adiponectin binding Added DEFINITION Interacting selectively and non-covalently with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.
2009-07-03 GO:0070080 titin Z domain binding Added DEFINITION Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
2009-07-03 GO:0001852 complement component iC3b binding Deleted DEFINITION Interacting selectively with the iC3b product of the complement cascade.
2009-07-03 GO:0005522 profilin binding Deleted DEFINITION Interacting selectively with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.
2009-07-03 GO:0030622 U4atac snRNA binding Deleted DEFINITION Interacting selectively with the U4atac small nuclear RNA (U4atac snRNA).
2009-07-03 GO:0017046 peptide hormone binding Deleted DEFINITION Interacting selectively with any peptide with hormonal activity in animals.
2009-07-03 GO:0050839 cell adhesion molecule binding Deleted DEFINITION Interacting selectively with a cell adhesion molecule.
2009-07-03 GO:0034513 box H/ACA snoRNA binding Deleted DEFINITION Interacting selectively with box H/ACA small nucleolar RNA.
2009-07-03 GO:0070539 linoleic acid binding Deleted DEFINITION Interacting selectively with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.
2009-07-03 GO:0003676 nucleic acid binding Deleted DEFINITION Interacting selectively with any nucleic acid.
2009-07-03 GO:0019003 GDP binding Deleted DEFINITION Interacting selectively with GDP, guanosine 5'-diphosphate.
2009-07-03 GO:0051416 myotilin binding Deleted DEFINITION Interacting selectively with myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C.
2009-07-03 GO:0009367 prepilin peptidase complex Deleted DEFINITION An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group.
2009-07-03 GO:0031804 type 7 metabotropic glutamate receptor binding Deleted DEFINITION Interacting selectively with a type 7 metabotropic glutamate receptor.
2009-07-03 GO:0046876 3,4-didehydroretinal binding Deleted DEFINITION Interacting selectively with 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).
2009-07-03 GO:0043014 alpha-tubulin binding Deleted DEFINITION Interacting selectively with the microtubule constituent protein alpha-tubulin.
2009-07-03 GO:0042277 peptide binding Deleted DEFINITION Interacting selectively with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
2009-07-03 GO:0032547 purine deoxyribonucleoside binding Deleted DEFINITION Interacting selectively with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.
2009-07-03 GO:0033149 FFAT motif binding Deleted DEFINITION Interacting selectively with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.
2009-07-03 GO:0000339 RNA cap binding Deleted DEFINITION Interacting selectively with a 7-methylguanosine (m7G) moiety or derivative located at the 5' end of an RNA molecule.
2009-07-03 GO:0051577 MyoD binding Deleted DEFINITION Interacting selectively with the muscle regulatory factor MyoD.
2009-07-03 GO:0005102 receptor binding Deleted DEFINITION Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2009-07-03 GO:0043121 neurotrophin binding Deleted DEFINITION Interacting selectively with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth.
2009-07-03 GO:0031796 type 1 metabotropic GABA receptor binding Deleted DEFINITION Interacting selectively with a type 1 metabotropic GABA receptor.
2009-07-03 GO:0070362 mitochondrial heavy strand promoter anti-sense binding Deleted DEFINITION Interacting selectively with the anti-sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA.
2009-07-03 GO:0017076 purine nucleotide binding Deleted DEFINITION Interacting selectively with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.
2009-07-03 GO:0045523 interleukin-27 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-27 receptor.
2009-07-03 GO:0003682 chromatin binding Deleted DEFINITION Interacting selectively with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase.
2009-07-03 GO:0032051 clathrin light chain binding Deleted DEFINITION Interacting selectively with a clathrin light chain.
2009-07-03 GO:0030553 cGMP binding Deleted DEFINITION Interacting selectively with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
2009-07-03 GO:0043199 sulfate binding Deleted DEFINITION Interacting selectively with sulfate (SO42-), a negatively charged small molecule.
2009-07-03 GO:0032027 myosin light chain binding Deleted DEFINITION Interacting selectively with a light chain of a myosin complex.
2009-07-03 GO:0031491 nucleosome binding Deleted DEFINITION Interacting selectively with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
2009-07-03 GO:0032559 adenyl ribonucleotide binding Deleted DEFINITION Interacting selectively with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
2009-07-03 GO:0048038 quinone binding Deleted DEFINITION Interacting selectively with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
2009-07-03 GO:0031883 taste receptor binding Deleted DEFINITION Interacting selectively with a taste receptor.
2009-07-03 GO:0030984 kininogen binding Deleted DEFINITION Interacting selectively with a kininogen, any of a group of plasma proteins that are kinin precursors.
2009-07-03 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding Deleted DEFINITION Interacting selectively with phosphatidylinositol-4,5-bisphosphate, a diphosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0070324 thyroid hormone binding Added DEFINITION Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
2009-07-03 GO:0070336 flap-structured DNA binding Added DEFINITION Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.
2009-07-03 GO:0070403 NAD+ binding Added DEFINITION Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
2009-07-03 GO:0070405 ammonium ion binding Added DEFINITION Interacting selectively and non-covalently with ammonium ions (NH4+).
2009-07-03 GO:0070644 vitamin D response element binding Added DEFINITION Interacting selectively and non-covalently with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
2009-07-03 GO:0070700 BMP receptor binding Added DEFINITION Interacting selectively and non-covalently with a BMP receptor.
2009-07-03 GO:0070773 protein-N-terminal glutamine amidohydrolase activity Added DEFINITION Catalysis of the deamidation of an N-terminal glutamin residue of a protein.
2009-07-03 GO:0000035 acyl binding Added DEFINITION Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
2009-07-03 GO:0000182 rDNA binding Added DEFINITION Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA.
2009-07-03 GO:0000287 magnesium ion binding Added DEFINITION Interacting selectively and non-covalently with magnesium (Mg) ions.
2009-07-03 GO:0000341 RNA trimethylguanosine cap binding Added DEFINITION Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) moiety located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.
2009-07-03 GO:0000400 four-way junction DNA binding Added DEFINITION Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
2009-07-03 GO:0000496 base pairing Added DEFINITION Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target nucleic acid molecule.
2009-07-03 GO:0001530 lipopolysaccharide binding Added DEFINITION Interacting selectively and non-covalently with lipopolysaccharide.
2009-07-03 GO:0001531 interleukin-21 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-21 receptor.
2009-07-03 GO:0001540 beta-amyloid binding Added DEFINITION Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor.
2009-07-03 GO:0001664 G-protein coupled receptor binding Added DEFINITION Interacting selectively and non-covalently with a G-protein-coupled receptor.
2009-07-03 GO:0001854 complement component C3d binding Added DEFINITION Interacting selectively and non-covalently with the C3d product of the complement cascade.
2009-07-03 GO:0001871 pattern binding Added DEFINITION Interacting selectively and non-covalently with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan.
2009-07-03 GO:0001872 (1->3)-beta-D-glucan binding Added DEFINITION Interacting selectively and non-covalently with zymosan.
2009-07-03 GO:0001972 retinoic acid binding Added DEFINITION Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
2009-07-03 GO:0002046 opsin binding Added DEFINITION Interacting selectively and non-covalently with an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
2009-07-03 GO:0002112 interleukin-33 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-33 receptor.
2009-07-03 GO:0003691 double-stranded telomeric DNA binding Added DEFINITION Interacting selectively and non-covalently with double-stranded telomere-associated DNA.
2009-07-03 GO:0003692 left-handed Z-DNA binding Added DEFINITION Interacting selectively and non-covalently with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.
2009-07-03 GO:0003695 random coil DNA binding Added DEFINITION Interacting selectively and non-covalently with DNA in a random coil configuration.
2009-07-03 GO:0003723 RNA binding Added DEFINITION Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2009-07-03 GO:0003779 actin binding Added DEFINITION Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2009-07-03 GO:0003823 antigen binding Added DEFINITION Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
2009-07-03 GO:0005122 torso binding Added DEFINITION Interacting selectively and non-covalently with the torso (tor) protein, a receptor tyrosine kinase.
2009-07-03 GO:0005134 interleukin-2 receptor binding Added DEFINITION Interacting selectively and non-covalently with the interleukin-2 receptor.
2009-07-03 GO:0005147 oncostatin-M receptor binding Added DEFINITION Interacting selectively and non-covalently with the oncostatin-M receptor.
2009-07-03 GO:0005154 epidermal growth factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the epidermal growth factor receptor.
2009-07-03 GO:0019960 C-X3-C chemokine binding Deleted DEFINITION Interacting selectively with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.
2009-07-03 GO:0032546 deoxyribonucleoside binding Deleted DEFINITION Interacting selectively with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.
2009-07-03 GO:0031774 leukotriene receptor binding Added DEFINITION Interacting selectively and non-covalently with a leukotriene receptor.
2009-07-03 GO:0031775 lutropin-choriogonadotropic hormone receptor binding Added DEFINITION Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor.
2009-07-03 GO:0010736 serum response element binding Deleted DEFINITION Interacting selectively with the serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
2009-07-03 GO:0042498 diacyl lipopeptide binding Deleted DEFINITION Interacting selectively with any conjugated, water-soluble protein in which the nonprotein moiety consists of a two acyl groups.
2009-07-03 GO:0005142 interleukin-11 receptor binding Deleted DEFINITION Interacting selectively with the interleukin-11 receptor.
2009-07-03 GO:0034988 Fc-gamma receptor I complex binding Deleted DEFINITION Interacting selectively with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.
2009-07-03 GO:0031754 Edg-1 sphingosine 1-phosphate receptor binding Deleted DEFINITION Interacting selectively with an Edg-1 sphingosine 1-phosphate receptor.
2009-07-03 GO:0031891 type 1 vasoactive intestinal polypeptide receptor binding Deleted DEFINITION Interacting selectively with a type 1 vasoactive intestinal polypeptide receptor.
2009-07-03 GO:0032032 myosin I tail binding Deleted DEFINITION Interacting selectively with the tail region of a myosin I heavy chain.
2009-07-03 GO:0030942 endoplasmic reticulum signal peptide binding Deleted DEFINITION Interacting selectively with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum.
2009-07-03 GO:0030977 taurine binding Deleted DEFINITION Interacting selectively with taurine.
2009-07-03 GO:0032034 myosin II head/neck binding Deleted DEFINITION Interacting selectively with the head/neck region of a myosin II heavy chain.
2009-07-03 GO:0005109 frizzled binding Deleted DEFINITION Interacting selectively with the frizzled (fz) receptor.
2009-07-03 GO:0032405 MutLalpha complex binding Deleted DEFINITION Interacting selectively with the mismatch repair complex MutLalpha.
2009-07-03 GO:0030172 troponin C binding Deleted DEFINITION Interacting selectively with troponin C, the calcium-binding subunit of the troponin complex.
2009-07-03 GO:0031752 D5 dopamine receptor binding Deleted DEFINITION Interacting selectively with a D5 dopamine receptor.
2009-07-03 GO:0043183 vascular endothelial growth factor receptor 1 binding Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 1.
2009-07-03 GO:0070180 large ribosomal subunit rRNA binding Deleted DEFINITION Interacting selectively with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
2009-07-03 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding Deleted DEFINITION Interacting selectively with phosphatidylinositol-3,4-bisphosphate, a diphosphorylated derivative of phosphatidylinositol.
2009-07-03 GO:0070080 titin Z domain binding Deleted DEFINITION Interacting selectively with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
2009-07-03 GO:0005070 SH3/SH2 adaptor activity Deleted DEFINITION Interacting selectively and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
2009-07-03 GO:0050998 nitric-oxide synthase binding Deleted DEFINITION Interacting selectively with the enzyme nitric-oxide synthase.
2009-07-03 GO:0008312 7S RNA binding Deleted DEFINITION Interacting selectively with 7S RNA, the RNA component of the signal recognition particle (SRP).
2009-07-03 GO:0031881 type 4 somatostatin receptor binding Deleted DEFINITION Interacting selectively with a type 4 somatostatin receptor.
2009-07-03 GO:0005497 androgen binding Deleted DEFINITION Interacting selectively with any androgen, male sex hormones.
2009-07-03 GO:0031402 sodium ion binding Deleted DEFINITION Interacting selectively with sodium ions (Na+).
2009-07-03 GO:0005171 hepatocyte growth factor receptor binding Added DEFINITION Interacting selectively and non-covalently with the hepatocyte growth factor receptor.
2009-07-03 GO:0005499 vitamin D binding Added DEFINITION Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
2009-07-03 GO:0005506 iron ion binding Added DEFINITION Interacting selectively and non-covalently with iron (Fe) ions.
2009-07-03 GO:0005527 macrolide binding Added DEFINITION Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.
2009-07-03 GO:0008262 importin-alpha export receptor activity Added DEFINITION Interacting selectively and non-covalently with importin-alpha to mediate its transfer through the nuclear pore to the cytoplasm.
2009-07-03 GO:0008317 gurken receptor binding Added DEFINITION Interacting selectively and non-covalently with the gurken growth factor receptor.
2009-07-03 GO:0008368 Gram-negative bacterial binding Added DEFINITION Interacting selectively and non-covalently with any part of a Gram-negative bacterial cell.
2009-07-03 GO:0008430 selenium binding Added DEFINITION Interacting selectively and non-covalently with selenium (Se).
2009-07-03 GO:0009374 biotin binding Added DEFINITION Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2009-07-03 GO:0010013 N-1-naphthylphthalamic acid binding Added DEFINITION Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor.
2009-07-03 GO:0010331 gibberellin binding Added DEFINITION Interacting selectively and non-covalently with gibberellins, plant hormones that regulate aspects of plant growth.
2009-07-03 GO:0016151 nickel cation binding Added DEFINITION Interacting selectively and non-covalently with nickel (Ni) ions.
2009-07-03 GO:0016208 AMP binding Added DEFINITION Interacting selectively and non-covalently with AMP, adenosine monophosphate.
2009-07-03 GO:0016595 glutamate binding Added DEFINITION Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.
2009-07-03 GO:0017075 syntaxin-1 binding Added DEFINITION Interacting selectively and non-covalently with the SNAP receptor syntaxin-1.
2009-07-03 GO:0017134 fibroblast growth factor binding Added DEFINITION Interacting selectively and non-covalently with fibroblast growth factor.
2009-07-03 GO:0017137 Rab GTPase binding Added DEFINITION Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
2009-07-03 GO:0019002 GMP binding Added DEFINITION Interacting selectively and non-covalently with GMP, guanosine monophosphate.
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