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GO Term History: Displaying 500 audit records for all terms for the date 2005-10-21

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM minus-end F-actin capping activity
2005-10-21 GO:0045639 positive regulation of myeloid cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of myeloid cell differentiation.
2005-10-21 GO:0045663 positive regulation of myoblast differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of myoblast differentiation.
2005-10-21 GO:0045846 positive regulation of natural killer cell activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer cell activity.
2005-10-21 GO:0043323 positive regulation of natural killer cell degranulation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer cell degranulation.
2005-10-21 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer cell mediated cytotoxicity.
2005-10-21 GO:0050924 positive regulation of negative chemotaxis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM minus-end actin filament capping activity
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM pointed-end F-actin capping activity
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM pointed-end actin capping activity
2005-10-21 GO:0051695 actin filament uncapping Added SYNONYM F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus end F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus end actin filament uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus-end F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus-end actin filament uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM pointed end F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM pointed end actin filament uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM pointed-end F-actin uncapping
2005-10-21 GO:0051016 barbed-end actin filament capping Deleted SYNONYM F-actin capping activity
2005-10-21 GO:0048629 trichome patterning Added SYNONYM trichome pattern formation
2005-10-21 GO:0048629 trichome patterning Added SYNONYM trichome spacing
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM barbed end F-actin uncapping
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM barbed end actin filament uncapping
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM plus end F-actin uncapping
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM plus end actin filament uncapping
2005-10-21 GO:0051693 actin filament capping Added SYNONYM F-actin capping activity
2005-10-21 GO:0051693 actin filament capping Added SYNONYM actin capping activity
2005-10-21 GO:0048326 positive regulation of axial mesodermal cell fate determination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axial mesoderm cell fate determination.
2005-10-21 GO:0048330 positive regulation of axial mesodermal cell fate specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axial mesoderm cell fate specification.
2005-10-21 GO:0045773 positive regulation of axon extension Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axon extension.
2005-10-21 GO:0050772 positive regulation of axonogenesis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axonogenesis.
2005-10-21 GO:0050871 positive regulation of B cell activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of B cell activation.
2005-10-21 GO:0045579 positive regulation of B cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of B cell differentiation.
2005-10-21 GO:0045836 positive regulation of meiotic nuclear division Updated DEFINITION Any process that activates or increases the rate, frequency or extent of meiosis.
2005-10-21 GO:0045636 positive regulation of melanocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of melanocyte differentiation.
2005-10-21 GO:0045838 positive regulation of membrane potential Updated DEFINITION Any process that activates or increases the rate, frequency or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2005-10-21 GO:0051044 positive regulation of membrane protein ectodomain proteolysis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of membrane protein ectodomain peptidolysis.
2005-10-21 GO:0043382 positive regulation of memory T cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of memory T cell differentiation.
2005-10-21 GO:0048336 positive regulation of mesodermal cell fate determination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mesoderm cell fate determination.
2005-10-21 GO:0048337 positive regulation of mesodermal cell fate specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mesoderm cell fate specification.
2005-10-21 GO:0009910 negative regulation of flower development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of flower development.
2005-10-21 GO:0046882 negative regulation of follicle-stimulating hormone secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of follicle-stimulating hormone.
2005-10-21 GO:0050753 negative regulation of fractalkine biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.
2005-10-21 GO:0045810 negative regulation of frizzled signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the frizzled signaling pathway.
2005-10-21 GO:0045812 negative regulation of Wnt signaling pathway, calcium modulating pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the frizzled-2 signaling pathway.
2005-10-21 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of G-protein coupled receptor protein signaling pathway activity.
2005-10-21 GO:0046644 negative regulation of gamma-delta T cell activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gamma-delta T cell activation.
2005-10-21 GO:0045587 negative regulation of gamma-delta T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gamma-delta T cell differentiation.
2005-10-21 GO:0046647 negative regulation of gamma-delta T cell proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gamma-delta T cell proliferation.
2005-10-21 GO:0009938 negative regulation of gibberellic acid mediated signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gibberellic acid mediated signaling activity.
2005-10-21 GO:0045686 negative regulation of glial cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of glia cell differentiation.
2005-10-21 GO:0045816 negative regulation of transcription from RNA polymerase II promoter, global Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of global transcription from an RNA polymerase II promoter.
2005-10-21 GO:0045721 negative regulation of gluconeogenesis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gluconeogenesis.
2005-10-21 GO:0046325 negative regulation of glucose import Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
2005-10-21 GO:0046318 negative regulation of glucosylceramide biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of glucosylceramide.
2005-10-21 GO:0045719 negative regulation of glycogen biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of glycogen.
2005-10-21 GO:0045818 negative regulation of glycogen catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown into simpler components of glycogen.
2005-10-21 GO:0045820 negative regulation of glycolytic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of glycolysis.
2005-10-21 GO:0043002 negative regulation of Golgi to plasma membrane CFTR protein transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.
2005-10-21 GO:0042997 negative regulation of Golgi to plasma membrane protein transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the transport of proteins from the Golgi to the plasma membrane.
2005-10-21 GO:0048216 negative regulation of Golgi vesicle fusion to target membrane Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Golgi vesicle fusion to target membrane.
2005-10-21 GO:0030853 negative regulation of granulocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of granulocyte differentiation.
2005-10-21 GO:0045424 negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of granulocyte macrophage colony-stimulating factor.
2005-10-21 GO:0031283 negative regulation of guanylate cyclase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of guanylate cyclase activity.
2005-10-21 GO:0042636 negative regulation of hair cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
2005-10-21 GO:0045822 negative regulation of heart contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of heart contraction.
2005-10-21 GO:0045611 negative regulation of hemocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of hemocyte differentiation.
2005-10-21 GO:0046986 negative regulation of hemoglobin biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
2005-10-21 GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of hepatocyte growth factor.
2005-10-21 GO:0051617 negative regulation of histamine uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of histamine into a cell.
2005-10-21 GO:0050669 negative regulation of homocysteine metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving homocysteine.
2005-10-21 GO:0045348 positive regulation of MHC class II biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of MHC class II.
2005-10-21 GO:0031117 positive regulation of microtubule depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of microtubule depolymerization.
2005-10-21 GO:0031116 positive regulation of microtubule polymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of microtubule polymerization.
2005-10-21 GO:0031112 positive regulation of microtubule polymerization or depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of microtubule polymerization or depolymerization.
2005-10-21 GO:0045840 positive regulation of mitotic nuclear division Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mitosis.
2005-10-21 GO:0045931 positive regulation of mitotic cell cycle Updated DEFINITION Any process that activates or increases the rate, frequency or extent of progression through the mitotic cell cycle.
2005-10-21 GO:0045977 positive regulation of mitotic cell cycle, embryonic Updated DEFINITION Any process that activates or increases the rate, frequency or extent of progression through the embryonic mitotic cell cycle.
2005-10-21 GO:0046604 positive regulation of mitotic centrosome separation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of centrosome separation.
2005-10-21 GO:0045842 positive regulation of mitotic metaphase/anaphase transition Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the mitotic metaphase to anaphase transition.
2005-10-21 GO:0045951 positive regulation of mitotic recombination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of DNA recombination during mitosis.
2005-10-21 GO:0045657 positive regulation of monocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of monocyte differentiation.
2005-10-21 GO:0051515 positive regulation of monopolar cell growth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of monopolar cell growth, polarized growth from one end of a cell.
2005-10-21 GO:0031442 positive regulation of mRNA 3'-end processing Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mRNA 3'-end processing.
2005-10-21 GO:0031439 positive regulation of mRNA cleavage Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mRNA cleavage.
2005-10-21 GO:0050685 positive regulation of mRNA processing Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mRNA processing.
2005-10-21 GO:0051149 positive regulation of muscle cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of muscle cell differentiation.
2005-10-21 GO:0045933 positive regulation of muscle contraction Updated DEFINITION Any process that activates or increases the rate, frequency or extent of muscle contraction.
2005-10-21 GO:0031643 positive regulation of myelination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation of a myelin sheath around nerve axons.
2005-10-21 GO:0010187 negative regulation of seed germination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of seed germination.
2005-10-21 GO:0051283 negative regulation of sequestering of calcium ion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
2005-10-21 GO:0051612 negative regulation of serotonin uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of serotonin into a cell.
2005-10-21 GO:0045873 negative regulation of sevenless signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the sevenless signaling pathway.
2005-10-21 GO:0009968 negative regulation of signal transduction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signal transduction.
2005-10-21 GO:0009893 positive regulation of metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of chemical reactions involving a substance.
2005-10-21 GO:0045345 positive regulation of MHC class I biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of MHC class I.
2005-10-21 GO:0045565 negative regulation of TRAIL receptor 1 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.
2005-10-21 GO:0045623 negative regulation of T-helper cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T-helper cell differentiation.
2005-10-21 GO:0048239 negative regulation of DNA recombination at telomere Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of genetic recombination within the telomere.
2005-10-21 GO:0050760 negative regulation of thymidylate synthase biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of the enzyme thymidylate synthase.
2005-10-21 GO:0045751 negative regulation of Toll signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the Tl signaling pathway.
2005-10-21 GO:0045555 negative regulation of TRAIL biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of TRAIL, TNF-related apoptosis inducing ligand.
2005-10-21 GO:0051396 positive regulation of nerve growth factor receptor activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the activity of the nerve growth factor receptor.
2005-10-21 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the activity of the nerve growth factor receptor signaling pathway.
2005-10-21 GO:0050769 positive regulation of neurogenesis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neurogenesis, the origin and formation of neurons.
2005-10-21 GO:0045666 positive regulation of neuron differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neuron differentiation.
2005-10-21 GO:0031646 positive regulation of neurological system process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of a neurophysiological process.
2005-10-21 GO:0001956 positive regulation of neurotransmitter secretion Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the regulated release of a neurotransmitter.
2005-10-21 GO:0051590 positive regulation of neurotransmitter transport Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of a neurotransmitter into, out of, within or between cells.
2005-10-21 GO:0051582 positive regulation of neurotransmitter uptake Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of a neurotransmitter into a cell.
2005-10-21 GO:0043315 positive regulation of neutrophil degranulation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neutrophil degranulation.
2005-10-21 GO:0045660 positive regulation of neutrophil differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neutrophil differentiation.
2005-10-21 GO:0042346 positive regulation of NF-kappaB import into nucleus Updated DEFINITION Any process that activates or increases the rate, frequency or extent of transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
2005-10-21 GO:0051533 positive regulation of NFAT protein import into nucleus Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-10-21 GO:0045429 positive regulation of nitric oxide biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of nitric oxide.
2005-10-21 GO:0045908 negative regulation of vasodilation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of vasodilation.
2005-10-21 GO:0045071 negative regulation of viral genome replication Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of viral genome replication.
2005-10-21 GO:0048525 negative regulation of viral process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.
2005-10-21 GO:0046597 negative regulation of viral entry into host cell Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of virus particles into the cell.
2005-10-21 GO:0046137 negative regulation of vitamin metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
2005-10-21 GO:0040027 negative regulation of vulval development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of development of the vulva, as in, but not restricted to, the roundworms (Nematoda, ncbi_taxonomy_id:6231).
2005-10-21 GO:0030178 negative regulation of Wnt signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Wnt receptor signaling pathway activity.
2005-10-21 GO:0050944 negative regulation of xanthophore differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of xanthophore differentiation.
2005-10-21 GO:0051694 pointed-end actin filament capping Added DEFINITION The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added DEFINITION The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
2005-10-21 GO:0010116 positive regulation of abscisic acid biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of abscisic acid biosynthesis.
2005-10-21 GO:0009789 positive regulation of abscisic acid-activated signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of abscisic acid mediated signal transduction.
2005-10-21 GO:0045754 positive regulation of acetate catabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the breakdown into simpler components of acetate.
2005-10-21 GO:0051633 positive regulation of acetylcholine uptake Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of acetylcholine into a cell.
2005-10-21 GO:0030836 positive regulation of actin filament depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of actin depolymerization.
2005-10-21 GO:0030838 positive regulation of actin filament polymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of actin polymerization.
2005-10-21 GO:0051127 positive regulation of actin nucleation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
2005-10-21 GO:0045758 obsolete positive regulation of actin polymerization and/or depolymerization Updated DEFINITION OBSOLETE. Any process that activates or increases the rate, frequency or extent of actin polymerization and/or depolymerization.
2005-10-21 GO:0045760 positive regulation of action potential Updated DEFINITION Any process that activates or increases the rate, frequency or extent of action potential creation, propagation or termination.
2005-10-21 GO:0045762 positive regulation of adenylate cyclase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of adenylate cyclase activity.
2005-10-21 GO:0051461 positive regulation of corticotropin secretion Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the regulated release of adrenocorticotropin hormone from a cell or group of cells.
2005-10-21 GO:0048084 positive regulation of adult chitin-containing cuticle pigmentation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
2005-10-21 GO:0045711 positive regulation of adult salivary gland boundary specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of salivary gland determination in an adult organism.
2005-10-21 GO:0046635 positive regulation of alpha-beta T cell activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of alpha-beta T cell activation.
2005-10-21 GO:0046638 positive regulation of alpha-beta T cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of alpha-beta T cell differentiation.
2005-10-21 GO:0046641 positive regulation of alpha-beta T cell proliferation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of alpha-beta T cell proliferation.
2005-10-21 GO:0045764 positive regulation of cellular amino acid metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving amino acid.
2005-10-21 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the biosynthesis of amyloid precursor protein (APP), the precursor of beta-amyloid.
2005-10-21 GO:0031542 positive regulation of anthocyanin biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation of anthocyanins from simpler components.
2005-10-21 GO:0031539 positive regulation of anthocyanin metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of chemical reactions involving anthocyanins.
2005-10-21 GO:0045768 obsolete positive regulation of anti-apoptosis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of anti-apoptosis.
2005-10-21 GO:0001815 positive regulation of antibody-dependent cellular cytotoxicity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of antibody-dependent cellular cytotoxicity.
2005-10-21 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
2005-10-21 GO:0045690 positive regulation of antipodal cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of antipodal cell differentiation.
2005-10-21 GO:0043065 positive regulation of apoptotic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of cell death by apoptosis.
2005-10-21 GO:0048711 positive regulation of astrocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of astrocyte differentiation.
2005-10-21 GO:0045770 positive regulation of asymmetric cell division Updated DEFINITION Any process that activates or increases the rate, frequency or extent of asymmetric cell division.
2005-10-21 GO:0045609 positive regulation of auditory receptor cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of auditory hair cell differentiation.
2005-10-21 GO:0045698 negative regulation of synergid differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synergid cell differentiation.
2005-10-21 GO:0010113 negative regulation of systemic acquired resistance Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of systemic acquired resistance.
2005-10-21 GO:0050868 negative regulation of T cell activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T cell activation.
2005-10-21 GO:0045581 negative regulation of T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T cell differentiation.
2005-10-21 GO:0050860 negative regulation of T cell receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
2005-10-21 GO:0045626 negative regulation of T-helper 1 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T-helper 1 cell differentiation.
2005-10-21 GO:0045629 negative regulation of T-helper 2 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T-helper 2 cell differentiation.
2005-10-21 GO:0045935 positive regulation of nucleobase-containing compound metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nucleobases, nucleosides, nucleotides and nucleic acids.
2005-10-21 GO:0046824 positive regulation of nucleocytoplasmic transport Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of substances between the nucleus and the cytoplasm.
2005-10-21 GO:0045979 positive regulation of nucleoside metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nucleosides.
2005-10-21 GO:0030810 positive regulation of nucleotide biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nucleotide biosynthesis.
2005-10-21 GO:0030813 positive regulation of nucleotide catabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nucleotide catabolism.
2005-10-21 GO:0045981 positive regulation of nucleotide metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nucleotides.
2005-10-21 GO:0045850 positive regulation of nurse cell apoptotic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nurse cell apoptosis.
2005-10-21 GO:0042482 positive regulation of odontogenesis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation and development of a tooth or teeth.
2005-10-21 GO:0042485 positive regulation of odontogenesis of calcareous or chitinous tooth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation and development of a tooth, any hard calcareous or chitinous organ found in the mouth and used in feeding or procuring food, e.g. a mollusk or starfish tooth. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).
2005-10-21 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. As in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2005-10-21 GO:0048714 positive regulation of oligodendrocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of oligodendrocyte differentiation.
2005-10-21 GO:0046622 positive regulation of organ growth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of growth of an organ of an organism.
2005-10-21 GO:0044253 positive regulation of multicellular organismal metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2005-10-21 GO:0051240 positive regulation of multicellular organismal process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of an organismal physiological process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
2005-10-21 GO:0046012 positive regulation of oskar mRNA translation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of oskar mRNA translation.
2005-10-21 GO:0045778 positive regulation of ossification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of bone formation.
2005-10-21 GO:0045669 positive regulation of osteoblast differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of osteoblast differentiation.
2005-10-21 GO:0045672 positive regulation of osteoclast differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of osteoclast differentiation.
2005-10-21 GO:0051353 positive regulation of oxidoreductase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
2005-10-21 GO:0048346 positive regulation of paraxial mesodermal cell fate determination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of paraxial mesoderm cell fate determination.
2005-10-21 GO:0048350 positive regulation of paraxial mesodermal cell fate specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of paraxial mesoderm cell fate specification.
2005-10-21 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the phosphorylation of peptidyl-tyrosine.
2005-10-21 GO:0050766 positive regulation of phagocytosis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of phagocytosis.
2005-10-21 GO:0045937 positive regulation of phosphate metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving phosphates.
2005-10-21 GO:0045949 positive regulation of phosphorus utilization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of phosphorus utilization.
2005-10-21 GO:0042327 positive regulation of phosphorylation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of addition of phosphoric groups to a molecule.
2005-10-21 GO:0046534 positive regulation of photoreceptor cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of photoreceptor differentiation.
2005-10-21 GO:0045675 positive regulation of photoreceptor differentiation (sensu Endopterygota) Updated DEFINITION Any process that activates or increases the rate, frequency or extent of photoreceptor differentiation. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2005-10-21 GO:0043119 positive regulation of physiological process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2005-10-21 GO:0050942 positive regulation of pigment cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of pigment cell differentiation.
2005-10-21 GO:0045615 positive regulation of plasmatocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of plasmatocyte differentiation.
2005-10-21 GO:0050709 negative regulation of protein secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a protein from a cell or group of cells.
2005-10-21 GO:0051224 negative regulation of protein transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a protein into, out of, within or between cells.
2005-10-21 GO:0031397 negative regulation of protein ubiquitination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the addition of ubiquitin moieties to a protein.
2005-10-21 GO:0045861 negative regulation of proteolysis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the hydrolysis of a peptide bond or bonds within a protein.
2005-10-21 GO:0031273 negative regulation of pseudopodium assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the assembly of pseudopodia.
2005-10-21 GO:0045863 negative regulation of pteridine metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving pteridine.
2005-10-21 GO:0045982 negative regulation of purine nucleobase metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving purine bases.
2005-10-21 GO:0045984 negative regulation of pyrimidine nucleobase metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving pyrimidine bases.
2005-10-21 GO:0045677 negative regulation of R7 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of R7 differentiation.
2005-10-21 GO:0045680 negative regulation of R8 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of R8 differentiation.
2005-10-21 GO:0046580 negative regulation of Ras protein signal transduction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Ras protein signal transduction.
2005-10-21 GO:0048261 negative regulation of receptor-mediated endocytosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
2005-10-21 GO:0000020 obsolete negative regulation of recombination within rDNA repeats Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.
2005-10-21 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
2005-10-21 GO:0048585 negative regulation of response to stimulus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
2005-10-21 GO:0046673 negative regulation of compound eye retinal cell programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of programmed cell death that occurs in the retina. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2005-10-21 GO:0046671 negative regulation of retinal cell programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of programmed cell death that occurs in the retina.
2005-10-21 GO:0048387 negative regulation of retinoic acid receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of retinoic acid receptor signaling pathway activity.
2005-10-21 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of retroviral genome replication.
2005-10-21 GO:0045871 negative regulation of rhodopsin gene expression Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of rhodopsin gene activity.
2005-10-21 GO:0046832 negative regulation of RNA export from nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of RNA from the nucleus into the cytoplasm.
2005-10-21 GO:0046829 negative regulation of RNA import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the movement of RNA from the cytoplasm into the nucleus.
2005-10-21 GO:0051253 negative regulation of RNA metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving RNA.
2005-10-21 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of S phase of mitotic cell cycle activity.
2005-10-21 GO:0045705 negative regulation of salivary gland boundary specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of salivary gland determination.
2005-10-21 GO:0051048 negative regulation of secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a substance from a cell or group of cells.
2005-10-21 GO:0042177 negative regulation of protein catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2005-10-21 GO:0043242 negative regulation of protein complex disassembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
2005-10-21 GO:0046826 negative regulation of protein export from nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of proteins from the nucleus into the cytoplasm.
2005-10-21 GO:0042308 negative regulation of protein import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the movement of proteins from the cytoplasm into the nucleus.
2005-10-21 GO:0006469 negative regulation of protein kinase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of protein kinase activity.
2005-10-21 GO:0051248 negative regulation of protein metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of chemical reactions involving a protein.
2005-10-21 GO:0031400 negative regulation of protein modification process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the covalent alteration of one or more amino acid residues within a protein.
2005-10-21 GO:0045567 negative regulation of TRAIL receptor 2 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.
2005-10-21 GO:0045563 negative regulation of TRAIL receptor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of the TRAIL (TNF-related apoptosis inducing ligand) receptor.
2005-10-21 GO:0016481 negative regulation of transcription Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription.
2005-10-21 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
2005-10-21 GO:0042992 negative regulation of transcription factor import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the movement of a transcription factor from the cytoplasm to the nucleus.
2005-10-21 GO:0016479 negative regulation of transcription from RNA polymerase I promoter Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase I promoter.
2005-10-21 GO:0007069 negative regulation of transcription from RNA polymerase I promoter during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase I promoter during mitosis.
2005-10-21 GO:0000122 negative regulation of transcription from RNA polymerase II promoter Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase II promoter.
2005-10-21 GO:0007070 negative regulation of transcription from RNA polymerase II promoter during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase II promoter during mitosis.
2005-10-21 GO:0016480 negative regulation of transcription from RNA polymerase III promoter Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase III promoter.
2005-10-21 GO:0007071 negative regulation of transcription from RNA polymerase III promoter during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase III promoter during mitosis.
2005-10-21 GO:0006340 obsolete negative regulation of transcription of homeotic gene (Polycomb group) Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of transcription of homeotic genes of the Polycomb group.
2005-10-21 GO:0045891 obsolete negative regulation of transcription of homeotic gene (trithorax group) Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of transcription of homeotic genes of the trithorax group.
2005-10-21 GO:0045892 negative regulation of transcription, DNA-templated Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of DNA-dependent transcription.
2005-10-21 GO:0051038 negative regulation of transcription involved in meiotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription during meiosis.
2005-10-21 GO:0007068 negative regulation of transcription during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription during mitosis.
2005-10-21 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcriptional preinitiation complex formation.
2005-10-21 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of any TGFbeta receptor signaling pathway.
2005-10-21 GO:0045900 negative regulation of translational elongation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of translational elongation.
2005-10-21 GO:0045902 negative regulation of translational fidelity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of activities to ensure translational fidelity.
2005-10-21 GO:0045947 negative regulation of translational initiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of translational initiation.
2005-10-21 GO:0045904 negative regulation of translational termination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of translational termination.
2005-10-21 GO:0051051 negative regulation of transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
2005-10-21 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of biosynthesis of tumor necrosis factor-alpha, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
2005-10-21 GO:0043018 negative regulation of lymphotoxin A biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of the cytokine tumor necrosis factor-beta.
2005-10-21 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
2005-10-21 GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat1 protein.
2005-10-21 GO:0042514 negative regulation of tyrosine phosphorylation of Stat2 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat2 protein.
2005-10-21 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat3 protein.
2005-10-21 GO:0042521 negative regulation of tyrosine phosphorylation of Stat4 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat4 protein.
2005-10-21 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat5 protein.
2005-10-21 GO:0045875 negative regulation of sister chromatid cohesion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sister chromatid cohesion.
2005-10-21 GO:0048642 negative regulation of skeletal muscle tissue development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle development.
2005-10-21 GO:0048744 negative regulation of skeletal muscle fiber development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle fiber development.
2005-10-21 GO:0048632 negative regulation of skeletal muscle tissue growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle growth.
2005-10-21 GO:0043417 negative regulation of skeletal muscle tissue regeneration Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle regeneration.
2005-10-21 GO:0051151 negative regulation of smooth muscle cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of smooth muscle cell differentiation.
2005-10-21 GO:0045986 negative regulation of smooth muscle contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of smooth muscle contraction.
2005-10-21 GO:0045879 negative regulation of smoothened signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of smoothened signaling.
2005-10-21 GO:0045701 negative regulation of spermatid nuclear differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of spermatid nuclear differentiation.
2005-10-21 GO:0042174 negative regulation of sporulation resulting in formation of a cellular spore Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sporulation.
2005-10-21 GO:0048688 negative regulation of sprouting of injured axon Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sprouting of an injured axon.
2005-10-21 GO:0031286 negative regulation of sorocarp stalk cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of stalk cell differentiation.
2005-10-21 GO:0045939 negative regulation of steroid metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving steroids.
2005-10-21 GO:0051497 negative regulation of stress fiber assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
2005-10-21 GO:0031447 negative regulation of fast-twitch skeletal muscle fiber contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated fast muscle contraction.
2005-10-21 GO:0031453 positive regulation of heterochromatin assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated mixed muscle contraction.
2005-10-21 GO:0051154 negative regulation of striated muscle cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated muscle cell differentiation.
2005-10-21 GO:0045988 negative regulation of striated muscle contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated muscle contraction.
2005-10-21 GO:0045843 negative regulation of striated muscle tissue development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated muscle development.
2005-10-21 GO:0031450 negative regulation of slow-twitch skeletal muscle fiber contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated slow muscle contraction.
2005-10-21 GO:0051175 negative regulation of sulfur metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving sulfur or compounds containing sulfur.
2005-10-21 GO:0045882 negative regulation of sulfur utilization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sulfur utilization.
2005-10-21 GO:0008634 obsolete negative regulation of survival gene product expression Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2005-10-21 GO:0045886 negative regulation of synaptic growth at neuromuscular junction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synaptic growth at neuromuscular junction.
2005-10-21 GO:0050805 negative regulation of synaptic transmission Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2005-10-21 GO:0031631 negative regulation of synaptic vesicle fusion to presynaptic membrane Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synaptic vesicle fusion to the presynaptic membrane.
2005-10-21 GO:0051511 negative regulation of unidimensional cell growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of unidimensional cell growth, the process by which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
2005-10-21 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of vascular endothelial growth factor receptor signaling pathway activity.
2005-10-21 GO:0045906 negative regulation of vasoconstriction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of vasoconstriction.
2005-10-21 GO:0051173 positive regulation of nitrogen compound metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nitrogen or nitrogenous compounds.
2005-10-21 GO:0045848 positive regulation of nitrogen utilization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nitrogen utilization.
2005-10-21 GO:0051135 positive regulation of NK T cell activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer T cell activation.
2005-10-21 GO:0051138 positive regulation of NK T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell differentiation.
2005-10-21 GO:0051142 positive regulation of NK T cell proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell proliferation.
2005-10-21 GO:0043071 positive regulation of non-apoptotic programmed cell death Updated DEFINITION Any process that activates or increases the rate, frequency or extent of non-apoptotic programmed cell death, cell death resulting from activation of endogenous cellular processes, by a mechanism other than apoptosis.
2005-10-21 GO:0051623 positive regulation of norepinephrine uptake Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of norepinephrine into a cell.
2005-10-21 GO:0045747 positive regulation of Notch signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the Notch signaling pathway.
2005-10-21 GO:0048347 negative regulation of paraxial mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of paraxial mesoderm cell fate determination.
2005-10-21 GO:0048351 negative regulation of paraxial mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of paraxial mesoderm cell fate specification.
2005-10-21 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the phosphorylation of peptidyl-tyrosine.
2005-10-21 GO:0050765 negative regulation of phagocytosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of phagocytosis.
2005-10-21 GO:0045936 negative regulation of phosphate metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving phosphates.
2005-10-21 GO:0045942 negative regulation of phosphorus utilization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of phosphorus utilization.
2005-10-21 GO:0046533 negative regulation of photoreceptor cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of photoreceptor differentiation.
2005-10-21 GO:0045674 negative regulation of photoreceptor differentiation (sensu Endopterygota) Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of photoreceptor differentiation. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2005-10-21 GO:0043155 negative regulation of photosynthesis, light reaction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the light-dependent reaction of photosynthesis.
2005-10-21 GO:0043118 negative regulation of physiological process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2005-10-21 GO:0050941 negative regulation of pigment cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of pigment cell differentiation.
2005-10-21 GO:0048550 negative regulation of pinocytosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of pinocytosis. Pinocytosis is the process whereby cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
2005-10-21 GO:0045614 negative regulation of plasmatocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of plasmatocyte differentiation.
2005-10-21 GO:0030861 negative regulation of polarized epithelial cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of polarized epithelial cell differentiation.
2005-10-21 GO:0045855 negative regulation of pole plasm oskar mRNA localization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the processes by which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
2005-10-21 GO:0050928 negative regulation of positive chemotaxis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
2005-10-21 GO:0048581 negative regulation of post-embryonic development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
2005-10-21 GO:0045837 negative regulation of membrane potential Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2005-10-21 GO:0051045 negative regulation of membrane protein ectodomain proteolysis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of membrane protein ectodomain proteolysis.
2005-10-21 GO:0048335 negative regulation of mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mesoderm cell fate determination.
2005-10-21 GO:0042662 negative regulation of mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mesoderm cell fate specification.
2005-10-21 GO:0009892 negative regulation of metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of chemical reactions involving a substance.
2005-10-21 GO:0048553 negative regulation of metalloenzyme activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.
2005-10-21 GO:0045344 negative regulation of MHC class I biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of MHC class I.
2005-10-21 GO:0045347 negative regulation of MHC class II biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of MHC class II.
2005-10-21 GO:0007026 negative regulation of microtubule depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-10-21 GO:0031115 negative regulation of microtubule polymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization.
2005-10-21 GO:0031111 negative regulation of microtubule polymerization or depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization or depolymerization.
2005-10-21 GO:0045839 negative regulation of mitotic nuclear division Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mitosis.
2005-10-21 GO:0046603 negative regulation of mitotic centrosome separation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of centrosome separation.
2005-10-21 GO:0045841 negative regulation of mitotic metaphase/anaphase transition Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the mitotic metaphase to anaphase transition.
2005-10-21 GO:0045656 negative regulation of monocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of monocyte differentiation.
2005-10-21 GO:0051514 negative regulation of monopolar cell growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of monopolar cell growth, polarized growth from one end of a cell.
2005-10-21 GO:0031441 negative regulation of mRNA 3'-end processing Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mRNA 3'-end processing.
2005-10-21 GO:0031438 negative regulation of mRNA cleavage Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mRNA cleavage.
2005-10-21 GO:0050686 negative regulation of mRNA processing Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mRNA processing.
2005-10-21 GO:0051148 negative regulation of muscle cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of muscle cell differentiation.
2005-10-21 GO:0045932 negative regulation of muscle contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of muscle contraction.
2005-10-21 GO:0048635 negative regulation of muscle organ development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of muscle development.
2005-10-21 GO:0031642 negative regulation of myelination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation of a myelin sheath around nerve axons.
2005-10-21 GO:0045638 negative regulation of myeloid cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of myeloid cell differentiation.
2005-10-21 GO:0045856 positive regulation of pole plasm oskar mRNA localization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the processes by which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
2005-10-21 GO:0043267 negative regulation of potassium ion transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of potassium ions (K+) into, out of, within or between cells.
2005-10-21 GO:0043069 negative regulation of programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
2005-10-21 GO:0045786 negative regulation of cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the cell cycle.
2005-10-21 GO:0045976 negative regulation of mitotic cell cycle, embryonic Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the embryonic mitotic cell cycle.
2005-10-21 GO:0051447 negative regulation of meiotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the meiotic cell cycle.
2005-10-21 GO:0045930 negative regulation of mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the mitotic cell cycle.
2005-10-21 GO:0046001 negative regulation of preblastoderm mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the preblastoderm mitotic cell cycle.
2005-10-21 GO:0046003 negative regulation of syncytial blastoderm mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the syncytial blastoderm mitotic cell cycle.
2005-10-21 GO:0031393 negative regulation of prostaglandin biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of prostaglandin biosynthesis.
2005-10-21 GO:0051201 negative regulation of prosthetic group metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions of a prosthetic group.
2005-10-21 GO:0017148 negative regulation of translation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of proteins.
2005-10-21 GO:0048380 negative regulation of lateral mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lateral mesoderm cell fate specification.
2005-10-21 GO:0031276 negative regulation of lateral pseudopodium assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the assembly of pseudopodia from the lateral side of the cell.
2005-10-21 GO:0045831 negative regulation of light-activated channel activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of light-activated channel activity.
2005-10-21 GO:0051055 negative regulation of lipid biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of lipids.
2005-10-21 GO:0050995 negative regulation of lipid catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown of lipids into simpler components.
2005-10-21 GO:0045833 negative regulation of lipid metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving lipids.
2005-10-21 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signaling in response to detection of lipopolysaccharide.
2005-10-21 GO:0050748 negative regulation of lipoprotein metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids.
2005-10-21 GO:0040013 negative regulation of locomotion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of locomotion of an organism.
2005-10-21 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of low-density lipoprotein receptors.
2005-10-21 GO:0051250 negative regulation of lymphocyte activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lymphocyte activation.
2005-10-21 GO:0045620 negative regulation of lymphocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lymphocyte differentiation.
2005-10-21 GO:0016242 negative regulation of macroautophagy Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of macroautophagy.
2005-10-21 GO:0043031 negative regulation of macrophage activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of macrophage activation.
2005-10-21 GO:0045650 negative regulation of macrophage differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of macrophage differentiation.
2005-10-21 GO:0048092 negative regulation of male pigmentation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of establishment of a pattern of pigment in males.
2005-10-21 GO:0043407 negative regulation of MAP kinase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of MAPK activity.
2005-10-21 GO:0043409 negative regulation of MAPK cascade Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signal transduction mediated by the MAPKKK cascade.
2005-10-21 GO:0031495 negative regulation of mating type switching Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mating type switching.
2005-10-21 GO:0045662 negative regulation of myoblast differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of myoblast differentiation.
2005-10-21 GO:0030102 negative regulation of natural killer cell activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer cell activity.
2005-10-21 GO:0050925 negative regulation of negative chemotaxis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
2005-10-21 GO:0051395 negative regulation of nerve growth factor receptor activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of the nerve growth factor receptor.
2005-10-21 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of the nerve growth factor receptor signaling pathway.
2005-10-21 GO:0007406 negative regulation of neuroblast proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the proliferation of neuroblasts.
2005-10-21 GO:0050768 negative regulation of neurogenesis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of neurogenesis, the origin and formation of neurons.
2005-10-21 GO:0045665 negative regulation of neuron differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of neuron differentiation.
2005-10-21 GO:0031645 negative regulation of neurological system process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of a neurophysiological process.
2005-10-21 GO:0046929 negative regulation of neurotransmitter secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a neurotransmitter.
2005-10-21 GO:0051589 negative regulation of neurotransmitter transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a neurotransmitter into, out of, within or between cells.
2005-10-21 GO:0051581 negative regulation of neurotransmitter uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a neurotransmitter into a cell.
2005-10-21 GO:0045659 negative regulation of neutrophil differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of neutrophil differentiation.
2005-10-21 GO:0042347 negative regulation of NF-kappaB import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
2005-10-21 GO:0045019 negative regulation of nitric oxide biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of nitric oxide.
2005-10-21 GO:0051172 negative regulation of nitrogen compound metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nitrogen or nitrogenous compounds.
2005-10-21 GO:0045847 negative regulation of nitrogen utilization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nitrogen utilization.
2005-10-21 GO:0051134 negative regulation of NK T cell activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell activation.
2005-10-21 GO:0051137 negative regulation of NK T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell differentiation.
2005-10-21 GO:0051141 negative regulation of NK T cell proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell proliferation.
2005-10-21 GO:0043072 negative regulation of non-apoptotic programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of non-apoptotic programmed cell death, cell death resulting from activation of endogenous cellular processes, by a mechanism other than apoptosis.
2005-10-21 GO:0051622 negative regulation of norepinephrine uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of norepinephrine into a cell.
2005-10-21 GO:0045746 negative regulation of Notch signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the Notch signaling pathway.
2005-10-21 GO:0045934 negative regulation of nucleobase-containing compound metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nucleobases, nucleosides, nucleotides and nucleic acids.
2005-10-21 GO:0046823 negative regulation of nucleocytoplasmic transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of substances between the cytoplasm and the nucleus.
2005-10-21 GO:0045978 negative regulation of nucleoside metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nucleosides.
2005-10-21 GO:0030809 negative regulation of nucleotide biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nucleotide biosynthesis.
2005-10-21 GO:0030812 negative regulation of nucleotide catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nucleotide catabolism.
2005-10-21 GO:0045980 negative regulation of nucleotide metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nucleotides.
2005-10-21 GO:0045849 negative regulation of nurse cell apoptotic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nurse cell apoptosis.
2005-10-21 GO:0042483 negative regulation of odontogenesis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation and development of a tooth or teeth.
2005-10-21 GO:0042486 negative regulation of odontogenesis of calcareous or chitinous tooth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation and development of a tooth, any hard calcareous or chitinous organ found in the mouth and used in feeding or procuring food, e.g. a mollusk or starfish tooth. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).
2005-10-21 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx, as in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2005-10-21 GO:0048715 negative regulation of oligodendrocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of oligodendrocyte differentiation.
2005-10-21 GO:0046621 negative regulation of organ growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of growth of an organ of an organism.
2005-10-21 GO:0044252 negative regulation of multicellular organismal metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2005-10-21 GO:0051241 negative regulation of multicellular organismal process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of an organismal physiological process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
2005-10-21 GO:0030279 negative regulation of ossification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of bone formation.
2005-10-21 GO:0045668 negative regulation of osteoblast differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of osteoblast differentiation.
2005-10-21 GO:0045671 negative regulation of osteoclast differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of osteoclast differentiation.
2005-10-21 GO:0042527 negative regulation of tyrosine phosphorylation of Stat6 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat6 protein.
2005-10-21 GO:0042530 negative regulation of tyrosine phosphorylation of Stat7 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat7 protein.
2005-10-21 GO:0051444 negative regulation of ubiquitin-protein transferase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-10-21 GO:0051442 negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity during the meiotic cell cycle.
2005-10-21 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity during the mitotic cell cycle.
2005-10-21 GO:0046889 positive regulation of lipid biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation of lipids from simpler components.
2005-10-21 GO:0050996 positive regulation of lipid catabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the breakdown of lipids into simpler components.
2005-10-21 GO:0045834 positive regulation of lipid metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving lipids.
2005-10-21 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of signaling in response to detection of lipopolysaccharide.
2005-10-21 GO:0050747 positive regulation of lipoprotein metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids.
2005-10-21 GO:0040017 positive regulation of locomotion Updated DEFINITION Any process that activates or increases the rate, frequency or extent of locomotion of an organism.
2005-10-21 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of low-density lipoprotein receptors.
2005-10-21 GO:0051349 positive regulation of lyase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
2005-10-21 GO:0051251 positive regulation of lymphocyte activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of lymphocyte activation.
2005-10-21 GO:0045621 positive regulation of lymphocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of lymphocyte differentiation.
2005-10-21 GO:0045651 positive regulation of macrophage differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of macrophage differentiation.
2005-10-21 GO:0048093 positive regulation of male pigmentation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of establishment of a pattern of pigment in males.
2005-10-21 GO:0043406 positive regulation of MAP kinase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of protein kinase activity.
2005-10-21 GO:0045632 negative regulation of mechanoreceptor differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mechanoreceptor differentiation.
2005-10-21 GO:0045653 negative regulation of megakaryocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of megakaryocyte differentiation.
2005-10-21 GO:0045835 negative regulation of meiotic nuclear division Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of meiosis.
2005-10-21 GO:0045128 negative regulation of reciprocal meiotic recombination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of recombination during meiosis.
2005-10-21 GO:0045635 negative regulation of melanocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of melanocyte differentiation.
2005-10-21 GO:0043410 positive regulation of MAPK cascade Updated DEFINITION Any process that activates or increases the rate, frequency or extent of signal transduction mediated by the MAPK cascade.
2005-10-21 GO:0043306 positive regulation of mast cell degranulation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mast cell degranulation.
2005-10-21 GO:0031496 positive regulation of mating type switching Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mating type switching.
2005-10-21 GO:0045633 positive regulation of mechanoreceptor differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mechanoreceptor differentiation.
2005-10-21 GO:0045654 positive regulation of megakaryocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of megakaryocyte differentiation.
2005-10-21 GO:0051025 negative regulation of immunoglobulin secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of immunoglobulins from a cell or group of cells.
2005-10-21 GO:0050728 negative regulation of inflammatory response Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the inflammatory response.
2005-10-21 GO:0045824 negative regulation of innate immune response Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the innate immune response.
2005-10-21 GO:0046676 negative regulation of insulin secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of insulin.
2005-10-21 GO:0045720 negative regulation of integrin biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of integrins.
2005-10-21 GO:0045355 negative regulation of interferon-alpha biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interferon-alpha.
2005-10-21 GO:0045358 negative regulation of interferon-beta biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interferon-beta.
2005-10-21 GO:0045077 negative regulation of interferon-gamma biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interferon-gamma.
2005-10-21 GO:0050723 negative regulation of interleukin-1 alpha biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-1 alpha.
2005-10-21 GO:0050712 negative regulation of interleukin-1 alpha secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of interleukin-1 alpha from a cell or group of cells.
2005-10-21 GO:0050724 negative regulation of interleukin-1 beta biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-1 beta.
2005-10-21 GO:0050713 negative regulation of interleukin-1 beta secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of interleukin-1 beta from a cell or group of cells.
2005-10-21 GO:0045361 negative regulation of interleukin-1 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-1.
2005-10-21 GO:0050711 negative regulation of interleukin-1 secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of interleukin-1 from a cell or group of cells.
2005-10-21 GO:0045081 negative regulation of interleukin-10 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-10.
2005-10-21 GO:0045364 negative regulation of interleukin-11 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-11.
2005-10-21 GO:0045083 negative regulation of interleukin-12 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-12.
2005-10-21 GO:0045367 negative regulation of interleukin-13 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-13.
2005-10-21 GO:0045370 negative regulation of interleukin-14 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-14.
2005-10-21 GO:0045373 negative regulation of interleukin-15 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-15.
2005-10-21 GO:0045376 negative regulation of interleukin-16 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-16.
2005-10-21 GO:0045379 negative regulation of interleukin-17 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-17.
2005-10-21 GO:0045382 negative regulation of interleukin-18 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-18.
2005-10-21 GO:0045385 negative regulation of interleukin-19 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-19.
2005-10-21 GO:0045085 negative regulation of interleukin-2 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-2.
2005-10-21 GO:0045388 negative regulation of interleukin-20 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-20.
2005-10-21 GO:0045391 negative regulation of interleukin-21 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-21.
2005-10-21 GO:0045394 negative regulation of interleukin-22 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-22.
2005-10-21 GO:0045397 negative regulation of interleukin-23 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-23.
2005-10-21 GO:0045532 negative regulation of interleukin-24 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-24.
2005-10-21 GO:0045533 negative regulation of interleukin-25 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-25.
2005-10-21 GO:0045534 negative regulation of interleukin-26 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-26.
2005-10-21 GO:0045535 negative regulation of interleukin-27 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-27.
2005-10-21 GO:0045400 negative regulation of interleukin-3 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-3.
2005-10-21 GO:0045403 negative regulation of interleukin-4 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-4.
2005-10-21 GO:0045406 negative regulation of interleukin-5 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-5.
2005-10-21 GO:0051548 negative regulation of keratinocyte migration Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of keratinocyte migration.
2005-10-21 GO:0035204 negative regulation of lamellocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
2005-10-21 GO:0045710 negative regulation of larval salivary gland boundary specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of salivary gland determination in a larval organism.
2005-10-21 GO:0050949 negative regulation of late stripe melanocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of late stripe melanocyte differentiation.
2005-10-21 GO:0048375 negative regulation of lateral mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lateral mesoderm cell fate determination.
2005-10-21 GO:0045401 positive regulation of interleukin-3 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-3.
2005-10-21 GO:0045404 positive regulation of interleukin-4 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-4.
2005-10-21 GO:0045407 positive regulation of interleukin-5 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-5.
2005-10-21 GO:0045410 positive regulation of interleukin-6 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-6.
2005-10-21 GO:0045413 positive regulation of interleukin-7 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-7.
2005-10-21 GO:0045416 positive regulation of interleukin-8 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-8.
2005-10-21 GO:0045419 positive regulation of interleukin-9 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-9.
2005-10-21 GO:0030844 positive regulation of intermediate filament depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of intermediate filament depolymerization.
2005-10-21 GO:0030841 positive regulation of intermediate filament polymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of intermediate filament polymerization.
2005-10-21 GO:0045826 obsolete positive regulation of intermediate filament polymerization and/or depolymerization Updated DEFINITION OBSOLETE. Any process that activates or increases the rate, frequency or extent of intermediate filament polymerization and/or depolymerization.
2005-10-21 GO:0045827 negative regulation of isoprenoid metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving isoprenoid.
2005-10-21 GO:0046888 negative regulation of hormone secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a hormone from a cell or group of cells.
2005-10-21 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of an I-kappaB kinase/NF-kappaB induced cascade.
2005-10-21 GO:0045571 negative regulation of imaginal disc growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of imaginal disc growth.
2005-10-21 GO:0050777 negative regulation of immune response Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
2005-10-21 GO:0045409 negative regulation of interleukin-6 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-6.
2005-10-21 GO:0045412 negative regulation of interleukin-7 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-7.
2005-10-21 GO:0045415 negative regulation of interleukin-8 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-8.
2005-10-21 GO:0045418 negative regulation of interleukin-9 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-9.
2005-10-21 GO:0030843 negative regulation of intermediate filament depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate filament depolymerization.
2005-10-21 GO:0030840 negative regulation of intermediate filament polymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate filament polymerization.
2005-10-21 GO:0045825 obsolete negative regulation of intermediate filament polymerization and/or depolymerization Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of intermediate filament polymerization and/or depolymerization.
2005-10-21 GO:0048396 negative regulation of intermediate mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate mesoderm cell fate determination.
2005-10-21 GO:0048401 negative regulation of intermediate mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate mesoderm cell fate specification.
2005-10-21 GO:0043271 negative regulation of ion transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of charged atoms or small charged molecules into, out of, within or between cells.
2005-10-21 GO:0031586 negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of the IP3 receptor.
2005-10-21 GO:0050943 negative regulation of iridophore differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of iridophore differentiation.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM minus-end F-actin capping activity
2005-10-21 GO:0045639 positive regulation of myeloid cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of myeloid cell differentiation.
2005-10-21 GO:0045663 positive regulation of myoblast differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of myoblast differentiation.
2005-10-21 GO:0045846 positive regulation of natural killer cell activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer cell activity.
2005-10-21 GO:0043323 positive regulation of natural killer cell degranulation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer cell degranulation.
2005-10-21 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer cell mediated cytotoxicity.
2005-10-21 GO:0050924 positive regulation of negative chemotaxis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM minus-end actin filament capping activity
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM pointed-end F-actin capping activity
2005-10-21 GO:0051694 pointed-end actin filament capping Added SYNONYM pointed-end actin capping activity
2005-10-21 GO:0051695 actin filament uncapping Added SYNONYM F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus end F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus end actin filament uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus-end F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM minus-end actin filament uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM pointed end F-actin uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM pointed end actin filament uncapping
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added SYNONYM pointed-end F-actin uncapping
2005-10-21 GO:0051016 barbed-end actin filament capping Deleted SYNONYM F-actin capping activity
2005-10-21 GO:0048629 trichome patterning Added SYNONYM trichome pattern formation
2005-10-21 GO:0048629 trichome patterning Added SYNONYM trichome spacing
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM barbed end F-actin uncapping
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM barbed end actin filament uncapping
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM plus end F-actin uncapping
2005-10-21 GO:0051638 barbed-end actin filament uncapping Added SYNONYM plus end actin filament uncapping
2005-10-21 GO:0051693 actin filament capping Added SYNONYM F-actin capping activity
2005-10-21 GO:0051693 actin filament capping Added SYNONYM actin capping activity
2005-10-21 GO:0048326 positive regulation of axial mesodermal cell fate determination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axial mesoderm cell fate determination.
2005-10-21 GO:0048330 positive regulation of axial mesodermal cell fate specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axial mesoderm cell fate specification.
2005-10-21 GO:0045773 positive regulation of axon extension Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axon extension.
2005-10-21 GO:0050772 positive regulation of axonogenesis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of axonogenesis.
2005-10-21 GO:0050871 positive regulation of B cell activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of B cell activation.
2005-10-21 GO:0045579 positive regulation of B cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of B cell differentiation.
2005-10-21 GO:0045836 positive regulation of meiotic nuclear division Updated DEFINITION Any process that activates or increases the rate, frequency or extent of meiosis.
2005-10-21 GO:0045636 positive regulation of melanocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of melanocyte differentiation.
2005-10-21 GO:0045838 positive regulation of membrane potential Updated DEFINITION Any process that activates or increases the rate, frequency or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2005-10-21 GO:0051044 positive regulation of membrane protein ectodomain proteolysis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of membrane protein ectodomain peptidolysis.
2005-10-21 GO:0043382 positive regulation of memory T cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of memory T cell differentiation.
2005-10-21 GO:0048336 positive regulation of mesodermal cell fate determination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mesoderm cell fate determination.
2005-10-21 GO:0048337 positive regulation of mesodermal cell fate specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mesoderm cell fate specification.
2005-10-21 GO:0009910 negative regulation of flower development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of flower development.
2005-10-21 GO:0046882 negative regulation of follicle-stimulating hormone secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of follicle-stimulating hormone.
2005-10-21 GO:0050753 negative regulation of fractalkine biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.
2005-10-21 GO:0045810 negative regulation of frizzled signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the frizzled signaling pathway.
2005-10-21 GO:0045812 negative regulation of Wnt signaling pathway, calcium modulating pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the frizzled-2 signaling pathway.
2005-10-21 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of G-protein coupled receptor protein signaling pathway activity.
2005-10-21 GO:0046644 negative regulation of gamma-delta T cell activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gamma-delta T cell activation.
2005-10-21 GO:0045587 negative regulation of gamma-delta T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gamma-delta T cell differentiation.
2005-10-21 GO:0046647 negative regulation of gamma-delta T cell proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gamma-delta T cell proliferation.
2005-10-21 GO:0009938 negative regulation of gibberellic acid mediated signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gibberellic acid mediated signaling activity.
2005-10-21 GO:0045686 negative regulation of glial cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of glia cell differentiation.
2005-10-21 GO:0045816 negative regulation of transcription from RNA polymerase II promoter, global Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of global transcription from an RNA polymerase II promoter.
2005-10-21 GO:0045721 negative regulation of gluconeogenesis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of gluconeogenesis.
2005-10-21 GO:0046325 negative regulation of glucose import Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
2005-10-21 GO:0046318 negative regulation of glucosylceramide biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of glucosylceramide.
2005-10-21 GO:0045719 negative regulation of glycogen biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of glycogen.
2005-10-21 GO:0045818 negative regulation of glycogen catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown into simpler components of glycogen.
2005-10-21 GO:0045820 negative regulation of glycolytic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of glycolysis.
2005-10-21 GO:0043002 negative regulation of Golgi to plasma membrane CFTR protein transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.
2005-10-21 GO:0042997 negative regulation of Golgi to plasma membrane protein transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the transport of proteins from the Golgi to the plasma membrane.
2005-10-21 GO:0048216 negative regulation of Golgi vesicle fusion to target membrane Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Golgi vesicle fusion to target membrane.
2005-10-21 GO:0030853 negative regulation of granulocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of granulocyte differentiation.
2005-10-21 GO:0045424 negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of granulocyte macrophage colony-stimulating factor.
2005-10-21 GO:0031283 negative regulation of guanylate cyclase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of guanylate cyclase activity.
2005-10-21 GO:0042636 negative regulation of hair cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
2005-10-21 GO:0045822 negative regulation of heart contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of heart contraction.
2005-10-21 GO:0045611 negative regulation of hemocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of hemocyte differentiation.
2005-10-21 GO:0046986 negative regulation of hemoglobin biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
2005-10-21 GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of hepatocyte growth factor.
2005-10-21 GO:0051617 negative regulation of histamine uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of histamine into a cell.
2005-10-21 GO:0050669 negative regulation of homocysteine metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving homocysteine.
2005-10-21 GO:0045348 positive regulation of MHC class II biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of MHC class II.
2005-10-21 GO:0031117 positive regulation of microtubule depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of microtubule depolymerization.
2005-10-21 GO:0031116 positive regulation of microtubule polymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of microtubule polymerization.
2005-10-21 GO:0031112 positive regulation of microtubule polymerization or depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of microtubule polymerization or depolymerization.
2005-10-21 GO:0045840 positive regulation of mitotic nuclear division Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mitosis.
2005-10-21 GO:0045931 positive regulation of mitotic cell cycle Updated DEFINITION Any process that activates or increases the rate, frequency or extent of progression through the mitotic cell cycle.
2005-10-21 GO:0045977 positive regulation of mitotic cell cycle, embryonic Updated DEFINITION Any process that activates or increases the rate, frequency or extent of progression through the embryonic mitotic cell cycle.
2005-10-21 GO:0046604 positive regulation of mitotic centrosome separation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of centrosome separation.
2005-10-21 GO:0045842 positive regulation of mitotic metaphase/anaphase transition Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the mitotic metaphase to anaphase transition.
2005-10-21 GO:0045951 positive regulation of mitotic recombination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of DNA recombination during mitosis.
2005-10-21 GO:0045657 positive regulation of monocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of monocyte differentiation.
2005-10-21 GO:0051515 positive regulation of monopolar cell growth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of monopolar cell growth, polarized growth from one end of a cell.
2005-10-21 GO:0031442 positive regulation of mRNA 3'-end processing Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mRNA 3'-end processing.
2005-10-21 GO:0031439 positive regulation of mRNA cleavage Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mRNA cleavage.
2005-10-21 GO:0050685 positive regulation of mRNA processing Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mRNA processing.
2005-10-21 GO:0051149 positive regulation of muscle cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of muscle cell differentiation.
2005-10-21 GO:0045933 positive regulation of muscle contraction Updated DEFINITION Any process that activates or increases the rate, frequency or extent of muscle contraction.
2005-10-21 GO:0031643 positive regulation of myelination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation of a myelin sheath around nerve axons.
2005-10-21 GO:0010187 negative regulation of seed germination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of seed germination.
2005-10-21 GO:0051283 negative regulation of sequestering of calcium ion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
2005-10-21 GO:0051612 negative regulation of serotonin uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of serotonin into a cell.
2005-10-21 GO:0045873 negative regulation of sevenless signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the sevenless signaling pathway.
2005-10-21 GO:0009968 negative regulation of signal transduction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signal transduction.
2005-10-21 GO:0009893 positive regulation of metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of chemical reactions involving a substance.
2005-10-21 GO:0045345 positive regulation of MHC class I biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of MHC class I.
2005-10-21 GO:0045565 negative regulation of TRAIL receptor 1 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.
2005-10-21 GO:0045623 negative regulation of T-helper cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T-helper cell differentiation.
2005-10-21 GO:0048239 negative regulation of DNA recombination at telomere Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of genetic recombination within the telomere.
2005-10-21 GO:0050760 negative regulation of thymidylate synthase biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of the enzyme thymidylate synthase.
2005-10-21 GO:0045751 negative regulation of Toll signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the Tl signaling pathway.
2005-10-21 GO:0045555 negative regulation of TRAIL biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of TRAIL, TNF-related apoptosis inducing ligand.
2005-10-21 GO:0051396 positive regulation of nerve growth factor receptor activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the activity of the nerve growth factor receptor.
2005-10-21 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the activity of the nerve growth factor receptor signaling pathway.
2005-10-21 GO:0050769 positive regulation of neurogenesis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neurogenesis, the origin and formation of neurons.
2005-10-21 GO:0045666 positive regulation of neuron differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neuron differentiation.
2005-10-21 GO:0031646 positive regulation of neurological system process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of a neurophysiological process.
2005-10-21 GO:0001956 positive regulation of neurotransmitter secretion Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the regulated release of a neurotransmitter.
2005-10-21 GO:0051590 positive regulation of neurotransmitter transport Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of a neurotransmitter into, out of, within or between cells.
2005-10-21 GO:0051582 positive regulation of neurotransmitter uptake Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of a neurotransmitter into a cell.
2005-10-21 GO:0043315 positive regulation of neutrophil degranulation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neutrophil degranulation.
2005-10-21 GO:0045660 positive regulation of neutrophil differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of neutrophil differentiation.
2005-10-21 GO:0042346 positive regulation of NF-kappaB import into nucleus Updated DEFINITION Any process that activates or increases the rate, frequency or extent of transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
2005-10-21 GO:0051533 positive regulation of NFAT protein import into nucleus Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-10-21 GO:0045429 positive regulation of nitric oxide biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of nitric oxide.
2005-10-21 GO:0045908 negative regulation of vasodilation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of vasodilation.
2005-10-21 GO:0045071 negative regulation of viral genome replication Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of viral genome replication.
2005-10-21 GO:0048525 negative regulation of viral process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.
2005-10-21 GO:0046597 negative regulation of viral entry into host cell Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of virus particles into the cell.
2005-10-21 GO:0046137 negative regulation of vitamin metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
2005-10-21 GO:0040027 negative regulation of vulval development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of development of the vulva, as in, but not restricted to, the roundworms (Nematoda, ncbi_taxonomy_id:6231).
2005-10-21 GO:0030178 negative regulation of Wnt signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Wnt receptor signaling pathway activity.
2005-10-21 GO:0050944 negative regulation of xanthophore differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of xanthophore differentiation.
2005-10-21 GO:0051694 pointed-end actin filament capping Added DEFINITION The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
2005-10-21 GO:0051696 pointed-end actin filament uncapping Added DEFINITION The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
2005-10-21 GO:0010116 positive regulation of abscisic acid biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of abscisic acid biosynthesis.
2005-10-21 GO:0009789 positive regulation of abscisic acid-activated signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of abscisic acid mediated signal transduction.
2005-10-21 GO:0045754 positive regulation of acetate catabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the breakdown into simpler components of acetate.
2005-10-21 GO:0051633 positive regulation of acetylcholine uptake Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of acetylcholine into a cell.
2005-10-21 GO:0030836 positive regulation of actin filament depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of actin depolymerization.
2005-10-21 GO:0030838 positive regulation of actin filament polymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of actin polymerization.
2005-10-21 GO:0051127 positive regulation of actin nucleation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
2005-10-21 GO:0045758 obsolete positive regulation of actin polymerization and/or depolymerization Updated DEFINITION OBSOLETE. Any process that activates or increases the rate, frequency or extent of actin polymerization and/or depolymerization.
2005-10-21 GO:0045760 positive regulation of action potential Updated DEFINITION Any process that activates or increases the rate, frequency or extent of action potential creation, propagation or termination.
2005-10-21 GO:0045762 positive regulation of adenylate cyclase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of adenylate cyclase activity.
2005-10-21 GO:0051461 positive regulation of corticotropin secretion Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the regulated release of adrenocorticotropin hormone from a cell or group of cells.
2005-10-21 GO:0048084 positive regulation of adult chitin-containing cuticle pigmentation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
2005-10-21 GO:0045711 positive regulation of adult salivary gland boundary specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of salivary gland determination in an adult organism.
2005-10-21 GO:0046635 positive regulation of alpha-beta T cell activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of alpha-beta T cell activation.
2005-10-21 GO:0046638 positive regulation of alpha-beta T cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of alpha-beta T cell differentiation.
2005-10-21 GO:0046641 positive regulation of alpha-beta T cell proliferation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of alpha-beta T cell proliferation.
2005-10-21 GO:0045764 positive regulation of cellular amino acid metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving amino acid.
2005-10-21 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the biosynthesis of amyloid precursor protein (APP), the precursor of beta-amyloid.
2005-10-21 GO:0031542 positive regulation of anthocyanin biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation of anthocyanins from simpler components.
2005-10-21 GO:0031539 positive regulation of anthocyanin metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of chemical reactions involving anthocyanins.
2005-10-21 GO:0045768 obsolete positive regulation of anti-apoptosis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of anti-apoptosis.
2005-10-21 GO:0001815 positive regulation of antibody-dependent cellular cytotoxicity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of antibody-dependent cellular cytotoxicity.
2005-10-21 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
2005-10-21 GO:0045690 positive regulation of antipodal cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of antipodal cell differentiation.
2005-10-21 GO:0043065 positive regulation of apoptotic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of cell death by apoptosis.
2005-10-21 GO:0048711 positive regulation of astrocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of astrocyte differentiation.
2005-10-21 GO:0045770 positive regulation of asymmetric cell division Updated DEFINITION Any process that activates or increases the rate, frequency or extent of asymmetric cell division.
2005-10-21 GO:0045609 positive regulation of auditory receptor cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of auditory hair cell differentiation.
2005-10-21 GO:0045698 negative regulation of synergid differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synergid cell differentiation.
2005-10-21 GO:0010113 negative regulation of systemic acquired resistance Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of systemic acquired resistance.
2005-10-21 GO:0050868 negative regulation of T cell activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T cell activation.
2005-10-21 GO:0045581 negative regulation of T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T cell differentiation.
2005-10-21 GO:0050860 negative regulation of T cell receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
2005-10-21 GO:0045626 negative regulation of T-helper 1 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T-helper 1 cell differentiation.
2005-10-21 GO:0045629 negative regulation of T-helper 2 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of T-helper 2 cell differentiation.
2005-10-21 GO:0045935 positive regulation of nucleobase-containing compound metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nucleobases, nucleosides, nucleotides and nucleic acids.
2005-10-21 GO:0046824 positive regulation of nucleocytoplasmic transport Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of substances between the nucleus and the cytoplasm.
2005-10-21 GO:0045979 positive regulation of nucleoside metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nucleosides.
2005-10-21 GO:0030810 positive regulation of nucleotide biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nucleotide biosynthesis.
2005-10-21 GO:0030813 positive regulation of nucleotide catabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nucleotide catabolism.
2005-10-21 GO:0045981 positive regulation of nucleotide metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nucleotides.
2005-10-21 GO:0045850 positive regulation of nurse cell apoptotic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nurse cell apoptosis.
2005-10-21 GO:0042482 positive regulation of odontogenesis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation and development of a tooth or teeth.
2005-10-21 GO:0042485 positive regulation of odontogenesis of calcareous or chitinous tooth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation and development of a tooth, any hard calcareous or chitinous organ found in the mouth and used in feeding or procuring food, e.g. a mollusk or starfish tooth. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).
2005-10-21 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. As in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2005-10-21 GO:0048714 positive regulation of oligodendrocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of oligodendrocyte differentiation.
2005-10-21 GO:0046622 positive regulation of organ growth Updated DEFINITION Any process that activates or increases the rate, frequency or extent of growth of an organ of an organism.
2005-10-21 GO:0044253 positive regulation of multicellular organismal metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2005-10-21 GO:0051240 positive regulation of multicellular organismal process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of an organismal physiological process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
2005-10-21 GO:0046012 positive regulation of oskar mRNA translation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of oskar mRNA translation.
2005-10-21 GO:0045778 positive regulation of ossification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of bone formation.
2005-10-21 GO:0045669 positive regulation of osteoblast differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of osteoblast differentiation.
2005-10-21 GO:0045672 positive regulation of osteoclast differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of osteoclast differentiation.
2005-10-21 GO:0051353 positive regulation of oxidoreductase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
2005-10-21 GO:0048346 positive regulation of paraxial mesodermal cell fate determination Updated DEFINITION Any process that activates or increases the rate, frequency or extent of paraxial mesoderm cell fate determination.
2005-10-21 GO:0048350 positive regulation of paraxial mesodermal cell fate specification Updated DEFINITION Any process that activates or increases the rate, frequency or extent of paraxial mesoderm cell fate specification.
2005-10-21 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the phosphorylation of peptidyl-tyrosine.
2005-10-21 GO:0050766 positive regulation of phagocytosis Updated DEFINITION Any process that activates or increases the rate, frequency or extent of phagocytosis.
2005-10-21 GO:0045937 positive regulation of phosphate metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving phosphates.
2005-10-21 GO:0045949 positive regulation of phosphorus utilization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of phosphorus utilization.
2005-10-21 GO:0042327 positive regulation of phosphorylation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of addition of phosphoric groups to a molecule.
2005-10-21 GO:0046534 positive regulation of photoreceptor cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of photoreceptor differentiation.
2005-10-21 GO:0045675 positive regulation of photoreceptor differentiation (sensu Endopterygota) Updated DEFINITION Any process that activates or increases the rate, frequency or extent of photoreceptor differentiation. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2005-10-21 GO:0043119 positive regulation of physiological process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2005-10-21 GO:0050942 positive regulation of pigment cell differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of pigment cell differentiation.
2005-10-21 GO:0045615 positive regulation of plasmatocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of plasmatocyte differentiation.
2005-10-21 GO:0050709 negative regulation of protein secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a protein from a cell or group of cells.
2005-10-21 GO:0051224 negative regulation of protein transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a protein into, out of, within or between cells.
2005-10-21 GO:0031397 negative regulation of protein ubiquitination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the addition of ubiquitin moieties to a protein.
2005-10-21 GO:0045861 negative regulation of proteolysis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the hydrolysis of a peptide bond or bonds within a protein.
2005-10-21 GO:0031273 negative regulation of pseudopodium assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the assembly of pseudopodia.
2005-10-21 GO:0045863 negative regulation of pteridine metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving pteridine.
2005-10-21 GO:0045982 negative regulation of purine nucleobase metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving purine bases.
2005-10-21 GO:0045984 negative regulation of pyrimidine nucleobase metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving pyrimidine bases.
2005-10-21 GO:0045677 negative regulation of R7 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of R7 differentiation.
2005-10-21 GO:0045680 negative regulation of R8 cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of R8 differentiation.
2005-10-21 GO:0046580 negative regulation of Ras protein signal transduction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of Ras protein signal transduction.
2005-10-21 GO:0048261 negative regulation of receptor-mediated endocytosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
2005-10-21 GO:0000020 obsolete negative regulation of recombination within rDNA repeats Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.
2005-10-21 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
2005-10-21 GO:0048585 negative regulation of response to stimulus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
2005-10-21 GO:0046673 negative regulation of compound eye retinal cell programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of programmed cell death that occurs in the retina. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2005-10-21 GO:0046671 negative regulation of retinal cell programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of programmed cell death that occurs in the retina.
2005-10-21 GO:0048387 negative regulation of retinoic acid receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of retinoic acid receptor signaling pathway activity.
2005-10-21 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of retroviral genome replication.
2005-10-21 GO:0045871 negative regulation of rhodopsin gene expression Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of rhodopsin gene activity.
2005-10-21 GO:0046832 negative regulation of RNA export from nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of RNA from the nucleus into the cytoplasm.
2005-10-21 GO:0046829 negative regulation of RNA import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the movement of RNA from the cytoplasm into the nucleus.
2005-10-21 GO:0051253 negative regulation of RNA metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving RNA.
2005-10-21 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of S phase of mitotic cell cycle activity.
2005-10-21 GO:0045705 negative regulation of salivary gland boundary specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of salivary gland determination.
2005-10-21 GO:0051048 negative regulation of secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a substance from a cell or group of cells.
2005-10-21 GO:0042177 negative regulation of protein catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown into simpler components of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2005-10-21 GO:0043242 negative regulation of protein complex disassembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
2005-10-21 GO:0046826 negative regulation of protein export from nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of proteins from the nucleus into the cytoplasm.
2005-10-21 GO:0042308 negative regulation of protein import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the movement of proteins from the cytoplasm into the nucleus.
2005-10-21 GO:0006469 negative regulation of protein kinase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of protein kinase activity.
2005-10-21 GO:0051248 negative regulation of protein metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of chemical reactions involving a protein.
2005-10-21 GO:0031400 negative regulation of protein modification process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the covalent alteration of one or more amino acid residues within a protein.
2005-10-21 GO:0045567 negative regulation of TRAIL receptor 2 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.
2005-10-21 GO:0045563 negative regulation of TRAIL receptor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of the TRAIL (TNF-related apoptosis inducing ligand) receptor.
2005-10-21 GO:0016481 negative regulation of transcription Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription.
2005-10-21 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
2005-10-21 GO:0042992 negative regulation of transcription factor import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the movement of a transcription factor from the cytoplasm to the nucleus.
2005-10-21 GO:0016479 negative regulation of transcription from RNA polymerase I promoter Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase I promoter.
2005-10-21 GO:0007069 negative regulation of transcription from RNA polymerase I promoter during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase I promoter during mitosis.
2005-10-21 GO:0000122 negative regulation of transcription from RNA polymerase II promoter Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase II promoter.
2005-10-21 GO:0007070 negative regulation of transcription from RNA polymerase II promoter during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase II promoter during mitosis.
2005-10-21 GO:0016480 negative regulation of transcription from RNA polymerase III promoter Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase III promoter.
2005-10-21 GO:0007071 negative regulation of transcription from RNA polymerase III promoter during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription from an RNA polymerase III promoter during mitosis.
2005-10-21 GO:0006340 obsolete negative regulation of transcription of homeotic gene (Polycomb group) Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of transcription of homeotic genes of the Polycomb group.
2005-10-21 GO:0045891 obsolete negative regulation of transcription of homeotic gene (trithorax group) Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of transcription of homeotic genes of the trithorax group.
2005-10-21 GO:0045892 negative regulation of transcription, DNA-templated Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of DNA-dependent transcription.
2005-10-21 GO:0051038 negative regulation of transcription involved in meiotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription during meiosis.
2005-10-21 GO:0007068 negative regulation of transcription during mitosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcription during mitosis.
2005-10-21 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of transcriptional preinitiation complex formation.
2005-10-21 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of any TGFbeta receptor signaling pathway.
2005-10-21 GO:0045900 negative regulation of translational elongation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of translational elongation.
2005-10-21 GO:0045902 negative regulation of translational fidelity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of activities to ensure translational fidelity.
2005-10-21 GO:0045947 negative regulation of translational initiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of translational initiation.
2005-10-21 GO:0045904 negative regulation of translational termination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of translational termination.
2005-10-21 GO:0051051 negative regulation of transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells.
2005-10-21 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of biosynthesis of tumor necrosis factor-alpha, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
2005-10-21 GO:0043018 negative regulation of lymphotoxin A biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of the cytokine tumor necrosis factor-beta.
2005-10-21 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
2005-10-21 GO:0042512 negative regulation of tyrosine phosphorylation of Stat1 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat1 protein.
2005-10-21 GO:0042514 negative regulation of tyrosine phosphorylation of Stat2 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat2 protein.
2005-10-21 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat3 protein.
2005-10-21 GO:0042521 negative regulation of tyrosine phosphorylation of Stat4 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat4 protein.
2005-10-21 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat5 protein.
2005-10-21 GO:0045875 negative regulation of sister chromatid cohesion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sister chromatid cohesion.
2005-10-21 GO:0048642 negative regulation of skeletal muscle tissue development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle development.
2005-10-21 GO:0048744 negative regulation of skeletal muscle fiber development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle fiber development.
2005-10-21 GO:0048632 negative regulation of skeletal muscle tissue growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle growth.
2005-10-21 GO:0043417 negative regulation of skeletal muscle tissue regeneration Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of skeletal muscle regeneration.
2005-10-21 GO:0051151 negative regulation of smooth muscle cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of smooth muscle cell differentiation.
2005-10-21 GO:0045986 negative regulation of smooth muscle contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of smooth muscle contraction.
2005-10-21 GO:0045879 negative regulation of smoothened signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of smoothened signaling.
2005-10-21 GO:0045701 negative regulation of spermatid nuclear differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of spermatid nuclear differentiation.
2005-10-21 GO:0042174 negative regulation of sporulation resulting in formation of a cellular spore Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sporulation.
2005-10-21 GO:0048688 negative regulation of sprouting of injured axon Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sprouting of an injured axon.
2005-10-21 GO:0031286 negative regulation of sorocarp stalk cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of stalk cell differentiation.
2005-10-21 GO:0045939 negative regulation of steroid metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving steroids.
2005-10-21 GO:0051497 negative regulation of stress fiber assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
2005-10-21 GO:0031447 negative regulation of fast-twitch skeletal muscle fiber contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated fast muscle contraction.
2005-10-21 GO:0031453 positive regulation of heterochromatin assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated mixed muscle contraction.
2005-10-21 GO:0051154 negative regulation of striated muscle cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated muscle cell differentiation.
2005-10-21 GO:0045988 negative regulation of striated muscle contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated muscle contraction.
2005-10-21 GO:0045843 negative regulation of striated muscle tissue development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated muscle development.
2005-10-21 GO:0031450 negative regulation of slow-twitch skeletal muscle fiber contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of striated slow muscle contraction.
2005-10-21 GO:0051175 negative regulation of sulfur metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving sulfur or compounds containing sulfur.
2005-10-21 GO:0045882 negative regulation of sulfur utilization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of sulfur utilization.
2005-10-21 GO:0008634 obsolete negative regulation of survival gene product expression Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of survival gene product activity; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.
2005-10-21 GO:0045886 negative regulation of synaptic growth at neuromuscular junction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synaptic growth at neuromuscular junction.
2005-10-21 GO:0050805 negative regulation of synaptic transmission Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2005-10-21 GO:0031631 negative regulation of synaptic vesicle fusion to presynaptic membrane Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of synaptic vesicle fusion to the presynaptic membrane.
2005-10-21 GO:0051511 negative regulation of unidimensional cell growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of unidimensional cell growth, the process by which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
2005-10-21 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of vascular endothelial growth factor receptor signaling pathway activity.
2005-10-21 GO:0045906 negative regulation of vasoconstriction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of vasoconstriction.
2005-10-21 GO:0051173 positive regulation of nitrogen compound metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving nitrogen or nitrogenous compounds.
2005-10-21 GO:0045848 positive regulation of nitrogen utilization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of nitrogen utilization.
2005-10-21 GO:0051135 positive regulation of NK T cell activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of natural killer T cell activation.
2005-10-21 GO:0051138 positive regulation of NK T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell differentiation.
2005-10-21 GO:0051142 positive regulation of NK T cell proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell proliferation.
2005-10-21 GO:0043071 positive regulation of non-apoptotic programmed cell death Updated DEFINITION Any process that activates or increases the rate, frequency or extent of non-apoptotic programmed cell death, cell death resulting from activation of endogenous cellular processes, by a mechanism other than apoptosis.
2005-10-21 GO:0051623 positive regulation of norepinephrine uptake Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the directed movement of norepinephrine into a cell.
2005-10-21 GO:0045747 positive regulation of Notch signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the Notch signaling pathway.
2005-10-21 GO:0048347 negative regulation of paraxial mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of paraxial mesoderm cell fate determination.
2005-10-21 GO:0048351 negative regulation of paraxial mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of paraxial mesoderm cell fate specification.
2005-10-21 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the phosphorylation of peptidyl-tyrosine.
2005-10-21 GO:0050765 negative regulation of phagocytosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of phagocytosis.
2005-10-21 GO:0045936 negative regulation of phosphate metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving phosphates.
2005-10-21 GO:0045942 negative regulation of phosphorus utilization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of phosphorus utilization.
2005-10-21 GO:0046533 negative regulation of photoreceptor cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of photoreceptor differentiation.
2005-10-21 GO:0045674 negative regulation of photoreceptor differentiation (sensu Endopterygota) Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of photoreceptor differentiation. As in, but not restricted to, the Holometabola (Endopterygota, ncbi_taxonomy_id:33392).
2005-10-21 GO:0043155 negative regulation of photosynthesis, light reaction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the light-dependent reaction of photosynthesis.
2005-10-21 GO:0043118 negative regulation of physiological process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2005-10-21 GO:0050941 negative regulation of pigment cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of pigment cell differentiation.
2005-10-21 GO:0048550 negative regulation of pinocytosis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of pinocytosis. Pinocytosis is the process whereby cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
2005-10-21 GO:0045614 negative regulation of plasmatocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of plasmatocyte differentiation.
2005-10-21 GO:0030861 negative regulation of polarized epithelial cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of polarized epithelial cell differentiation.
2005-10-21 GO:0045855 negative regulation of pole plasm oskar mRNA localization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the processes by which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
2005-10-21 GO:0050928 negative regulation of positive chemotaxis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
2005-10-21 GO:0048581 negative regulation of post-embryonic development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
2005-10-21 GO:0045837 negative regulation of membrane potential Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2005-10-21 GO:0051045 negative regulation of membrane protein ectodomain proteolysis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of membrane protein ectodomain proteolysis.
2005-10-21 GO:0048335 negative regulation of mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mesoderm cell fate determination.
2005-10-21 GO:0042662 negative regulation of mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mesoderm cell fate specification.
2005-10-21 GO:0009892 negative regulation of metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of chemical reactions involving a substance.
2005-10-21 GO:0048553 negative regulation of metalloenzyme activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.
2005-10-21 GO:0045344 negative regulation of MHC class I biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of MHC class I.
2005-10-21 GO:0045347 negative regulation of MHC class II biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of MHC class II.
2005-10-21 GO:0007026 negative regulation of microtubule depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-10-21 GO:0031115 negative regulation of microtubule polymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization.
2005-10-21 GO:0031111 negative regulation of microtubule polymerization or depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of microtubule polymerization or depolymerization.
2005-10-21 GO:0045839 negative regulation of mitotic nuclear division Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mitosis.
2005-10-21 GO:0046603 negative regulation of mitotic centrosome separation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of centrosome separation.
2005-10-21 GO:0045841 negative regulation of mitotic metaphase/anaphase transition Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the mitotic metaphase to anaphase transition.
2005-10-21 GO:0045656 negative regulation of monocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of monocyte differentiation.
2005-10-21 GO:0051514 negative regulation of monopolar cell growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of monopolar cell growth, polarized growth from one end of a cell.
2005-10-21 GO:0031441 negative regulation of mRNA 3'-end processing Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mRNA 3'-end processing.
2005-10-21 GO:0031438 negative regulation of mRNA cleavage Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mRNA cleavage.
2005-10-21 GO:0050686 negative regulation of mRNA processing Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mRNA processing.
2005-10-21 GO:0051148 negative regulation of muscle cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of muscle cell differentiation.
2005-10-21 GO:0045932 negative regulation of muscle contraction Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of muscle contraction.
2005-10-21 GO:0048635 negative regulation of muscle organ development Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of muscle development.
2005-10-21 GO:0031642 negative regulation of myelination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation of a myelin sheath around nerve axons.
2005-10-21 GO:0045638 negative regulation of myeloid cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of myeloid cell differentiation.
2005-10-21 GO:0045856 positive regulation of pole plasm oskar mRNA localization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the processes by which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
2005-10-21 GO:0043267 negative regulation of potassium ion transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of potassium ions (K+) into, out of, within or between cells.
2005-10-21 GO:0043069 negative regulation of programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
2005-10-21 GO:0045786 negative regulation of cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the cell cycle.
2005-10-21 GO:0045976 negative regulation of mitotic cell cycle, embryonic Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the embryonic mitotic cell cycle.
2005-10-21 GO:0051447 negative regulation of meiotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the meiotic cell cycle.
2005-10-21 GO:0045930 negative regulation of mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the mitotic cell cycle.
2005-10-21 GO:0046001 negative regulation of preblastoderm mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the preblastoderm mitotic cell cycle.
2005-10-21 GO:0046003 negative regulation of syncytial blastoderm mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of progression through the syncytial blastoderm mitotic cell cycle.
2005-10-21 GO:0031393 negative regulation of prostaglandin biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of prostaglandin biosynthesis.
2005-10-21 GO:0051201 negative regulation of prosthetic group metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions of a prosthetic group.
2005-10-21 GO:0017148 negative regulation of translation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of proteins.
2005-10-21 GO:0048380 negative regulation of lateral mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lateral mesoderm cell fate specification.
2005-10-21 GO:0031276 negative regulation of lateral pseudopodium assembly Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the assembly of pseudopodia from the lateral side of the cell.
2005-10-21 GO:0045831 negative regulation of light-activated channel activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of light-activated channel activity.
2005-10-21 GO:0051055 negative regulation of lipid biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of lipids.
2005-10-21 GO:0050995 negative regulation of lipid catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the breakdown of lipids into simpler components.
2005-10-21 GO:0045833 negative regulation of lipid metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving lipids.
2005-10-21 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signaling in response to detection of lipopolysaccharide.
2005-10-21 GO:0050748 negative regulation of lipoprotein metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids.
2005-10-21 GO:0040013 negative regulation of locomotion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of locomotion of an organism.
2005-10-21 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of low-density lipoprotein receptors.
2005-10-21 GO:0051250 negative regulation of lymphocyte activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lymphocyte activation.
2005-10-21 GO:0045620 negative regulation of lymphocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lymphocyte differentiation.
2005-10-21 GO:0016242 negative regulation of macroautophagy Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of macroautophagy.
2005-10-21 GO:0043031 negative regulation of macrophage activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of macrophage activation.
2005-10-21 GO:0045650 negative regulation of macrophage differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of macrophage differentiation.
2005-10-21 GO:0048092 negative regulation of male pigmentation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of establishment of a pattern of pigment in males.
2005-10-21 GO:0043407 negative regulation of MAP kinase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of MAPK activity.
2005-10-21 GO:0043409 negative regulation of MAPK cascade Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of signal transduction mediated by the MAPKKK cascade.
2005-10-21 GO:0031495 negative regulation of mating type switching Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mating type switching.
2005-10-21 GO:0045662 negative regulation of myoblast differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of myoblast differentiation.
2005-10-21 GO:0030102 negative regulation of natural killer cell activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer cell activity.
2005-10-21 GO:0050925 negative regulation of negative chemotaxis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
2005-10-21 GO:0051395 negative regulation of nerve growth factor receptor activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of the nerve growth factor receptor.
2005-10-21 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of the nerve growth factor receptor signaling pathway.
2005-10-21 GO:0007406 negative regulation of neuroblast proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the proliferation of neuroblasts.
2005-10-21 GO:0050768 negative regulation of neurogenesis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of neurogenesis, the origin and formation of neurons.
2005-10-21 GO:0045665 negative regulation of neuron differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of neuron differentiation.
2005-10-21 GO:0031645 negative regulation of neurological system process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of a neurophysiological process.
2005-10-21 GO:0046929 negative regulation of neurotransmitter secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a neurotransmitter.
2005-10-21 GO:0051589 negative regulation of neurotransmitter transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a neurotransmitter into, out of, within or between cells.
2005-10-21 GO:0051581 negative regulation of neurotransmitter uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of a neurotransmitter into a cell.
2005-10-21 GO:0045659 negative regulation of neutrophil differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of neutrophil differentiation.
2005-10-21 GO:0042347 negative regulation of NF-kappaB import into nucleus Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
2005-10-21 GO:0045019 negative regulation of nitric oxide biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of nitric oxide.
2005-10-21 GO:0051172 negative regulation of nitrogen compound metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nitrogen or nitrogenous compounds.
2005-10-21 GO:0045847 negative regulation of nitrogen utilization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nitrogen utilization.
2005-10-21 GO:0051134 negative regulation of NK T cell activation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell activation.
2005-10-21 GO:0051137 negative regulation of NK T cell differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell differentiation.
2005-10-21 GO:0051141 negative regulation of NK T cell proliferation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of natural killer T cell proliferation.
2005-10-21 GO:0043072 negative regulation of non-apoptotic programmed cell death Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of non-apoptotic programmed cell death, cell death resulting from activation of endogenous cellular processes, by a mechanism other than apoptosis.
2005-10-21 GO:0051622 negative regulation of norepinephrine uptake Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of norepinephrine into a cell.
2005-10-21 GO:0045746 negative regulation of Notch signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the Notch signaling pathway.
2005-10-21 GO:0045934 negative regulation of nucleobase-containing compound metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nucleobases, nucleosides, nucleotides and nucleic acids.
2005-10-21 GO:0046823 negative regulation of nucleocytoplasmic transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of substances between the cytoplasm and the nucleus.
2005-10-21 GO:0045978 negative regulation of nucleoside metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nucleosides.
2005-10-21 GO:0030809 negative regulation of nucleotide biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nucleotide biosynthesis.
2005-10-21 GO:0030812 negative regulation of nucleotide catabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nucleotide catabolism.
2005-10-21 GO:0045980 negative regulation of nucleotide metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving nucleotides.
2005-10-21 GO:0045849 negative regulation of nurse cell apoptotic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of nurse cell apoptosis.
2005-10-21 GO:0042483 negative regulation of odontogenesis Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation and development of a tooth or teeth.
2005-10-21 GO:0042486 negative regulation of odontogenesis of calcareous or chitinous tooth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation and development of a tooth, any hard calcareous or chitinous organ found in the mouth and used in feeding or procuring food, e.g. a mollusk or starfish tooth. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).
2005-10-21 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx, as in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742).
2005-10-21 GO:0048715 negative regulation of oligodendrocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of oligodendrocyte differentiation.
2005-10-21 GO:0046621 negative regulation of organ growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of growth of an organ of an organism.
2005-10-21 GO:0044252 negative regulation of multicellular organismal metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2005-10-21 GO:0051241 negative regulation of multicellular organismal process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of an organismal physiological process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
2005-10-21 GO:0030279 negative regulation of ossification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of bone formation.
2005-10-21 GO:0045668 negative regulation of osteoblast differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of osteoblast differentiation.
2005-10-21 GO:0045671 negative regulation of osteoclast differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of osteoclast differentiation.
2005-10-21 GO:0042527 negative regulation of tyrosine phosphorylation of Stat6 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat6 protein.
2005-10-21 GO:0042530 negative regulation of tyrosine phosphorylation of Stat7 protein Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the introduction of a phosphoric group to a tyrosine residue of a Stat7 protein.
2005-10-21 GO:0051444 negative regulation of ubiquitin-protein transferase activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
2005-10-21 GO:0051442 negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity during the meiotic cell cycle.
2005-10-21 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of ubiquitin ligase activity during the mitotic cell cycle.
2005-10-21 GO:0046889 positive regulation of lipid biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation of lipids from simpler components.
2005-10-21 GO:0050996 positive regulation of lipid catabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the breakdown of lipids into simpler components.
2005-10-21 GO:0045834 positive regulation of lipid metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving lipids.
2005-10-21 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway Updated DEFINITION Any process that activates or increases the rate, frequency or extent of signaling in response to detection of lipopolysaccharide.
2005-10-21 GO:0050747 positive regulation of lipoprotein metabolic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the chemical reactions involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids.
2005-10-21 GO:0040017 positive regulation of locomotion Updated DEFINITION Any process that activates or increases the rate, frequency or extent of locomotion of an organism.
2005-10-21 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of low-density lipoprotein receptors.
2005-10-21 GO:0051349 positive regulation of lyase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
2005-10-21 GO:0051251 positive regulation of lymphocyte activation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of lymphocyte activation.
2005-10-21 GO:0045621 positive regulation of lymphocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of lymphocyte differentiation.
2005-10-21 GO:0045651 positive regulation of macrophage differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of macrophage differentiation.
2005-10-21 GO:0048093 positive regulation of male pigmentation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of establishment of a pattern of pigment in males.
2005-10-21 GO:0043406 positive regulation of MAP kinase activity Updated DEFINITION Any process that activates or increases the rate, frequency or extent of protein kinase activity.
2005-10-21 GO:0045632 negative regulation of mechanoreceptor differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of mechanoreceptor differentiation.
2005-10-21 GO:0045653 negative regulation of megakaryocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of megakaryocyte differentiation.
2005-10-21 GO:0045835 negative regulation of meiotic nuclear division Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of meiosis.
2005-10-21 GO:0045128 negative regulation of reciprocal meiotic recombination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of recombination during meiosis.
2005-10-21 GO:0045635 negative regulation of melanocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of melanocyte differentiation.
2005-10-21 GO:0043410 positive regulation of MAPK cascade Updated DEFINITION Any process that activates or increases the rate, frequency or extent of signal transduction mediated by the MAPK cascade.
2005-10-21 GO:0043306 positive regulation of mast cell degranulation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mast cell degranulation.
2005-10-21 GO:0031496 positive regulation of mating type switching Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mating type switching.
2005-10-21 GO:0045633 positive regulation of mechanoreceptor differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of mechanoreceptor differentiation.
2005-10-21 GO:0045654 positive regulation of megakaryocyte differentiation Updated DEFINITION Any process that activates or increases the rate, frequency or extent of megakaryocyte differentiation.
2005-10-21 GO:0051025 negative regulation of immunoglobulin secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of immunoglobulins from a cell or group of cells.
2005-10-21 GO:0050728 negative regulation of inflammatory response Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the inflammatory response.
2005-10-21 GO:0045824 negative regulation of innate immune response Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the innate immune response.
2005-10-21 GO:0046676 negative regulation of insulin secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of insulin.
2005-10-21 GO:0045720 negative regulation of integrin biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of integrins.
2005-10-21 GO:0045355 negative regulation of interferon-alpha biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interferon-alpha.
2005-10-21 GO:0045358 negative regulation of interferon-beta biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interferon-beta.
2005-10-21 GO:0045077 negative regulation of interferon-gamma biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interferon-gamma.
2005-10-21 GO:0050723 negative regulation of interleukin-1 alpha biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-1 alpha.
2005-10-21 GO:0050712 negative regulation of interleukin-1 alpha secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of interleukin-1 alpha from a cell or group of cells.
2005-10-21 GO:0050724 negative regulation of interleukin-1 beta biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-1 beta.
2005-10-21 GO:0050713 negative regulation of interleukin-1 beta secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of interleukin-1 beta from a cell or group of cells.
2005-10-21 GO:0045361 negative regulation of interleukin-1 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-1.
2005-10-21 GO:0050711 negative regulation of interleukin-1 secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of interleukin-1 from a cell or group of cells.
2005-10-21 GO:0045081 negative regulation of interleukin-10 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-10.
2005-10-21 GO:0045364 negative regulation of interleukin-11 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-11.
2005-10-21 GO:0045083 negative regulation of interleukin-12 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-12.
2005-10-21 GO:0045367 negative regulation of interleukin-13 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-13.
2005-10-21 GO:0045370 negative regulation of interleukin-14 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-14.
2005-10-21 GO:0045373 negative regulation of interleukin-15 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-15.
2005-10-21 GO:0045376 negative regulation of interleukin-16 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-16.
2005-10-21 GO:0045379 negative regulation of interleukin-17 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-17.
2005-10-21 GO:0045382 negative regulation of interleukin-18 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-18.
2005-10-21 GO:0045385 negative regulation of interleukin-19 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-19.
2005-10-21 GO:0045085 negative regulation of interleukin-2 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-2.
2005-10-21 GO:0045388 negative regulation of interleukin-20 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-20.
2005-10-21 GO:0045391 negative regulation of interleukin-21 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-21.
2005-10-21 GO:0045394 negative regulation of interleukin-22 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-22.
2005-10-21 GO:0045397 negative regulation of interleukin-23 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-23.
2005-10-21 GO:0045532 negative regulation of interleukin-24 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-24.
2005-10-21 GO:0045533 negative regulation of interleukin-25 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-25.
2005-10-21 GO:0045534 negative regulation of interleukin-26 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-26.
2005-10-21 GO:0045535 negative regulation of interleukin-27 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-27.
2005-10-21 GO:0045400 negative regulation of interleukin-3 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-3.
2005-10-21 GO:0045403 negative regulation of interleukin-4 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-4.
2005-10-21 GO:0045406 negative regulation of interleukin-5 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-5.
2005-10-21 GO:0051548 negative regulation of keratinocyte migration Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of keratinocyte migration.
2005-10-21 GO:0035204 negative regulation of lamellocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
2005-10-21 GO:0045710 negative regulation of larval salivary gland boundary specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of salivary gland determination in a larval organism.
2005-10-21 GO:0050949 negative regulation of late stripe melanocyte differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of late stripe melanocyte differentiation.
2005-10-21 GO:0048375 negative regulation of lateral mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of lateral mesoderm cell fate determination.
2005-10-21 GO:0045401 positive regulation of interleukin-3 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-3.
2005-10-21 GO:0045404 positive regulation of interleukin-4 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-4.
2005-10-21 GO:0045407 positive regulation of interleukin-5 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-5.
2005-10-21 GO:0045410 positive regulation of interleukin-6 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-6.
2005-10-21 GO:0045413 positive regulation of interleukin-7 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-7.
2005-10-21 GO:0045416 positive regulation of interleukin-8 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-8.
2005-10-21 GO:0045419 positive regulation of interleukin-9 biosynthetic process Updated DEFINITION Any process that activates or increases the rate, frequency or extent of the formation from simpler components of interleukin-9.
2005-10-21 GO:0030844 positive regulation of intermediate filament depolymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of intermediate filament depolymerization.
2005-10-21 GO:0030841 positive regulation of intermediate filament polymerization Updated DEFINITION Any process that activates or increases the rate, frequency or extent of intermediate filament polymerization.
2005-10-21 GO:0045826 obsolete positive regulation of intermediate filament polymerization and/or depolymerization Updated DEFINITION OBSOLETE. Any process that activates or increases the rate, frequency or extent of intermediate filament polymerization and/or depolymerization.
2005-10-21 GO:0045827 negative regulation of isoprenoid metabolic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the chemical reactions involving isoprenoid.
2005-10-21 GO:0046888 negative regulation of hormone secretion Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the regulated release of a hormone from a cell or group of cells.
2005-10-21 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of an I-kappaB kinase/NF-kappaB induced cascade.
2005-10-21 GO:0045571 negative regulation of imaginal disc growth Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of imaginal disc growth.
2005-10-21 GO:0050777 negative regulation of immune response Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
2005-10-21 GO:0045409 negative regulation of interleukin-6 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-6.
2005-10-21 GO:0045412 negative regulation of interleukin-7 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-7.
2005-10-21 GO:0045415 negative regulation of interleukin-8 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-8.
2005-10-21 GO:0045418 negative regulation of interleukin-9 biosynthetic process Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of interleukin-9.
2005-10-21 GO:0030843 negative regulation of intermediate filament depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate filament depolymerization.
2005-10-21 GO:0030840 negative regulation of intermediate filament polymerization Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate filament polymerization.
2005-10-21 GO:0045825 obsolete negative regulation of intermediate filament polymerization and/or depolymerization Updated DEFINITION OBSOLETE. Any process that stops, prevents or reduces the rate, frequency or extent of intermediate filament polymerization and/or depolymerization.
2005-10-21 GO:0048396 negative regulation of intermediate mesodermal cell fate determination Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate mesoderm cell fate determination.
2005-10-21 GO:0048401 negative regulation of intermediate mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of intermediate mesoderm cell fate specification.
2005-10-21 GO:0043271 negative regulation of ion transport Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the directed movement of charged atoms or small charged molecules into, out of, within or between cells.
2005-10-21 GO:0031586 negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the activity of the IP3 receptor.
2005-10-21 GO:0050943 negative regulation of iridophore differentiation Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of iridophore differentiation.
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