spacer

GO Term History: Displaying 22 audit records for all terms for the date 2006-11-21

From (YYYY-MM-DD):
To (YYYY-MM-DD):
Period:
Category:
Terms:
Limit:
Date Specification

You can specify an explicit date range that you are interested in by setting the "From" and "To" parameters; this will limit the data displayed to those changes that were recorded within that (inclusive) date range.

Alternatively, you can use the "Period" parameter to view the GO term changes that occurred over a specific number of Day(s), Week(s), Month(s) or Year(s) before a specified date.

If you do not enter a "To" date, then the period will be relative to the current date. If, however, you do specify a "To" value, then the "Period" value will display records in the timeframe up to and including that specified date.

Category

You can use this field to specify what types of term changes you are interested in seeing.

Terms

You can enter a list of GO Terms in this field to limit the changes displayed. Please note that only changes made to directly listed terms will be displayed, not term descendants.

Limit

The default number of records returned is 500, however you can increase or decrease this limit. In order to prevent possible browser problems, the maximum upper limit is 10,000.

Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-11-21 GO:0032393 MHC class I receptor activity Added DEFINITION Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.
2006-11-21 GO:0032398 MHC class Ib protein complex Added DEFINITION A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
2006-11-21 GO:0032394 MHC class Ib receptor activity Added DEFINITION Combining with an MHC class Ib protein complex to initiate a change in cellular activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
2006-11-21 GO:0042613 MHC class II protein complex Updated DEFINITION A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.
2006-11-21 GO:0032395 MHC class II receptor activity Added DEFINITION Combining with an MHC class II protein complex to initiate a change in cellular activity.
2006-11-21 GO:0045012 MHC class II receptor activity Updated DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2006-11-21 GO:0042611 MHC protein complex Updated DEFINITION A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen
2006-11-21 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2006-11-21 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2006-11-21 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2006-11-21 GO:0032397 activating MHC class I receptor activity Added DEFINITION Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
2006-11-21 GO:0004034 aldose 1-epimerase activity Updated DEFINITION Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.
2006-11-21 GO:0032437 cuticular plate Added DEFINITION A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
2006-11-21 GO:0032439 endosome localization Added DEFINITION The processes by which endosomes are transported to, and/or maintained in, a specific location within the cell.
2006-11-21 GO:0032433 filopodium tip Added DEFINITION The end of a filopodium distal to the body of the cell.
2006-11-21 GO:0030108 HLA-A specific activating MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.
2006-11-21 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0030110 HLA-C specific inhibitory MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0032396 inhibitory MHC class I receptor activity Added DEFINITION Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0032438 melanosome organization Added DEFINITION The assembly and arrangement of a melanosome.
2006-11-21 GO:0042612 MHC class I protein complex Updated DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-11-21 GO:0032393 MHC class I receptor activity Added DEFINITION Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.
2006-11-21 GO:0032398 MHC class Ib protein complex Added DEFINITION A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
2006-11-21 GO:0032394 MHC class Ib receptor activity Added DEFINITION Combining with an MHC class Ib protein complex to initiate a change in cellular activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
2006-11-21 GO:0042613 MHC class II protein complex Updated DEFINITION A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.
2006-11-21 GO:0032395 MHC class II receptor activity Added DEFINITION Combining with an MHC class II protein complex to initiate a change in cellular activity.
2006-11-21 GO:0045012 MHC class II receptor activity Updated DEFINITION OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
2006-11-21 GO:0042611 MHC protein complex Updated DEFINITION A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen
2006-11-21 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2006-11-21 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2006-11-21 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2006-11-21 GO:0032397 activating MHC class I receptor activity Added DEFINITION Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
2006-11-21 GO:0004034 aldose 1-epimerase activity Updated DEFINITION Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.
2006-11-21 GO:0032437 cuticular plate Added DEFINITION A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
2006-11-21 GO:0032439 endosome localization Added DEFINITION The processes by which endosomes are transported to, and/or maintained in, a specific location within the cell.
2006-11-21 GO:0032433 filopodium tip Added DEFINITION The end of a filopodium distal to the body of the cell.
2006-11-21 GO:0030108 HLA-A specific activating MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.
2006-11-21 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0030110 HLA-C specific inhibitory MHC class I receptor activity Updated DEFINITION Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0032396 inhibitory MHC class I receptor activity Added DEFINITION Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.
2006-11-21 GO:0032438 melanosome organization Added DEFINITION The assembly and arrangement of a melanosome.
2006-11-21 GO:0042612 MHC class I protein complex Updated DEFINITION A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
110ms