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GO Term History: Displaying 36 audit records for all terms for the date 2006-11-07

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-11-07 GO:0032407 MutSalpha complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutSalpha.
2006-11-07 GO:0032408 MutSbeta complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutSbeta.
2006-11-07 GO:0055026 negative regulation of cardiac muscle tissue development Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle development.
2006-11-07 GO:0055019 negative regulation of cardiac muscle fiber development Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle fiber development.
2006-11-07 GO:0055022 negative regulation of cardiac muscle tissue growth Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle growth.
2006-11-07 GO:0005042 netrin receptor activity Added DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemotaxis when activated.
2006-11-07 GO:0060002 plus-end directed microfilament motor activity Added DEFINITION Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers.
2006-11-07 GO:0008267 poly-glutamine tract binding Added DEFINITION Interacting selectively with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein.
2006-11-07 GO:0002094 polyprenyltransferase activity Added DEFINITION Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).
2006-11-07 GO:0055025 positive regulation of cardiac muscle tissue development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle development.
2006-11-07 GO:0055020 positive regulation of cardiac muscle fiber development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.
2006-11-07 GO:0055023 positive regulation of cardiac muscle tissue growth Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.
2006-11-07 GO:0032403 protein complex binding Added DEFINITION Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2006-11-07 GO:0055024 regulation of cardiac muscle tissue development Added DEFINITION Any process that modulates the frequency, rate or extent of cardiac muscle development.
2006-11-07 GO:0055018 regulation of cardiac muscle fiber development Added DEFINITION Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.
2006-11-07 GO:0055021 regulation of cardiac muscle tissue growth Added DEFINITION Any process that modulates the frequency, rate or extent of cardiac muscle growth.
2006-11-07 GO:0005043 netrin receptor activity involved in chemorepulsion Added DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemorepulsion when activated.
2006-11-07 GO:0032405 MutLalpha complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutLalpha.
2006-11-07 GO:0032406 MutLbeta complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutLbeta.
2006-11-07 GO:0005736 DNA-directed RNA polymerase I complex Updated DEFINITION RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
2006-11-07 GO:0005665 DNA-directed RNA polymerase II, core complex Updated DEFINITION RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
2006-11-07 GO:0005666 DNA-directed RNA polymerase III complex Updated DEFINITION RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
2006-11-07 GO:0046536 dosage compensation complex Updated DEFINITION A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes.
2006-11-07 GO:0032401 establishment of melanosome localization Added DEFINITION The directed movement of a melanosome to a specific location.
2006-11-07 GO:0032399 HECT domain binding Added DEFINITION Interacting selectively with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein.
2006-11-07 GO:0032400 melanosome localization Added DEFINITION The processes by which a melanosome is transported to, and/or maintained in, a specific location within the cell.
2006-11-07 GO:0032402 melanosome transport Added DEFINITION The directed movement of melanosomes into, out of, within or between cells.
2006-11-07 GO:0060001 minus-end directed microfilament motor activity Added DEFINITION Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers.
2006-11-07 GO:0032404 mismatch repair complex binding Added DEFINITION Interacting selectively with a mismatch repair complex.
2006-11-07 GO:0019008 molybdopterin synthase complex Added DEFINITION A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.
2006-11-07 GO:0030681 multimeric ribonuclease P complex Updated DEFINITION A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules.
2006-11-07 GO:0060003 copper ion export Added DEFINITION The directed movement of copper ions out of a cell or organelle.
2006-11-07 GO:0030680 dimeric ribonuclease P complex Updated DEFINITION A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule.
2006-11-07 GO:0032392 DNA geometric change Added DEFINITION The process by which a transformation is induced in the geometry of a DNA double helix, resulting in a change twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
2006-11-07 GO:0031556 transcriptional attenuation by ribosome Updated DEFINITION A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as availabe amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.
2006-11-07 GO:0046215 siderophore catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-11-07 GO:0032407 MutSalpha complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutSalpha.
2006-11-07 GO:0032408 MutSbeta complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutSbeta.
2006-11-07 GO:0055026 negative regulation of cardiac muscle tissue development Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle development.
2006-11-07 GO:0055019 negative regulation of cardiac muscle fiber development Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle fiber development.
2006-11-07 GO:0055022 negative regulation of cardiac muscle tissue growth Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle growth.
2006-11-07 GO:0005042 netrin receptor activity Added DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemotaxis when activated.
2006-11-07 GO:0060002 plus-end directed microfilament motor activity Added DEFINITION Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers.
2006-11-07 GO:0008267 poly-glutamine tract binding Added DEFINITION Interacting selectively with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein.
2006-11-07 GO:0002094 polyprenyltransferase activity Added DEFINITION Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).
2006-11-07 GO:0055025 positive regulation of cardiac muscle tissue development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle development.
2006-11-07 GO:0055020 positive regulation of cardiac muscle fiber development Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.
2006-11-07 GO:0055023 positive regulation of cardiac muscle tissue growth Added DEFINITION Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.
2006-11-07 GO:0032403 protein complex binding Added DEFINITION Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2006-11-07 GO:0055024 regulation of cardiac muscle tissue development Added DEFINITION Any process that modulates the frequency, rate or extent of cardiac muscle development.
2006-11-07 GO:0055018 regulation of cardiac muscle fiber development Added DEFINITION Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.
2006-11-07 GO:0055021 regulation of cardiac muscle tissue growth Added DEFINITION Any process that modulates the frequency, rate or extent of cardiac muscle growth.
2006-11-07 GO:0005043 netrin receptor activity involved in chemorepulsion Added DEFINITION A transmembrane receptor activity that responds to the netrin family of ligands and results in chemorepulsion when activated.
2006-11-07 GO:0032405 MutLalpha complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutLalpha.
2006-11-07 GO:0032406 MutLbeta complex binding Added DEFINITION Interacting selectively with the mismatch repair complex MutLbeta.
2006-11-07 GO:0005736 DNA-directed RNA polymerase I complex Updated DEFINITION RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
2006-11-07 GO:0005665 DNA-directed RNA polymerase II, core complex Updated DEFINITION RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
2006-11-07 GO:0005666 DNA-directed RNA polymerase III complex Updated DEFINITION RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
2006-11-07 GO:0046536 dosage compensation complex Updated DEFINITION A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes.
2006-11-07 GO:0032401 establishment of melanosome localization Added DEFINITION The directed movement of a melanosome to a specific location.
2006-11-07 GO:0032399 HECT domain binding Added DEFINITION Interacting selectively with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein.
2006-11-07 GO:0032400 melanosome localization Added DEFINITION The processes by which a melanosome is transported to, and/or maintained in, a specific location within the cell.
2006-11-07 GO:0032402 melanosome transport Added DEFINITION The directed movement of melanosomes into, out of, within or between cells.
2006-11-07 GO:0060001 minus-end directed microfilament motor activity Added DEFINITION Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers.
2006-11-07 GO:0032404 mismatch repair complex binding Added DEFINITION Interacting selectively with a mismatch repair complex.
2006-11-07 GO:0019008 molybdopterin synthase complex Added DEFINITION A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.
2006-11-07 GO:0030681 multimeric ribonuclease P complex Updated DEFINITION A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules.
2006-11-07 GO:0060003 copper ion export Added DEFINITION The directed movement of copper ions out of a cell or organelle.
2006-11-07 GO:0030680 dimeric ribonuclease P complex Updated DEFINITION A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule.
2006-11-07 GO:0032392 DNA geometric change Added DEFINITION The process by which a transformation is induced in the geometry of a DNA double helix, resulting in a change twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
2006-11-07 GO:0031556 transcriptional attenuation by ribosome Updated DEFINITION A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as availabe amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.
2006-11-07 GO:0046215 siderophore catabolic process Updated DEFINITION The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
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