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GO Term History: Displaying 97 audit records for all terms for the date 2004-12-17

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-12-17 GO:0044250 negative regulation of metabolic activity involved in hibernation Added DEFINITION The slowing of metabolic processes to very low levels in order to conserve energy during hibernation.
2004-12-17 GO:0044252 negative regulation of multicellular organismal metabolic process Added DEFINITION Any process that stops, prevents or reduces the rate of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0045877 negative regulation of smoothened activity Updated DEFINITION Any process that stops, prevents or reduces the activity of the transmembrane protein Smoothened.
2004-12-17 GO:0043109 regulation of smoothened activity Updated TERM regulation of smoothened activity
2004-12-17 GO:0046685 response to arsenic-containing substance Updated TERM response to arsenic
2004-12-17 GO:0031084 BLOC-2 complex Added TERM BLOC-2 complex
2004-12-17 GO:0031085 BLOC-3 complex Added TERM BLOC-3 complex
2004-12-17 GO:0043291 RAVE complex Added TERM RAVE complex
2004-12-17 GO:0008589 regulation of smoothened signaling pathway Updated TERM regulation of smoothened signaling pathway
2004-12-17 GO:0007224 smoothened signaling pathway Updated TERM smoothened signaling pathway
2004-12-17 GO:0007225 patched ligand maturation Updated TERM patched ligand processing
2004-12-17 GO:0007226 regulation of smoothened receptor activity by patched Deleted TERM regulation of smoothened receptor activity by patched
2004-12-17 GO:0031080 nuclear pore outer ring Updated TERM Nup107-160 complex
2004-12-17 GO:0031082 BLOC complex Added TERM BLOC complex
2004-12-17 GO:0031083 BLOC-1 complex Added TERM BLOC-1 complex
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate of smoothened signaling.
2004-12-17 GO:0044271 cellular nitrogen compound biosynthetic process Added DEFINITION The formation from simpler components of organic and inorganic nitrogenous compounds.
2004-12-17 GO:0044270 cellular nitrogen compound catabolic process Added DEFINITION The breakdown into simpler components of organic and inorganic nitrogenous compounds.
2004-12-17 GO:0045878 positive regulation of smoothened activity Updated DEFINITION Any process that activates or increases the activity of the transmembrane protein Smoothened.
2004-12-17 GO:0007228 positive regulation of hh target transcription factor activity Added DEFINITION Upregulation of the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.
2004-12-17 GO:0018754 ammelide aminohydrolase activity Added DEFINITION Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.
2004-12-17 GO:0031082 BLOC complex Added DEFINITION Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.
2004-12-17 GO:0031083 BLOC-1 complex Added DEFINITION A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complx contains the Pallidin, Muted, Cappuccino, Dysbindin, Sapin, BLOS1, BLOS2, AND BLOS3 proteins.
2004-12-17 GO:0031084 BLOC-2 complex Added DEFINITION A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.
2004-12-17 GO:0031085 BLOC-3 complex Added DEFINITION A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.
2004-12-17 GO:0044249 cellular biosynthetic process Added DEFINITION The transformation of simpler substances into more complex ones, carried out by individual cells.
2004-12-17 GO:0044275 cellular carbohydrate catabolic process Added DEFINITION The breakdown into simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
2004-12-17 GO:0044262 cellular carbohydrate metabolic process Added DEFINITION The chemical reactions and physical changes involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
2004-12-17 GO:0045877 negative regulation of smoothened activity Updated TERM negative regulation of smoothened activity
2004-12-17 GO:0045878 positive regulation of smoothened activity Updated TERM positive regulation of smoothened activity
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Updated TERM negative regulation of smoothened signaling pathway
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Updated TERM positive regulation of smoothened signaling pathway
2004-12-17 GO:0044248 cellular catabolic process Added DEFINITION Any metabolic process involving the breakdown of complex substances into smaller products, carried out by individual cells.
2004-12-17 GO:0044242 cellular lipid catabolic process Added DEFINITION The breakdown into simpler components of lipids, as carried out by individual cells.
2004-12-17 GO:0044255 cellular lipid metabolic process Added DEFINITION The chemical reactions and physical changes involving lipids, as carried out by individual cells.
2004-12-17 GO:0044265 cellular macromolecule catabolic process Added DEFINITION The breakdown into simpler components of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
2004-12-17 GO:0044260 cellular macromolecule metabolic process Added DEFINITION The chemical reactions and physical changes involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
2004-12-17 GO:0044237 cellular metabolic process Added DEFINITION Metabolic processes by which individual cells transform chemical substances.
2004-12-17 GO:0044247 cellular polysaccharide catabolic process Added DEFINITION The breakdown into simpler components of polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.
2004-12-17 GO:0044264 cellular polysaccharide metabolic process Added DEFINITION The chemical reactions and physical changes involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.
2004-12-17 GO:0044257 cellular protein catabolic process Added DEFINITION The breakdown into simpler components of a protein by individual cells.
2004-12-17 GO:0044267 cellular protein metabolic process Added DEFINITION The chemical reactions and physical changes involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
2004-12-17 GO:0035302 ecdysteroid 25-hydroxylase activity Added DEFINITION Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.
2004-12-17 GO:0044269 glycerol ether catabolic process Added DEFINITION The breakdown into simpler components of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
2004-12-17 GO:0031078 histone deacetylase activity (H3-K14 specific) Added DEFINITION Catalysis of the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
2004-12-17 GO:0044258 intestinal lipid catabolic process Added DEFINITION The breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.
2004-12-17 GO:0044241 lipid digestion Added DEFINITION The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.
2004-12-17 GO:0031081 nuclear pore distribution Added DEFINITION The orderly synthesis, assembly, regulation, and motion of structures that place nuclear pores in specific positions within the nuclear envelope at a defined time within the cell at large.
2004-12-17 GO:0031080 nuclear pore outer ring Added DEFINITION A subcomplex of the nuclear pore complex (NPC) mRNA export and NPC assembly. Contains conserved nucleoporins and other proteins; for example, the Saccharomyces complex contains Nup84p, Nup85p, Nup120p, Nup145p-C, Seh1p, Sec13p, and Nup133p.
2004-12-17 GO:0044274 multicellular organismal biosynthetic process Added DEFINITION The transformation of simpler substances into more complex ones in multicellular organisms, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044276 multicellular organismal carbohydrate catabolic process Added DEFINITION The breakdown into simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044261 multicellular organismal carbohydrate metabolic process Added DEFINITION The chemical reactions and physical changes involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, in multicellular organisms, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044243 multicellular organismal catabolic process Added DEFINITION Catabolic processes in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
2004-12-17 GO:0044240 multicellular organismal lipid catabolic process Added DEFINITION The breakdown into simpler components of lipids, occurring at the tissue, organ, or organismal level of a multicellular organism.
2004-12-17 GO:0044266 multicellular organismal macromolecule catabolic process Added DEFINITION The breakdown into simpler components of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044259 multicellular organismal macromolecule metabolic process Added DEFINITION The chemical reactions and physical changes involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044236 multicellular organismal metabolic process Added DEFINITION Metabolic processes in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
2004-12-17 GO:0044244 multicellular organismal polysaccharide catabolic process Added DEFINITION The breakdown into simpler components of polysaccharides, occurring at the tissue, organ, or organismal level of a multicellular organism.
2004-12-17 GO:0044263 multicellular organismal polysaccharide metabolic process Added DEFINITION The chemical reactions and physical changes involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, in multicellular organisms that occur at the tissue, organ, or organismal level.
2004-12-17 GO:0044254 multicellular organismal protein catabolic process Added DEFINITION The breakdown into simpler components of a protein in a multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044268 multicellular organismal protein metabolic process Added DEFINITION The chemical reactions and physical changes involving a specific protein, rather than of proteins in general, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0007225 patched ligand maturation Added DEFINITION The post translational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol moieties.
2004-12-17 GO:0031079 picornain 3C activity Added DEFINITION Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
2004-12-17 GO:0044245 polysaccharide digestion Added DEFINITION The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.
2004-12-17 GO:0044253 positive regulation of multicellular organismal metabolic process Added DEFINITION Any process that activates or increases the rate of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Updated DEFINITION Any process that activates or increases the rate of smoothened signaling.
2004-12-17 GO:0044238 primary metabolic process Added DEFINITION Reactions involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
2004-12-17 GO:0044251 protein catabolic process by pepsin Added DEFINITION The breakdown into simpler components of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid).
2004-12-17 GO:0044256 protein digestion Added DEFINITION The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.
2004-12-17 GO:0044246 regulation of multicellular organismal metabolic process Added DEFINITION Any process that modulates the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0043109 regulation of smoothened activity Updated DEFINITION Any process that modulates the activity of the transmembrane protein Smoothened.
2004-12-17 GO:0008589 regulation of smoothened signaling pathway Updated DEFINITION Any process that modulates the frequency, rate or extent of smoothened signaling.
2004-12-17 GO:0046685 response to arsenic-containing substance Updated DEFINITION A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to compounds containing arsenic. These inlcude arsenates, arsenites, and arsenides.
2004-12-17 GO:0044239 salivary polysaccharide catabolic process Added DEFINITION The breakdown into simpler components of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth.
2004-12-17 GO:0007227 signal transduction downstream of smoothened Added DEFINITION The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway.
2004-12-17 GO:0044272 sulfur compound biosynthetic process Added DEFINITION The formation from simpler components of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
2004-12-17 GO:0044273 sulfur compound catabolic process Added DEFINITION The breakdown into simpler components of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
2004-12-17 GO:0007226 regulation of smoothened receptor activity by patched Deleted DEFINITION Modulation of the activity of the smoothened receptor by the patched protein.
2004-12-17 GO:0043291 RAVE complex Added DEFINITION A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme.
2004-12-17 GO:0043109 regulation of smoothened activity Added SECONDARY GO:0007226 (regulation of smoothened receptor activity by patched)
2004-12-17 GO:0018754 ammelide aminohydrolase activity Deleted XREF UM-BBD_enzymeID:e0097
2004-12-17 GO:0007226 regulation of smoothened receptor activity by patched Deleted SYNONYM regulation of smoothened by patched
2004-12-17 GO:0007224 smoothened signaling pathway Deleted SYNONYM smoothened signaling pathway
2004-12-17 GO:0008543 fibroblast growth factor receptor signaling pathway Deleted SYNONYM fibroblast growth factor receptor signaling pathway
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Deleted SYNONYM negative regulation of smoothened receptor signalling pathway
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Deleted SYNONYM positive regulation of smoothened receptor signalling pathway
2004-12-17 GO:0007224 smoothened signaling pathway Added SYNONYM hedgehog signaling pathway
2004-12-17 GO:0007225 patched ligand maturation Added SYNONYM Hedgehog protein processing
2004-12-17 GO:0008543 fibroblast growth factor receptor signaling pathway Added SYNONYM fibroblast growth factor receptor signalling pathway
2004-12-17 GO:0031080 nuclear pore outer ring Added SYNONYM Nup107-120 complex
2004-12-17 GO:0043109 regulation of smoothened activity Added SYNONYM regulation of smoothened by patched
2004-12-17 GO:0043109 regulation of smoothened activity Added SYNONYM regulation of smoothened receptor activity by patched
2004-12-17 GO:0043291 RAVE complex Added SYNONYM regulator of the (H+)-ATPase of the vacuolar and endosomal membranes
2004-12-17 GO:0045877 negative regulation of smoothened activity Added SYNONYM negative regulation of smoothened receptor activity by patched
2004-12-17 GO:0045878 positive regulation of smoothened activity Added SYNONYM positive regulation of smoothened receptor activity by patched
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Added SYNONYM negative regulation of smoothened signalling pathway
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Added SYNONYM positive regulation of smoothened signalling pathway

Terms

Timestamp GO ID GO Term Name Action Category Detail
2004-12-17 GO:0043109 regulation of smoothened activity Updated TERM regulation of smoothened activity
2004-12-17 GO:0046685 response to arsenic-containing substance Updated TERM response to arsenic
2004-12-17 GO:0031084 BLOC-2 complex Added TERM BLOC-2 complex
2004-12-17 GO:0031085 BLOC-3 complex Added TERM BLOC-3 complex
2004-12-17 GO:0043291 RAVE complex Added TERM RAVE complex
2004-12-17 GO:0008589 regulation of smoothened signaling pathway Updated TERM regulation of smoothened signaling pathway
2004-12-17 GO:0007224 smoothened signaling pathway Updated TERM smoothened signaling pathway
2004-12-17 GO:0007225 patched ligand maturation Updated TERM patched ligand processing
2004-12-17 GO:0007226 regulation of smoothened receptor activity by patched Deleted TERM regulation of smoothened receptor activity by patched
2004-12-17 GO:0031080 nuclear pore outer ring Updated TERM Nup107-160 complex
2004-12-17 GO:0031082 BLOC complex Added TERM BLOC complex
2004-12-17 GO:0031083 BLOC-1 complex Added TERM BLOC-1 complex
2004-12-17 GO:0045877 negative regulation of smoothened activity Updated TERM negative regulation of smoothened activity
2004-12-17 GO:0045878 positive regulation of smoothened activity Updated TERM positive regulation of smoothened activity
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Updated TERM negative regulation of smoothened signaling pathway
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Updated TERM positive regulation of smoothened signaling pathway

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-12-17 GO:0044250 negative regulation of metabolic activity involved in hibernation Added DEFINITION The slowing of metabolic processes to very low levels in order to conserve energy during hibernation.
2004-12-17 GO:0044252 negative regulation of multicellular organismal metabolic process Added DEFINITION Any process that stops, prevents or reduces the rate of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0045877 negative regulation of smoothened activity Updated DEFINITION Any process that stops, prevents or reduces the activity of the transmembrane protein Smoothened.
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Updated DEFINITION Any process that stops, prevents or reduces the rate of smoothened signaling.
2004-12-17 GO:0044271 cellular nitrogen compound biosynthetic process Added DEFINITION The formation from simpler components of organic and inorganic nitrogenous compounds.
2004-12-17 GO:0044270 cellular nitrogen compound catabolic process Added DEFINITION The breakdown into simpler components of organic and inorganic nitrogenous compounds.
2004-12-17 GO:0045878 positive regulation of smoothened activity Updated DEFINITION Any process that activates or increases the activity of the transmembrane protein Smoothened.
2004-12-17 GO:0007228 positive regulation of hh target transcription factor activity Added DEFINITION Upregulation of the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.
2004-12-17 GO:0018754 ammelide aminohydrolase activity Added DEFINITION Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.
2004-12-17 GO:0031082 BLOC complex Added DEFINITION Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.
2004-12-17 GO:0031083 BLOC-1 complex Added DEFINITION A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complx contains the Pallidin, Muted, Cappuccino, Dysbindin, Sapin, BLOS1, BLOS2, AND BLOS3 proteins.
2004-12-17 GO:0031084 BLOC-2 complex Added DEFINITION A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.
2004-12-17 GO:0031085 BLOC-3 complex Added DEFINITION A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.
2004-12-17 GO:0044249 cellular biosynthetic process Added DEFINITION The transformation of simpler substances into more complex ones, carried out by individual cells.
2004-12-17 GO:0044275 cellular carbohydrate catabolic process Added DEFINITION The breakdown into simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
2004-12-17 GO:0044262 cellular carbohydrate metabolic process Added DEFINITION The chemical reactions and physical changes involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
2004-12-17 GO:0044248 cellular catabolic process Added DEFINITION Any metabolic process involving the breakdown of complex substances into smaller products, carried out by individual cells.
2004-12-17 GO:0044242 cellular lipid catabolic process Added DEFINITION The breakdown into simpler components of lipids, as carried out by individual cells.
2004-12-17 GO:0044255 cellular lipid metabolic process Added DEFINITION The chemical reactions and physical changes involving lipids, as carried out by individual cells.
2004-12-17 GO:0044265 cellular macromolecule catabolic process Added DEFINITION The breakdown into simpler components of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
2004-12-17 GO:0044260 cellular macromolecule metabolic process Added DEFINITION The chemical reactions and physical changes involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
2004-12-17 GO:0044237 cellular metabolic process Added DEFINITION Metabolic processes by which individual cells transform chemical substances.
2004-12-17 GO:0044247 cellular polysaccharide catabolic process Added DEFINITION The breakdown into simpler components of polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.
2004-12-17 GO:0044264 cellular polysaccharide metabolic process Added DEFINITION The chemical reactions and physical changes involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.
2004-12-17 GO:0044257 cellular protein catabolic process Added DEFINITION The breakdown into simpler components of a protein by individual cells.
2004-12-17 GO:0044267 cellular protein metabolic process Added DEFINITION The chemical reactions and physical changes involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification.
2004-12-17 GO:0035302 ecdysteroid 25-hydroxylase activity Added DEFINITION Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.
2004-12-17 GO:0044269 glycerol ether catabolic process Added DEFINITION The breakdown into simpler components of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
2004-12-17 GO:0031078 histone deacetylase activity (H3-K14 specific) Added DEFINITION Catalysis of the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
2004-12-17 GO:0044258 intestinal lipid catabolic process Added DEFINITION The breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.
2004-12-17 GO:0044241 lipid digestion Added DEFINITION The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.
2004-12-17 GO:0031081 nuclear pore distribution Added DEFINITION The orderly synthesis, assembly, regulation, and motion of structures that place nuclear pores in specific positions within the nuclear envelope at a defined time within the cell at large.
2004-12-17 GO:0031080 nuclear pore outer ring Added DEFINITION A subcomplex of the nuclear pore complex (NPC) mRNA export and NPC assembly. Contains conserved nucleoporins and other proteins; for example, the Saccharomyces complex contains Nup84p, Nup85p, Nup120p, Nup145p-C, Seh1p, Sec13p, and Nup133p.
2004-12-17 GO:0044274 multicellular organismal biosynthetic process Added DEFINITION The transformation of simpler substances into more complex ones in multicellular organisms, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044276 multicellular organismal carbohydrate catabolic process Added DEFINITION The breakdown into simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044261 multicellular organismal carbohydrate metabolic process Added DEFINITION The chemical reactions and physical changes involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, in multicellular organisms, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044243 multicellular organismal catabolic process Added DEFINITION Catabolic processes in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
2004-12-17 GO:0044240 multicellular organismal lipid catabolic process Added DEFINITION The breakdown into simpler components of lipids, occurring at the tissue, organ, or organismal level of a multicellular organism.
2004-12-17 GO:0044266 multicellular organismal macromolecule catabolic process Added DEFINITION The breakdown into simpler components of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044259 multicellular organismal macromolecule metabolic process Added DEFINITION The chemical reactions and physical changes involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044236 multicellular organismal metabolic process Added DEFINITION Metabolic processes in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
2004-12-17 GO:0044244 multicellular organismal polysaccharide catabolic process Added DEFINITION The breakdown into simpler components of polysaccharides, occurring at the tissue, organ, or organismal level of a multicellular organism.
2004-12-17 GO:0044263 multicellular organismal polysaccharide metabolic process Added DEFINITION The chemical reactions and physical changes involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, in multicellular organisms that occur at the tissue, organ, or organismal level.
2004-12-17 GO:0044254 multicellular organismal protein catabolic process Added DEFINITION The breakdown into simpler components of a protein in a multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0044268 multicellular organismal protein metabolic process Added DEFINITION The chemical reactions and physical changes involving a specific protein, rather than of proteins in general, in multicellular organisms occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0007225 patched ligand maturation Added DEFINITION The post translational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol moieties.
2004-12-17 GO:0031079 picornain 3C activity Added DEFINITION Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
2004-12-17 GO:0044245 polysaccharide digestion Added DEFINITION The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.
2004-12-17 GO:0044253 positive regulation of multicellular organismal metabolic process Added DEFINITION Any process that activates or increases the rate of the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Updated DEFINITION Any process that activates or increases the rate of smoothened signaling.
2004-12-17 GO:0044238 primary metabolic process Added DEFINITION Reactions involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
2004-12-17 GO:0044251 protein catabolic process by pepsin Added DEFINITION The breakdown into simpler components of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid).
2004-12-17 GO:0044256 protein digestion Added DEFINITION The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.
2004-12-17 GO:0044246 regulation of multicellular organismal metabolic process Added DEFINITION Any process that modulates the metabolism of a substance in multicellular organism, occurring at the tissue, organ, or organismal level.
2004-12-17 GO:0043109 regulation of smoothened activity Updated DEFINITION Any process that modulates the activity of the transmembrane protein Smoothened.
2004-12-17 GO:0008589 regulation of smoothened signaling pathway Updated DEFINITION Any process that modulates the frequency, rate or extent of smoothened signaling.
2004-12-17 GO:0046685 response to arsenic-containing substance Updated DEFINITION A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to compounds containing arsenic. These inlcude arsenates, arsenites, and arsenides.
2004-12-17 GO:0044239 salivary polysaccharide catabolic process Added DEFINITION The breakdown into simpler components of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth.
2004-12-17 GO:0007227 signal transduction downstream of smoothened Added DEFINITION The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway.
2004-12-17 GO:0044272 sulfur compound biosynthetic process Added DEFINITION The formation from simpler components of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
2004-12-17 GO:0044273 sulfur compound catabolic process Added DEFINITION The breakdown into simpler components of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
2004-12-17 GO:0007226 regulation of smoothened receptor activity by patched Deleted DEFINITION Modulation of the activity of the smoothened receptor by the patched protein.
2004-12-17 GO:0043291 RAVE complex Added DEFINITION A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme.
2004-12-17 GO:0007226 regulation of smoothened receptor activity by patched Deleted SYNONYM regulation of smoothened by patched
2004-12-17 GO:0007224 smoothened signaling pathway Deleted SYNONYM smoothened signaling pathway
2004-12-17 GO:0008543 fibroblast growth factor receptor signaling pathway Deleted SYNONYM fibroblast growth factor receptor signaling pathway
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Deleted SYNONYM negative regulation of smoothened receptor signalling pathway
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Deleted SYNONYM positive regulation of smoothened receptor signalling pathway
2004-12-17 GO:0007224 smoothened signaling pathway Added SYNONYM hedgehog signaling pathway
2004-12-17 GO:0007225 patched ligand maturation Added SYNONYM Hedgehog protein processing
2004-12-17 GO:0008543 fibroblast growth factor receptor signaling pathway Added SYNONYM fibroblast growth factor receptor signalling pathway
2004-12-17 GO:0031080 nuclear pore outer ring Added SYNONYM Nup107-120 complex
2004-12-17 GO:0043109 regulation of smoothened activity Added SYNONYM regulation of smoothened by patched
2004-12-17 GO:0043109 regulation of smoothened activity Added SYNONYM regulation of smoothened receptor activity by patched
2004-12-17 GO:0043291 RAVE complex Added SYNONYM regulator of the (H+)-ATPase of the vacuolar and endosomal membranes
2004-12-17 GO:0045877 negative regulation of smoothened activity Added SYNONYM negative regulation of smoothened receptor activity by patched
2004-12-17 GO:0045878 positive regulation of smoothened activity Added SYNONYM positive regulation of smoothened receptor activity by patched
2004-12-17 GO:0045879 negative regulation of smoothened signaling pathway Added SYNONYM negative regulation of smoothened signalling pathway
2004-12-17 GO:0045880 positive regulation of smoothened signaling pathway Added SYNONYM positive regulation of smoothened signalling pathway

Cross-references

Timestamp GO ID GO Term Name Action Category Detail
2004-12-17 GO:0018754 ammelide aminohydrolase activity Deleted XREF UM-BBD_enzymeID:e0097

Other

Timestamp GO ID GO Term Name Action Category Detail
2004-12-17 GO:0043109 regulation of smoothened activity Added SECONDARY GO:0007226 (regulation of smoothened receptor activity by patched)
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