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GO Term History: Displaying 462 audit records for all terms for the date 2008-03-11

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2008-03-11 GO:0010567 regulation of ketone catabolic process Added TERM regulation of ketone catabolic process
2008-03-11 GO:0030436 asexual sporulation Updated TERM asexual sporulation
2008-03-11 GO:0030437 ascospore formation Updated TERM ascospore formation
2008-03-11 GO:0030476 ascospore wall assembly Updated TERM ascospore wall assembly
2008-03-11 GO:0010562 positive regulation of phosphorus metabolic process Added TERM positive regulation of phosphorus metabolic process
2008-03-11 GO:0010563 negative regulation of phosphorus metabolic process Added TERM negative regulation of phosphorus metabolic process
2008-03-11 GO:0010564 regulation of cell cycle process Added TERM regulation of cell cycle process
2008-03-11 GO:0010565 regulation of cellular ketone metabolic process Added TERM regulation of ketone metabolic process
2008-03-11 GO:0010566 regulation of ketone biosynthetic process Added TERM regulation of ketone biosynthetic process
2008-03-11 GO:0034294 sexual spore wall assembly Added TERM sexual spore wall assembly
2008-03-11 GO:0034295 basidiospore formation Added TERM basidiospore formation
2008-03-11 GO:0034296 zygospore formation Added TERM zygospore formation
2008-03-11 GO:0034297 oidium formation Added TERM oidium formation
2008-03-11 GO:0034298 arthrospore formation Added TERM arthrospore formation
2008-03-11 GO:0034299 reproductive blastospore formation Added TERM blastospore formation
2008-03-11 GO:0034300 sporangiospore formation Added TERM sporangiospore formation
2008-03-11 GO:0034301 endospore formation Added TERM endospore formation
2008-03-11 GO:0034302 akinete formation Added TERM akinete formation
2008-03-11 GO:0034303 myxospore formation Added TERM myxospore formation
2008-03-11 GO:0034304 actinomycete-type spore formation Added TERM actinomycete-type spore formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added TERM regulation of asexual sporulation
2008-03-11 GO:0034306 regulation of sexual sporulation Added TERM regulation of sexual sporulation
2008-03-11 GO:0034307 regulation of ascospore formation Added TERM regulation of ascospore formation
2008-03-11 GO:0034308 primary alcohol metabolic process Added TERM monohydric alcohol metabolic process
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added TERM monohydric alcohol biosynthetic process
2008-03-11 GO:0034310 primary alcohol catabolic process Added TERM monohydric alcohol catabolic process
2008-03-11 GO:0034311 diol metabolic process Added TERM diol metabolic process
2008-03-11 GO:0034312 diol biosynthetic process Added TERM diol biosynthetic process
2008-03-11 GO:0034313 diol catabolic process Added TERM diol catabolic process
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Updated TERM ascospore wall chitin biosynthetic process
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Updated TERM ascospore wall chitin metabolic process
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Updated TERM regulation of ascospore wall chitin biosynthetic process
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Updated TERM ascospore wall chitin catabolic process
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Updated TERM regulation of ascospore wall chitin catabolic process
2008-03-11 GO:0031321 ascospore-type prospore assembly Updated TERM ascospore-type prospore formation
2008-03-11 GO:0031322 ascospore-type prospore-specific spindle pole body remodeling Updated TERM ascospore-type prospore-specific spindle pole body modification
2008-03-11 GO:0032120 ascospore-type prospore membrane assembly Updated TERM ascospore-type prospore membrane formation
2008-03-11 GO:0042243 asexual spore wall assembly Updated TERM asexual spore wall assembly
2008-03-11 GO:0042763 intracellular immature spore Updated TERM intracellular immature spore
2008-03-11 GO:0042764 ascospore-type prospore Updated TERM ascospore-type prospore
2008-03-11 GO:0034293 sexual sporulation Added TERM sexual sporulation
2008-03-11 GO:0034220 ion transmembrane transport Added DEFINITION The process whereby an ion is transported from one side of a membrane to the other.
2008-03-11 GO:0034274 Atg12-Atg5-Atg16 complex Added DEFINITION A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.
2008-03-11 GO:0034273 ATG1/UKL1 signaling complex Added DEFINITION A protein complex that contains a protein kinase and is required for the autophagosome formation. In budding yeast this complex consists of the kinase Atg1p, Atg13p and Atg17p.
2008-03-11 GO:0004931 extracellular ATP-gated cation channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0006914 autophagy Updated DEFINITION The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
2008-03-11 GO:0034262 autophagy in response to cellular starvation Added DEFINITION The process by which cells digest parts of their own cytoplasm in response to deprivation of nourishment.
2008-03-11 GO:0034263 autophagy in response to ER overload Added DEFINITION The process by which cells digest parts of their own cytoplasm in response to the accumulation of misfolded proteins in the endoplasmic reticulum.
2008-03-11 GO:0030183 B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a B cell.
2008-03-11 GO:0047514 1,3-beta-D-glucan phosphorylase activity Updated DEFINITION Catalysis of the reaction: 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.
2008-03-11 GO:0047515 1,3-beta-oligoglucan phosphorylase activity Updated DEFINITION Catalysis of the reaction: oligomeric 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.
2008-03-11 GO:0005943 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex Updated DEFINITION A heterodimeric protein complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic Class IA phosphoinositide 3-kinase (PI3K) subunit of 110-120 kDa and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.
2008-03-11 GO:0005944 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex Updated DEFINITION A heterodimeric protein complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic Class IB phosphoinositide 3-kinase (PI3K) subunit of 110-120 kDa and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.
2008-03-11 GO:0051166 2,5-dihydroxypyridine catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.
2008-03-11 GO:0047011 2-dehydropantolactone reductase (A-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-03-11 GO:0019141 2-dehydropantolactone reductase (B-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-03-11 GO:0043724 2-keto-3-deoxygalactonate aldolase activity Updated DEFINITION Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate.
2008-03-11 GO:0018167 protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine Updated DEFINITION The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.
2008-03-11 GO:0034035 purine ribonucleoside bisphosphate metabolic process Updated DEFINITION The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a glycosamine consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on its glycose moiety.
2008-03-11 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Added DEFINITION Combining with a purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2008-03-11 GO:0009198 pyrimidine deoxyribonucleoside diphosphate catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a glycosamine consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on its glycose moiety.
2008-03-11 GO:0034213 quinolinate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
2008-03-11 GO:0032482 Rab protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
2008-03-11 GO:0010533 regulation of activation of Janus kinase activity Added DEFINITION Any process that modulates the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-03-11 GO:0010532 regulation of activation of JAK1 kinase activity Added DEFINITION Any process that modulates the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-03-11 GO:0010534 regulation of activation of JAK2 kinase activity Added DEFINITION Any process that modulates the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
2008-03-11 GO:0034251 regulation of cellular amide catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
2008-03-11 GO:0034248 regulation of cellular amide metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.
2008-03-11 GO:0010522 regulation of calcium ion transport into cytosol Added DEFINITION Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
2008-03-11 GO:0034233 regulation of cell wall chitin catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.
2008-03-11 GO:0034222 regulation of cell wall chitin metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.
2008-03-11 GO:0003106 negative regulation of glomerular filtration by angiotensin Added DEFINITION The process by which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
2008-03-11 GO:0034239 regulation of macrophage fusion Added DEFINITION Any process that modulates the frequency, rate or extent of macrophage fusion.
2008-03-11 GO:0010549 regulation of membrane disassembly Added DEFINITION Any process that modulates the frequency, rate or extent of membrane disassembly.
2008-03-11 GO:0003078 regulation of natriuresis Added DEFINITION Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.
2008-03-11 GO:0010543 regulation of platelet activation Added DEFINITION Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
2008-03-11 GO:0010550 regulation of PSII associated light-harvesting complex II catabolic process Added DEFINITION Any process that modulates the catabolism of one or more components of the light-harvesting complex of photosystem II.
2008-03-11 GO:0060222 regulation of retinal cone cell fate commitment Added DEFINITION Any process that modulates the process whereby a cell becomes commited to a retinal cone cell fate. Retinal cone cell fate commitment is the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
2008-03-11 GO:0060224 regulation of retinal rod cell fate commitment Added DEFINITION Any process that modulates the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter Added DEFINITION Any process that modulates the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides, catalyzed by RNA polymerase II.
2008-03-11 GO:0014708 regulation of somitomeric trunk muscle development Updated DEFINITION Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.
2008-03-11 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter Added DEFINITION Any process that modulates the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter.
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of spore wall chitin.
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of spore wall chitin.
2008-03-11 GO:0060092 regulation of synaptic transmission, glycinergic Updated DEFINITION Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
2008-03-11 GO:0010548 regulation of thylakoid membrane disassembly Added DEFINITION Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.
2008-03-11 GO:0034225 regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation Added DEFINITION Modulation of the frequency, rate or extent of transcription from an from RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions.
2008-03-11 GO:0006450 regulation of translational fidelity Updated DEFINITION Any process that modulates the ability of the translational apparatus to interpret the genetic code.
2008-03-11 GO:0043561 regulation of translational initiation in response to osmotic stress Updated DEFINITION Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
2008-03-11 GO:0010528 regulation of transposition Added DEFINITION Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0010525 regulation of transposition, RNA-mediated Added DEFINITION Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
2008-03-11 GO:0034254 regulation of urea catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.
2008-03-11 GO:0034224 cellular response to zinc ion starvation Added DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.
2008-03-11 GO:0047026 androsterone dehydrogenase (A-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
2008-03-11 GO:0047042 androsterone dehydrogenase (B-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
2008-03-11 GO:0005945 6-phosphofructokinase complex Updated DEFINITION A protein complex that possesses 6-phosphofructokinase activity; homodimeric and allosteric homotetrameric forms are known.
2008-03-11 GO:0045193 acetylated low-density lipoprotein catabolic process Updated DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetylated low-density lipoproteins.
2008-03-11 GO:0010541 acropetal auxin transport Added DEFINITION The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.
2008-03-11 GO:0004284 acrosin activity Updated DEFINITION Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa.
2008-03-11 GO:0051488 activation of anaphase-promoting complex activity Updated DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex.
2008-03-11 GO:0051487 activation of anaphase-promoting complex activity involved in meiotic cell cycle Updated DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the meiotic cell cycle.
2008-03-11 GO:0007092 activation of mitotic anaphase-promoting complex activity Updated DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the mitotic cell cycle.
2008-03-11 GO:0010531 activation of JAK1 kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-03-11 GO:0032861 activation of Rap GTPase activity Updated DEFINITION Any process that initiates the activity of an inactive GTPase of the Rap family through the replacement of GDP by GTP.
2008-03-11 GO:0003996 acyl-CoA ligase activity Added DEFINITION Catalysis of the reaction: an acyl + ATP + CoASH = AMP + diphosphate + acyl-CoA.
2008-03-11 GO:0001609 G-protein coupled adenosine receptor activity Added DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2008-03-11 GO:0047380 ADP-dependent medium-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA.
2008-03-11 GO:0047379 ADP-dependent short-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA.
2008-03-11 GO:0002299 alpha-beta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0046632 alpha-beta T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-03-11 GO:0019561 anaerobic phenylalanine oxidation Added DEFINITION The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.
2008-03-11 GO:0048905 anterior lateral line neuromast mantle cell differentiation Updated DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2008-03-11 GO:0042895 antibiotic transporter activity Updated DEFINITION Enables the directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of, within or between cells.
2008-03-11 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway Updated DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2008-03-11 GO:0019546 arginine deiminase pathway Added DEFINITION The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.
2008-03-11 GO:0034255 regulation of urea metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.
2008-03-11 GO:0003117 regulation of vasoconstriction by circulating norepinephrine Updated DEFINITION Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.
2008-03-11 GO:0003125 regulation of vasodilation by circulating norepinephrine Updated DEFINITION Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.
2008-03-11 GO:0003126 regulation of vasodilation by neuronal norepinephrine Updated DEFINITION Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of norepinephrine released by nerve endings.
2008-03-11 GO:0010555 response to mannitol Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
2008-03-11 GO:0034201 response to oleic acid Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a oleate stimulus.
2008-03-11 GO:0046551 retinal cone cell fate commitment Updated DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0060221 retinal rod cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a retinal rod cell.
2008-03-11 GO:0060223 retinal rod cell fate commitment Added DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0033890 ribonuclease D activity Updated DEFINITION Catalysis of the reaction: exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
2008-03-11 GO:0033587 shikimate biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.
2008-03-11 GO:0034247 snoRNA splicing Added DEFINITION The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.
2008-03-11 GO:0065001 specification of axis polarity Added DEFINITION The pattern specification process by which the polarity of a body or organ axis is established and maintained.
2008-03-11 GO:0007055 spindle assembly involved in male meiosis II Updated DEFINITION The formation of the spindle during meiosis II of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208).
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of spore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal-type spores.
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of spore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal-type spores.
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Added DEFINITION The chemical reactions and pathways involving spore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal-type spores.
2008-03-11 GO:0034209 sterol acetylation Updated DEFINITION The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
2008-03-11 GO:0034210 sterol deacetylation Updated DEFINITION The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
2008-03-11 GO:0050309 sugar-terminal-phosphatase activity Updated DEFINITION Catalysis of the reaction: H2O + a sugar phosphate = a sugar + phosphate; an example is D-glucose 6-phosphate + H2O = D-glucose + phosphate.
2008-03-11 GO:0030217 T cell differentiation Updated DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2008-03-11 GO:0033077 T cell differentiation in thymus Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
2008-03-11 GO:0010521 telomerase inhibitor activity Added DEFINITION Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
2008-03-11 GO:0034215 thiamine:proton symporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamin(out) + H+(out) = thiamin(in) + H+(in).
2008-03-11 GO:0010547 thylakoid membrane disassembly Added DEFINITION The controlled breakdown of the thylakoid membrane in the context of a normal process.
2008-03-11 GO:0034219 carbohydrate transmembrane transport Added DEFINITION The process whereby a carbohydrate is transported from one side of a membrane to the other.
2008-03-11 GO:0046562 glucose oxidase activity Updated DEFINITION Catalysis of the reaction: a hexose + O2 = a hexno-1,5-lactone + H2O2; includes beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.
2008-03-11 GO:0015503 glutathione-regulated potassium exporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
2008-03-11 GO:0034235 GPI anchor binding Added DEFINITION Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
2008-03-11 GO:0048503 GPI anchor binding Updated DEFINITION OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
2008-03-11 GO:0051737 GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity Updated DEFINITION Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.
2008-03-11 GO:0060217 hemangioblast cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.
2008-03-11 GO:0002244 hematopoietic progenitor cell differentiation Updated DEFINITION The process whereby precursor cell type acquires the specialized features of a hemopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2008-03-11 GO:0060218 hematopoietic stem cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a hemopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
2008-03-11 GO:0015362 high affinity sodium:dicarboxylate symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0015678 high-affinity copper ion transport Added DEFINITION The directed, high-affinity movement of copper (Cu) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0015683 high-affinity ferric iron transport Added DEFINITION The directed, high-affinity movement of ferric (Fe(III) or Fe3+) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0008646 high-affinity hexose transport Added DEFINITION The directed, high-affinity movement of a hexose into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0005358 high-affinity hydrogen:glucose symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constituitive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0006827 high-affinity iron ion transmembrane transport Added DEFINITION The directed, high-affinity movement of iron (Fe) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0034216 high-affinity thiamine:proton symporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamin(out) + H+(out) = thiamin(in) + H+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0006830 high-affinity zinc ion transport Added DEFINITION The directed, high-affinity movement of zinc (Zn) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0000836 Hrd1p ubiquitin ligase complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
2008-03-11 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
2008-03-11 GO:0000496 base pairing Added DEFINITION Interacting selectively with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target nucleic acid molecule.
2008-03-11 GO:0000497 base pairing with DNA Added DEFINITION Interacting selectively with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.
2008-03-11 GO:0000499 base pairing with mRNA Added DEFINITION Interacting selectively with messenger ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target mRNA molecule.
2008-03-11 GO:0000498 base pairing with RNA Added DEFINITION Interacting selectively with ribonucleic acid (RNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target RNA molecule.
2008-03-11 GO:0000944 base pairing with rRNA Added DEFINITION Interacting selectively with ribosomal ribonucleic acid (rRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target rRNA molecule.
2008-03-11 GO:0000945 base pairing with snRNA Added DEFINITION Interacting selectively with small nuclear ribonucleic acid (snRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target snRNA molecule.
2008-03-11 GO:0000946 base pairing with tRNA Added DEFINITION Interacting selectively with transfer ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target tRNA molecule.
2008-03-11 GO:0010540 basipetal auxin transport Added DEFINITION The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.
2008-03-11 GO:0033396 beta-alanine biosynthetic process via 3-ureidopropionate Updated DEFINITION The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.
2008-03-11 GO:0002815 biosynthetic process of antibacterial peptides active against Gram-positive bacteria Updated DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.
2008-03-11 GO:0004084 branched-chain-amino-acid transaminase activity Updated DEFINITION Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid. Includes catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate and anaologous reactions involving L-isoleucine and L-valine.
2008-03-11 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity Updated DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.
2008-03-11 GO:0060219 camera-type eye photoreceptor cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
2008-03-11 GO:0060220 camera-type eye photoreceptor cell fate commitment Added DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye.
2008-03-11 GO:0033231 carbohydrate export Updated DEFINITION The directed movement of carbohydrates out of a cell or organelle.
2008-03-11 GO:0002306 CD4-positive gamma-delta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0002301 CD4-positive, alpha-beta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2008-03-11 GO:0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
2008-03-11 GO:0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0002307 CD8-positive, alpha-beta regulatory T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.
2008-03-11 GO:0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0007050 cell cycle arrest Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M).
2008-03-11 GO:0030996 cell cycle arrest in response to nitrogen starvation Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen.
2008-03-11 GO:0000751 cell cycle arrest in response to pheromone Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a pheromone stimulus.
2008-03-11 GO:0021883 cell cycle arrest of committed forebrain neuronal progenitor cell Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain.
2008-03-11 GO:0043165 Gram-negative-bacterium-type cell outer membrane assembly Updated DEFINITION The assembly of an outer membrane, a lipid bilayer that forms the outermost layer of the cell envelope typical of Gram-negative bacteria, which is enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
2008-03-11 GO:0044260 cellular macromolecule metabolic process Updated DEFINITION The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
2008-03-11 GO:0022824 transmitter-gated ion channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0032196 transposition Updated DEFINITION Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0008240 tripeptidyl-peptidase activity Added DEFINITION Catalysis of the release of an N-terminal tripeptide from a polypeptide.
2008-03-11 GO:0004294 tripeptidyl-peptidase II activity Updated DEFINITION Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH.
2008-03-11 GO:0034227 tRNA thio-modification Added DEFINITION The addition a sulfur atom to a nucleotide in a tRNA molecule.
2008-03-11 GO:0030738 tyramine N-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = S-adenosyl-L-homocysteine + N-methyltyramine.
2008-03-11 GO:0005941 unlocalized protein complex Updated DEFINITION OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products.
2008-03-11 GO:0032327 W-molybdopterin cofactor catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
2008-03-11 GO:0033871 [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.
2008-03-11 GO:0005606 laminin-1 complex Updated DEFINITION A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0043259 laminin-10 complex Updated DEFINITION A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0043260 laminin-11 complex Updated DEFINITION A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0043261 laminin-12 complex Updated DEFINITION A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.
2008-03-11 GO:0005607 laminin-2 complex Updated DEFINITION A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0005608 laminin-3 complex Updated DEFINITION A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0005609 laminin-4 complex Updated DEFINITION A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0005610 laminin-5 complex Updated DEFINITION A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.
2008-03-11 GO:0005611 laminin-6 complex Updated DEFINITION A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0005612 laminin-7 complex Updated DEFINITION A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0043257 laminin-8 complex Updated DEFINITION A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0043258 laminin-9 complex Updated DEFINITION A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0033996 levan fructotransferase (DFA-IV-forming) activity Updated DEFINITION Catalysis of the reaction: Produces di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
2008-03-11 GO:0010493 Lewis a epitope biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-1->4(Gal-beta-1->3)GlcNAc) characteristic of plant protein N-linked oligosaccharides.
2008-03-11 GO:0030751 licodione 2'-O-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + licodione = S-adenosyl-L-homocysteine + 2'-O-methyllicodione.
2008-03-11 GO:0060229 lipase activator activity Added DEFINITION Increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.
2008-03-11 GO:0060230 lipoprotein lipase activator activity Added DEFINITION Increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.
2008-03-11 GO:0015361 low affinity sodium:dicarboxylate symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
2008-03-11 GO:0005362 low-affinity glucose:sodium symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
2008-03-11 GO:0008647 low-affinity hexose transport Added DEFINITION The directed, low-affinity movement of a hexose into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
2008-03-11 GO:0034256 chlorophyll(ide) b reductase activity Added DEFINITION Catalysis of the reaction: 71-hydroxychlorophyllide a + NAD(P)+ = chlorophyllide b + NAD(P)H + H+.
2008-03-11 GO:0010277 chlorophyllide a oxygenase [overall] activity Updated DEFINITION Catalysis of hydroxylation at the 7-methyl group of chlorophyllide a, according to the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+ and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.
2008-03-11 GO:0009573 chloroplast ribulose bisphosphate carboxylase complex Updated DEFINITION A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
2008-03-11 GO:0033999 chondroitin B lyase activity Updated DEFINITION Catalysis of the reaction: Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S).
2008-03-11 GO:0048494 chromatophore ribulose bisphosphate carboxylase complex Updated DEFINITION A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
2008-03-11 GO:0043780 cobalt-precorrin-5B C1-methyltransferase activity Updated DEFINITION Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A.
2008-03-11 GO:0030938 collagen type XVIII trimer Updated DEFINITION A collagen homotrimer of alpha1(XVIII) chains.
2008-03-11 GO:0021540 corpus callosum morphogenesis Updated DEFINITION The process by which the anatomical structures of the corpus callosum are generated and organized. Morphogenesis pertains to the creation of form. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.
2008-03-11 GO:0008420 CTD phosphatase activity Updated DEFINITION Catalysis of the reaction: phospho-(DNA-directed RNA polymerase) + H2O = (DNA-directed RNA polymerase) + phosphate.
2008-03-11 GO:0034270 CVT complex Added DEFINITION A receptor-cargo protein complex that is involved in the CVT pathway. In budding yeast, the CVT complex consists of the preApe1p and Atg19p proteins.
2008-03-11 GO:0047821 D-glutamate oxidase activity Updated DEFINITION Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2; D-aspartate + H2O = oxaloacetate + NH3 + H2O2.
2008-03-11 GO:0060216 definitive hemopoiesis Added DEFINITION A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
2008-03-11 GO:0034268 discadenine biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
2008-03-11 GO:0034269 discadenine catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
2008-03-11 GO:0034267 discadenine metabolic process Added DEFINITION The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
2008-03-11 GO:0042575 DNA polymerase complex Updated DEFINITION A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.
2008-03-11 GO:0003916 DNA topoisomerase activity Updated DEFINITION Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
2008-03-11 GO:0000837 Doa10p ubiquitin ligase complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates membranes proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.
2008-03-11 GO:0060214 endocardium formation Added DEFINITION Formation of the inner endothelial cell layer of the heart, which connects the heart to the vascular system.
2008-03-11 GO:0034230 enkephalin processing Added DEFINITION The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.
2008-03-11 GO:0000835 ER ubiquitin ligase complex Added DEFINITION A ubiquitin ligase complex found in the ER.
2008-03-11 GO:0034056 estrogen response element binding Updated DEFINITION Interacting selectively with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.
2008-03-11 GO:0034228 ethanolamine transmembrane transporter activity Added DEFINITION Catalysis of the transfer of ethanolamine from one side of the membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
2008-03-11 GO:0034229 ethanolamine transport Added DEFINITION The directed movement of ethanolamine into, out of, within or between cells. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
2008-03-11 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity Added DEFINITION Catalysis of the phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (EIF2).
2008-03-11 GO:0008068 extracellular-glutamate-gated chloride channel activity Updated DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0005234 extracellular-glutamate-gated ion channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0016934 extracellular-glycine-gated chloride channel activity Updated DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0016933 extracellular-glycine-gated ion channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0001310 extrachromosomal rDNA circle accumulation involved in replicative cell aging Updated DEFINITION Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
2008-03-11 GO:0033078 extrathymic T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.
2008-03-11 GO:0009272 fungal-type cell wall biogenesis Updated DEFINITION The chemical reactions and pathways resulting in the formation of the fungal-type cell wall.
2008-03-11 GO:0031505 fungal-type cell wall organization Updated DEFINITION A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
2008-03-11 GO:0034221 fungal-type cell wall chitin biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of vegetatively growing fungal cells.
2008-03-11 GO:0051278 fungal-type cell wall polysaccharide biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.
2008-03-11 GO:0005760 gamma DNA polymerase complex Updated DEFINITION A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA.
2008-03-11 GO:0002304 gamma-delta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity Updated DEFINITION Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.
2008-03-11 GO:0048142 germarium-derived cystoblast division Updated DEFINITION The four rounds of incomplete mitosis undergone by a cystoblast derived from the germarium to form a 16-cell cyst. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells.
2008-03-11 GO:0030708 germarium-derived female germ-line cyst encapsulation Updated DEFINITION Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium.
2008-03-11 GO:0030727 germarium-derived female germ-line cyst formation Updated DEFINITION Formation of a cluster of germ-line cells, in the germarium, derived from a single founder cell (cystoblast).
2008-03-11 GO:0030706 germarium-derived oocyte differentiation Updated DEFINITION The process whereby one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte.
2008-03-11 GO:0007294 germarium-derived oocyte fate determination Updated DEFINITION Process by which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.
2008-03-11 GO:0021780 glial cell fate specification Updated DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
2008-03-11 GO:0009117 nucleotide metabolic process Updated DEFINITION The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
2008-03-11 GO:0033945 oligoxyloglucan reducing-end-specific cellobiohydrolase activity Updated DEFINITION Catalysis of the reaction: hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-1,4-linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.
2008-03-11 GO:0045194 oxidized low-density lipoprotein catabolic process Updated DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the breakdown of oxidized low-density lipoproteins.
2008-03-11 GO:0007567 parturition Updated DEFINITION The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.
2008-03-11 GO:0019323 pentose catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
2008-03-11 GO:0015835 peptidoglycan transport Updated DEFINITION The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of, within or between cells.
2008-03-11 GO:0046189 phenol-containing compound biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers.
2008-03-11 GO:0019336 phenol-containing compound catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
2008-03-11 GO:0018958 phenol-containing compound metabolic process Updated DEFINITION The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers.
2008-03-11 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity Added DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2008-03-11 GO:0000040 low-affinity iron ion transmembrane transport Added DEFINITION The directed, low-affinity movement of iron (Fe) ions into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
2008-03-11 GO:0006831 low-affinity zinc ion transport Added DEFINITION The directed, low-affinity movement of zinc (Zn) ions into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
2008-03-11 GO:0045192 low-density lipoprotein catabolic process Updated DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the breakdown of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats.
2008-03-11 GO:0032802 low-density lipoprotein particle receptor catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2008-03-11 GO:0002320 lymphoid progenitor cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.
2008-03-11 GO:0034226 lysine import Added DEFINITION The directed movement of lysine, 2,6-diaminohexanoic acid, into a cell or organelle.
2008-03-11 GO:0009059 macromolecule biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
2008-03-11 GO:0009057 macromolecule catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
2008-03-11 GO:0043170 macromolecule metabolic process Updated DEFINITION The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
2008-03-11 GO:0034238 macrophage fusion Added DEFINITION The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
2008-03-11 GO:0016058 maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling Updated DEFINITION Maintenance of the excited state of a photoreceptor cell to produce a steady state current as a result of signals generated by rhodopsin activation by a photon.
2008-03-11 GO:0030927 manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide Updated DEFINITION The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.
2008-03-11 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Updated DEFINITION Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
2008-03-11 GO:0034245 mitochondrial DNA-directed RNA polymerase complex Added DEFINITION A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.
2008-03-11 GO:0034246 mitochondrial RNA polymerase binding promoter specificity activity Added DEFINITION A transcription factor activity that confers promoter specificity upon mitochondrial RNA polymerase, in a manner analogous to eubacterial sigma factors.
2008-03-11 GO:0032326 Mo-molybdopterin cofactor catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2008-03-11 GO:0052158 modulation by symbiont of host resistance gene-dependent defense response Updated DEFINITION Any process by which an organism modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-03-11 GO:0002318 myeloid progenitor cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
2008-03-11 GO:0017018 myosin phosphatase activity Updated DEFINITION Catalysis of the reaction: phosphomysoin + H2O = myosin + phosphate.
2008-03-11 GO:0015764 N-acetylglucosamine transport Updated DEFINITION The directed movement of N-acetylglucosamine into, out of, within or between cells.
2008-03-11 GO:0003959 NADPH dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADPH + H+ + quinone acceptor = NADP+ + hydroquinone.
2008-03-11 GO:0002321 natural killer cell progenitor differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a natural killer cell progenitor.
2008-03-11 GO:0052130 negative aerotaxis Updated DEFINITION The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen.
2008-03-11 GO:0034252 negative regulation of cellular amide catabolic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
2008-03-11 GO:0034249 negative regulation of cellular amide metabolic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.
2008-03-11 GO:0010523 negative regulation of calcium ion transport into cytosol Added DEFINITION Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
2008-03-11 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate, or extent of CD4-positive, alpha beta T cell differentiation.
2008-03-11 GO:0045796 negative regulation of intestinal cholesterol absorption Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.
2008-03-11 GO:0034260 negative regulation of GTPase activity Added DEFINITION Any process that stops or reduces the rate of GTP hydrolysis by an GTPase.
2008-03-11 GO:0034240 negative regulation of macrophage fusion Added DEFINITION Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.
2008-03-11 GO:0003080 negative regulation of natriuresis Added DEFINITION Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.
2008-03-11 GO:0043322 negative regulation of natural killer cell degranulation Updated DEFINITION Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.
2008-03-11 GO:0051534 negative regulation of NFAT protein import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2008-03-11 GO:0000838 Hrd1p ubiquitin ligase ERAD-M complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
2008-03-11 GO:0010539 Hsp27 protein inhibitor activity Added DEFINITION Stops, prevents or reduces the activity of the Hsp27 molecular chaperone.
2008-03-11 GO:0010538 Hsp27 protein regulator activity Added DEFINITION Modulates the activity of the Hsp27 molecular chaperone.
2008-03-11 GO:0010546 Hsp90 protein inhibitor activity Added DEFINITION Stops, prevents or reduces the activity of the Hsp90 molecular chaperone.
2008-03-11 GO:0010545 Hsp90 protein regulator activity Added DEFINITION Binds to and modulates the activity of the molecular chaperone Hsp90.
2008-03-11 GO:0002327 immature B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an immature B cell.
2008-03-11 GO:0030747 indolepyruvate C-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.
2008-03-11 GO:0052290 induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction Updated DEFINITION The activation by an organism of the thickening of cell walls that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
2008-03-11 GO:0052105 induction by symbiont of defense-related host cell wall thickening Updated DEFINITION The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-03-11 GO:0002772 inhibitory C-type lectin receptor signaling pathway Updated DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.
2008-03-11 GO:0032003 interleukin-28 receptor binding Updated DEFINITION Interacting selectively with the interleukin-28 receptor.
2008-03-11 GO:0033997 inulin fructotransferase (DFA-I-forming) activity Updated DEFINITION Catalysis of the reaction: Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
2008-03-11 GO:0033998 inulin fructotransferase (DFA-III-forming) activity Updated DEFINITION Catalysis of the reaction: Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
2008-03-11 GO:0034231 islet amyloid polypeptide processing Added DEFINITION The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).
2008-03-11 GO:0034265 isopentenyl adenine biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.
2008-03-11 GO:0034266 isopentenyl adenine catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.
2008-03-11 GO:0034264 isopentenyl adenine metabolic process Added DEFINITION The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine.
2008-03-11 GO:0008579 JUN kinase phosphatase activity Updated DEFINITION Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.
2008-03-11 GO:0033918 kappa-carrageenase activity Updated DEFINITION Catalysis of the reaction: endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.
2008-03-11 GO:0034276 kynurenic acid biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
2008-03-11 GO:0034275 kynurenic acid metabolic process Added DEFINITION The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
2008-03-11 GO:0034298 arthrospore formation Added SYNONYM arthroconidium formation
2008-03-11 GO:0034299 reproductive blastospore formation Added SYNONYM blastoconidium formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added SYNONYM regulation of asexual spore formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added SYNONYM regulation of mitotic spore formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added SYNONYM regulation of mitotic sporulation
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM MAPKKK cascade during sporulation (sensu Fungi)
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM regulation of meiotic spore formation
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM regulation of meiotic sporulation
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM regulation of sexual spore formation
2008-03-11 GO:0052218 positive energy taxis in environment of other organism involved in symbiotic interaction Updated DEFINITION The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
2008-03-11 GO:0052118 positive energy taxis in host environment Updated DEFINITION The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-03-11 GO:0010536 positive regulation of activation of Janus kinase activity Added DEFINITION Any process that increases the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-03-11 GO:0010537 positive regulation of activation of JAK1 kinase activity Added DEFINITION Any process that increases the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-03-11 GO:0010535 positive regulation of activation of JAK2 kinase activity Added DEFINITION Any process that increase the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
2008-03-11 GO:0034253 positive regulation of cellular amide catabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
2008-03-11 GO:0034250 positive regulation of cellular amide metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.
2008-03-11 GO:0010524 positive regulation of calcium ion transport into cytosol Added DEFINITION Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
2008-03-11 GO:0007228 positive regulation of hh target transcription factor activity Updated DEFINITION Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.
2008-03-11 GO:0034241 positive regulation of macrophage fusion Added DEFINITION Any process that activates or increases the frequency, rate or extent of macrophage fusion.
2008-03-11 GO:0051142 positive regulation of NK T cell proliferation Updated DEFINITION Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.
2008-03-11 GO:0060225 positive regulation of retinal rod cell fate commitment Added DEFINITION Any process that increases the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter Added DEFINITION Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter.
2008-03-11 GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter Updated DEFINITION Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2008-03-11 GO:0007072 positive regulation of transcription on exit from mitosis Updated DEFINITION Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0007073 positive regulation of transcription on exit from mitosis, from RNA polymerase I promoter Added DEFINITION Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0007074 positive regulation of transcription on exit from mitosis, from RNA polymerase II promoter Added DEFINITION Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0007075 positive regulation of transcription on exit from mitosis, from RNA polymerase III promoter Added DEFINITION Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0045903 positive regulation of translational fidelity Updated DEFINITION Any process that increases the ability of the translational apparatus to interpret the genetic code.
2008-03-11 GO:0010530 positive regulation of transposition Added DEFINITION Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0010527 positive regulation of transposition, RNA-mediated Added DEFINITION Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
2008-03-11 GO:0002329 pre-B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
2008-03-11 GO:0004727 prenylated protein tyrosine phosphatase activity Updated DEFINITION Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate.
2008-03-11 GO:0060215 primitive hemopoiesis Added DEFINITION A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
2008-03-11 GO:0002328 pro-B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
2008-03-11 GO:0002572 pro-T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
2008-03-11 GO:0032947 protein complex scaffold Updated DEFINITION Functions to provide a physical suport for the assembly of a multiprotein complex.
2008-03-11 GO:0034214 protein hexamerization Added DEFINITION The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
2008-03-11 GO:0051018 protein kinase A binding Updated DEFINITION Interacting selectively with any subunit of protein kinase A.
2008-03-11 GO:0034236 protein kinase A catalytic subunit binding Added DEFINITION Interacting selectively with one or both of the catalytic subunits of protein kinase A.
2008-03-11 GO:0034237 protein kinase A regulatory subunit binding Added DEFINITION Interacting selectively with one or both of the regulatory subunits of protein kinase A.
2008-03-11 GO:0008330 protein tyrosine/threonine phosphatase activity Added DEFINITION Catalysis of the reaction: protein threonine/tyrosine phosphate + H2O = protein threonine/tyrosine + phosphate.
2008-03-11 GO:0001614 purinergic nucleotide receptor activity Added DEFINITION Combining with a purine nucleotide to initiate a change in cell activity.
2008-03-11 GO:0034271 phosphatidylinositol 3-kinase complex I Added DEFINITION A protein complex that posseses phosphatidylinositol 3-kinase activity and is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Atg14p and Vps15p.
2008-03-11 GO:0034272 phosphatidylinositol 3-kinase complex II Added DEFINITION A protein complex that posseses phosphatidylinositol 3-kinase activity and is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, VPS38 and Vps15p.
2008-03-11 GO:0051696 pointed-end actin filament uncapping Updated DEFINITION The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
2008-03-11 GO:0052131 positive aerotaxis Updated DEFINITION The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.
2008-03-11 GO:0010544 negative regulation of platelet activation Added DEFINITION Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
2008-03-11 GO:0034261 negative regulation of Ras GTPase activity Added DEFINITION Any process that stops or reduces the rate of activity of a GTPase of the Ras superfamily.
2008-03-11 GO:0060226 negative regulation of retinal cone cell fate commitment Added DEFINITION Any process that increases the process whereby a cell becomes commited to a retinal cone cell fate. Retinal cone cell fate commitment is the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
2008-03-11 GO:0034259 negative regulation of Rho GTPase activity Added DEFINITION Any process that stops or reduces the rate of activity of a GTPase of the Rho family.
2008-03-11 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides, catalyzed by RNA polymerase II.
2008-03-11 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter Added DEFINITION Any process that decreases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter.
2008-03-11 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion Added DEFINITION Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
2008-03-11 GO:0000437 carbon catabolite repression of transcription from RNA polymerase II promoter Updated DEFINITION Any process involving carbon catabolites that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2008-03-11 GO:0045902 negative regulation of translational fidelity Updated DEFINITION Any process that decreases the ability of the translational apparatus to interpret the genetic code.
2008-03-11 GO:0010529 negative regulation of transposition Added DEFINITION Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0010526 negative regulation of transposition, RNA-mediated Added DEFINITION Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
2008-03-11 GO:0010554 neurotransmitter secretory pathway Added DEFINITION A regulated secretory pathway in which neurotransmitters are initially stored in secretory vesicles for later release.
2008-03-11 GO:0034258 nicotinamide riboside transport Added DEFINITION The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of, within or between cells.
2008-03-11 GO:0034257 nicotinamide riboside transmembrane transporter activity Added DEFINITION Catalysis of the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.
2008-03-11 GO:0001865 NK T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a NK T cell.
2008-03-11 GO:0060227 Notch signaling pathway involved in camera-type eye photoreceptor fate commitment Added DEFINITION The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.
2008-03-11 GO:0000389 mRNA 3'-splice site recognition Updated DEFINITION Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.
2008-03-11 GO:0033171 nucleoprotein filament-forming ATPase activity Updated DEFINITION OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament.
2008-03-11 GO:0046173 polyol biosynthetic process Added SYNONYM polyhydric alcohol biosynthetic process
2008-03-11 GO:0046174 polyol catabolic process Added SYNONYM polyhydric alcohol catabolic process
2008-03-11 GO:0030436 asexual sporulation Deleted SYNONYM spore formation (sensu Bacteria)
2008-03-11 GO:0030437 ascospore formation Deleted SYNONYM ascospore formation
2008-03-11 GO:0030437 ascospore formation Deleted SYNONYM spore formation (sensu Fungi)
2008-03-11 GO:0042764 ascospore-type prospore Deleted SYNONYM forespore (sensu Fungi)
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Deleted SYNONYM spore wall chitin breakdown
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Deleted SYNONYM spore wall chitin catabolism
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Deleted SYNONYM spore wall chitin degradation
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Deleted SYNONYM regulation of spore wall chitin breakdown
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Deleted SYNONYM regulation of spore wall chitin catabolism
2008-03-11 GO:0042173 regulation of sporulation resulting in formation of a cellular spore Deleted SYNONYM MAPKKK cascade during sporulation (sensu Fungi)
2008-03-11 GO:0042173 regulation of sporulation resulting in formation of a cellular spore Deleted SYNONYM MAPKKK cascade during sporulation (sensu Saccharomyces)
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin synthesis
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin anabolism
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin biosynthesis
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin formation
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin synthesis
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Deleted SYNONYM regulation of spore wall chitin degradation
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin anabolism
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin biosynthesis
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin formation
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Deleted SYNONYM spore wall chitin metabolism
2008-03-11 GO:0019751 polyol metabolic process Added SYNONYM polyhydric alcohol metabolic process
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM asexual spore formation
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM mitotic spore formation
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM mitotic sporulation
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM spore formation (sensu Bacteria)
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM sporulation (sensu Bacteria)
2008-03-11 GO:0030437 ascospore formation Added SYNONYM spore formation (sensu Fungi)
2008-03-11 GO:0030437 ascospore formation Added SYNONYM sporulation (sensu Fungi)
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin anabolism
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin biosynthesis
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin formation
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin synthesis
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Added SYNONYM ascospore wall chitin metabolism
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin anabolism
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin biosynthesis
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin formation
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin synthesis
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added SYNONYM ascospore wall chitin breakdown
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added SYNONYM ascospore wall chitin catabolism
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added SYNONYM ascospore wall chitin degradation
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added SYNONYM regulation of ascospore wall chitin breakdown
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added SYNONYM regulation of ascospore wall chitin catabolism
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added SYNONYM regulation of ascospore wall chitin degradation
2008-03-11 GO:0034293 sexual sporulation Added SYNONYM meiotic spore formation
2008-03-11 GO:0034293 sexual sporulation Added SYNONYM meiotic sporulation
2008-03-11 GO:0034293 sexual sporulation Added SYNONYM sexual spore formation
2008-03-11 GO:0034294 sexual spore wall assembly Added SYNONYM sexual spore wall formation
2008-03-11 GO:0034307 regulation of ascospore formation Added SYNONYM MAPKKK cascade during sporulation (sensu Saccharomyces)
2008-03-11 GO:0034308 primary alcohol metabolic process Added SYNONYM monohydric alcohol metabolism
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol anabolism
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol biosynthesis
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol formation
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol synthesis
2008-03-11 GO:0034310 primary alcohol catabolic process Added SYNONYM monohydric alcohol breakdown
2008-03-11 GO:0034310 primary alcohol catabolic process Added SYNONYM monohydric alcohol catabolism
2008-03-11 GO:0034310 primary alcohol catabolic process Added SYNONYM monohydric alcohol degradation
2008-03-11 GO:0034311 diol metabolic process Added SYNONYM dihydric alcohol metabolic process
2008-03-11 GO:0034311 diol metabolic process Added SYNONYM diol metabolism
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM dihydric alcohol biosynthetic process
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol anabolism
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol biosynthesis
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol formation
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol synthesis
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM dihydric alcohol catabolic process
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM diol breakdown
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM diol catabolism
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM diol degradation
2008-03-11 GO:0042243 asexual spore wall assembly Added SYNONYM asexual spore wall formation
2008-03-11 GO:0042243 asexual spore wall assembly Added SYNONYM spore wall assembly (sensu Bacteria)
2008-03-11 GO:0042244 spore wall assembly Added SYNONYM spore wall formation
2008-03-11 GO:0042764 ascospore-type prospore Added SYNONYM forespore (sensu Fungi)

Terms

Timestamp GO ID GO Term Name Action Category Detail
2008-03-11 GO:0010567 regulation of ketone catabolic process Added TERM regulation of ketone catabolic process
2008-03-11 GO:0030436 asexual sporulation Updated TERM asexual sporulation
2008-03-11 GO:0030437 ascospore formation Updated TERM ascospore formation
2008-03-11 GO:0030476 ascospore wall assembly Updated TERM ascospore wall assembly
2008-03-11 GO:0010562 positive regulation of phosphorus metabolic process Added TERM positive regulation of phosphorus metabolic process
2008-03-11 GO:0010563 negative regulation of phosphorus metabolic process Added TERM negative regulation of phosphorus metabolic process
2008-03-11 GO:0010564 regulation of cell cycle process Added TERM regulation of cell cycle process
2008-03-11 GO:0010565 regulation of cellular ketone metabolic process Added TERM regulation of ketone metabolic process
2008-03-11 GO:0010566 regulation of ketone biosynthetic process Added TERM regulation of ketone biosynthetic process
2008-03-11 GO:0034294 sexual spore wall assembly Added TERM sexual spore wall assembly
2008-03-11 GO:0034295 basidiospore formation Added TERM basidiospore formation
2008-03-11 GO:0034296 zygospore formation Added TERM zygospore formation
2008-03-11 GO:0034297 oidium formation Added TERM oidium formation
2008-03-11 GO:0034298 arthrospore formation Added TERM arthrospore formation
2008-03-11 GO:0034299 reproductive blastospore formation Added TERM blastospore formation
2008-03-11 GO:0034300 sporangiospore formation Added TERM sporangiospore formation
2008-03-11 GO:0034301 endospore formation Added TERM endospore formation
2008-03-11 GO:0034302 akinete formation Added TERM akinete formation
2008-03-11 GO:0034303 myxospore formation Added TERM myxospore formation
2008-03-11 GO:0034304 actinomycete-type spore formation Added TERM actinomycete-type spore formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added TERM regulation of asexual sporulation
2008-03-11 GO:0034306 regulation of sexual sporulation Added TERM regulation of sexual sporulation
2008-03-11 GO:0034307 regulation of ascospore formation Added TERM regulation of ascospore formation
2008-03-11 GO:0034308 primary alcohol metabolic process Added TERM monohydric alcohol metabolic process
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added TERM monohydric alcohol biosynthetic process
2008-03-11 GO:0034310 primary alcohol catabolic process Added TERM monohydric alcohol catabolic process
2008-03-11 GO:0034311 diol metabolic process Added TERM diol metabolic process
2008-03-11 GO:0034312 diol biosynthetic process Added TERM diol biosynthetic process
2008-03-11 GO:0034313 diol catabolic process Added TERM diol catabolic process
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Updated TERM ascospore wall chitin biosynthetic process
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Updated TERM ascospore wall chitin metabolic process
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Updated TERM regulation of ascospore wall chitin biosynthetic process
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Updated TERM ascospore wall chitin catabolic process
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Updated TERM regulation of ascospore wall chitin catabolic process
2008-03-11 GO:0031321 ascospore-type prospore assembly Updated TERM ascospore-type prospore formation
2008-03-11 GO:0031322 ascospore-type prospore-specific spindle pole body remodeling Updated TERM ascospore-type prospore-specific spindle pole body modification
2008-03-11 GO:0032120 ascospore-type prospore membrane assembly Updated TERM ascospore-type prospore membrane formation
2008-03-11 GO:0042243 asexual spore wall assembly Updated TERM asexual spore wall assembly
2008-03-11 GO:0042763 intracellular immature spore Updated TERM intracellular immature spore
2008-03-11 GO:0042764 ascospore-type prospore Updated TERM ascospore-type prospore
2008-03-11 GO:0034293 sexual sporulation Added TERM sexual sporulation

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2008-03-11 GO:0034220 ion transmembrane transport Added DEFINITION The process whereby an ion is transported from one side of a membrane to the other.
2008-03-11 GO:0034274 Atg12-Atg5-Atg16 complex Added DEFINITION A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.
2008-03-11 GO:0034273 ATG1/UKL1 signaling complex Added DEFINITION A protein complex that contains a protein kinase and is required for the autophagosome formation. In budding yeast this complex consists of the kinase Atg1p, Atg13p and Atg17p.
2008-03-11 GO:0004931 extracellular ATP-gated cation channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0006914 autophagy Updated DEFINITION The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
2008-03-11 GO:0034262 autophagy in response to cellular starvation Added DEFINITION The process by which cells digest parts of their own cytoplasm in response to deprivation of nourishment.
2008-03-11 GO:0034263 autophagy in response to ER overload Added DEFINITION The process by which cells digest parts of their own cytoplasm in response to the accumulation of misfolded proteins in the endoplasmic reticulum.
2008-03-11 GO:0030183 B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a B cell.
2008-03-11 GO:0047514 1,3-beta-D-glucan phosphorylase activity Updated DEFINITION Catalysis of the reaction: 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.
2008-03-11 GO:0047515 1,3-beta-oligoglucan phosphorylase activity Updated DEFINITION Catalysis of the reaction: oligomeric 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.
2008-03-11 GO:0005943 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex Updated DEFINITION A heterodimeric protein complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic Class IA phosphoinositide 3-kinase (PI3K) subunit of 110-120 kDa and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.
2008-03-11 GO:0005944 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex Updated DEFINITION A heterodimeric protein complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic Class IB phosphoinositide 3-kinase (PI3K) subunit of 110-120 kDa and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.
2008-03-11 GO:0051166 2,5-dihydroxypyridine catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.
2008-03-11 GO:0047011 2-dehydropantolactone reductase (A-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-03-11 GO:0019141 2-dehydropantolactone reductase (B-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
2008-03-11 GO:0043724 2-keto-3-deoxygalactonate aldolase activity Updated DEFINITION Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate.
2008-03-11 GO:0018167 protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine Updated DEFINITION The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.
2008-03-11 GO:0034035 purine ribonucleoside bisphosphate metabolic process Updated DEFINITION The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a glycosamine consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on its glycose moiety.
2008-03-11 GO:0045028 G-protein coupled purinergic nucleotide receptor activity Added DEFINITION Combining with a purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2008-03-11 GO:0009198 pyrimidine deoxyribonucleoside diphosphate catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a glycosamine consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on its glycose moiety.
2008-03-11 GO:0034213 quinolinate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
2008-03-11 GO:0032482 Rab protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
2008-03-11 GO:0010533 regulation of activation of Janus kinase activity Added DEFINITION Any process that modulates the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-03-11 GO:0010532 regulation of activation of JAK1 kinase activity Added DEFINITION Any process that modulates the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-03-11 GO:0010534 regulation of activation of JAK2 kinase activity Added DEFINITION Any process that modulates the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
2008-03-11 GO:0034251 regulation of cellular amide catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
2008-03-11 GO:0034248 regulation of cellular amide metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.
2008-03-11 GO:0010522 regulation of calcium ion transport into cytosol Added DEFINITION Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
2008-03-11 GO:0034233 regulation of cell wall chitin catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.
2008-03-11 GO:0034222 regulation of cell wall chitin metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.
2008-03-11 GO:0003106 negative regulation of glomerular filtration by angiotensin Added DEFINITION The process by which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
2008-03-11 GO:0034239 regulation of macrophage fusion Added DEFINITION Any process that modulates the frequency, rate or extent of macrophage fusion.
2008-03-11 GO:0010549 regulation of membrane disassembly Added DEFINITION Any process that modulates the frequency, rate or extent of membrane disassembly.
2008-03-11 GO:0003078 regulation of natriuresis Added DEFINITION Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.
2008-03-11 GO:0010543 regulation of platelet activation Added DEFINITION Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
2008-03-11 GO:0010550 regulation of PSII associated light-harvesting complex II catabolic process Added DEFINITION Any process that modulates the catabolism of one or more components of the light-harvesting complex of photosystem II.
2008-03-11 GO:0060222 regulation of retinal cone cell fate commitment Added DEFINITION Any process that modulates the process whereby a cell becomes commited to a retinal cone cell fate. Retinal cone cell fate commitment is the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
2008-03-11 GO:0060224 regulation of retinal rod cell fate commitment Added DEFINITION Any process that modulates the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter Added DEFINITION Any process that modulates the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides, catalyzed by RNA polymerase II.
2008-03-11 GO:0014708 regulation of somitomeric trunk muscle development Updated DEFINITION Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.
2008-03-11 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter Added DEFINITION Any process that modulates the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter.
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of spore wall chitin.
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of spore wall chitin.
2008-03-11 GO:0060092 regulation of synaptic transmission, glycinergic Updated DEFINITION Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
2008-03-11 GO:0010548 regulation of thylakoid membrane disassembly Added DEFINITION Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.
2008-03-11 GO:0034225 regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation Added DEFINITION Modulation of the frequency, rate or extent of transcription from an from RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions.
2008-03-11 GO:0006450 regulation of translational fidelity Updated DEFINITION Any process that modulates the ability of the translational apparatus to interpret the genetic code.
2008-03-11 GO:0043561 regulation of translational initiation in response to osmotic stress Updated DEFINITION Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
2008-03-11 GO:0010528 regulation of transposition Added DEFINITION Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0010525 regulation of transposition, RNA-mediated Added DEFINITION Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
2008-03-11 GO:0034254 regulation of urea catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.
2008-03-11 GO:0034224 cellular response to zinc ion starvation Added DEFINITION A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.
2008-03-11 GO:0047026 androsterone dehydrogenase (A-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
2008-03-11 GO:0047042 androsterone dehydrogenase (B-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
2008-03-11 GO:0005945 6-phosphofructokinase complex Updated DEFINITION A protein complex that possesses 6-phosphofructokinase activity; homodimeric and allosteric homotetrameric forms are known.
2008-03-11 GO:0045193 acetylated low-density lipoprotein catabolic process Updated DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetylated low-density lipoproteins.
2008-03-11 GO:0010541 acropetal auxin transport Added DEFINITION The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.
2008-03-11 GO:0004284 acrosin activity Updated DEFINITION Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa.
2008-03-11 GO:0051488 activation of anaphase-promoting complex activity Updated DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex.
2008-03-11 GO:0051487 activation of anaphase-promoting complex activity involved in meiotic cell cycle Updated DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the meiotic cell cycle.
2008-03-11 GO:0007092 activation of mitotic anaphase-promoting complex activity Updated DEFINITION Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the mitotic cell cycle.
2008-03-11 GO:0010531 activation of JAK1 kinase activity Added DEFINITION The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-03-11 GO:0032861 activation of Rap GTPase activity Updated DEFINITION Any process that initiates the activity of an inactive GTPase of the Rap family through the replacement of GDP by GTP.
2008-03-11 GO:0003996 acyl-CoA ligase activity Added DEFINITION Catalysis of the reaction: an acyl + ATP + CoASH = AMP + diphosphate + acyl-CoA.
2008-03-11 GO:0001609 G-protein coupled adenosine receptor activity Added DEFINITION Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
2008-03-11 GO:0047380 ADP-dependent medium-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA.
2008-03-11 GO:0047379 ADP-dependent short-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA.
2008-03-11 GO:0002299 alpha-beta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0046632 alpha-beta T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an alpha-beta T cell.
2008-03-11 GO:0019561 anaerobic phenylalanine oxidation Added DEFINITION The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.
2008-03-11 GO:0048905 anterior lateral line neuromast mantle cell differentiation Updated DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2008-03-11 GO:0042895 antibiotic transporter activity Updated DEFINITION Enables the directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of, within or between cells.
2008-03-11 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway Updated DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2008-03-11 GO:0019546 arginine deiminase pathway Added DEFINITION The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.
2008-03-11 GO:0034255 regulation of urea metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.
2008-03-11 GO:0003117 regulation of vasoconstriction by circulating norepinephrine Updated DEFINITION Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.
2008-03-11 GO:0003125 regulation of vasodilation by circulating norepinephrine Updated DEFINITION Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.
2008-03-11 GO:0003126 regulation of vasodilation by neuronal norepinephrine Updated DEFINITION Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of norepinephrine released by nerve endings.
2008-03-11 GO:0010555 response to mannitol Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
2008-03-11 GO:0034201 response to oleic acid Updated DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a oleate stimulus.
2008-03-11 GO:0046551 retinal cone cell fate commitment Updated DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0060221 retinal rod cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a retinal rod cell.
2008-03-11 GO:0060223 retinal rod cell fate commitment Added DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0033890 ribonuclease D activity Updated DEFINITION Catalysis of the reaction: exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
2008-03-11 GO:0033587 shikimate biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.
2008-03-11 GO:0034247 snoRNA splicing Added DEFINITION The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.
2008-03-11 GO:0065001 specification of axis polarity Added DEFINITION The pattern specification process by which the polarity of a body or organ axis is established and maintained.
2008-03-11 GO:0007055 spindle assembly involved in male meiosis II Updated DEFINITION The formation of the spindle during meiosis II of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208).
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of spore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal-type spores.
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of spore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal-type spores.
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Added DEFINITION The chemical reactions and pathways involving spore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal-type spores.
2008-03-11 GO:0034209 sterol acetylation Updated DEFINITION The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
2008-03-11 GO:0034210 sterol deacetylation Updated DEFINITION The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
2008-03-11 GO:0050309 sugar-terminal-phosphatase activity Updated DEFINITION Catalysis of the reaction: H2O + a sugar phosphate = a sugar + phosphate; an example is D-glucose 6-phosphate + H2O = D-glucose + phosphate.
2008-03-11 GO:0030217 T cell differentiation Updated DEFINITION The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
2008-03-11 GO:0033077 T cell differentiation in thymus Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
2008-03-11 GO:0010521 telomerase inhibitor activity Added DEFINITION Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
2008-03-11 GO:0034215 thiamine:proton symporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamin(out) + H+(out) = thiamin(in) + H+(in).
2008-03-11 GO:0010547 thylakoid membrane disassembly Added DEFINITION The controlled breakdown of the thylakoid membrane in the context of a normal process.
2008-03-11 GO:0034219 carbohydrate transmembrane transport Added DEFINITION The process whereby a carbohydrate is transported from one side of a membrane to the other.
2008-03-11 GO:0046562 glucose oxidase activity Updated DEFINITION Catalysis of the reaction: a hexose + O2 = a hexno-1,5-lactone + H2O2; includes beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.
2008-03-11 GO:0015503 glutathione-regulated potassium exporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
2008-03-11 GO:0034235 GPI anchor binding Added DEFINITION Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
2008-03-11 GO:0048503 GPI anchor binding Updated DEFINITION OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
2008-03-11 GO:0051737 GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity Updated DEFINITION Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.
2008-03-11 GO:0060217 hemangioblast cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.
2008-03-11 GO:0002244 hematopoietic progenitor cell differentiation Updated DEFINITION The process whereby precursor cell type acquires the specialized features of a hemopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2008-03-11 GO:0060218 hematopoietic stem cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a hemopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
2008-03-11 GO:0015362 high affinity sodium:dicarboxylate symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0015678 high-affinity copper ion transport Added DEFINITION The directed, high-affinity movement of copper (Cu) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0015683 high-affinity ferric iron transport Added DEFINITION The directed, high-affinity movement of ferric (Fe(III) or Fe3+) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0008646 high-affinity hexose transport Added DEFINITION The directed, high-affinity movement of a hexose into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0005358 high-affinity hydrogen:glucose symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constituitive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0006827 high-affinity iron ion transmembrane transport Added DEFINITION The directed, high-affinity movement of iron (Fe) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0034216 high-affinity thiamine:proton symporter activity Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamin(out) + H+(out) = thiamin(in) + H+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0006830 high-affinity zinc ion transport Added DEFINITION The directed, high-affinity movement of zinc (Zn) ions into, out of, within or between cells. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-03-11 GO:0000836 Hrd1p ubiquitin ligase complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
2008-03-11 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
2008-03-11 GO:0000496 base pairing Added DEFINITION Interacting selectively with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target nucleic acid molecule.
2008-03-11 GO:0000497 base pairing with DNA Added DEFINITION Interacting selectively with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.
2008-03-11 GO:0000499 base pairing with mRNA Added DEFINITION Interacting selectively with messenger ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target mRNA molecule.
2008-03-11 GO:0000498 base pairing with RNA Added DEFINITION Interacting selectively with ribonucleic acid (RNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target RNA molecule.
2008-03-11 GO:0000944 base pairing with rRNA Added DEFINITION Interacting selectively with ribosomal ribonucleic acid (rRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target rRNA molecule.
2008-03-11 GO:0000945 base pairing with snRNA Added DEFINITION Interacting selectively with small nuclear ribonucleic acid (snRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target snRNA molecule.
2008-03-11 GO:0000946 base pairing with tRNA Added DEFINITION Interacting selectively with transfer ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target tRNA molecule.
2008-03-11 GO:0010540 basipetal auxin transport Added DEFINITION The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.
2008-03-11 GO:0033396 beta-alanine biosynthetic process via 3-ureidopropionate Updated DEFINITION The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.
2008-03-11 GO:0002815 biosynthetic process of antibacterial peptides active against Gram-positive bacteria Updated DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.
2008-03-11 GO:0004084 branched-chain-amino-acid transaminase activity Updated DEFINITION Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid. Includes catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate and anaologous reactions involving L-isoleucine and L-valine.
2008-03-11 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity Updated DEFINITION Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.
2008-03-11 GO:0060219 camera-type eye photoreceptor cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
2008-03-11 GO:0060220 camera-type eye photoreceptor cell fate commitment Added DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye.
2008-03-11 GO:0033231 carbohydrate export Updated DEFINITION The directed movement of carbohydrates out of a cell or organelle.
2008-03-11 GO:0002306 CD4-positive gamma-delta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0002301 CD4-positive, alpha-beta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2008-03-11 GO:0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
2008-03-11 GO:0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0002307 CD8-positive, alpha-beta regulatory T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.
2008-03-11 GO:0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0007050 cell cycle arrest Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M).
2008-03-11 GO:0030996 cell cycle arrest in response to nitrogen starvation Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen.
2008-03-11 GO:0000751 cell cycle arrest in response to pheromone Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a pheromone stimulus.
2008-03-11 GO:0021883 cell cycle arrest of committed forebrain neuronal progenitor cell Updated DEFINITION The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain.
2008-03-11 GO:0043165 Gram-negative-bacterium-type cell outer membrane assembly Updated DEFINITION The assembly of an outer membrane, a lipid bilayer that forms the outermost layer of the cell envelope typical of Gram-negative bacteria, which is enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
2008-03-11 GO:0044260 cellular macromolecule metabolic process Updated DEFINITION The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
2008-03-11 GO:0022824 transmitter-gated ion channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0032196 transposition Updated DEFINITION Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0008240 tripeptidyl-peptidase activity Added DEFINITION Catalysis of the release of an N-terminal tripeptide from a polypeptide.
2008-03-11 GO:0004294 tripeptidyl-peptidase II activity Updated DEFINITION Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH.
2008-03-11 GO:0034227 tRNA thio-modification Added DEFINITION The addition a sulfur atom to a nucleotide in a tRNA molecule.
2008-03-11 GO:0030738 tyramine N-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = S-adenosyl-L-homocysteine + N-methyltyramine.
2008-03-11 GO:0005941 unlocalized protein complex Updated DEFINITION OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products.
2008-03-11 GO:0032327 W-molybdopterin cofactor catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
2008-03-11 GO:0033871 [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.
2008-03-11 GO:0005606 laminin-1 complex Updated DEFINITION A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0043259 laminin-10 complex Updated DEFINITION A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0043260 laminin-11 complex Updated DEFINITION A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0043261 laminin-12 complex Updated DEFINITION A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.
2008-03-11 GO:0005607 laminin-2 complex Updated DEFINITION A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0005608 laminin-3 complex Updated DEFINITION A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0005609 laminin-4 complex Updated DEFINITION A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0005610 laminin-5 complex Updated DEFINITION A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.
2008-03-11 GO:0005611 laminin-6 complex Updated DEFINITION A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0005612 laminin-7 complex Updated DEFINITION A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0043257 laminin-8 complex Updated DEFINITION A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.
2008-03-11 GO:0043258 laminin-9 complex Updated DEFINITION A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains.
2008-03-11 GO:0033996 levan fructotransferase (DFA-IV-forming) activity Updated DEFINITION Catalysis of the reaction: Produces di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
2008-03-11 GO:0010493 Lewis a epitope biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-1->4(Gal-beta-1->3)GlcNAc) characteristic of plant protein N-linked oligosaccharides.
2008-03-11 GO:0030751 licodione 2'-O-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + licodione = S-adenosyl-L-homocysteine + 2'-O-methyllicodione.
2008-03-11 GO:0060229 lipase activator activity Added DEFINITION Increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.
2008-03-11 GO:0060230 lipoprotein lipase activator activity Added DEFINITION Increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.
2008-03-11 GO:0015361 low affinity sodium:dicarboxylate symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
2008-03-11 GO:0005362 low-affinity glucose:sodium symporter activity Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
2008-03-11 GO:0008647 low-affinity hexose transport Added DEFINITION The directed, low-affinity movement of a hexose into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
2008-03-11 GO:0034256 chlorophyll(ide) b reductase activity Added DEFINITION Catalysis of the reaction: 71-hydroxychlorophyllide a + NAD(P)+ = chlorophyllide b + NAD(P)H + H+.
2008-03-11 GO:0010277 chlorophyllide a oxygenase [overall] activity Updated DEFINITION Catalysis of hydroxylation at the 7-methyl group of chlorophyllide a, according to the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+ and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.
2008-03-11 GO:0009573 chloroplast ribulose bisphosphate carboxylase complex Updated DEFINITION A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
2008-03-11 GO:0033999 chondroitin B lyase activity Updated DEFINITION Catalysis of the reaction: Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S).
2008-03-11 GO:0048494 chromatophore ribulose bisphosphate carboxylase complex Updated DEFINITION A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
2008-03-11 GO:0043780 cobalt-precorrin-5B C1-methyltransferase activity Updated DEFINITION Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A.
2008-03-11 GO:0030938 collagen type XVIII trimer Updated DEFINITION A collagen homotrimer of alpha1(XVIII) chains.
2008-03-11 GO:0021540 corpus callosum morphogenesis Updated DEFINITION The process by which the anatomical structures of the corpus callosum are generated and organized. Morphogenesis pertains to the creation of form. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.
2008-03-11 GO:0008420 CTD phosphatase activity Updated DEFINITION Catalysis of the reaction: phospho-(DNA-directed RNA polymerase) + H2O = (DNA-directed RNA polymerase) + phosphate.
2008-03-11 GO:0034270 CVT complex Added DEFINITION A receptor-cargo protein complex that is involved in the CVT pathway. In budding yeast, the CVT complex consists of the preApe1p and Atg19p proteins.
2008-03-11 GO:0047821 D-glutamate oxidase activity Updated DEFINITION Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2; D-aspartate + H2O = oxaloacetate + NH3 + H2O2.
2008-03-11 GO:0060216 definitive hemopoiesis Added DEFINITION A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
2008-03-11 GO:0034268 discadenine biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
2008-03-11 GO:0034269 discadenine catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
2008-03-11 GO:0034267 discadenine metabolic process Added DEFINITION The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
2008-03-11 GO:0042575 DNA polymerase complex Updated DEFINITION A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.
2008-03-11 GO:0003916 DNA topoisomerase activity Updated DEFINITION Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
2008-03-11 GO:0000837 Doa10p ubiquitin ligase complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates membranes proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.
2008-03-11 GO:0060214 endocardium formation Added DEFINITION Formation of the inner endothelial cell layer of the heart, which connects the heart to the vascular system.
2008-03-11 GO:0034230 enkephalin processing Added DEFINITION The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.
2008-03-11 GO:0000835 ER ubiquitin ligase complex Added DEFINITION A ubiquitin ligase complex found in the ER.
2008-03-11 GO:0034056 estrogen response element binding Updated DEFINITION Interacting selectively with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.
2008-03-11 GO:0034228 ethanolamine transmembrane transporter activity Added DEFINITION Catalysis of the transfer of ethanolamine from one side of the membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
2008-03-11 GO:0034229 ethanolamine transport Added DEFINITION The directed movement of ethanolamine into, out of, within or between cells. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
2008-03-11 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity Added DEFINITION Catalysis of the phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (EIF2).
2008-03-11 GO:0008068 extracellular-glutamate-gated chloride channel activity Updated DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0005234 extracellular-glutamate-gated ion channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0016934 extracellular-glycine-gated chloride channel activity Updated DEFINITION Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0016933 extracellular-glycine-gated ion channel activity Updated DEFINITION Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
2008-03-11 GO:0001310 extrachromosomal rDNA circle accumulation involved in replicative cell aging Updated DEFINITION Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
2008-03-11 GO:0033078 extrathymic T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.
2008-03-11 GO:0009272 fungal-type cell wall biogenesis Updated DEFINITION The chemical reactions and pathways resulting in the formation of the fungal-type cell wall.
2008-03-11 GO:0031505 fungal-type cell wall organization Updated DEFINITION A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
2008-03-11 GO:0034221 fungal-type cell wall chitin biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of vegetatively growing fungal cells.
2008-03-11 GO:0051278 fungal-type cell wall polysaccharide biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.
2008-03-11 GO:0005760 gamma DNA polymerase complex Updated DEFINITION A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA.
2008-03-11 GO:0002304 gamma-delta intraepithelial T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2008-03-11 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity Updated DEFINITION Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.
2008-03-11 GO:0048142 germarium-derived cystoblast division Updated DEFINITION The four rounds of incomplete mitosis undergone by a cystoblast derived from the germarium to form a 16-cell cyst. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells.
2008-03-11 GO:0030708 germarium-derived female germ-line cyst encapsulation Updated DEFINITION Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium.
2008-03-11 GO:0030727 germarium-derived female germ-line cyst formation Updated DEFINITION Formation of a cluster of germ-line cells, in the germarium, derived from a single founder cell (cystoblast).
2008-03-11 GO:0030706 germarium-derived oocyte differentiation Updated DEFINITION The process whereby one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte.
2008-03-11 GO:0007294 germarium-derived oocyte fate determination Updated DEFINITION Process by which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.
2008-03-11 GO:0021780 glial cell fate specification Updated DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
2008-03-11 GO:0009117 nucleotide metabolic process Updated DEFINITION The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
2008-03-11 GO:0033945 oligoxyloglucan reducing-end-specific cellobiohydrolase activity Updated DEFINITION Catalysis of the reaction: hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-1,4-linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.
2008-03-11 GO:0045194 oxidized low-density lipoprotein catabolic process Updated DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the breakdown of oxidized low-density lipoproteins.
2008-03-11 GO:0007567 parturition Updated DEFINITION The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.
2008-03-11 GO:0019323 pentose catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
2008-03-11 GO:0015835 peptidoglycan transport Updated DEFINITION The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of, within or between cells.
2008-03-11 GO:0046189 phenol-containing compound biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers.
2008-03-11 GO:0019336 phenol-containing compound catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
2008-03-11 GO:0018958 phenol-containing compound metabolic process Updated DEFINITION The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. The largest single use of phenol is in the production of plastics, but it is also used in the synthesis of caprolactam, a precursor for nylon 6 and other man-made fibers.
2008-03-11 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity Added DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2008-03-11 GO:0000040 low-affinity iron ion transmembrane transport Added DEFINITION The directed, low-affinity movement of iron (Fe) ions into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
2008-03-11 GO:0006831 low-affinity zinc ion transport Added DEFINITION The directed, low-affinity movement of zinc (Zn) ions into, out of, within or between cells. In low affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
2008-03-11 GO:0045192 low-density lipoprotein catabolic process Updated DEFINITION OBSOLETE. The chemical reactions and pathways resulting in the breakdown of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats.
2008-03-11 GO:0032802 low-density lipoprotein particle receptor catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2008-03-11 GO:0002320 lymphoid progenitor cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.
2008-03-11 GO:0034226 lysine import Added DEFINITION The directed movement of lysine, 2,6-diaminohexanoic acid, into a cell or organelle.
2008-03-11 GO:0009059 macromolecule biosynthetic process Updated DEFINITION The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
2008-03-11 GO:0009057 macromolecule catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
2008-03-11 GO:0043170 macromolecule metabolic process Updated DEFINITION The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
2008-03-11 GO:0034238 macrophage fusion Added DEFINITION The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
2008-03-11 GO:0016058 maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling Updated DEFINITION Maintenance of the excited state of a photoreceptor cell to produce a steady state current as a result of signals generated by rhodopsin activation by a photon.
2008-03-11 GO:0030927 manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide Updated DEFINITION The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.
2008-03-11 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Updated DEFINITION Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
2008-03-11 GO:0034245 mitochondrial DNA-directed RNA polymerase complex Added DEFINITION A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.
2008-03-11 GO:0034246 mitochondrial RNA polymerase binding promoter specificity activity Added DEFINITION A transcription factor activity that confers promoter specificity upon mitochondrial RNA polymerase, in a manner analogous to eubacterial sigma factors.
2008-03-11 GO:0032326 Mo-molybdopterin cofactor catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
2008-03-11 GO:0052158 modulation by symbiont of host resistance gene-dependent defense response Updated DEFINITION Any process by which an organism modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-03-11 GO:0002318 myeloid progenitor cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
2008-03-11 GO:0017018 myosin phosphatase activity Updated DEFINITION Catalysis of the reaction: phosphomysoin + H2O = myosin + phosphate.
2008-03-11 GO:0015764 N-acetylglucosamine transport Updated DEFINITION The directed movement of N-acetylglucosamine into, out of, within or between cells.
2008-03-11 GO:0003959 NADPH dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADPH + H+ + quinone acceptor = NADP+ + hydroquinone.
2008-03-11 GO:0002321 natural killer cell progenitor differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a natural killer cell progenitor.
2008-03-11 GO:0052130 negative aerotaxis Updated DEFINITION The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen.
2008-03-11 GO:0034252 negative regulation of cellular amide catabolic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
2008-03-11 GO:0034249 negative regulation of cellular amide metabolic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.
2008-03-11 GO:0010523 negative regulation of calcium ion transport into cytosol Added DEFINITION Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
2008-03-11 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate, or extent of CD4-positive, alpha beta T cell differentiation.
2008-03-11 GO:0045796 negative regulation of intestinal cholesterol absorption Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.
2008-03-11 GO:0034260 negative regulation of GTPase activity Added DEFINITION Any process that stops or reduces the rate of GTP hydrolysis by an GTPase.
2008-03-11 GO:0034240 negative regulation of macrophage fusion Added DEFINITION Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.
2008-03-11 GO:0003080 negative regulation of natriuresis Added DEFINITION Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.
2008-03-11 GO:0043322 negative regulation of natural killer cell degranulation Updated DEFINITION Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.
2008-03-11 GO:0051534 negative regulation of NFAT protein import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2008-03-11 GO:0000838 Hrd1p ubiquitin ligase ERAD-M complex Added DEFINITION A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
2008-03-11 GO:0010539 Hsp27 protein inhibitor activity Added DEFINITION Stops, prevents or reduces the activity of the Hsp27 molecular chaperone.
2008-03-11 GO:0010538 Hsp27 protein regulator activity Added DEFINITION Modulates the activity of the Hsp27 molecular chaperone.
2008-03-11 GO:0010546 Hsp90 protein inhibitor activity Added DEFINITION Stops, prevents or reduces the activity of the Hsp90 molecular chaperone.
2008-03-11 GO:0010545 Hsp90 protein regulator activity Added DEFINITION Binds to and modulates the activity of the molecular chaperone Hsp90.
2008-03-11 GO:0002327 immature B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of an immature B cell.
2008-03-11 GO:0030747 indolepyruvate C-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.
2008-03-11 GO:0052290 induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction Updated DEFINITION The activation by an organism of the thickening of cell walls that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
2008-03-11 GO:0052105 induction by symbiont of defense-related host cell wall thickening Updated DEFINITION The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-03-11 GO:0002772 inhibitory C-type lectin receptor signaling pathway Updated DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.
2008-03-11 GO:0032003 interleukin-28 receptor binding Updated DEFINITION Interacting selectively with the interleukin-28 receptor.
2008-03-11 GO:0033997 inulin fructotransferase (DFA-I-forming) activity Updated DEFINITION Catalysis of the reaction: Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
2008-03-11 GO:0033998 inulin fructotransferase (DFA-III-forming) activity Updated DEFINITION Catalysis of the reaction: Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
2008-03-11 GO:0034231 islet amyloid polypeptide processing Added DEFINITION The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).
2008-03-11 GO:0034265 isopentenyl adenine biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.
2008-03-11 GO:0034266 isopentenyl adenine catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.
2008-03-11 GO:0034264 isopentenyl adenine metabolic process Added DEFINITION The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine.
2008-03-11 GO:0008579 JUN kinase phosphatase activity Updated DEFINITION Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.
2008-03-11 GO:0033918 kappa-carrageenase activity Updated DEFINITION Catalysis of the reaction: endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.
2008-03-11 GO:0034276 kynurenic acid biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
2008-03-11 GO:0034275 kynurenic acid metabolic process Added DEFINITION The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
2008-03-11 GO:0034298 arthrospore formation Added SYNONYM arthroconidium formation
2008-03-11 GO:0034299 reproductive blastospore formation Added SYNONYM blastoconidium formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added SYNONYM regulation of asexual spore formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added SYNONYM regulation of mitotic spore formation
2008-03-11 GO:0034305 regulation of asexual sporulation Added SYNONYM regulation of mitotic sporulation
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM MAPKKK cascade during sporulation (sensu Fungi)
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM regulation of meiotic spore formation
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM regulation of meiotic sporulation
2008-03-11 GO:0034306 regulation of sexual sporulation Added SYNONYM regulation of sexual spore formation
2008-03-11 GO:0052218 positive energy taxis in environment of other organism involved in symbiotic interaction Updated DEFINITION The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
2008-03-11 GO:0052118 positive energy taxis in host environment Updated DEFINITION The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-03-11 GO:0010536 positive regulation of activation of Janus kinase activity Added DEFINITION Any process that increases the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
2008-03-11 GO:0010537 positive regulation of activation of JAK1 kinase activity Added DEFINITION Any process that increases the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
2008-03-11 GO:0010535 positive regulation of activation of JAK2 kinase activity Added DEFINITION Any process that increase the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
2008-03-11 GO:0034253 positive regulation of cellular amide catabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
2008-03-11 GO:0034250 positive regulation of cellular amide metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.
2008-03-11 GO:0010524 positive regulation of calcium ion transport into cytosol Added DEFINITION Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
2008-03-11 GO:0007228 positive regulation of hh target transcription factor activity Updated DEFINITION Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.
2008-03-11 GO:0034241 positive regulation of macrophage fusion Added DEFINITION Any process that activates or increases the frequency, rate or extent of macrophage fusion.
2008-03-11 GO:0051142 positive regulation of NK T cell proliferation Updated DEFINITION Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.
2008-03-11 GO:0060225 positive regulation of retinal rod cell fate commitment Added DEFINITION Any process that increases the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
2008-03-11 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter Added DEFINITION Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter.
2008-03-11 GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter Updated DEFINITION Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2008-03-11 GO:0007072 positive regulation of transcription on exit from mitosis Updated DEFINITION Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0007073 positive regulation of transcription on exit from mitosis, from RNA polymerase I promoter Added DEFINITION Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0007074 positive regulation of transcription on exit from mitosis, from RNA polymerase II promoter Added DEFINITION Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0007075 positive regulation of transcription on exit from mitosis, from RNA polymerase III promoter Added DEFINITION Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2008-03-11 GO:0045903 positive regulation of translational fidelity Updated DEFINITION Any process that increases the ability of the translational apparatus to interpret the genetic code.
2008-03-11 GO:0010530 positive regulation of transposition Added DEFINITION Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0010527 positive regulation of transposition, RNA-mediated Added DEFINITION Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
2008-03-11 GO:0002329 pre-B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
2008-03-11 GO:0004727 prenylated protein tyrosine phosphatase activity Updated DEFINITION Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate.
2008-03-11 GO:0060215 primitive hemopoiesis Added DEFINITION A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
2008-03-11 GO:0002328 pro-B cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
2008-03-11 GO:0002572 pro-T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
2008-03-11 GO:0032947 protein complex scaffold Updated DEFINITION Functions to provide a physical suport for the assembly of a multiprotein complex.
2008-03-11 GO:0034214 protein hexamerization Added DEFINITION The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
2008-03-11 GO:0051018 protein kinase A binding Updated DEFINITION Interacting selectively with any subunit of protein kinase A.
2008-03-11 GO:0034236 protein kinase A catalytic subunit binding Added DEFINITION Interacting selectively with one or both of the catalytic subunits of protein kinase A.
2008-03-11 GO:0034237 protein kinase A regulatory subunit binding Added DEFINITION Interacting selectively with one or both of the regulatory subunits of protein kinase A.
2008-03-11 GO:0008330 protein tyrosine/threonine phosphatase activity Added DEFINITION Catalysis of the reaction: protein threonine/tyrosine phosphate + H2O = protein threonine/tyrosine + phosphate.
2008-03-11 GO:0001614 purinergic nucleotide receptor activity Added DEFINITION Combining with a purine nucleotide to initiate a change in cell activity.
2008-03-11 GO:0034271 phosphatidylinositol 3-kinase complex I Added DEFINITION A protein complex that posseses phosphatidylinositol 3-kinase activity and is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Atg14p and Vps15p.
2008-03-11 GO:0034272 phosphatidylinositol 3-kinase complex II Added DEFINITION A protein complex that posseses phosphatidylinositol 3-kinase activity and is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, VPS38 and Vps15p.
2008-03-11 GO:0051696 pointed-end actin filament uncapping Updated DEFINITION The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
2008-03-11 GO:0052131 positive aerotaxis Updated DEFINITION The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.
2008-03-11 GO:0010544 negative regulation of platelet activation Added DEFINITION Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
2008-03-11 GO:0034261 negative regulation of Ras GTPase activity Added DEFINITION Any process that stops or reduces the rate of activity of a GTPase of the Ras superfamily.
2008-03-11 GO:0060226 negative regulation of retinal cone cell fate commitment Added DEFINITION Any process that increases the process whereby a cell becomes commited to a retinal cone cell fate. Retinal cone cell fate commitment is the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
2008-03-11 GO:0034259 negative regulation of Rho GTPase activity Added DEFINITION Any process that stops or reduces the rate of activity of a GTPase of the Rho family.
2008-03-11 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides, catalyzed by RNA polymerase II.
2008-03-11 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter Added DEFINITION Any process that decreases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter.
2008-03-11 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion Added DEFINITION Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
2008-03-11 GO:0000437 carbon catabolite repression of transcription from RNA polymerase II promoter Updated DEFINITION Any process involving carbon catabolites that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2008-03-11 GO:0045902 negative regulation of translational fidelity Updated DEFINITION Any process that decreases the ability of the translational apparatus to interpret the genetic code.
2008-03-11 GO:0010529 negative regulation of transposition Added DEFINITION Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
2008-03-11 GO:0010526 negative regulation of transposition, RNA-mediated Added DEFINITION Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
2008-03-11 GO:0010554 neurotransmitter secretory pathway Added DEFINITION A regulated secretory pathway in which neurotransmitters are initially stored in secretory vesicles for later release.
2008-03-11 GO:0034258 nicotinamide riboside transport Added DEFINITION The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of, within or between cells.
2008-03-11 GO:0034257 nicotinamide riboside transmembrane transporter activity Added DEFINITION Catalysis of the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.
2008-03-11 GO:0001865 NK T cell differentiation Updated DEFINITION The process whereby a precursor cell type acquires the specialized features of a NK T cell.
2008-03-11 GO:0060227 Notch signaling pathway involved in camera-type eye photoreceptor fate commitment Added DEFINITION The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.
2008-03-11 GO:0000389 mRNA 3'-splice site recognition Updated DEFINITION Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.
2008-03-11 GO:0033171 nucleoprotein filament-forming ATPase activity Updated DEFINITION OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament.
2008-03-11 GO:0046173 polyol biosynthetic process Added SYNONYM polyhydric alcohol biosynthetic process
2008-03-11 GO:0046174 polyol catabolic process Added SYNONYM polyhydric alcohol catabolic process
2008-03-11 GO:0030436 asexual sporulation Deleted SYNONYM spore formation (sensu Bacteria)
2008-03-11 GO:0030437 ascospore formation Deleted SYNONYM ascospore formation
2008-03-11 GO:0030437 ascospore formation Deleted SYNONYM spore formation (sensu Fungi)
2008-03-11 GO:0042764 ascospore-type prospore Deleted SYNONYM forespore (sensu Fungi)
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Deleted SYNONYM spore wall chitin breakdown
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Deleted SYNONYM spore wall chitin catabolism
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Deleted SYNONYM spore wall chitin degradation
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Deleted SYNONYM regulation of spore wall chitin breakdown
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Deleted SYNONYM regulation of spore wall chitin catabolism
2008-03-11 GO:0042173 regulation of sporulation resulting in formation of a cellular spore Deleted SYNONYM MAPKKK cascade during sporulation (sensu Fungi)
2008-03-11 GO:0042173 regulation of sporulation resulting in formation of a cellular spore Deleted SYNONYM MAPKKK cascade during sporulation (sensu Saccharomyces)
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin synthesis
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin anabolism
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin biosynthesis
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin formation
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Deleted SYNONYM regulation of spore wall chitin synthesis
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Deleted SYNONYM regulation of spore wall chitin degradation
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin anabolism
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin biosynthesis
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Deleted SYNONYM spore wall chitin formation
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Deleted SYNONYM spore wall chitin metabolism
2008-03-11 GO:0019751 polyol metabolic process Added SYNONYM polyhydric alcohol metabolic process
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM asexual spore formation
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM mitotic spore formation
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM mitotic sporulation
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM spore formation (sensu Bacteria)
2008-03-11 GO:0030436 asexual sporulation Added SYNONYM sporulation (sensu Bacteria)
2008-03-11 GO:0030437 ascospore formation Added SYNONYM spore formation (sensu Fungi)
2008-03-11 GO:0030437 ascospore formation Added SYNONYM sporulation (sensu Fungi)
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin anabolism
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin biosynthesis
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin formation
2008-03-11 GO:0034217 ascospore wall chitin biosynthetic process Added SYNONYM ascospore wall chitin synthesis
2008-03-11 GO:0034218 ascospore wall chitin metabolic process Added SYNONYM ascospore wall chitin metabolism
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin anabolism
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin biosynthesis
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin formation
2008-03-11 GO:0034223 regulation of ascospore wall chitin biosynthetic process Added SYNONYM regulation of ascospore wall chitin synthesis
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added SYNONYM ascospore wall chitin breakdown
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added SYNONYM ascospore wall chitin catabolism
2008-03-11 GO:0034232 ascospore wall chitin catabolic process Added SYNONYM ascospore wall chitin degradation
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added SYNONYM regulation of ascospore wall chitin breakdown
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added SYNONYM regulation of ascospore wall chitin catabolism
2008-03-11 GO:0034234 regulation of ascospore wall chitin catabolic process Added SYNONYM regulation of ascospore wall chitin degradation
2008-03-11 GO:0034293 sexual sporulation Added SYNONYM meiotic spore formation
2008-03-11 GO:0034293 sexual sporulation Added SYNONYM meiotic sporulation
2008-03-11 GO:0034293 sexual sporulation Added SYNONYM sexual spore formation
2008-03-11 GO:0034294 sexual spore wall assembly Added SYNONYM sexual spore wall formation
2008-03-11 GO:0034307 regulation of ascospore formation Added SYNONYM MAPKKK cascade during sporulation (sensu Saccharomyces)
2008-03-11 GO:0034308 primary alcohol metabolic process Added SYNONYM monohydric alcohol metabolism
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol anabolism
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol biosynthesis
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol formation
2008-03-11 GO:0034309 primary alcohol biosynthetic process Added SYNONYM monohydric alcohol synthesis
2008-03-11 GO:0034310 primary alcohol catabolic process Added SYNONYM monohydric alcohol breakdown
2008-03-11 GO:0034310 primary alcohol catabolic process Added SYNONYM monohydric alcohol catabolism
2008-03-11 GO:0034310 primary alcohol catabolic process Added SYNONYM monohydric alcohol degradation
2008-03-11 GO:0034311 diol metabolic process Added SYNONYM dihydric alcohol metabolic process
2008-03-11 GO:0034311 diol metabolic process Added SYNONYM diol metabolism
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM dihydric alcohol biosynthetic process
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol anabolism
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol biosynthesis
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol formation
2008-03-11 GO:0034312 diol biosynthetic process Added SYNONYM diol synthesis
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM dihydric alcohol catabolic process
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM diol breakdown
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM diol catabolism
2008-03-11 GO:0034313 diol catabolic process Added SYNONYM diol degradation
2008-03-11 GO:0042243 asexual spore wall assembly Added SYNONYM asexual spore wall formation
2008-03-11 GO:0042243 asexual spore wall assembly Added SYNONYM spore wall assembly (sensu Bacteria)
2008-03-11 GO:0042244 spore wall assembly Added SYNONYM spore wall formation
2008-03-11 GO:0042764 ascospore-type prospore Added SYNONYM forespore (sensu Fungi)
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