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GO Term History: Displaying 75 audit records for all terms for the date 2006-08-22

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-08-22 GO:0021595 rhombomere structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0032167 septin patch Updated DEFINITION OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis.
2006-08-22 GO:0019787 small conjugating protein ligase activity Updated DEFINITION Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of a small conjugahting protein such as ubiquitin or a ubiquitin-like protein, and a substrate lysine residue.
2006-08-22 GO:0008641 small protein activating enzyme activity Updated DEFINITION Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
2006-08-22 GO:0021763 subthalamic nucleus development Updated DEFINITION The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.
2006-08-22 GO:0021725 superior raphe nucleus development Updated DEFINITION The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.
2006-08-22 GO:0022029 telencephalon cell migration Updated DEFINITION The orderly movement of cells from one site to another at least one of which is located in the telencephalon.
2006-08-22 GO:0021558 trochlear nerve development Updated DEFINITION The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021642 trochlear nerve formation Updated DEFINITION The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021640 trochlear nerve maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021639 trochlear nerve morphogenesis Updated DEFINITION The process by which the anatomical structure of the trochlear nerve is generated and organized. Morphogenesis pertains to the creation of form. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021641 trochlear nerve structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021962 vestibulospinal tract morphogenesis Updated DEFINITION Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.
2006-08-22 GO:0021932 hindbrain radial glia guided cell migration Updated DEFINITION The radially directed movement of cells along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.
2006-08-22 GO:0048851 hypophysis formation Added DEFINITION The process by which the anatomical structures of the hypophysis are generated and organized. Morphogenesis pertains to the creation of form. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.
2006-08-22 GO:0032132 O6-alkylguanine-DNA binding Updated DEFINITION Interacting selectively with O6-alkylguanine adducts in DNA.
2006-08-22 GO:0048850 hypophysis morphogenesis Added DEFINITION The process by which the anatomical structures of the hypophysis are generated and organized. Morphogenesis pertains to the creation of form. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
2006-08-22 GO:0021856 hypothalamic tangential migration using cell-axon interactions Updated DEFINITION The movement of hypothalamic neuronal precursors tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.
2006-08-22 GO:0021916 inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors Updated DEFINITION Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.
2006-08-22 GO:0021713 inferior olivary nucleus development Updated DEFINITION The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021715 inferior olivary nucleus formation Updated DEFINITION The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021717 inferior olivary nucleus maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021714 inferior olivary nucleus morphogenesis Updated DEFINITION The process by which the anatomical structure of the inferior olivary nucleus is generated and organized. Morphogenesis pertains to the creation of form. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021716 inferior olivary nucleus structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0014005 microglia development Updated DEFINITION The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-08-22 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.
2006-08-22 GO:0021503 neural fold bending Updated DEFINITION The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.
2006-08-22 GO:0021502 neural fold elevation formation Updated DEFINITION The process by which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.
2006-08-22 GO:0021505 neural fold folding Updated DEFINITION The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.
2006-08-22 GO:0021504 neural fold hinge point formation Updated DEFINITION The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.
2006-08-22 GO:0021985 neurohypophysis development Updated DEFINITION The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
2006-08-22 GO:0048849 neurohypophysis formation Added DEFINITION The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts.The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
2006-08-22 GO:0048848 neurohypophysis morphogenesis Added DEFINITION The process by which the anatomical structures of neurohypophysis are generated and organized. Morphogenesis pertains to the creation of form. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
2006-08-22 GO:0021557 oculomotor nerve development Updated DEFINITION The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021623 oculomotor nerve formation Updated DEFINITION The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021625 oculomotor nerve maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021622 oculomotor nerve morphogenesis Updated DEFINITION The process by which the anatomical structure of the oculomotor nerve is generated and organized. Morphogenesis pertains to the creation of form. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021624 oculomotor nerve structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021989 olfactory cortex development Updated DEFINITION The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.
2006-08-22 GO:0021554 optic nerve development Updated DEFINITION The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021634 optic nerve formation Updated DEFINITION The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021632 optic nerve maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021631 optic nerve morphogenesis Updated DEFINITION The process by which the anatomical structure of the optic nerve is generated and organized. Morphogenesis pertains to the creation of form. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021633 optic nerve structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0048645 organ formation Updated DEFINITION The process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.
2006-08-22 GO:0021982 pineal gland development Updated DEFINITION The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.
2006-08-22 GO:0021548 pons development Updated DEFINITION The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021584 pons formation Updated DEFINITION The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021586 pons maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021583 pons morphogenesis Updated DEFINITION The process by which the anatomical structure of the pons is generated and organized. Morphogenesis pertains to the creation of form. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021975 pons reticulospinal tract morphogenesis Updated DEFINITION Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.
2006-08-22 GO:0021585 pons structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway Updated DEFINITION The initiation of the activity of the inactive enzyme protein kinase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
2006-08-22 GO:0002082 regulation of oxidative phosphorylation Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2006-08-22 GO:0021662 rhombomere 4 structural organization Updated DEFINITION The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
2006-08-22 GO:0022035 rhombomere cell migration Updated DEFINITION The movement of cells within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.
2006-08-22 GO:0021546 rhombomere development Updated DEFINITION The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0021594 rhombomere formation Updated DEFINITION The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0021593 rhombomere morphogenesis Updated DEFINITION The process by which the anatomical structure of the rhombomere is generated and organized. Morphogenesis pertains to the creation of form. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0048847 adenohypophysis formation Added DEFINITION The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts.The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
2006-08-22 GO:0048855 adenohypophysis morphogenesis Added DEFINITION The process by which the anatomical structures of the adenohypophysis are generated and organized. Morphogenesis pertains to the creation of form. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
2006-08-22 GO:0021777 BMP signaling pathway involved in spinal cord association neuron specification Updated DEFINITION A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to its commitment to an association neuron fate.
2006-08-22 GO:0048854 brain morphogenesis Added DEFINITION The process by which the anatomical structures of brain are generated and organized. Morphogenesis pertains to the creation of form. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2006-08-22 GO:0021533 cell differentiation in hindbrain Updated DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2006-08-22 GO:0021923 cell proliferation in hindbrain ventricular zone Updated DEFINITION The multiplication or reproduction of cells, resulting in the rapid expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.
2006-08-22 GO:0021824 cerebral cortex tangential migration using cell-axon interactions Updated DEFINITION The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.
2006-08-22 GO:0021823 cerebral cortex tangential migration using cell-cell interactions Updated DEFINITION The process whereby neurons interact with each other to promote migration along a tangential plane.
2006-08-22 GO:0021927 deep nuclear neuron precursor proliferation Updated DEFINITION The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.
2006-08-22 GO:0021542 dentate gyrus development Updated DEFINITION The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
2006-08-22 GO:0048852 diencephalon morphogenesis Added DEFINITION The process by which the anatomical structures of diencephalon are generated and organized. Morphogenesis pertains to the creation of form. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
2006-08-22 GO:0021901 early neuron fate commitment in forebrain Updated DEFINITION The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.
2006-08-22 GO:0021885 forebrain cell migration Updated DEFINITION The orderly movement of cells from one site to another at least one of which is located in the forebrain.
2006-08-22 GO:0048853 forebrain morphogenesis Added DEFINITION The process by which the anatomical structures of the forebrain are generated and organized. Morphogenesis pertains to the creation of form. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
2006-08-22 GO:0021943 formation of radial glial scaffolds Updated DEFINITION The formation of scaffolds from radial glial cells. The scaffolds are used as a substrate for the radial migration of cells.
2006-08-22 GO:0021984 adenohypophysis development Updated DEFINITION The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-08-22 GO:0021595 rhombomere structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0032167 septin patch Updated DEFINITION OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis.
2006-08-22 GO:0019787 small conjugating protein ligase activity Updated DEFINITION Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of a small conjugahting protein such as ubiquitin or a ubiquitin-like protein, and a substrate lysine residue.
2006-08-22 GO:0008641 small protein activating enzyme activity Updated DEFINITION Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
2006-08-22 GO:0021763 subthalamic nucleus development Updated DEFINITION The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.
2006-08-22 GO:0021725 superior raphe nucleus development Updated DEFINITION The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.
2006-08-22 GO:0022029 telencephalon cell migration Updated DEFINITION The orderly movement of cells from one site to another at least one of which is located in the telencephalon.
2006-08-22 GO:0021558 trochlear nerve development Updated DEFINITION The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021642 trochlear nerve formation Updated DEFINITION The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021640 trochlear nerve maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021639 trochlear nerve morphogenesis Updated DEFINITION The process by which the anatomical structure of the trochlear nerve is generated and organized. Morphogenesis pertains to the creation of form. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021641 trochlear nerve structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
2006-08-22 GO:0021962 vestibulospinal tract morphogenesis Updated DEFINITION Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.
2006-08-22 GO:0021932 hindbrain radial glia guided cell migration Updated DEFINITION The radially directed movement of cells along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.
2006-08-22 GO:0048851 hypophysis formation Added DEFINITION The process by which the anatomical structures of the hypophysis are generated and organized. Morphogenesis pertains to the creation of form. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.
2006-08-22 GO:0032132 O6-alkylguanine-DNA binding Updated DEFINITION Interacting selectively with O6-alkylguanine adducts in DNA.
2006-08-22 GO:0048850 hypophysis morphogenesis Added DEFINITION The process by which the anatomical structures of the hypophysis are generated and organized. Morphogenesis pertains to the creation of form. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
2006-08-22 GO:0021856 hypothalamic tangential migration using cell-axon interactions Updated DEFINITION The movement of hypothalamic neuronal precursors tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.
2006-08-22 GO:0021916 inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors Updated DEFINITION Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.
2006-08-22 GO:0021713 inferior olivary nucleus development Updated DEFINITION The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021715 inferior olivary nucleus formation Updated DEFINITION The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021717 inferior olivary nucleus maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021714 inferior olivary nucleus morphogenesis Updated DEFINITION The process by which the anatomical structure of the inferior olivary nucleus is generated and organized. Morphogenesis pertains to the creation of form. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0021716 inferior olivary nucleus structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
2006-08-22 GO:0014005 microglia development Updated DEFINITION The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2006-08-22 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.
2006-08-22 GO:0021503 neural fold bending Updated DEFINITION The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.
2006-08-22 GO:0021502 neural fold elevation formation Updated DEFINITION The process by which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.
2006-08-22 GO:0021505 neural fold folding Updated DEFINITION The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.
2006-08-22 GO:0021504 neural fold hinge point formation Updated DEFINITION The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.
2006-08-22 GO:0021985 neurohypophysis development Updated DEFINITION The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
2006-08-22 GO:0048849 neurohypophysis formation Added DEFINITION The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts.The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
2006-08-22 GO:0048848 neurohypophysis morphogenesis Added DEFINITION The process by which the anatomical structures of neurohypophysis are generated and organized. Morphogenesis pertains to the creation of form. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
2006-08-22 GO:0021557 oculomotor nerve development Updated DEFINITION The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021623 oculomotor nerve formation Updated DEFINITION The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021625 oculomotor nerve maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021622 oculomotor nerve morphogenesis Updated DEFINITION The process by which the anatomical structure of the oculomotor nerve is generated and organized. Morphogenesis pertains to the creation of form. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021624 oculomotor nerve structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
2006-08-22 GO:0021989 olfactory cortex development Updated DEFINITION The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.
2006-08-22 GO:0021554 optic nerve development Updated DEFINITION The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021634 optic nerve formation Updated DEFINITION The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021632 optic nerve maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021631 optic nerve morphogenesis Updated DEFINITION The process by which the anatomical structure of the optic nerve is generated and organized. Morphogenesis pertains to the creation of form. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0021633 optic nerve structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
2006-08-22 GO:0048645 organ formation Updated DEFINITION The process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.
2006-08-22 GO:0021982 pineal gland development Updated DEFINITION The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.
2006-08-22 GO:0021548 pons development Updated DEFINITION The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021584 pons formation Updated DEFINITION The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021586 pons maturation Updated DEFINITION A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021583 pons morphogenesis Updated DEFINITION The process by which the anatomical structure of the pons is generated and organized. Morphogenesis pertains to the creation of form. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0021975 pons reticulospinal tract morphogenesis Updated DEFINITION Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.
2006-08-22 GO:0021585 pons structural organization Updated DEFINITION The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
2006-08-22 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway Updated DEFINITION The initiation of the activity of the inactive enzyme protein kinase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
2006-08-22 GO:0002082 regulation of oxidative phosphorylation Added DEFINITION Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2006-08-22 GO:0021662 rhombomere 4 structural organization Updated DEFINITION The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
2006-08-22 GO:0022035 rhombomere cell migration Updated DEFINITION The movement of cells within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.
2006-08-22 GO:0021546 rhombomere development Updated DEFINITION The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0021594 rhombomere formation Updated DEFINITION The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0021593 rhombomere morphogenesis Updated DEFINITION The process by which the anatomical structure of the rhombomere is generated and organized. Morphogenesis pertains to the creation of form. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
2006-08-22 GO:0048847 adenohypophysis formation Added DEFINITION The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts.The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
2006-08-22 GO:0048855 adenohypophysis morphogenesis Added DEFINITION The process by which the anatomical structures of the adenohypophysis are generated and organized. Morphogenesis pertains to the creation of form. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
2006-08-22 GO:0021777 BMP signaling pathway involved in spinal cord association neuron specification Updated DEFINITION A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to its commitment to an association neuron fate.
2006-08-22 GO:0048854 brain morphogenesis Added DEFINITION The process by which the anatomical structures of brain are generated and organized. Morphogenesis pertains to the creation of form. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2006-08-22 GO:0021533 cell differentiation in hindbrain Updated DEFINITION The process whereby relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
2006-08-22 GO:0021923 cell proliferation in hindbrain ventricular zone Updated DEFINITION The multiplication or reproduction of cells, resulting in the rapid expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.
2006-08-22 GO:0021824 cerebral cortex tangential migration using cell-axon interactions Updated DEFINITION The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.
2006-08-22 GO:0021823 cerebral cortex tangential migration using cell-cell interactions Updated DEFINITION The process whereby neurons interact with each other to promote migration along a tangential plane.
2006-08-22 GO:0021927 deep nuclear neuron precursor proliferation Updated DEFINITION The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.
2006-08-22 GO:0021542 dentate gyrus development Updated DEFINITION The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
2006-08-22 GO:0048852 diencephalon morphogenesis Added DEFINITION The process by which the anatomical structures of diencephalon are generated and organized. Morphogenesis pertains to the creation of form. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
2006-08-22 GO:0021901 early neuron fate commitment in forebrain Updated DEFINITION The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.
2006-08-22 GO:0021885 forebrain cell migration Updated DEFINITION The orderly movement of cells from one site to another at least one of which is located in the forebrain.
2006-08-22 GO:0048853 forebrain morphogenesis Added DEFINITION The process by which the anatomical structures of the forebrain are generated and organized. Morphogenesis pertains to the creation of form. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
2006-08-22 GO:0021943 formation of radial glial scaffolds Updated DEFINITION The formation of scaffolds from radial glial cells. The scaffolds are used as a substrate for the radial migration of cells.
2006-08-22 GO:0021984 adenohypophysis development Updated DEFINITION The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
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