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GO Term History: Displaying 500 audit records for all terms for the date 2008-05-13

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2008-05-13 GO:0006621 protein retention in ER lumen Updated TERM protein retention in ER lumen
2008-05-13 GO:0008326 site-specific DNA-methyltransferase (cytosine-specific) activity Deleted TERM site-specific DNA-methyltransferase (cytosine-specific) activity
2008-05-13 GO:0034433 steroid esterification Added TERM steroid esterification
2008-05-13 GO:0034434 sterol esterification Added TERM sterol esterification
2008-05-13 GO:0034435 cholesterol esterification Added TERM cholesterol esterification
2008-05-13 GO:0034436 glycoprotein transport Added TERM glycoprotein transport
2008-05-13 GO:0034437 glycoprotein transporter activity Added TERM glycoprotein transporter activity
2008-05-13 GO:0034438 lipoprotein amino acid oxidation Added TERM lipoprotein amino acid oxidation
2008-05-13 GO:0034439 lipoprotein lipid oxidation Added TERM lipoprotein lipid oxidation
2008-05-13 GO:0034440 lipid oxidation Added TERM lipid oxidation
2008-05-13 GO:0034441 plasma lipoprotein particle oxidation Added TERM plasma lipoprotein oxidation
2008-05-13 GO:0034442 regulation of lipoprotein oxidation Added TERM regulation of lipoprotein oxidation
2008-05-13 GO:0034443 negative regulation of lipoprotein oxidation Added TERM negative regulation of lipoprotein oxidation
2008-05-13 GO:0034444 regulation of plasma lipoprotein particle oxidation Added TERM regulation of plasma lipoprotein oxidation
2008-05-13 GO:0034445 negative regulation of plasma lipoprotein particle oxidation Added TERM negative regulation of plasma lipoprotein oxidation
2008-05-13 GO:0043899 phosphoserine:homoserine phosphotransferase activity Added TERM phosphoserine:homoserine phosphotransferase activity
2008-05-13 GO:0045053 protein retention in Golgi apparatus Updated TERM protein retention in Golgi apparatus
2008-05-13 GO:0030482 actin cable Added DEFINITION A long bundle of actin filaments, comprising filamentous actin and associated proteins, found in cells.
2008-05-13 GO:0045011 actin cable formation Added DEFINITION The assembly of the long bundles of actin filaments known as actin cables.
2008-05-13 GO:0030478 actin cap Added DEFINITION Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell.
2008-05-13 GO:0005870 actin capping protein of dynactin complex Added DEFINITION A heterodimer consisting of alpha and a beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex.
2008-05-13 GO:0030479 actin cortical patch Added DEFINITION Discrete actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2008-05-13 GO:0000147 actin cortical patch assembly Added DEFINITION Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
2008-05-13 GO:0005503 all-trans retinal binding Added DEFINITION Interacting selectively with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
2008-05-13 GO:0051786 all-trans-retinol 13,14-reductase activity Added DEFINITION Catalysis of the reaction: all-trans-13,14-dihydroretinol + acceptor = all-trans-retinol + reduced acceptor. Note that this reaction has only been observed to occur in the opposite direction.
2008-05-13 GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity Added DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2008-05-13 GO:0047652 allantoate deiminase activity Added DEFINITION Catalysis of the reaction: 2 H2O + 2 allantoate = O2 + 2 CO2 + 2 NH3 + 2 ureidoglycine.
2008-05-13 GO:0015124 allantoate transmembrane transporter activity Added DEFINITION Catalysis of the transfer of allantoate from one side of the membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.
2008-05-13 GO:0015719 allantoate transport Added DEFINITION The directed movement of allantoate into, out of, within or between cells.
2008-05-13 GO:0004037 allantoicase activity Added DEFINITION Catalysis of the reaction: allantoate + H2O = (-)-ureidoglycolate + urea.
2008-05-13 GO:0009442 allantoin assimilation pathway Added DEFINITION The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP.
2008-05-13 GO:0019428 allantoin biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
2008-05-13 GO:0000256 allantoin catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
2008-05-13 GO:0000255 allantoin metabolic process Added DEFINITION The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.
2008-05-13 GO:0047653 allantoin racemase activity Added DEFINITION Catalysis of the reaction: (S)(+)-allantoin = (R)(-)-allantoin.
2008-05-13 GO:0015720 allantoin transport Added DEFINITION The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of, within or between cells.
2008-05-13 GO:0005274 allantoin uptake transmembrane transporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.
2008-05-13 GO:0006838 allantoin/allantoate transport Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0004038 allantoinase activity Added DEFINITION Catalysis of the reaction: allantoin + H2O = allantoate.
2008-05-13 GO:0016086 allatostatin Added DEFINITION OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone.
2008-05-13 GO:0008261 allatostatin receptor activity Added DEFINITION Combining with allatostatin to initiate a change in cell activity.
2008-05-13 GO:0009978 allene oxide synthase activity Added DEFINITION Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.
2008-05-13 GO:0046423 allene-oxide cyclase activity Added DEFINITION Catalysis of the reaction: (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.
2008-05-13 GO:0047654 alliin lyase activity Added DEFINITION Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.
2008-05-13 GO:0004039 allophanate hydrolase activity Added DEFINITION Catalysis of the reaction: urea-1-carboxylate + H2O = 2 CO2 + 2 NH3.
2008-05-13 GO:0008786 allose 6-phosphate isomerase activity Added DEFINITION Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.
2008-05-13 GO:0046366 allose biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0046367 allose catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0008787 allose kinase activity Added DEFINITION Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.
2008-05-13 GO:0019313 allose metabolic process Added DEFINITION The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0015593 allose transmembrane transporter activity Added DEFINITION Catalysis of the transfer of allose from one side of the membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0015754 allose transport Added DEFINITION The directed movement of allose into, out of, within or between cells. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0047655 allyl-alcohol dehydrogenase activity Added DEFINITION Catalysis of the reaction: allyl alcohol + NADP+ = acrolein + NADPH.
2008-05-13 GO:0051411 ALP binding Added DEFINITION Interacting selectively wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band.
2008-05-13 GO:0005658 alpha DNA polymerase:primase complex Added DEFINITION A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.
2008-05-13 GO:0031127 alpha-(1,2)-fucosyltransferase activity Added DEFINITION Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,2)-linkage.
2008-05-13 GO:0046920 alpha-(1->3)-fucosyltransferase activity Added DEFINITION Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,3)-linkage.
2008-05-13 GO:0046921 alpha-(1->6)-fucosyltransferase activity Added DEFINITION Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,6)-linkage.
2008-05-13 GO:0008788 alpha,alpha-phosphotrehalase activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate.
2008-05-13 GO:0004555 alpha,alpha-trehalase activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.
2008-05-13 GO:0033832 alpha,alpha-trehalose phosphorylase (configuration-retaining) activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.
2008-05-13 GO:0047656 alpha,alpha-trehalose phosphorylase activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
2008-05-13 GO:0047260 alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity Added DEFINITION Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.
2008-05-13 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Added DEFINITION Catalysis of the reaction: UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
2008-05-13 GO:0042868 antisense RNA metabolic process Added DEFINITION The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.
2008-05-13 GO:0009300 antisense RNA transcription Added DEFINITION The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
2008-05-13 GO:0045152 antisigma factor binding Added DEFINITION Interacting selectively with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.
2008-05-13 GO:0003800 antiviral response protein activity Added DEFINITION OBSOLETE. A protein involved in an antiviral response.
2008-05-13 GO:0001547 antral ovarian follicle growth Added DEFINITION Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.
2008-05-13 GO:0030121 AP-1 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2008-05-13 GO:0030122 AP-2 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles.
2008-05-13 GO:0030123 AP-3 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2008-05-13 GO:0030124 AP-4 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.
2008-05-13 GO:0030119 AP-type membrane coat adaptor complex Added DEFINITION Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).
2008-05-13 GO:0060182 apelin receptor activity Added DEFINITION Combining with the peptide apelin to initiate a change in cell activity.
2008-05-13 GO:0031704 apelin receptor binding Added DEFINITION Interacting selectively with an apelin receptor.
2008-05-13 GO:0060183 apelin receptor signaling pathway Added DEFINITION The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands.
2008-05-13 GO:0001597 apelin-like receptor Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0019778 Atg12 activating enzyme activity Added DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
2008-05-13 GO:0019792 APG12 hydrolase activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0019777 Atg12 ligase activity Added DEFINITION Catalysis of the covalent attachment of the ubiquitin-like protein APG12 to other proteins.
2008-05-13 GO:0019779 Atg8 activating enzyme Added DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.
2008-05-13 GO:0019776 Atg8 ligase activity Added DEFINITION Catalysis of the covalent attachment of the ubiquitin-like protein APG8 to substrate molecules; phosphatidylethanolamine is a known substrate.
2008-05-13 GO:0019786 Atg8-specific protease activity Added DEFINITION Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
2008-05-13 GO:0046567 aphidicolan-16 beta-ol synthase activity Added DEFINITION Catalysis of the formation of aphidicolan-16 beta-ol from geranylgeranyl diphosphate.
2008-05-13 GO:0020007 apical complex Added DEFINITION Protruding complex at the anterior end of some life cycle stages of all apicomplexan parasites, involved in both the attachment and penetration of the host cell by the parasite.
2008-05-13 GO:0045179 apical cortex Added DEFINITION The region that lies just beneath the plasma membrane on the apical edge of a cell.
2008-05-13 GO:0005928 apical hemi-adherens junction Added DEFINITION An adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle.
2008-05-13 GO:0043297 apical junction assembly Added DEFINITION The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.
2008-05-13 GO:0043296 apical junction complex Added DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2008-05-13 GO:0032579 apical lamina of hyaline layer Added DEFINITION A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.
2008-05-13 GO:0045177 apical part of cell Added DEFINITION The apical region of a cell.
2008-05-13 GO:0016324 apical plasma membrane Added DEFINITION Part of the plasma membrane at the apical end of the cell.
2008-05-13 GO:0045176 apical protein localization Added DEFINITION The processes by which a protein is transported to, or maintained in, apical regions of the cell.
2008-05-13 GO:0016327 apicolateral plasma membrane Added DEFINITION The apical end of the lateral plasma membrane of epithelial cells.
2008-05-13 GO:0020011 apicoplast Added DEFINITION The plastid organelle found in apicomplexans.
2008-05-13 GO:0030754 apigenin 4'-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.
2008-05-13 GO:0033737 1-pyrroline dehydrogenase activity Added DEFINITION Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.
2008-05-13 GO:0047425 1-pyrroline-4-hydroxy-2-carboxylate deaminase activity Added DEFINITION Catalysis of the reaction: H2O + 1-pyrroline-4-hydroxy-2-carboxylate = NH3 + 2,5-dioxopentanoate.
2008-05-13 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H+.
2008-05-13 GO:0050643 10-deacetylbaccatin III 10-O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III.
2008-05-13 GO:0009257 10-formyltetrahydrofolate biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
2008-05-13 GO:0009258 10-formyltetrahydrofolate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
2008-05-13 GO:0009256 10-formyltetrahydrofolate metabolic process Added DEFINITION The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
2008-05-13 GO:0030779 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine.
2008-05-13 GO:0050639 10-hydroxytaxane O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + 10-desacetyltaxuyunnanin C = CoA + taxuyunnanin C.
2008-05-13 GO:0033236 11-beta-hydroxysteroid dehydrogenase (NAD+) activity Added DEFINITION OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.
2008-05-13 GO:0033237 11-beta-hydroxysteroid dehydrogenase (NADP+) activity Added DEFINITION OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.
2008-05-13 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity Added DEFINITION Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+.
2008-05-13 GO:0005502 11-cis retinal binding Added DEFINITION Interacting selectively with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
2008-05-13 GO:0047520 11-cis-retinyl-palmitate hydrolase activity Added DEFINITION Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate.
2008-05-13 GO:0030766 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.
2008-05-13 GO:0047013 cholate 12-alpha dehydrogenase activity Added DEFINITION Catalysis of the reaction: NADP+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate = NADPH + H+ + 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate.
2008-05-13 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-alpha,7-alpha,12-beta-trihydroxy-5-beta-cholanate + NADP+ = 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + NADPH + H+.
2008-05-13 GO:0030780 12-hydroxydihydrochelirubine 12-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-homocysteine + dihydromacarpine.
2008-05-13 GO:0016629 12-oxophytodienoate reductase activity Added DEFINITION Catalysis of the reaction: 8-((1R,2R)-3-oxo-2-((Z)-pent-2-enyl)cyclopentyl)octanoate + NADP+ = (15Z)-12-oxophyto-10,15-dienoate + NADPH.
2008-05-13 GO:0047229 13-hydroxydocosanoate 13-beta-glucosyltransferase activity Added DEFINITION Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.
2008-05-13 GO:0047203 13-hydroxylupinine O-tigloyltransferase activity Added DEFINITION Catalysis of the reaction: 13-hydroxylupinine + (E)-2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyl)oxylupinine + CoA.
2008-05-13 GO:0050617 15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity Added DEFINITION Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
2008-05-13 GO:0047034 15-hydroxyicosatetraenoate dehydrogenase activity Added DEFINITION Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.
2008-05-13 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.
2008-05-13 GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate = NADPH + H+ + (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate.
2008-05-13 GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.
2008-05-13 GO:0047033 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-dienoate.
2008-05-13 GO:0047522 15-oxoprostaglandin 13-oxidase activity Added DEFINITION Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.
2008-05-13 GO:0047455 16-alpha-hydroxyprogesterone dehydratase activity Added DEFINITION Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.
2008-05-13 GO:0047005 16-alpha-hydroxysteroid dehydrogenase activity Added DEFINITION Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.
2008-05-13 GO:0047524 16-hydroxysteroid epimerase activity Added DEFINITION Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.
2008-05-13 GO:0030768 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxy-tabersonine = S-adenosyl-L-homocysteine + deacetoxyvindoline.
2008-05-13 GO:0047442 17-alpha-hydroxyprogesterone aldolase activity Added DEFINITION Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione.
2008-05-13 GO:0047162 17-O-deacetylvindoline O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: 17-O-deacetylvindoline + acetyl-CoA = vindoline + CoA.
2008-05-13 GO:0047311 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity Added DEFINITION Catalysis of the reaction: pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol = L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol.
2008-05-13 GO:0051537 2 iron, 2 sulfur cluster binding Added DEFINITION Interacting selectively with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
2008-05-13 GO:0008663 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity Added DEFINITION Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
2008-05-13 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity Added DEFINITION Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.
2008-05-13 GO:0019361 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
2008-05-13 GO:0046432 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process Added DEFINITION The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
2008-05-13 GO:0001730 2'-5'-oligoadenylate synthetase activity Added DEFINITION Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. Requires binding of double-stranded RNA.
2008-05-13 GO:0018561 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.
2008-05-13 GO:0033760 2'-deoxymugineic-acid 2'-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = mugineic acid + succinate + CO2.
2008-05-13 GO:0010397 apiogalacturonan metabolic process Added DEFINITION The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(l->3)-D-apiose) side chains via O-2 or O-3 links.
2008-05-13 GO:0047674 apiose 1-reductase activity Added DEFINITION Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + NADH.
2008-05-13 GO:0033350 apiose biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
2008-05-13 GO:0033349 apiose metabolic process Added DEFINITION The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
2008-05-13 GO:0050588 apo-beta-carotenoid-14',13'-dioxygenase activity Added DEFINITION Catalysis of the reaction: 8'-apo-beta-carotenol + O2 = 14'-apo-beta-carotenal + H2O.
2008-05-13 GO:0030221 basophil differentiation Added DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.
2008-05-13 GO:0002560 basophil mediated immunity Added DEFINITION Any process involved in the carrying out of an immune response by a basophil.
2008-05-13 GO:0032996 Bcl3-Bcl10 complex Added DEFINITION A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.
2008-05-13 GO:0033257 Bcl3/NF-kappaB2 complex Added DEFINITION A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.
2008-05-13 GO:0007610 behavior Added DEFINITION The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
2008-05-13 GO:0002209 behavioral defense response Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat to that organism.
2008-05-13 GO:0002211 behavioral defense response to insect Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.
2008-05-13 GO:0002212 behavioral defense response to nematode Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.
2008-05-13 GO:0001662 behavioral fear response Added DEFINITION An acute behavioral change resulting from a perceived external threat.
2008-05-13 GO:0051705 multi-organism behavior Added DEFINITION The processes by which an organism has an observable behavioral effect on another organism of the same or different species.
2008-05-13 GO:0048148 behavioral response to cocaine Added DEFINITION A change in the behavior of an organism as a result of a cocaine stimulus.
2008-05-13 GO:0048149 behavioral response to ethanol Added DEFINITION A change in the behavior of an organism as a result of an ethanol stimulus.
2008-05-13 GO:0048150 behavioral response to ether Added DEFINITION A change in the behavior of an organism as a result of an ether stimulus.
2008-05-13 GO:0035095 behavioral response to nicotine Added DEFINITION A change in the behavior of an organism as a result of a nicotine stimulus.
2008-05-13 GO:0051780 behavioral response to nutrient Added DEFINITION A change in the behavior of an organism as a result of a nutrient stimulus.
2008-05-13 GO:0048266 behavioral response to pain Added DEFINITION A change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
2008-05-13 GO:0042595 behavioral response to starvation Added DEFINITION A change in the behavior of an organism as a result of deprivation of nourishment.
2008-05-13 GO:0042630 behavioral response to water deprivation Added DEFINITION A change in the behavior of an organism as a result of deprivation of water.
2008-05-13 GO:0002210 behavioral response to wounding Added DEFINITION A behavioral response resulting from wounding.
2008-05-13 GO:0015900 benomyl transport Added DEFINITION The directed movement of benomyl into, out of, within or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.
2008-05-13 GO:0015242 benomyl transporter activity Added DEFINITION Enables the directed movement of benomyl into, out of, within or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.
2008-05-13 GO:0015310 benomyl:proton antiporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).
2008-05-13 GO:0003681 bent DNA binding Added DEFINITION Interacting selectively with DNA in a bent conformation.
2008-05-13 GO:0006326 bent DNA binding Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.
2008-05-13 GO:0018477 benzaldehyde dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.
2008-05-13 GO:0019115 benzaldehyde dehydrogenase activity Added DEFINITION Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.
2008-05-13 GO:0018619 benzene 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: benzene + NADH + H+ + O2 = cis-cyclohexa-3,5-diene-1,2-diol + NAD+.
2008-05-13 GO:0042537 benzene-containing compound metabolic process Added DEFINITION The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
2008-05-13 GO:0018910 benzene metabolic process Added DEFINITION The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.
2008-05-13 GO:0018606 benzenesulfonate dioxygenase activity Added DEFINITION Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.
2008-05-13 GO:0018623 benzoate 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.
2008-05-13 GO:0018664 benzoate 4-monooxygenase activity Added DEFINITION Catalysis of the reaction: benzoate + NADPH + H+ + O2 = 4-hydroxybenzoate + NADP+ + H2O.
2008-05-13 GO:0043639 benzoate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
2008-05-13 GO:0010128 benzoate catabolic process via CoA ligation Added DEFINITION The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway.
2008-05-13 GO:0043640 benzoate catabolic process via hydroxylation Added DEFINITION The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol.
2008-05-13 GO:0018874 benzoate metabolic process Added DEFINITION The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
2008-05-13 GO:0042919 benzoate transport Added DEFINITION The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of, within or between cells.
2008-05-13 GO:0042925 benzoate transporter activity Added DEFINITION Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of, within or between cells.
2008-05-13 GO:0018858 benzoate-CoA ligase activity Added DEFINITION Catalysis of the reaction: ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA. Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the corresponding chlorobenzoates.
2008-05-13 GO:0008503 benzodiazepine receptor activity Added DEFINITION Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.
2008-05-13 GO:0030156 benzodiazepine receptor binding Added DEFINITION Interacting selectively with the peripheral benzodiazepine receptor (PBR).
2008-05-13 GO:0048228 actin cortical patch distribution Added DEFINITION The processes that establish the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells.
2008-05-13 GO:0051666 actin cortical patch localization Added DEFINITION The processes by which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
2008-05-13 GO:0003780 actin cross-linking activity Added DEFINITION OBSOLETE. Interacting selectively with two actin filaments to anchor them together.
2008-05-13 GO:0051764 actin crosslink formation Added DEFINITION The process by which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.
2008-05-13 GO:0015629 actin cytoskeleton Added DEFINITION The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
2008-05-13 GO:0030036 actin cytoskeleton organization Added DEFINITION A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2008-05-13 GO:0031532 actin cytoskeleton reorganization Added DEFINITION Dynamic structural changes to the assembly and arrangement of the actin cytoskeleton, comprising actin filaments and their associated proteins.
2008-05-13 GO:0003787 actin depolymerizing activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0005884 actin filament Added DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2008-05-13 GO:0051015 actin filament binding Added DEFINITION Interacting selectively with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2008-05-13 GO:0032432 actin filament bundle Added DEFINITION An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
2008-05-13 GO:0051017 actin filament bundle assembly Added DEFINITION The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
2008-05-13 GO:0051693 actin filament capping Added DEFINITION The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
2008-05-13 GO:0030042 actin filament depolymerization Added DEFINITION Disassembly of actin filaments by the removal of actin monomers from a filament.
2008-05-13 GO:0030043 actin filament fragmentation Added DEFINITION The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.
2008-05-13 GO:0051639 actin filament network formation Added DEFINITION The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.
2008-05-13 GO:0007015 actin filament organization Added DEFINITION Control of the spatial distribution of actin filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
2008-05-13 GO:0030041 actin filament polymerization Added DEFINITION Assembly of actin filaments by the addition of actin monomers to a filament.
2008-05-13 GO:0030037 actin filament reorganization involved in cell cycle Added DEFINITION The cell cycle process whereby rearrangement of the spatial distribution of actin filaments and associated proteins occurs.
2008-05-13 GO:0051014 actin filament severing Added DEFINITION The process by which an actin filament is broken down into smaller filaments.
2008-05-13 GO:0003789 actin filament severing activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0051695 actin filament uncapping Added DEFINITION The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
2008-05-13 GO:0030048 actin filament-based movement Added DEFINITION Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
2008-05-13 GO:0030029 actin filament-based process Added DEFINITION Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.
2008-05-13 GO:0033392 actin homodimerization activity Added DEFINITION Interacting selectively with an identical actin monomer to form a homodimer.
2008-05-13 GO:0003786 actin lateral binding Added DEFINITION Interacting selectively with an actin filament along its length.
2008-05-13 GO:0030047 actin modification Added DEFINITION Covalent modification of an actin molecule.
2008-05-13 GO:0003790 actin modulating activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0003785 actin monomer binding Added DEFINITION Interacting selectively with monomeric actin, also known as G-actin.
2008-05-13 GO:0003788 actin monomer sequestering activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0045010 actin nucleation Added DEFINITION The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
2008-05-13 GO:0031289 actin phosphorylation Added DEFINITION The transfer of one or more phosphate groups to an actin molecule.
2008-05-13 GO:0008154 actin polymerization or depolymerization Added DEFINITION Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.
2008-05-13 GO:0008651 actin polymerizing activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0031002 actin rod Added DEFINITION A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Found in the germinating spores of Dictyostelium discoideum.
2008-05-13 GO:0031247 actin rod assembly Added DEFINITION The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules.
2008-05-13 GO:0031003 actin tubule Added DEFINITION A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.
2008-05-13 GO:0030898 actin-dependent ATPase activity Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, requiring the presence of an actin filament to accelerate release of ADP and phosphate.
2008-05-13 GO:0003856 3-dehydroquinate synthase activity Added DEFINITION Catalysis of the reaction: 3-deoxy-arabino-heptulosonate 7-phosphate = 3-dehydroquinate + phosphate.
2008-05-13 GO:0046565 3-dehydroshikimate dehydratase activity Added DEFINITION Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate (protocatechuate) + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.
2008-05-13 GO:0047560 3-dehydrosphinganine reductase activity Added DEFINITION Catalysis of the reaction: sphinganine + NADP+ = 3-dehydrosphinganine + NADPH + H+.
2008-05-13 GO:0008689 3-demethylubiquinone-9 3-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.
2008-05-13 GO:0033937 3-deoxy-2-octulosonidase activity Added DEFINITION Catalysis of the reaction: endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.
2008-05-13 GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity Added DEFINITION Catalysis of the reaction: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate.
2008-05-13 GO:0008676 3-deoxy-8-phosphooctulonate synthase activity Added DEFINITION Catalysis of the reaction: phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.
2008-05-13 GO:0047439 3-deoxy-D-manno-octulosonate aldolase activity Added DEFINITION Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.
2008-05-13 GO:0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity Added DEFINITION Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.
2008-05-13 GO:0019143 3-deoxy-manno-octulosonate-8-phosphatase activity Added DEFINITION Catalysis of the reaction: 3-deoxy-D-manno-octulosonate 8-phosphate + H2O = 3-deoxy-D-manno-octulosonate + phosphate.
2008-05-13 GO:0050534 3-deoxyoctulosonase activity Added DEFINITION Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.
2008-05-13 GO:0050441 3-ethylmalate synthase activity Added DEFINITION Catalysis of the reaction: butanoyl-CoA + H2O + glyoxylate = 3-ethylmalate + CoA .
2008-05-13 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity Added DEFINITION Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.
2008-05-13 GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
2008-05-13 GO:0047431 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methylpyridine-4,5-dicarboxylate = CO2 + 3-hydroxy-2-methylpyridine-5-carboxylate.
2008-05-13 GO:0047081 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + NAD(P)H + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NAD(P)+ + 2-(acetamidomethylene)succinate.
2008-05-13 GO:0050586 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methyl-1H-quinolin-4-one + O2 = N-acetylanthranilate + CO.
2008-05-13 GO:0047445 3-hydroxy-3-isohexenylglutaryl-CoA lyase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = acetate + 7-methyl-3-oxooctanoyl-CoA.
2008-05-13 GO:0047078 3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.
2008-05-13 GO:0018812 3-hydroxyacyl-CoA dehydratase activity Added DEFINITION Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).
2008-05-13 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+.
2008-05-13 GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: CH3-CHOH-CH2-[CH2]n-CO-[acyl-carrier protein] = H2O + CH3-CH-CH-[CH2]n-CO-[acyl-carrier protein].
2008-05-13 GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2008-05-13 GO:0030767 3-hydroxyanthranilate 4-C-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate.
2008-05-13 GO:0047561 3-hydroxyanthranilate oxidase activity Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2.
2008-05-13 GO:0047562 3-hydroxyaspartate aldolase activity Added DEFINITION Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = glycine + glyoxylate.
2008-05-13 GO:0047563 3-hydroxybenzoate 2-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxybenzoate + donor-H2 + O2 = 2,3-dihydroxybenzoate + acceptor + H2O.
2008-05-13 GO:0018668 3-hydroxybenzoate 4-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxybenzoate + NADPH + H+ + O2 = 3,4-dihydroxybenzoate + NADP+ + H2O.
2008-05-13 GO:0018669 3-hydroxybenzoate 6-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxybenzoate + NADH + H+ + O2 = 2,5-dihydroxybenzoate + NAD+ + H2O.
2008-05-13 GO:0018921 3-hydroxybenzyl alcohol metabolic process Added DEFINITION The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum.
2008-05-13 GO:0047048 3-hydroxybenzyl-alcohol dehydrogenase activity Added DEFINITION Catalysis of the reaction: NADP+ + 3-hydroxybenzyl alcohol = NADPH + H+ + 3-hydroxybenzaldehyde.
2008-05-13 GO:0003858 3-hydroxybutyrate dehydrogenase activity Added DEFINITION Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH + H+.
2008-05-13 GO:0003859 3-hydroxybutyryl-CoA dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O.
2008-05-13 GO:0008691 3-hydroxybutyryl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.
2008-05-13 GO:0008692 3-hydroxybutyryl-CoA epimerase activity Added DEFINITION Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.
2008-05-13 GO:0018712 3-hydroxybutyryl-CoA thiolase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.
2008-05-13 GO:0047564 3-hydroxycyclohexanone dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxycyclohexanone + acceptor = cyclohexane-1,3-dione + reduced acceptor.
2008-05-13 GO:0008693 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O.
2008-05-13 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
2008-05-13 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.
2008-05-13 GO:0047155 3-hydroxymethylcephem carbamoyltransferase activity Added DEFINITION Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem.
2008-05-13 GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein].
2008-05-13 GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O.
2008-05-13 GO:0015551 3-hydroxyphenyl propanoate transmembrane transporter activity Added DEFINITION Catalysis of the transfer of 3-hydroxyphenyl propanoate from one side of the membrane to the other.
2008-05-13 GO:0015731 3-hydroxyphenyl propanoate transport Added DEFINITION The directed movement of 3-hydroxyphenyl propanoate into, out of, within or between cells.
2008-05-13 GO:0015540 3-hydroxyphenyl propionate:hydrogen ion symporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).
2008-05-13 GO:0047094 3-hydroxyphenylacetate 6-hydroxylase activity Added DEFINITION Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.
2008-05-13 GO:0033275 actin-myosin filament sliding Added DEFINITION The sliding movement of actin thin filaments and myosin thick filaments past each other.
2008-05-13 GO:0008129 actinidain activity Added DEFINITION Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'.
2008-05-13 GO:0042805 actinin binding Added DEFINITION Interacting selectively with actinin, any member of a family of proteins that crosslink F-actin.
2008-05-13 GO:0034304 actinomycete-type spore formation Added DEFINITION The process by which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.
2008-05-13 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) Added DEFINITION A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.
2008-05-13 GO:0031278 alpha-1,2-galactosyltransferase activity Added DEFINITION Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.
2008-05-13 GO:0000026 alpha-1,2-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.
2008-05-13 GO:0001962 alpha-1,3-galactosyltransferase activity Added DEFINITION Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,3-linkage.
2008-05-13 GO:0047657 alpha-1,3-glucan synthase activity Added DEFINITION Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.
2008-05-13 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2 = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2.
2008-05-13 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.
2008-05-13 GO:0000033 alpha-1,3-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,3-linkage.
2008-05-13 GO:0033201 alpha-1,4-glucan synthase activity Added DEFINITION Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.
2008-05-13 GO:0047211 alpha-1,4-glucan-protein synthase (ADP-forming) activity Added DEFINITION Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP.
2008-05-13 GO:0047210 alpha-1,4-glucan-protein synthase (UDP-forming) activity Added DEFINITION Catalysis of the reaction: protein + UDP-D-glucose = alpha-D-glucosyl-protein + UDP.
2008-05-13 GO:0051751 alpha-1,4-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,4-linkage.
2008-05-13 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity Added DEFINITION Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.
2008-05-13 GO:0047253 alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.
2008-05-13 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors.
2008-05-13 GO:0008455 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.
2008-05-13 GO:0000009 alpha-1,6-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,6-linkage.
2008-05-13 GO:0000136 alpha-1,6-mannosyltransferase complex Added DEFINITION A large, multiprotein complex with alpha-1,6 mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.
2008-05-13 GO:0019923 alpha-1-microglobulin-chromophore linkage Added DEFINITION The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds.
2008-05-13 GO:0031691 alpha-1A adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-1A adrenergic receptor.
2008-05-13 GO:0031692 alpha-1B adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-1B adrenergic receptor.
2008-05-13 GO:0031693 alpha-1D adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-1D adrenergic receptor.
2008-05-13 GO:0016975 alpha-2 macroglobulin Added DEFINITION OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates.
2008-05-13 GO:0016964 alpha-2 macroglobulin receptor activity Added DEFINITION Combining with an alpha-2 macroglobulin to initiate a change in cell activity.
2008-05-13 GO:0016963 alpha-2 macroglobulin receptor-associated protein activity Added DEFINITION OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains.
2008-05-13 GO:0031694 alpha-2A adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-2A adrenergic receptor.
2008-05-13 GO:0031695 alpha-2B adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-2B adrenergic receptor.
2008-05-13 GO:0031696 alpha-2C adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-2C adrenergic receptor.
2008-05-13 GO:0051393 alpha-actinin binding Added DEFINITION Interacting selectively with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
2008-05-13 GO:0033953 alpha-agarase activity Added DEFINITION Catalysis of the reaction: endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.
2008-05-13 GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Added DEFINITION An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
2008-05-13 GO:0043289 apocarotenoid biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.
2008-05-13 GO:0043290 apocarotenoid catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
2008-05-13 GO:0043288 apocarotenoid metabolic process Added DEFINITION The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
2008-05-13 GO:0005320 apolipoprotein Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0034186 apolipoprotein A-I binding Added DEFINITION Interacting selectively with apolipoprotein A-I.
2008-05-13 GO:0034188 apolipoprotein A-I receptor activity Added DEFINITION Combining with apolipoprotein A-I to initiate a change in cell activity.
2008-05-13 GO:0034191 apolipoprotein A-I receptor binding Added DEFINITION Interacting selectively with an apolipoprotein A-I receptor.
2008-05-13 GO:0030895 apolipoprotein B mRNA editing enzyme complex Added DEFINITION Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).
2008-05-13 GO:0034185 apolipoprotein binding Added DEFINITION Interacting selectively with an apolipoprotein, the protein component of a lipoprotein complex.
2008-05-13 GO:0034187 apolipoprotein E binding Added DEFINITION Interacting selectively with apolipoprotein E.
2008-05-13 GO:0030227 apolipoprotein E receptor activity Added DEFINITION Combining with apolipoprotein E to initiate a change in cell activity.
2008-05-13 GO:0050749 apolipoprotein E receptor binding Added DEFINITION Interacting selectively with an apolipoprotein E receptor.
2008-05-13 GO:0030226 apolipoprotein receptor activity Added DEFINITION Combining with an apolipoprotein, the protein component of a lipoprotein, to initiate a change in cell activity.
2008-05-13 GO:0034190 apolipoprotein receptor binding Added DEFINITION Interacting selectively with an apolipoprotein receptor.
2008-05-13 GO:0018989 apolysis Added DEFINITION The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.
2008-05-13 GO:0048046 apoplast Added DEFINITION The protoplasts of cells in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2008-05-13 GO:0015283 apoptogenic cytochrome c release channel activity Added DEFINITION OBSOLETE.
2008-05-13 GO:0006915 apoptotic process Added DEFINITION A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface.
2008-05-13 GO:0016506 apoptosis activator activity Added DEFINITION OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.
2008-05-13 GO:0008189 apoptosis inhibitor activity Added DEFINITION OBSOLETE. The function held by products which directly block any step in the process of apoptosis.
2008-05-13 GO:0060057 apoptotic process involved in mammary gland involution Added DEFINITION The form of programmed cell death that triggers the activity of proteolytic caspases, whose actions dismantle the mammary epithelial cells resulting in their death.
2008-05-13 GO:0016329 apoptosis regulator activity Added DEFINITION OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.
2008-05-13 GO:0043293 apoptosome Added DEFINITION A multisubunit protein complex involved in the activation of apoptosis. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
2008-05-13 GO:0043277 apoptotic cell clearance Added DEFINITION The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
2008-05-13 GO:0030263 apoptotic chromosome condensation Added DEFINITION The compaction of chromatin during apoptosis.
2008-05-13 GO:0008637 apoptotic mitochondrial changes Added DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2008-05-13 GO:0030262 apoptotic nuclear changes Added DEFINITION The morphological and physiological alterations undergone by the nucleus during apoptosis.
2008-05-13 GO:0008632 apoptotic program Added DEFINITION The intracellular signaling cascade that results when a cell is triggered to undergo apoptosis.
2008-05-13 GO:0048736 appendage development Added DEFINITION The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism. For example a limb or a branch.
2008-05-13 GO:0035107 appendage morphogenesis Added DEFINITION The process by which the anatomical structures of appendages are generated and organized. Morphogenesis pertains to the creation of form. An appendage is an organ or part that is attached to the trunk of an organism. For example a limb or a branch.
2008-05-13 GO:0035285 appendage segmentation Added DEFINITION Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.
2008-05-13 GO:0007475 apposition of dorsal and ventral imaginal disc-derived wing surfaces Added DEFINITION The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
2008-05-13 GO:0004050 apyrase activity Added DEFINITION OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate.
2008-05-13 GO:0050444 aquacobalamin reductase (NADPH) activity Added DEFINITION Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+.
2008-05-13 GO:0047138 aquacobalamin reductase activity Added DEFINITION Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+.
2008-05-13 GO:0034075 arabidiol synthase activity Added DEFINITION Catalysis of the reaction: oxidosqualene = arabidiol ((3S,13R,14R)-malabarica-17E,21-dien-3beta,14-diol).
2008-05-13 GO:0031222 arabinan catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of arabinan, a branched homopolymer of L-arabinose.
2008-05-13 GO:0046558 arabinan endo-1,5-alpha-L-arabinosidase activity Added DEFINITION Catalysis of the endohydrolysis of 1,5-alpha-arabinofuranosidic linkages in 1,5-arabinans.
2008-05-13 GO:0031221 arabinan metabolic process Added DEFINITION The chemical reactions and pathways involving arabinan, a branched homopolymer of L-arabinose.
2008-05-13 GO:0046233 3-hydroxyphenylacetate biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
2008-05-13 GO:0009265 2'-deoxyribonucleotide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.
2008-05-13 GO:0009394 2'-deoxyribonucleotide metabolic process Added DEFINITION The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.
2008-05-13 GO:0018740 2'-hydroxybiphenyl-2-sulfinate desulfinase activity Added DEFINITION Catalysis of the reaction: 2-(2-hydroxyphenyl)benzenesulfinate + H2O = 2-hydroxybiphenyl + SO3(2-) (sulfite).
2008-05-13 GO:0047525 2'-hydroxydaidzein reductase activity Added DEFINITION Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzen + NADPH + H+.
2008-05-13 GO:0047526 2'-hydroxyisoflavone reductase activity Added DEFINITION Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.
2008-05-13 GO:0008665 2'-phosphotransferase activity Added DEFINITION Catalysis of the transfer of a phosphate group from one compound to the 2' position of another.
2008-05-13 GO:0018556 2,2',3-trihydroxybiphenyl dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).
2008-05-13 GO:0047432 2,2-dialkylglycine decarboxylase (pyruvate) activity Added DEFINITION Catalysis of the reaction: 2,2-dialkylglycine + pyruvate = dialkyl ketone + L-alanine + CO2.
2008-05-13 GO:0008666 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Added DEFINITION Catalysis of the reaction: succinyl-CoA + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.
2008-05-13 GO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Added DEFINITION Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; requires the cofactor 2,3-bisphosphoglycerate.
2008-05-13 GO:0046537 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Added DEFINITION Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate without requiring the cofactor 2,3-bisphosphoglycerate.
2008-05-13 GO:0047189 2,3-diaminopropionate N-oxalyltransferase activity Added DEFINITION Catalysis of the reaction: L-2,3-diaminopropanoate + oxalyl-CoA = N3-oxalyl-L-23-diaminopropanoate + CoA.
2008-05-13 GO:0008667 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydro-2,3-dihydroxybenzoate + NAD+ = 2,3-dihydroxybenzoate + NADH + H+.
2008-05-13 GO:0018542 2,3-dihydroxy DDT 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.
2008-05-13 GO:0018511 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity Added DEFINITION Catalysis of the reaction: cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD+ = 2,3-dihydroxy-p-cumate + NADH + H+.
2008-05-13 GO:0018498 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity Added DEFINITION Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.
2008-05-13 GO:0018563 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.
2008-05-13 GO:0018571 2,3-dihydroxy-p-cumate dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.
2008-05-13 GO:0047072 2,3-dihydroxybenzoate 2,3-dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + 2,3-dihydroxybenzoate = 2-carboxy-cis,cis-muconate.
2008-05-13 GO:0045133 2,3-dihydroxybenzoate 3,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 3-carboxy-2-hydroxymuconate semialdehyde.
2008-05-13 GO:0018790 2,3-dihydroxybenzoate decarboxylase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybenzoate + H+ = CO2 + catechol.
2008-05-13 GO:0047527 2,3-dihydroxybenzoate-serine ligase activity Added DEFINITION Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.
2008-05-13 GO:0043898 2,3-dihydroxybiphenyl 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.
2008-05-13 GO:0047528 2,3-dihydroxyindole 2,3-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxyindole + O2 = anthranilate + CO2.
2008-05-13 GO:0043715 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity Added DEFINITION Catalysis of the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
2008-05-13 GO:0047529 2,3-dimethylmalate lyase activity Added DEFINITION Catalysis of the reaction: 2,3-dimethylmalate = propanoate + pyruvate.
2008-05-13 GO:0047073 2,4'-dihydroxyacetophenone dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + 2',4'-dihydroxyacetophenone = formate + p-hydroxybenzoate.
2008-05-13 GO:0046227 2,4,5-trichlorophenoxyacetic acid biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.
2008-05-13 GO:0046228 2,4,5-trichlorophenoxyacetic acid catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.
2008-05-13 GO:0018980 2,4,5-trichlorophenoxyacetic acid metabolic process Added DEFINITION The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.
2008-05-13 GO:0018584 2,4,5-trichlorophenoxyacetic acid oxygenase activity Added DEFINITION Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.
2008-05-13 GO:0046255 2,4,6-trinitrotoluene biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene.
2008-05-13 GO:0046256 2,4,6-trinitrotoluene catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.
2008-05-13 GO:0018974 2,4,6-trinitrotoluene metabolic process Added DEFINITION The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.
2008-05-13 GO:0047530 2,4-diaminopentanoate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+.
2008-05-13 GO:0046297 2,4-dichlorobenzoate biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
2008-05-13 GO:0046298 2,4-dichlorobenzoate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
2008-05-13 GO:0018898 2,4-dichlorobenzoate metabolic process Added DEFINITION The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
2008-05-13 GO:0018857 2,4-dichlorobenzoate-CoA ligase activity Added DEFINITION Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.
2008-05-13 GO:0018516 2,4-dichlorobenzoyl-CoA reductase activity Added DEFINITION Catalysis of the reaction: 4-chlorobenzoyl-CoA + NADP+ + HCl = 2,4-dichlorobenzoyl-CoA + NADPH + H+.
2008-05-13 GO:0018666 2,4-dichlorophenol 6-monooxygenase activity Added DEFINITION Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.
2008-05-13 GO:0015792 arabinitol transport Added DEFINITION The directed movement of arabitol into, out of, within or between cells. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
2008-05-13 GO:0031218 arabinogalactan endo-1,4-beta-galactosidase activity Added DEFINITION Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in arabinogalactans.
2008-05-13 GO:0001761 beta-alanine transmembrane transporter activity Added DEFINITION Catalysis of the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.
2008-05-13 GO:0001762 beta-alanine transport Added DEFINITION The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of, within or between cells.
2008-05-13 GO:0016223 beta-alanine-pyruvate transaminase activity Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.
2008-05-13 GO:0047697 beta-alanopine dehydrogenase activity Added DEFINITION Catalysis of the reaction: beta-alanopine + NAD+ + H2O = beta-alanine + pyruvate + NADH.
2008-05-13 GO:0047698 beta-alanyl-CoA ammonia-lyase activity Added DEFINITION Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3.
2008-05-13 GO:0003832 beta-alanyl-dopamine hydrolase activity Added DEFINITION Catalysis of the conversion of beta-alanyl dopamine to dopamine (3,4-dihydroxyphenylethylamine).
2008-05-13 GO:0003833 beta-alanyl-dopamine synthase activity Added DEFINITION Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine).
2008-05-13 GO:0031964 beta-alanyl-histamine hydrolase activity Added DEFINITION Catalysis of the conversion of beta-alanyl-histamine to histamine.
2008-05-13 GO:0016161 beta-amylase activity Added DEFINITION Catalysis of the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.
2008-05-13 GO:0001540 beta-amyloid binding Added DEFINITION Interacting selectively with beta-amyloid peptide/protein and/or its precursor.
2008-05-13 GO:0034205 beta-amyloid formation Added DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
2008-05-13 GO:0050435 beta-amyloid metabolic process Added DEFINITION The chemical reactions and pathways involving beta-amyloid, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).
2008-05-13 GO:0042300 beta-amyrin synthase activity Added DEFINITION Catalysis of the cyclization and rearrangement of 2,3-oxidosqualene into beta-amyrin.
2008-05-13 GO:0033956 beta-apiosyl-beta-glucosidase activity Added DEFINITION Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.
2008-05-13 GO:0047406 beta-aspartyl-N-acetylglucosaminidase activity Added DEFINITION Catalysis of the reaction: H2O + 1-beta-aspartyl-N-acetyl-D-glucosaminylamine = L-asparagine + N-acetyl-D-glucosamine.
2008-05-13 GO:0008798 beta-aspartyl-peptidase activity Added DEFINITION Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.
2008-05-13 GO:0003834 beta-carotene 15,15'-monooxygenase activity Added DEFINITION Catalysis of the reaction: beta-carotene + O2 = 2 retinal.
2008-05-13 GO:0042411 beta-carotene hydroxylase activity Added DEFINITION Catalysis of the hydroxylation of both beta rings of beta-carotene to form zeaxanthine.
2008-05-13 GO:0008013 beta-catenin binding Added DEFINITION Interacting selectively with the beta subunit of the catenin complex.
2008-05-13 GO:0030877 beta-catenin destruction complex Added DEFINITION A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
2008-05-13 GO:0050448 beta-cyclopiazonate dehydrogenase activity Added DEFINITION Catalysis of the reaction: beta-cyclopiazonate + acceptor = alpha-cyclopiazonate + reduced acceptor.
2008-05-13 GO:0033907 beta-D-fucosidase activity Added DEFINITION Catalysis of the reaction: hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.
2008-05-13 GO:0047699 beta-diketone hydrolase activity Added DEFINITION Catalysis of the reaction: nonane-4,6-dione + H2O = pentan-2-one + butanoate.
2008-05-13 GO:0031626 beta-endorphin binding Added DEFINITION Interacting selectively with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.
2008-05-13 GO:0004979 beta-endorphin receptor activity Added DEFINITION Combining with beta-endorphin to initiate a change in cell activity.
2008-05-13 GO:0004564 beta-fructofuranosidase activity Added DEFINITION Catalysis of the hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.
2008-05-13 GO:0033944 beta-galactofuranosidase activity Added DEFINITION Catalysis of the reaction: hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.
2008-05-13 GO:0004565 beta-galactosidase activity Added DEFINITION Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.
2008-05-13 GO:0009341 beta-galactosidase complex Added DEFINITION A multimeric enzyme complex that in E. coli is an heterooctamer made up of four alpha subunits and four beta subunits. Catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.
2008-05-13 GO:0017030 beta-galactosidase stabilization activity Added DEFINITION OBSOLETE. Stabilization of the structure of beta-galactosidase.
2008-05-13 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Added DEFINITION Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R.
2008-05-13 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity Added DEFINITION Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine.
2008-05-13 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide.
2008-05-13 GO:0051274 beta-glucan biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of beta-glucans.
2008-05-13 GO:0051275 beta-glucan catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of beta-glucans.
2008-05-13 GO:0051273 beta-glucan metabolic process Added DEFINITION The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.
2008-05-13 GO:0015160 beta-glucan transmembrane transporter activity Added DEFINITION Catalysis of the transfer of beta-glucans from one side of the membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
2008-05-13 GO:0015775 beta-glucan transport Added DEFINITION The directed movement of beta-glucans into, out of, within or between cells. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
2008-05-13 GO:0015441 beta-glucan-transporting ATPase activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).
2008-05-13 GO:0047201 beta-glucogallin O-galloyltransferase activity Added DEFINITION Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1-O,6-O-digalloyl-beta-D-glucose + beta-D-glucose.
2008-05-13 GO:0047176 beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity Added DEFINITION Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + beta-D-glucose.
2008-05-13 GO:0008422 beta-glucosidase activity Added DEFINITION Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
2008-05-13 GO:0047700 beta-glucoside kinase activity Added DEFINITION Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.
2008-05-13 GO:0015573 beta-glucoside transmembrane transporter activity Added DEFINITION Catalysis of the transfer of beta-glucosides from one side of the membrane to the other. Beta-glucosides are glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
2008-05-13 GO:0047615 actinomycin lactonase activity Added DEFINITION Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.
2008-05-13 GO:0019227 neuronal action potential propagation Added DEFINITION A neurological process that causes the sequential depolarization of a neuron's cell membrane along an axon.
2008-05-13 GO:0006924 activation-induced cell death of T cells Added DEFINITION The process of apoptosis in activated T cells.
2008-05-13 GO:0050798 activated T cell proliferation Added DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2008-05-13 GO:0032397 activating MHC class I receptor activity Added DEFINITION Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
2008-05-13 GO:0007190 activation of adenylate cyclase activity Added DEFINITION Any process that initiates the activity of the inactive enzyme adenylate cyclase.
2008-05-13 GO:0051488 activation of anaphase-promoting complex activity Added DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex.
2008-05-13 GO:0051487 activation of anaphase-promoting complex activity involved in meiotic cell cycle Added DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the meiotic cell cycle.
2008-05-13 GO:0007092 activation of mitotic anaphase-promoting complex activity Added DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the mitotic cell cycle.
2008-05-13 GO:0032857 activation of ARF GTPase activity Added DEFINITION Any process that initiates the activity of the inactive enzyme ARF GTPase through the replacement of GDP by GTP.
2008-05-13 GO:0051519 activation of bipolar cell growth Added DEFINITION Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.
2008-05-13 GO:0002543 activation of blood coagulation via clotting cascade Added DEFINITION Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.
2008-05-13 GO:0032864 activation of Cdc42 GTPase activity Added DEFINITION Any process that initiates the activity of the inactive GTPase Cdc42 through the replacement of GDP by GTP.
2008-05-13 GO:0032793 positive regulation of CREB transcription factor activity Added DEFINITION Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.
2008-05-13 GO:0007239 activation of Hog1 Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0002253 activation of immune response Added DEFINITION Any process that initiates an immune response.
2008-05-13 GO:0002218 activation of innate immune response Added DEFINITION Any process that initiates an innate immune response.
2008-05-13 GO:0010531 activation of JAK1 kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-05-13 GO:0042977 activation of JAK2 kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
2008-05-13 GO:0042976 activation of Janus kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-05-13 GO:0007257 activation of JUN kinase activity Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
2008-05-13 GO:0007256 activation of JNKK activity Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2008-05-13 GO:0042655 activation of JNKKK activity Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase kinase activity in response to phosphorylation by a member of the MAP kinase kinase kinase kinase (MAPKKKK) family or another upstream kinase.
2008-05-13 GO:0030456 activation of MAPK (mating sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0007247 activation of MAPK (mating sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.
2008-05-13 GO:0000193 activation of MAPK (pseudohyphal growth) Added DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.
2008-05-13 GO:0000187 activation of MAPK activity Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
2008-05-13 GO:0000199 activation of MAPK activity involved in cell wall organization or biogenesis Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
2008-05-13 GO:0000169 activation of MAPK activity involved in osmosensory signaling pathway Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase activity during osmolarity sensing.
2008-05-13 GO:0030439 activation of MAPK during sporulation (sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0000205 activation of MAPK during sporulation (sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2008-05-13 GO:0030457 activation of MAPKK (mating sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0007246 activation of MAPKK (mating sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces.
2008-05-13 GO:0000192 activation of MAPKK (pseudohyphal growth) Added DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth.
2008-05-13 GO:0000186 activation of MAPKK activity Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2008-05-13 GO:0000198 activation of MAPKK activity involved in cell wall organization or biogenesis Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
2008-05-13 GO:0000168 activation of MAPKK activity involved in osmosensory signaling pathway Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase during osmolarity sensing.
2008-05-13 GO:0030440 activation of MAPKK during sporulation (sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0000204 activation of MAPKK during sporulation (sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2008-05-13 GO:0030458 activation of MAPKKK (mating sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0007245 activation of MAPKKK (mating sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.
2008-05-13 GO:0000191 activation of MAPKKK (pseudohyphal growth) Added DEFINITION OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth.
2008-05-13 GO:0000185 activation of MAPKKK activity Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2008-05-13 GO:0000197 activation of MAPKKK activity involved in cell wall organization or biogenesis Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
2008-05-13 GO:0000167 activation of MAPKKK activity involved in osmosensory signaling pathway Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during osmolarity sensing.
2008-05-13 GO:0019610 3-hydroxyphenylacetate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
2008-05-13 GO:0019609 3-hydroxyphenylacetate metabolic process Added DEFINITION The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
2008-05-13 GO:0042920 3-hydroxyphenylpropionic acid transport Added DEFINITION The directed movement of 3-hydroxyphenylpropionic acid into, out of, within or between cells.
2008-05-13 GO:0042926 3-hydroxyphenylpropionic acid transporter activity Added DEFINITION Enables the directed movement of 3-hydroxyphenylpropionic acid into, out of, within or between cells.
2008-05-13 GO:0018464 3-hydroxypimeloyl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxypimeloyl-CoA + NAD+ = 3-oxopimeloyl-CoA + NADH + H+.
2008-05-13 GO:0047565 3-hydroxypropionate dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: 3-hydroxypropanoate + NAD+ = 3-oxopropanoate + NADH + H+.
2008-05-13 GO:0018854 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity Added DEFINITION Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
2008-05-13 GO:0003861 3-isopropylmalate dehydratase activity Added DEFINITION Catalysis of the reaction: 3-isopropylmalate = 2-isopropylmaleate + H2O.
2008-05-13 GO:0009316 3-isopropylmalate dehydratase complex Added DEFINITION A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
2008-05-13 GO:0003862 3-isopropylmalate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.
2008-05-13 GO:0000253 3-keto sterol reductase activity Added DEFINITION Catalysis of the reaction: 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + NADPH + H+.
2008-05-13 GO:0043720 3-keto-5-aminohexanoate cleavage activity Added DEFINITION Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.
2008-05-13 GO:0006666 3-keto-sphinganine metabolic process Added DEFINITION The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
2008-05-13 GO:0050576 3-keto-steroid reductase activity Added DEFINITION Catalysis of the reaction: 4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NADP+ = 4-alpha-methyl-5-alpha-cholest-7-en-3-one + NADPH + H+.
2008-05-13 GO:0048258 3-ketoglucose-reductase activity Added DEFINITION Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.
2008-05-13 GO:0018713 3-ketopimelyl-CoA thiolase activity Added DEFINITION Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.
2008-05-13 GO:0047566 3-ketovalidoxylamine C-N-lyase activity Added DEFINITION Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one.
2008-05-13 GO:0016784 3-mercaptopyruvate sulfurtransferase activity Added DEFINITION Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
2008-05-13 GO:0018653 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.
2008-05-13 GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity Added DEFINITION Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.
2008-05-13 GO:0043807 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity Added DEFINITION Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2008-05-13 GO:0006621 protein retention in ER lumen Updated TERM protein retention in ER lumen
2008-05-13 GO:0008326 site-specific DNA-methyltransferase (cytosine-specific) activity Deleted TERM site-specific DNA-methyltransferase (cytosine-specific) activity
2008-05-13 GO:0034433 steroid esterification Added TERM steroid esterification
2008-05-13 GO:0034434 sterol esterification Added TERM sterol esterification
2008-05-13 GO:0034435 cholesterol esterification Added TERM cholesterol esterification
2008-05-13 GO:0034436 glycoprotein transport Added TERM glycoprotein transport
2008-05-13 GO:0034437 glycoprotein transporter activity Added TERM glycoprotein transporter activity
2008-05-13 GO:0034438 lipoprotein amino acid oxidation Added TERM lipoprotein amino acid oxidation
2008-05-13 GO:0034439 lipoprotein lipid oxidation Added TERM lipoprotein lipid oxidation
2008-05-13 GO:0034440 lipid oxidation Added TERM lipid oxidation
2008-05-13 GO:0034441 plasma lipoprotein particle oxidation Added TERM plasma lipoprotein oxidation
2008-05-13 GO:0034442 regulation of lipoprotein oxidation Added TERM regulation of lipoprotein oxidation
2008-05-13 GO:0034443 negative regulation of lipoprotein oxidation Added TERM negative regulation of lipoprotein oxidation
2008-05-13 GO:0034444 regulation of plasma lipoprotein particle oxidation Added TERM regulation of plasma lipoprotein oxidation
2008-05-13 GO:0034445 negative regulation of plasma lipoprotein particle oxidation Added TERM negative regulation of plasma lipoprotein oxidation
2008-05-13 GO:0043899 phosphoserine:homoserine phosphotransferase activity Added TERM phosphoserine:homoserine phosphotransferase activity
2008-05-13 GO:0045053 protein retention in Golgi apparatus Updated TERM protein retention in Golgi apparatus

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2008-05-13 GO:0030482 actin cable Added DEFINITION A long bundle of actin filaments, comprising filamentous actin and associated proteins, found in cells.
2008-05-13 GO:0045011 actin cable formation Added DEFINITION The assembly of the long bundles of actin filaments known as actin cables.
2008-05-13 GO:0030478 actin cap Added DEFINITION Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell.
2008-05-13 GO:0005870 actin capping protein of dynactin complex Added DEFINITION A heterodimer consisting of alpha and a beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex.
2008-05-13 GO:0030479 actin cortical patch Added DEFINITION Discrete actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2008-05-13 GO:0000147 actin cortical patch assembly Added DEFINITION Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
2008-05-13 GO:0005503 all-trans retinal binding Added DEFINITION Interacting selectively with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
2008-05-13 GO:0051786 all-trans-retinol 13,14-reductase activity Added DEFINITION Catalysis of the reaction: all-trans-13,14-dihydroretinol + acceptor = all-trans-retinol + reduced acceptor. Note that this reaction has only been observed to occur in the opposite direction.
2008-05-13 GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity Added DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2008-05-13 GO:0047652 allantoate deiminase activity Added DEFINITION Catalysis of the reaction: 2 H2O + 2 allantoate = O2 + 2 CO2 + 2 NH3 + 2 ureidoglycine.
2008-05-13 GO:0015124 allantoate transmembrane transporter activity Added DEFINITION Catalysis of the transfer of allantoate from one side of the membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.
2008-05-13 GO:0015719 allantoate transport Added DEFINITION The directed movement of allantoate into, out of, within or between cells.
2008-05-13 GO:0004037 allantoicase activity Added DEFINITION Catalysis of the reaction: allantoate + H2O = (-)-ureidoglycolate + urea.
2008-05-13 GO:0009442 allantoin assimilation pathway Added DEFINITION The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP.
2008-05-13 GO:0019428 allantoin biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
2008-05-13 GO:0000256 allantoin catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
2008-05-13 GO:0000255 allantoin metabolic process Added DEFINITION The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.
2008-05-13 GO:0047653 allantoin racemase activity Added DEFINITION Catalysis of the reaction: (S)(+)-allantoin = (R)(-)-allantoin.
2008-05-13 GO:0015720 allantoin transport Added DEFINITION The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of, within or between cells.
2008-05-13 GO:0005274 allantoin uptake transmembrane transporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.
2008-05-13 GO:0006838 allantoin/allantoate transport Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0004038 allantoinase activity Added DEFINITION Catalysis of the reaction: allantoin + H2O = allantoate.
2008-05-13 GO:0016086 allatostatin Added DEFINITION OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone.
2008-05-13 GO:0008261 allatostatin receptor activity Added DEFINITION Combining with allatostatin to initiate a change in cell activity.
2008-05-13 GO:0009978 allene oxide synthase activity Added DEFINITION Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.
2008-05-13 GO:0046423 allene-oxide cyclase activity Added DEFINITION Catalysis of the reaction: (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.
2008-05-13 GO:0047654 alliin lyase activity Added DEFINITION Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.
2008-05-13 GO:0004039 allophanate hydrolase activity Added DEFINITION Catalysis of the reaction: urea-1-carboxylate + H2O = 2 CO2 + 2 NH3.
2008-05-13 GO:0008786 allose 6-phosphate isomerase activity Added DEFINITION Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.
2008-05-13 GO:0046366 allose biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0046367 allose catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0008787 allose kinase activity Added DEFINITION Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.
2008-05-13 GO:0019313 allose metabolic process Added DEFINITION The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0015593 allose transmembrane transporter activity Added DEFINITION Catalysis of the transfer of allose from one side of the membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0015754 allose transport Added DEFINITION The directed movement of allose into, out of, within or between cells. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
2008-05-13 GO:0047655 allyl-alcohol dehydrogenase activity Added DEFINITION Catalysis of the reaction: allyl alcohol + NADP+ = acrolein + NADPH.
2008-05-13 GO:0051411 ALP binding Added DEFINITION Interacting selectively wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band.
2008-05-13 GO:0005658 alpha DNA polymerase:primase complex Added DEFINITION A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.
2008-05-13 GO:0031127 alpha-(1,2)-fucosyltransferase activity Added DEFINITION Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,2)-linkage.
2008-05-13 GO:0046920 alpha-(1->3)-fucosyltransferase activity Added DEFINITION Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,3)-linkage.
2008-05-13 GO:0046921 alpha-(1->6)-fucosyltransferase activity Added DEFINITION Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,6)-linkage.
2008-05-13 GO:0008788 alpha,alpha-phosphotrehalase activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate.
2008-05-13 GO:0004555 alpha,alpha-trehalase activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.
2008-05-13 GO:0033832 alpha,alpha-trehalose phosphorylase (configuration-retaining) activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.
2008-05-13 GO:0047656 alpha,alpha-trehalose phosphorylase activity Added DEFINITION Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
2008-05-13 GO:0047260 alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity Added DEFINITION Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.
2008-05-13 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Added DEFINITION Catalysis of the reaction: UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
2008-05-13 GO:0042868 antisense RNA metabolic process Added DEFINITION The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.
2008-05-13 GO:0009300 antisense RNA transcription Added DEFINITION The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
2008-05-13 GO:0045152 antisigma factor binding Added DEFINITION Interacting selectively with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.
2008-05-13 GO:0003800 antiviral response protein activity Added DEFINITION OBSOLETE. A protein involved in an antiviral response.
2008-05-13 GO:0001547 antral ovarian follicle growth Added DEFINITION Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.
2008-05-13 GO:0030121 AP-1 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network.
2008-05-13 GO:0030122 AP-2 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles.
2008-05-13 GO:0030123 AP-3 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo.
2008-05-13 GO:0030124 AP-4 adaptor complex Added DEFINITION An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.
2008-05-13 GO:0030119 AP-type membrane coat adaptor complex Added DEFINITION Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).
2008-05-13 GO:0060182 apelin receptor activity Added DEFINITION Combining with the peptide apelin to initiate a change in cell activity.
2008-05-13 GO:0031704 apelin receptor binding Added DEFINITION Interacting selectively with an apelin receptor.
2008-05-13 GO:0060183 apelin receptor signaling pathway Added DEFINITION The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands.
2008-05-13 GO:0001597 apelin-like receptor Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0019778 Atg12 activating enzyme activity Added DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
2008-05-13 GO:0019792 APG12 hydrolase activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0019777 Atg12 ligase activity Added DEFINITION Catalysis of the covalent attachment of the ubiquitin-like protein APG12 to other proteins.
2008-05-13 GO:0019779 Atg8 activating enzyme Added DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.
2008-05-13 GO:0019776 Atg8 ligase activity Added DEFINITION Catalysis of the covalent attachment of the ubiquitin-like protein APG8 to substrate molecules; phosphatidylethanolamine is a known substrate.
2008-05-13 GO:0019786 Atg8-specific protease activity Added DEFINITION Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
2008-05-13 GO:0046567 aphidicolan-16 beta-ol synthase activity Added DEFINITION Catalysis of the formation of aphidicolan-16 beta-ol from geranylgeranyl diphosphate.
2008-05-13 GO:0020007 apical complex Added DEFINITION Protruding complex at the anterior end of some life cycle stages of all apicomplexan parasites, involved in both the attachment and penetration of the host cell by the parasite.
2008-05-13 GO:0045179 apical cortex Added DEFINITION The region that lies just beneath the plasma membrane on the apical edge of a cell.
2008-05-13 GO:0005928 apical hemi-adherens junction Added DEFINITION An adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle.
2008-05-13 GO:0043297 apical junction assembly Added DEFINITION The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.
2008-05-13 GO:0043296 apical junction complex Added DEFINITION A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
2008-05-13 GO:0032579 apical lamina of hyaline layer Added DEFINITION A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.
2008-05-13 GO:0045177 apical part of cell Added DEFINITION The apical region of a cell.
2008-05-13 GO:0016324 apical plasma membrane Added DEFINITION Part of the plasma membrane at the apical end of the cell.
2008-05-13 GO:0045176 apical protein localization Added DEFINITION The processes by which a protein is transported to, or maintained in, apical regions of the cell.
2008-05-13 GO:0016327 apicolateral plasma membrane Added DEFINITION The apical end of the lateral plasma membrane of epithelial cells.
2008-05-13 GO:0020011 apicoplast Added DEFINITION The plastid organelle found in apicomplexans.
2008-05-13 GO:0030754 apigenin 4'-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.
2008-05-13 GO:0033737 1-pyrroline dehydrogenase activity Added DEFINITION Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.
2008-05-13 GO:0047425 1-pyrroline-4-hydroxy-2-carboxylate deaminase activity Added DEFINITION Catalysis of the reaction: H2O + 1-pyrroline-4-hydroxy-2-carboxylate = NH3 + 2,5-dioxopentanoate.
2008-05-13 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H+.
2008-05-13 GO:0050643 10-deacetylbaccatin III 10-O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III.
2008-05-13 GO:0009257 10-formyltetrahydrofolate biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
2008-05-13 GO:0009258 10-formyltetrahydrofolate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
2008-05-13 GO:0009256 10-formyltetrahydrofolate metabolic process Added DEFINITION The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
2008-05-13 GO:0030779 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine.
2008-05-13 GO:0050639 10-hydroxytaxane O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + 10-desacetyltaxuyunnanin C = CoA + taxuyunnanin C.
2008-05-13 GO:0033236 11-beta-hydroxysteroid dehydrogenase (NAD+) activity Added DEFINITION OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.
2008-05-13 GO:0033237 11-beta-hydroxysteroid dehydrogenase (NADP+) activity Added DEFINITION OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.
2008-05-13 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity Added DEFINITION Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+.
2008-05-13 GO:0005502 11-cis retinal binding Added DEFINITION Interacting selectively with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
2008-05-13 GO:0047520 11-cis-retinyl-palmitate hydrolase activity Added DEFINITION Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate.
2008-05-13 GO:0030766 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.
2008-05-13 GO:0047013 cholate 12-alpha dehydrogenase activity Added DEFINITION Catalysis of the reaction: NADP+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate = NADPH + H+ + 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate.
2008-05-13 GO:0047521 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-alpha,7-alpha,12-beta-trihydroxy-5-beta-cholanate + NADP+ = 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + NADPH + H+.
2008-05-13 GO:0030780 12-hydroxydihydrochelirubine 12-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-homocysteine + dihydromacarpine.
2008-05-13 GO:0016629 12-oxophytodienoate reductase activity Added DEFINITION Catalysis of the reaction: 8-((1R,2R)-3-oxo-2-((Z)-pent-2-enyl)cyclopentyl)octanoate + NADP+ = (15Z)-12-oxophyto-10,15-dienoate + NADPH.
2008-05-13 GO:0047229 13-hydroxydocosanoate 13-beta-glucosyltransferase activity Added DEFINITION Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.
2008-05-13 GO:0047203 13-hydroxylupinine O-tigloyltransferase activity Added DEFINITION Catalysis of the reaction: 13-hydroxylupinine + (E)-2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyl)oxylupinine + CoA.
2008-05-13 GO:0050617 15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity Added DEFINITION Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
2008-05-13 GO:0047034 15-hydroxyicosatetraenoate dehydrogenase activity Added DEFINITION Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.
2008-05-13 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.
2008-05-13 GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate = NADPH + H+ + (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate.
2008-05-13 GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.
2008-05-13 GO:0047033 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-dienoate.
2008-05-13 GO:0047522 15-oxoprostaglandin 13-oxidase activity Added DEFINITION Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.
2008-05-13 GO:0047455 16-alpha-hydroxyprogesterone dehydratase activity Added DEFINITION Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.
2008-05-13 GO:0047005 16-alpha-hydroxysteroid dehydrogenase activity Added DEFINITION Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.
2008-05-13 GO:0047524 16-hydroxysteroid epimerase activity Added DEFINITION Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.
2008-05-13 GO:0030768 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxy-tabersonine = S-adenosyl-L-homocysteine + deacetoxyvindoline.
2008-05-13 GO:0047442 17-alpha-hydroxyprogesterone aldolase activity Added DEFINITION Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione.
2008-05-13 GO:0047162 17-O-deacetylvindoline O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: 17-O-deacetylvindoline + acetyl-CoA = vindoline + CoA.
2008-05-13 GO:0047311 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity Added DEFINITION Catalysis of the reaction: pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol = L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol.
2008-05-13 GO:0051537 2 iron, 2 sulfur cluster binding Added DEFINITION Interacting selectively with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
2008-05-13 GO:0008663 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity Added DEFINITION Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
2008-05-13 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity Added DEFINITION Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.
2008-05-13 GO:0019361 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
2008-05-13 GO:0046432 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process Added DEFINITION The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
2008-05-13 GO:0001730 2'-5'-oligoadenylate synthetase activity Added DEFINITION Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. Requires binding of double-stranded RNA.
2008-05-13 GO:0018561 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.
2008-05-13 GO:0033760 2'-deoxymugineic-acid 2'-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = mugineic acid + succinate + CO2.
2008-05-13 GO:0010397 apiogalacturonan metabolic process Added DEFINITION The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(l->3)-D-apiose) side chains via O-2 or O-3 links.
2008-05-13 GO:0047674 apiose 1-reductase activity Added DEFINITION Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + NADH.
2008-05-13 GO:0033350 apiose biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
2008-05-13 GO:0033349 apiose metabolic process Added DEFINITION The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
2008-05-13 GO:0050588 apo-beta-carotenoid-14',13'-dioxygenase activity Added DEFINITION Catalysis of the reaction: 8'-apo-beta-carotenol + O2 = 14'-apo-beta-carotenal + H2O.
2008-05-13 GO:0030221 basophil differentiation Added DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.
2008-05-13 GO:0002560 basophil mediated immunity Added DEFINITION Any process involved in the carrying out of an immune response by a basophil.
2008-05-13 GO:0032996 Bcl3-Bcl10 complex Added DEFINITION A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.
2008-05-13 GO:0033257 Bcl3/NF-kappaB2 complex Added DEFINITION A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.
2008-05-13 GO:0007610 behavior Added DEFINITION The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
2008-05-13 GO:0002209 behavioral defense response Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat to that organism.
2008-05-13 GO:0002211 behavioral defense response to insect Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.
2008-05-13 GO:0002212 behavioral defense response to nematode Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.
2008-05-13 GO:0001662 behavioral fear response Added DEFINITION An acute behavioral change resulting from a perceived external threat.
2008-05-13 GO:0051705 multi-organism behavior Added DEFINITION The processes by which an organism has an observable behavioral effect on another organism of the same or different species.
2008-05-13 GO:0048148 behavioral response to cocaine Added DEFINITION A change in the behavior of an organism as a result of a cocaine stimulus.
2008-05-13 GO:0048149 behavioral response to ethanol Added DEFINITION A change in the behavior of an organism as a result of an ethanol stimulus.
2008-05-13 GO:0048150 behavioral response to ether Added DEFINITION A change in the behavior of an organism as a result of an ether stimulus.
2008-05-13 GO:0035095 behavioral response to nicotine Added DEFINITION A change in the behavior of an organism as a result of a nicotine stimulus.
2008-05-13 GO:0051780 behavioral response to nutrient Added DEFINITION A change in the behavior of an organism as a result of a nutrient stimulus.
2008-05-13 GO:0048266 behavioral response to pain Added DEFINITION A change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
2008-05-13 GO:0042595 behavioral response to starvation Added DEFINITION A change in the behavior of an organism as a result of deprivation of nourishment.
2008-05-13 GO:0042630 behavioral response to water deprivation Added DEFINITION A change in the behavior of an organism as a result of deprivation of water.
2008-05-13 GO:0002210 behavioral response to wounding Added DEFINITION A behavioral response resulting from wounding.
2008-05-13 GO:0015900 benomyl transport Added DEFINITION The directed movement of benomyl into, out of, within or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.
2008-05-13 GO:0015242 benomyl transporter activity Added DEFINITION Enables the directed movement of benomyl into, out of, within or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.
2008-05-13 GO:0015310 benomyl:proton antiporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).
2008-05-13 GO:0003681 bent DNA binding Added DEFINITION Interacting selectively with DNA in a bent conformation.
2008-05-13 GO:0006326 bent DNA binding Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.
2008-05-13 GO:0018477 benzaldehyde dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.
2008-05-13 GO:0019115 benzaldehyde dehydrogenase activity Added DEFINITION Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.
2008-05-13 GO:0018619 benzene 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: benzene + NADH + H+ + O2 = cis-cyclohexa-3,5-diene-1,2-diol + NAD+.
2008-05-13 GO:0042537 benzene-containing compound metabolic process Added DEFINITION The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
2008-05-13 GO:0018910 benzene metabolic process Added DEFINITION The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.
2008-05-13 GO:0018606 benzenesulfonate dioxygenase activity Added DEFINITION Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.
2008-05-13 GO:0018623 benzoate 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.
2008-05-13 GO:0018664 benzoate 4-monooxygenase activity Added DEFINITION Catalysis of the reaction: benzoate + NADPH + H+ + O2 = 4-hydroxybenzoate + NADP+ + H2O.
2008-05-13 GO:0043639 benzoate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
2008-05-13 GO:0010128 benzoate catabolic process via CoA ligation Added DEFINITION The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway.
2008-05-13 GO:0043640 benzoate catabolic process via hydroxylation Added DEFINITION The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol.
2008-05-13 GO:0018874 benzoate metabolic process Added DEFINITION The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
2008-05-13 GO:0042919 benzoate transport Added DEFINITION The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of, within or between cells.
2008-05-13 GO:0042925 benzoate transporter activity Added DEFINITION Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of, within or between cells.
2008-05-13 GO:0018858 benzoate-CoA ligase activity Added DEFINITION Catalysis of the reaction: ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA. Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the corresponding chlorobenzoates.
2008-05-13 GO:0008503 benzodiazepine receptor activity Added DEFINITION Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.
2008-05-13 GO:0030156 benzodiazepine receptor binding Added DEFINITION Interacting selectively with the peripheral benzodiazepine receptor (PBR).
2008-05-13 GO:0048228 actin cortical patch distribution Added DEFINITION The processes that establish the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells.
2008-05-13 GO:0051666 actin cortical patch localization Added DEFINITION The processes by which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
2008-05-13 GO:0003780 actin cross-linking activity Added DEFINITION OBSOLETE. Interacting selectively with two actin filaments to anchor them together.
2008-05-13 GO:0051764 actin crosslink formation Added DEFINITION The process by which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.
2008-05-13 GO:0015629 actin cytoskeleton Added DEFINITION The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
2008-05-13 GO:0030036 actin cytoskeleton organization Added DEFINITION A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2008-05-13 GO:0031532 actin cytoskeleton reorganization Added DEFINITION Dynamic structural changes to the assembly and arrangement of the actin cytoskeleton, comprising actin filaments and their associated proteins.
2008-05-13 GO:0003787 actin depolymerizing activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0005884 actin filament Added DEFINITION A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
2008-05-13 GO:0051015 actin filament binding Added DEFINITION Interacting selectively with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
2008-05-13 GO:0032432 actin filament bundle Added DEFINITION An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
2008-05-13 GO:0051017 actin filament bundle assembly Added DEFINITION The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
2008-05-13 GO:0051693 actin filament capping Added DEFINITION The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
2008-05-13 GO:0030042 actin filament depolymerization Added DEFINITION Disassembly of actin filaments by the removal of actin monomers from a filament.
2008-05-13 GO:0030043 actin filament fragmentation Added DEFINITION The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.
2008-05-13 GO:0051639 actin filament network formation Added DEFINITION The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.
2008-05-13 GO:0007015 actin filament organization Added DEFINITION Control of the spatial distribution of actin filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
2008-05-13 GO:0030041 actin filament polymerization Added DEFINITION Assembly of actin filaments by the addition of actin monomers to a filament.
2008-05-13 GO:0030037 actin filament reorganization involved in cell cycle Added DEFINITION The cell cycle process whereby rearrangement of the spatial distribution of actin filaments and associated proteins occurs.
2008-05-13 GO:0051014 actin filament severing Added DEFINITION The process by which an actin filament is broken down into smaller filaments.
2008-05-13 GO:0003789 actin filament severing activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0051695 actin filament uncapping Added DEFINITION The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
2008-05-13 GO:0030048 actin filament-based movement Added DEFINITION Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
2008-05-13 GO:0030029 actin filament-based process Added DEFINITION Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.
2008-05-13 GO:0033392 actin homodimerization activity Added DEFINITION Interacting selectively with an identical actin monomer to form a homodimer.
2008-05-13 GO:0003786 actin lateral binding Added DEFINITION Interacting selectively with an actin filament along its length.
2008-05-13 GO:0030047 actin modification Added DEFINITION Covalent modification of an actin molecule.
2008-05-13 GO:0003790 actin modulating activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0003785 actin monomer binding Added DEFINITION Interacting selectively with monomeric actin, also known as G-actin.
2008-05-13 GO:0003788 actin monomer sequestering activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0045010 actin nucleation Added DEFINITION The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
2008-05-13 GO:0031289 actin phosphorylation Added DEFINITION The transfer of one or more phosphate groups to an actin molecule.
2008-05-13 GO:0008154 actin polymerization or depolymerization Added DEFINITION Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.
2008-05-13 GO:0008651 actin polymerizing activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0031002 actin rod Added DEFINITION A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Found in the germinating spores of Dictyostelium discoideum.
2008-05-13 GO:0031247 actin rod assembly Added DEFINITION The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules.
2008-05-13 GO:0031003 actin tubule Added DEFINITION A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.
2008-05-13 GO:0030898 actin-dependent ATPase activity Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, requiring the presence of an actin filament to accelerate release of ADP and phosphate.
2008-05-13 GO:0003856 3-dehydroquinate synthase activity Added DEFINITION Catalysis of the reaction: 3-deoxy-arabino-heptulosonate 7-phosphate = 3-dehydroquinate + phosphate.
2008-05-13 GO:0046565 3-dehydroshikimate dehydratase activity Added DEFINITION Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate (protocatechuate) + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.
2008-05-13 GO:0047560 3-dehydrosphinganine reductase activity Added DEFINITION Catalysis of the reaction: sphinganine + NADP+ = 3-dehydrosphinganine + NADPH + H+.
2008-05-13 GO:0008689 3-demethylubiquinone-9 3-O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.
2008-05-13 GO:0033937 3-deoxy-2-octulosonidase activity Added DEFINITION Catalysis of the reaction: endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.
2008-05-13 GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity Added DEFINITION Catalysis of the reaction: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate.
2008-05-13 GO:0008676 3-deoxy-8-phosphooctulonate synthase activity Added DEFINITION Catalysis of the reaction: phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.
2008-05-13 GO:0047439 3-deoxy-D-manno-octulosonate aldolase activity Added DEFINITION Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.
2008-05-13 GO:0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity Added DEFINITION Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.
2008-05-13 GO:0019143 3-deoxy-manno-octulosonate-8-phosphatase activity Added DEFINITION Catalysis of the reaction: 3-deoxy-D-manno-octulosonate 8-phosphate + H2O = 3-deoxy-D-manno-octulosonate + phosphate.
2008-05-13 GO:0050534 3-deoxyoctulosonase activity Added DEFINITION Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.
2008-05-13 GO:0050441 3-ethylmalate synthase activity Added DEFINITION Catalysis of the reaction: butanoyl-CoA + H2O + glyoxylate = 3-ethylmalate + CoA .
2008-05-13 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity Added DEFINITION Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.
2008-05-13 GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
2008-05-13 GO:0047431 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methylpyridine-4,5-dicarboxylate = CO2 + 3-hydroxy-2-methylpyridine-5-carboxylate.
2008-05-13 GO:0047081 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + NAD(P)H + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NAD(P)+ + 2-(acetamidomethylene)succinate.
2008-05-13 GO:0050586 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methyl-1H-quinolin-4-one + O2 = N-acetylanthranilate + CO.
2008-05-13 GO:0047445 3-hydroxy-3-isohexenylglutaryl-CoA lyase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = acetate + 7-methyl-3-oxooctanoyl-CoA.
2008-05-13 GO:0047078 3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.
2008-05-13 GO:0018812 3-hydroxyacyl-CoA dehydratase activity Added DEFINITION Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).
2008-05-13 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+.
2008-05-13 GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: CH3-CHOH-CH2-[CH2]n-CO-[acyl-carrier protein] = H2O + CH3-CH-CH-[CH2]n-CO-[acyl-carrier protein].
2008-05-13 GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2008-05-13 GO:0030767 3-hydroxyanthranilate 4-C-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate.
2008-05-13 GO:0047561 3-hydroxyanthranilate oxidase activity Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2.
2008-05-13 GO:0047562 3-hydroxyaspartate aldolase activity Added DEFINITION Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = glycine + glyoxylate.
2008-05-13 GO:0047563 3-hydroxybenzoate 2-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxybenzoate + donor-H2 + O2 = 2,3-dihydroxybenzoate + acceptor + H2O.
2008-05-13 GO:0018668 3-hydroxybenzoate 4-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxybenzoate + NADPH + H+ + O2 = 3,4-dihydroxybenzoate + NADP+ + H2O.
2008-05-13 GO:0018669 3-hydroxybenzoate 6-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxybenzoate + NADH + H+ + O2 = 2,5-dihydroxybenzoate + NAD+ + H2O.
2008-05-13 GO:0018921 3-hydroxybenzyl alcohol metabolic process Added DEFINITION The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum.
2008-05-13 GO:0047048 3-hydroxybenzyl-alcohol dehydrogenase activity Added DEFINITION Catalysis of the reaction: NADP+ + 3-hydroxybenzyl alcohol = NADPH + H+ + 3-hydroxybenzaldehyde.
2008-05-13 GO:0003858 3-hydroxybutyrate dehydrogenase activity Added DEFINITION Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH + H+.
2008-05-13 GO:0003859 3-hydroxybutyryl-CoA dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O.
2008-05-13 GO:0008691 3-hydroxybutyryl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.
2008-05-13 GO:0008692 3-hydroxybutyryl-CoA epimerase activity Added DEFINITION Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.
2008-05-13 GO:0018712 3-hydroxybutyryl-CoA thiolase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.
2008-05-13 GO:0047564 3-hydroxycyclohexanone dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxycyclohexanone + acceptor = cyclohexane-1,3-dione + reduced acceptor.
2008-05-13 GO:0008693 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O.
2008-05-13 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
2008-05-13 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity Added DEFINITION Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.
2008-05-13 GO:0047155 3-hydroxymethylcephem carbamoyltransferase activity Added DEFINITION Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem.
2008-05-13 GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein].
2008-05-13 GO:0004317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity Added DEFINITION Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O.
2008-05-13 GO:0015551 3-hydroxyphenyl propanoate transmembrane transporter activity Added DEFINITION Catalysis of the transfer of 3-hydroxyphenyl propanoate from one side of the membrane to the other.
2008-05-13 GO:0015731 3-hydroxyphenyl propanoate transport Added DEFINITION The directed movement of 3-hydroxyphenyl propanoate into, out of, within or between cells.
2008-05-13 GO:0015540 3-hydroxyphenyl propionate:hydrogen ion symporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).
2008-05-13 GO:0047094 3-hydroxyphenylacetate 6-hydroxylase activity Added DEFINITION Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.
2008-05-13 GO:0033275 actin-myosin filament sliding Added DEFINITION The sliding movement of actin thin filaments and myosin thick filaments past each other.
2008-05-13 GO:0008129 actinidain activity Added DEFINITION Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'.
2008-05-13 GO:0042805 actinin binding Added DEFINITION Interacting selectively with actinin, any member of a family of proteins that crosslink F-actin.
2008-05-13 GO:0034304 actinomycete-type spore formation Added DEFINITION The process by which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.
2008-05-13 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) Added DEFINITION A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.
2008-05-13 GO:0031278 alpha-1,2-galactosyltransferase activity Added DEFINITION Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.
2008-05-13 GO:0000026 alpha-1,2-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.
2008-05-13 GO:0001962 alpha-1,3-galactosyltransferase activity Added DEFINITION Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,3-linkage.
2008-05-13 GO:0047657 alpha-1,3-glucan synthase activity Added DEFINITION Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.
2008-05-13 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2 = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2.
2008-05-13 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.
2008-05-13 GO:0000033 alpha-1,3-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,3-linkage.
2008-05-13 GO:0033201 alpha-1,4-glucan synthase activity Added DEFINITION Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.
2008-05-13 GO:0047211 alpha-1,4-glucan-protein synthase (ADP-forming) activity Added DEFINITION Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP.
2008-05-13 GO:0047210 alpha-1,4-glucan-protein synthase (UDP-forming) activity Added DEFINITION Catalysis of the reaction: protein + UDP-D-glucose = alpha-D-glucosyl-protein + UDP.
2008-05-13 GO:0051751 alpha-1,4-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,4-linkage.
2008-05-13 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity Added DEFINITION Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.
2008-05-13 GO:0047253 alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.
2008-05-13 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors.
2008-05-13 GO:0008455 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.
2008-05-13 GO:0000009 alpha-1,6-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,6-linkage.
2008-05-13 GO:0000136 alpha-1,6-mannosyltransferase complex Added DEFINITION A large, multiprotein complex with alpha-1,6 mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.
2008-05-13 GO:0019923 alpha-1-microglobulin-chromophore linkage Added DEFINITION The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds.
2008-05-13 GO:0031691 alpha-1A adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-1A adrenergic receptor.
2008-05-13 GO:0031692 alpha-1B adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-1B adrenergic receptor.
2008-05-13 GO:0031693 alpha-1D adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-1D adrenergic receptor.
2008-05-13 GO:0016975 alpha-2 macroglobulin Added DEFINITION OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates.
2008-05-13 GO:0016964 alpha-2 macroglobulin receptor activity Added DEFINITION Combining with an alpha-2 macroglobulin to initiate a change in cell activity.
2008-05-13 GO:0016963 alpha-2 macroglobulin receptor-associated protein activity Added DEFINITION OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains.
2008-05-13 GO:0031694 alpha-2A adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-2A adrenergic receptor.
2008-05-13 GO:0031695 alpha-2B adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-2B adrenergic receptor.
2008-05-13 GO:0031696 alpha-2C adrenergic receptor binding Added DEFINITION Interacting selectively with an alpha-2C adrenergic receptor.
2008-05-13 GO:0051393 alpha-actinin binding Added DEFINITION Interacting selectively with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
2008-05-13 GO:0033953 alpha-agarase activity Added DEFINITION Catalysis of the reaction: endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.
2008-05-13 GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Added DEFINITION An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
2008-05-13 GO:0043289 apocarotenoid biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.
2008-05-13 GO:0043290 apocarotenoid catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
2008-05-13 GO:0043288 apocarotenoid metabolic process Added DEFINITION The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
2008-05-13 GO:0005320 apolipoprotein Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0034186 apolipoprotein A-I binding Added DEFINITION Interacting selectively with apolipoprotein A-I.
2008-05-13 GO:0034188 apolipoprotein A-I receptor activity Added DEFINITION Combining with apolipoprotein A-I to initiate a change in cell activity.
2008-05-13 GO:0034191 apolipoprotein A-I receptor binding Added DEFINITION Interacting selectively with an apolipoprotein A-I receptor.
2008-05-13 GO:0030895 apolipoprotein B mRNA editing enzyme complex Added DEFINITION Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).
2008-05-13 GO:0034185 apolipoprotein binding Added DEFINITION Interacting selectively with an apolipoprotein, the protein component of a lipoprotein complex.
2008-05-13 GO:0034187 apolipoprotein E binding Added DEFINITION Interacting selectively with apolipoprotein E.
2008-05-13 GO:0030227 apolipoprotein E receptor activity Added DEFINITION Combining with apolipoprotein E to initiate a change in cell activity.
2008-05-13 GO:0050749 apolipoprotein E receptor binding Added DEFINITION Interacting selectively with an apolipoprotein E receptor.
2008-05-13 GO:0030226 apolipoprotein receptor activity Added DEFINITION Combining with an apolipoprotein, the protein component of a lipoprotein, to initiate a change in cell activity.
2008-05-13 GO:0034190 apolipoprotein receptor binding Added DEFINITION Interacting selectively with an apolipoprotein receptor.
2008-05-13 GO:0018989 apolysis Added DEFINITION The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.
2008-05-13 GO:0048046 apoplast Added DEFINITION The protoplasts of cells in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2008-05-13 GO:0015283 apoptogenic cytochrome c release channel activity Added DEFINITION OBSOLETE.
2008-05-13 GO:0006915 apoptotic process Added DEFINITION A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface.
2008-05-13 GO:0016506 apoptosis activator activity Added DEFINITION OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.
2008-05-13 GO:0008189 apoptosis inhibitor activity Added DEFINITION OBSOLETE. The function held by products which directly block any step in the process of apoptosis.
2008-05-13 GO:0060057 apoptotic process involved in mammary gland involution Added DEFINITION The form of programmed cell death that triggers the activity of proteolytic caspases, whose actions dismantle the mammary epithelial cells resulting in their death.
2008-05-13 GO:0016329 apoptosis regulator activity Added DEFINITION OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.
2008-05-13 GO:0043293 apoptosome Added DEFINITION A multisubunit protein complex involved in the activation of apoptosis. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
2008-05-13 GO:0043277 apoptotic cell clearance Added DEFINITION The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
2008-05-13 GO:0030263 apoptotic chromosome condensation Added DEFINITION The compaction of chromatin during apoptosis.
2008-05-13 GO:0008637 apoptotic mitochondrial changes Added DEFINITION The morphological and physiological alterations undergone by mitochondria during apoptosis.
2008-05-13 GO:0030262 apoptotic nuclear changes Added DEFINITION The morphological and physiological alterations undergone by the nucleus during apoptosis.
2008-05-13 GO:0008632 apoptotic program Added DEFINITION The intracellular signaling cascade that results when a cell is triggered to undergo apoptosis.
2008-05-13 GO:0048736 appendage development Added DEFINITION The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism. For example a limb or a branch.
2008-05-13 GO:0035107 appendage morphogenesis Added DEFINITION The process by which the anatomical structures of appendages are generated and organized. Morphogenesis pertains to the creation of form. An appendage is an organ or part that is attached to the trunk of an organism. For example a limb or a branch.
2008-05-13 GO:0035285 appendage segmentation Added DEFINITION Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.
2008-05-13 GO:0007475 apposition of dorsal and ventral imaginal disc-derived wing surfaces Added DEFINITION The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
2008-05-13 GO:0004050 apyrase activity Added DEFINITION OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate.
2008-05-13 GO:0050444 aquacobalamin reductase (NADPH) activity Added DEFINITION Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+.
2008-05-13 GO:0047138 aquacobalamin reductase activity Added DEFINITION Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+.
2008-05-13 GO:0034075 arabidiol synthase activity Added DEFINITION Catalysis of the reaction: oxidosqualene = arabidiol ((3S,13R,14R)-malabarica-17E,21-dien-3beta,14-diol).
2008-05-13 GO:0031222 arabinan catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of arabinan, a branched homopolymer of L-arabinose.
2008-05-13 GO:0046558 arabinan endo-1,5-alpha-L-arabinosidase activity Added DEFINITION Catalysis of the endohydrolysis of 1,5-alpha-arabinofuranosidic linkages in 1,5-arabinans.
2008-05-13 GO:0031221 arabinan metabolic process Added DEFINITION The chemical reactions and pathways involving arabinan, a branched homopolymer of L-arabinose.
2008-05-13 GO:0046233 3-hydroxyphenylacetate biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
2008-05-13 GO:0009265 2'-deoxyribonucleotide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.
2008-05-13 GO:0009394 2'-deoxyribonucleotide metabolic process Added DEFINITION The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety.
2008-05-13 GO:0018740 2'-hydroxybiphenyl-2-sulfinate desulfinase activity Added DEFINITION Catalysis of the reaction: 2-(2-hydroxyphenyl)benzenesulfinate + H2O = 2-hydroxybiphenyl + SO3(2-) (sulfite).
2008-05-13 GO:0047525 2'-hydroxydaidzein reductase activity Added DEFINITION Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzen + NADPH + H+.
2008-05-13 GO:0047526 2'-hydroxyisoflavone reductase activity Added DEFINITION Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.
2008-05-13 GO:0008665 2'-phosphotransferase activity Added DEFINITION Catalysis of the transfer of a phosphate group from one compound to the 2' position of another.
2008-05-13 GO:0018556 2,2',3-trihydroxybiphenyl dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).
2008-05-13 GO:0047432 2,2-dialkylglycine decarboxylase (pyruvate) activity Added DEFINITION Catalysis of the reaction: 2,2-dialkylglycine + pyruvate = dialkyl ketone + L-alanine + CO2.
2008-05-13 GO:0008666 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Added DEFINITION Catalysis of the reaction: succinyl-CoA + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.
2008-05-13 GO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Added DEFINITION Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; requires the cofactor 2,3-bisphosphoglycerate.
2008-05-13 GO:0046537 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Added DEFINITION Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate without requiring the cofactor 2,3-bisphosphoglycerate.
2008-05-13 GO:0047189 2,3-diaminopropionate N-oxalyltransferase activity Added DEFINITION Catalysis of the reaction: L-2,3-diaminopropanoate + oxalyl-CoA = N3-oxalyl-L-23-diaminopropanoate + CoA.
2008-05-13 GO:0008667 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydro-2,3-dihydroxybenzoate + NAD+ = 2,3-dihydroxybenzoate + NADH + H+.
2008-05-13 GO:0018542 2,3-dihydroxy DDT 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.
2008-05-13 GO:0018511 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity Added DEFINITION Catalysis of the reaction: cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD+ = 2,3-dihydroxy-p-cumate + NADH + H+.
2008-05-13 GO:0018498 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity Added DEFINITION Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.
2008-05-13 GO:0018563 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.
2008-05-13 GO:0018571 2,3-dihydroxy-p-cumate dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.
2008-05-13 GO:0047072 2,3-dihydroxybenzoate 2,3-dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + 2,3-dihydroxybenzoate = 2-carboxy-cis,cis-muconate.
2008-05-13 GO:0045133 2,3-dihydroxybenzoate 3,4-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 3-carboxy-2-hydroxymuconate semialdehyde.
2008-05-13 GO:0018790 2,3-dihydroxybenzoate decarboxylase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybenzoate + H+ = CO2 + catechol.
2008-05-13 GO:0047527 2,3-dihydroxybenzoate-serine ligase activity Added DEFINITION Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.
2008-05-13 GO:0043898 2,3-dihydroxybiphenyl 1,2-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.
2008-05-13 GO:0047528 2,3-dihydroxyindole 2,3-dioxygenase activity Added DEFINITION Catalysis of the reaction: 2,3-dihydroxyindole + O2 = anthranilate + CO2.
2008-05-13 GO:0043715 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity Added DEFINITION Catalysis of the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
2008-05-13 GO:0047529 2,3-dimethylmalate lyase activity Added DEFINITION Catalysis of the reaction: 2,3-dimethylmalate = propanoate + pyruvate.
2008-05-13 GO:0047073 2,4'-dihydroxyacetophenone dioxygenase activity Added DEFINITION Catalysis of the reaction: O2 + 2',4'-dihydroxyacetophenone = formate + p-hydroxybenzoate.
2008-05-13 GO:0046227 2,4,5-trichlorophenoxyacetic acid biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.
2008-05-13 GO:0046228 2,4,5-trichlorophenoxyacetic acid catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.
2008-05-13 GO:0018980 2,4,5-trichlorophenoxyacetic acid metabolic process Added DEFINITION The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.
2008-05-13 GO:0018584 2,4,5-trichlorophenoxyacetic acid oxygenase activity Added DEFINITION Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.
2008-05-13 GO:0046255 2,4,6-trinitrotoluene biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene.
2008-05-13 GO:0046256 2,4,6-trinitrotoluene catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.
2008-05-13 GO:0018974 2,4,6-trinitrotoluene metabolic process Added DEFINITION The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.
2008-05-13 GO:0047530 2,4-diaminopentanoate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+.
2008-05-13 GO:0046297 2,4-dichlorobenzoate biosynthetic process Added DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
2008-05-13 GO:0046298 2,4-dichlorobenzoate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
2008-05-13 GO:0018898 2,4-dichlorobenzoate metabolic process Added DEFINITION The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
2008-05-13 GO:0018857 2,4-dichlorobenzoate-CoA ligase activity Added DEFINITION Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.
2008-05-13 GO:0018516 2,4-dichlorobenzoyl-CoA reductase activity Added DEFINITION Catalysis of the reaction: 4-chlorobenzoyl-CoA + NADP+ + HCl = 2,4-dichlorobenzoyl-CoA + NADPH + H+.
2008-05-13 GO:0018666 2,4-dichlorophenol 6-monooxygenase activity Added DEFINITION Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.
2008-05-13 GO:0015792 arabinitol transport Added DEFINITION The directed movement of arabitol into, out of, within or between cells. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
2008-05-13 GO:0031218 arabinogalactan endo-1,4-beta-galactosidase activity Added DEFINITION Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in arabinogalactans.
2008-05-13 GO:0001761 beta-alanine transmembrane transporter activity Added DEFINITION Catalysis of the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.
2008-05-13 GO:0001762 beta-alanine transport Added DEFINITION The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of, within or between cells.
2008-05-13 GO:0016223 beta-alanine-pyruvate transaminase activity Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.
2008-05-13 GO:0047697 beta-alanopine dehydrogenase activity Added DEFINITION Catalysis of the reaction: beta-alanopine + NAD+ + H2O = beta-alanine + pyruvate + NADH.
2008-05-13 GO:0047698 beta-alanyl-CoA ammonia-lyase activity Added DEFINITION Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3.
2008-05-13 GO:0003832 beta-alanyl-dopamine hydrolase activity Added DEFINITION Catalysis of the conversion of beta-alanyl dopamine to dopamine (3,4-dihydroxyphenylethylamine).
2008-05-13 GO:0003833 beta-alanyl-dopamine synthase activity Added DEFINITION Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine).
2008-05-13 GO:0031964 beta-alanyl-histamine hydrolase activity Added DEFINITION Catalysis of the conversion of beta-alanyl-histamine to histamine.
2008-05-13 GO:0016161 beta-amylase activity Added DEFINITION Catalysis of the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.
2008-05-13 GO:0001540 beta-amyloid binding Added DEFINITION Interacting selectively with beta-amyloid peptide/protein and/or its precursor.
2008-05-13 GO:0034205 beta-amyloid formation Added DEFINITION The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
2008-05-13 GO:0050435 beta-amyloid metabolic process Added DEFINITION The chemical reactions and pathways involving beta-amyloid, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).
2008-05-13 GO:0042300 beta-amyrin synthase activity Added DEFINITION Catalysis of the cyclization and rearrangement of 2,3-oxidosqualene into beta-amyrin.
2008-05-13 GO:0033956 beta-apiosyl-beta-glucosidase activity Added DEFINITION Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.
2008-05-13 GO:0047406 beta-aspartyl-N-acetylglucosaminidase activity Added DEFINITION Catalysis of the reaction: H2O + 1-beta-aspartyl-N-acetyl-D-glucosaminylamine = L-asparagine + N-acetyl-D-glucosamine.
2008-05-13 GO:0008798 beta-aspartyl-peptidase activity Added DEFINITION Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.
2008-05-13 GO:0003834 beta-carotene 15,15'-monooxygenase activity Added DEFINITION Catalysis of the reaction: beta-carotene + O2 = 2 retinal.
2008-05-13 GO:0042411 beta-carotene hydroxylase activity Added DEFINITION Catalysis of the hydroxylation of both beta rings of beta-carotene to form zeaxanthine.
2008-05-13 GO:0008013 beta-catenin binding Added DEFINITION Interacting selectively with the beta subunit of the catenin complex.
2008-05-13 GO:0030877 beta-catenin destruction complex Added DEFINITION A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
2008-05-13 GO:0050448 beta-cyclopiazonate dehydrogenase activity Added DEFINITION Catalysis of the reaction: beta-cyclopiazonate + acceptor = alpha-cyclopiazonate + reduced acceptor.
2008-05-13 GO:0033907 beta-D-fucosidase activity Added DEFINITION Catalysis of the reaction: hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.
2008-05-13 GO:0047699 beta-diketone hydrolase activity Added DEFINITION Catalysis of the reaction: nonane-4,6-dione + H2O = pentan-2-one + butanoate.
2008-05-13 GO:0031626 beta-endorphin binding Added DEFINITION Interacting selectively with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.
2008-05-13 GO:0004979 beta-endorphin receptor activity Added DEFINITION Combining with beta-endorphin to initiate a change in cell activity.
2008-05-13 GO:0004564 beta-fructofuranosidase activity Added DEFINITION Catalysis of the hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.
2008-05-13 GO:0033944 beta-galactofuranosidase activity Added DEFINITION Catalysis of the reaction: hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.
2008-05-13 GO:0004565 beta-galactosidase activity Added DEFINITION Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.
2008-05-13 GO:0009341 beta-galactosidase complex Added DEFINITION A multimeric enzyme complex that in E. coli is an heterooctamer made up of four alpha subunits and four beta subunits. Catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.
2008-05-13 GO:0017030 beta-galactosidase stabilization activity Added DEFINITION OBSOLETE. Stabilization of the structure of beta-galactosidase.
2008-05-13 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Added DEFINITION Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R.
2008-05-13 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity Added DEFINITION Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine.
2008-05-13 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide.
2008-05-13 GO:0051274 beta-glucan biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of beta-glucans.
2008-05-13 GO:0051275 beta-glucan catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of beta-glucans.
2008-05-13 GO:0051273 beta-glucan metabolic process Added DEFINITION The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.
2008-05-13 GO:0015160 beta-glucan transmembrane transporter activity Added DEFINITION Catalysis of the transfer of beta-glucans from one side of the membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
2008-05-13 GO:0015775 beta-glucan transport Added DEFINITION The directed movement of beta-glucans into, out of, within or between cells. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
2008-05-13 GO:0015441 beta-glucan-transporting ATPase activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).
2008-05-13 GO:0047201 beta-glucogallin O-galloyltransferase activity Added DEFINITION Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1-O,6-O-digalloyl-beta-D-glucose + beta-D-glucose.
2008-05-13 GO:0047176 beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity Added DEFINITION Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + beta-D-glucose.
2008-05-13 GO:0008422 beta-glucosidase activity Added DEFINITION Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
2008-05-13 GO:0047700 beta-glucoside kinase activity Added DEFINITION Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.
2008-05-13 GO:0015573 beta-glucoside transmembrane transporter activity Added DEFINITION Catalysis of the transfer of beta-glucosides from one side of the membrane to the other. Beta-glucosides are glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
2008-05-13 GO:0047615 actinomycin lactonase activity Added DEFINITION Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.
2008-05-13 GO:0019227 neuronal action potential propagation Added DEFINITION A neurological process that causes the sequential depolarization of a neuron's cell membrane along an axon.
2008-05-13 GO:0006924 activation-induced cell death of T cells Added DEFINITION The process of apoptosis in activated T cells.
2008-05-13 GO:0050798 activated T cell proliferation Added DEFINITION The expansion of a T cell population following activation by an antigenic stimulus.
2008-05-13 GO:0032397 activating MHC class I receptor activity Added DEFINITION Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
2008-05-13 GO:0007190 activation of adenylate cyclase activity Added DEFINITION Any process that initiates the activity of the inactive enzyme adenylate cyclase.
2008-05-13 GO:0051488 activation of anaphase-promoting complex activity Added DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex.
2008-05-13 GO:0051487 activation of anaphase-promoting complex activity involved in meiotic cell cycle Added DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the meiotic cell cycle.
2008-05-13 GO:0007092 activation of mitotic anaphase-promoting complex activity Added DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the mitotic cell cycle.
2008-05-13 GO:0032857 activation of ARF GTPase activity Added DEFINITION Any process that initiates the activity of the inactive enzyme ARF GTPase through the replacement of GDP by GTP.
2008-05-13 GO:0051519 activation of bipolar cell growth Added DEFINITION Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.
2008-05-13 GO:0002543 activation of blood coagulation via clotting cascade Added DEFINITION Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.
2008-05-13 GO:0032864 activation of Cdc42 GTPase activity Added DEFINITION Any process that initiates the activity of the inactive GTPase Cdc42 through the replacement of GDP by GTP.
2008-05-13 GO:0032793 positive regulation of CREB transcription factor activity Added DEFINITION Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.
2008-05-13 GO:0007239 activation of Hog1 Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0002253 activation of immune response Added DEFINITION Any process that initiates an immune response.
2008-05-13 GO:0002218 activation of innate immune response Added DEFINITION Any process that initiates an innate immune response.
2008-05-13 GO:0010531 activation of JAK1 kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-05-13 GO:0042977 activation of JAK2 kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
2008-05-13 GO:0042976 activation of Janus kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-05-13 GO:0007257 activation of JUN kinase activity Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK).
2008-05-13 GO:0007256 activation of JNKK activity Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
2008-05-13 GO:0042655 activation of JNKKK activity Added DEFINITION The initiation of the activity of the inactive enzyme JUN kinase kinase kinase activity in response to phosphorylation by a member of the MAP kinase kinase kinase kinase (MAPKKKK) family or another upstream kinase.
2008-05-13 GO:0030456 activation of MAPK (mating sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0007247 activation of MAPK (mating sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.
2008-05-13 GO:0000193 activation of MAPK (pseudohyphal growth) Added DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.
2008-05-13 GO:0000187 activation of MAPK activity Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK.
2008-05-13 GO:0000199 activation of MAPK activity involved in cell wall organization or biogenesis Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
2008-05-13 GO:0000169 activation of MAPK activity involved in osmosensory signaling pathway Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase activity during osmolarity sensing.
2008-05-13 GO:0030439 activation of MAPK during sporulation (sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0000205 activation of MAPK during sporulation (sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2008-05-13 GO:0030457 activation of MAPKK (mating sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0007246 activation of MAPKK (mating sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces.
2008-05-13 GO:0000192 activation of MAPKK (pseudohyphal growth) Added DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth.
2008-05-13 GO:0000186 activation of MAPKK activity Added DEFINITION The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK.
2008-05-13 GO:0000198 activation of MAPKK activity involved in cell wall organization or biogenesis Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
2008-05-13 GO:0000168 activation of MAPKK activity involved in osmosensory signaling pathway Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase during osmolarity sensing.
2008-05-13 GO:0030440 activation of MAPKK during sporulation (sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0000204 activation of MAPKK during sporulation (sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2008-05-13 GO:0030458 activation of MAPKKK (mating sensu Fungi) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2008-05-13 GO:0007245 activation of MAPKKK (mating sensu Saccharomyces) Added DEFINITION OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.
2008-05-13 GO:0000191 activation of MAPKKK (pseudohyphal growth) Added DEFINITION OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth.
2008-05-13 GO:0000185 activation of MAPKKK activity Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase.
2008-05-13 GO:0000197 activation of MAPKKK activity involved in cell wall organization or biogenesis Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
2008-05-13 GO:0000167 activation of MAPKKK activity involved in osmosensory signaling pathway Added DEFINITION Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during osmolarity sensing.
2008-05-13 GO:0019610 3-hydroxyphenylacetate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
2008-05-13 GO:0019609 3-hydroxyphenylacetate metabolic process Added DEFINITION The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
2008-05-13 GO:0042920 3-hydroxyphenylpropionic acid transport Added DEFINITION The directed movement of 3-hydroxyphenylpropionic acid into, out of, within or between cells.
2008-05-13 GO:0042926 3-hydroxyphenylpropionic acid transporter activity Added DEFINITION Enables the directed movement of 3-hydroxyphenylpropionic acid into, out of, within or between cells.
2008-05-13 GO:0018464 3-hydroxypimeloyl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-hydroxypimeloyl-CoA + NAD+ = 3-oxopimeloyl-CoA + NADH + H+.
2008-05-13 GO:0047565 3-hydroxypropionate dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: 3-hydroxypropanoate + NAD+ = 3-oxopropanoate + NADH + H+.
2008-05-13 GO:0018854 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity Added DEFINITION Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
2008-05-13 GO:0003861 3-isopropylmalate dehydratase activity Added DEFINITION Catalysis of the reaction: 3-isopropylmalate = 2-isopropylmaleate + H2O.
2008-05-13 GO:0009316 3-isopropylmalate dehydratase complex Added DEFINITION A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
2008-05-13 GO:0003862 3-isopropylmalate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.
2008-05-13 GO:0000253 3-keto sterol reductase activity Added DEFINITION Catalysis of the reaction: 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + NADPH + H+.
2008-05-13 GO:0043720 3-keto-5-aminohexanoate cleavage activity Added DEFINITION Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.
2008-05-13 GO:0006666 3-keto-sphinganine metabolic process Added DEFINITION The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
2008-05-13 GO:0050576 3-keto-steroid reductase activity Added DEFINITION Catalysis of the reaction: 4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NADP+ = 4-alpha-methyl-5-alpha-cholest-7-en-3-one + NADPH + H+.
2008-05-13 GO:0048258 3-ketoglucose-reductase activity Added DEFINITION Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.
2008-05-13 GO:0018713 3-ketopimelyl-CoA thiolase activity Added DEFINITION Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.
2008-05-13 GO:0047566 3-ketovalidoxylamine C-N-lyase activity Added DEFINITION Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one.
2008-05-13 GO:0016784 3-mercaptopyruvate sulfurtransferase activity Added DEFINITION Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
2008-05-13 GO:0018653 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity Added DEFINITION Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.
2008-05-13 GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity Added DEFINITION Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.
2008-05-13 GO:0043807 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity Added DEFINITION Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin.
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