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GO Term History: Displaying 169 audit records for all terms for the date 2006-10-21

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-10-21 GO:0032331 negative regulation of chondrocyte differentiation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte differentiation.
2006-10-21 GO:0032353 negative regulation of hormone biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
2006-10-21 GO:0032351 negative regulation of hormone metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
2006-10-21 GO:0032339 negative regulation of inhibin secretion Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells.
2006-10-21 GO:0032384 negative regulation of intracellular cholesterol transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.
2006-10-21 GO:0032378 negative regulation of intracellular lipid transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.
2006-10-21 GO:0032381 negative regulation of intracellular sterol transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.
2006-10-21 GO:0032387 negative regulation of intracellular transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
2006-10-21 GO:0032369 negative regulation of lipid transport Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells.
2006-10-21 GO:0002091 negative regulation of receptor internalization Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of receptor internalization.
2006-10-21 GO:0032372 negative regulation of sterol transport Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells.
2006-10-21 GO:0048885 neuromast deposition Added DEFINITION The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.
2006-10-21 GO:0021845 neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration Updated DEFINITION The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.
2006-10-21 GO:0048242 epinephrine secretion Updated DEFINITION The regulated release of epinephrine by a cell or group of cells. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.
2006-10-21 GO:0035101 FACT complex Updated DEFINITION An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer.
2006-10-21 GO:0032362 FAD catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
2006-10-21 GO:0032363 FMN catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
2006-10-21 GO:0004963 follicle-stimulating hormone receptor activity Updated DEFINITION Combining with follicle-stimulating hormone to initiate a change in cell activity.
2006-10-21 GO:0042699 follicle-stimulating hormone signaling pathway Updated DEFINITION The series of molecular signals mediated by follicle-stimulating hormone.
2006-10-21 GO:0048933 afferent axon development in posterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.
2006-10-21 GO:0032342 aldosterone biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
2006-10-21 GO:0032343 aldosterone catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
2006-10-21 GO:0032341 aldosterone metabolic process Added DEFINITION The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
2006-10-21 GO:0048899 anterior lateral line development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.
2006-10-21 GO:0048907 anterior lateral line ganglion development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.
2006-10-21 GO:0048908 anterior lateral line ganglion neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.
2006-10-21 GO:0048909 anterior lateral line nerve development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
2006-10-21 GO:0048939 anterior lateral line nerve glial cell development Added DEFINITION The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-10-21 GO:0048913 anterior lateral line nerve glial cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.
2006-10-21 GO:0048940 anterior lateral line nerve glial cell morphogenesis involved in differentiation Added DEFINITION The process by which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initally relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.
2006-10-21 GO:0048904 anterior lateral line neuromast cupula development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
2006-10-21 GO:0048902 anterior lateral line neuromast deposition Added DEFINITION The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.
2006-10-21 GO:0048901 anterior lateral line neuromast development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
2006-10-21 GO:0048903 anterior lateral line neuromast hair cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2006-10-21 GO:0048905 anterior lateral line neuromast mantle cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2006-10-21 GO:0048900 anterior lateral line neuromast primordium migration Added DEFINITION The migration of a cluster of relatively undifferentiated cells along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
2006-10-21 GO:0048906 anterior lateral line neuromast support cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2006-10-21 GO:0048898 anterior lateral line system development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
2006-10-21 GO:0005575 cellular_component Updated DEFINITION The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
2006-10-21 GO:0010277 chlorophyllide a oxygenase [overall] activity Added DEFINITION Catalysis of the reaction: chlorophyllide a + O2 + NADP+ + H+ = chlorophyllide b + H2O + NADPH + H+.
2006-10-21 GO:0010278 chloroplast outer membrane translocon Added DEFINITION The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.
2006-10-21 GO:0032154 cleavage furrow Updated DEFINITION In animal cells, the first sign of cleavage, or cytokinesis, is the appearance of a shallow groove in the cell surface near the old metaphase plate. A contractile ring containing actin and myosin, is located just inside the plasma membrane at the location of the furrow. Ring contraction is associated with centripetal growth of the membrane that deepens the cleavage furrow and divides the cytoplasm of the two daughter cells. While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists.
2006-10-21 GO:0048887 cupula development Added DEFINITION The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
2006-10-21 GO:0021700 developmental maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
2006-10-21 GO:0010285 L,L-diaminopimelate aminotransferase activity Added DEFINITION Catalysis of the reaction: tetrahydrodipicolinate + glutamate = L,L-diaminopimelate + 2-oxoglutarate.
2006-10-21 GO:0010284 lariciresinol reductase activity Added DEFINITION Catalysis of the reaction: lariciresinol + NADPH = secoisolariciresinol + NADP+.
2006-10-21 GO:0048882 lateral line development Added DEFINITION The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.
2006-10-21 GO:0048890 lateral line ganglion development Added DEFINITION The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.
2006-10-21 GO:0048891 lateral line ganglion neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.
2006-10-21 GO:0048892 lateral line nerve development Added DEFINITION The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
2006-10-21 GO:0048937 lateral line nerve glial cell development Added DEFINITION The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-10-21 GO:0048895 lateral line nerve glial cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.
2006-10-21 GO:0048938 lateral line nerve glial cell morphogenesis involved in differentiation Added DEFINITION The process by which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initally relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.
2006-10-21 GO:0048925 lateral line system development Added DEFINITION The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.
2006-10-21 GO:0002088 lens development in camera-type eye Added DEFINITION The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. As in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2006-10-21 GO:0002089 lens morphogenesis in camera-type eye Added DEFINITION The process by which the anatomical structures of the lens are generated and organized. Morphogenesis pertains to the creation of form. The lens is a transparent structure in the eye through which light is focused onto the retina. As in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2006-10-21 GO:0042062 long-term strengthening of neuromuscular junction Added DEFINITION Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.
2006-10-21 GO:0048881 mechanosensory lateral line system development Added DEFINITION The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
2006-10-21 GO:0032389 MutLalpha complex Added DEFINITION A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
2006-10-21 GO:0032390 MutLbeta complex Added DEFINITION A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.
2006-10-21 GO:0032301 MutSalpha complex Updated DEFINITION A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.
2006-10-21 GO:0032288 myelin assembly Updated DEFINITION The process by which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.
2006-10-21 GO:0032289 central nervous system myelin formation Updated DEFINITION The process by which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.
2006-10-21 GO:0032290 peripheral nervous system myelin formation Updated DEFINITION The process by which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system.
2006-10-21 GO:0048914 myelination of anterior lateral line nerve axons Added DEFINITION The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.
2006-10-21 GO:0048897 myelination of lateral line nerve axons Added DEFINITION The formation of compact myelin sheaths around the axons of a lateral line nerve.
2006-10-21 GO:0048932 myelination of posterior lateral line nerve axons Added DEFINITION The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.
2006-10-21 GO:0032336 negative regulation of activin secretion Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of activin from a cell or group of cells.
2006-10-21 GO:0032348 negative regulation of aldosterone biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
2006-10-21 GO:0032345 negative regulation of aldosterone metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
2006-10-21 GO:0032375 negative regulation of cholesterol transport Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells.
2006-10-21 GO:0032359 provirus excision Added DEFINITION The molecular events that lead to the excision of a viral genome from the host genome.
2006-10-21 GO:0032360 provirus maintenance Added DEFINITION The molecular events that maintain a viral genome integrated into a host genome.
2006-10-21 GO:0010280 UDP-L-rhamnose synthase activity Added DEFINITION Catalysis of the reaction UDP-D-glucose + NADPH = UDP-L-rhamnose + NADP+ + H2O.
2006-10-21 GO:0032382 positive regulation of intracellular sterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.
2006-10-21 GO:0032388 positive regulation of intracellular transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
2006-10-21 GO:0032370 positive regulation of lipid transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells.
2006-10-21 GO:0002092 positive regulation of receptor internalization Added DEFINITION Any process that activates or increases the frequency, rate or extent of receptor internalization.
2006-10-21 GO:0032373 positive regulation of sterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells.
2006-10-21 GO:0048916 posterior lateral line development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.
2006-10-21 GO:0048917 posterior lateral line ganglion development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.
2006-10-21 GO:0048928 posterior lateral line ganglion neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.
2006-10-21 GO:0048918 posterior lateral line nerve development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line nerve over time, form its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
2006-10-21 GO:0048941 posterior lateral line nerve glial cell development Added DEFINITION The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-10-21 GO:0048931 posterior lateral line nerve glial cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.
2006-10-21 GO:0048942 posterior lateral line nerve glial cell morphogenesis involved in differentiation Added DEFINITION The process by which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initally relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.
2006-10-21 GO:0048921 posterior lateral line neuromast cupula development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
2006-10-21 GO:0048922 posterior lateral line neuromast deposition Added DEFINITION The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.
2006-10-21 GO:0048919 posterior lateral line neuromast development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
2006-10-21 GO:0048923 posterior lateral line neuromast hair cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2006-10-21 GO:0032280 symmetric synapse Updated DEFINITION A type of synapse occurring primarily on dendrite shafts and neuronal cell bodies. Symmetric synapses involve axons containing clusters of predominantly flattened or elongated vesicles and do not contain a prominent postsynaptic density.
2006-10-21 GO:0016564 transcription repressor activity Added DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2006-10-21 GO:0032346 positive regulation of aldosterone metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
2006-10-21 GO:0032376 positive regulation of cholesterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells.
2006-10-21 GO:0032332 positive regulation of chondrocyte differentiation Added DEFINITION Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.
2006-10-21 GO:0032352 positive regulation of hormone metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
2006-10-21 GO:0032340 positive regulation of inhibin secretion Added DEFINITION Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells.
2006-10-21 GO:0032385 positive regulation of intracellular cholesterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.
2006-10-21 GO:0032379 positive regulation of intracellular lipid transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.
2006-10-21 GO:0016565 general transcriptional repressor activity Added DEFINITION Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set.
2006-10-21 GO:0048896 lateral line nerve glial cell migration Added DEFINITION The movement of glial cells along the axons in a lateral line nerve.
2006-10-21 GO:0048912 glial cell migration in anterior lateral line nerve Added DEFINITION The movement of glial cells along the axons in the anterior lateral line nerve.
2006-10-21 GO:0048930 glial cell migration in posterior lateral line nerve Added DEFINITION The movement of glial cells along the axons in the posterior lateral line nerve.
2006-10-21 GO:0051448 gonadotropin-releasing hormone binding Updated DEFINITION Interacting selectively with gonadotropin-releasing hormone, a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary and it is synthesized and released by the hypothalamus.
2006-10-21 GO:0031530 gonadotropin-releasing hormone receptor binding Updated DEFINITION Interacting selectively with a receptor for gonadotropin-releasing hormone, a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
2006-10-21 GO:0010279 indole-3-acetic acid amido synthetase activity Added DEFINITION Catalysis of the reaction IAA + an amino acid = an IAA amide conjugate.
2006-10-21 GO:0032334 inhibin secretion Added DEFINITION The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.
2006-10-21 GO:0032367 intracellular cholesterol transport Added DEFINITION The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.
2006-10-21 GO:0032365 intracellular lipid transport Added DEFINITION The directed movement of lipids within cells.
2006-10-21 GO:0032366 intracellular sterol transport Added DEFINITION The directed movement of sterols within cells.
2006-10-21 GO:0006265 DNA topological change Updated DEFINITION The process by which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
2006-10-21 GO:0014046 dopamine secretion Updated DEFINITION The regulated release of dopamine by a cell or group of cells. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.
2006-10-21 GO:0048894 efferent axon development in a lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.
2006-10-21 GO:0048911 efferent axon development in anterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.
2006-10-21 GO:0048929 efferent axon development in posterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.
2006-10-21 GO:0048926 electrosensory lateral line system development Added DEFINITION The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.
2006-10-21 GO:0032333 activin secretion Added DEFINITION The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.
2006-10-21 GO:0010281 acyl-ACP thioesterase activity Added DEFINITION Catalysis of the reaction: acyl-ACP + H2O = a fatty acid + ACP.
2006-10-21 GO:0048893 afferent axon development in lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.
2006-10-21 GO:0048910 afferent axon development in anterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.
2006-10-21 GO:0032330 regulation of chondrocyte differentiation Added DEFINITION Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
2006-10-21 GO:0032350 regulation of hormone metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
2006-10-21 GO:0032338 regulation of inhibin secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells.
2006-10-21 GO:0032383 regulation of intracellular cholesterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
2006-10-21 GO:0032377 regulation of intracellular lipid transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.
2006-10-21 GO:0032380 regulation of intracellular sterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.
2006-10-21 GO:0032386 regulation of intracellular transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
2006-10-21 GO:0032368 regulation of lipid transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells.
2006-10-21 GO:0002090 regulation of receptor internalization Added DEFINITION Any process that modulates the frequency, rate or extent of receptor internalization.
2006-10-21 GO:0032371 regulation of sterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells.
2006-10-21 GO:0002237 response to molecule of bacterial origin Updated DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of bacterial associated molecules such as peptides derived from bacterial flagellin.
2006-10-21 GO:0032355 response to estradiol Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2006-10-21 GO:0032354 response to follicle-stimulating hormone Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
2006-10-21 GO:0002238 response to molecule of fungal origin Updated DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of fungal associated molecules such as chito-octomer oligosaccharide.
2006-10-21 GO:0002240 response to molecule of oomycetes origin Updated DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of oomycete associated molecules.
2006-10-21 GO:0032391 photoreceptor connecting cilium Added DEFINITION A 9+0 cilium that forms the portion of the axoneme traversing the boundary between the photoreceptor inner and outer segments.
2006-10-21 GO:0010276 phytol kinase activity Added DEFINITION Catalysis of the reaction: phytol + CTP = phytylphosphate + CDP.
2006-10-21 GO:0010283 pinoresinol reductase activity Added DEFINITION Catalysis of the reaction: pinoresinol + NADPH = lariciresinol + NADP+.
2006-10-21 GO:0032337 positive regulation of activin secretion Added DEFINITION Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell or group of cells.
2006-10-21 GO:0032349 positive regulation of aldosterone biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
2006-10-21 GO:0032358 oxidized pyrimidine DNA binding Added DEFINITION Interacting selectively with oxidized pyrimidine residues in DNA.
2006-10-21 GO:0032364 oxygen homeostasis Added DEFINITION Any of the processes involved in the maintenance of an internal equilibrium of oxygen within an organism or cell.
2006-10-21 GO:0048936 peripheral nervous system neuron axonogenesis Added DEFINITION Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.
2006-10-21 GO:0048935 peripheral nervous system neuron development Added DEFINITION The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
2006-10-21 GO:0048934 peripheral nervous system neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.
2006-10-21 GO:0045332 phospholipid translocation Updated DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2006-10-21 GO:0048884 neuromast development Added DEFINITION The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.
2006-10-21 GO:0048886 neuromast hair cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2006-10-21 GO:0048888 neuromast mantle cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2006-10-21 GO:0048883 neuromast primordium migration Added DEFINITION The migration of a cluster of relatively undifferentiated cells originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.
2006-10-21 GO:0048889 neuromast support cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2006-10-21 GO:0048243 norepinephrine secretion Updated DEFINITION The regulated release of norepinephrine by a cell or group of cells. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.
2006-10-21 GO:0048862 organ boundary specification Added DEFINITION The process by which boundaries between organs and the surrounding tissue are established and maintained.
2006-10-21 GO:0032356 oxidized DNA binding Added DEFINITION Interacting selectively with oxidized residues in DNA.
2006-10-21 GO:0010282 senescence-associated vacuole Added DEFINITION Vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.
2006-10-21 GO:0008052 sensory organ boundary specification Added DEFINITION The process by which boundaries between a sensory organ and the surrounding tissue are established and maintained.
2006-10-21 GO:0048880 sensory system development Added DEFINITION The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.
2006-10-21 GO:0016566 specific transcriptional repressor activity Added DEFINITION Any activity that stops or downregulates transcription of specific genes or sets of genes.
2006-10-21 GO:0048924 posterior lateral line neuromast mantle cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2006-10-21 GO:0048920 posterior lateral line neuromast primordium migration Added DEFINITION The migration of a cluster of relatively undifferentiated cells along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
2006-10-21 GO:0048927 posterior lateral line neuromast support cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2006-10-21 GO:0048915 posterior lateral line system development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
2006-10-21 GO:0014020 primary neural tube formation Updated DEFINITION The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.
2006-10-21 GO:0032357 oxidized purine DNA binding Added DEFINITION Interacting selectively with oxidized purine residues in DNA.
2006-10-21 GO:0032361 pyridoxal phosphate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
2006-10-21 GO:0032335 regulation of activin secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell or group of cells.
2006-10-21 GO:0032347 regulation of aldosterone biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
2006-10-21 GO:0032344 regulation of aldosterone metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
2006-10-21 GO:0032374 regulation of cholesterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-10-21 GO:0032331 negative regulation of chondrocyte differentiation Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte differentiation.
2006-10-21 GO:0032353 negative regulation of hormone biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
2006-10-21 GO:0032351 negative regulation of hormone metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
2006-10-21 GO:0032339 negative regulation of inhibin secretion Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells.
2006-10-21 GO:0032384 negative regulation of intracellular cholesterol transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.
2006-10-21 GO:0032378 negative regulation of intracellular lipid transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.
2006-10-21 GO:0032381 negative regulation of intracellular sterol transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.
2006-10-21 GO:0032387 negative regulation of intracellular transport Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
2006-10-21 GO:0032369 negative regulation of lipid transport Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells.
2006-10-21 GO:0002091 negative regulation of receptor internalization Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of receptor internalization.
2006-10-21 GO:0032372 negative regulation of sterol transport Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells.
2006-10-21 GO:0048885 neuromast deposition Added DEFINITION The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.
2006-10-21 GO:0021845 neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration Updated DEFINITION The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.
2006-10-21 GO:0048242 epinephrine secretion Updated DEFINITION The regulated release of epinephrine by a cell or group of cells. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.
2006-10-21 GO:0035101 FACT complex Updated DEFINITION An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer.
2006-10-21 GO:0032362 FAD catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
2006-10-21 GO:0032363 FMN catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
2006-10-21 GO:0004963 follicle-stimulating hormone receptor activity Updated DEFINITION Combining with follicle-stimulating hormone to initiate a change in cell activity.
2006-10-21 GO:0042699 follicle-stimulating hormone signaling pathway Updated DEFINITION The series of molecular signals mediated by follicle-stimulating hormone.
2006-10-21 GO:0048933 afferent axon development in posterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.
2006-10-21 GO:0032342 aldosterone biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
2006-10-21 GO:0032343 aldosterone catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
2006-10-21 GO:0032341 aldosterone metabolic process Added DEFINITION The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
2006-10-21 GO:0048899 anterior lateral line development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.
2006-10-21 GO:0048907 anterior lateral line ganglion development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.
2006-10-21 GO:0048908 anterior lateral line ganglion neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.
2006-10-21 GO:0048909 anterior lateral line nerve development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
2006-10-21 GO:0048939 anterior lateral line nerve glial cell development Added DEFINITION The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-10-21 GO:0048913 anterior lateral line nerve glial cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.
2006-10-21 GO:0048940 anterior lateral line nerve glial cell morphogenesis involved in differentiation Added DEFINITION The process by which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initally relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.
2006-10-21 GO:0048904 anterior lateral line neuromast cupula development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
2006-10-21 GO:0048902 anterior lateral line neuromast deposition Added DEFINITION The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.
2006-10-21 GO:0048901 anterior lateral line neuromast development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
2006-10-21 GO:0048903 anterior lateral line neuromast hair cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2006-10-21 GO:0048905 anterior lateral line neuromast mantle cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2006-10-21 GO:0048900 anterior lateral line neuromast primordium migration Added DEFINITION The migration of a cluster of relatively undifferentiated cells along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
2006-10-21 GO:0048906 anterior lateral line neuromast support cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2006-10-21 GO:0048898 anterior lateral line system development Added DEFINITION The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
2006-10-21 GO:0005575 cellular_component Updated DEFINITION The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
2006-10-21 GO:0010277 chlorophyllide a oxygenase [overall] activity Added DEFINITION Catalysis of the reaction: chlorophyllide a + O2 + NADP+ + H+ = chlorophyllide b + H2O + NADPH + H+.
2006-10-21 GO:0010278 chloroplast outer membrane translocon Added DEFINITION The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.
2006-10-21 GO:0032154 cleavage furrow Updated DEFINITION In animal cells, the first sign of cleavage, or cytokinesis, is the appearance of a shallow groove in the cell surface near the old metaphase plate. A contractile ring containing actin and myosin, is located just inside the plasma membrane at the location of the furrow. Ring contraction is associated with centripetal growth of the membrane that deepens the cleavage furrow and divides the cytoplasm of the two daughter cells. While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists.
2006-10-21 GO:0048887 cupula development Added DEFINITION The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
2006-10-21 GO:0021700 developmental maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
2006-10-21 GO:0010285 L,L-diaminopimelate aminotransferase activity Added DEFINITION Catalysis of the reaction: tetrahydrodipicolinate + glutamate = L,L-diaminopimelate + 2-oxoglutarate.
2006-10-21 GO:0010284 lariciresinol reductase activity Added DEFINITION Catalysis of the reaction: lariciresinol + NADPH = secoisolariciresinol + NADP+.
2006-10-21 GO:0048882 lateral line development Added DEFINITION The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.
2006-10-21 GO:0048890 lateral line ganglion development Added DEFINITION The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.
2006-10-21 GO:0048891 lateral line ganglion neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.
2006-10-21 GO:0048892 lateral line nerve development Added DEFINITION The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
2006-10-21 GO:0048937 lateral line nerve glial cell development Added DEFINITION The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-10-21 GO:0048895 lateral line nerve glial cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.
2006-10-21 GO:0048938 lateral line nerve glial cell morphogenesis involved in differentiation Added DEFINITION The process by which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initally relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.
2006-10-21 GO:0048925 lateral line system development Added DEFINITION The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.
2006-10-21 GO:0002088 lens development in camera-type eye Added DEFINITION The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. As in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2006-10-21 GO:0002089 lens morphogenesis in camera-type eye Added DEFINITION The process by which the anatomical structures of the lens are generated and organized. Morphogenesis pertains to the creation of form. The lens is a transparent structure in the eye through which light is focused onto the retina. As in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2006-10-21 GO:0042062 long-term strengthening of neuromuscular junction Added DEFINITION Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.
2006-10-21 GO:0048881 mechanosensory lateral line system development Added DEFINITION The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
2006-10-21 GO:0032389 MutLalpha complex Added DEFINITION A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
2006-10-21 GO:0032390 MutLbeta complex Added DEFINITION A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.
2006-10-21 GO:0032301 MutSalpha complex Updated DEFINITION A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.
2006-10-21 GO:0032288 myelin assembly Updated DEFINITION The process by which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.
2006-10-21 GO:0032289 central nervous system myelin formation Updated DEFINITION The process by which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.
2006-10-21 GO:0032290 peripheral nervous system myelin formation Updated DEFINITION The process by which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system.
2006-10-21 GO:0048914 myelination of anterior lateral line nerve axons Added DEFINITION The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.
2006-10-21 GO:0048897 myelination of lateral line nerve axons Added DEFINITION The formation of compact myelin sheaths around the axons of a lateral line nerve.
2006-10-21 GO:0048932 myelination of posterior lateral line nerve axons Added DEFINITION The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.
2006-10-21 GO:0032336 negative regulation of activin secretion Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of activin from a cell or group of cells.
2006-10-21 GO:0032348 negative regulation of aldosterone biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
2006-10-21 GO:0032345 negative regulation of aldosterone metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
2006-10-21 GO:0032375 negative regulation of cholesterol transport Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells.
2006-10-21 GO:0032359 provirus excision Added DEFINITION The molecular events that lead to the excision of a viral genome from the host genome.
2006-10-21 GO:0032360 provirus maintenance Added DEFINITION The molecular events that maintain a viral genome integrated into a host genome.
2006-10-21 GO:0010280 UDP-L-rhamnose synthase activity Added DEFINITION Catalysis of the reaction UDP-D-glucose + NADPH = UDP-L-rhamnose + NADP+ + H2O.
2006-10-21 GO:0032382 positive regulation of intracellular sterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.
2006-10-21 GO:0032388 positive regulation of intracellular transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
2006-10-21 GO:0032370 positive regulation of lipid transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells.
2006-10-21 GO:0002092 positive regulation of receptor internalization Added DEFINITION Any process that activates or increases the frequency, rate or extent of receptor internalization.
2006-10-21 GO:0032373 positive regulation of sterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells.
2006-10-21 GO:0048916 posterior lateral line development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.
2006-10-21 GO:0048917 posterior lateral line ganglion development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.
2006-10-21 GO:0048928 posterior lateral line ganglion neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.
2006-10-21 GO:0048918 posterior lateral line nerve development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line nerve over time, form its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
2006-10-21 GO:0048941 posterior lateral line nerve glial cell development Added DEFINITION The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-10-21 GO:0048931 posterior lateral line nerve glial cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.
2006-10-21 GO:0048942 posterior lateral line nerve glial cell morphogenesis involved in differentiation Added DEFINITION The process by which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initally relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.
2006-10-21 GO:0048921 posterior lateral line neuromast cupula development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
2006-10-21 GO:0048922 posterior lateral line neuromast deposition Added DEFINITION The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.
2006-10-21 GO:0048919 posterior lateral line neuromast development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
2006-10-21 GO:0048923 posterior lateral line neuromast hair cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2006-10-21 GO:0032280 symmetric synapse Updated DEFINITION A type of synapse occurring primarily on dendrite shafts and neuronal cell bodies. Symmetric synapses involve axons containing clusters of predominantly flattened or elongated vesicles and do not contain a prominent postsynaptic density.
2006-10-21 GO:0016564 transcription repressor activity Added DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2006-10-21 GO:0032346 positive regulation of aldosterone metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
2006-10-21 GO:0032376 positive regulation of cholesterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells.
2006-10-21 GO:0032332 positive regulation of chondrocyte differentiation Added DEFINITION Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.
2006-10-21 GO:0032352 positive regulation of hormone metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
2006-10-21 GO:0032340 positive regulation of inhibin secretion Added DEFINITION Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells.
2006-10-21 GO:0032385 positive regulation of intracellular cholesterol transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.
2006-10-21 GO:0032379 positive regulation of intracellular lipid transport Added DEFINITION Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.
2006-10-21 GO:0016565 general transcriptional repressor activity Added DEFINITION Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set.
2006-10-21 GO:0048896 lateral line nerve glial cell migration Added DEFINITION The movement of glial cells along the axons in a lateral line nerve.
2006-10-21 GO:0048912 glial cell migration in anterior lateral line nerve Added DEFINITION The movement of glial cells along the axons in the anterior lateral line nerve.
2006-10-21 GO:0048930 glial cell migration in posterior lateral line nerve Added DEFINITION The movement of glial cells along the axons in the posterior lateral line nerve.
2006-10-21 GO:0051448 gonadotropin-releasing hormone binding Updated DEFINITION Interacting selectively with gonadotropin-releasing hormone, a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary and it is synthesized and released by the hypothalamus.
2006-10-21 GO:0031530 gonadotropin-releasing hormone receptor binding Updated DEFINITION Interacting selectively with a receptor for gonadotropin-releasing hormone, a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
2006-10-21 GO:0010279 indole-3-acetic acid amido synthetase activity Added DEFINITION Catalysis of the reaction IAA + an amino acid = an IAA amide conjugate.
2006-10-21 GO:0032334 inhibin secretion Added DEFINITION The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.
2006-10-21 GO:0032367 intracellular cholesterol transport Added DEFINITION The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.
2006-10-21 GO:0032365 intracellular lipid transport Added DEFINITION The directed movement of lipids within cells.
2006-10-21 GO:0032366 intracellular sterol transport Added DEFINITION The directed movement of sterols within cells.
2006-10-21 GO:0006265 DNA topological change Updated DEFINITION The process by which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
2006-10-21 GO:0014046 dopamine secretion Updated DEFINITION The regulated release of dopamine by a cell or group of cells. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.
2006-10-21 GO:0048894 efferent axon development in a lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.
2006-10-21 GO:0048911 efferent axon development in anterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.
2006-10-21 GO:0048929 efferent axon development in posterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.
2006-10-21 GO:0048926 electrosensory lateral line system development Added DEFINITION The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.
2006-10-21 GO:0032333 activin secretion Added DEFINITION The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.
2006-10-21 GO:0010281 acyl-ACP thioesterase activity Added DEFINITION Catalysis of the reaction: acyl-ACP + H2O = a fatty acid + ACP.
2006-10-21 GO:0048893 afferent axon development in lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.
2006-10-21 GO:0048910 afferent axon development in anterior lateral line nerve Added DEFINITION The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.
2006-10-21 GO:0032330 regulation of chondrocyte differentiation Added DEFINITION Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
2006-10-21 GO:0032350 regulation of hormone metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
2006-10-21 GO:0032338 regulation of inhibin secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells.
2006-10-21 GO:0032383 regulation of intracellular cholesterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
2006-10-21 GO:0032377 regulation of intracellular lipid transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.
2006-10-21 GO:0032380 regulation of intracellular sterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.
2006-10-21 GO:0032386 regulation of intracellular transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
2006-10-21 GO:0032368 regulation of lipid transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of, within or between cells.
2006-10-21 GO:0002090 regulation of receptor internalization Added DEFINITION Any process that modulates the frequency, rate or extent of receptor internalization.
2006-10-21 GO:0032371 regulation of sterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of, within or between cells.
2006-10-21 GO:0002237 response to molecule of bacterial origin Updated DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of bacterial associated molecules such as peptides derived from bacterial flagellin.
2006-10-21 GO:0032355 response to estradiol Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2006-10-21 GO:0032354 response to follicle-stimulating hormone Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
2006-10-21 GO:0002238 response to molecule of fungal origin Updated DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of fungal associated molecules such as chito-octomer oligosaccharide.
2006-10-21 GO:0002240 response to molecule of oomycetes origin Updated DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of oomycete associated molecules.
2006-10-21 GO:0032391 photoreceptor connecting cilium Added DEFINITION A 9+0 cilium that forms the portion of the axoneme traversing the boundary between the photoreceptor inner and outer segments.
2006-10-21 GO:0010276 phytol kinase activity Added DEFINITION Catalysis of the reaction: phytol + CTP = phytylphosphate + CDP.
2006-10-21 GO:0010283 pinoresinol reductase activity Added DEFINITION Catalysis of the reaction: pinoresinol + NADPH = lariciresinol + NADP+.
2006-10-21 GO:0032337 positive regulation of activin secretion Added DEFINITION Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell or group of cells.
2006-10-21 GO:0032349 positive regulation of aldosterone biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
2006-10-21 GO:0032358 oxidized pyrimidine DNA binding Added DEFINITION Interacting selectively with oxidized pyrimidine residues in DNA.
2006-10-21 GO:0032364 oxygen homeostasis Added DEFINITION Any of the processes involved in the maintenance of an internal equilibrium of oxygen within an organism or cell.
2006-10-21 GO:0048936 peripheral nervous system neuron axonogenesis Added DEFINITION Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.
2006-10-21 GO:0048935 peripheral nervous system neuron development Added DEFINITION The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
2006-10-21 GO:0048934 peripheral nervous system neuron differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.
2006-10-21 GO:0045332 phospholipid translocation Updated DEFINITION The translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
2006-10-21 GO:0048884 neuromast development Added DEFINITION The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.
2006-10-21 GO:0048886 neuromast hair cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
2006-10-21 GO:0048888 neuromast mantle cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2006-10-21 GO:0048883 neuromast primordium migration Added DEFINITION The migration of a cluster of relatively undifferentiated cells originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.
2006-10-21 GO:0048889 neuromast support cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2006-10-21 GO:0048243 norepinephrine secretion Updated DEFINITION The regulated release of norepinephrine by a cell or group of cells. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.
2006-10-21 GO:0048862 organ boundary specification Added DEFINITION The process by which boundaries between organs and the surrounding tissue are established and maintained.
2006-10-21 GO:0032356 oxidized DNA binding Added DEFINITION Interacting selectively with oxidized residues in DNA.
2006-10-21 GO:0010282 senescence-associated vacuole Added DEFINITION Vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.
2006-10-21 GO:0008052 sensory organ boundary specification Added DEFINITION The process by which boundaries between a sensory organ and the surrounding tissue are established and maintained.
2006-10-21 GO:0048880 sensory system development Added DEFINITION The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.
2006-10-21 GO:0016566 specific transcriptional repressor activity Added DEFINITION Any activity that stops or downregulates transcription of specific genes or sets of genes.
2006-10-21 GO:0048924 posterior lateral line neuromast mantle cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
2006-10-21 GO:0048920 posterior lateral line neuromast primordium migration Added DEFINITION The migration of a cluster of relatively undifferentiated cells along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
2006-10-21 GO:0048927 posterior lateral line neuromast support cell differentiation Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
2006-10-21 GO:0048915 posterior lateral line system development Added DEFINITION The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
2006-10-21 GO:0014020 primary neural tube formation Updated DEFINITION The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.
2006-10-21 GO:0032357 oxidized purine DNA binding Added DEFINITION Interacting selectively with oxidized purine residues in DNA.
2006-10-21 GO:0032361 pyridoxal phosphate catabolic process Added DEFINITION The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
2006-10-21 GO:0032335 regulation of activin secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell or group of cells.
2006-10-21 GO:0032347 regulation of aldosterone biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
2006-10-21 GO:0032344 regulation of aldosterone metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
2006-10-21 GO:0032374 regulation of cholesterol transport Added DEFINITION Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of, within or between cells.
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