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GO Term History: Displaying 229 audit records for all terms for the date 2009-06-26

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added TERM negative regulation of interleukin-35-mediated signaling pathway
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added TERM positive regulation of interleukin-35-mediated signaling pathway
2009-06-26 GO:0070761 pre-snoRNP complex Added TERM pre-snoRNP complex
2009-06-26 GO:0004022 alcohol dehydrogenase (NAD) activity Updated TERM alcohol dehydrogenase (NAD) activity
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Updated TERM DNA methylation on cytosine within a CHH sequence
2009-06-26 GO:0000172 ribonuclease MRP complex Added DEFINITION A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
2009-06-26 GO:0017087 mitochondrial processing peptidase complex Added DEFINITION A protein complex that consists of a catalytic alpha subunit (alpha-MPP) and a regulatory beta subunits (beta-MPP), and catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.
2009-06-26 GO:0017090 meprin A complex Added DEFINITION A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0070753 interleukin-35 production Added DEFINITION The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added DEFINITION Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
2009-06-26 GO:0070761 pre-snoRNP complex Added DEFINITION A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.
2009-06-26 GO:0043514 interleukin-12 complex Added DEFINITION A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.
2009-06-26 GO:0070743 interleukin-23 complex Added DEFINITION A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.
2009-06-26 GO:0009368 endopeptidase Clp complex Added DEFINITION A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.
2009-06-26 GO:0070747 interleukin-35 receptor activity Added DEFINITION Combining with interleukin-35 to initiate a change in cell activity.
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0005956 protein kinase CK2 complex Added DEFINITION A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein.
2009-06-26 GO:0070746 interleukin-35 binding Added DEFINITION Interacting selectively with interleukin-35.
2009-06-26 GO:0070748 interleukin-35 receptor binding Added DEFINITION Interacting selectively with the interleukin-35 receptor.
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.
2009-06-26 GO:0070742 C2H2 zinc finger domain binding Added DEFINITION Interacting selectively with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
2009-06-26 GO:0070744 interleukin-27 complex Added DEFINITION A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
2009-06-26 GO:0070745 interleukin-35 complex Added DEFINITION A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added DEFINITION Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor.
2009-06-26 GO:0070754 regulation of interleukin-35 production Added DEFINITION Any process that modulates the frequency, rate, or extent of interleukin-35 production.
2009-06-26 GO:0005787 signal peptidase complex Added DEFINITION A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.
2009-06-26 GO:0008303 caspase complex Added DEFINITION A protein complex that is located in the cytosol and acts as a cysteine-type endopeptidase are involved in apoptosis; the peptidase activity has specificity for the hydrolysis of aspartyl bonds.
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Added DEFINITION The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0070746 interleukin-35 binding Added TERM interleukin-35 binding
2009-06-26 GO:0070747 interleukin-35 receptor activity Added TERM interleukin-35 receptor activity
2009-06-26 GO:0070748 interleukin-35 receptor binding Added TERM interleukin-35 receptor binding
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added TERM interleukin-35 biosynthetic process
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added TERM regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added TERM negative regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070742 C2H2 zinc finger domain binding Added TERM C2H2 zinc finger domain binding
2009-06-26 GO:0070743 interleukin-23 complex Added TERM interleukin-23 complex
2009-06-26 GO:0070744 interleukin-27 complex Added TERM interleukin-27 complex
2009-06-26 GO:0070745 interleukin-35 complex Added TERM interleukin-35 complex
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added TERM positive regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070753 interleukin-35 production Added TERM interleukin-35 production
2009-06-26 GO:0070754 regulation of interleukin-35 production Added TERM regulation of interleukin-35 production
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added TERM negative regulation of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added TERM positive regulation of interleukin-35 production
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added TERM interleukin-35-mediated signaling pathway
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added TERM regulation of interleukin-35-mediated signaling pathway
2009-06-26 GO:0017090 meprin A complex Deleted DEFINITION An enzyme complex that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.
2009-06-26 GO:0017087 mitochondrial processing peptidase complex Deleted DEFINITION This enzyme complex catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Deleted DEFINITION The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNN sequence in a DNA molecule. N stands for any nucleotide.
2009-06-26 GO:0005956 protein kinase CK2 complex Deleted DEFINITION A protein complex that possesses protein serine/threonine kinase activity, and is found in nearly every subcellular compartment. Protein kinase CK2 complexes are usually tetramers of two alpha and two beta subunits, and can phosphorylate many protein substrates in addition to casein.
2009-06-26 GO:0005787 signal peptidase complex Deleted DEFINITION A multi subunit protease complex located in the endoplasmic reticulum membrane that cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.
2009-06-26 GO:0005732 small nucleolar ribonucleoprotein complex Deleted DEFINITION A complex composed of RNA of a small nucleolar RNA (snoRNA) and protein, found in eukaryotic cells. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2009-06-26 GO:0009368 endopeptidase Clp complex Deleted DEFINITION An enzymatically active or inactive multimeric complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits.
2009-06-26 GO:0000172 ribonuclease MRP complex Deleted DEFINITION A ribonucleoprotein complex that cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
2009-06-26 GO:0043514 interleukin-12 complex Deleted DEFINITION A protein complex that is composed of an interleukin-12 alpha and an interleukin-12 beta subunit and is secreted into the extracellular space.
2009-06-26 GO:0008303 caspase complex Deleted DEFINITION A cytosolic endopeptidase with specificity for the hydrolysis of aspartyl bonds. Caspases are involved in apoptosis.
2009-06-26 GO:0005732 small nucleolar ribonucleoprotein complex Added DEFINITION A ribonucleoprotein complex that contains a small nucleolar RNA (snoRNA) and associated proteins, and is found in eukaryotic cells. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added DEFINITION A series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added DEFINITION Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM up-regulation of interleukin-35 production
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 synthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of IL-35 biosynthetic process
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM negative regulation of IL-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM up regulation of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM upregulation of interleukin-35 production
2009-06-26 GO:0004022 alcohol dehydrogenase (NAD) activity Added SYNONYM alcohol dehydrogenase activity
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM IL12B
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM p35
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM p28
2009-06-26 GO:0070748 interleukin-35 receptor binding Added SYNONYM IL-35
2009-06-26 GO:0070748 interleukin-35 receptor binding Added SYNONYM interleukin-35 receptor ligand
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of IL-35 biosynthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 anabolism
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM activation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 anabolism
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM down regulation of interleukin-35 production
2009-06-26 GO:0070106 interleukin-27-mediated signaling pathway Deleted SYNONYM IL-27-mediated signaling pathway
2009-06-26 GO:0070107 regulation of interleukin-27-mediated signaling pathway Deleted SYNONYM regulation of IL27RA/IL6ST signaling pathway
2009-06-26 GO:0004022 alcohol dehydrogenase (NAD) activity Deleted SYNONYM alcohol dehydrogenase (NAD) activity
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM IL23A
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM p40
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 formation
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 biosynthesis
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM positive regulation of IL-35 production
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM EBI3
2009-06-26 GO:0070746 interleukin-35 binding Added SYNONYM IL-35 binding
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 biosynthesis
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of IL-35 biosynthesis
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 formation
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM down-regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 biosynthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 synthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM stimulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM up regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070753 interleukin-35 production Added SYNONYM IL-35 production
2009-06-26 GO:0070754 regulation of interleukin-35 production Added SYNONYM regulation of IL-35 production
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM down-regulation of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM activation of interleukin-35 production
2009-06-26 GO:0070761 pre-snoRNP complex Added SYNONYM pre-small nucleolar ribonucleoprotein complex
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM p19
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM EBI3
2009-06-26 GO:0070747 interleukin-35 receptor activity Added SYNONYM IL-35R
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM IL-35 biosynthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM downregulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 formation
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM downregulation of interleukin-35 production
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added SYNONYM interleukin-35-mediated signalling pathway
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added SYNONYM negative regulation of interleukin-35-mediated signalling pathway
2009-06-26 GO:0070106 interleukin-27-mediated signaling pathway Added SYNONYM IL-27-mediated signaling pathway
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM IL-27 complex
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM p35
2009-06-26 GO:0070747 interleukin-35 receptor activity Added SYNONYM IL-35 receptor activity
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 synthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM up-regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added SYNONYM negative regulation of IL-35-mediated signaling pathway
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added SYNONYM positive regulation of IL-35-mediated signaling pathway
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Added SYNONYM cytosine methylation within a CHH sequence
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM IL12A
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM IL-23 complex
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM IL12A
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 biosynthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM down regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 formation
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of IL-35 biosynthesis
2009-06-26 GO:0006716 juvenile hormone metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM p40
2009-06-26 GO:0070107 regulation of interleukin-27-mediated signaling pathway Added SYNONYM regulation of IL27RA/IL6ST signaling pathway
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM IL12B
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM IL27
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 anabolism
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added SYNONYM regulation of IL-35-mediated signaling pathway
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Added SYNONYM DNA methylation on cytosine within a CNN sequence
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM IL-35 complex
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM IL-35 biosynthetic process
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of IL-35 biosynthetic process
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 anabolism
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 synthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM inhibition of interleukin-35 biosynthetic process
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of IL-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM upregulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM inhibition of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM stimulation of interleukin-35 production
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added SYNONYM IL-35-mediated signaling pathway
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added SYNONYM regulation of interleukin-35-mediated signalling pathway
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added SYNONYM positive regulation of interleukin-35-mediated signalling pathway
2009-06-26 GO:0006401 RNA catabolic process Deleted RELATION is a GO:0043285 (biopolymer catabolic process)
2009-06-26 GO:0006308 DNA catabolic process Deleted RELATION is a GO:0043285 (biopolymer catabolic process)
2009-06-26 GO:0006999 nuclear pore organization Deleted RELATION is a GO:0043933 (macromolecular complex subunit organization)
2009-06-26 GO:0008207 C21-steroid hormone metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008209 androgen metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008210 estrogen metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008211 glucocorticoid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008212 mineralocorticoid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0009252 peptidoglycan biosynthetic process Deleted RELATION is a GO:0016051 (carbohydrate biosynthetic process)
2009-06-26 GO:0017180 peptidyl-diphthine biosynthetic process from peptidyl-histidine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0019680 L-methylmalonyl-CoA biosynthetic process Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0009690 cytokinin metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0009692 ethylene metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0009755 hormone-mediated signaling pathway Deleted RELATION is a GO:0009725 (response to hormone)
2009-06-26 GO:0010384 cell wall proteoglycan metabolic process Deleted RELATION is a GO:0044036 (cell wall macromolecule metabolic process)
2009-06-26 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage Deleted RELATION is a GO:0009411 (response to UV)
2009-06-26 GO:0034619 cellular chaperone-mediated protein complex assembly Deleted RELATION is a GO:0043623 (cellular protein complex assembly)
2009-06-26 GO:0019879 peptidyl-thyronine biosynthetic process from peptidyl-tyrosine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0030186 melatonin metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0031161 phosphatidylinositol catabolic process Deleted RELATION is a GO:0009056 (catabolic process)
2009-06-26 GO:0031034 myosin filament assembly Deleted RELATION is a GO:0006461 (protein complex assembly)
2009-06-26 GO:0018250 peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0051383 kinetochore organization Deleted RELATION is a GO:0043933 (macromolecular complex subunit organization)
2009-06-26 GO:0034728 nucleosome organization Deleted RELATION is a GO:0043933 (macromolecular complex subunit organization)
2009-06-26 GO:0042572 retinol metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0042573 retinoic acid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0042403 thyroid hormone metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0042744 hydrogen peroxide catabolic process Deleted RELATION is a GO:0042542 (response to hydrogen peroxide)
2009-06-26 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress Deleted RELATION is a GO:0006979 (response to oxidative stress)
2009-06-26 GO:0043556 regulation of translation in response to oxidative stress Deleted RELATION is a GO:0006979 (response to oxidative stress)
2009-06-26 GO:0045455 ecdysteroid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0046835 carbohydrate phosphorylation Deleted RELATION is a GO:0005975 (carbohydrate metabolic process)
2009-06-26 GO:0046838 phosphorylated carbohydrate dephosphorylation Deleted RELATION is a GO:0005975 (carbohydrate metabolic process)
2009-06-26 GO:0046879 hormone secretion Deleted RELATION is a GO:0046903 (secretion)
2009-06-26 GO:0051131 chaperone-mediated protein complex assembly Deleted RELATION is a GO:0006461 (protein complex assembly)
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0070750 (regulation of interleukin-35 biosynthetic process)
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added RELATION positively regulates GO:0070749 (interleukin-35 biosynthetic process)
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0042108 (positive regulation of cytokine biosynthetic process)
2009-06-26 GO:0070753 interleukin-35 production Added RELATION is a GO:0001816 (cytokine production)
2009-06-26 GO:0070754 regulation of interleukin-35 production Added RELATION regulates GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070754 regulation of interleukin-35 production Added RELATION is a GO:0001817 (regulation of cytokine production)
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added RELATION is a GO:0070754 (regulation of interleukin-35 production)
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added RELATION negatively regulates GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added RELATION is a GO:0001818 (negative regulation of cytokine production)
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added RELATION is a GO:0070754 (regulation of interleukin-35 production)
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added RELATION positively regulates GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added RELATION is a GO:0001819 (positive regulation of cytokine production)
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added RELATION positively regulates GO:0070757 (interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added RELATION regulates GO:0070757 (interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0001959 (regulation of cytokine-mediated signaling pathway)
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0070758 (regulation of interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added RELATION negatively regulates GO:0070757 (interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0001960 (negative regulation of cytokine-mediated signaling pathway)
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0070758 (regulation of interleukin-35-mediated signaling pathway)
2009-06-26 GO:0060751 branch elongation involved in mammary gland duct branching Deleted RELATION part of GO:0060603 (mammary gland duct morphogenesis)
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0001961 (positive regulation of cytokine-mediated signaling pathway)
2009-06-26 GO:0070761 pre-snoRNP complex Added RELATION is a GO:0030529 (ribonucleoprotein complex)
2009-06-26 GO:0070742 C2H2 zinc finger domain binding Added RELATION is a GO:0019904 (protein domain specific binding)
2009-06-26 GO:0070743 interleukin-23 complex Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 GO:0070743 interleukin-23 complex Added RELATION is a GO:0043234 (protein complex)
2009-06-26 GO:0070743 interleukin-23 complex Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 GO:0070744 interleukin-27 complex Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 GO:0070744 interleukin-27 complex Added RELATION is a GO:0043234 (protein complex)
2009-06-26 GO:0070744 interleukin-27 complex Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 GO:0070745 interleukin-35 complex Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 GO:0070745 interleukin-35 complex Added RELATION is a GO:0043234 (protein complex)
2009-06-26 GO:0070745 interleukin-35 complex Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 GO:0070746 interleukin-35 binding Added RELATION is a GO:0019955 (cytokine binding)
2009-06-26 GO:0070747 interleukin-35 receptor activity Added RELATION is a GO:0070746 (interleukin-35 binding)
2009-06-26 GO:0070747 interleukin-35 receptor activity Added RELATION is a GO:0004896 (cytokine receptor activity)
2009-06-26 GO:0070748 interleukin-35 receptor binding Added RELATION is a GO:0005102 (receptor binding)
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added RELATION part of GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added RELATION is a GO:0042089 (cytokine biosynthetic process)
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0070754 (regulation of interleukin-35 production)
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added RELATION regulates GO:0070749 (interleukin-35 biosynthetic process)
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0042035 (regulation of cytokine biosynthetic process)
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0070750 (regulation of interleukin-35 biosynthetic process)
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added RELATION negatively regulates GO:0070749 (interleukin-35 biosynthetic process)
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0042036 (negative regulation of cytokine biosynthetic process)

Terms

Timestamp GO ID GO Term Name Action Category Detail
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added TERM negative regulation of interleukin-35-mediated signaling pathway
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added TERM positive regulation of interleukin-35-mediated signaling pathway
2009-06-26 GO:0070761 pre-snoRNP complex Added TERM pre-snoRNP complex
2009-06-26 GO:0004022 alcohol dehydrogenase (NAD) activity Updated TERM alcohol dehydrogenase (NAD) activity
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Updated TERM DNA methylation on cytosine within a CHH sequence
2009-06-26 GO:0070746 interleukin-35 binding Added TERM interleukin-35 binding
2009-06-26 GO:0070747 interleukin-35 receptor activity Added TERM interleukin-35 receptor activity
2009-06-26 GO:0070748 interleukin-35 receptor binding Added TERM interleukin-35 receptor binding
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added TERM interleukin-35 biosynthetic process
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added TERM regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added TERM negative regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070742 C2H2 zinc finger domain binding Added TERM C2H2 zinc finger domain binding
2009-06-26 GO:0070743 interleukin-23 complex Added TERM interleukin-23 complex
2009-06-26 GO:0070744 interleukin-27 complex Added TERM interleukin-27 complex
2009-06-26 GO:0070745 interleukin-35 complex Added TERM interleukin-35 complex
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added TERM positive regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070753 interleukin-35 production Added TERM interleukin-35 production
2009-06-26 GO:0070754 regulation of interleukin-35 production Added TERM regulation of interleukin-35 production
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added TERM negative regulation of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added TERM positive regulation of interleukin-35 production
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added TERM interleukin-35-mediated signaling pathway
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added TERM regulation of interleukin-35-mediated signaling pathway

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2009-06-26 GO:0000172 ribonuclease MRP complex Added DEFINITION A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
2009-06-26 GO:0017087 mitochondrial processing peptidase complex Added DEFINITION A protein complex that consists of a catalytic alpha subunit (alpha-MPP) and a regulatory beta subunits (beta-MPP), and catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.
2009-06-26 GO:0017090 meprin A complex Added DEFINITION A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0070753 interleukin-35 production Added DEFINITION The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added DEFINITION Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
2009-06-26 GO:0070761 pre-snoRNP complex Added DEFINITION A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.
2009-06-26 GO:0043514 interleukin-12 complex Added DEFINITION A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.
2009-06-26 GO:0070743 interleukin-23 complex Added DEFINITION A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.
2009-06-26 GO:0009368 endopeptidase Clp complex Added DEFINITION A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.
2009-06-26 GO:0070747 interleukin-35 receptor activity Added DEFINITION Combining with interleukin-35 to initiate a change in cell activity.
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0005956 protein kinase CK2 complex Added DEFINITION A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein.
2009-06-26 GO:0070746 interleukin-35 binding Added DEFINITION Interacting selectively with interleukin-35.
2009-06-26 GO:0070748 interleukin-35 receptor binding Added DEFINITION Interacting selectively with the interleukin-35 receptor.
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.
2009-06-26 GO:0070742 C2H2 zinc finger domain binding Added DEFINITION Interacting selectively with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
2009-06-26 GO:0070744 interleukin-27 complex Added DEFINITION A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
2009-06-26 GO:0070745 interleukin-35 complex Added DEFINITION A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added DEFINITION Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor.
2009-06-26 GO:0070754 regulation of interleukin-35 production Added DEFINITION Any process that modulates the frequency, rate, or extent of interleukin-35 production.
2009-06-26 GO:0005787 signal peptidase complex Added DEFINITION A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.
2009-06-26 GO:0008303 caspase complex Added DEFINITION A protein complex that is located in the cytosol and acts as a cysteine-type endopeptidase are involved in apoptosis; the peptidase activity has specificity for the hydrolysis of aspartyl bonds.
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Added DEFINITION The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0017090 meprin A complex Deleted DEFINITION An enzyme complex that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.
2009-06-26 GO:0017087 mitochondrial processing peptidase complex Deleted DEFINITION This enzyme complex catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Deleted DEFINITION The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNN sequence in a DNA molecule. N stands for any nucleotide.
2009-06-26 GO:0005956 protein kinase CK2 complex Deleted DEFINITION A protein complex that possesses protein serine/threonine kinase activity, and is found in nearly every subcellular compartment. Protein kinase CK2 complexes are usually tetramers of two alpha and two beta subunits, and can phosphorylate many protein substrates in addition to casein.
2009-06-26 GO:0005787 signal peptidase complex Deleted DEFINITION A multi subunit protease complex located in the endoplasmic reticulum membrane that cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.
2009-06-26 GO:0005732 small nucleolar ribonucleoprotein complex Deleted DEFINITION A complex composed of RNA of a small nucleolar RNA (snoRNA) and protein, found in eukaryotic cells. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2009-06-26 GO:0009368 endopeptidase Clp complex Deleted DEFINITION An enzymatically active or inactive multimeric complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits.
2009-06-26 GO:0000172 ribonuclease MRP complex Deleted DEFINITION A ribonucleoprotein complex that cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
2009-06-26 GO:0043514 interleukin-12 complex Deleted DEFINITION A protein complex that is composed of an interleukin-12 alpha and an interleukin-12 beta subunit and is secreted into the extracellular space.
2009-06-26 GO:0008303 caspase complex Deleted DEFINITION A cytosolic endopeptidase with specificity for the hydrolysis of aspartyl bonds. Caspases are involved in apoptosis.
2009-06-26 GO:0005732 small nucleolar ribonucleoprotein complex Added DEFINITION A ribonucleoprotein complex that contains a small nucleolar RNA (snoRNA) and associated proteins, and is found in eukaryotic cells. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of interleukin-35.
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added DEFINITION A series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added DEFINITION Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM up-regulation of interleukin-35 production
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 synthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of IL-35 biosynthetic process
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM negative regulation of IL-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM up regulation of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM upregulation of interleukin-35 production
2009-06-26 GO:0004022 alcohol dehydrogenase (NAD) activity Added SYNONYM alcohol dehydrogenase activity
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM IL12B
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM p35
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM p28
2009-06-26 GO:0070748 interleukin-35 receptor binding Added SYNONYM IL-35
2009-06-26 GO:0070748 interleukin-35 receptor binding Added SYNONYM interleukin-35 receptor ligand
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of IL-35 biosynthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 anabolism
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM activation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 anabolism
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM down regulation of interleukin-35 production
2009-06-26 GO:0070106 interleukin-27-mediated signaling pathway Deleted SYNONYM IL-27-mediated signaling pathway
2009-06-26 GO:0070107 regulation of interleukin-27-mediated signaling pathway Deleted SYNONYM regulation of IL27RA/IL6ST signaling pathway
2009-06-26 GO:0004022 alcohol dehydrogenase (NAD) activity Deleted SYNONYM alcohol dehydrogenase (NAD) activity
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM IL23A
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM p40
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 formation
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 biosynthesis
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM positive regulation of IL-35 production
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM EBI3
2009-06-26 GO:0070746 interleukin-35 binding Added SYNONYM IL-35 binding
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 biosynthesis
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of IL-35 biosynthesis
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 formation
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM down-regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 biosynthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 synthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM stimulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM up regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070753 interleukin-35 production Added SYNONYM IL-35 production
2009-06-26 GO:0070754 regulation of interleukin-35 production Added SYNONYM regulation of IL-35 production
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM down-regulation of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM activation of interleukin-35 production
2009-06-26 GO:0070761 pre-snoRNP complex Added SYNONYM pre-small nucleolar ribonucleoprotein complex
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM p19
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM EBI3
2009-06-26 GO:0070747 interleukin-35 receptor activity Added SYNONYM IL-35R
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM IL-35 biosynthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM downregulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of interleukin-35 formation
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM downregulation of interleukin-35 production
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added SYNONYM interleukin-35-mediated signalling pathway
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added SYNONYM negative regulation of interleukin-35-mediated signalling pathway
2009-06-26 GO:0070106 interleukin-27-mediated signaling pathway Added SYNONYM IL-27-mediated signaling pathway
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM IL-27 complex
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM p35
2009-06-26 GO:0070747 interleukin-35 receptor activity Added SYNONYM IL-35 receptor activity
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 synthesis
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM up-regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added SYNONYM negative regulation of IL-35-mediated signaling pathway
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added SYNONYM positive regulation of IL-35-mediated signaling pathway
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Added SYNONYM cytosine methylation within a CHH sequence
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM IL12A
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM IL-23 complex
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM IL12A
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 biosynthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM down regulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of interleukin-35 formation
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM positive regulation of IL-35 biosynthesis
2009-06-26 GO:0043514 interleukin-12 complex Added SYNONYM p40
2009-06-26 GO:0070107 regulation of interleukin-27-mediated signaling pathway Added SYNONYM regulation of IL27RA/IL6ST signaling pathway
2009-06-26 GO:0070743 interleukin-23 complex Added SYNONYM IL12B
2009-06-26 GO:0070744 interleukin-27 complex Added SYNONYM IL27
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM interleukin-35 anabolism
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added SYNONYM regulation of IL-35-mediated signaling pathway
2009-06-26 GO:0010426 DNA methylation on cytosine within a CHH sequence Added SYNONYM DNA methylation on cytosine within a CNN sequence
2009-06-26 GO:0070745 interleukin-35 complex Added SYNONYM IL-35 complex
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added SYNONYM IL-35 biosynthetic process
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of IL-35 biosynthetic process
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 anabolism
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added SYNONYM regulation of interleukin-35 synthesis
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM inhibition of interleukin-35 biosynthetic process
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added SYNONYM negative regulation of IL-35 biosynthetic process
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added SYNONYM upregulation of interleukin-35 biosynthetic process
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added SYNONYM inhibition of interleukin-35 production
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added SYNONYM stimulation of interleukin-35 production
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added SYNONYM IL-35-mediated signaling pathway
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added SYNONYM regulation of interleukin-35-mediated signalling pathway
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added SYNONYM positive regulation of interleukin-35-mediated signalling pathway

Relationships

Timestamp GO ID GO Term Name Action Category Detail
2009-06-26 GO:0006716 juvenile hormone metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0006401 RNA catabolic process Deleted RELATION is a GO:0043285 (biopolymer catabolic process)
2009-06-26 GO:0006308 DNA catabolic process Deleted RELATION is a GO:0043285 (biopolymer catabolic process)
2009-06-26 GO:0006999 nuclear pore organization Deleted RELATION is a GO:0043933 (macromolecular complex subunit organization)
2009-06-26 GO:0008207 C21-steroid hormone metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008209 androgen metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008210 estrogen metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008211 glucocorticoid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0008212 mineralocorticoid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0009252 peptidoglycan biosynthetic process Deleted RELATION is a GO:0016051 (carbohydrate biosynthetic process)
2009-06-26 GO:0017180 peptidyl-diphthine biosynthetic process from peptidyl-histidine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0019680 L-methylmalonyl-CoA biosynthetic process Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0009690 cytokinin metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0009692 ethylene metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0009755 hormone-mediated signaling pathway Deleted RELATION is a GO:0009725 (response to hormone)
2009-06-26 GO:0010384 cell wall proteoglycan metabolic process Deleted RELATION is a GO:0044036 (cell wall macromolecule metabolic process)
2009-06-26 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage Deleted RELATION is a GO:0009411 (response to UV)
2009-06-26 GO:0034619 cellular chaperone-mediated protein complex assembly Deleted RELATION is a GO:0043623 (cellular protein complex assembly)
2009-06-26 GO:0019879 peptidyl-thyronine biosynthetic process from peptidyl-tyrosine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0030186 melatonin metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0031161 phosphatidylinositol catabolic process Deleted RELATION is a GO:0009056 (catabolic process)
2009-06-26 GO:0031034 myosin filament assembly Deleted RELATION is a GO:0006461 (protein complex assembly)
2009-06-26 GO:0018250 peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine Deleted RELATION is a GO:0009058 (biosynthetic process)
2009-06-26 GO:0051383 kinetochore organization Deleted RELATION is a GO:0043933 (macromolecular complex subunit organization)
2009-06-26 GO:0034728 nucleosome organization Deleted RELATION is a GO:0043933 (macromolecular complex subunit organization)
2009-06-26 GO:0042572 retinol metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0042573 retinoic acid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0042403 thyroid hormone metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0042744 hydrogen peroxide catabolic process Deleted RELATION is a GO:0042542 (response to hydrogen peroxide)
2009-06-26 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress Deleted RELATION is a GO:0006979 (response to oxidative stress)
2009-06-26 GO:0043556 regulation of translation in response to oxidative stress Deleted RELATION is a GO:0006979 (response to oxidative stress)
2009-06-26 GO:0045455 ecdysteroid metabolic process Deleted RELATION is a GO:0042445 (hormone metabolic process)
2009-06-26 GO:0046835 carbohydrate phosphorylation Deleted RELATION is a GO:0005975 (carbohydrate metabolic process)
2009-06-26 GO:0046838 phosphorylated carbohydrate dephosphorylation Deleted RELATION is a GO:0005975 (carbohydrate metabolic process)
2009-06-26 GO:0046879 hormone secretion Deleted RELATION is a GO:0046903 (secretion)
2009-06-26 GO:0051131 chaperone-mediated protein complex assembly Deleted RELATION is a GO:0006461 (protein complex assembly)
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0070750 (regulation of interleukin-35 biosynthetic process)
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added RELATION positively regulates GO:0070749 (interleukin-35 biosynthetic process)
2009-06-26 GO:0070752 positive regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0042108 (positive regulation of cytokine biosynthetic process)
2009-06-26 GO:0070753 interleukin-35 production Added RELATION is a GO:0001816 (cytokine production)
2009-06-26 GO:0070754 regulation of interleukin-35 production Added RELATION regulates GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070754 regulation of interleukin-35 production Added RELATION is a GO:0001817 (regulation of cytokine production)
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added RELATION is a GO:0070754 (regulation of interleukin-35 production)
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added RELATION negatively regulates GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070755 negative regulation of interleukin-35 production Added RELATION is a GO:0001818 (negative regulation of cytokine production)
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added RELATION is a GO:0070754 (regulation of interleukin-35 production)
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added RELATION positively regulates GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070756 positive regulation of interleukin-35 production Added RELATION is a GO:0001819 (positive regulation of cytokine production)
2009-06-26 GO:0070757 interleukin-35-mediated signaling pathway Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added RELATION positively regulates GO:0070757 (interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added RELATION regulates GO:0070757 (interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070758 regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0001959 (regulation of cytokine-mediated signaling pathway)
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0070758 (regulation of interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added RELATION negatively regulates GO:0070757 (interleukin-35-mediated signaling pathway)
2009-06-26 GO:0070759 negative regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0001960 (negative regulation of cytokine-mediated signaling pathway)
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0070758 (regulation of interleukin-35-mediated signaling pathway)
2009-06-26 GO:0060751 branch elongation involved in mammary gland duct branching Deleted RELATION part of GO:0060603 (mammary gland duct morphogenesis)
2009-06-26 GO:0070760 positive regulation of interleukin-35-mediated signaling pathway Added RELATION is a GO:0001961 (positive regulation of cytokine-mediated signaling pathway)
2009-06-26 GO:0070761 pre-snoRNP complex Added RELATION is a GO:0030529 (ribonucleoprotein complex)
2009-06-26 GO:0070742 C2H2 zinc finger domain binding Added RELATION is a GO:0019904 (protein domain specific binding)
2009-06-26 GO:0070743 interleukin-23 complex Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 GO:0070743 interleukin-23 complex Added RELATION is a GO:0043234 (protein complex)
2009-06-26 GO:0070743 interleukin-23 complex Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 GO:0070744 interleukin-27 complex Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 GO:0070744 interleukin-27 complex Added RELATION is a GO:0043234 (protein complex)
2009-06-26 GO:0070744 interleukin-27 complex Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 GO:0070745 interleukin-35 complex Added RELATION is a GO:0044421 (extracellular region part)
2009-06-26 GO:0070745 interleukin-35 complex Added RELATION is a GO:0043234 (protein complex)
2009-06-26 GO:0070745 interleukin-35 complex Added RELATION part of GO:0005615 (extracellular space)
2009-06-26 GO:0070746 interleukin-35 binding Added RELATION is a GO:0019955 (cytokine binding)
2009-06-26 GO:0070747 interleukin-35 receptor activity Added RELATION is a GO:0070746 (interleukin-35 binding)
2009-06-26 GO:0070747 interleukin-35 receptor activity Added RELATION is a GO:0004896 (cytokine receptor activity)
2009-06-26 GO:0070748 interleukin-35 receptor binding Added RELATION is a GO:0005102 (receptor binding)
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added RELATION part of GO:0070753 (interleukin-35 production)
2009-06-26 GO:0070749 interleukin-35 biosynthetic process Added RELATION is a GO:0042089 (cytokine biosynthetic process)
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0070754 (regulation of interleukin-35 production)
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added RELATION regulates GO:0070749 (interleukin-35 biosynthetic process)
2009-06-26 GO:0070750 regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0042035 (regulation of cytokine biosynthetic process)
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0070750 (regulation of interleukin-35 biosynthetic process)
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added RELATION negatively regulates GO:0070749 (interleukin-35 biosynthetic process)
2009-06-26 GO:0070751 negative regulation of interleukin-35 biosynthetic process Added RELATION is a GO:0042036 (negative regulation of cytokine biosynthetic process)
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