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GO Term History: Displaying 48 audit records for all terms for the date 2006-01-24

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2006-01-24 GO:0004692 cGMP-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cGMP.
2006-01-24 GO:0042624 ATPase activity, uncoupled Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; not directly coupled to any other reaction.
2006-01-24 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity Updated DEFINITION Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.
2006-01-24 GO:0016464 chloroplast protein-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.
2006-01-24 GO:0016289 CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.
2006-01-24 GO:0004690 cyclic nucleotide-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a cyclic nucleotide.
2006-01-24 GO:0004693 cyclin-dependent protein serine/threonine kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2006-01-24 GO:0051744 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity Updated DEFINITION Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.
2006-01-24 GO:0004676 3-phosphoinositide-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a 3-phosphoinositide.
2006-01-24 GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.
2006-01-24 GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.
2006-01-24 GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.
2006-01-24 GO:0003994 aconitate hydratase activity Updated DEFINITION Catalysis of the reaction: citrate = cis-aconitate + H2O = isocitrate; i.e. the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
2006-01-24 GO:0008827 cytochrome o ubiquinol oxidase activity Updated DEFINITION Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2R; cytochrome O is the electron acceptor.
2006-01-24 GO:0008094 DNA-dependent ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of double-stranded DNA; drives another reaction.
2006-01-24 GO:0003887 DNA-directed DNA polymerase activity Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2006-01-24 GO:0003899 DNA-directed RNA polymerase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2006-01-24 GO:0016631 enoyl-[acyl-carrier-protein] reductase activity Updated DEFINITION Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.
2006-01-24 GO:0043275 glutamate carboxypeptidase II activity Updated DEFINITION Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu.
2006-01-24 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism Updated DEFINITION Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out); by a phosphorylative mechanism.
2006-01-24 GO:0018466 limonene-1,2-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.
2006-01-24 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; activity is dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2006-01-24 GO:0008566 mitochondrial protein-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.
2006-01-24 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R = purine, and H = C, A, or U.
2006-01-24 GO:0050120 N-acetylhexosamine 1-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: H2O + NAD+ + N-acetyl-D-glucosamine = NADH + N-acetyl-D-glucosaminate.
2006-01-24 GO:0050122 N-acylhexosamine oxidase activity Updated DEFINITION Catalysis of the reaction: H2O + O2 + N-acetyl-D-glucosamine = H2O2 + N-acetyl-D-glucosaminate.
2006-01-24 GO:0050426 peptidyl-glycinamidase activity Updated DEFINITION Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide.
2006-01-24 GO:0009781 photosynthetic water oxidation Updated DEFINITION Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
2006-01-24 GO:0008564 protein-exporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the concomitant secretion of proteins.
2006-01-24 GO:0051743 red chlorophyll catabolite reductase activity Updated DEFINITION Catalysis of the reaction: red chlorophyll catabolite (RCC) + reduced ferredoxin + 2 H+ = primary fluorescent catabolite (pFCC) + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite to a colorless tetrapyrrole with a strong blue fluorescence.
2006-01-24 GO:0008186 RNA-dependent ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of RNA; drives another reaction.
2006-01-24 GO:0003968 RNA-directed RNA polymerase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2006-01-24 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.
2006-01-24 GO:0043142 single-stranded DNA-dependent ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single-stranded DNA; drives another reaction.
2006-01-24 GO:0008554 sodium-exporting ATPase activity, phosphorylative mechanism Updated DEFINITION Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism.
2006-01-24 GO:0047299 tryptophan-phenylpyruvate transaminase activity Updated DEFINITION Catalysis of the reaction: phenylpyruvate + L-tryptophan = L-phenylalanine + indolepyruvate.
2006-01-24 GO:0043365 [formate-C-acetyltransferase]-activating enzyme activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical.
2006-01-24 GO:0043214 bacteriocin-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the transport of bacteriocins across a membrane.
2006-01-24 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity Updated DEFINITION Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.
2006-01-24 GO:0004691 cAMP-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2006-01-24 GO:0050425 carboxypeptidase B activity Updated DEFINITION Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid.
2006-01-24 GO:0050424 alanine carboxypeptidase activity Updated DEFINITION Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups.
2006-01-24 GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity Updated DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2006-01-24 GO:0004679 AMP-activated protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of AMP.
2006-01-24 GO:0047138 aquacobalamin reductase activity Updated DEFINITION Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+.
2006-01-24 GO:0043140 ATP-dependent 3'-5' DNA helicase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'.
2006-01-24 GO:0043141 ATP-dependent 5'-3' DNA helicase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'.
2006-01-24 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity Updated DEFINITION Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2006-01-24 GO:0004692 cGMP-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cGMP.
2006-01-24 GO:0042624 ATPase activity, uncoupled Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; not directly coupled to any other reaction.
2006-01-24 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity Updated DEFINITION Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.
2006-01-24 GO:0016464 chloroplast protein-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.
2006-01-24 GO:0016289 CoA hydrolase activity Updated DEFINITION Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.
2006-01-24 GO:0004690 cyclic nucleotide-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a cyclic nucleotide.
2006-01-24 GO:0004693 cyclin-dependent protein serine/threonine kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2006-01-24 GO:0051744 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity Updated DEFINITION Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.
2006-01-24 GO:0004676 3-phosphoinositide-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a 3-phosphoinositide.
2006-01-24 GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.
2006-01-24 GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.
2006-01-24 GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.
2006-01-24 GO:0003994 aconitate hydratase activity Updated DEFINITION Catalysis of the reaction: citrate = cis-aconitate + H2O = isocitrate; i.e. the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
2006-01-24 GO:0008827 cytochrome o ubiquinol oxidase activity Updated DEFINITION Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2R; cytochrome O is the electron acceptor.
2006-01-24 GO:0008094 DNA-dependent ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of double-stranded DNA; drives another reaction.
2006-01-24 GO:0003887 DNA-directed DNA polymerase activity Updated DEFINITION Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2006-01-24 GO:0003899 DNA-directed RNA polymerase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2006-01-24 GO:0016631 enoyl-[acyl-carrier-protein] reductase activity Updated DEFINITION Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.
2006-01-24 GO:0043275 glutamate carboxypeptidase II activity Updated DEFINITION Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu.
2006-01-24 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism Updated DEFINITION Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out); by a phosphorylative mechanism.
2006-01-24 GO:0018466 limonene-1,2-diol dehydrogenase activity Updated DEFINITION Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.
2006-01-24 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; activity is dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2006-01-24 GO:0008566 mitochondrial protein-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.
2006-01-24 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R = purine, and H = C, A, or U.
2006-01-24 GO:0050120 N-acetylhexosamine 1-dehydrogenase activity Updated DEFINITION Catalysis of the reaction: H2O + NAD+ + N-acetyl-D-glucosamine = NADH + N-acetyl-D-glucosaminate.
2006-01-24 GO:0050122 N-acylhexosamine oxidase activity Updated DEFINITION Catalysis of the reaction: H2O + O2 + N-acetyl-D-glucosamine = H2O2 + N-acetyl-D-glucosaminate.
2006-01-24 GO:0050426 peptidyl-glycinamidase activity Updated DEFINITION Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide.
2006-01-24 GO:0009781 photosynthetic water oxidation Updated DEFINITION Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
2006-01-24 GO:0008564 protein-exporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the concomitant secretion of proteins.
2006-01-24 GO:0051743 red chlorophyll catabolite reductase activity Updated DEFINITION Catalysis of the reaction: red chlorophyll catabolite (RCC) + reduced ferredoxin + 2 H+ = primary fluorescent catabolite (pFCC) + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite to a colorless tetrapyrrole with a strong blue fluorescence.
2006-01-24 GO:0008186 RNA-dependent ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of RNA; drives another reaction.
2006-01-24 GO:0003968 RNA-directed RNA polymerase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template.
2006-01-24 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.
2006-01-24 GO:0043142 single-stranded DNA-dependent ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single-stranded DNA; drives another reaction.
2006-01-24 GO:0008554 sodium-exporting ATPase activity, phosphorylative mechanism Updated DEFINITION Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism.
2006-01-24 GO:0047299 tryptophan-phenylpyruvate transaminase activity Updated DEFINITION Catalysis of the reaction: phenylpyruvate + L-tryptophan = L-phenylalanine + indolepyruvate.
2006-01-24 GO:0043365 [formate-C-acetyltransferase]-activating enzyme activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical.
2006-01-24 GO:0043214 bacteriocin-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the transport of bacteriocins across a membrane.
2006-01-24 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity Updated DEFINITION Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.
2006-01-24 GO:0004691 cAMP-dependent protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP.
2006-01-24 GO:0050425 carboxypeptidase B activity Updated DEFINITION Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid.
2006-01-24 GO:0050424 alanine carboxypeptidase activity Updated DEFINITION Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups.
2006-01-24 GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity Updated DEFINITION Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol.
2006-01-24 GO:0004679 AMP-activated protein kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of AMP.
2006-01-24 GO:0047138 aquacobalamin reductase activity Updated DEFINITION Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+.
2006-01-24 GO:0043140 ATP-dependent 3'-5' DNA helicase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'.
2006-01-24 GO:0043141 ATP-dependent 5'-3' DNA helicase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'.
2006-01-24 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity Updated DEFINITION Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.
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