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GO Term History: Displaying 63 audit records for all terms for the date 2004-08-13

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-08-13 GO:0050901 leukocyte tethering or rolling Updated TERM leukocyte tethering or rolling
2004-08-13 GO:0001884 pyrimidine nucleoside binding Updated TERM pyrimidine nucleoside binding
2004-08-13 GO:0004980 melanocyte-stimulating hormone receptor activity Added SYNONYM MSH receptor activity
2004-08-13 GO:0004980 melanocyte-stimulating hormone receptor activity Added SYNONYM MSHR activity
2004-08-13 GO:0019793 obsolete ISG15 carrier activity Added SYNONYM interferon-stimulated gene-15 carrier activity
2004-08-13 GO:0045249 cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex Updated DEFINITION A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030583 myxococcal fruiting body development Updated DEFINITION Formation of a fruiting body by aggregation of individual cells; a starvation response observed in myxobacteria. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045284 plasma membrane fumarate reductase complex Updated DEFINITION A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (INTERPRO:003510; INTERPRO:00224) and D (INTERPRO:003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045250 cytosolic pyruvate dehydrogenase complex Updated DEFINITION Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045272 plasma membrane respiratory chain complex I Updated DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045274 plasma membrane respiratory chain complex II Updated DEFINITION A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045276 plasma membrane respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045278 plasma membrane respiratory chain complex IV Updated DEFINITION A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030680 dimeric ribonuclease P complex Updated DEFINITION A ribonuclease P complex. Generally contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0005786 signal recognition particle, endoplasmic reticulum targeting Updated DEFINITION A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-08-13 GO:0008608 attachment of spindle microtubules to kinetochore Updated DEFINITION The physical attachment of spindle microtubules to the proteins making up the kinetochore complex.
2004-08-13 GO:0030436 asexual sporulation Updated DEFINITION The formation of spores as in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045282 plasma membrane succinate dehydrogenase complex Updated DEFINITION A multimeric complex which consists of flavoprotein (subunit A ; INTERPRO:003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; INTERPRO:000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045258 plasma membrane succinate dehydrogenase complex (ubiquinone) Updated DEFINITION The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0015619 thiamine pyrophosphate-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O + thiamin pyrophosphate(out) = ADP + phosphate + thiamin pyrophosphate(in).
2004-08-13 GO:0045246 cytosolic tricarboxylic acid cycle enzyme complex Updated DEFINITION Any of the heteromeric enzymes that act in the TCA cycle, as in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045286 plasma membrane ubiquinol-cytochrome-c reductase complex Updated DEFINITION An enzyme complex that contains cytochrome b/b6 and cytochrome c1. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0008328 ionotropic glutamate receptor complex Added DEFINITION A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the centre of the receptor complex.
2004-08-13 GO:0045243 cytosolic isocitrate dehydrogenase complex (NAD+) Updated DEFINITION Complex that possesses isocitrate dehydrogenase (NAD+) activity. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030966 NADH dehydrogenase complex (quinone) (sensu Bacteria) Updated DEFINITION Complex that possesses NADH dehydrogenase (quinone) activity, as in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045280 NADH dehydrogenase complex (ubiquinone) (sensu Bacteria) Updated DEFINITION Complex that possesses NADH dehydrogenase (ubiquinone) activity, as in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045248 cytosolic oxoglutarate dehydrogenase complex Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030542 plasmid partitioning (sensu Bacteria) Updated DEFINITION Any process by which plasmids are segregated or distributed into daughter cells upon cell division. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0000503 proteasome core complex (sensu Bacteria) Updated DEFINITION A multisubunit, barrel shaped protease complex. This complex consists of fourteen subunits of two distinct but related polypeptides. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0000504 obsolete proteasome regulatory particle (sensu Bacteria) Updated DEFINITION A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045260 plasma membrane proton-transporting ATP synthase complex Updated DEFINITION The complex that catalyzes the phosphorylation of ADP to ATP in the plasma membrane, during oxidative phosphorylation; it catalyzes the hydrolysis of ATP to ADP and orthophosphate. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030930 homotetrameric ADPG pyrophosphorylase complex Updated DEFINITION A homotetrameric that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045241 cytosolic alpha-ketoglutarate dehydrogenase complex Updated DEFINITION Complex that possesses alpha-ketoglutarate dehydrogenase activity. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0004135 amylo-alpha-1,6-glucosidase activity Updated DEFINITION Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the 1,6 glycosidic linkages present.
2004-08-13 GO:0042774 plasma membrane ATP synthesis coupled electron transport Updated DEFINITION The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0042777 plasma membrane ATP synthesis coupled proton transport Updated DEFINITION The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030113 capsule (sensu Bacteria) Updated DEFINITION A protective structure surrounding some cells attached externally to the cell wall, often, but not always, constructed of polysaccharides. Capsules play an important role in pathogenicity, preventing phagocytosis by eukaryotic cells. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0043025 neuronal cell body Updated DEFINITION The portion of neuron that includes the nucleus, but excludes all cell processes e.g. axons and dendrites.
2004-08-13 GO:0009274 peptidoglycan-based cell wall Updated DEFINITION A protective structure outside the cytoplasmic membrane composed of peptidoglycan, a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids; also called murein. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009273 peptidoglycan-based cell wall biogenesis Updated DEFINITION The formation, from simpler components, of the cell wall. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0000345 cytosolic DNA-directed RNA polymerase complex Updated DEFINITION The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009282 cytosolic large ribosomal subunit (sensu Bacteria) Updated DEFINITION The large subunit of a ribosome; has a sedimentation coefficient of 50S. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009281 cytosolic ribosome (sensu Bacteria) Updated DEFINITION The cytosolic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009283 cytosolic small ribosomal subunit (sensu Bacteria) Updated DEFINITION The small subunit of a ribosome; has a sedimentation coefficient of 30S. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045247 cytosolic electron transfer flavoprotein complex Updated DEFINITION A protein complex containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009425 bacterial-type flagellum basal body Updated DEFINITION One of the three major substructures of the flagellum; a structure consisting of a rod, a series of rings, the Mot proteins, the switch complex and the flagellum-specific export apparatus. The rings anchor the flagellum to the cytoplasmic membrane (MS ring), the peptidoglycan (P ring) and the outer membrane (L ring). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009433 bacterial-type flagellum basal body, C ring Updated DEFINITION Cytoplasmic ring located at the base of the flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009429 bacterial-type flagellum basal body, proximal rod Updated DEFINITION The portion of the central rod of the flagellar basal body that is proximal to the cell membrane; proximal rod connects the distal rod to the flagellar motor. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030694 bacterial-type flagellum basal body, rod Updated DEFINITION The central portion of the flagellar basal body, which spans the periplasm and threads through the rings. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009420 bacterial-type flagellum filament Updated DEFINITION The long (approximately 20 nm), thin external structure of the flagellum, which acts as a propeller. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009421 bacterial-type flagellum filament cap Updated DEFINITION The proteinaceous structure at the distal tip of the flagellar filament. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009424 bacterial-type flagellum hook Updated DEFINITION The portion of the flagellum that connects the filament to the basal body. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009422 bacterial-type flagellum hook-filament junction Updated DEFINITION The region of the flagellum where the hook and filament meet. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009288 bacterial-type flagellum Updated DEFINITION A 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by the transmembrane proton potential. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009426 bacterial-type flagellum basal body, distal rod Updated DEFINITION The portion of the central rod of the flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009427 bacterial-type flagellum basal body, distal rod, L ring Updated DEFINITION One of the rings of the flagellar basal body; anchors the basal body to the outer membrane. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009428 bacterial-type flagellum basal body, distal rod, P ring Updated DEFINITION One of the rings of the flagellar basal body; anchors the basal body to the peptidoglycan layer. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009431 bacterial-type flagellum basal body, MS ring Updated DEFINITION One of the rings of the flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045262 plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) Updated DEFINITION The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045264 plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) Updated DEFINITION All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045268 plasma membrane proton-transporting ATP synthase, catalytic core Updated DEFINITION The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045270 plasma membrane proton-transporting ATP synthase, central stalk Updated DEFINITION One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045266 plasma membrane proton-transporting ATP synthase, stator stalk Updated DEFINITION One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).

Terms

Timestamp GO ID GO Term Name Action Category Detail
2004-08-13 GO:0050901 leukocyte tethering or rolling Updated TERM leukocyte tethering or rolling
2004-08-13 GO:0001884 pyrimidine nucleoside binding Updated TERM pyrimidine nucleoside binding

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-08-13 GO:0004980 melanocyte-stimulating hormone receptor activity Added SYNONYM MSH receptor activity
2004-08-13 GO:0004980 melanocyte-stimulating hormone receptor activity Added SYNONYM MSHR activity
2004-08-13 GO:0019793 obsolete ISG15 carrier activity Added SYNONYM interferon-stimulated gene-15 carrier activity
2004-08-13 GO:0045249 cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex Updated DEFINITION A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030583 myxococcal fruiting body development Updated DEFINITION Formation of a fruiting body by aggregation of individual cells; a starvation response observed in myxobacteria. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045284 plasma membrane fumarate reductase complex Updated DEFINITION A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (INTERPRO:003510; INTERPRO:00224) and D (INTERPRO:003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045250 cytosolic pyruvate dehydrogenase complex Updated DEFINITION Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045272 plasma membrane respiratory chain complex I Updated DEFINITION A part of the respiratory chain, containing about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron; the iron undergoes oxidation-reduction between Fe(II) and Fe(III). Catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045274 plasma membrane respiratory chain complex II Updated DEFINITION A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045276 plasma membrane respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045278 plasma membrane respiratory chain complex IV Updated DEFINITION A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030680 dimeric ribonuclease P complex Updated DEFINITION A ribonuclease P complex. Generally contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0005786 signal recognition particle, endoplasmic reticulum targeting Updated DEFINITION A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-08-13 GO:0008608 attachment of spindle microtubules to kinetochore Updated DEFINITION The physical attachment of spindle microtubules to the proteins making up the kinetochore complex.
2004-08-13 GO:0030436 asexual sporulation Updated DEFINITION The formation of spores as in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045282 plasma membrane succinate dehydrogenase complex Updated DEFINITION A multimeric complex which consists of flavoprotein (subunit A ; INTERPRO:003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; INTERPRO:000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045258 plasma membrane succinate dehydrogenase complex (ubiquinone) Updated DEFINITION The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0015619 thiamine pyrophosphate-transporting ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O + thiamin pyrophosphate(out) = ADP + phosphate + thiamin pyrophosphate(in).
2004-08-13 GO:0045246 cytosolic tricarboxylic acid cycle enzyme complex Updated DEFINITION Any of the heteromeric enzymes that act in the TCA cycle, as in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045286 plasma membrane ubiquinol-cytochrome-c reductase complex Updated DEFINITION An enzyme complex that contains cytochrome b/b6 and cytochrome c1. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0008328 ionotropic glutamate receptor complex Added DEFINITION A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the centre of the receptor complex.
2004-08-13 GO:0045243 cytosolic isocitrate dehydrogenase complex (NAD+) Updated DEFINITION Complex that possesses isocitrate dehydrogenase (NAD+) activity. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030966 NADH dehydrogenase complex (quinone) (sensu Bacteria) Updated DEFINITION Complex that possesses NADH dehydrogenase (quinone) activity, as in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045280 NADH dehydrogenase complex (ubiquinone) (sensu Bacteria) Updated DEFINITION Complex that possesses NADH dehydrogenase (ubiquinone) activity, as in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045248 cytosolic oxoglutarate dehydrogenase complex Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030542 plasmid partitioning (sensu Bacteria) Updated DEFINITION Any process by which plasmids are segregated or distributed into daughter cells upon cell division. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0000503 proteasome core complex (sensu Bacteria) Updated DEFINITION A multisubunit, barrel shaped protease complex. This complex consists of fourteen subunits of two distinct but related polypeptides. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0000504 obsolete proteasome regulatory particle (sensu Bacteria) Updated DEFINITION A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045260 plasma membrane proton-transporting ATP synthase complex Updated DEFINITION The complex that catalyzes the phosphorylation of ADP to ATP in the plasma membrane, during oxidative phosphorylation; it catalyzes the hydrolysis of ATP to ADP and orthophosphate. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030930 homotetrameric ADPG pyrophosphorylase complex Updated DEFINITION A homotetrameric that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045241 cytosolic alpha-ketoglutarate dehydrogenase complex Updated DEFINITION Complex that possesses alpha-ketoglutarate dehydrogenase activity. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0004135 amylo-alpha-1,6-glucosidase activity Updated DEFINITION Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the 1,6 glycosidic linkages present.
2004-08-13 GO:0042774 plasma membrane ATP synthesis coupled electron transport Updated DEFINITION The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0042777 plasma membrane ATP synthesis coupled proton transport Updated DEFINITION The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030113 capsule (sensu Bacteria) Updated DEFINITION A protective structure surrounding some cells attached externally to the cell wall, often, but not always, constructed of polysaccharides. Capsules play an important role in pathogenicity, preventing phagocytosis by eukaryotic cells. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0043025 neuronal cell body Updated DEFINITION The portion of neuron that includes the nucleus, but excludes all cell processes e.g. axons and dendrites.
2004-08-13 GO:0009274 peptidoglycan-based cell wall Updated DEFINITION A protective structure outside the cytoplasmic membrane composed of peptidoglycan, a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids; also called murein. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009273 peptidoglycan-based cell wall biogenesis Updated DEFINITION The formation, from simpler components, of the cell wall. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0000345 cytosolic DNA-directed RNA polymerase complex Updated DEFINITION The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009282 cytosolic large ribosomal subunit (sensu Bacteria) Updated DEFINITION The large subunit of a ribosome; has a sedimentation coefficient of 50S. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009281 cytosolic ribosome (sensu Bacteria) Updated DEFINITION The cytosolic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009283 cytosolic small ribosomal subunit (sensu Bacteria) Updated DEFINITION The small subunit of a ribosome; has a sedimentation coefficient of 30S. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045247 cytosolic electron transfer flavoprotein complex Updated DEFINITION A protein complex containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009425 bacterial-type flagellum basal body Updated DEFINITION One of the three major substructures of the flagellum; a structure consisting of a rod, a series of rings, the Mot proteins, the switch complex and the flagellum-specific export apparatus. The rings anchor the flagellum to the cytoplasmic membrane (MS ring), the peptidoglycan (P ring) and the outer membrane (L ring). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009433 bacterial-type flagellum basal body, C ring Updated DEFINITION Cytoplasmic ring located at the base of the flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009429 bacterial-type flagellum basal body, proximal rod Updated DEFINITION The portion of the central rod of the flagellar basal body that is proximal to the cell membrane; proximal rod connects the distal rod to the flagellar motor. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0030694 bacterial-type flagellum basal body, rod Updated DEFINITION The central portion of the flagellar basal body, which spans the periplasm and threads through the rings. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009420 bacterial-type flagellum filament Updated DEFINITION The long (approximately 20 nm), thin external structure of the flagellum, which acts as a propeller. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009421 bacterial-type flagellum filament cap Updated DEFINITION The proteinaceous structure at the distal tip of the flagellar filament. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009424 bacterial-type flagellum hook Updated DEFINITION The portion of the flagellum that connects the filament to the basal body. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009422 bacterial-type flagellum hook-filament junction Updated DEFINITION The region of the flagellum where the hook and filament meet. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009288 bacterial-type flagellum Updated DEFINITION A 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by the transmembrane proton potential. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009426 bacterial-type flagellum basal body, distal rod Updated DEFINITION The portion of the central rod of the flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009427 bacterial-type flagellum basal body, distal rod, L ring Updated DEFINITION One of the rings of the flagellar basal body; anchors the basal body to the outer membrane. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009428 bacterial-type flagellum basal body, distal rod, P ring Updated DEFINITION One of the rings of the flagellar basal body; anchors the basal body to the peptidoglycan layer. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0009431 bacterial-type flagellum basal body, MS ring Updated DEFINITION One of the rings of the flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045262 plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) Updated DEFINITION The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045264 plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) Updated DEFINITION All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045268 plasma membrane proton-transporting ATP synthase, catalytic core Updated DEFINITION The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045270 plasma membrane proton-transporting ATP synthase, central stalk Updated DEFINITION One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
2004-08-13 GO:0045266 plasma membrane proton-transporting ATP synthase, stator stalk Updated DEFINITION One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. As in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2).
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