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GO Term History: Displaying 54 audit records for all terms for the date 2005-08-16

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2005-08-16 GO:0051526 NFAT1 protein binding Added DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051527 NFAT2 protein binding Added DEFINITION Interacting selectively with NFAT2 (nuclear factor of activated T cells 2 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051528 NFAT3 protein binding Added DEFINITION Interacting selectively with NFAT3 (nuclear factor of activated T cells 3 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051529 NFAT4 protein binding Added DEFINITION Interacting selectively with NFAT4 (nuclear factor of activated T cells 4 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051530 NFAT5 protein binding Added DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a member of the NFAT transcription factor family which is not calcium regulated.
2005-08-16 GO:0051559 phlobaphene biosynthetic process Added DEFINITION The formation from simpler components of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
2005-08-16 GO:0051558 phlobaphene metabolic process Added DEFINITION The chemical reactions involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
2005-08-16 GO:0051544 positive regulation of elastin biosynthetic process Added DEFINITION Any process that activates or increases the rate of the formation from simpler components of elastin.
2005-08-16 GO:0051549 positive regulation of keratinocyte migration Added DEFINITION Any process that activates or increases the rate of keratinocyte migration.
2005-08-16 GO:0051533 positive regulation of NFAT protein import into nucleus Added DEFINITION Any process that activates or increases the rate of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-08-16 GO:0048661 positive regulation of smooth muscle cell proliferation Added DEFINITION Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
2005-08-16 GO:0051543 regulation of elastin biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the formation from simpler components of elastin.
2005-08-16 GO:0051547 regulation of keratinocyte migration Added DEFINITION Any process that modulates the frequency, rate or extent of keratinocyte migration.
2005-08-16 GO:0051532 regulation of NFAT protein import into nucleus Added DEFINITION Any process that modulates the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-08-16 GO:0048660 regulation of smooth muscle cell proliferation Added DEFINITION Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.
2005-08-16 GO:0031205 endoplasmic reticulum Sec complex Updated DEFINITION A membrane associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2005-08-16 GO:0031206 Sec complex-associated translocon complex Updated DEFINITION A translocon complex physically associated with a Sec complex.
2005-08-16 GO:0031207 Sec62/Sec63 complex Updated DEFINITION A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.
2005-08-16 GO:0048659 smooth muscle cell proliferation Added DEFINITION The multiplication or reproduction of smooth muscle cells, resulting in the rapid expansion of a cell population.
2005-08-16 GO:0051535 syntaxin-5 binding Added DEFINITION Interacting selectively with the SNAP receptor syntaxin-5.
2005-08-16 GO:0031564 transcription antitermination Added DEFINITION Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond a termination site.
2005-08-16 GO:0031565 cytokinesis checkpoint Added DEFINITION A cell cycle checkpoint that ensures the correct temporal ordering of nuclear division and cytokinesis; arrests the cell cycle in G2 upon perturbation of cytokinetic structures. In Schizosaccharomyces, the checkpoint monitors formation and integrity of medial actomyosin ring and septum.
2005-08-16 GO:0031566 actomyosin contractile ring maintenance Added DEFINITION Maintenance of the contractile ring in response to the cytokinesis checkpoint, i.e. when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures.
2005-08-16 GO:0051537 2 iron, 2 sulfur cluster binding Added DEFINITION Interacting selectively with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
2005-08-16 GO:0051538 3 iron, 4 sulfur cluster binding Added DEFINITION Interacting selectively with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.
2005-08-16 GO:0051539 4 iron, 4 sulfur cluster binding Added DEFINITION Interacting selectively with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
2005-08-16 GO:0051551 aurone biosynthetic process Added DEFINITION The formation from simpler components of aurones, a series of yellow plant pigments.
2005-08-16 GO:0051550 aurone metabolic process Added DEFINITION The chemical reactions involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.
2005-08-16 GO:0051545 negative regulation of elastin biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of elastin.
2005-08-16 GO:0051548 negative regulation of keratinocyte migration Added DEFINITION Any process that stops, prevents or reduces the rate of keratinocyte migration.
2005-08-16 GO:0051542 elastin biosynthetic process Added DEFINITION The formation from simpler components of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.
2005-08-16 GO:0051541 elastin metabolic process Added DEFINITION The chemical reactions involving elastin, a glycoprotein which is randomly coiled and cross linked to form elastic fibres that are found in connective tissue.
2005-08-16 GO:0001958 endochondral ossification Added DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2005-08-16 GO:0051553 flavone biosynthetic process Added DEFINITION The formation from simpler components of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
2005-08-16 GO:0051552 flavone metabolic process Added DEFINITION The chemical reactions involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
2005-08-16 GO:0051555 flavonol biosynthetic process Added DEFINITION The formation from simpler components of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
2005-08-16 GO:0051554 flavonol metabolic process Added DEFINITION The chemical reactions involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
2005-08-16 GO:0001957 intramembranous ossification Added DEFINITION The formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2005-08-16 GO:0051536 iron-sulfur cluster binding Added DEFINITION Interacting selectively with an iron-sulfur cluster, a combination of iron and sulfur ions.
2005-08-16 GO:0051546 keratinocyte migration Added DEFINITION The directed movement of keratinocytes, epidermal cells which synthesize keratin, from one site to another.
2005-08-16 GO:0051557 leucoanthocyanidin biosynthetic process Added DEFINITION The formation from simpler components of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
2005-08-16 GO:0051556 leucoanthocyanidin metabolic process Added DEFINITION The chemical reactions involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
2005-08-16 GO:0051540 metal cluster binding Added DEFINITION Interacting selectively with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.
2005-08-16 GO:0051534 negative regulation of NFAT protein import into nucleus Added DEFINITION Any process that modulates the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-08-16 GO:0048662 negative regulation of smooth muscle cell proliferation Added DEFINITION Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
2005-08-16 GO:0048666 neuron development Added DEFINITION The process aimed at the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2005-08-16 GO:0048663 neuron fate commitment Added DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a neuron.
2005-08-16 GO:0048664 neuron fate determination Added DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.
2005-08-16 GO:0048665 neuron fate specification Added DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
2005-08-16 GO:0048667 cell morphogenesis involved in neuron differentiation Added DEFINITION The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
2005-08-16 GO:0045161 neuronal ion channel clustering Updated DEFINITION The process by which voltage-gated sodium and potassium ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
2005-08-16 GO:0051525 NFAT protein binding Added DEFINITION Interacting selectively with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
2005-08-16 GO:0051531 NFAT protein import into nucleus Added DEFINITION The directed movement of NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors, from the cytoplasm into the nucleus. NFAT proteins are dephosphorylated in the cytoplasm by activated calcineurin, which leads to their translocation across the nuclear membrane.
2005-08-16 GO:0001502 cartilage condensation Updated DEFINITION The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2005-08-16 GO:0051526 NFAT1 protein binding Added DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051527 NFAT2 protein binding Added DEFINITION Interacting selectively with NFAT2 (nuclear factor of activated T cells 2 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051528 NFAT3 protein binding Added DEFINITION Interacting selectively with NFAT3 (nuclear factor of activated T cells 3 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051529 NFAT4 protein binding Added DEFINITION Interacting selectively with NFAT4 (nuclear factor of activated T cells 4 protein), a calcium-regulated protein which acts as a transcription factor.
2005-08-16 GO:0051530 NFAT5 protein binding Added DEFINITION Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a member of the NFAT transcription factor family which is not calcium regulated.
2005-08-16 GO:0051559 phlobaphene biosynthetic process Added DEFINITION The formation from simpler components of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
2005-08-16 GO:0051558 phlobaphene metabolic process Added DEFINITION The chemical reactions involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
2005-08-16 GO:0051544 positive regulation of elastin biosynthetic process Added DEFINITION Any process that activates or increases the rate of the formation from simpler components of elastin.
2005-08-16 GO:0051549 positive regulation of keratinocyte migration Added DEFINITION Any process that activates or increases the rate of keratinocyte migration.
2005-08-16 GO:0051533 positive regulation of NFAT protein import into nucleus Added DEFINITION Any process that activates or increases the rate of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-08-16 GO:0048661 positive regulation of smooth muscle cell proliferation Added DEFINITION Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
2005-08-16 GO:0051543 regulation of elastin biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the formation from simpler components of elastin.
2005-08-16 GO:0051547 regulation of keratinocyte migration Added DEFINITION Any process that modulates the frequency, rate or extent of keratinocyte migration.
2005-08-16 GO:0051532 regulation of NFAT protein import into nucleus Added DEFINITION Any process that modulates the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-08-16 GO:0048660 regulation of smooth muscle cell proliferation Added DEFINITION Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.
2005-08-16 GO:0031205 endoplasmic reticulum Sec complex Updated DEFINITION A membrane associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2005-08-16 GO:0031206 Sec complex-associated translocon complex Updated DEFINITION A translocon complex physically associated with a Sec complex.
2005-08-16 GO:0031207 Sec62/Sec63 complex Updated DEFINITION A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.
2005-08-16 GO:0048659 smooth muscle cell proliferation Added DEFINITION The multiplication or reproduction of smooth muscle cells, resulting in the rapid expansion of a cell population.
2005-08-16 GO:0051535 syntaxin-5 binding Added DEFINITION Interacting selectively with the SNAP receptor syntaxin-5.
2005-08-16 GO:0031564 transcription antitermination Added DEFINITION Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond a termination site.
2005-08-16 GO:0031565 cytokinesis checkpoint Added DEFINITION A cell cycle checkpoint that ensures the correct temporal ordering of nuclear division and cytokinesis; arrests the cell cycle in G2 upon perturbation of cytokinetic structures. In Schizosaccharomyces, the checkpoint monitors formation and integrity of medial actomyosin ring and septum.
2005-08-16 GO:0031566 actomyosin contractile ring maintenance Added DEFINITION Maintenance of the contractile ring in response to the cytokinesis checkpoint, i.e. when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures.
2005-08-16 GO:0051537 2 iron, 2 sulfur cluster binding Added DEFINITION Interacting selectively with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
2005-08-16 GO:0051538 3 iron, 4 sulfur cluster binding Added DEFINITION Interacting selectively with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.
2005-08-16 GO:0051539 4 iron, 4 sulfur cluster binding Added DEFINITION Interacting selectively with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
2005-08-16 GO:0051551 aurone biosynthetic process Added DEFINITION The formation from simpler components of aurones, a series of yellow plant pigments.
2005-08-16 GO:0051550 aurone metabolic process Added DEFINITION The chemical reactions involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.
2005-08-16 GO:0051545 negative regulation of elastin biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of elastin.
2005-08-16 GO:0051548 negative regulation of keratinocyte migration Added DEFINITION Any process that stops, prevents or reduces the rate of keratinocyte migration.
2005-08-16 GO:0051542 elastin biosynthetic process Added DEFINITION The formation from simpler components of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.
2005-08-16 GO:0051541 elastin metabolic process Added DEFINITION The chemical reactions involving elastin, a glycoprotein which is randomly coiled and cross linked to form elastic fibres that are found in connective tissue.
2005-08-16 GO:0001958 endochondral ossification Added DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2005-08-16 GO:0051553 flavone biosynthetic process Added DEFINITION The formation from simpler components of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
2005-08-16 GO:0051552 flavone metabolic process Added DEFINITION The chemical reactions involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
2005-08-16 GO:0051555 flavonol biosynthetic process Added DEFINITION The formation from simpler components of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
2005-08-16 GO:0051554 flavonol metabolic process Added DEFINITION The chemical reactions involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
2005-08-16 GO:0001957 intramembranous ossification Added DEFINITION The formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2005-08-16 GO:0051536 iron-sulfur cluster binding Added DEFINITION Interacting selectively with an iron-sulfur cluster, a combination of iron and sulfur ions.
2005-08-16 GO:0051546 keratinocyte migration Added DEFINITION The directed movement of keratinocytes, epidermal cells which synthesize keratin, from one site to another.
2005-08-16 GO:0051557 leucoanthocyanidin biosynthetic process Added DEFINITION The formation from simpler components of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
2005-08-16 GO:0051556 leucoanthocyanidin metabolic process Added DEFINITION The chemical reactions involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
2005-08-16 GO:0051540 metal cluster binding Added DEFINITION Interacting selectively with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.
2005-08-16 GO:0051534 negative regulation of NFAT protein import into nucleus Added DEFINITION Any process that modulates the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
2005-08-16 GO:0048662 negative regulation of smooth muscle cell proliferation Added DEFINITION Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
2005-08-16 GO:0048666 neuron development Added DEFINITION The process aimed at the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2005-08-16 GO:0048663 neuron fate commitment Added DEFINITION The process whereby the developmental fate of a cell becomes restricted such that it will develop into a neuron.
2005-08-16 GO:0048664 neuron fate determination Added DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.
2005-08-16 GO:0048665 neuron fate specification Added DEFINITION The process whereby a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
2005-08-16 GO:0048667 cell morphogenesis involved in neuron differentiation Added DEFINITION The process by which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
2005-08-16 GO:0045161 neuronal ion channel clustering Updated DEFINITION The process by which voltage-gated sodium and potassium ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
2005-08-16 GO:0051525 NFAT protein binding Added DEFINITION Interacting selectively with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
2005-08-16 GO:0051531 NFAT protein import into nucleus Added DEFINITION The directed movement of NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors, from the cytoplasm into the nucleus. NFAT proteins are dephosphorylated in the cytoplasm by activated calcineurin, which leads to their translocation across the nuclear membrane.
2005-08-16 GO:0001502 cartilage condensation Updated DEFINITION The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.
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