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GO Term History: Displaying 254 audit records for all terms for the date 2006-02-04

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-02-04 GO:0030586 [methionine synthase] reductase activity Updated DEFINITION Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.
2006-02-04 GO:0047081 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NAD(P)H + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NAD(P)+ + 2-(acetamidomethylene)succinate.
2006-02-04 GO:0047048 3-hydroxybenzyl-alcohol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 3-hydroxybenzyl alcohol = NADPH + H+ + 3-hydroxybenzaldehyde.
2006-02-04 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity Updated DEFINITION Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].
2006-02-04 GO:0047136 4-(dimethylamino)phenylazoxybenzene reductase activity Updated DEFINITION Catalysis of the reaction: 4-dimethylaminophenylazobenzene + NADP+ = 4-(dimethylamino)phenylazoxybenzene + NADPH + H+.
2006-02-04 GO:0047162 17-O-deacetylvindoline O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: 17-O-deacetylvindoline + acetyl-CoA = vindoline + CoA.
2006-02-04 GO:0008666 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Updated DEFINITION Catalysis of the reaction: succinyl-CoA + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.
2006-02-04 GO:0047189 2,3-diaminopropionate N-oxalyltransferase activity Updated DEFINITION Catalysis of the reaction: L-2,3-diaminopropanoate + oxalyl-CoA = N3-oxalyl-L-23-diaminopropanoate + CoA.
2006-02-04 GO:0018542 2,3-dihydroxy DDT 1,2-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.
2006-02-04 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.
2006-02-04 GO:0047190 2-acylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.
2006-02-04 GO:0018626 2-chlorobenzoate 1,2-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.
2006-02-04 GO:0047000 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 2-dehydro-3-deoxy-D-gluconate = NADPH + H+ + (4S,5S)-4,5-dehydroxy-2,6-dioxohexanoate.
2006-02-04 GO:0050625 2-hydroxy-1,4-benzoquinone reductase activity Updated DEFINITION Catalysis of the reaction: hydroxybenzoquinone + NADH + H+ = 1,2,4-trihydroxybenzene + NAD+.
2006-02-04 GO:0019142 2-hydroxyglutarate synthase activity Updated DEFINITION Catalysis of the reaction: propanoyl-CoA + H2O + glyoxylate = 2-hydroxyglutarate + CoA.
2006-02-04 GO:0003852 2-isopropylmalate synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA.
2006-02-04 GO:0047101 2-oxoisovalerate dehydrogenase (acylating) activity Updated DEFINITION Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.
2006-02-04 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.
2006-02-04 GO:0047007 pregnan-21-ol dehydrogenase (NAD+) activity Updated DEFINITION Catalysis of the reaction: NAD+ + pregnan-21-ol = NADH + H+ + pregnan-21-al.
2006-02-04 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + pregnan-21-ol = NADPH + H+ + pregnan-21-al.
2006-02-04 GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process Updated DEFINITION The formation from simpler components of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
2006-02-04 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process Updated DEFINITION The chemical reactions involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
2006-02-04 GO:0047023 androsterone dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
2006-02-04 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Updated DEFINITION Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.
2006-02-04 GO:0047163 3,4-dichloroaniline N-malonyltransferase activity Updated DEFINITION Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonate + CoA.
2006-02-04 GO:0047035 testosterone dehydrogenase (NAD+) activity Updated DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2006-02-04 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.
2006-02-04 GO:0047477 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA + pyrophosphate + AMP.
2006-02-04 GO:0047476 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + pyrophosphate + AMP.
2006-02-04 GO:0047009 3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.
2006-02-04 GO:0047043 3-alpha-hydroxycholanate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-cholanate = NADH + H+ + 3-oxo-5-beta-cholanate.
2006-02-04 GO:0047032 3-alpha-hydroxyglycyrrhetinate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 3-alpha-hydroxyglycyrrhetinate = NADPH + H+ + 3-oxoglycyrrhetinate.
2006-02-04 GO:0047026 androsterone dehydrogenase (A-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
2006-02-04 GO:0047042 androsterone dehydrogenase (B-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
2006-02-04 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 5-alpha-androstan-3-beta,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADPH + H+.
2006-02-04 GO:0046565 3-dehydroshikimate dehydratase activity Updated DEFINITION Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate (protocatechuate) + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.
2006-02-04 GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity Updated DEFINITION Catalysis of the reaction: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate.
2006-02-04 GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
2006-02-04 GO:0018497 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity Updated DEFINITION Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.
2006-02-04 GO:0047013 cholate 12-alpha dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate = NADPH + H+ + 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate.
2006-02-04 GO:0047203 13-hydroxylupinine O-tigloyltransferase activity Updated DEFINITION Catalysis of the reaction: 13-hydroxylupinine + (E)-2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyl)oxylupinine + CoA.
2006-02-04 GO:0047034 15-hydroxyicosatetraenoate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.
2006-02-04 GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate = NADPH + H+ + (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate.
2006-02-04 GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.
2006-02-04 GO:0047033 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-dienoate.
2006-02-04 GO:0047005 16-alpha-hydroxysteroid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.
2006-02-04 GO:0018622 4-chlorophenylacetate 3,4-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 4-chlorophenyl acetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+.
2006-02-04 GO:0047030 4-hydroxycyclohexanecarboxylate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 4-hydroxycyclohexanecarboxylate = NADH + H+ + 4-oxocyclohexanecarboxylate.
2006-02-04 GO:0047106 4-hydroxyphenylacetaldehyde dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate.
2006-02-04 GO:0047083 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate.
2006-02-04 GO:0018770 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity Updated DEFINITION Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate + H2O = 2-(4-chlorophenyl)-3,3-dichloropropenoate.
2006-02-04 GO:0047028 6-pyruvoyltetrahydropterin 2'-reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.
2006-02-04 GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + 7-beta-hydroxysteroid = NADPH + H+ + 7-oxosteroid.
2006-02-04 GO:0003984 acetolactate synthase activity Updated DEFINITION Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.
2006-02-04 GO:0018710 acetone carboxylase activity Updated DEFINITION Catalysis of the reaction: acetone + ATP + 2 H2O + CO2 = AMP + 2 phosphate + acetoacetate.
2006-02-04 GO:0004017 adenylate kinase activity Updated DEFINITION Catalysis of the reaction: ATP + AMP = 2 ADP.
2006-02-04 GO:0004020 adenylylsulfate kinase activity Updated DEFINITION Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
2006-02-04 GO:0051061 ADP reductase activity Updated DEFINITION Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.
2006-02-04 GO:0047380 ADP-dependent medium-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + acyl-CoA = an acid + CoA.
2006-02-04 GO:0047379 ADP-dependent short-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + acyl-CoA = an acid + CoA.
2006-02-04 GO:0004027 alcohol sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
2006-02-04 GO:0008726 alkanesulfonate monooxygenase activity Updated DEFINITION Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + SO3(2-) (sulfite) + H2O + FMN.
2006-02-04 GO:0050698 proteoglycan sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.
2006-02-04 GO:0050226 psychosine sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate.
2006-02-04 GO:0047040 pteridine reductase activity Updated DEFINITION Catalysis of the reaction: 2 NADP+ + tetra-hydro-biopterin = 2 NADPH + 2 H+ + biopterin.
2006-02-04 GO:0047174 putrescine N-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: putrescine + caffeoyl-CoA = N-caffeoylputrescine + CoA.
2006-02-04 GO:0047367 quercetin-3,3'-bissulfate 7-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047365 quercetin-3-sulfate 3'-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: quercetin 3-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3'-bissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047366 quercetin-3-sulfate 4'-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: quercetin 3-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,4'-bissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047205 quinate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.
2006-02-04 GO:0050249 Renilla-luciferin sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + Renilla luciferin = adenosine 3',5'-bisphosphate + luciferyl sulfate.
2006-02-04 GO:0017051 retinol dehydratase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.
2006-02-04 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Updated DEFINITION Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0008998 ribonucleoside-triphosphate reductase activity Updated DEFINITION Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.
2006-02-04 GO:0016984 ribulose-bisphosphate carboxylase activity Updated DEFINITION Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate.
2006-02-04 GO:0047037 salutaridine reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NADP+ + salutaridinol = NADPH + H+ + salutaridine.
2006-02-04 GO:0047055 salutaridine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + (R)-reticuline = 2 H2O + NADP+ + salutaridine.
2006-02-04 GO:0047077 Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity Updated DEFINITION Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + pyrophosphate + AMP + CO2 + oxidized Photinus luciferin.
2006-02-04 GO:0018620 phthalate 4,5-dioxygenase activity Updated DEFINITION Catalysis of the reaction: phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+.
2006-02-04 GO:0047166 1-alkenylglycerophosphoethanolamine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.
2006-02-04 GO:0047167 1-alkyl-2-acetylglycerol O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.
2006-02-04 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.
2006-02-04 GO:0047191 1-alkylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA.
2006-02-04 GO:0018827 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity Updated DEFINITION Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.
2006-02-04 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.
2006-02-04 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine 4-sulfate (in chondroitin sulfate) = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4,6-bissulfate. Functions on nonreducing terminal and internal GalNAc(4SO(4)) residues contained in chondroitin sulfate A and dermatan sulfate (chondroitin sulfate B).
2006-02-04 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.
2006-02-04 GO:0047185 N-acetylneuraminate 4-O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.
2006-02-04 GO:0047186 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.
2006-02-04 GO:0047444 N-acylneuraminate-9-phosphate synthase activity Updated DEFINITION Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.
2006-02-04 GO:0047137 N-hydroxy-2-acetamidofluorene reductase activity Updated DEFINITION Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+.
2006-02-04 GO:0003958 NADPH-hemoprotein reductase activity Updated DEFINITION Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.
2006-02-04 GO:0050140 nitrate reductase (cytochrome) activity Updated DEFINITION Catalysis of the reaction: ferrocytochrome + NO3- (nitrate) = ferricytochrome + NO2- (nitrite).
2006-02-04 GO:0009703 nitrate reductase (NADH) activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + NAD+ + H2O = NO3- (nitrate) + NADH + H+.
2006-02-04 GO:0050464 nitrate reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + NADP+ + H2O = NO3- (nitrate) + NADPH + H+.
2006-02-04 GO:0047180 salutaridinol 7-O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: salutaridinol + acetyl-CoA = 7-O-acetylsalutaridinol + CoA.
2006-02-04 GO:0047172 shikimate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.
2006-02-04 GO:0004768 stearoyl-CoA 9-desaturase activity Updated DEFINITION Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O.
2006-02-04 GO:0050294 steroid sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate.
2006-02-04 GO:0047012 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one.
2006-02-04 GO:0008146 sulfotransferase activity Updated DEFINITION Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.
2006-02-04 GO:0047161 tartronate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: 2-hydroxymalonate + sinapoyl-CoA = sinapoyltartronate + CoA.
2006-02-04 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.
2006-02-04 GO:0047200 tetrahydrodipicolinate N-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: L-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA = L-2-acetamido-6-oxoheptanedioate + CoA.
2006-02-04 GO:0030269 tetrahydromethanopterin S-methyltransferase activity Updated DEFINITION Catalysis of the reaction: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate. 2-(methylthio)ethanesulfonate is also known as methyl-CoM.
2006-02-04 GO:0047039 tetrahydroxynaphthalene reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.
2006-02-04 GO:0018760 thiocyanate hydrolase activity Updated DEFINITION Catalysis of the reaction: thiocyanate + H2O = NH3 + carbonyl sulfide.
2006-02-04 GO:0009031 thiol peroxidase activity Updated DEFINITION Catalysis of the reaction: thioredoxin + H2O2 = thioredoxin disulfide + H2O.
2006-02-04 GO:0050603 thiophene-2-carbonyl-CoA monooxygenase activity Updated DEFINITION Catalysis of the reaction: thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O.
2006-02-04 GO:0008379 thioredoxin peroxidase activity Updated DEFINITION Catalysis of the reaction: thioredoxin + H2O2 = thioredoxin disulfide + H2O.
2006-02-04 GO:0050797 thymidylate synthase (FAD) activity Updated DEFINITION Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + FADH2 = dTMP + tetrahydrofolate + FAD.
2006-02-04 GO:0004800 thyroxine 5'-deiodinase activity Updated DEFINITION Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
2006-02-04 GO:0047062 trans-acenaphthene-1,2-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + (+-)-trans-acenaphthene-1,2-diol = NADPH + H+ + acenaphthenequinone.
2006-02-04 GO:0030133 transport vesicle Updated DEFINITION Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, and to destinations within or outside the cell.
2006-02-04 GO:0047363 triglucosylalkylacylglycerol sulfotransferase activity Updated DEFINITION Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0015042 trypanothione-disulfide reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.
2006-02-04 GO:0004510 tryptophan 5-monooxygenase activity Updated DEFINITION Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
2006-02-04 GO:0051064 TTP reductase activity Updated DEFINITION Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0004511 tyrosine 3-monooxygenase activity Updated DEFINITION Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
2006-02-04 GO:0017067 tyrosine-ester sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate.
2006-02-04 GO:0051062 UDP reductase activity Updated DEFINITION Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.
2006-02-04 GO:0047368 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity Updated DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine 4-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = UDP-N-acetyl-D-galactosamine 4,6-bissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047004 UDP-N-acetylglucosamine 6-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: H2O + 2 NAD+ + UDP-N-acetyl-D-glucosamine = 2 NADH + 2 H+ + UDP-N-acetyl-2-amino-d-glucuronate.
2006-02-04 GO:0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity Updated DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2006-02-04 GO:0018487 vanillate O-demethylase (anaerobic) activity Updated DEFINITION Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.
2006-02-04 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-desulfoheparin = adenosine 3',5'-bisphosphate + heparin.
2006-02-04 GO:0047889 ferredoxin-nitrate reductase activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + H2O + 2 oxidized ferredoxin = NO3- (nitrate) + 2 reduced ferredoxin.
2006-02-04 GO:0048307 ferredoxin-nitrite reductase activity Updated DEFINITION Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = NO2(-) (nitrite) + 6 reduced ferredoxin + 7 H+.
2006-02-04 GO:0000293 ferric-chelate reductase activity Updated DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2006-02-04 GO:0047894 flavonol 3-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + quercetin = adenosine 3',5'-bisphosphate + quercetin 3-sulfate.
2006-02-04 GO:0008940 nitrate reductase activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + acceptor = NO3- (nitrate) + reduced acceptor.
2006-02-04 GO:0050463 nitrate reductase [NAD(P)H] activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + NAD(P)+ + H2O = NO3- (nitrate) + NAD(P)H + H+.
2006-02-04 GO:0008941 nitric oxide dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 NO3- + NADP+.
2006-02-04 GO:0047047 oxaloglycolate reductase (decarboxylating) activity Updated DEFINITION Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate.
2006-02-04 GO:0018548 pentaerythritol trinitrate reductase activity Updated DEFINITION Catalysis of the reaction: pentaerythritol tri(or tetra)nitrate + NADPH = NADP+ + NO3- (nitrate) + pentaerythritol di(or tri)nitrate.
2006-02-04 GO:0008955 peptidoglycan glycosyltransferase activity Updated DEFINITION Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.
2006-02-04 GO:0047475 phenylacetate-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + phenylacetate + ATP = phenylacetyl-CoA + products of ATP breakdown.
2006-02-04 GO:0004505 phenylalanine 4-monooxygenase activity Updated DEFINITION Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
2006-02-04 GO:0047110 phenylglyoxylate dehydrogenase (acylating) activity Updated DEFINITION Catalysis of the reaction: CoA + NAD+ + phenylglyoxylate = NADH + CO2 + benzoyl-S-CoA.
2006-02-04 GO:0004604 phosphoadenylyl-sulfate reductase (thioredoxin) activity Updated DEFINITION Catalysis of the reaction: adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenosine 5'-phosphosulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
2006-02-04 GO:0050186 phosphoadenylylsulfatase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + SO4(2-) (sulfate).
2006-02-04 GO:0004689 phosphorylase kinase activity Updated DEFINITION Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.
2006-02-04 GO:0047049 (R)-2-hydroxy-fatty acid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + R-2-hydroxystearate = NADH + H+ + 2-oxostearate.
2006-02-04 GO:0047029 (R)-4-hydroxyphenyllactate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + H+ + 3-(4-hydroxyphenyl)pyruvate.
2006-02-04 GO:0047050 (S)-2-hydroxy-fatty acid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + (S)-2-hydroxystearate = NADH + H+ + 2-oxostearate.
2006-02-04 GO:0047056 (S)-canadine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + S-tetrahydrocolumbamine = 2 H2O + NADP+ + S-canadine.
2006-02-04 GO:0047041 (S)-carnitine 3-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + L-carnitine = NADH + H+ + 3-dehydrocarnitine.
2006-02-04 GO:0047053 (S)-cheilanthifoline synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + S-scoulerine = 2 H2O + NADP+ + S-cheilanthifoline.
2006-02-04 GO:0047052 (S)-stylopine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + S-cheilanthifoline = 2 H2O + NADP+ + S-stylopine.
2006-02-04 GO:0042188 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process Updated DEFINITION The breakdown into simpler components of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2006-02-04 GO:0018977 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process Updated DEFINITION The chemical reactions involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2006-02-04 GO:0018829 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity Updated DEFINITION Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
2006-02-04 GO:0018702 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity Updated DEFINITION Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
2006-02-04 GO:0018559 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.
2006-02-04 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.
2006-02-04 GO:0047159 1-alkenylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.
2006-02-04 GO:0004462 lactoylglutathione lyase activity Updated DEFINITION Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
2006-02-04 GO:0004464 leukotriene-C4 synthase activity Updated DEFINITION Catalysis of the reaction: leukotriene C4 = leukotriene A4 + glutathione.
2006-02-04 GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity Updated DEFINITION Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.
2006-02-04 GO:0050061 long-chain-aldehyde dehydrogenase activity Updated DEFINITION Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+.
2006-02-04 GO:0050637 lovastatin nonaketide synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + 8 malonyl-CoA + 11 NADPH + 11 H+ + S-adenosyl-L-methionine = dihydromonacolin L + 9 CoA + 8 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O.
2006-02-04 GO:0016851 magnesium chelatase activity Updated DEFINITION Catalysis of the reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+.
2006-02-04 GO:0004474 malate synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + glyoxylate = L-malate + CoA.
2006-02-04 GO:0018506 maleylacetate reductase activity Updated DEFINITION Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.
2006-02-04 GO:0050481 mandelate 4-monooxygenase activity Updated DEFINITION Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + O2 + (tetrahydrobiopterin/tetrahydropteridine) = (S)-4-hydroxymandelate + H2O + (dihydrobiopterin/dihydropteridine). (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.
2006-02-04 GO:0016689 manganese peroxidase activity Updated DEFINITION Catalysis of the reaction: 2 Mn2+ + 2 H+ + H2O2 = 2 Mn3+ + 2 H2O.
2006-02-04 GO:0015049 methane monooxygenase activity Updated DEFINITION Catalysis of the reaction: methane + NAD(P)H + O2 + H+ = methanol + NAD(P)+ + H2O.
2006-02-04 GO:0000317 methionine-S-oxide reductase activity Updated DEFINITION Catalysis of the reaction: L-methionine S-oxide + thioredoxin = L-methionine + thioredoxin disulfide. Thioredoxin disulfide is the oxidized form of thioredoxin. No reaction on oxidized methionine in peptide linkage.
2006-02-04 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity Updated DEFINITION Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
2006-02-04 GO:0047084 methyltetrahydroprotoberberine 14-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine.
2006-02-04 GO:0004484 mRNA guanylyltransferase activity Updated DEFINITION Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
2006-02-04 GO:0050111 mycocerosate synthase activity Updated DEFINITION Catalysis of the reaction: acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H+ = multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+.
2006-02-04 GO:0047157 myelin-proteolipid O-palmitoyltransferase activity Updated DEFINITION Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA.
2006-02-04 GO:0050564 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity Updated DEFINITION Catalysis of the reaction: L-2-aminohexanedioate + L-cysteine + L-valine + 3 ATP + H2O = N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate.
2006-02-04 GO:0050694 galactose 3-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.
2006-02-04 GO:0001733 galactosylceramide sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.
2006-02-04 GO:0047170 glucarate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: D-glucarate + sinapoyl-CoA = O-sinapoylglucarate + CoA.
2006-02-04 GO:0047171 glucarolactone O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.
2006-02-04 GO:0047140 glutathione-CoA-glutathione transhydrogenase activity Updated DEFINITION Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.
2006-02-04 GO:0047014 glycerol-3-phosphate 1-dehydrogenase [NADP+] activity Updated DEFINITION Catalysis of the reaction: NADP+ + glycerol-3-phosphate = NADPH + H+ + glyceraldehyde-3-phosphate.
2006-02-04 GO:0047396 glycosylphosphatidylinositol diacylglycerol-lyase activity Updated DEFINITION Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.
2006-02-04 GO:0003934 GTP cyclohydrolase I activity Updated DEFINITION Catalysis of the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
2006-02-04 GO:0004394 heparan sulfate 2-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.
2006-02-04 GO:0017095 heparan sulfate 6-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate.
2006-02-04 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2006-02-04 GO:0047017 prostaglandin-F synthase activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2006-02-04 GO:0047134 protein-disulfide reductase activity Updated DEFINITION Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
2006-02-04 GO:0000318 protein-methionine-R-oxide reductase activity Updated DEFINITION Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0008113 peptide-methionine (S)-S-oxide reductase activity Updated DEFINITION Catalysis of the reaction: protein L-methionine + thioredoxin disulfide = protein L-methionine S-oxide + thioredoxin.
2006-02-04 GO:0008476 protein-tyrosine sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
2006-02-04 GO:0004074 biliverdin reductase activity Updated DEFINITION Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
2006-02-04 GO:0018792 bis(4-chlorophenyl)acetate decarboxylase activity Updated DEFINITION Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.
2006-02-04 GO:0047135 bis-gamma-glutamylcystine reductase activity Updated DEFINITION Catalysis of the reaction: 2 gamma-glutamylcysteine + NADP+ = bis-gamma-glutamylcystine + NADPH + H+.
2006-02-04 GO:0047728 carnitine 3-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + L-carnitine = NADH + 3-dehydrocarnitine.
2006-02-04 GO:0051108 carnitine-CoA ligase activity Updated DEFINITION Catalysis of the reaction: D-carnitine + CoA = D-carnitinyl-CoA.
2006-02-04 GO:0051063 CDP reductase activity Updated DEFINITION Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.
2006-02-04 GO:0047193 CDP-acylglycerol O-arachidonoyltransferase activity Updated DEFINITION Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA.
2006-02-04 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
2006-02-04 GO:0019133 choline monooxygenase activity Updated DEFINITION Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.
2006-02-04 GO:0047754 choline sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + choline = adenosine 3',5'-bisphosphate + choline sulfate.
2006-02-04 GO:0047756 chondroitin 4-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.
2006-02-04 GO:0008459 chondroitin 6-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2006-02-04 GO:0004108 citrate (Si)-synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
2006-02-04 GO:0047036 codeinone reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NADP+ + codeine = NADPH + H+ + codeinone.
2006-02-04 GO:0050524 coenzyme-B sulfoethylthiotransferase activity Updated DEFINITION Catalysis of the reaction: 2-(methylthio)ethanesulfonate + N-(7-mercaptoheptanoyl)threonine 3-O-phosphate = CoM-S-S-CoB + methane. 2-(methylthio)ethanesulfonate is also known as methyl-CoM; N-(7-mercaptoheptanoyl)threonine 3-O-phosphate is also known as coenzyme B.
2006-02-04 GO:0047785 cortisol sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cortisol = adenosine 3',5'-bisphosphate + cortisol 21-sulfate.
2006-02-04 GO:0051109 crotonobetaine-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + crotono-betaine = crotonobetainyl-CoA.
2006-02-04 GO:0051065 CTP reductase activity Updated DEFINITION Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0047198 cysteine-S-conjugate N-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: an S-substituted L-cysteine + acetyl-CoA = an S-substituted N-acetyl-L-cysteine + CoA.
2006-02-04 GO:0008716 D-alanine-D-alanine ligase activity Updated DEFINITION Catalysis of the reaction: ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
2006-02-04 GO:0047038 D-arabinitol 2-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + D-arabitol = NADH + H+ + D-ribulose.
2006-02-04 GO:0047160 alkylglycerophosphate 2-O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.
2006-02-04 GO:0047685 amine sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.
2006-02-04 GO:0018978 anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process Updated DEFINITION The chemical reactions involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.
2006-02-04 GO:0047183 anthocyanin 5-aromatic acyltransferase activity Updated DEFINITION Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA.
2006-02-04 GO:0018618 anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity Updated DEFINITION Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3.
2006-02-04 GO:0030612 arsenate reductase (thioredoxin) activity Updated DEFINITION Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is NADPH -> thioredoxin reductase -> thioredoxin -> arsenate reductase.
2006-02-04 GO:0004062 aryl sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.
2006-02-04 GO:0003878 ATP citrate synthase activity Updated DEFINITION Catalysis of the reaction: ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
2006-02-04 GO:0047027 benzyl-2-methyl-hydroxybutyrate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + benzyl (2R,3S)-2-methyl-3-hydroxybutanoate = NADPH + H+ + benzyl 2-methyl-3-oxobutanoate.
2006-02-04 GO:0047054 berbamunine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + R-N-methylcoclaurine + S-N-methylcoclaurine = 2 H2O + NADP+ + berbamunine.
2006-02-04 GO:0047704 bile-salt sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.
2006-02-04 GO:0047104 hexadecanal dehydrogenase (acylating) activity Updated DEFINITION Catalysis of the reaction: NAD+ + CoA + palmitaldehyde = NADH + palmityl-CoA.
2006-02-04 GO:0004399 histidinol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.
2006-02-04 GO:0004410 homocitrate synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + 2-oxoglutarate = 2-hydroxybutane-1,2,4-tricarboxylate + CoA.
2006-02-04 GO:0047046 homoisocitrate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate.
2006-02-04 GO:0047010 hydroxycyclohexanecarboxylate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate = NADH + H+ + (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate.
2006-02-04 GO:0004421 hydroxymethylglutaryl-CoA synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.
2006-02-04 GO:0047085 hydroxyphenylacetonitrile 2-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + 4-hydroxyphenylacetonitrile = H2O + NADP+ + 4-hydroxymandelonitrile.
2006-02-04 GO:0047018 indole-3-acetaldehyde reductase (NADH) activity Updated DEFINITION Catalysis of the reaction: NAD+ + indole-3-ethanol = NADH + H+ + indole acetaldehyde.
2006-02-04 GO:0047019 indole-3-acetaldehyde reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NADP+ + indole-3-ethanol = NADPH + H+ + indole acetaldehyde.
2006-02-04 GO:0047168 isocitrate O-dihydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: threo-d(s)-iso-citrate + caffeoyl-CoA = 2-caffeoylisocitrate + CoA.
2006-02-04 GO:0047164 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity Updated DEFINITION Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.
2006-02-04 GO:0050010 isovitexin beta-glucosyltransferase activity Updated DEFINITION Catalysis of the reaction: UDP-glucose + isovitexin = isovitexin 2''-O-beta-D-glucoside + UDP.
2006-02-04 GO:0045130 keratan sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.
2006-02-04 GO:0047002 L-arabinitol 2-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + L-arabitol = NADH + H+ + L-ribulose.
2006-02-04 GO:0045431 flavonol synthase activity Updated DEFINITION Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.
2006-02-04 GO:0047165 flavonol-3-O-beta-glucoside O-malonyltransferase activity Updated DEFINITION Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA.
2006-02-04 GO:0008752 FMN reductase activity Updated DEFINITION Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+.
2006-02-04 GO:0047169 galactarate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: feruloyl-CoA + D-galactarate = O-feruloylgalactarate + CoA.
2006-02-04 GO:0047415 D-benzoylarginine-4-nitroanilide amidase activity Updated DEFINITION Catalysis of the reaction: H2O + N-benzoyl-D-arginine-4-nitroanilide = N-benzoyl-D-arginine + 4-nitroaniline.
2006-02-04 GO:0018688 DDT 2,3-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.
2006-02-04 GO:0018833 DDT-dehydrochlorinase activity Updated DEFINITION Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride.
2006-02-04 GO:0047153 deoxycytidylate 5-hydroxymethyltransferase activity Updated DEFINITION Catalysis of the reaction: 5,10-methylenetetrahydrofolate + H2O + deoxycytidylate = tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.
2006-02-04 GO:0050003 deoxycytidylate C-methyltransferase activity Updated DEFINITION Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = deoxy-5-methylcytidylate + 7,8-dihydrofolate.
2006-02-04 GO:0047364 desulfoglucosinolate sulfotransferase activity Updated DEFINITION Catalysis of the reaction: desulfoglucotropeolin + 3'-phosphoadenosine 5'-phosphosulfate = glucotropeolin + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047850 diaminopimelate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH.
2006-02-04 GO:0008838 diaminopropionate ammonia-lyase activity Updated DEFINITION Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3.
2006-02-04 GO:0047031 diethyl 2-methyl-3-oxosuccinate reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + diethyl (2R,3R)-2-methyl-3-hydroxysuccinate = NADPH + H+ + diethyl-2-methyl-3-oxosuccinate.
2006-02-04 GO:0047852 diferric-transferrin reductase activity Updated DEFINITION Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.
2006-02-04 GO:0047447 erythro-3-hydroxyaspartate ammonia-lyase activity Updated DEFINITION Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid.
2006-02-04 GO:0047879 erythronolide synthase activity Updated DEFINITION Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.
2006-02-04 GO:0004304 estrone sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.
2006-02-04 GO:0004312 fatty acid synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-02-04 GO:0030586 [methionine synthase] reductase activity Updated DEFINITION Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.
2006-02-04 GO:0047081 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NAD(P)H + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NAD(P)+ + 2-(acetamidomethylene)succinate.
2006-02-04 GO:0047048 3-hydroxybenzyl-alcohol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 3-hydroxybenzyl alcohol = NADPH + H+ + 3-hydroxybenzaldehyde.
2006-02-04 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity Updated DEFINITION Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].
2006-02-04 GO:0047136 4-(dimethylamino)phenylazoxybenzene reductase activity Updated DEFINITION Catalysis of the reaction: 4-dimethylaminophenylazobenzene + NADP+ = 4-(dimethylamino)phenylazoxybenzene + NADPH + H+.
2006-02-04 GO:0047162 17-O-deacetylvindoline O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: 17-O-deacetylvindoline + acetyl-CoA = vindoline + CoA.
2006-02-04 GO:0008666 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity Updated DEFINITION Catalysis of the reaction: succinyl-CoA + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate.
2006-02-04 GO:0047189 2,3-diaminopropionate N-oxalyltransferase activity Updated DEFINITION Catalysis of the reaction: L-2,3-diaminopropanoate + oxalyl-CoA = N3-oxalyl-L-23-diaminopropanoate + CoA.
2006-02-04 GO:0018542 2,3-dihydroxy DDT 1,2-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.
2006-02-04 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.
2006-02-04 GO:0047190 2-acylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.
2006-02-04 GO:0018626 2-chlorobenzoate 1,2-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.
2006-02-04 GO:0047000 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 2-dehydro-3-deoxy-D-gluconate = NADPH + H+ + (4S,5S)-4,5-dehydroxy-2,6-dioxohexanoate.
2006-02-04 GO:0050625 2-hydroxy-1,4-benzoquinone reductase activity Updated DEFINITION Catalysis of the reaction: hydroxybenzoquinone + NADH + H+ = 1,2,4-trihydroxybenzene + NAD+.
2006-02-04 GO:0019142 2-hydroxyglutarate synthase activity Updated DEFINITION Catalysis of the reaction: propanoyl-CoA + H2O + glyoxylate = 2-hydroxyglutarate + CoA.
2006-02-04 GO:0003852 2-isopropylmalate synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA.
2006-02-04 GO:0047101 2-oxoisovalerate dehydrogenase (acylating) activity Updated DEFINITION Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.
2006-02-04 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.
2006-02-04 GO:0047007 pregnan-21-ol dehydrogenase (NAD+) activity Updated DEFINITION Catalysis of the reaction: NAD+ + pregnan-21-ol = NADH + H+ + pregnan-21-al.
2006-02-04 GO:0047008 pregnan-21-ol dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + pregnan-21-ol = NADPH + H+ + pregnan-21-al.
2006-02-04 GO:0050428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process Updated DEFINITION The formation from simpler components of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
2006-02-04 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process Updated DEFINITION The chemical reactions involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
2006-02-04 GO:0047023 androsterone dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
2006-02-04 GO:0030283 testosterone dehydrogenase [NAD(P)] activity Updated DEFINITION Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.
2006-02-04 GO:0047163 3,4-dichloroaniline N-malonyltransferase activity Updated DEFINITION Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonate + CoA.
2006-02-04 GO:0047035 testosterone dehydrogenase (NAD+) activity Updated DEFINITION Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione.
2006-02-04 GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.
2006-02-04 GO:0047477 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA + pyrophosphate + AMP.
2006-02-04 GO:0047476 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + pyrophosphate + AMP.
2006-02-04 GO:0047009 3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.
2006-02-04 GO:0047043 3-alpha-hydroxycholanate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-cholanate = NADH + H+ + 3-oxo-5-beta-cholanate.
2006-02-04 GO:0047032 3-alpha-hydroxyglycyrrhetinate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 3-alpha-hydroxyglycyrrhetinate = NADPH + H+ + 3-oxoglycyrrhetinate.
2006-02-04 GO:0047026 androsterone dehydrogenase (A-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
2006-02-04 GO:0047042 androsterone dehydrogenase (B-specific) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
2006-02-04 GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 5-alpha-androstan-3-beta,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADPH + H+.
2006-02-04 GO:0046565 3-dehydroshikimate dehydratase activity Updated DEFINITION Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate (protocatechuate) + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.
2006-02-04 GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity Updated DEFINITION Catalysis of the reaction: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate.
2006-02-04 GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
2006-02-04 GO:0018497 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity Updated DEFINITION Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.
2006-02-04 GO:0047013 cholate 12-alpha dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate = NADPH + H+ + 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate.
2006-02-04 GO:0047203 13-hydroxylupinine O-tigloyltransferase activity Updated DEFINITION Catalysis of the reaction: 13-hydroxylupinine + (E)-2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyl)oxylupinine + CoA.
2006-02-04 GO:0047034 15-hydroxyicosatetraenoate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.
2006-02-04 GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate = NADPH + H+ + (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate.
2006-02-04 GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.
2006-02-04 GO:0047033 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-dienoate.
2006-02-04 GO:0047005 16-alpha-hydroxysteroid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.
2006-02-04 GO:0018622 4-chlorophenylacetate 3,4-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 4-chlorophenyl acetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+.
2006-02-04 GO:0047030 4-hydroxycyclohexanecarboxylate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 4-hydroxycyclohexanecarboxylate = NADH + H+ + 4-oxocyclohexanecarboxylate.
2006-02-04 GO:0047106 4-hydroxyphenylacetaldehyde dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate.
2006-02-04 GO:0047083 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate.
2006-02-04 GO:0018770 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity Updated DEFINITION Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate + H2O = 2-(4-chlorophenyl)-3,3-dichloropropenoate.
2006-02-04 GO:0047028 6-pyruvoyltetrahydropterin 2'-reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.
2006-02-04 GO:0047022 7-beta-hydroxysteroid dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + 7-beta-hydroxysteroid = NADPH + H+ + 7-oxosteroid.
2006-02-04 GO:0003984 acetolactate synthase activity Updated DEFINITION Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.
2006-02-04 GO:0018710 acetone carboxylase activity Updated DEFINITION Catalysis of the reaction: acetone + ATP + 2 H2O + CO2 = AMP + 2 phosphate + acetoacetate.
2006-02-04 GO:0004017 adenylate kinase activity Updated DEFINITION Catalysis of the reaction: ATP + AMP = 2 ADP.
2006-02-04 GO:0004020 adenylylsulfate kinase activity Updated DEFINITION Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
2006-02-04 GO:0051061 ADP reductase activity Updated DEFINITION Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.
2006-02-04 GO:0047380 ADP-dependent medium-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + acyl-CoA = an acid + CoA.
2006-02-04 GO:0047379 ADP-dependent short-chain-acyl-CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: H2O + acyl-CoA = an acid + CoA.
2006-02-04 GO:0004027 alcohol sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
2006-02-04 GO:0008726 alkanesulfonate monooxygenase activity Updated DEFINITION Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + SO3(2-) (sulfite) + H2O + FMN.
2006-02-04 GO:0050698 proteoglycan sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.
2006-02-04 GO:0050226 psychosine sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate.
2006-02-04 GO:0047040 pteridine reductase activity Updated DEFINITION Catalysis of the reaction: 2 NADP+ + tetra-hydro-biopterin = 2 NADPH + 2 H+ + biopterin.
2006-02-04 GO:0047174 putrescine N-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: putrescine + caffeoyl-CoA = N-caffeoylputrescine + CoA.
2006-02-04 GO:0047367 quercetin-3,3'-bissulfate 7-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047365 quercetin-3-sulfate 3'-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: quercetin 3-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3'-bissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047366 quercetin-3-sulfate 4'-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: quercetin 3-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,4'-bissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047205 quinate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.
2006-02-04 GO:0050249 Renilla-luciferin sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + Renilla luciferin = adenosine 3',5'-bisphosphate + luciferyl sulfate.
2006-02-04 GO:0017051 retinol dehydratase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.
2006-02-04 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Updated DEFINITION Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0008998 ribonucleoside-triphosphate reductase activity Updated DEFINITION Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.
2006-02-04 GO:0016984 ribulose-bisphosphate carboxylase activity Updated DEFINITION Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate.
2006-02-04 GO:0047037 salutaridine reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NADP+ + salutaridinol = NADPH + H+ + salutaridine.
2006-02-04 GO:0047055 salutaridine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + (R)-reticuline = 2 H2O + NADP+ + salutaridine.
2006-02-04 GO:0047077 Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity Updated DEFINITION Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + pyrophosphate + AMP + CO2 + oxidized Photinus luciferin.
2006-02-04 GO:0018620 phthalate 4,5-dioxygenase activity Updated DEFINITION Catalysis of the reaction: phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+.
2006-02-04 GO:0047166 1-alkenylglycerophosphoethanolamine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.
2006-02-04 GO:0047167 1-alkyl-2-acetylglycerol O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.
2006-02-04 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.
2006-02-04 GO:0047191 1-alkylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA.
2006-02-04 GO:0018827 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity Updated DEFINITION Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.
2006-02-04 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.
2006-02-04 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine 4-sulfate (in chondroitin sulfate) = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4,6-bissulfate. Functions on nonreducing terminal and internal GalNAc(4SO(4)) residues contained in chondroitin sulfate A and dermatan sulfate (chondroitin sulfate B).
2006-02-04 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.
2006-02-04 GO:0047185 N-acetylneuraminate 4-O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.
2006-02-04 GO:0047186 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.
2006-02-04 GO:0047444 N-acylneuraminate-9-phosphate synthase activity Updated DEFINITION Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.
2006-02-04 GO:0047137 N-hydroxy-2-acetamidofluorene reductase activity Updated DEFINITION Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+.
2006-02-04 GO:0003958 NADPH-hemoprotein reductase activity Updated DEFINITION Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.
2006-02-04 GO:0050140 nitrate reductase (cytochrome) activity Updated DEFINITION Catalysis of the reaction: ferrocytochrome + NO3- (nitrate) = ferricytochrome + NO2- (nitrite).
2006-02-04 GO:0009703 nitrate reductase (NADH) activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + NAD+ + H2O = NO3- (nitrate) + NADH + H+.
2006-02-04 GO:0050464 nitrate reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + NADP+ + H2O = NO3- (nitrate) + NADPH + H+.
2006-02-04 GO:0047180 salutaridinol 7-O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: salutaridinol + acetyl-CoA = 7-O-acetylsalutaridinol + CoA.
2006-02-04 GO:0047172 shikimate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.
2006-02-04 GO:0004768 stearoyl-CoA 9-desaturase activity Updated DEFINITION Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O.
2006-02-04 GO:0050294 steroid sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate.
2006-02-04 GO:0047012 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one.
2006-02-04 GO:0008146 sulfotransferase activity Updated DEFINITION Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.
2006-02-04 GO:0047161 tartronate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: 2-hydroxymalonate + sinapoyl-CoA = sinapoyltartronate + CoA.
2006-02-04 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity Updated DEFINITION Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.
2006-02-04 GO:0047200 tetrahydrodipicolinate N-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: L-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA = L-2-acetamido-6-oxoheptanedioate + CoA.
2006-02-04 GO:0030269 tetrahydromethanopterin S-methyltransferase activity Updated DEFINITION Catalysis of the reaction: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate. 2-(methylthio)ethanesulfonate is also known as methyl-CoM.
2006-02-04 GO:0047039 tetrahydroxynaphthalene reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.
2006-02-04 GO:0018760 thiocyanate hydrolase activity Updated DEFINITION Catalysis of the reaction: thiocyanate + H2O = NH3 + carbonyl sulfide.
2006-02-04 GO:0009031 thiol peroxidase activity Updated DEFINITION Catalysis of the reaction: thioredoxin + H2O2 = thioredoxin disulfide + H2O.
2006-02-04 GO:0050603 thiophene-2-carbonyl-CoA monooxygenase activity Updated DEFINITION Catalysis of the reaction: thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O.
2006-02-04 GO:0008379 thioredoxin peroxidase activity Updated DEFINITION Catalysis of the reaction: thioredoxin + H2O2 = thioredoxin disulfide + H2O.
2006-02-04 GO:0050797 thymidylate synthase (FAD) activity Updated DEFINITION Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + FADH2 = dTMP + tetrahydrofolate + FAD.
2006-02-04 GO:0004800 thyroxine 5'-deiodinase activity Updated DEFINITION Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
2006-02-04 GO:0047062 trans-acenaphthene-1,2-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + (+-)-trans-acenaphthene-1,2-diol = NADPH + H+ + acenaphthenequinone.
2006-02-04 GO:0030133 transport vesicle Updated DEFINITION Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, and to destinations within or outside the cell.
2006-02-04 GO:0047363 triglucosylalkylacylglycerol sulfotransferase activity Updated DEFINITION Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0015042 trypanothione-disulfide reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.
2006-02-04 GO:0004510 tryptophan 5-monooxygenase activity Updated DEFINITION Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
2006-02-04 GO:0051064 TTP reductase activity Updated DEFINITION Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0004511 tyrosine 3-monooxygenase activity Updated DEFINITION Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
2006-02-04 GO:0017067 tyrosine-ester sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate.
2006-02-04 GO:0051062 UDP reductase activity Updated DEFINITION Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.
2006-02-04 GO:0047368 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity Updated DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine 4-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = UDP-N-acetyl-D-galactosamine 4,6-bissulfate + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047004 UDP-N-acetylglucosamine 6-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: H2O + 2 NAD+ + UDP-N-acetyl-D-glucosamine = 2 NADH + 2 H+ + UDP-N-acetyl-2-amino-d-glucuronate.
2006-02-04 GO:0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity Updated DEFINITION Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
2006-02-04 GO:0018487 vanillate O-demethylase (anaerobic) activity Updated DEFINITION Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.
2006-02-04 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-desulfoheparin = adenosine 3',5'-bisphosphate + heparin.
2006-02-04 GO:0047889 ferredoxin-nitrate reductase activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + H2O + 2 oxidized ferredoxin = NO3- (nitrate) + 2 reduced ferredoxin.
2006-02-04 GO:0048307 ferredoxin-nitrite reductase activity Updated DEFINITION Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = NO2(-) (nitrite) + 6 reduced ferredoxin + 7 H+.
2006-02-04 GO:0000293 ferric-chelate reductase activity Updated DEFINITION Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+.
2006-02-04 GO:0047894 flavonol 3-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + quercetin = adenosine 3',5'-bisphosphate + quercetin 3-sulfate.
2006-02-04 GO:0008940 nitrate reductase activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + acceptor = NO3- (nitrate) + reduced acceptor.
2006-02-04 GO:0050463 nitrate reductase [NAD(P)H] activity Updated DEFINITION Catalysis of the reaction: NO2- (nitrite) + NAD(P)+ + H2O = NO3- (nitrate) + NAD(P)H + H+.
2006-02-04 GO:0008941 nitric oxide dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 NO3- + NADP+.
2006-02-04 GO:0047047 oxaloglycolate reductase (decarboxylating) activity Updated DEFINITION Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate.
2006-02-04 GO:0018548 pentaerythritol trinitrate reductase activity Updated DEFINITION Catalysis of the reaction: pentaerythritol tri(or tetra)nitrate + NADPH = NADP+ + NO3- (nitrate) + pentaerythritol di(or tri)nitrate.
2006-02-04 GO:0008955 peptidoglycan glycosyltransferase activity Updated DEFINITION Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.
2006-02-04 GO:0047475 phenylacetate-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + phenylacetate + ATP = phenylacetyl-CoA + products of ATP breakdown.
2006-02-04 GO:0004505 phenylalanine 4-monooxygenase activity Updated DEFINITION Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
2006-02-04 GO:0047110 phenylglyoxylate dehydrogenase (acylating) activity Updated DEFINITION Catalysis of the reaction: CoA + NAD+ + phenylglyoxylate = NADH + CO2 + benzoyl-S-CoA.
2006-02-04 GO:0004604 phosphoadenylyl-sulfate reductase (thioredoxin) activity Updated DEFINITION Catalysis of the reaction: adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenosine 5'-phosphosulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
2006-02-04 GO:0050186 phosphoadenylylsulfatase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + SO4(2-) (sulfate).
2006-02-04 GO:0004689 phosphorylase kinase activity Updated DEFINITION Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.
2006-02-04 GO:0047049 (R)-2-hydroxy-fatty acid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + R-2-hydroxystearate = NADH + H+ + 2-oxostearate.
2006-02-04 GO:0047029 (R)-4-hydroxyphenyllactate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + H+ + 3-(4-hydroxyphenyl)pyruvate.
2006-02-04 GO:0047050 (S)-2-hydroxy-fatty acid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + (S)-2-hydroxystearate = NADH + H+ + 2-oxostearate.
2006-02-04 GO:0047056 (S)-canadine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + S-tetrahydrocolumbamine = 2 H2O + NADP+ + S-canadine.
2006-02-04 GO:0047041 (S)-carnitine 3-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + L-carnitine = NADH + H+ + 3-dehydrocarnitine.
2006-02-04 GO:0047053 (S)-cheilanthifoline synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + S-scoulerine = 2 H2O + NADP+ + S-cheilanthifoline.
2006-02-04 GO:0047052 (S)-stylopine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + S-cheilanthifoline = 2 H2O + NADP+ + S-stylopine.
2006-02-04 GO:0042188 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process Updated DEFINITION The breakdown into simpler components of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2006-02-04 GO:0018977 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process Updated DEFINITION The chemical reactions involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2006-02-04 GO:0018829 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity Updated DEFINITION Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
2006-02-04 GO:0018702 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity Updated DEFINITION Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
2006-02-04 GO:0018559 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.
2006-02-04 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.
2006-02-04 GO:0047159 1-alkenylglycerophosphocholine O-acyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.
2006-02-04 GO:0004462 lactoylglutathione lyase activity Updated DEFINITION Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
2006-02-04 GO:0004464 leukotriene-C4 synthase activity Updated DEFINITION Catalysis of the reaction: leukotriene C4 = leukotriene A4 + glutathione.
2006-02-04 GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity Updated DEFINITION Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.
2006-02-04 GO:0050061 long-chain-aldehyde dehydrogenase activity Updated DEFINITION Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+.
2006-02-04 GO:0050637 lovastatin nonaketide synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + 8 malonyl-CoA + 11 NADPH + 11 H+ + S-adenosyl-L-methionine = dihydromonacolin L + 9 CoA + 8 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O.
2006-02-04 GO:0016851 magnesium chelatase activity Updated DEFINITION Catalysis of the reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+.
2006-02-04 GO:0004474 malate synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + glyoxylate = L-malate + CoA.
2006-02-04 GO:0018506 maleylacetate reductase activity Updated DEFINITION Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.
2006-02-04 GO:0050481 mandelate 4-monooxygenase activity Updated DEFINITION Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + O2 + (tetrahydrobiopterin/tetrahydropteridine) = (S)-4-hydroxymandelate + H2O + (dihydrobiopterin/dihydropteridine). (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.
2006-02-04 GO:0016689 manganese peroxidase activity Updated DEFINITION Catalysis of the reaction: 2 Mn2+ + 2 H+ + H2O2 = 2 Mn3+ + 2 H2O.
2006-02-04 GO:0015049 methane monooxygenase activity Updated DEFINITION Catalysis of the reaction: methane + NAD(P)H + O2 + H+ = methanol + NAD(P)+ + H2O.
2006-02-04 GO:0000317 methionine-S-oxide reductase activity Updated DEFINITION Catalysis of the reaction: L-methionine S-oxide + thioredoxin = L-methionine + thioredoxin disulfide. Thioredoxin disulfide is the oxidized form of thioredoxin. No reaction on oxidized methionine in peptide linkage.
2006-02-04 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity Updated DEFINITION Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
2006-02-04 GO:0047084 methyltetrahydroprotoberberine 14-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine.
2006-02-04 GO:0004484 mRNA guanylyltransferase activity Updated DEFINITION Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
2006-02-04 GO:0050111 mycocerosate synthase activity Updated DEFINITION Catalysis of the reaction: acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H+ = multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+.
2006-02-04 GO:0047157 myelin-proteolipid O-palmitoyltransferase activity Updated DEFINITION Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA.
2006-02-04 GO:0050564 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity Updated DEFINITION Catalysis of the reaction: L-2-aminohexanedioate + L-cysteine + L-valine + 3 ATP + H2O = N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate.
2006-02-04 GO:0050694 galactose 3-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.
2006-02-04 GO:0001733 galactosylceramide sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.
2006-02-04 GO:0047170 glucarate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: D-glucarate + sinapoyl-CoA = O-sinapoylglucarate + CoA.
2006-02-04 GO:0047171 glucarolactone O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.
2006-02-04 GO:0047140 glutathione-CoA-glutathione transhydrogenase activity Updated DEFINITION Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.
2006-02-04 GO:0047014 glycerol-3-phosphate 1-dehydrogenase [NADP+] activity Updated DEFINITION Catalysis of the reaction: NADP+ + glycerol-3-phosphate = NADPH + H+ + glyceraldehyde-3-phosphate.
2006-02-04 GO:0047396 glycosylphosphatidylinositol diacylglycerol-lyase activity Updated DEFINITION Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.
2006-02-04 GO:0003934 GTP cyclohydrolase I activity Updated DEFINITION Catalysis of the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
2006-02-04 GO:0004394 heparan sulfate 2-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.
2006-02-04 GO:0017095 heparan sulfate 6-O-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate.
2006-02-04 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin-glucosamine 3-O-sulfate.
2006-02-04 GO:0047017 prostaglandin-F synthase activity Updated DEFINITION Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
2006-02-04 GO:0047134 protein-disulfide reductase activity Updated DEFINITION Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
2006-02-04 GO:0000318 protein-methionine-R-oxide reductase activity Updated DEFINITION Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0008113 peptide-methionine (S)-S-oxide reductase activity Updated DEFINITION Catalysis of the reaction: protein L-methionine + thioredoxin disulfide = protein L-methionine S-oxide + thioredoxin.
2006-02-04 GO:0008476 protein-tyrosine sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
2006-02-04 GO:0004074 biliverdin reductase activity Updated DEFINITION Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
2006-02-04 GO:0018792 bis(4-chlorophenyl)acetate decarboxylase activity Updated DEFINITION Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.
2006-02-04 GO:0047135 bis-gamma-glutamylcystine reductase activity Updated DEFINITION Catalysis of the reaction: 2 gamma-glutamylcysteine + NADP+ = bis-gamma-glutamylcystine + NADPH + H+.
2006-02-04 GO:0047728 carnitine 3-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + L-carnitine = NADH + 3-dehydrocarnitine.
2006-02-04 GO:0051108 carnitine-CoA ligase activity Updated DEFINITION Catalysis of the reaction: D-carnitine + CoA = D-carnitinyl-CoA.
2006-02-04 GO:0051063 CDP reductase activity Updated DEFINITION Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.
2006-02-04 GO:0047193 CDP-acylglycerol O-arachidonoyltransferase activity Updated DEFINITION Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA.
2006-02-04 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
2006-02-04 GO:0019133 choline monooxygenase activity Updated DEFINITION Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.
2006-02-04 GO:0047754 choline sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + choline = adenosine 3',5'-bisphosphate + choline sulfate.
2006-02-04 GO:0047756 chondroitin 4-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.
2006-02-04 GO:0008459 chondroitin 6-sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
2006-02-04 GO:0004108 citrate (Si)-synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
2006-02-04 GO:0047036 codeinone reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NADP+ + codeine = NADPH + H+ + codeinone.
2006-02-04 GO:0050524 coenzyme-B sulfoethylthiotransferase activity Updated DEFINITION Catalysis of the reaction: 2-(methylthio)ethanesulfonate + N-(7-mercaptoheptanoyl)threonine 3-O-phosphate = CoM-S-S-CoB + methane. 2-(methylthio)ethanesulfonate is also known as methyl-CoM; N-(7-mercaptoheptanoyl)threonine 3-O-phosphate is also known as coenzyme B.
2006-02-04 GO:0047785 cortisol sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cortisol = adenosine 3',5'-bisphosphate + cortisol 21-sulfate.
2006-02-04 GO:0051109 crotonobetaine-CoA ligase activity Updated DEFINITION Catalysis of the reaction: CoA + crotono-betaine = crotonobetainyl-CoA.
2006-02-04 GO:0051065 CTP reductase activity Updated DEFINITION Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
2006-02-04 GO:0047198 cysteine-S-conjugate N-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: an S-substituted L-cysteine + acetyl-CoA = an S-substituted N-acetyl-L-cysteine + CoA.
2006-02-04 GO:0008716 D-alanine-D-alanine ligase activity Updated DEFINITION Catalysis of the reaction: ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
2006-02-04 GO:0047038 D-arabinitol 2-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + D-arabitol = NADH + H+ + D-ribulose.
2006-02-04 GO:0047160 alkylglycerophosphate 2-O-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.
2006-02-04 GO:0047685 amine sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.
2006-02-04 GO:0018978 anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process Updated DEFINITION The chemical reactions involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.
2006-02-04 GO:0047183 anthocyanin 5-aromatic acyltransferase activity Updated DEFINITION Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA.
2006-02-04 GO:0018618 anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity Updated DEFINITION Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3.
2006-02-04 GO:0030612 arsenate reductase (thioredoxin) activity Updated DEFINITION Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is NADPH -> thioredoxin reductase -> thioredoxin -> arsenate reductase.
2006-02-04 GO:0004062 aryl sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.
2006-02-04 GO:0003878 ATP citrate synthase activity Updated DEFINITION Catalysis of the reaction: ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
2006-02-04 GO:0047027 benzyl-2-methyl-hydroxybutyrate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NADP+ + benzyl (2R,3S)-2-methyl-3-hydroxybutanoate = NADPH + H+ + benzyl 2-methyl-3-oxobutanoate.
2006-02-04 GO:0047054 berbamunine synthase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + R-N-methylcoclaurine + S-N-methylcoclaurine = 2 H2O + NADP+ + berbamunine.
2006-02-04 GO:0047704 bile-salt sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.
2006-02-04 GO:0047104 hexadecanal dehydrogenase (acylating) activity Updated DEFINITION Catalysis of the reaction: NAD+ + CoA + palmitaldehyde = NADH + palmityl-CoA.
2006-02-04 GO:0004399 histidinol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.
2006-02-04 GO:0004410 homocitrate synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + 2-oxoglutarate = 2-hydroxybutane-1,2,4-tricarboxylate + CoA.
2006-02-04 GO:0047046 homoisocitrate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate.
2006-02-04 GO:0047010 hydroxycyclohexanecarboxylate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate = NADH + H+ + (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate.
2006-02-04 GO:0004421 hydroxymethylglutaryl-CoA synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + H2O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.
2006-02-04 GO:0047085 hydroxyphenylacetonitrile 2-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + 4-hydroxyphenylacetonitrile = H2O + NADP+ + 4-hydroxymandelonitrile.
2006-02-04 GO:0047018 indole-3-acetaldehyde reductase (NADH) activity Updated DEFINITION Catalysis of the reaction: NAD+ + indole-3-ethanol = NADH + H+ + indole acetaldehyde.
2006-02-04 GO:0047019 indole-3-acetaldehyde reductase (NADPH) activity Updated DEFINITION Catalysis of the reaction: NADP+ + indole-3-ethanol = NADPH + H+ + indole acetaldehyde.
2006-02-04 GO:0047168 isocitrate O-dihydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: threo-d(s)-iso-citrate + caffeoyl-CoA = 2-caffeoylisocitrate + CoA.
2006-02-04 GO:0047164 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity Updated DEFINITION Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.
2006-02-04 GO:0050010 isovitexin beta-glucosyltransferase activity Updated DEFINITION Catalysis of the reaction: UDP-glucose + isovitexin = isovitexin 2''-O-beta-D-glucoside + UDP.
2006-02-04 GO:0045130 keratan sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.
2006-02-04 GO:0047002 L-arabinitol 2-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: NAD+ + L-arabitol = NADH + H+ + L-ribulose.
2006-02-04 GO:0045431 flavonol synthase activity Updated DEFINITION Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.
2006-02-04 GO:0047165 flavonol-3-O-beta-glucoside O-malonyltransferase activity Updated DEFINITION Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA.
2006-02-04 GO:0008752 FMN reductase activity Updated DEFINITION Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+.
2006-02-04 GO:0047169 galactarate O-hydroxycinnamoyltransferase activity Updated DEFINITION Catalysis of the reaction: feruloyl-CoA + D-galactarate = O-feruloylgalactarate + CoA.
2006-02-04 GO:0047415 D-benzoylarginine-4-nitroanilide amidase activity Updated DEFINITION Catalysis of the reaction: H2O + N-benzoyl-D-arginine-4-nitroanilide = N-benzoyl-D-arginine + 4-nitroaniline.
2006-02-04 GO:0018688 DDT 2,3-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.
2006-02-04 GO:0018833 DDT-dehydrochlorinase activity Updated DEFINITION Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride.
2006-02-04 GO:0047153 deoxycytidylate 5-hydroxymethyltransferase activity Updated DEFINITION Catalysis of the reaction: 5,10-methylenetetrahydrofolate + H2O + deoxycytidylate = tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.
2006-02-04 GO:0050003 deoxycytidylate C-methyltransferase activity Updated DEFINITION Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = deoxy-5-methylcytidylate + 7,8-dihydrofolate.
2006-02-04 GO:0047364 desulfoglucosinolate sulfotransferase activity Updated DEFINITION Catalysis of the reaction: desulfoglucotropeolin + 3'-phosphoadenosine 5'-phosphosulfate = glucotropeolin + adenosine 3',5'-bisphosphate.
2006-02-04 GO:0047850 diaminopimelate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH.
2006-02-04 GO:0008838 diaminopropionate ammonia-lyase activity Updated DEFINITION Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3.
2006-02-04 GO:0047031 diethyl 2-methyl-3-oxosuccinate reductase activity Updated DEFINITION Catalysis of the reaction: NADP+ + diethyl (2R,3R)-2-methyl-3-hydroxysuccinate = NADPH + H+ + diethyl-2-methyl-3-oxosuccinate.
2006-02-04 GO:0047852 diferric-transferrin reductase activity Updated DEFINITION Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.
2006-02-04 GO:0047447 erythro-3-hydroxyaspartate ammonia-lyase activity Updated DEFINITION Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid.
2006-02-04 GO:0047879 erythronolide synthase activity Updated DEFINITION Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.
2006-02-04 GO:0004304 estrone sulfotransferase activity Updated DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.
2006-02-04 GO:0004312 fatty acid synthase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
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