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GO Term History: Displaying 61 audit records for all terms for the date 2006-01-26

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-01-26 GO:0018276 isopeptide cross-linking via N6-glycyl-L-lysine Updated DEFINITION The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.
2006-01-26 GO:0000277 [cytochrome c]-lysine N-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.
2006-01-26 GO:0050589 leucocyanidin oxygenase activity Updated DEFINITION Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.
2006-01-26 GO:0004184 lysine carboxypeptidase activity Updated DEFINITION Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma.
2006-01-26 GO:0008472 metallocarboxypeptidase D activity Updated DEFINITION Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid.
2006-01-26 GO:0047151 methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity Updated DEFINITION Catalysis of the reaction: FADH + H+ + tRNA U(psi)C = FAD+ + tRNA T(psi)C + THF.
2006-01-26 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA; m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.
2006-01-26 GO:0004484 mRNA guanylyltransferase activity Updated DEFINITION Catalysis of the reaction: GTP + (5')PP-pur-mRNA = diphosphate + G(5')PPP-pur-mRNA; G(5')PPP-pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
2006-01-26 GO:0050111 mycocerosate synthase activity Updated DEFINITION Catalysis of the reaction: acyl-CoA + n methylmalonyl-CoA + 2n NADPH+ + 2n H+ = multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+.
2006-01-26 GO:0047137 N-hydroxy-2-acetamidofluorene reductase activity Updated DEFINITION Catalysis of the reaction: N-hydroxy-2-acetamidofluorene + NAD(P)H + H+ = 2-acetamidofluorene + NAD(P)+.
2006-01-26 GO:0008941 nitric oxide dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 NO3- + 2 H+ + NADP+.
2006-01-26 GO:0005948 acetolactate synthase complex Updated DEFINITION A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.
2006-01-26 GO:0000062 fatty-acyl-CoA binding Updated DEFINITION Interacting selectively with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.
2006-01-26 GO:0046949 fatty-acyl-CoA biosynthetic process Updated DEFINITION The formation from simpler components of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
2006-01-26 GO:0006637 acyl-CoA metabolic process Updated DEFINITION The chemical reactions involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
2006-01-26 GO:0005541 acyl-CoA or acyl binding Updated DEFINITION OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid.
2006-01-26 GO:0008415 acyltransferase activity Updated DEFINITION Catalysis of the generalized reaction: acyl-carrier + reactant = acyl-reactant + carrier.
2006-01-26 GO:0008726 alkanesulfonate monooxygenase activity Updated DEFINITION Catalysis of the reaction: an alkanesulfonate + O2 + FMNH + H+ = an aldehyde + SO3(2-) (sulfite) + H2O + FMN+.
2006-01-26 GO:0009321 alkyl hydroperoxide reductase complex Updated DEFINITION An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.
2006-01-26 GO:0046353 aminoglycoside 3-N-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N3'-acetyl-2-deoxystreptamine antibiotic.
2006-01-26 GO:0018673 anthraniloyl-CoA monooxygenase activity Updated DEFINITION Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.
2006-01-26 GO:0019778 Atg12 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0019779 Atg8 activating enzyme Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0050473 arachidonate 15-lipoxygenase activity Updated DEFINITION Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
2006-01-26 GO:0004517 nitric-oxide synthase activity Updated DEFINITION Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
2006-01-26 GO:0046409 p-coumarate 3-hydroxylase activity Updated DEFINITION Catalysis of the 3-hydroxylation reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H20 + NADP+.
2006-01-26 GO:0046777 protein autophosphorylation Updated DEFINITION The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
2006-01-26 GO:0047134 protein-disulfide reductase activity Updated DEFINITION Catalysis of the reaction: protein-disulfide + NAD(P)H + H+ = protein-dithiol + NAD(P)+.
2006-01-26 GO:0008983 protein-glutamate O-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.
2006-01-26 GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester; this reaction is the methylation of peptidyl-L-leucine to form peptidyl-L-leucine methyl ester.
2006-01-26 GO:0016852 sirohydrochlorin cobaltochelatase activity Updated DEFINITION Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.
2006-01-26 GO:0008641 small protein activating enzyme activity Updated DEFINITION Catalysis of the activation of small proteins, such as ubiquitin, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0019948 SUMO activating enzyme activity Updated DEFINITION Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0031299 taurine-pyruvate aminotransferase activity Updated DEFINITION Catalysis of the reaction: taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde.
2006-01-26 GO:0004839 ubiquitin activating enzyme activity Updated DEFINITION Catalysis of the activation of the C-terminal carboxyl group of ubiquitin by the formation of a high-energy thiolester bond in an ATP-dependent manner.
2006-01-26 GO:0008642 ubiquitin-like activating enzyme activity Updated DEFINITION Catalysis of the activation of any small protein similar to ubiquitin, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0042292 URM1 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0047517 1,4-beta-D-xylan synthase activity Updated DEFINITION Catalysis of the reaction: UDP-D-xylose + 1,4-beta-D-xylan(n) = UDP + 1,4-beta-D-xylan(n+1).
2006-01-26 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex Updated DEFINITION An enzyme complex composed of two catalytic subunits, alpha1 and alpha2, which form a catalytic dimer, and a non-catalytic, regulatory subunit, beta. Modulates the action of platelet-activating factor (PAF).
2006-01-26 GO:0047011 2-dehydropantolactone reductase (A-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
2006-01-26 GO:0019141 2-dehydropantolactone reductase (B-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
2006-01-26 GO:0047082 3,9-dihydroxypterocarpan 6a-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + (6aR,11aR)-3,9-dihydroxypterocarpan = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.
2006-01-26 GO:0009316 3-isopropylmalate dehydratase complex Updated DEFINITION A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
2006-01-26 GO:0009334 3-phenylpropionate dioxygenase complex Updated DEFINITION Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol).
2006-01-26 GO:0047136 4-(dimethylamino)phenylazoxybenzene reductase activity Updated DEFINITION Catalysis of the reaction: 4-(dimethylamino)phenylazoxybenzene + NADPH + H+ = 4-dimethylaminophenylazobenzene + NADP+.
2006-01-26 GO:0047592 5-pyridoxate dioxygenase activity Updated DEFINITION Catalysis of the reaction: 3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + H+ + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+.
2006-01-26 GO:0047135 bis-gamma-glutamylcystine reductase activity Updated DEFINITION Catalysis of the reaction: bis-gamma-glutamylcystine + NADPH + H+ = 2 gamma-glutamylcysteine + NADP+.
2006-01-26 GO:0004183 carboxypeptidase E activity Updated DEFINITION Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents.
2006-01-26 GO:0018609 chlorobenzene dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).
2006-01-26 GO:0004109 coproporphyrinogen oxidase activity Updated DEFINITION Catalysis of the reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O.
2006-01-26 GO:0051267 CP2 mannose-ethanolamine phosphotransferase activity Updated DEFINITION Catalysis of the reaction: ethanolamine phosphate (EtN-P) + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.
2006-01-26 GO:0045441 deacetoxycephalosporin C synthetase activity Updated DEFINITION Catalysis of the formation of deacetoxycephalosporin from penicillin-N.
2006-01-26 GO:0019780 FAT10 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0046424 ferulate 5-hydroxylase activity Updated DEFINITION Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+.
2006-01-26 GO:0008752 FMN reductase activity Updated DEFINITION Catalysis of the reaction: FMNH + H+ + NAD(P)+ = FMN+ + NAD(P)H + H+.
2006-01-26 GO:0008883 glutamyl-tRNA reductase activity Updated DEFINITION Catalysis of the reaction: L-glutamate 1-semialdehyde + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + NADPH + H+.
2006-01-26 GO:0042293 Hub1 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0050501 hyaluronan synthase activity Updated DEFINITION Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)](n) + 2n UDP.
2006-01-26 GO:0019782 ISG15 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0045439 isopenicillin-N epimerase activity Updated DEFINITION Catalysis of the reaction: isopenicillin-N = penicillin-N.
2006-01-26 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity Updated DEFINITION Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-01-26 GO:0018276 isopeptide cross-linking via N6-glycyl-L-lysine Updated DEFINITION The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.
2006-01-26 GO:0000277 [cytochrome c]-lysine N-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.
2006-01-26 GO:0050589 leucocyanidin oxygenase activity Updated DEFINITION Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.
2006-01-26 GO:0004184 lysine carboxypeptidase activity Updated DEFINITION Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma.
2006-01-26 GO:0008472 metallocarboxypeptidase D activity Updated DEFINITION Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid.
2006-01-26 GO:0047151 methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity Updated DEFINITION Catalysis of the reaction: FADH + H+ + tRNA U(psi)C = FAD+ + tRNA T(psi)C + THF.
2006-01-26 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA; m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.
2006-01-26 GO:0004484 mRNA guanylyltransferase activity Updated DEFINITION Catalysis of the reaction: GTP + (5')PP-pur-mRNA = diphosphate + G(5')PPP-pur-mRNA; G(5')PPP-pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
2006-01-26 GO:0050111 mycocerosate synthase activity Updated DEFINITION Catalysis of the reaction: acyl-CoA + n methylmalonyl-CoA + 2n NADPH+ + 2n H+ = multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+.
2006-01-26 GO:0047137 N-hydroxy-2-acetamidofluorene reductase activity Updated DEFINITION Catalysis of the reaction: N-hydroxy-2-acetamidofluorene + NAD(P)H + H+ = 2-acetamidofluorene + NAD(P)+.
2006-01-26 GO:0008941 nitric oxide dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 NO3- + 2 H+ + NADP+.
2006-01-26 GO:0005948 acetolactate synthase complex Updated DEFINITION A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.
2006-01-26 GO:0000062 fatty-acyl-CoA binding Updated DEFINITION Interacting selectively with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.
2006-01-26 GO:0046949 fatty-acyl-CoA biosynthetic process Updated DEFINITION The formation from simpler components of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
2006-01-26 GO:0006637 acyl-CoA metabolic process Updated DEFINITION The chemical reactions involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
2006-01-26 GO:0005541 acyl-CoA or acyl binding Updated DEFINITION OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid.
2006-01-26 GO:0008415 acyltransferase activity Updated DEFINITION Catalysis of the generalized reaction: acyl-carrier + reactant = acyl-reactant + carrier.
2006-01-26 GO:0008726 alkanesulfonate monooxygenase activity Updated DEFINITION Catalysis of the reaction: an alkanesulfonate + O2 + FMNH + H+ = an aldehyde + SO3(2-) (sulfite) + H2O + FMN+.
2006-01-26 GO:0009321 alkyl hydroperoxide reductase complex Updated DEFINITION An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.
2006-01-26 GO:0046353 aminoglycoside 3-N-acetyltransferase activity Updated DEFINITION Catalysis of the reaction: acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N3'-acetyl-2-deoxystreptamine antibiotic.
2006-01-26 GO:0018673 anthraniloyl-CoA monooxygenase activity Updated DEFINITION Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.
2006-01-26 GO:0019778 Atg12 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0019779 Atg8 activating enzyme Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0050473 arachidonate 15-lipoxygenase activity Updated DEFINITION Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
2006-01-26 GO:0004517 nitric-oxide synthase activity Updated DEFINITION Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
2006-01-26 GO:0046409 p-coumarate 3-hydroxylase activity Updated DEFINITION Catalysis of the 3-hydroxylation reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H20 + NADP+.
2006-01-26 GO:0046777 protein autophosphorylation Updated DEFINITION The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
2006-01-26 GO:0047134 protein-disulfide reductase activity Updated DEFINITION Catalysis of the reaction: protein-disulfide + NAD(P)H + H+ = protein-dithiol + NAD(P)+.
2006-01-26 GO:0008983 protein-glutamate O-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.
2006-01-26 GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester; this reaction is the methylation of peptidyl-L-leucine to form peptidyl-L-leucine methyl ester.
2006-01-26 GO:0016852 sirohydrochlorin cobaltochelatase activity Updated DEFINITION Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.
2006-01-26 GO:0008641 small protein activating enzyme activity Updated DEFINITION Catalysis of the activation of small proteins, such as ubiquitin, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0019948 SUMO activating enzyme activity Updated DEFINITION Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0031299 taurine-pyruvate aminotransferase activity Updated DEFINITION Catalysis of the reaction: taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde.
2006-01-26 GO:0004839 ubiquitin activating enzyme activity Updated DEFINITION Catalysis of the activation of the C-terminal carboxyl group of ubiquitin by the formation of a high-energy thiolester bond in an ATP-dependent manner.
2006-01-26 GO:0008642 ubiquitin-like activating enzyme activity Updated DEFINITION Catalysis of the activation of any small protein similar to ubiquitin, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0042292 URM1 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0047517 1,4-beta-D-xylan synthase activity Updated DEFINITION Catalysis of the reaction: UDP-D-xylose + 1,4-beta-D-xylan(n) = UDP + 1,4-beta-D-xylan(n+1).
2006-01-26 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex Updated DEFINITION An enzyme complex composed of two catalytic subunits, alpha1 and alpha2, which form a catalytic dimer, and a non-catalytic, regulatory subunit, beta. Modulates the action of platelet-activating factor (PAF).
2006-01-26 GO:0047011 2-dehydropantolactone reductase (A-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
2006-01-26 GO:0019141 2-dehydropantolactone reductase (B-specific) activity Updated DEFINITION Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
2006-01-26 GO:0047082 3,9-dihydroxypterocarpan 6a-monooxygenase activity Updated DEFINITION Catalysis of the reaction: O2 + NADPH + H+ + (6aR,11aR)-3,9-dihydroxypterocarpan = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.
2006-01-26 GO:0009316 3-isopropylmalate dehydratase complex Updated DEFINITION A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
2006-01-26 GO:0009334 3-phenylpropionate dioxygenase complex Updated DEFINITION Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol).
2006-01-26 GO:0047136 4-(dimethylamino)phenylazoxybenzene reductase activity Updated DEFINITION Catalysis of the reaction: 4-(dimethylamino)phenylazoxybenzene + NADPH + H+ = 4-dimethylaminophenylazobenzene + NADP+.
2006-01-26 GO:0047592 5-pyridoxate dioxygenase activity Updated DEFINITION Catalysis of the reaction: 3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + H+ + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+.
2006-01-26 GO:0047135 bis-gamma-glutamylcystine reductase activity Updated DEFINITION Catalysis of the reaction: bis-gamma-glutamylcystine + NADPH + H+ = 2 gamma-glutamylcysteine + NADP+.
2006-01-26 GO:0004183 carboxypeptidase E activity Updated DEFINITION Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents.
2006-01-26 GO:0018609 chlorobenzene dioxygenase activity Updated DEFINITION Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).
2006-01-26 GO:0004109 coproporphyrinogen oxidase activity Updated DEFINITION Catalysis of the reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O.
2006-01-26 GO:0051267 CP2 mannose-ethanolamine phosphotransferase activity Updated DEFINITION Catalysis of the reaction: ethanolamine phosphate (EtN-P) + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.
2006-01-26 GO:0045441 deacetoxycephalosporin C synthetase activity Updated DEFINITION Catalysis of the formation of deacetoxycephalosporin from penicillin-N.
2006-01-26 GO:0019780 FAT10 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0046424 ferulate 5-hydroxylase activity Updated DEFINITION Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+.
2006-01-26 GO:0008752 FMN reductase activity Updated DEFINITION Catalysis of the reaction: FMNH + H+ + NAD(P)+ = FMN+ + NAD(P)H + H+.
2006-01-26 GO:0008883 glutamyl-tRNA reductase activity Updated DEFINITION Catalysis of the reaction: L-glutamate 1-semialdehyde + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + NADPH + H+.
2006-01-26 GO:0042293 Hub1 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0050501 hyaluronan synthase activity Updated DEFINITION Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)](n) + 2n UDP.
2006-01-26 GO:0019782 ISG15 activating enzyme activity Updated DEFINITION Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.
2006-01-26 GO:0045439 isopenicillin-N epimerase activity Updated DEFINITION Catalysis of the reaction: isopenicillin-N = penicillin-N.
2006-01-26 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity Updated DEFINITION Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.
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