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GO Term History: Displaying 40 audit records for all terms for the date 2004-08-20

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-08-20 GO:0019934 cGMP-mediated signaling Added DEFINITION A series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
2004-08-20 GO:0019935 cyclic-nucleotide-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response.
2004-08-20 GO:0019239 deaminase activity Added DEFINITION Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3).
2004-08-20 GO:0004153 dihydropterin deaminase activity Added DEFINITION Catalysis of the reaction: 7,8-dihydropterin + H20 = 7,8-dihydrolumazine + NH3.
2004-08-20 GO:0017173 DRAP deaminase activity Added DEFINITION Catalysis of the reaction: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate.
2004-08-20 GO:0001885 endothelial cell development Added DEFINITION The progression of an endothelial cell over time, from its formation to the mature structure.
2004-08-20 GO:0001886 endothelial cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
2004-08-20 GO:0043205 fibril Added DEFINITION Extracellular matrix material consisting of polysaccharides and protein.
2004-08-20 GO:0043206 extracellular fibril organization Added DEFINITION The assembly and arrangement of fibrils, extracellular matrix material consisting of polysaccharides and protein.
2004-08-20 GO:0003933 GTP cyclohydrolase activity Updated DEFINITION Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
2004-08-20 GO:0048017 inositol lipid-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses an inositol lipid to convert an extracellular signal into a response.
2004-08-20 GO:0048016 inositol phosphate-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses a water-soluble inositol phosphate to convert an extracellular signal into a response.
2004-08-20 GO:0004497 monooxygenase activity Updated DEFINITION Catalysis of the incorporation of only one atom of oxygen from dioxygen (O2) into the donor.
2004-08-20 GO:0035021 negative regulation of Rac protein signal transduction Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Rac protein signal transduction.
2004-08-20 GO:0046580 negative regulation of Ras protein signal transduction Updated DEFINITION Any process that stops, prevents or reduces the rate of Ras protein signal transduction.
2004-08-20 GO:0008514 organic anion transmembrane transporter activity Updated DEFINITION Enables the directed movement of organic anions into, out of, within or between cells. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
2004-08-20 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor Updated DEFINITION A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.
2004-08-20 GO:0007234 osmosensory signaling via phosphorelay pathway Updated DEFINITION A series of molecular signals generated in response to osmotic change, as mediated through a two-component (phosphorelay) system.
2004-08-20 GO:0048015 phosphatidylinositol-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses a phosphoinositide to convert an extracellular signal into a response.
2004-08-20 GO:0035022 positive regulation of Rac protein signal transduction Updated DEFINITION Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.
2004-08-20 GO:0046579 positive regulation of Ras protein signal transduction Updated DEFINITION Any process that activates or increases the rate of Ras protein signal transduction.
2004-08-20 GO:0017032 potassium:amino acid symporter activity Updated DEFINITION Catalysis of the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).
2004-08-20 GO:0005956 protein kinase CK2 complex Updated DEFINITION Complex that possesses casein kinase activity, found in nearly every subcellular compartment. Protein kinase CK2 complexes are usually tetramers of two alpha and two beta subunits, and can phosphorylate many protein substrates in addition to casein.
2004-08-20 GO:0016601 Rac protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.
2004-08-20 GO:0007265 Ras protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Ras family of proteins switching to a GTP-bound active state.
2004-08-20 GO:0043193 positive regulation of gene-specific transcription Updated TERM positive regulation of gene-specific transcription
2004-08-20 GO:0043205 fibril Added TERM fibril
2004-08-20 GO:0043206 extracellular fibril organization Added TERM fibril organization and biogenesis
2004-08-20 GO:0019933 cAMP-mediated signaling Added DEFINITION A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
2004-08-20 GO:0019722 calcium-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response.
2004-08-20 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling Updated DEFINITION A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal.
2004-08-20 GO:0000160 phosphorelay signal transduction system Updated DEFINITION A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase that then acts as a phospho-donor to response regulator proteins; also known as histidyl-aspartyl phosphorelay.
2004-08-20 GO:0009031 thiol peroxidase activity Added DEFINITION Catalyses the reaction: reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O.
2004-08-20 GO:0007264 small GTPase mediated signal transduction Added DEFINITION Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
2004-08-20 GO:0019932 second-messenger-mediated signaling Added DEFINITION A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.
2004-08-20 GO:0007266 Rho protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2004-08-20 GO:0046578 regulation of Ras protein signal transduction Updated DEFINITION Any process that modulates the frequency, rate or extent of Ras protein signal transduction.
2004-08-20 GO:0035020 regulation of Rac protein signal transduction Updated DEFINITION Any process that modulates the frequency, rate or extent of Rac protein signal transduction.
2004-08-20 GO:0001885 endothelial cell development Added TERM endothelial cell development
2004-08-20 GO:0001886 endothelial cell morphogenesis Added TERM endothelial cell morphogenesis

Terms

Timestamp GO ID GO Term Name Action Category Detail
2004-08-20 GO:0043193 positive regulation of gene-specific transcription Updated TERM positive regulation of gene-specific transcription
2004-08-20 GO:0043205 fibril Added TERM fibril
2004-08-20 GO:0043206 extracellular fibril organization Added TERM fibril organization and biogenesis
2004-08-20 GO:0001885 endothelial cell development Added TERM endothelial cell development
2004-08-20 GO:0001886 endothelial cell morphogenesis Added TERM endothelial cell morphogenesis

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-08-20 GO:0019934 cGMP-mediated signaling Added DEFINITION A series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
2004-08-20 GO:0019935 cyclic-nucleotide-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response.
2004-08-20 GO:0019239 deaminase activity Added DEFINITION Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3).
2004-08-20 GO:0004153 dihydropterin deaminase activity Added DEFINITION Catalysis of the reaction: 7,8-dihydropterin + H20 = 7,8-dihydrolumazine + NH3.
2004-08-20 GO:0017173 DRAP deaminase activity Added DEFINITION Catalysis of the reaction: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate.
2004-08-20 GO:0001885 endothelial cell development Added DEFINITION The progression of an endothelial cell over time, from its formation to the mature structure.
2004-08-20 GO:0001886 endothelial cell morphogenesis Added DEFINITION The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
2004-08-20 GO:0043205 fibril Added DEFINITION Extracellular matrix material consisting of polysaccharides and protein.
2004-08-20 GO:0043206 extracellular fibril organization Added DEFINITION The assembly and arrangement of fibrils, extracellular matrix material consisting of polysaccharides and protein.
2004-08-20 GO:0003933 GTP cyclohydrolase activity Updated DEFINITION Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
2004-08-20 GO:0048017 inositol lipid-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses an inositol lipid to convert an extracellular signal into a response.
2004-08-20 GO:0048016 inositol phosphate-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses a water-soluble inositol phosphate to convert an extracellular signal into a response.
2004-08-20 GO:0004497 monooxygenase activity Updated DEFINITION Catalysis of the incorporation of only one atom of oxygen from dioxygen (O2) into the donor.
2004-08-20 GO:0035021 negative regulation of Rac protein signal transduction Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of Rac protein signal transduction.
2004-08-20 GO:0046580 negative regulation of Ras protein signal transduction Updated DEFINITION Any process that stops, prevents or reduces the rate of Ras protein signal transduction.
2004-08-20 GO:0008514 organic anion transmembrane transporter activity Updated DEFINITION Enables the directed movement of organic anions into, out of, within or between cells. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
2004-08-20 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor Updated DEFINITION A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.
2004-08-20 GO:0007234 osmosensory signaling via phosphorelay pathway Updated DEFINITION A series of molecular signals generated in response to osmotic change, as mediated through a two-component (phosphorelay) system.
2004-08-20 GO:0048015 phosphatidylinositol-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses a phosphoinositide to convert an extracellular signal into a response.
2004-08-20 GO:0035022 positive regulation of Rac protein signal transduction Updated DEFINITION Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.
2004-08-20 GO:0046579 positive regulation of Ras protein signal transduction Updated DEFINITION Any process that activates or increases the rate of Ras protein signal transduction.
2004-08-20 GO:0017032 potassium:amino acid symporter activity Updated DEFINITION Catalysis of the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).
2004-08-20 GO:0005956 protein kinase CK2 complex Updated DEFINITION Complex that possesses casein kinase activity, found in nearly every subcellular compartment. Protein kinase CK2 complexes are usually tetramers of two alpha and two beta subunits, and can phosphorylate many protein substrates in addition to casein.
2004-08-20 GO:0016601 Rac protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.
2004-08-20 GO:0007265 Ras protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Ras family of proteins switching to a GTP-bound active state.
2004-08-20 GO:0019933 cAMP-mediated signaling Added DEFINITION A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
2004-08-20 GO:0019722 calcium-mediated signaling Updated DEFINITION A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response.
2004-08-20 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling Updated DEFINITION A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal.
2004-08-20 GO:0000160 phosphorelay signal transduction system Updated DEFINITION A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase that then acts as a phospho-donor to response regulator proteins; also known as histidyl-aspartyl phosphorelay.
2004-08-20 GO:0009031 thiol peroxidase activity Added DEFINITION Catalyses the reaction: reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O.
2004-08-20 GO:0007264 small GTPase mediated signal transduction Added DEFINITION Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
2004-08-20 GO:0019932 second-messenger-mediated signaling Added DEFINITION A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.
2004-08-20 GO:0007266 Rho protein signal transduction Updated DEFINITION A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2004-08-20 GO:0046578 regulation of Ras protein signal transduction Updated DEFINITION Any process that modulates the frequency, rate or extent of Ras protein signal transduction.
2004-08-20 GO:0035020 regulation of Rac protein signal transduction Updated DEFINITION Any process that modulates the frequency, rate or extent of Rac protein signal transduction.
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