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GO Term History: Displaying 100 audit records for all terms for the date 2005-01-11

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2005-01-11 GO:0010229 inflorescence development Added DEFINITION Processes aimed at the progression of an inflorescence over time, from its formation to the mature structure.
2005-01-11 GO:0043231 intracellular membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2005-01-11 GO:0043232 intracellular non-membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
2005-01-11 GO:0005849 mRNA cleavage factor complex Added DEFINITION Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
2005-01-11 GO:0035304 regulation of protein dephosphorylation Added DEFINITION Any process that modulates the frequency, rate or extent of removal of phosphoric groups from a protein.
2005-01-11 GO:0048510 regulation of timing of transition from vegetative to reproductive phase Updated DEFINITION Processes controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.
2005-01-11 GO:0035314 scab formation Added DEFINITION Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.
2005-01-11 GO:0031105 septin complex Added DEFINITION Any of several heterooligomeric complexes containing multiple septins, which may coalesce into the septin ring structure.
2005-01-11 GO:0030481 septin ring (sensu Fungi) Added DEFINITION A ring-shaped structure that forms at the site of cytokinesis in fungal cells; composed of the conserved family of filament forming proteins called septins as well as septin-associated proteins. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2005-01-11 GO:0031107 septin ring disassembly Added DEFINITION The controlled breakdown of a septin ring.
2005-01-11 GO:0031106 septin ring organization Added DEFINITION Control of the formation, spatial distribution, and breakdown of the septin ring.
2005-01-11 GO:0005940 septin ring Added DEFINITION A ring-shaped structure that forms at the site of cytokinesis; composed of the conserved family of filament forming proteins called septins as well as septin-associated proteins.
2005-01-11 GO:0031120 snRNA pseudouridine synthesis Added DEFINITION The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
2005-01-11 GO:0043145 snoRNA 3'-end cleavage Updated DEFINITION The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.
2005-01-11 GO:0031098 stress-activated protein kinase signaling cascade Added DEFINITION A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
2005-01-11 GO:0031119 tRNA pseudouridine synthesis Added DEFINITION The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
2005-01-11 GO:0016439 tRNA-pseudouridine synthase activity Updated DEFINITION Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
2005-01-11 GO:0035316 non-sensory hair organization Added DEFINITION Formation and arrangement of hairs (trichomes), polarized cellular extensions that cover much of the insect epidermis. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).
2005-01-11 GO:0010228 vegetative to reproductive phase transition of meristem Added DEFINITION Processes involved in transforming a meristem producing vegetative structures, such as leaves, into a meristem producing reproductive structures, such as a flower or an inflorescence.
2005-01-11 GO:0035309 wing and notum subfield formation Added DEFINITION Subdivision of the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.
2005-01-11 GO:0035311 wing cell fate specification Added DEFINITION Process by which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.
2005-01-11 GO:0035319 imaginal disc-derived wing hair elongation Added DEFINITION Growth of a prehair in the approximately 10 hour period following its emergence from a wing epidermal cell. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.
2005-01-11 GO:0035317 imaginal disc-derived wing hair organization Added DEFINITION Formation and arrangement of a wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells.
2005-01-11 GO:0035318 imaginal disc-derived wing hair outgrowth Added DEFINITION Extrusion of a cellular projection from the apical membrane of a wing epithelial cell. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.
2005-01-11 GO:0035320 imaginal disc-derived wing hair site selection Added DEFINITION Determination of the site in the cell at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.
2005-01-11 GO:0042060 wound healing Added DEFINITION The series of events that restore integrity to a damaged tissue, following an injury.
2005-01-11 GO:0035313 wound healing, spreading of epidermal cells Added DEFINITION The migration of epithelial cells along or through a wound gap to reestablish a continuous epithelium.
2005-01-11 GO:0005848 mRNA cleavage stimulating factor complex Added DEFINITION A protein complex required for mRNA cleavage but not for poly(A) addition.
2005-01-11 GO:0006379 mRNA cleavage Added DEFINITION Any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
2005-01-11 GO:0001940 male pronucleus Added DEFINITION The pronucleus originating from the spermatozoa that was involved in fertilization.
2005-01-11 GO:0031097 medial cortex Added DEFINITION A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning
2005-01-11 GO:0016020 membrane Updated DEFINITION Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
2005-01-11 GO:0043227 membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2005-01-11 GO:0035312 5'-3' exodeoxyribonuclease activity Added DEFINITION Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.
2005-01-11 GO:0016917 GABA receptor activity Updated DEFINITION Combining with gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to initiate a change in cell activity.
2005-01-11 GO:0050811 GABA receptor binding Updated DEFINITION Interacting selectively with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
2005-01-11 GO:0031093 platelet alpha granule lumen Added DEFINITION The volume enclosed by the membrane of the platelet alpha granule.
2005-01-11 GO:0031092 platelet alpha granule membrane Added DEFINITION The lipid bilayer surrounding the platelet alpha granule.
2005-01-11 GO:0031091 platelet alpha granule Added DEFINITION A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
2005-01-11 GO:0031089 platelet dense granule lumen Added DEFINITION The volume enclosed by the membrane of the platelet dense granule.
2005-01-11 GO:0031088 platelet dense granule membrane Added DEFINITION The lipid bilayer surrounding the platelet dense granule.
2005-01-11 GO:0031096 platelet dense tubular network lumen Added DEFINITION The volume enclosed by the membranes of the platelet dense tubular network.
2005-01-11 GO:0031095 platelet dense tubular network membrane Added DEFINITION The lipid bilayer surrounding the platelet dense tubular network.
2005-01-11 GO:0031094 platelet dense tubular network Added DEFINITION A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.
2005-01-11 GO:0035306 positive regulation of dephosphorylation Added DEFINITION Any process that activates or increases the frequency, rate or extent of removal of phosphoric groups from a molecule.
2005-01-11 GO:0001938 positive regulation of endothelial cell proliferation Added DEFINITION Any process that activates or increases the rate or extent of endothelial cell proliferation.
2005-01-11 GO:0031117 positive regulation of microtubule depolymerization Added DEFINITION Any process that activates or increases the rate of microtubule depolymerization.
2005-01-11 GO:0031112 positive regulation of microtubule polymerization or depolymerization Added DEFINITION Any process that activates or increases the rate of microtubule polymerization or depolymerization.
2005-01-11 GO:0031116 positive regulation of microtubule polymerization Added DEFINITION Any process that activates or increases the rate of microtubule polymerization.
2005-01-11 GO:0045933 positive regulation of muscle contraction Updated DEFINITION Any process that activates or increases the rate of muscle contraction.
2005-01-11 GO:0035307 positive regulation of protein dephosphorylation Added DEFINITION Any process that activates or increases the frequency, rate or extent of removal of phosphoric groups from a protein.
2005-01-11 GO:0009982 pseudouridine synthase activity Added DEFINITION Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
2005-01-11 GO:0001522 pseudouridine synthesis Updated DEFINITION The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs.
2005-01-11 GO:0031118 rRNA pseudouridine synthesis Added DEFINITION The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
2005-01-11 GO:0031099 regeneration Added DEFINITION The regrowth of a lost or destroyed body part, such as an organ or tissue.
2005-01-11 GO:0035303 regulation of dephosphorylation Added DEFINITION Any process that modulates the frequency, rate or extent of removal of phosphoric groups from a molecule.
2005-01-11 GO:0001936 regulation of endothelial cell proliferation Added DEFINITION Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.
2005-01-11 GO:0031114 regulation of microtubule depolymerization Added DEFINITION Any process that modulates the frequency, rate or extent of microtubule depolymerization.
2005-01-11 GO:0031110 regulation of microtubule polymerization or depolymerization Added DEFINITION Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
2005-01-11 GO:0007026 negative regulation of microtubule depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-11 GO:0031111 negative regulation of microtubule polymerization or depolymerization Added DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization or depolymerization.
2005-01-11 GO:0031115 negative regulation of microtubule polymerization Added DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization.
2005-01-11 GO:0035308 negative regulation of protein dephosphorylation Added DEFINITION Any process the stops, prevents or reduces the frequency, rate or extent of removal of phosphoric groups from a protein.
2005-01-11 GO:0031102 neuron projection regeneration Added DEFINITION The regrowth of neuronal processes such as axons or dendrites following their loss or damage.
2005-01-11 GO:0043228 non-membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
2005-01-11 GO:0031109 microtubule polymerization or depolymerization Added DEFINITION Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
2005-01-11 GO:0035305 negative regulation of dephosphorylation Added DEFINITION Any process the stops, prevents or reduces the frequency, rate or extent of removal of phosphoric groups from a molecule.
2005-01-11 GO:0001937 negative regulation of endothelial cell proliferation Added DEFINITION Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
2005-01-11 GO:0035310 notum cell fate specification Added DEFINITION Process by which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.
2005-01-11 GO:0031100 organ regeneration Added DEFINITION The regrowth of a lost or destroyed organ.
2005-01-11 GO:0043233 organelle lumen Updated DEFINITION The volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear membrane lumen.
2005-01-11 GO:0031090 organelle membrane Added DEFINITION The lipid bilayer surrounding an organelle.
2005-01-11 GO:0009780 photosynthetic NADP+ reduction Added DEFINITION Processes by which NADP+ is reduced to NADPH. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions.
2005-01-11 GO:0009781 photosynthetic water oxidation Added DEFINITION Processes by which a molecule of water is oxidised during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
2005-01-11 GO:0046938 phytochelatin biosynthetic process Updated DEFINITION The formation from simpler components of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
2005-01-11 GO:0046937 phytochelatin metabolic process Updated DEFINITION The chemical reactions and physical changes involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
2005-01-11 GO:0031113 regulation of microtubule polymerization Added DEFINITION Any process that modulates the frequency, rate or extent of microtubule polymerization.
2005-01-11 GO:0004890 GABA-A receptor activity Updated DEFINITION Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.
2005-01-11 GO:0004965 G-protein coupled GABA receptor activity Updated DEFINITION Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-B receptors are G-protein coupled receptors.
2005-01-11 GO:0007254 JNK cascade Updated DEFINITION A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
2005-01-11 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity Updated DEFINITION Enables the directed movement of L-gamma-aminobutyric acid (4-aminobutyrate, GABA) into, out of, within or between cells.
2005-01-11 GO:0042491 auditory receptor cell differentiation Updated DEFINITION The processes whereby a relatively unspecialized cell acquires specialized features of an auditory hair cell.
2005-01-11 GO:0031103 axon regeneration Added DEFINITION The regrowth of axons following their loss or damage
2005-01-11 GO:0051278 fungal-type cell wall polysaccharide biosynthetic process Added DEFINITION The formation from simpler components of the polysaccharides which make up the cell wall. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2005-01-11 GO:0043292 contractile fiber Added DEFINITION Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
2005-01-11 GO:0031122 cytoplasmic microtubule organization Added DEFINITION The assembly and arrangement of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
2005-01-11 GO:0031104 dendrite regeneration Added DEFINITION The regrowth of dendrites following their loss or damage
2005-01-11 GO:0001935 endothelial cell proliferation Added DEFINITION The multiplication or reproduction of endothelial cells, resulting in the rapid expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
2005-01-11 GO:0031121 equatorial microtubule organization Added DEFINITION The assembly and arrangement of structures formed of microtubules and associated proteins at the midpoint of a cell.
2005-01-11 GO:0043264 extracellular non-membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.
2005-01-11 GO:0001939 female pronucleus Added DEFINITION The pronucleus originating from the ovum that is being fertilized.
2005-01-11 GO:0031101 fin regeneration Added DEFINITION The regrowth of fin tissue following its loss or destruction.
2005-01-11 GO:0009449 gamma-aminobutyric acid biosynthetic process Updated DEFINITION The formation from simpler components of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
2005-01-11 GO:0009450 gamma-aminobutyric acid catabolic process Updated DEFINITION The breakdown into simpler components of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
2005-01-11 GO:0009448 gamma-aminobutyric acid metabolic process Updated DEFINITION The chemical reactions and physical changes involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
2005-01-11 GO:0007214 gamma-aminobutyric acid signaling pathway Updated DEFINITION The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.
2005-01-11 GO:0015812 gamma-aminobutyric acid transport Updated DEFINITION The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of, within or between cells.
2005-01-11 GO:0035315 hair cell differentiation Added DEFINITION The processes whereby a relatively unspecialized cell acquires specialized features of a hair cell.
2005-01-11 GO:0006398 histone mRNA 3'-end processing Added DEFINITION Any process involved in forming the mature 3' end of a histone mRNA molecule.
2005-01-11 GO:0031108 holo-[acyl-carrier-protein] biosynthetic process Added DEFINITION The formation from simpler components of holo-[acyl-carrier protein].

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2005-01-11 GO:0010229 inflorescence development Added DEFINITION Processes aimed at the progression of an inflorescence over time, from its formation to the mature structure.
2005-01-11 GO:0043231 intracellular membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2005-01-11 GO:0043232 intracellular non-membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
2005-01-11 GO:0005849 mRNA cleavage factor complex Added DEFINITION Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
2005-01-11 GO:0035304 regulation of protein dephosphorylation Added DEFINITION Any process that modulates the frequency, rate or extent of removal of phosphoric groups from a protein.
2005-01-11 GO:0048510 regulation of timing of transition from vegetative to reproductive phase Updated DEFINITION Processes controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.
2005-01-11 GO:0035314 scab formation Added DEFINITION Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.
2005-01-11 GO:0031105 septin complex Added DEFINITION Any of several heterooligomeric complexes containing multiple septins, which may coalesce into the septin ring structure.
2005-01-11 GO:0030481 septin ring (sensu Fungi) Added DEFINITION A ring-shaped structure that forms at the site of cytokinesis in fungal cells; composed of the conserved family of filament forming proteins called septins as well as septin-associated proteins. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2005-01-11 GO:0031107 septin ring disassembly Added DEFINITION The controlled breakdown of a septin ring.
2005-01-11 GO:0031106 septin ring organization Added DEFINITION Control of the formation, spatial distribution, and breakdown of the septin ring.
2005-01-11 GO:0005940 septin ring Added DEFINITION A ring-shaped structure that forms at the site of cytokinesis; composed of the conserved family of filament forming proteins called septins as well as septin-associated proteins.
2005-01-11 GO:0031120 snRNA pseudouridine synthesis Added DEFINITION The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
2005-01-11 GO:0043145 snoRNA 3'-end cleavage Updated DEFINITION The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.
2005-01-11 GO:0031098 stress-activated protein kinase signaling cascade Added DEFINITION A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
2005-01-11 GO:0031119 tRNA pseudouridine synthesis Added DEFINITION The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
2005-01-11 GO:0016439 tRNA-pseudouridine synthase activity Updated DEFINITION Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
2005-01-11 GO:0035316 non-sensory hair organization Added DEFINITION Formation and arrangement of hairs (trichomes), polarized cellular extensions that cover much of the insect epidermis. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).
2005-01-11 GO:0010228 vegetative to reproductive phase transition of meristem Added DEFINITION Processes involved in transforming a meristem producing vegetative structures, such as leaves, into a meristem producing reproductive structures, such as a flower or an inflorescence.
2005-01-11 GO:0035309 wing and notum subfield formation Added DEFINITION Subdivision of the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.
2005-01-11 GO:0035311 wing cell fate specification Added DEFINITION Process by which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.
2005-01-11 GO:0035319 imaginal disc-derived wing hair elongation Added DEFINITION Growth of a prehair in the approximately 10 hour period following its emergence from a wing epidermal cell. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.
2005-01-11 GO:0035317 imaginal disc-derived wing hair organization Added DEFINITION Formation and arrangement of a wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells.
2005-01-11 GO:0035318 imaginal disc-derived wing hair outgrowth Added DEFINITION Extrusion of a cellular projection from the apical membrane of a wing epithelial cell. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.
2005-01-11 GO:0035320 imaginal disc-derived wing hair site selection Added DEFINITION Determination of the site in the cell at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.
2005-01-11 GO:0042060 wound healing Added DEFINITION The series of events that restore integrity to a damaged tissue, following an injury.
2005-01-11 GO:0035313 wound healing, spreading of epidermal cells Added DEFINITION The migration of epithelial cells along or through a wound gap to reestablish a continuous epithelium.
2005-01-11 GO:0005848 mRNA cleavage stimulating factor complex Added DEFINITION A protein complex required for mRNA cleavage but not for poly(A) addition.
2005-01-11 GO:0006379 mRNA cleavage Added DEFINITION Any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
2005-01-11 GO:0001940 male pronucleus Added DEFINITION The pronucleus originating from the spermatozoa that was involved in fertilization.
2005-01-11 GO:0031097 medial cortex Added DEFINITION A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning
2005-01-11 GO:0016020 membrane Updated DEFINITION Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
2005-01-11 GO:0043227 membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2005-01-11 GO:0035312 5'-3' exodeoxyribonuclease activity Added DEFINITION Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.
2005-01-11 GO:0016917 GABA receptor activity Updated DEFINITION Combining with gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to initiate a change in cell activity.
2005-01-11 GO:0050811 GABA receptor binding Updated DEFINITION Interacting selectively with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
2005-01-11 GO:0031093 platelet alpha granule lumen Added DEFINITION The volume enclosed by the membrane of the platelet alpha granule.
2005-01-11 GO:0031092 platelet alpha granule membrane Added DEFINITION The lipid bilayer surrounding the platelet alpha granule.
2005-01-11 GO:0031091 platelet alpha granule Added DEFINITION A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
2005-01-11 GO:0031089 platelet dense granule lumen Added DEFINITION The volume enclosed by the membrane of the platelet dense granule.
2005-01-11 GO:0031088 platelet dense granule membrane Added DEFINITION The lipid bilayer surrounding the platelet dense granule.
2005-01-11 GO:0031096 platelet dense tubular network lumen Added DEFINITION The volume enclosed by the membranes of the platelet dense tubular network.
2005-01-11 GO:0031095 platelet dense tubular network membrane Added DEFINITION The lipid bilayer surrounding the platelet dense tubular network.
2005-01-11 GO:0031094 platelet dense tubular network Added DEFINITION A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.
2005-01-11 GO:0035306 positive regulation of dephosphorylation Added DEFINITION Any process that activates or increases the frequency, rate or extent of removal of phosphoric groups from a molecule.
2005-01-11 GO:0001938 positive regulation of endothelial cell proliferation Added DEFINITION Any process that activates or increases the rate or extent of endothelial cell proliferation.
2005-01-11 GO:0031117 positive regulation of microtubule depolymerization Added DEFINITION Any process that activates or increases the rate of microtubule depolymerization.
2005-01-11 GO:0031112 positive regulation of microtubule polymerization or depolymerization Added DEFINITION Any process that activates or increases the rate of microtubule polymerization or depolymerization.
2005-01-11 GO:0031116 positive regulation of microtubule polymerization Added DEFINITION Any process that activates or increases the rate of microtubule polymerization.
2005-01-11 GO:0045933 positive regulation of muscle contraction Updated DEFINITION Any process that activates or increases the rate of muscle contraction.
2005-01-11 GO:0035307 positive regulation of protein dephosphorylation Added DEFINITION Any process that activates or increases the frequency, rate or extent of removal of phosphoric groups from a protein.
2005-01-11 GO:0009982 pseudouridine synthase activity Added DEFINITION Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
2005-01-11 GO:0001522 pseudouridine synthesis Updated DEFINITION The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs.
2005-01-11 GO:0031118 rRNA pseudouridine synthesis Added DEFINITION The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
2005-01-11 GO:0031099 regeneration Added DEFINITION The regrowth of a lost or destroyed body part, such as an organ or tissue.
2005-01-11 GO:0035303 regulation of dephosphorylation Added DEFINITION Any process that modulates the frequency, rate or extent of removal of phosphoric groups from a molecule.
2005-01-11 GO:0001936 regulation of endothelial cell proliferation Added DEFINITION Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.
2005-01-11 GO:0031114 regulation of microtubule depolymerization Added DEFINITION Any process that modulates the frequency, rate or extent of microtubule depolymerization.
2005-01-11 GO:0031110 regulation of microtubule polymerization or depolymerization Added DEFINITION Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
2005-01-11 GO:0007026 negative regulation of microtubule depolymerization Updated DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
2005-01-11 GO:0031111 negative regulation of microtubule polymerization or depolymerization Added DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization or depolymerization.
2005-01-11 GO:0031115 negative regulation of microtubule polymerization Added DEFINITION Any process that stops, prevents or reduces the rate of microtubule polymerization.
2005-01-11 GO:0035308 negative regulation of protein dephosphorylation Added DEFINITION Any process the stops, prevents or reduces the frequency, rate or extent of removal of phosphoric groups from a protein.
2005-01-11 GO:0031102 neuron projection regeneration Added DEFINITION The regrowth of neuronal processes such as axons or dendrites following their loss or damage.
2005-01-11 GO:0043228 non-membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
2005-01-11 GO:0031109 microtubule polymerization or depolymerization Added DEFINITION Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
2005-01-11 GO:0035305 negative regulation of dephosphorylation Added DEFINITION Any process the stops, prevents or reduces the frequency, rate or extent of removal of phosphoric groups from a molecule.
2005-01-11 GO:0001937 negative regulation of endothelial cell proliferation Added DEFINITION Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
2005-01-11 GO:0035310 notum cell fate specification Added DEFINITION Process by which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.
2005-01-11 GO:0031100 organ regeneration Added DEFINITION The regrowth of a lost or destroyed organ.
2005-01-11 GO:0043233 organelle lumen Updated DEFINITION The volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear membrane lumen.
2005-01-11 GO:0031090 organelle membrane Added DEFINITION The lipid bilayer surrounding an organelle.
2005-01-11 GO:0009780 photosynthetic NADP+ reduction Added DEFINITION Processes by which NADP+ is reduced to NADPH. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions.
2005-01-11 GO:0009781 photosynthetic water oxidation Added DEFINITION Processes by which a molecule of water is oxidised during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
2005-01-11 GO:0046938 phytochelatin biosynthetic process Updated DEFINITION The formation from simpler components of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
2005-01-11 GO:0046937 phytochelatin metabolic process Updated DEFINITION The chemical reactions and physical changes involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
2005-01-11 GO:0031113 regulation of microtubule polymerization Added DEFINITION Any process that modulates the frequency, rate or extent of microtubule polymerization.
2005-01-11 GO:0004890 GABA-A receptor activity Updated DEFINITION Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.
2005-01-11 GO:0004965 G-protein coupled GABA receptor activity Updated DEFINITION Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-B receptors are G-protein coupled receptors.
2005-01-11 GO:0007254 JNK cascade Updated DEFINITION A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
2005-01-11 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity Updated DEFINITION Enables the directed movement of L-gamma-aminobutyric acid (4-aminobutyrate, GABA) into, out of, within or between cells.
2005-01-11 GO:0042491 auditory receptor cell differentiation Updated DEFINITION The processes whereby a relatively unspecialized cell acquires specialized features of an auditory hair cell.
2005-01-11 GO:0031103 axon regeneration Added DEFINITION The regrowth of axons following their loss or damage
2005-01-11 GO:0051278 fungal-type cell wall polysaccharide biosynthetic process Added DEFINITION The formation from simpler components of the polysaccharides which make up the cell wall. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2005-01-11 GO:0043292 contractile fiber Added DEFINITION Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
2005-01-11 GO:0031122 cytoplasmic microtubule organization Added DEFINITION The assembly and arrangement of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
2005-01-11 GO:0031104 dendrite regeneration Added DEFINITION The regrowth of dendrites following their loss or damage
2005-01-11 GO:0001935 endothelial cell proliferation Added DEFINITION The multiplication or reproduction of endothelial cells, resulting in the rapid expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
2005-01-11 GO:0031121 equatorial microtubule organization Added DEFINITION The assembly and arrangement of structures formed of microtubules and associated proteins at the midpoint of a cell.
2005-01-11 GO:0043264 extracellular non-membrane-bounded organelle Updated DEFINITION Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.
2005-01-11 GO:0001939 female pronucleus Added DEFINITION The pronucleus originating from the ovum that is being fertilized.
2005-01-11 GO:0031101 fin regeneration Added DEFINITION The regrowth of fin tissue following its loss or destruction.
2005-01-11 GO:0009449 gamma-aminobutyric acid biosynthetic process Updated DEFINITION The formation from simpler components of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
2005-01-11 GO:0009450 gamma-aminobutyric acid catabolic process Updated DEFINITION The breakdown into simpler components of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
2005-01-11 GO:0009448 gamma-aminobutyric acid metabolic process Updated DEFINITION The chemical reactions and physical changes involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
2005-01-11 GO:0007214 gamma-aminobutyric acid signaling pathway Updated DEFINITION The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.
2005-01-11 GO:0015812 gamma-aminobutyric acid transport Updated DEFINITION The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of, within or between cells.
2005-01-11 GO:0035315 hair cell differentiation Added DEFINITION The processes whereby a relatively unspecialized cell acquires specialized features of a hair cell.
2005-01-11 GO:0006398 histone mRNA 3'-end processing Added DEFINITION Any process involved in forming the mature 3' end of a histone mRNA molecule.
2005-01-11 GO:0031108 holo-[acyl-carrier-protein] biosynthetic process Added DEFINITION The formation from simpler components of holo-[acyl-carrier protein].
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