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GO Term History: Displaying 500 audit records for all terms for the date 2006-09-22

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-09-22 GO:0002899 negative regulation of central B cell deletion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.
2006-09-22 GO:0002896 negative regulation of central B cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.
2006-09-22 GO:0002647 negative regulation of central tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.
2006-09-22 GO:0002677 negative regulation of chronic inflammatory response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.
2006-09-22 GO:0002875 negative regulation of chronic inflammatory response to antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002743 negative regulation of cytokine biosynthetic process involved in immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine biosynthesis during immune response.
2006-09-22 GO:0002719 negative regulation of cytokine production involved in immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production during immune response.
2006-09-22 GO:0002740 negative regulation of cytokine secretion involved in immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine secretion during immune response.
2006-09-22 GO:0002605 negative regulation of dendritic cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2006-09-22 GO:0002731 negative regulation of dendritic cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.
2006-09-22 GO:0002267 follicular dendritic cell activation involved in immune response Added DEFINITION A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002268 follicular dendritic cell differentiation Added DEFINITION The process whereby a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.
2006-09-22 GO:0002304 gamma-delta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002290 gamma-delta T cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002303 gamma-delta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002365 gamma-delta T cell lineage commitment Added DEFINITION The process by which a pro-T cell becomes committed to becoming a gamma-delta T cell.
2006-09-22 GO:0002311 gamma-delta T cell proliferation involved in immune response Added DEFINITION The rapid expansion of an gamma-delta T cell population by cell division during an immune response.
2006-09-22 GO:0002206 gene conversion of immunoglobulin genes Added DEFINITION The somatic process by which immunoglobulin genes are diversified through the mechanism of gene conversion.
2006-09-22 GO:0002207 gene conversion of immunoglobulin genes involved in immune response Added DEFINITION The somatic process by which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of an immune response.
2006-09-22 GO:0002314 germinal center B cell differentiation Added DEFINITION The process whereby a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).
2006-09-22 GO:0002467 germinal center formation Added DEFINITION The process by which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
2006-09-22 GO:0043361 glial cell fate determination (sensu Nematoda and Protostomia) Updated DEFINITION Process by which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed. As in, but not restricted to, the roundworms (Nematoda, ncbi_taxonomy_id:6231) and the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).
2006-09-22 GO:0032263 GMP salvage Added DEFINITION Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
2006-09-22 GO:0002432 granuloma formation Added DEFINITION The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.
2006-09-22 GO:0002246 wound healing involved in inflammatory response Added DEFINITION The series of events that restore integrity to damaged tissue during or following an inflammatory response.
2006-09-22 GO:0002244 hematopoietic progenitor cell differentiation Added DEFINITION The process whereby a unspecialized hemopoietic stem cell acquires the specialized features of a hemopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2006-09-22 GO:0002878 negative regulation of acute inflammatory response to non-antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002820 negative regulation of adaptive immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
2006-09-22 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response , as in, but not restricted to, the jawed vertebrates (Gnathostomata, ncbi_taxonomy_id:7776).
2006-09-22 GO:0002809 negative regulation of antibacterial peptide biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.
2006-09-22 GO:0002787 negative regulation of antibacterial peptide production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.
2006-09-22 GO:0002798 negative regulation of antibacterial peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.
2006-09-22 GO:0002811 negative regulation of antifungal peptide biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.
2006-09-22 GO:0002789 negative regulation of antifungal peptide production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.
2006-09-22 GO:0002801 negative regulation of antifungal peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of .
2006-09-22 GO:0002578 negative regulation of antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.
2006-09-22 GO:0002599 negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
2006-09-22 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
2006-09-22 GO:0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
2006-09-22 GO:0002596 negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
2006-09-22 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2006-09-22 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2006-09-22 GO:0002602 negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2006-09-22 GO:0002593 negative regulation of antigen processing and presentation via MHC class Ib Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2006-09-22 GO:0002806 negative regulation of antimicrobial peptide biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2006-09-22 GO:0002785 negative regulation of antimicrobial peptide production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.
2006-09-22 GO:0002795 negative regulation of antimicrobial peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.
2006-09-22 GO:0002671 negative regulation of B cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.
2006-09-22 GO:0002623 negative regulation of B cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.
2006-09-22 GO:0002903 negative regulation of B cell apoptotic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptosis.
2006-09-22 GO:0002722 negative regulation of B cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.
2006-09-22 GO:0002868 negative regulation of B cell deletion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.
2006-09-22 GO:0002713 negative regulation of B cell mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.
2006-09-22 GO:0002662 negative regulation of B cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.
2006-09-22 GO:0002316 follicular B cell differentiation Added DEFINITION The process whereby a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
2006-09-22 GO:0002266 follicular dendritic cell activation Added DEFINITION A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
2006-09-22 GO:0002814 negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-negative bacteria.
2006-09-22 GO:0002817 negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-positive bacteria.
2006-09-22 GO:0002692 negative regulation of cellular extravasation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.
2006-09-22 GO:0032269 negative regulation of cellular protein metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
2006-09-22 GO:0002915 negative regulation of central B cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.
2006-09-22 GO:0002635 negative regulation of germinal center formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.
2006-09-22 GO:0002632 negative regulation of granuloma formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.
2006-09-22 GO:0002921 negative regulation of humoral immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
2006-09-22 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2006-09-22 GO:0002884 negative regulation of hypersensitivity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.
2006-09-22 GO:0002698 negative regulation of immune effector process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.
2006-09-22 GO:0002838 negative regulation of immune response to tumor cell Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.
2006-09-22 GO:0002683 negative regulation of immune system process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
2006-09-22 GO:0002641 negative regulation of immunoglobulin biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin biosynthesis.
2006-09-22 GO:0002890 negative regulation of immunoglobulin mediated immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.
2006-09-22 GO:0002638 negative regulation of immunoglobulin production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.
2006-09-22 GO:0002862 negative regulation of inflammatory response to antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002257 negative regulation of kinin cascade Added DEFINITION Any process that stops, prevents or reduces the frequency, rate, or extent of the kinin cascade.
2006-09-22 GO:0002384 hepatic immune response Added DEFINITION An immune response taking place in the liver.
2006-09-22 GO:0002349 histamine production involved in inflammatory response Added DEFINITION The synthesis or release of histamine following a stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002557 histamine secretion by basophil Added DEFINITION The regulated release of histamine by a basophil or group of basophils.
2006-09-22 GO:0002695 negative regulation of leukocyte activation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.
2006-09-22 GO:0002689 negative regulation of leukocyte chemotaxis Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.
2006-09-22 GO:0002704 negative regulation of leukocyte mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.
2006-09-22 GO:0002686 negative regulation of leukocyte migration Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.
2006-09-22 GO:0002912 negative regulation of lymphocyte anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.
2006-09-22 GO:0002707 negative regulation of lymphocyte mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.
2006-09-22 GO:0002617 negative regulation of macrophage antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.
2006-09-22 GO:0002906 negative regulation of mature B cell apoptotic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptosis.
2006-09-22 GO:0002614 negative regulation of monocyte antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.
2006-09-22 GO:0002608 negative regulation of myeloid dendritic cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002734 negative regulation of myeloid dendritic cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2006-09-22 GO:0002762 negative regulation of myeloid leukocyte differentiation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.
2006-09-22 GO:0002887 negative regulation of myeloid leukocyte mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2006-09-22 GO:0002728 negative regulation of natural killer cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.
2006-09-22 GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2006-09-22 GO:0002856 negative regulation of natural killer cell mediated immune response to tumor cell Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2006-09-22 GO:0002716 negative regulation of natural killer cell mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.
2006-09-22 GO:0002872 negative regulation of natural killer cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.
2006-09-22 GO:0002620 negative regulation of non-professional antigen presenting cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2006-09-22 GO:0002792 negative regulation of peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.
2006-09-22 GO:0002918 negative regulation of peripheral B cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.
2006-09-22 GO:0002909 negative regulation of peripheral B cell deletion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.
2006-09-22 GO:0002850 negative regulation of peripheral T cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.
2006-09-22 GO:0002659 negative regulation of peripheral tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.
2006-09-22 GO:0002549 negative regulation of plasma kallikrein-kinin cascade Added DEFINITION Any process that stops, prevents or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
2006-09-22 GO:0002611 negative regulation of plasmacytoid dendritic cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002737 negative regulation of plasmacytoid dendritic cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2006-09-22 GO:0002701 negative regulation of production of molecular mediator of immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.
2006-09-22 GO:0032272 negative regulation of protein polymerization Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the process of creating protein polymers.
2006-09-22 GO:0002629 negative regulation of proteolysis associated with antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2006-09-22 GO:0002832 negative regulation of response to biotic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
2006-09-22 GO:0002835 negative regulation of response to tumor cell Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.
2006-09-22 GO:0002668 negative regulation of T cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.
2006-09-22 GO:0002626 negative regulation of T cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.
2006-09-22 GO:0002839 positive regulation of immune response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.
2006-09-22 GO:0002684 positive regulation of immune system process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immune system process.
2006-09-22 GO:0002642 positive regulation of immunoglobulin biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of immunoglobulin biosynthesis.
2006-09-22 GO:0002891 positive regulation of immunoglobulin mediated immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
2006-09-22 GO:0002639 positive regulation of immunoglobulin production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.
2006-09-22 GO:0002863 positive regulation of inflammatory response to antigenic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002258 positive regulation of kinin cascade Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the kinin cascade.
2006-09-22 GO:0002696 positive regulation of leukocyte activation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
2006-09-22 GO:0002690 positive regulation of leukocyte chemotaxis Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
2006-09-22 GO:0002705 positive regulation of leukocyte mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.
2006-09-22 GO:0002687 positive regulation of leukocyte migration Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte migration.
2006-09-22 GO:0002913 positive regulation of lymphocyte anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.
2006-09-22 GO:0002708 positive regulation of lymphocyte mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.
2006-09-22 GO:0002282 microglial cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002280 monocyte activation involved in immune response Added DEFINITION The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002471 monocyte antigen processing and presentation Added DEFINITION The process by which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2006-09-22 GO:0002548 monocyte chemotaxis Added DEFINITION The movement of a monocyte in response to an external stimulus.
2006-09-22 GO:0002385 mucosal immune response Added DEFINITION An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.
2006-09-22 GO:0002261 mucosal lymphocyte homeostasis Added DEFINITION The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.
2006-09-22 GO:0002427 mucosal tolerance induction Added DEFINITION Tolerance induction taking place in the mucosal tissues.
2006-09-22 GO:0002755 MyD88-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor and relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2006-09-22 GO:0002756 MyD88-independent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2006-09-22 GO:0002275 myeloid cell activation involved in immune response Added DEFINITION A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002262 myeloid cell homeostasis Added DEFINITION The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
2006-09-22 GO:0002277 myeloid dendritic cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002469 myeloid dendritic cell antigen processing and presentation Added DEFINITION The process by which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2006-09-22 GO:0002408 myeloid dendritic cell chemotaxis Added DEFINITION The movement of a myeloid dendritic cell in response to an external stimulus.
2006-09-22 GO:0002372 myeloid dendritic cell cytokine production Added DEFINITION Any process that contributes to cytokine production by a myeloid dendritic cell.
2006-09-22 GO:0002284 myeloid dendritic cell differentiation involved in immune response Added DEFINITION The process whereby an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell during an immune response.
2006-09-22 GO:0002274 myeloid leukocyte activation Added DEFINITION A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
2006-09-22 GO:0002573 myeloid leukocyte differentiation Added DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.
2006-09-22 GO:0002444 myeloid leukocyte mediated immunity Added DEFINITION Any process involved in the carrying out of an immune response by a myeloid leukocyte.
2006-09-22 GO:0002318 myeloid progenitor cell differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
2006-09-22 GO:0031484 myosin XIV complex Updated DEFINITION A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.
2006-09-22 GO:0002780 antibacterial peptide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide.
2006-09-22 GO:0002778 antibacterial peptide production Added DEFINITION The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
2006-09-22 GO:0002779 antibacterial peptide secretion Added DEFINITION The regulated release of an antibacterial peptide from a cell or group of cells.
2006-09-22 GO:0002783 antifungal peptide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of an antifungal peptide.
2006-09-22 GO:0002781 antifungal peptide production Added DEFINITION The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
2006-09-22 GO:0002782 antifungal peptide secretion Added DEFINITION The regulated release of an antifungal peptide from a cell or group of cells.
2006-09-22 GO:0002750 antigen processing and presentation following macropinocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.
2006-09-22 GO:0002747 antigen processing and presentation following phagocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.
2006-09-22 GO:0002746 antigen processing and presentation following pinocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
2006-09-22 GO:0002751 antigen processing and presentation following receptor mediated endocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.
2006-09-22 GO:0002748 antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).
2006-09-22 GO:0002745 antigen processing and presentation initiated by receptor mediated uptake of antigen Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.
2006-09-22 GO:0002749 antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen Added DEFINITION Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR).
2006-09-22 GO:0002483 antigen processing and presentation of endogenous peptide antigen Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
2006-09-22 GO:0002487 antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.
2006-09-22 GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex Added DEFINITION An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the centre of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.
2006-09-22 GO:0002323 natural killer cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002370 natural killer cell cytokine production Added DEFINITION Any process that contributes to cytokine production by a natural killer cell.
2006-09-22 GO:0002325 natural killer cell differentiation involved in immune response Added DEFINITION The process whereby a nave natural killer cell acquires the specialized features of an effector natural killer T cell during an immune response.
2006-09-22 GO:0002769 natural killer cell inhibitory signaling pathway Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.
2006-09-22 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
2006-09-22 GO:0002423 natural killer cell mediated immune response to tumor cell Added DEFINITION An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.
2006-09-22 GO:0002228 natural killer cell mediated immunity Added DEFINITION The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
2006-09-22 GO:0002321 natural killer cell progenitor differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a natural killer cell progenitor.
2006-09-22 GO:0002324 natural killer cell proliferation involved in immune response Added DEFINITION The rapid expansion of a natural killer cell population by cell division during an immune response.
2006-09-22 GO:0002519 natural killer cell tolerance induction Added DEFINITION Tolerance induction of natural killer cells.
2006-09-22 GO:0002674 negative regulation of acute inflammatory response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.
2006-09-22 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2006-09-22 GO:0002717 positive regulation of natural killer cell mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.
2006-09-22 GO:0002873 positive regulation of natural killer cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.
2006-09-22 GO:0002621 positive regulation of non-professional antigen presenting cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2006-09-22 GO:0002588 positive regulation of antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2006-09-22 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2006-09-22 GO:0002603 positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2006-09-22 GO:0002594 positive regulation of antigen processing and presentation via MHC class Ib Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2006-09-22 GO:0002760 positive regulation of antimicrobial humoral response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.
2006-09-22 GO:0002807 positive regulation of antimicrobial peptide biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2006-09-22 GO:0002225 positive regulation of antimicrobial peptide production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of .
2006-09-22 GO:0002796 positive regulation of antimicrobial peptide secretion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.
2006-09-22 GO:0002230 positive regulation of defense response to virus by host Added DEFINITION Host processes that result in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
2006-09-22 GO:0002672 positive regulation of B cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell anergy.
2006-09-22 GO:0002624 positive regulation of B cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.
2006-09-22 GO:0002904 positive regulation of B cell apoptotic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell apoptosis.
2006-09-22 GO:0002723 positive regulation of B cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.
2006-09-22 GO:0002869 positive regulation of B cell deletion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell deletion.
2006-09-22 GO:0002714 positive regulation of B cell mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.
2006-09-22 GO:0002663 positive regulation of B cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.
2006-09-22 GO:0002693 positive regulation of cellular extravasation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cellular extravasation.
2006-09-22 GO:0032270 positive regulation of cellular protein metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
2006-09-22 GO:0002916 positive regulation of central B cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central B cell anergy.
2006-09-22 GO:0002900 positive regulation of central B cell deletion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central B cell deletion.
2006-09-22 GO:0002897 positive regulation of central B cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.
2006-09-22 GO:0002648 positive regulation of central tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central tolerance induction.
2006-09-22 GO:0002678 positive regulation of chronic inflammatory response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.
2006-09-22 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002744 positive regulation of cytokine biosynthetic process involved in immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cytokine biosynthesis during immune response.
2006-09-22 GO:0002720 positive regulation of cytokine production involved in immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cytokine production during immune response.
2006-09-22 GO:0002741 positive regulation of cytokine secretion involved in immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cytokine secretion during immune response.
2006-09-22 GO:0002606 positive regulation of dendritic cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2006-09-22 GO:0002732 positive regulation of dendritic cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.
2006-09-22 GO:0002636 positive regulation of germinal center formation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of germinal center formation.
2006-09-22 GO:0002633 positive regulation of granuloma formation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of granuloma formation.
2006-09-22 GO:0002922 positive regulation of humoral immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
2006-09-22 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002250 adaptive immune response Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
2006-09-22 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory), as in, but not restricted to, the jawed vertebrates (Gnathostomata, ncbi_taxonomy_id:7776).
2006-09-22 GO:0002459 adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory), as in, but not restricted to, hagfish and lamprays (Myxinidae, ncbi_taxonomy_id:7762, Petromyzontidae, ncbi_taxonomy_id:7746).
2006-09-22 GO:0048847 adenohypophysis formation Updated DEFINITION The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
2006-09-22 GO:0002299 alpha-beta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002287 alpha-beta T cell activation involved in immune response Added DEFINITION The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002293 alpha-beta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002363 alpha-beta T cell lineage commitment Added DEFINITION The process by which a pro-T cell becomes committed to becoming an alpha-beta T cell.
2006-09-22 GO:0002310 alpha-beta T cell proliferation involved in immune response Added DEFINITION The rapid expansion of an alpha-beta T cell population by cell division during an immune response.
2006-09-22 GO:0002564 alternate splicing of immunoglobulin genes Added DEFINITION The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.
2006-09-22 GO:0002500 proteolysis within lysosome associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.
2006-09-22 GO:0002497 proteasomal proteolysis associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by the proteosome complex contributing to antigen processing and presentation.
2006-09-22 GO:0032261 purine nucleotide salvage Added DEFINITION Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.
2006-09-22 GO:0032262 pyrimidine nucleotide salvage Added DEFINITION Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.
2006-09-22 GO:0009317 acetyl-CoA carboxylase complex Updated DEFINITION A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.
2006-09-22 GO:0002543 activation of blood coagulation via clotting cascade Added DEFINITION Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.
2006-09-22 GO:0002253 activation of immune response Added DEFINITION Any process that initiates an immune response.
2006-09-22 GO:0002218 activation of innate immune response Added DEFINITION Any process that initiates an innate immune response.
2006-09-22 GO:0002219 activation of innate immune response (sensu Viridiplantae) Added DEFINITION Any process that initiates an innate immune response as in, but not restricted to, green plants and algae (Viridiplantae, ncbi_taxonomy_id:33090).
2006-09-22 GO:0002541 activation of plasma proteins involved in acute inflammatory response Added DEFINITION Any process activating plasma proteins via proteolysis during an acute inflammatory response.
2006-09-22 GO:0002526 acute inflammatory response Added DEFINITION Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
2006-09-22 GO:0002438 acute inflammatory response to antigenic stimulus Added DEFINITION An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
2006-09-22 GO:0002525 acute inflammatory response to non-antigenic stimulus Added DEFINITION An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.
2006-09-22 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2006-09-22 GO:0002885 positive regulation of hypersensitivity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
2006-09-22 GO:0002699 positive regulation of immune effector process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immune effector process.
2006-09-22 GO:0002577 regulation of antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation.
2006-09-22 GO:0002598 regulation of antigen processing and presentation of lipid antigen via MHC class Ib Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
2006-09-22 GO:0002583 regulation of antigen processing and presentation of peptide antigen Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
2006-09-22 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
2006-09-22 GO:0002595 regulation of antigen processing and presentation of peptide antigen via MHC class Ib Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
2006-09-22 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2006-09-22 GO:0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2006-09-22 GO:0002601 regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2006-09-22 GO:0002592 regulation of antigen processing and presentation via MHC class Ib Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2006-09-22 GO:0002759 regulation of antimicrobial humoral response Added DEFINITION Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.
2006-09-22 GO:0002805 regulation of antimicrobial peptide biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2006-09-22 GO:0002793 positive regulation of peptide secretion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peptide secretion.
2006-09-22 GO:0002919 positive regulation of peripheral B cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.
2006-09-22 GO:0002910 positive regulation of peripheral B cell deletion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.
2006-09-22 GO:0002851 positive regulation of peripheral T cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.
2006-09-22 GO:0002660 positive regulation of peripheral tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.
2006-09-22 GO:0002550 positive regulation of plasma kallikrein-kinin cascade Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
2006-09-22 GO:0002612 positive regulation of plasmacytoid dendritic cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002738 positive regulation of plasmacytoid dendritic cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2006-09-22 GO:0002702 positive regulation of production of molecular mediator of immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.
2006-09-22 GO:0032273 positive regulation of protein polymerization Added DEFINITION Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.
2006-09-22 GO:0002630 positive regulation of proteolysis associated with antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2006-09-22 GO:0002833 positive regulation of response to biotic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
2006-09-22 GO:0002836 positive regulation of response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.
2006-09-22 GO:0002669 positive regulation of T cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell anergy.
2006-09-22 GO:0002627 positive regulation of T cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.
2006-09-22 GO:0002726 positive regulation of T cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.
2006-09-22 GO:0002854 positive regulation of T cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
2006-09-22 GO:0002842 positive regulation of T cell mediated immune response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
2006-09-22 GO:0002711 positive regulation of T cell mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.
2006-09-22 GO:0002666 positive regulation of T cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.
2006-09-22 GO:0002848 positive regulation of T cell tolerance induction to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.
2006-09-22 GO:0002827 positive regulation of T-helper 1 type immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.
2006-09-22 GO:0002830 positive regulation of type 2 immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a T-helper 2 type immune response.
2006-09-22 GO:0002547 positive regulation of tissue kallikrein-kinin cascade Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
2006-09-22 GO:0002645 positive regulation of tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction.
2006-09-22 GO:0002654 positive regulation of tolerance induction dependent upon immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.
2006-09-22 GO:0002657 positive regulation of tolerance induction to nonself antigen Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.
2006-09-22 GO:0002651 positive regulation of tolerance induction to self antigen Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.
2006-09-22 GO:0002845 positive regulation of tolerance induction to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.
2006-09-22 GO:0002894 positive regulation of type II hypersensitivity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.
2006-09-22 GO:0002331 pre-B cell allelic exclusion Added DEFINITION Expression of a single heavy chain allele during pre-B cell differentiation.
2006-09-22 GO:0002329 pre-B cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
2006-09-22 GO:0002412 antigen transcytosis by M cells in mucosal-associated lymphoid tissue Added DEFINITION The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.
2006-09-22 GO:0002777 antimicrobial peptide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2006-09-22 GO:0002775 antimicrobial peptide production Added DEFINITION The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2006-09-22 GO:0002776 antimicrobial peptide secretion Added DEFINITION The regulated release of an antimicrobial peptide from a cell or group of cells. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2006-09-22 GO:0002265 astrocyte activation involved in immune response Added DEFINITION A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002312 B cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2006-09-22 GO:0002344 B cell affinity maturation Added DEFINITION The process by which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.
2006-09-22 GO:0002515 B cell anergy Added DEFINITION Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
2006-09-22 GO:0002450 B cell antigen processing and presentation Added DEFINITION The process by which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2006-09-22 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
2006-09-22 GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
2006-09-22 GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.
2006-09-22 GO:0002618 positive regulation of macrophage antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.
2006-09-22 GO:0002907 positive regulation of mature B cell apoptotic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of mature B cell apoptosis.
2006-09-22 GO:0002615 positive regulation of monocyte antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.
2006-09-22 GO:0002609 positive regulation of myeloid dendritic cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002735 positive regulation of myeloid dendritic cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2006-09-22 GO:0002763 positive regulation of myeloid leukocyte differentiation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
2006-09-22 GO:0002888 positive regulation of myeloid leukocyte mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2006-09-22 GO:0002729 positive regulation of natural killer cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
2006-09-22 GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2006-09-22 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
2006-09-22 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.
2006-09-22 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002482 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
2006-09-22 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.
2006-09-22 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses an peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
2006-09-22 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.
2006-09-22 GO:0002505 antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.
2006-09-22 GO:0002475 antigen processing and presentation via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
2006-09-22 GO:0002405 antigen sampling by dendritic cells in mucosal-associated lymphoid tissue Added DEFINITION The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.
2006-09-22 GO:0002406 antigen sampling by M cells in mucosal-associated lymphoid tissue Added DEFINITION The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.
2006-09-22 GO:0002404 antigen sampling in mucosal-associated lymphoid tissue Added DEFINITION The process initiating the mucosal immune response which entails the apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.
2006-09-22 GO:0002330 pre-B cell receptor expression Added DEFINITION The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, including expression of the surrogate light chain, association of the surrogate light chain with heavy chain, and expression of the complete pre-B cell receptor on the cell surface.
2006-09-22 GO:0002328 pro-B cell differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
2006-09-22 GO:0002572 pro-T cell differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
2006-09-22 GO:0002680 pro-T cell lineage commitment Added DEFINITION The process by which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.
2006-09-22 GO:0002538 arachidonic acid metabolite production involved in inflammatory response Added DEFINITION The synthesis or release of products of arachidonic acid metabolism following a stimulus during an acute inflammatory response, resulting in an increase in their intracellular or extracellular levels.
2006-09-22 GO:0002393 lysosomal enzyme production involved in inflammatory response Added DEFINITION The synthesis or release of lysosomal enzymes following a stimulus during an acute inflammatory response, resulting in an increase in intracellular or extracellular levels.
2006-09-22 GO:0002532 production of molecular mediator involved in inflammatory response Added DEFINITION The synthesis or release of any molecular mediator of the acute inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002440 production of molecular mediator of immune response Added DEFINITION The synthesis or release of any molecular mediator of the immune response following an immunological stimulus, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002537 nitric oxide production involved in inflammatory response Added DEFINITION The synthesis or release of nitric oxide following a stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002539 prostaglandin production involved in inflammatory response Added DEFINITION The synthesis or release of any prostaglandin following a stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002496 proteolysis associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.
2006-09-22 GO:0002203 proteolysis by cytosolic proteases associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.
2006-09-22 GO:0002498 proteolysis within endoplasmic reticulum associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.
2006-09-22 GO:0002499 proteolysis within endosome associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.
2006-09-22 GO:0002530 regulation of systemic arterial blood pressure involved in acute-phase response Added DEFINITION Any process that modulates the force with which blood travels through the circulatory system during the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
2006-09-22 GO:0002691 regulation of cellular extravasation Added DEFINITION Any process that modulates the frequency, rate, or extent of cellular extravasation.
2006-09-22 GO:0032268 regulation of cellular protein metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
2006-09-22 GO:0002914 regulation of central B cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of central B cell anergy.
2006-09-22 GO:0002898 regulation of central B cell deletion Added DEFINITION Any process that modulates the frequency, rate, or extent of central B cell deletion.
2006-09-22 GO:0002895 regulation of central B cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.
2006-09-22 GO:0002646 regulation of central tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of central tolerance induction.
2006-09-22 GO:0002676 regulation of chronic inflammatory response Added DEFINITION Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.
2006-09-22 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002880 regulation of chronic inflammatory response to non-antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002742 regulation of cytokine biosynthetic process involved in immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of cytokine biosynthesis during immune response.
2006-09-22 GO:0002718 regulation of cytokine production involved in immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of cytokine production during immune response.
2006-09-22 GO:0002739 regulation of cytokine secretion involved in immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of cytokine secretion during immune response.
2006-09-22 GO:0002604 regulation of dendritic cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2006-09-22 GO:0002730 regulation of dendritic cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.
2006-09-22 GO:0002634 regulation of germinal center formation Added DEFINITION Any process that modulates the frequency, rate, or extent of germinal center formation.
2006-09-22 GO:0002631 regulation of granuloma formation Added DEFINITION Any process that modulates the frequency, rate, or extent of granuloma formation.
2006-09-22 GO:0002531 regulation of heart contraction involved in acute-phase response Added DEFINITION Any process that modulates the frequency, rate or extent of heart contraction during the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
2006-09-22 GO:0002920 regulation of humoral immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of a humoral immune response.
2006-09-22 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin Added DEFINITION Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2006-09-22 GO:0002883 regulation of hypersensitivity Added DEFINITION Any process that modulates the frequency, rate, or extent of hypersensitivity.
2006-09-22 GO:0002697 regulation of immune effector process Added DEFINITION Any process that modulates the frequency, rate, or extent of an immune effector process.
2006-09-22 GO:0002837 regulation of immune response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.
2006-09-22 GO:0002682 regulation of immune system process Added DEFINITION Any process that modulates the frequency, rate, or extent of an immune system process.
2006-09-22 GO:0010138 pyrimidine ribonucleotide salvage Updated DEFINITION The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.
2006-09-22 GO:0002673 regulation of acute inflammatory response Added DEFINITION Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
2006-09-22 GO:0002864 regulation of acute inflammatory response to antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002819 regulation of adaptive immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of an adaptive immune response.
2006-09-22 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Added DEFINITION Any process that modulates the frequency, rate, or extent of an adaptive immune response, as in, but not restricted to, the jawed vertebrates (Gnathostomata, ncbi_taxonomy_id:7776).
2006-09-22 GO:0002808 regulation of antibacterial peptide biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.
2006-09-22 GO:0002786 regulation of antibacterial peptide production Added DEFINITION Any process that modulates the frequency, rate, or extent of antibacterial peptide production.
2006-09-22 GO:0002797 regulation of antibacterial peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.
2006-09-22 GO:0002810 regulation of antifungal peptide biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.
2006-09-22 GO:0002788 regulation of antifungal peptide production Added DEFINITION Any process that modulates the frequency, rate, or extent of antifungal peptide production.
2006-09-22 GO:0002800 regulation of antifungal peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of .
2006-09-22 GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment Added DEFINITION The process by which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2006-09-22 GO:0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
2006-09-22 GO:0002352 B cell negative selection Added DEFINITION Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.
2006-09-22 GO:0002346 B cell positive selection Added DEFINITION Any process by which B cells are selected to survive based on signaling through the B cell antigen receptor.
2006-09-22 GO:0002322 B cell proliferation involved in immune response Added DEFINITION The rapid expansion of a B cell population by cell division following B cell activation during an immune response.
2006-09-22 GO:0002452 B cell receptor editing Added DEFINITION The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.
2006-09-22 GO:0002339 B cell selection Added DEFINITION The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.
2006-09-22 GO:0002514 B cell tolerance induction Added DEFINITION A process involving any mechanism for tolerance induction in B cells.
2006-09-22 GO:0002402 B cell tolerance induction in mucosal-associated lymphoid tissue Added DEFINITION Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.
2006-09-22 GO:0002336 B-1 B cell lineage commitment Added DEFINITION The process by which an immature B cell becomes committed to become a B-1 B cell.
2006-09-22 GO:0002359 B-1 B cell proliferation Added DEFINITION The rapid expansion of a B-1 B cell by cell division. Follows B cell activation.
2006-09-22 GO:0002337 B-1a B cell differentiation Added DEFINITION The process whereby B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.
2006-09-22 GO:0002338 B-1b B cell differentiation Added DEFINITION The process whereby B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
2006-09-22 GO:0002276 basophil activation involved in immune response Added DEFINITION A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002575 basophil chemotaxis Added DEFINITION The movement of a basophil in response to an external stimulus.
2006-09-22 GO:0002561 basophil degranulation Added DEFINITION The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.
2006-09-22 GO:0002560 basophil mediated immunity Added DEFINITION Any process involved in the carrying out of an immune response by a mast cell.
2006-09-22 GO:0002209 behavioral defense response Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat to that organism.
2006-09-22 GO:0002211 behavioral defense response to insect Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.
2006-09-22 GO:0002212 behavioral defense response to nematode Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.
2006-09-22 GO:0002210 behavioral response to wounding Added DEFINITION A behavioral response resulting from wounding.
2006-09-22 GO:0002812 biosynthetic process of antibacterial peptides active against Gram-negative bacteria Added DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.
2006-09-22 GO:0002815 biosynthetic process of antibacterial peptides active against Gram-positive bacteria Added DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.
2006-09-22 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning Updated DEFINITION A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.
2006-09-22 GO:0002784 regulation of antimicrobial peptide production Added DEFINITION Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.
2006-09-22 GO:0002794 regulation of antimicrobial peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.
2006-09-22 GO:0002670 regulation of B cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell anergy.
2006-09-22 GO:0002622 regulation of B cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.
2006-09-22 GO:0002902 regulation of B cell apoptotic process Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell apoptosis.
2006-09-22 GO:0002721 regulation of B cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell cytokine production.
2006-09-22 GO:0002867 regulation of B cell deletion Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell deletion.
2006-09-22 GO:0002712 regulation of B cell mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
2006-09-22 GO:0002661 regulation of B cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell tolerance induction.
2006-09-22 GO:0002813 regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Added DEFINITION Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-negative bacteria.
2006-09-22 GO:0002816 regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Added DEFINITION Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-positive bacteria.
2006-09-22 GO:0002761 regulation of myeloid leukocyte differentiation Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.
2006-09-22 GO:0002886 regulation of myeloid leukocyte mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2006-09-22 GO:0002727 regulation of natural killer cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.
2006-09-22 GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2006-09-22 GO:0002855 regulation of natural killer cell mediated immune response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2006-09-22 GO:0002715 regulation of natural killer cell mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.
2006-09-22 GO:0002871 regulation of natural killer cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.
2006-09-22 GO:0002619 regulation of non-professional antigen presenting cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2006-09-22 GO:0002791 regulation of peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of peptide secretion.
2006-09-22 GO:0002917 regulation of peripheral B cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.
2006-09-22 GO:0002908 regulation of peripheral B cell deletion Added DEFINITION Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.
2006-09-22 GO:0002849 regulation of peripheral T cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.
2006-09-22 GO:0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002307 CD8-positive, alpha-beta regulatory T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.
2006-09-22 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002263 cell activation involved in immune response Added DEFINITION A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002421 B cell antigen processing and presentation following pinocytosis Added DEFINITION B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
2006-09-22 GO:0002417 B cell antigen processing and presentation mediated by B cell receptor uptake of antigen Added DEFINITION B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.
2006-09-22 GO:0002368 B cell cytokine production Added DEFINITION Any process that contributes to cytokine production by a B cell.
2006-09-22 GO:0002516 B cell deletion Added DEFINITION The apoptotic death of B cells which is part of B cell tolerance induction.
2006-09-22 GO:0002358 B cell homeostatic proliferation Added DEFINITION The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.
2006-09-22 GO:0002773 B cell inhibitory signaling pathway Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.
2006-09-22 GO:0002326 B cell lineage commitment Added DEFINITION The process whereby a lymphoid progenitor cell becomes committed to become any type of B cell.
2006-09-22 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002490 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002491 antigen processing and presentation of endogenous peptide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses an peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
2006-09-22 GO:0002478 antigen processing and presentation of exogenous peptide antigen Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.
2006-09-22 GO:0032166 chlamydospore septin filament array Updated DEFINITION Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.
2006-09-22 GO:0002544 chronic inflammatory response Added DEFINITION Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.
2006-09-22 GO:0002703 regulation of leukocyte mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
2006-09-22 GO:0002685 regulation of leukocyte migration Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte migration.
2006-09-22 GO:0002911 regulation of lymphocyte anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of lymphocyte anergy.
2006-09-22 GO:0002706 regulation of lymphocyte mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
2006-09-22 GO:0002616 regulation of macrophage antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.
2006-09-22 GO:0002905 regulation of mature B cell apoptotic process Added DEFINITION Any process that modulates the frequency, rate, or extent of mature B cell apoptosis.
2006-09-22 GO:0002613 regulation of monocyte antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.
2006-09-22 GO:0002607 regulation of myeloid dendritic cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002733 regulation of myeloid dendritic cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2006-09-22 GO:0002736 regulation of plasmacytoid dendritic cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2006-09-22 GO:0002700 regulation of production of molecular mediator of immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.
2006-09-22 GO:0032271 regulation of protein polymerization Added DEFINITION Any process that modulates the frequency, rate or extent of the process of creating protein polymers.
2006-09-22 GO:0002628 regulation of proteolysis associated with antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2006-09-22 GO:0002831 regulation of response to biotic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
2006-09-22 GO:0002834 regulation of response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of a response to tumor cell.
2006-09-22 GO:0002667 regulation of T cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell anergy.
2006-09-22 GO:0002625 regulation of T cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.
2006-09-22 GO:0002724 regulation of T cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell cytokine production.
2006-09-22 GO:0002852 regulation of T cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
2006-09-22 GO:0002840 regulation of T cell mediated immune response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
2006-09-22 GO:0002709 regulation of T cell mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell mediated immunity.
2006-09-22 GO:0002664 regulation of T cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell tolerance induction.
2006-09-22 GO:0002846 regulation of T cell tolerance induction to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.
2006-09-22 GO:0002825 regulation of T-helper 1 type immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.
2006-09-22 GO:0002828 regulation of type 2 immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of a T-helper 2 type immune response.
2006-09-22 GO:0002382 regulation of tissue kallikrein-kinin cascade Added DEFINITION Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
2006-09-22 GO:0002643 regulation of tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction.
2006-09-22 GO:0002652 regulation of tolerance induction dependent upon immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.
2006-09-22 GO:0002655 regulation of tolerance induction to nonself antigen Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.
2006-09-22 GO:0002649 regulation of tolerance induction to self antigen Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.
2006-09-22 GO:0002843 regulation of tolerance induction to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.
2006-09-22 GO:0002892 regulation of type II hypersensitivity Added DEFINITION Any process that modulates the frequency, rate, or extent of type II hypersensitivity.
2006-09-22 GO:0002528 regulation of vascular permeability involved in acute inflammatory response Added DEFINITION Any process that modulates the extent to which blood vessels can be pervaded by fluid during an acute inflammatory response.
2006-09-22 GO:0002536 respiratory burst involved in inflammatory response Added DEFINITION A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus during an acute inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.
2006-09-22 GO:0002679 respiratory burst involved in defense response Added DEFINITION A phase of elevated metabolic activity, during which oxygen consumption increases made as a defense reponse ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
2006-09-22 GO:0002237 response to molecule of bacterial origin Added DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of bacterial associated molecules such as peptides derived from bacterial flagellin.
2006-09-22 GO:0002238 response to molecule of fungal origin Added DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of fungal associated molecules such as chito-octomer oligosaccharide.
2006-09-22 GO:0032260 response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.
2006-09-22 GO:0002239 response to oomycetes Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.
2006-09-22 GO:0002439 chronic inflammatory response to antigenic stimulus Added DEFINITION A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.
2006-09-22 GO:0002545 chronic inflammatory response to non-antigenic stimulus Added DEFINITION A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.
2006-09-22 GO:0002247 clearance of damaged tissue involved in inflammatory response wound healing Added DEFINITION The series of events leading to removal of necrotic debris during or following an inflammatory response.
2006-09-22 GO:0002430 complement receptor mediated signaling pathway Added DEFINITION A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.
2006-09-22 GO:0002248 connective tissue replacement involved in inflammatory response wound healing Added DEFINITION The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared during or following an inflammatory response.
2006-09-22 GO:0002375 cytokine biosynthetic process involved in immune response Added DEFINITION The chemical reactions and pathways resulting in the formation of a cytokine during an immune response.
2006-09-22 GO:0002534 cytokine production involved in inflammatory response Added DEFINITION The synthesis or release of a cytokine following a inflammatory stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002367 cytokine production involved in immune response Added DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002374 cytokine secretion involved in immune response Added DEFINITION The regulated release of cytokines from a cell or group of cells during an immune response.
2006-09-22 GO:0002200 somatic diversification of immune receptors Added DEFINITION The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
2006-09-22 GO:0002569 somatic diversification of immune receptors by N region addition Added DEFINITION The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.
2006-09-22 GO:0002640 regulation of immunoglobulin biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of immunoglobulin biosynthesis.
2006-09-22 GO:0002889 regulation of immunoglobulin mediated immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
2006-09-22 GO:0002637 regulation of immunoglobulin production Added DEFINITION Any process that modulates the frequency, rate, or extent of immunoglobulin production.
2006-09-22 GO:0002861 regulation of inflammatory response to antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002256 regulation of kinin cascade Added DEFINITION Any process that modulates the frequency, rate, or extent of the kinin cascade.
2006-09-22 GO:0002694 regulation of leukocyte activation Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte activation.
2006-09-22 GO:0002688 regulation of leukocyte chemotaxis Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.
2006-09-22 GO:0002306 CD4-positive gamma-delta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002301 CD4-positive, alpha-beta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2006-09-22 GO:0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an CD4-positive, CD25-positive, alpha-beta regulatory T cell during an immune response.
2006-09-22 GO:0002774 Fc receptor mediated inhibitory signaling pathway Added DEFINITION A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
2006-09-22 GO:0002431 Fc receptor mediated stimulatory signaling pathway Added DEFINITION A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
2006-09-22 GO:0048810 female analia morphogenesis Updated DEFINITION The process by which the anatomical structures of the analia of the female are generated and organized. Morphogenesis pertains to the creation of form. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2006-09-22 GO:0002553 histamine secretion by mast cell Added DEFINITION The regulated release of histamine by a mast cell or group of mast cells.
2006-09-22 GO:0002555 histamine secretion by platelet Added DEFINITION The regulated release of histamine by a platelet or group of platelets.
2006-09-22 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a cytoplasmic pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-09-22 GO:0002899 negative regulation of central B cell deletion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.
2006-09-22 GO:0002896 negative regulation of central B cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.
2006-09-22 GO:0002647 negative regulation of central tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.
2006-09-22 GO:0002677 negative regulation of chronic inflammatory response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.
2006-09-22 GO:0002875 negative regulation of chronic inflammatory response to antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002743 negative regulation of cytokine biosynthetic process involved in immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine biosynthesis during immune response.
2006-09-22 GO:0002719 negative regulation of cytokine production involved in immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production during immune response.
2006-09-22 GO:0002740 negative regulation of cytokine secretion involved in immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine secretion during immune response.
2006-09-22 GO:0002605 negative regulation of dendritic cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2006-09-22 GO:0002731 negative regulation of dendritic cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.
2006-09-22 GO:0002267 follicular dendritic cell activation involved in immune response Added DEFINITION A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002268 follicular dendritic cell differentiation Added DEFINITION The process whereby a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.
2006-09-22 GO:0002304 gamma-delta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002290 gamma-delta T cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002303 gamma-delta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002365 gamma-delta T cell lineage commitment Added DEFINITION The process by which a pro-T cell becomes committed to becoming a gamma-delta T cell.
2006-09-22 GO:0002311 gamma-delta T cell proliferation involved in immune response Added DEFINITION The rapid expansion of an gamma-delta T cell population by cell division during an immune response.
2006-09-22 GO:0002206 gene conversion of immunoglobulin genes Added DEFINITION The somatic process by which immunoglobulin genes are diversified through the mechanism of gene conversion.
2006-09-22 GO:0002207 gene conversion of immunoglobulin genes involved in immune response Added DEFINITION The somatic process by which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of an immune response.
2006-09-22 GO:0002314 germinal center B cell differentiation Added DEFINITION The process whereby a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).
2006-09-22 GO:0002467 germinal center formation Added DEFINITION The process by which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
2006-09-22 GO:0043361 glial cell fate determination (sensu Nematoda and Protostomia) Updated DEFINITION Process by which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed. As in, but not restricted to, the roundworms (Nematoda, ncbi_taxonomy_id:6231) and the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).
2006-09-22 GO:0032263 GMP salvage Added DEFINITION Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
2006-09-22 GO:0002432 granuloma formation Added DEFINITION The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.
2006-09-22 GO:0002246 wound healing involved in inflammatory response Added DEFINITION The series of events that restore integrity to damaged tissue during or following an inflammatory response.
2006-09-22 GO:0002244 hematopoietic progenitor cell differentiation Added DEFINITION The process whereby a unspecialized hemopoietic stem cell acquires the specialized features of a hemopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2006-09-22 GO:0002878 negative regulation of acute inflammatory response to non-antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002820 negative regulation of adaptive immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
2006-09-22 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response , as in, but not restricted to, the jawed vertebrates (Gnathostomata, ncbi_taxonomy_id:7776).
2006-09-22 GO:0002809 negative regulation of antibacterial peptide biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.
2006-09-22 GO:0002787 negative regulation of antibacterial peptide production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.
2006-09-22 GO:0002798 negative regulation of antibacterial peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.
2006-09-22 GO:0002811 negative regulation of antifungal peptide biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.
2006-09-22 GO:0002789 negative regulation of antifungal peptide production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.
2006-09-22 GO:0002801 negative regulation of antifungal peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of .
2006-09-22 GO:0002578 negative regulation of antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.
2006-09-22 GO:0002599 negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
2006-09-22 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
2006-09-22 GO:0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
2006-09-22 GO:0002596 negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
2006-09-22 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2006-09-22 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2006-09-22 GO:0002602 negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2006-09-22 GO:0002593 negative regulation of antigen processing and presentation via MHC class Ib Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2006-09-22 GO:0002806 negative regulation of antimicrobial peptide biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2006-09-22 GO:0002785 negative regulation of antimicrobial peptide production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.
2006-09-22 GO:0002795 negative regulation of antimicrobial peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.
2006-09-22 GO:0002671 negative regulation of B cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.
2006-09-22 GO:0002623 negative regulation of B cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.
2006-09-22 GO:0002903 negative regulation of B cell apoptotic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptosis.
2006-09-22 GO:0002722 negative regulation of B cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.
2006-09-22 GO:0002868 negative regulation of B cell deletion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.
2006-09-22 GO:0002713 negative regulation of B cell mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.
2006-09-22 GO:0002662 negative regulation of B cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.
2006-09-22 GO:0002316 follicular B cell differentiation Added DEFINITION The process whereby a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
2006-09-22 GO:0002266 follicular dendritic cell activation Added DEFINITION A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
2006-09-22 GO:0002814 negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-negative bacteria.
2006-09-22 GO:0002817 negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-positive bacteria.
2006-09-22 GO:0002692 negative regulation of cellular extravasation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.
2006-09-22 GO:0032269 negative regulation of cellular protein metabolic process Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
2006-09-22 GO:0002915 negative regulation of central B cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.
2006-09-22 GO:0002635 negative regulation of germinal center formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.
2006-09-22 GO:0002632 negative regulation of granuloma formation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.
2006-09-22 GO:0002921 negative regulation of humoral immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
2006-09-22 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2006-09-22 GO:0002884 negative regulation of hypersensitivity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.
2006-09-22 GO:0002698 negative regulation of immune effector process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.
2006-09-22 GO:0002838 negative regulation of immune response to tumor cell Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.
2006-09-22 GO:0002683 negative regulation of immune system process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
2006-09-22 GO:0002641 negative regulation of immunoglobulin biosynthetic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin biosynthesis.
2006-09-22 GO:0002890 negative regulation of immunoglobulin mediated immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.
2006-09-22 GO:0002638 negative regulation of immunoglobulin production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.
2006-09-22 GO:0002862 negative regulation of inflammatory response to antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002257 negative regulation of kinin cascade Added DEFINITION Any process that stops, prevents or reduces the frequency, rate, or extent of the kinin cascade.
2006-09-22 GO:0002384 hepatic immune response Added DEFINITION An immune response taking place in the liver.
2006-09-22 GO:0002349 histamine production involved in inflammatory response Added DEFINITION The synthesis or release of histamine following a stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002557 histamine secretion by basophil Added DEFINITION The regulated release of histamine by a basophil or group of basophils.
2006-09-22 GO:0002695 negative regulation of leukocyte activation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.
2006-09-22 GO:0002689 negative regulation of leukocyte chemotaxis Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.
2006-09-22 GO:0002704 negative regulation of leukocyte mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.
2006-09-22 GO:0002686 negative regulation of leukocyte migration Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.
2006-09-22 GO:0002912 negative regulation of lymphocyte anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.
2006-09-22 GO:0002707 negative regulation of lymphocyte mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.
2006-09-22 GO:0002617 negative regulation of macrophage antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.
2006-09-22 GO:0002906 negative regulation of mature B cell apoptotic process Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptosis.
2006-09-22 GO:0002614 negative regulation of monocyte antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.
2006-09-22 GO:0002608 negative regulation of myeloid dendritic cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002734 negative regulation of myeloid dendritic cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2006-09-22 GO:0002762 negative regulation of myeloid leukocyte differentiation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.
2006-09-22 GO:0002887 negative regulation of myeloid leukocyte mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2006-09-22 GO:0002728 negative regulation of natural killer cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.
2006-09-22 GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2006-09-22 GO:0002856 negative regulation of natural killer cell mediated immune response to tumor cell Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2006-09-22 GO:0002716 negative regulation of natural killer cell mediated immunity Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.
2006-09-22 GO:0002872 negative regulation of natural killer cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.
2006-09-22 GO:0002620 negative regulation of non-professional antigen presenting cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2006-09-22 GO:0002792 negative regulation of peptide secretion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.
2006-09-22 GO:0002918 negative regulation of peripheral B cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.
2006-09-22 GO:0002909 negative regulation of peripheral B cell deletion Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.
2006-09-22 GO:0002850 negative regulation of peripheral T cell tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.
2006-09-22 GO:0002659 negative regulation of peripheral tolerance induction Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.
2006-09-22 GO:0002549 negative regulation of plasma kallikrein-kinin cascade Added DEFINITION Any process that stops, prevents or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
2006-09-22 GO:0002611 negative regulation of plasmacytoid dendritic cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002737 negative regulation of plasmacytoid dendritic cell cytokine production Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2006-09-22 GO:0002701 negative regulation of production of molecular mediator of immune response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.
2006-09-22 GO:0032272 negative regulation of protein polymerization Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the process of creating protein polymers.
2006-09-22 GO:0002629 negative regulation of proteolysis associated with antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2006-09-22 GO:0002832 negative regulation of response to biotic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
2006-09-22 GO:0002835 negative regulation of response to tumor cell Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.
2006-09-22 GO:0002668 negative regulation of T cell anergy Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.
2006-09-22 GO:0002626 negative regulation of T cell antigen processing and presentation Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.
2006-09-22 GO:0002839 positive regulation of immune response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.
2006-09-22 GO:0002684 positive regulation of immune system process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immune system process.
2006-09-22 GO:0002642 positive regulation of immunoglobulin biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of immunoglobulin biosynthesis.
2006-09-22 GO:0002891 positive regulation of immunoglobulin mediated immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
2006-09-22 GO:0002639 positive regulation of immunoglobulin production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.
2006-09-22 GO:0002863 positive regulation of inflammatory response to antigenic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002258 positive regulation of kinin cascade Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the kinin cascade.
2006-09-22 GO:0002696 positive regulation of leukocyte activation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
2006-09-22 GO:0002690 positive regulation of leukocyte chemotaxis Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
2006-09-22 GO:0002705 positive regulation of leukocyte mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.
2006-09-22 GO:0002687 positive regulation of leukocyte migration Added DEFINITION Any process that activates or increases the frequency, rate, or extent of leukocyte migration.
2006-09-22 GO:0002913 positive regulation of lymphocyte anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.
2006-09-22 GO:0002708 positive regulation of lymphocyte mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.
2006-09-22 GO:0002282 microglial cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002280 monocyte activation involved in immune response Added DEFINITION The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002471 monocyte antigen processing and presentation Added DEFINITION The process by which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2006-09-22 GO:0002548 monocyte chemotaxis Added DEFINITION The movement of a monocyte in response to an external stimulus.
2006-09-22 GO:0002385 mucosal immune response Added DEFINITION An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.
2006-09-22 GO:0002261 mucosal lymphocyte homeostasis Added DEFINITION The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.
2006-09-22 GO:0002427 mucosal tolerance induction Added DEFINITION Tolerance induction taking place in the mucosal tissues.
2006-09-22 GO:0002755 MyD88-dependent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor and relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2006-09-22 GO:0002756 MyD88-independent toll-like receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2006-09-22 GO:0002275 myeloid cell activation involved in immune response Added DEFINITION A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002262 myeloid cell homeostasis Added DEFINITION The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
2006-09-22 GO:0002277 myeloid dendritic cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002469 myeloid dendritic cell antigen processing and presentation Added DEFINITION The process by which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2006-09-22 GO:0002408 myeloid dendritic cell chemotaxis Added DEFINITION The movement of a myeloid dendritic cell in response to an external stimulus.
2006-09-22 GO:0002372 myeloid dendritic cell cytokine production Added DEFINITION Any process that contributes to cytokine production by a myeloid dendritic cell.
2006-09-22 GO:0002284 myeloid dendritic cell differentiation involved in immune response Added DEFINITION The process whereby an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell during an immune response.
2006-09-22 GO:0002274 myeloid leukocyte activation Added DEFINITION A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
2006-09-22 GO:0002573 myeloid leukocyte differentiation Added DEFINITION The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.
2006-09-22 GO:0002444 myeloid leukocyte mediated immunity Added DEFINITION Any process involved in the carrying out of an immune response by a myeloid leukocyte.
2006-09-22 GO:0002318 myeloid progenitor cell differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
2006-09-22 GO:0031484 myosin XIV complex Updated DEFINITION A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.
2006-09-22 GO:0002780 antibacterial peptide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide.
2006-09-22 GO:0002778 antibacterial peptide production Added DEFINITION The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
2006-09-22 GO:0002779 antibacterial peptide secretion Added DEFINITION The regulated release of an antibacterial peptide from a cell or group of cells.
2006-09-22 GO:0002783 antifungal peptide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of an antifungal peptide.
2006-09-22 GO:0002781 antifungal peptide production Added DEFINITION The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
2006-09-22 GO:0002782 antifungal peptide secretion Added DEFINITION The regulated release of an antifungal peptide from a cell or group of cells.
2006-09-22 GO:0002750 antigen processing and presentation following macropinocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.
2006-09-22 GO:0002747 antigen processing and presentation following phagocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.
2006-09-22 GO:0002746 antigen processing and presentation following pinocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
2006-09-22 GO:0002751 antigen processing and presentation following receptor mediated endocytosis Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.
2006-09-22 GO:0002748 antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).
2006-09-22 GO:0002745 antigen processing and presentation initiated by receptor mediated uptake of antigen Added DEFINITION Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.
2006-09-22 GO:0002749 antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen Added DEFINITION Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR).
2006-09-22 GO:0002483 antigen processing and presentation of endogenous peptide antigen Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
2006-09-22 GO:0002487 antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.
2006-09-22 GO:0017146 N-methyl-D-aspartate selective glutamate receptor complex Added DEFINITION An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the centre of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.
2006-09-22 GO:0002323 natural killer cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002370 natural killer cell cytokine production Added DEFINITION Any process that contributes to cytokine production by a natural killer cell.
2006-09-22 GO:0002325 natural killer cell differentiation involved in immune response Added DEFINITION The process whereby a nave natural killer cell acquires the specialized features of an effector natural killer T cell during an immune response.
2006-09-22 GO:0002769 natural killer cell inhibitory signaling pathway Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.
2006-09-22 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
2006-09-22 GO:0002423 natural killer cell mediated immune response to tumor cell Added DEFINITION An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.
2006-09-22 GO:0002228 natural killer cell mediated immunity Added DEFINITION The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
2006-09-22 GO:0002321 natural killer cell progenitor differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a natural killer cell progenitor.
2006-09-22 GO:0002324 natural killer cell proliferation involved in immune response Added DEFINITION The rapid expansion of a natural killer cell population by cell division during an immune response.
2006-09-22 GO:0002519 natural killer cell tolerance induction Added DEFINITION Tolerance induction of natural killer cells.
2006-09-22 GO:0002674 negative regulation of acute inflammatory response Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.
2006-09-22 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2006-09-22 GO:0002717 positive regulation of natural killer cell mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.
2006-09-22 GO:0002873 positive regulation of natural killer cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.
2006-09-22 GO:0002621 positive regulation of non-professional antigen presenting cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2006-09-22 GO:0002588 positive regulation of antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2006-09-22 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2006-09-22 GO:0002603 positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2006-09-22 GO:0002594 positive regulation of antigen processing and presentation via MHC class Ib Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2006-09-22 GO:0002760 positive regulation of antimicrobial humoral response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.
2006-09-22 GO:0002807 positive regulation of antimicrobial peptide biosynthetic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2006-09-22 GO:0002225 positive regulation of antimicrobial peptide production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of .
2006-09-22 GO:0002796 positive regulation of antimicrobial peptide secretion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.
2006-09-22 GO:0002230 positive regulation of defense response to virus by host Added DEFINITION Host processes that result in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
2006-09-22 GO:0002672 positive regulation of B cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell anergy.
2006-09-22 GO:0002624 positive regulation of B cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.
2006-09-22 GO:0002904 positive regulation of B cell apoptotic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell apoptosis.
2006-09-22 GO:0002723 positive regulation of B cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.
2006-09-22 GO:0002869 positive regulation of B cell deletion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell deletion.
2006-09-22 GO:0002714 positive regulation of B cell mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.
2006-09-22 GO:0002663 positive regulation of B cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.
2006-09-22 GO:0002693 positive regulation of cellular extravasation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cellular extravasation.
2006-09-22 GO:0032270 positive regulation of cellular protein metabolic process Added DEFINITION Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
2006-09-22 GO:0002916 positive regulation of central B cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central B cell anergy.
2006-09-22 GO:0002900 positive regulation of central B cell deletion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central B cell deletion.
2006-09-22 GO:0002897 positive regulation of central B cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.
2006-09-22 GO:0002648 positive regulation of central tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of central tolerance induction.
2006-09-22 GO:0002678 positive regulation of chronic inflammatory response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.
2006-09-22 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002882 positive regulation of chronic inflammatory response to non-antigenic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002744 positive regulation of cytokine biosynthetic process involved in immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cytokine biosynthesis during immune response.
2006-09-22 GO:0002720 positive regulation of cytokine production involved in immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cytokine production during immune response.
2006-09-22 GO:0002741 positive regulation of cytokine secretion involved in immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of cytokine secretion during immune response.
2006-09-22 GO:0002606 positive regulation of dendritic cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2006-09-22 GO:0002732 positive regulation of dendritic cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.
2006-09-22 GO:0002636 positive regulation of germinal center formation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of germinal center formation.
2006-09-22 GO:0002633 positive regulation of granuloma formation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of granuloma formation.
2006-09-22 GO:0002922 positive regulation of humoral immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
2006-09-22 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002250 adaptive immune response Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
2006-09-22 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory), as in, but not restricted to, the jawed vertebrates (Gnathostomata, ncbi_taxonomy_id:7776).
2006-09-22 GO:0002459 adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains Added DEFINITION An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory), as in, but not restricted to, hagfish and lamprays (Myxinidae, ncbi_taxonomy_id:7762, Petromyzontidae, ncbi_taxonomy_id:7746).
2006-09-22 GO:0048847 adenohypophysis formation Updated DEFINITION The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
2006-09-22 GO:0002299 alpha-beta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002287 alpha-beta T cell activation involved in immune response Added DEFINITION The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002293 alpha-beta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002363 alpha-beta T cell lineage commitment Added DEFINITION The process by which a pro-T cell becomes committed to becoming an alpha-beta T cell.
2006-09-22 GO:0002310 alpha-beta T cell proliferation involved in immune response Added DEFINITION The rapid expansion of an alpha-beta T cell population by cell division during an immune response.
2006-09-22 GO:0002564 alternate splicing of immunoglobulin genes Added DEFINITION The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.
2006-09-22 GO:0002500 proteolysis within lysosome associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.
2006-09-22 GO:0002497 proteasomal proteolysis associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by the proteosome complex contributing to antigen processing and presentation.
2006-09-22 GO:0032261 purine nucleotide salvage Added DEFINITION Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.
2006-09-22 GO:0032262 pyrimidine nucleotide salvage Added DEFINITION Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.
2006-09-22 GO:0009317 acetyl-CoA carboxylase complex Updated DEFINITION A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.
2006-09-22 GO:0002543 activation of blood coagulation via clotting cascade Added DEFINITION Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.
2006-09-22 GO:0002253 activation of immune response Added DEFINITION Any process that initiates an immune response.
2006-09-22 GO:0002218 activation of innate immune response Added DEFINITION Any process that initiates an innate immune response.
2006-09-22 GO:0002219 activation of innate immune response (sensu Viridiplantae) Added DEFINITION Any process that initiates an innate immune response as in, but not restricted to, green plants and algae (Viridiplantae, ncbi_taxonomy_id:33090).
2006-09-22 GO:0002541 activation of plasma proteins involved in acute inflammatory response Added DEFINITION Any process activating plasma proteins via proteolysis during an acute inflammatory response.
2006-09-22 GO:0002526 acute inflammatory response Added DEFINITION Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
2006-09-22 GO:0002438 acute inflammatory response to antigenic stimulus Added DEFINITION An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
2006-09-22 GO:0002525 acute inflammatory response to non-antigenic stimulus Added DEFINITION An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.
2006-09-22 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2006-09-22 GO:0002885 positive regulation of hypersensitivity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
2006-09-22 GO:0002699 positive regulation of immune effector process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of an immune effector process.
2006-09-22 GO:0002577 regulation of antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation.
2006-09-22 GO:0002598 regulation of antigen processing and presentation of lipid antigen via MHC class Ib Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
2006-09-22 GO:0002583 regulation of antigen processing and presentation of peptide antigen Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
2006-09-22 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
2006-09-22 GO:0002595 regulation of antigen processing and presentation of peptide antigen via MHC class Ib Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
2006-09-22 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2006-09-22 GO:0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2006-09-22 GO:0002601 regulation of antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2006-09-22 GO:0002592 regulation of antigen processing and presentation via MHC class Ib Added DEFINITION Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2006-09-22 GO:0002759 regulation of antimicrobial humoral response Added DEFINITION Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.
2006-09-22 GO:0002805 regulation of antimicrobial peptide biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2006-09-22 GO:0002793 positive regulation of peptide secretion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peptide secretion.
2006-09-22 GO:0002919 positive regulation of peripheral B cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.
2006-09-22 GO:0002910 positive regulation of peripheral B cell deletion Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.
2006-09-22 GO:0002851 positive regulation of peripheral T cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.
2006-09-22 GO:0002660 positive regulation of peripheral tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.
2006-09-22 GO:0002550 positive regulation of plasma kallikrein-kinin cascade Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
2006-09-22 GO:0002612 positive regulation of plasmacytoid dendritic cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002738 positive regulation of plasmacytoid dendritic cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2006-09-22 GO:0002702 positive regulation of production of molecular mediator of immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.
2006-09-22 GO:0032273 positive regulation of protein polymerization Added DEFINITION Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.
2006-09-22 GO:0002630 positive regulation of proteolysis associated with antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2006-09-22 GO:0002833 positive regulation of response to biotic stimulus Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
2006-09-22 GO:0002836 positive regulation of response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.
2006-09-22 GO:0002669 positive regulation of T cell anergy Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell anergy.
2006-09-22 GO:0002627 positive regulation of T cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.
2006-09-22 GO:0002726 positive regulation of T cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.
2006-09-22 GO:0002854 positive regulation of T cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
2006-09-22 GO:0002842 positive regulation of T cell mediated immune response to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
2006-09-22 GO:0002711 positive regulation of T cell mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.
2006-09-22 GO:0002666 positive regulation of T cell tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.
2006-09-22 GO:0002848 positive regulation of T cell tolerance induction to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.
2006-09-22 GO:0002827 positive regulation of T-helper 1 type immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.
2006-09-22 GO:0002830 positive regulation of type 2 immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of a T-helper 2 type immune response.
2006-09-22 GO:0002547 positive regulation of tissue kallikrein-kinin cascade Added DEFINITION Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
2006-09-22 GO:0002645 positive regulation of tolerance induction Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction.
2006-09-22 GO:0002654 positive regulation of tolerance induction dependent upon immune response Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.
2006-09-22 GO:0002657 positive regulation of tolerance induction to nonself antigen Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.
2006-09-22 GO:0002651 positive regulation of tolerance induction to self antigen Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.
2006-09-22 GO:0002845 positive regulation of tolerance induction to tumor cell Added DEFINITION Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.
2006-09-22 GO:0002894 positive regulation of type II hypersensitivity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.
2006-09-22 GO:0002331 pre-B cell allelic exclusion Added DEFINITION Expression of a single heavy chain allele during pre-B cell differentiation.
2006-09-22 GO:0002329 pre-B cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
2006-09-22 GO:0002412 antigen transcytosis by M cells in mucosal-associated lymphoid tissue Added DEFINITION The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.
2006-09-22 GO:0002777 antimicrobial peptide biosynthetic process Added DEFINITION The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2006-09-22 GO:0002775 antimicrobial peptide production Added DEFINITION The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2006-09-22 GO:0002776 antimicrobial peptide secretion Added DEFINITION The regulated release of an antimicrobial peptide from a cell or group of cells. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2006-09-22 GO:0002265 astrocyte activation involved in immune response Added DEFINITION A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002312 B cell activation involved in immune response Added DEFINITION The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2006-09-22 GO:0002344 B cell affinity maturation Added DEFINITION The process by which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.
2006-09-22 GO:0002515 B cell anergy Added DEFINITION Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
2006-09-22 GO:0002450 B cell antigen processing and presentation Added DEFINITION The process by which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2006-09-22 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
2006-09-22 GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
2006-09-22 GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.
2006-09-22 GO:0002618 positive regulation of macrophage antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.
2006-09-22 GO:0002907 positive regulation of mature B cell apoptotic process Added DEFINITION Any process that activates or increases the frequency, rate, or extent of mature B cell apoptosis.
2006-09-22 GO:0002615 positive regulation of monocyte antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.
2006-09-22 GO:0002609 positive regulation of myeloid dendritic cell antigen processing and presentation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002735 positive regulation of myeloid dendritic cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2006-09-22 GO:0002763 positive regulation of myeloid leukocyte differentiation Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
2006-09-22 GO:0002888 positive regulation of myeloid leukocyte mediated immunity Added DEFINITION Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2006-09-22 GO:0002729 positive regulation of natural killer cell cytokine production Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
2006-09-22 GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2006-09-22 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
2006-09-22 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.
2006-09-22 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002482 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
2006-09-22 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.
2006-09-22 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses an peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
2006-09-22 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.
2006-09-22 GO:0002505 antigen processing and presentation of polysaccharide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.
2006-09-22 GO:0002475 antigen processing and presentation via MHC class Ib Added DEFINITION The process by which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
2006-09-22 GO:0002405 antigen sampling by dendritic cells in mucosal-associated lymphoid tissue Added DEFINITION The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.
2006-09-22 GO:0002406 antigen sampling by M cells in mucosal-associated lymphoid tissue Added DEFINITION The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.
2006-09-22 GO:0002404 antigen sampling in mucosal-associated lymphoid tissue Added DEFINITION The process initiating the mucosal immune response which entails the apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.
2006-09-22 GO:0002330 pre-B cell receptor expression Added DEFINITION The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, including expression of the surrogate light chain, association of the surrogate light chain with heavy chain, and expression of the complete pre-B cell receptor on the cell surface.
2006-09-22 GO:0002328 pro-B cell differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
2006-09-22 GO:0002572 pro-T cell differentiation Added DEFINITION The process whereby an unspecialized hemopoietic stem cell acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
2006-09-22 GO:0002680 pro-T cell lineage commitment Added DEFINITION The process by which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.
2006-09-22 GO:0002538 arachidonic acid metabolite production involved in inflammatory response Added DEFINITION The synthesis or release of products of arachidonic acid metabolism following a stimulus during an acute inflammatory response, resulting in an increase in their intracellular or extracellular levels.
2006-09-22 GO:0002393 lysosomal enzyme production involved in inflammatory response Added DEFINITION The synthesis or release of lysosomal enzymes following a stimulus during an acute inflammatory response, resulting in an increase in intracellular or extracellular levels.
2006-09-22 GO:0002532 production of molecular mediator involved in inflammatory response Added DEFINITION The synthesis or release of any molecular mediator of the acute inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002440 production of molecular mediator of immune response Added DEFINITION The synthesis or release of any molecular mediator of the immune response following an immunological stimulus, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002537 nitric oxide production involved in inflammatory response Added DEFINITION The synthesis or release of nitric oxide following a stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002539 prostaglandin production involved in inflammatory response Added DEFINITION The synthesis or release of any prostaglandin following a stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002496 proteolysis associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.
2006-09-22 GO:0002203 proteolysis by cytosolic proteases associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.
2006-09-22 GO:0002498 proteolysis within endoplasmic reticulum associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.
2006-09-22 GO:0002499 proteolysis within endosome associated with antigen processing and presentation Added DEFINITION The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.
2006-09-22 GO:0002530 regulation of systemic arterial blood pressure involved in acute-phase response Added DEFINITION Any process that modulates the force with which blood travels through the circulatory system during the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
2006-09-22 GO:0002691 regulation of cellular extravasation Added DEFINITION Any process that modulates the frequency, rate, or extent of cellular extravasation.
2006-09-22 GO:0032268 regulation of cellular protein metabolic process Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
2006-09-22 GO:0002914 regulation of central B cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of central B cell anergy.
2006-09-22 GO:0002898 regulation of central B cell deletion Added DEFINITION Any process that modulates the frequency, rate, or extent of central B cell deletion.
2006-09-22 GO:0002895 regulation of central B cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.
2006-09-22 GO:0002646 regulation of central tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of central tolerance induction.
2006-09-22 GO:0002676 regulation of chronic inflammatory response Added DEFINITION Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.
2006-09-22 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002880 regulation of chronic inflammatory response to non-antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002742 regulation of cytokine biosynthetic process involved in immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of cytokine biosynthesis during immune response.
2006-09-22 GO:0002718 regulation of cytokine production involved in immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of cytokine production during immune response.
2006-09-22 GO:0002739 regulation of cytokine secretion involved in immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of cytokine secretion during immune response.
2006-09-22 GO:0002604 regulation of dendritic cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2006-09-22 GO:0002730 regulation of dendritic cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.
2006-09-22 GO:0002634 regulation of germinal center formation Added DEFINITION Any process that modulates the frequency, rate, or extent of germinal center formation.
2006-09-22 GO:0002631 regulation of granuloma formation Added DEFINITION Any process that modulates the frequency, rate, or extent of granuloma formation.
2006-09-22 GO:0002531 regulation of heart contraction involved in acute-phase response Added DEFINITION Any process that modulates the frequency, rate or extent of heart contraction during the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
2006-09-22 GO:0002920 regulation of humoral immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of a humoral immune response.
2006-09-22 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin Added DEFINITION Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2006-09-22 GO:0002883 regulation of hypersensitivity Added DEFINITION Any process that modulates the frequency, rate, or extent of hypersensitivity.
2006-09-22 GO:0002697 regulation of immune effector process Added DEFINITION Any process that modulates the frequency, rate, or extent of an immune effector process.
2006-09-22 GO:0002837 regulation of immune response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.
2006-09-22 GO:0002682 regulation of immune system process Added DEFINITION Any process that modulates the frequency, rate, or extent of an immune system process.
2006-09-22 GO:0010138 pyrimidine ribonucleotide salvage Updated DEFINITION The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.
2006-09-22 GO:0002673 regulation of acute inflammatory response Added DEFINITION Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
2006-09-22 GO:0002864 regulation of acute inflammatory response to antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
2006-09-22 GO:0002819 regulation of adaptive immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of an adaptive immune response.
2006-09-22 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Added DEFINITION Any process that modulates the frequency, rate, or extent of an adaptive immune response, as in, but not restricted to, the jawed vertebrates (Gnathostomata, ncbi_taxonomy_id:7776).
2006-09-22 GO:0002808 regulation of antibacterial peptide biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.
2006-09-22 GO:0002786 regulation of antibacterial peptide production Added DEFINITION Any process that modulates the frequency, rate, or extent of antibacterial peptide production.
2006-09-22 GO:0002797 regulation of antibacterial peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.
2006-09-22 GO:0002810 regulation of antifungal peptide biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.
2006-09-22 GO:0002788 regulation of antifungal peptide production Added DEFINITION Any process that modulates the frequency, rate, or extent of antifungal peptide production.
2006-09-22 GO:0002800 regulation of antifungal peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of .
2006-09-22 GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment Added DEFINITION The process by which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2006-09-22 GO:0002308 CD8-positive, alpha-beta cytotoxic T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
2006-09-22 GO:0002352 B cell negative selection Added DEFINITION Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.
2006-09-22 GO:0002346 B cell positive selection Added DEFINITION Any process by which B cells are selected to survive based on signaling through the B cell antigen receptor.
2006-09-22 GO:0002322 B cell proliferation involved in immune response Added DEFINITION The rapid expansion of a B cell population by cell division following B cell activation during an immune response.
2006-09-22 GO:0002452 B cell receptor editing Added DEFINITION The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.
2006-09-22 GO:0002339 B cell selection Added DEFINITION The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.
2006-09-22 GO:0002514 B cell tolerance induction Added DEFINITION A process involving any mechanism for tolerance induction in B cells.
2006-09-22 GO:0002402 B cell tolerance induction in mucosal-associated lymphoid tissue Added DEFINITION Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.
2006-09-22 GO:0002336 B-1 B cell lineage commitment Added DEFINITION The process by which an immature B cell becomes committed to become a B-1 B cell.
2006-09-22 GO:0002359 B-1 B cell proliferation Added DEFINITION The rapid expansion of a B-1 B cell by cell division. Follows B cell activation.
2006-09-22 GO:0002337 B-1a B cell differentiation Added DEFINITION The process whereby B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.
2006-09-22 GO:0002338 B-1b B cell differentiation Added DEFINITION The process whereby B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
2006-09-22 GO:0002276 basophil activation involved in immune response Added DEFINITION A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002575 basophil chemotaxis Added DEFINITION The movement of a basophil in response to an external stimulus.
2006-09-22 GO:0002561 basophil degranulation Added DEFINITION The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.
2006-09-22 GO:0002560 basophil mediated immunity Added DEFINITION Any process involved in the carrying out of an immune response by a mast cell.
2006-09-22 GO:0002209 behavioral defense response Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat to that organism.
2006-09-22 GO:0002211 behavioral defense response to insect Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.
2006-09-22 GO:0002212 behavioral defense response to nematode Added DEFINITION A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.
2006-09-22 GO:0002210 behavioral response to wounding Added DEFINITION A behavioral response resulting from wounding.
2006-09-22 GO:0002812 biosynthetic process of antibacterial peptides active against Gram-negative bacteria Added DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.
2006-09-22 GO:0002815 biosynthetic process of antibacterial peptides active against Gram-positive bacteria Added DEFINITION The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.
2006-09-22 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning Updated DEFINITION A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.
2006-09-22 GO:0002784 regulation of antimicrobial peptide production Added DEFINITION Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.
2006-09-22 GO:0002794 regulation of antimicrobial peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.
2006-09-22 GO:0002670 regulation of B cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell anergy.
2006-09-22 GO:0002622 regulation of B cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.
2006-09-22 GO:0002902 regulation of B cell apoptotic process Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell apoptosis.
2006-09-22 GO:0002721 regulation of B cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell cytokine production.
2006-09-22 GO:0002867 regulation of B cell deletion Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell deletion.
2006-09-22 GO:0002712 regulation of B cell mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
2006-09-22 GO:0002661 regulation of B cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of B cell tolerance induction.
2006-09-22 GO:0002813 regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria Added DEFINITION Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-negative bacteria.
2006-09-22 GO:0002816 regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Added DEFINITION Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against anti-Gram-positive bacteria.
2006-09-22 GO:0002761 regulation of myeloid leukocyte differentiation Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.
2006-09-22 GO:0002886 regulation of myeloid leukocyte mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2006-09-22 GO:0002727 regulation of natural killer cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.
2006-09-22 GO:0002858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2006-09-22 GO:0002855 regulation of natural killer cell mediated immune response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2006-09-22 GO:0002715 regulation of natural killer cell mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.
2006-09-22 GO:0002871 regulation of natural killer cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.
2006-09-22 GO:0002619 regulation of non-professional antigen presenting cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2006-09-22 GO:0002791 regulation of peptide secretion Added DEFINITION Any process that modulates the frequency, rate, or extent of peptide secretion.
2006-09-22 GO:0002917 regulation of peripheral B cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.
2006-09-22 GO:0002908 regulation of peripheral B cell deletion Added DEFINITION Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.
2006-09-22 GO:0002849 regulation of peripheral T cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.
2006-09-22 GO:0002300 CD8-positive, alpha-beta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002307 CD8-positive, alpha-beta regulatory T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.
2006-09-22 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002305 CD8-positive, gamma-delta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002263 cell activation involved in immune response Added DEFINITION A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2006-09-22 GO:0002421 B cell antigen processing and presentation following pinocytosis Added DEFINITION B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
2006-09-22 GO:0002417 B cell antigen processing and presentation mediated by B cell receptor uptake of antigen Added DEFINITION B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.
2006-09-22 GO:0002368 B cell cytokine production Added DEFINITION Any process that contributes to cytokine production by a B cell.
2006-09-22 GO:0002516 B cell deletion Added DEFINITION The apoptotic death of B cells which is part of B cell tolerance induction.
2006-09-22 GO:0002358 B cell homeostatic proliferation Added DEFINITION The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.
2006-09-22 GO:0002773 B cell inhibitory signaling pathway Added DEFINITION A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.
2006-09-22 GO:0002326 B cell lineage commitment Added DEFINITION The process whereby a lymphoid progenitor cell becomes committed to become any type of B cell.
2006-09-22 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002490 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2006-09-22 GO:0002491 antigen processing and presentation of endogenous peptide antigen via MHC class II Added DEFINITION The process by which an antigen-presenting cell expresses an peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
2006-09-22 GO:0002478 antigen processing and presentation of exogenous peptide antigen Added DEFINITION The process by which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.
2006-09-22 GO:0032166 chlamydospore septin filament array Updated DEFINITION Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.
2006-09-22 GO:0002544 chronic inflammatory response Added DEFINITION Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.
2006-09-22 GO:0002703 regulation of leukocyte mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
2006-09-22 GO:0002685 regulation of leukocyte migration Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte migration.
2006-09-22 GO:0002911 regulation of lymphocyte anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of lymphocyte anergy.
2006-09-22 GO:0002706 regulation of lymphocyte mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
2006-09-22 GO:0002616 regulation of macrophage antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.
2006-09-22 GO:0002905 regulation of mature B cell apoptotic process Added DEFINITION Any process that modulates the frequency, rate, or extent of mature B cell apoptosis.
2006-09-22 GO:0002613 regulation of monocyte antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.
2006-09-22 GO:0002607 regulation of myeloid dendritic cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2006-09-22 GO:0002733 regulation of myeloid dendritic cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2006-09-22 GO:0002736 regulation of plasmacytoid dendritic cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2006-09-22 GO:0002700 regulation of production of molecular mediator of immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.
2006-09-22 GO:0032271 regulation of protein polymerization Added DEFINITION Any process that modulates the frequency, rate or extent of the process of creating protein polymers.
2006-09-22 GO:0002628 regulation of proteolysis associated with antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2006-09-22 GO:0002831 regulation of response to biotic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
2006-09-22 GO:0002834 regulation of response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of a response to tumor cell.
2006-09-22 GO:0002667 regulation of T cell anergy Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell anergy.
2006-09-22 GO:0002625 regulation of T cell antigen processing and presentation Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.
2006-09-22 GO:0002724 regulation of T cell cytokine production Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell cytokine production.
2006-09-22 GO:0002852 regulation of T cell mediated cytotoxicity directed against tumor cell target Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
2006-09-22 GO:0002840 regulation of T cell mediated immune response to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
2006-09-22 GO:0002709 regulation of T cell mediated immunity Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell mediated immunity.
2006-09-22 GO:0002664 regulation of T cell tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell tolerance induction.
2006-09-22 GO:0002846 regulation of T cell tolerance induction to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.
2006-09-22 GO:0002825 regulation of T-helper 1 type immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.
2006-09-22 GO:0002828 regulation of type 2 immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of a T-helper 2 type immune response.
2006-09-22 GO:0002382 regulation of tissue kallikrein-kinin cascade Added DEFINITION Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
2006-09-22 GO:0002643 regulation of tolerance induction Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction.
2006-09-22 GO:0002652 regulation of tolerance induction dependent upon immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.
2006-09-22 GO:0002655 regulation of tolerance induction to nonself antigen Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.
2006-09-22 GO:0002649 regulation of tolerance induction to self antigen Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.
2006-09-22 GO:0002843 regulation of tolerance induction to tumor cell Added DEFINITION Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.
2006-09-22 GO:0002892 regulation of type II hypersensitivity Added DEFINITION Any process that modulates the frequency, rate, or extent of type II hypersensitivity.
2006-09-22 GO:0002528 regulation of vascular permeability involved in acute inflammatory response Added DEFINITION Any process that modulates the extent to which blood vessels can be pervaded by fluid during an acute inflammatory response.
2006-09-22 GO:0002536 respiratory burst involved in inflammatory response Added DEFINITION A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus during an acute inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.
2006-09-22 GO:0002679 respiratory burst involved in defense response Added DEFINITION A phase of elevated metabolic activity, during which oxygen consumption increases made as a defense reponse ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
2006-09-22 GO:0002237 response to molecule of bacterial origin Added DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of bacterial associated molecules such as peptides derived from bacterial flagellin.
2006-09-22 GO:0002238 response to molecule of fungal origin Added DEFINITION A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of fungal associated molecules such as chito-octomer oligosaccharide.
2006-09-22 GO:0032260 response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.
2006-09-22 GO:0002239 response to oomycetes Added DEFINITION A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.
2006-09-22 GO:0002439 chronic inflammatory response to antigenic stimulus Added DEFINITION A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.
2006-09-22 GO:0002545 chronic inflammatory response to non-antigenic stimulus Added DEFINITION A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.
2006-09-22 GO:0002247 clearance of damaged tissue involved in inflammatory response wound healing Added DEFINITION The series of events leading to removal of necrotic debris during or following an inflammatory response.
2006-09-22 GO:0002430 complement receptor mediated signaling pathway Added DEFINITION A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.
2006-09-22 GO:0002248 connective tissue replacement involved in inflammatory response wound healing Added DEFINITION The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared during or following an inflammatory response.
2006-09-22 GO:0002375 cytokine biosynthetic process involved in immune response Added DEFINITION The chemical reactions and pathways resulting in the formation of a cytokine during an immune response.
2006-09-22 GO:0002534 cytokine production involved in inflammatory response Added DEFINITION The synthesis or release of a cytokine following a inflammatory stimulus during an acute inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002367 cytokine production involved in immune response Added DEFINITION The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
2006-09-22 GO:0002374 cytokine secretion involved in immune response Added DEFINITION The regulated release of cytokines from a cell or group of cells during an immune response.
2006-09-22 GO:0002200 somatic diversification of immune receptors Added DEFINITION The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
2006-09-22 GO:0002569 somatic diversification of immune receptors by N region addition Added DEFINITION The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.
2006-09-22 GO:0002640 regulation of immunoglobulin biosynthetic process Added DEFINITION Any process that modulates the frequency, rate, or extent of immunoglobulin biosynthesis.
2006-09-22 GO:0002889 regulation of immunoglobulin mediated immune response Added DEFINITION Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
2006-09-22 GO:0002637 regulation of immunoglobulin production Added DEFINITION Any process that modulates the frequency, rate, or extent of immunoglobulin production.
2006-09-22 GO:0002861 regulation of inflammatory response to antigenic stimulus Added DEFINITION Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2006-09-22 GO:0002256 regulation of kinin cascade Added DEFINITION Any process that modulates the frequency, rate, or extent of the kinin cascade.
2006-09-22 GO:0002694 regulation of leukocyte activation Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte activation.
2006-09-22 GO:0002688 regulation of leukocyte chemotaxis Added DEFINITION Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.
2006-09-22 GO:0002306 CD4-positive gamma-delta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002301 CD4-positive, alpha-beta intraepithelial T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2006-09-22 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2006-09-22 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation Added DEFINITION The process whereby a relatively unspecialized hemopoietic stem cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2006-09-22 GO:0002298 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response Added DEFINITION The process whereby an antigenically nave CD4-positive, alpha-beta T cell acquires the specialized features of an CD4-positive, CD25-positive, alpha-beta regulatory T cell during an immune response.
2006-09-22 GO:0002774 Fc receptor mediated inhibitory signaling pathway Added DEFINITION A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
2006-09-22 GO:0002431 Fc receptor mediated stimulatory signaling pathway Added DEFINITION A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
2006-09-22 GO:0048810 female analia morphogenesis Updated DEFINITION The process by which the anatomical structures of the analia of the female are generated and organized. Morphogenesis pertains to the creation of form. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2006-09-22 GO:0002553 histamine secretion by mast cell Added DEFINITION The regulated release of histamine by a mast cell or group of mast cells.
2006-09-22 GO:0002555 histamine secretion by platelet Added DEFINITION The regulated release of histamine by a platelet or group of platelets.
2006-09-22 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway Added DEFINITION Any series of molecular signals generated as a consequence of binding to a cytoplasmic pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
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