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GO Term History: Displaying 97 audit records for all terms for the date 2004-04-17

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-04-17 GO:0001859 complement component C3dg receptor activity Added DEFINITION Combining with the C3dg product of the complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001855 complement component C4b binding Added DEFINITION Interacting selectively with the C4b product of the classical complement cascade.
2004-04-17 GO:0001861 complement component C4b receptor activity Added DEFINITION Combining with the C4b product of the classical complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001856 complement component C5a binding Added DEFINITION Interacting selectively with the C5a product of the complement cascade.
2004-04-17 GO:0001852 complement component iC3b binding Added DEFINITION Interacting selectively with the iC3b product of the complement cascade.
2004-04-17 GO:0001858 complement component iC3b receptor activity Added DEFINITION Combining with the iC3b product of the complement cascade to initiate a change in cell activity.
2004-04-17 GO:0004693 cyclin-dependent protein serine/threonine kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, where activity is dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2004-04-17 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity Updated DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins.
2004-04-17 GO:0000076 DNA replication checkpoint Updated DEFINITION A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
2004-04-17 GO:0043135 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity Added DEFINITION Catalysis of the hydrolysis of the diphosphate bond in 5-phosphoribosyl 1-pyrophosphate.
2004-04-17 GO:0030929 ADPG pyrophosphorylase complex Added DEFINITION Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits.
2004-04-17 GO:0030930 homotetrameric ADPG pyrophosphorylase complex Added DEFINITION A homotetrameric that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the eubacteria (Bacteria, ncbi_taxonomy_id:2).
2004-04-17 GO:0030931 heterotetrameric ADPG pyrophosphorylase complex Added DEFINITION A heterotetrameric that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-04-17 GO:0030932 amyloplast ADPG pyrophosphorylase complex Added DEFINITION An ADPG pyrophosphorylase complex found in the amyloplast.
2004-04-17 GO:0015922 aspartate oxidase activity Added DEFINITION Catalysis of the reaction: aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.
2004-04-17 GO:0048321 axial mesodermal cell differentiation Added DEFINITION Development of the axial mesoderm cell type. This will involve the change of a cell or set of cells from one cell identity to another.
2004-04-17 GO:0048322 axial mesodermal cell fate commitment Added DEFINITION The process by which a cell becomes committed to become an axial mesoderm cell.
2004-04-17 GO:0048323 axial mesodermal cell fate determination Added DEFINITION Process involved in axial mesoderm cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate into a axial mesoderm cell.
2004-04-17 GO:0048327 axial mesodermal cell fate specification Added DEFINITION The processes involved in the specification of axial mesoderm identity.
2004-04-17 GO:0048318 axial mesoderm development Added DEFINITION Biological processes specifically aimed at the progression of the axial mesoderm over time, from its initial formation to a mature structure.
2004-04-17 GO:0048320 axial mesoderm formation Added DEFINITION Biological processes that contribute to the act of giving rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
2004-04-17 GO:0048319 axial mesoderm morphogenesis Added DEFINITION Developmental processes by which the axial mesoderm is generated and organized. Morphogenesis pertains to the creation of form.
2004-04-17 GO:0048331 axial mesoderm structural organization Added DEFINITION Biological processes that contribute to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
2004-04-17 GO:0005621 cellular bud scar Updated DEFINITION Crater-like ring of chitinous scar tissue located on the surface of the mother cell, as seen in budding fungi. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.
2004-04-17 GO:0030933 chloroplast ADPG pyrophosphorylase complex Added DEFINITION An ADPG pyrophosphorylase complex found in the chloroplast.
2004-04-17 GO:0001862 collectin binding Added DEFINITION Interacting selectively with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.
2004-04-17 GO:0001863 collectin receptor activity Added DEFINITION Combining with a collectin to initiate a change in cell activity.
2004-04-17 GO:0001848 complement binding Added DEFINITION Interacting selectively with any component or product of the complement cascade.
2004-04-17 GO:0001849 complement component C1q binding Added DEFINITION Interacting selectively with the C1q component of the classical complement cascade.
2004-04-17 GO:0001857 complement component C1q receptor activity Added DEFINITION Combining with the C1q component of the classical complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001850 complement component C3a binding Added DEFINITION Interacting selectively with the C3a product of the complement cascade.
2004-04-17 GO:0001851 complement component C3b binding Added DEFINITION Interacting selectively with the C3b product of the complement cascade.
2004-04-17 GO:0001854 complement component C3d binding Added DEFINITION Interacting selectively with the C3d product of the complement cascade.
2004-04-17 GO:0043136 glycerol-3-phosphatase activity Added DEFINITION Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
2004-04-17 GO:0007506 gonadal mesoderm development Updated DEFINITION The formation and subsequent development of the gonadal mesoderm, the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.
2004-04-17 GO:0051020 GTPase binding Added DEFINITION Interacting selectively with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
2004-04-17 GO:0004709 MAP kinase kinase kinase activity Updated DEFINITION Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
2004-04-17 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, where activity is dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2004-04-17 GO:0048336 positive regulation of mesodermal cell fate determination Added DEFINITION Any process that activates or increases the rate of mesoderm cell fate determination.
2004-04-17 GO:0048337 positive regulation of mesodermal cell fate specification Added DEFINITION Any process that activates or increases the rate of mesoderm cell fate specification.
2004-04-17 GO:0048346 positive regulation of paraxial mesodermal cell fate determination Added DEFINITION Any process that activates or increases the rate of paraxial mesoderm cell fate determination.
2004-04-17 GO:0048350 positive regulation of paraxial mesodermal cell fate specification Added DEFINITION Any process that activates or increases the rate of paraxial mesoderm cell fate specification.
2004-04-17 GO:0008538 proteasome activator activity Updated DEFINITION Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.
2004-04-17 GO:0051018 protein kinase A binding Added DEFINITION Interacting selectively with protein kinase A.
2004-04-17 GO:0008536 Ran GTPase binding Updated DEFINITION Interacting selectively with RAN, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
2004-04-17 GO:0048324 regulation of axial mesodermal cell fate determination Added DEFINITION Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.
2004-04-17 GO:0048328 regulation of axial mesodermal cell fate specification Added DEFINITION Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.
2004-04-17 GO:0051023 regulation of immunoglobulin secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins from a cell or group of cells.
2004-04-17 GO:0048334 regulation of mesodermal cell fate determination Added DEFINITION Any process that modulates the frequency\\, rate or extent of mesoderm cell fate determination.
2004-04-17 GO:0042661 regulation of mesodermal cell fate specification Updated DEFINITION Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.
2004-04-17 GO:0048345 regulation of paraxial mesodermal cell fate determination Added DEFINITION Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.
2004-04-17 GO:0048349 regulation of paraxial mesodermal cell fate specification Added DEFINITION Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.
2004-04-17 GO:0051022 Rho GDP-dissociation inhibitor binding Added DEFINITION Interacting selectively with a Rho GDP-dissociation inhibitor protein.
2004-04-17 GO:0019948 SUMO activating enzyme activity Updated DEFINITION Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier, SUMO, through the formation of an ATP-dependent high-energy thioester bond.
2004-04-17 GO:0019789 SUMO transferase activity Updated DEFINITION Catalysis of ATP-dependent isopeptide bond formation between the carboxy terminal glycine residues of the small ubiquitin-related modifier, SUMO, and a substrate lysine residue, leading to the formation of predominately monosumoylated proteins with modified function.
2004-04-17 GO:0016929 SUMO-specific protease activity Updated DEFINITION Catalysis of the hydrolysis of SUMO, a small ubiquitin-related modifier, from previously sumoylated substrates.
2004-04-17 GO:0000812 Swr1 complex Added DEFINITION A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
2004-04-17 GO:0016233 telomere capping Updated DEFINITION A process in which specific single-stranded telomeric DNA binding proteins interact with the ends of linear chromosomes, ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA.
2004-04-17 GO:0008640 ubiquitin-like conjugating enzyme activity Updated DEFINITION Catalysis of the covalent attachment of ubiquitin-like proteins to lysine residues on the target protein. This function may be performed alone or in conjunction with an E3, ubiquitin-like protein ligase.
2004-04-17 GO:0048333 mesodermal cell differentiation Added DEFINITION Development of the mesoderm cell type. This will involve the change of a cell or set of cells from one cell identity to another.
2004-04-17 GO:0007498 mesoderm development Updated DEFINITION Biological processes specifically aimed at the progression of the mesoderm over time, from its initial formation to a mature structure. Mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
2004-04-17 GO:0048332 mesoderm morphogenesis Added DEFINITION Developmental processes by which the mesoderm is generated and organized. Morphogenesis pertains to the creation of form.
2004-04-17 GO:0048338 mesoderm structural organization Added DEFINITION Biological processes that contribute to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.
2004-04-17 GO:0051019 mitogen-activated protein kinase binding Added DEFINITION Interacting selectively with a mitogen-activated protein kinase.
2004-04-17 GO:0007093 mitotic cell cycle checkpoint Updated DEFINITION A signal transduction based surveillance mechanism that ensures accurate chromosome segregation by preventing premature passage through and exit from mitosis. Events that are monitored include the formation of a correctly assembled spindle, the position of the spindle pole (centrosome) and the orientation of the spindle.
2004-04-17 GO:0007064 mitotic sister chromatid cohesion Updated DEFINITION The physical attachment between sister chromatids that is established during S phase of the mitotic cycle at discrete sites along the entire chromosome, maintained until the metaphase-anaphase transition, and dissolved when sisters separate to opposite poles. This cohesion cycle is critical for high fidelity chromosome transmission.
2004-04-17 GO:0043132 NAD transport Added DEFINITION The directed movement of NAD (nicotinamide adenine dinucleotide) into, out of, within or between cells.
2004-04-17 GO:0048325 negative regulation of axial mesodermal cell fate determination Added DEFINITION Any process that stops, prevents or reduces the rate of axial mesoderm cell fate determination.
2004-04-17 GO:0048329 negative regulation of axial mesodermal cell fate specification Added DEFINITION Any process that stops, prevents or reduces the rate of axial mesoderm cell fate specification.
2004-04-17 GO:0051025 negative regulation of immunoglobulin secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of immunoglobulins from a cell or group of cells.
2004-04-17 GO:0048335 negative regulation of mesodermal cell fate determination Added DEFINITION Any process that stops, prevents or reduces the rate of mesoderm cell fate determination.
2004-04-17 GO:0042662 negative regulation of mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate of mesoderm cell fate specification.
2004-04-17 GO:0048347 negative regulation of paraxial mesodermal cell fate determination Added DEFINITION Any process that stops, prevents or reduces the rate of paraxial mesoderm cell fate determination.
2004-04-17 GO:0048351 negative regulation of paraxial mesodermal cell fate specification Added DEFINITION Any process that stops, prevents or reduces the rate of paraxial mesoderm cell fate specification.
2004-04-17 GO:0015664 nicotinamide mononucleotide permease activity Updated DEFINITION Catalysis of the transport of nicotinic acid across biological membranes.
2004-04-17 GO:0001846 opsonin binding Added DEFINITION Interacting selectively with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material.
2004-04-17 GO:0001847 opsonin receptor activity Added DEFINITION Combining with an opsonin to initiate a change in cell activity.
2004-04-17 GO:0030916 otic vesicle formation Updated DEFINITION The developmental processes resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.
2004-04-17 GO:0048342 paraxial mesodermal cell differentiation Added DEFINITION Development of the paraxial mesoderm cell type. This will involve the change of a cell or set of cells from one cell identity to another.
2004-04-17 GO:0048343 paraxial mesodermal cell fate commitment Added DEFINITION The process by which a cell becomes committed to become a paraxial mesoderm cell.
2004-04-17 GO:0048344 paraxial mesodermal cell fate determination Added DEFINITION Process involved in paraxial mesoderm cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate into a paraxial mesoderm cell.
2004-04-17 GO:0048348 paraxial mesodermal cell fate specification Added DEFINITION The processes involved in the specification of mesoderm cell identity.
2004-04-17 GO:0048339 paraxial mesoderm development Added DEFINITION Biological processes specifically aimed at the progression of the paraxial mesoderm over time, from its initial formation to a mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.
2004-04-17 GO:0048341 paraxial mesoderm formation Added DEFINITION Biological processes that contribute to the act of giving rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
2004-04-17 GO:0048340 paraxial mesoderm morphogenesis Added DEFINITION Developmental processes by which the paraxial mesoderm is generated and organized. Morphogenesis pertains to the creation of form.
2004-04-17 GO:0048352 paraxial mesoderm structural organization Added DEFINITION Biological processes that contribute to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
2004-04-17 GO:0001864 pentraxin binding Added DEFINITION Interacting selectively with a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.
2004-04-17 GO:0001845 phagolysosome assembly Added DEFINITION The processes involved with the intracellular changes to phagosomes, the vesicles formed by phagocytosis, which include fusion to lysosomes in most cell types.
2004-04-17 GO:0048326 positive regulation of axial mesodermal cell fate determination Added DEFINITION Any process that activates or increases the rate of axial mesoderm cell fate determination.
2004-04-17 GO:0048330 positive regulation of axial mesodermal cell fate specification Added DEFINITION Any process that activates or increases the rate of.
2004-04-17 GO:0051024 positive regulation of immunoglobulin secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of immunoglobulins from a cell or group of cells.
2004-04-17 GO:0043137 DNA replication, removal of RNA primer Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2004-04-17 GO:0030928 dopachrome decarboxylase activity Added DEFINITION Catalysis of the decarboxylation of L-dopachrome to form 5,6-dihydroxyindole.
2004-04-17 GO:0005769 early endosome Updated DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2004-04-17 GO:0051021 GDP-dissociation inhibitor binding Added DEFINITION Interacting selectively with a GDP-dissociation inhibitor protein.
2004-04-17 GO:0001860 complement component C3d receptor activity Added DEFINITION Combining with the C3d product of the complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001853 complement component C3dg binding Added DEFINITION Interacting selectively with the C3dg product of the complement cascade.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-04-17 GO:0001859 complement component C3dg receptor activity Added DEFINITION Combining with the C3dg product of the complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001855 complement component C4b binding Added DEFINITION Interacting selectively with the C4b product of the classical complement cascade.
2004-04-17 GO:0001861 complement component C4b receptor activity Added DEFINITION Combining with the C4b product of the classical complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001856 complement component C5a binding Added DEFINITION Interacting selectively with the C5a product of the complement cascade.
2004-04-17 GO:0001852 complement component iC3b binding Added DEFINITION Interacting selectively with the iC3b product of the complement cascade.
2004-04-17 GO:0001858 complement component iC3b receptor activity Added DEFINITION Combining with the iC3b product of the complement cascade to initiate a change in cell activity.
2004-04-17 GO:0004693 cyclin-dependent protein serine/threonine kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, where activity is dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2004-04-17 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity Updated DEFINITION Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins.
2004-04-17 GO:0000076 DNA replication checkpoint Updated DEFINITION A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
2004-04-17 GO:0043135 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity Added DEFINITION Catalysis of the hydrolysis of the diphosphate bond in 5-phosphoribosyl 1-pyrophosphate.
2004-04-17 GO:0030929 ADPG pyrophosphorylase complex Added DEFINITION Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits.
2004-04-17 GO:0030930 homotetrameric ADPG pyrophosphorylase complex Added DEFINITION A homotetrameric that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the eubacteria (Bacteria, ncbi_taxonomy_id:2).
2004-04-17 GO:0030931 heterotetrameric ADPG pyrophosphorylase complex Added DEFINITION A heterotetrameric that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-04-17 GO:0030932 amyloplast ADPG pyrophosphorylase complex Added DEFINITION An ADPG pyrophosphorylase complex found in the amyloplast.
2004-04-17 GO:0015922 aspartate oxidase activity Added DEFINITION Catalysis of the reaction: aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.
2004-04-17 GO:0048321 axial mesodermal cell differentiation Added DEFINITION Development of the axial mesoderm cell type. This will involve the change of a cell or set of cells from one cell identity to another.
2004-04-17 GO:0048322 axial mesodermal cell fate commitment Added DEFINITION The process by which a cell becomes committed to become an axial mesoderm cell.
2004-04-17 GO:0048323 axial mesodermal cell fate determination Added DEFINITION Process involved in axial mesoderm cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate into a axial mesoderm cell.
2004-04-17 GO:0048327 axial mesodermal cell fate specification Added DEFINITION The processes involved in the specification of axial mesoderm identity.
2004-04-17 GO:0048318 axial mesoderm development Added DEFINITION Biological processes specifically aimed at the progression of the axial mesoderm over time, from its initial formation to a mature structure.
2004-04-17 GO:0048320 axial mesoderm formation Added DEFINITION Biological processes that contribute to the act of giving rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
2004-04-17 GO:0048319 axial mesoderm morphogenesis Added DEFINITION Developmental processes by which the axial mesoderm is generated and organized. Morphogenesis pertains to the creation of form.
2004-04-17 GO:0048331 axial mesoderm structural organization Added DEFINITION Biological processes that contribute to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
2004-04-17 GO:0005621 cellular bud scar Updated DEFINITION Crater-like ring of chitinous scar tissue located on the surface of the mother cell, as seen in budding fungi. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.
2004-04-17 GO:0030933 chloroplast ADPG pyrophosphorylase complex Added DEFINITION An ADPG pyrophosphorylase complex found in the chloroplast.
2004-04-17 GO:0001862 collectin binding Added DEFINITION Interacting selectively with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.
2004-04-17 GO:0001863 collectin receptor activity Added DEFINITION Combining with a collectin to initiate a change in cell activity.
2004-04-17 GO:0001848 complement binding Added DEFINITION Interacting selectively with any component or product of the complement cascade.
2004-04-17 GO:0001849 complement component C1q binding Added DEFINITION Interacting selectively with the C1q component of the classical complement cascade.
2004-04-17 GO:0001857 complement component C1q receptor activity Added DEFINITION Combining with the C1q component of the classical complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001850 complement component C3a binding Added DEFINITION Interacting selectively with the C3a product of the complement cascade.
2004-04-17 GO:0001851 complement component C3b binding Added DEFINITION Interacting selectively with the C3b product of the complement cascade.
2004-04-17 GO:0001854 complement component C3d binding Added DEFINITION Interacting selectively with the C3d product of the complement cascade.
2004-04-17 GO:0043136 glycerol-3-phosphatase activity Added DEFINITION Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
2004-04-17 GO:0007506 gonadal mesoderm development Updated DEFINITION The formation and subsequent development of the gonadal mesoderm, the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.
2004-04-17 GO:0051020 GTPase binding Added DEFINITION Interacting selectively with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
2004-04-17 GO:0004709 MAP kinase kinase kinase activity Updated DEFINITION Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
2004-04-17 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, where activity is dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
2004-04-17 GO:0048336 positive regulation of mesodermal cell fate determination Added DEFINITION Any process that activates or increases the rate of mesoderm cell fate determination.
2004-04-17 GO:0048337 positive regulation of mesodermal cell fate specification Added DEFINITION Any process that activates or increases the rate of mesoderm cell fate specification.
2004-04-17 GO:0048346 positive regulation of paraxial mesodermal cell fate determination Added DEFINITION Any process that activates or increases the rate of paraxial mesoderm cell fate determination.
2004-04-17 GO:0048350 positive regulation of paraxial mesodermal cell fate specification Added DEFINITION Any process that activates or increases the rate of paraxial mesoderm cell fate specification.
2004-04-17 GO:0008538 proteasome activator activity Updated DEFINITION Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.
2004-04-17 GO:0051018 protein kinase A binding Added DEFINITION Interacting selectively with protein kinase A.
2004-04-17 GO:0008536 Ran GTPase binding Updated DEFINITION Interacting selectively with RAN, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
2004-04-17 GO:0048324 regulation of axial mesodermal cell fate determination Added DEFINITION Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.
2004-04-17 GO:0048328 regulation of axial mesodermal cell fate specification Added DEFINITION Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.
2004-04-17 GO:0051023 regulation of immunoglobulin secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins from a cell or group of cells.
2004-04-17 GO:0048334 regulation of mesodermal cell fate determination Added DEFINITION Any process that modulates the frequency\\, rate or extent of mesoderm cell fate determination.
2004-04-17 GO:0042661 regulation of mesodermal cell fate specification Updated DEFINITION Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.
2004-04-17 GO:0048345 regulation of paraxial mesodermal cell fate determination Added DEFINITION Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.
2004-04-17 GO:0048349 regulation of paraxial mesodermal cell fate specification Added DEFINITION Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.
2004-04-17 GO:0051022 Rho GDP-dissociation inhibitor binding Added DEFINITION Interacting selectively with a Rho GDP-dissociation inhibitor protein.
2004-04-17 GO:0019948 SUMO activating enzyme activity Updated DEFINITION Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier, SUMO, through the formation of an ATP-dependent high-energy thioester bond.
2004-04-17 GO:0019789 SUMO transferase activity Updated DEFINITION Catalysis of ATP-dependent isopeptide bond formation between the carboxy terminal glycine residues of the small ubiquitin-related modifier, SUMO, and a substrate lysine residue, leading to the formation of predominately monosumoylated proteins with modified function.
2004-04-17 GO:0016929 SUMO-specific protease activity Updated DEFINITION Catalysis of the hydrolysis of SUMO, a small ubiquitin-related modifier, from previously sumoylated substrates.
2004-04-17 GO:0000812 Swr1 complex Added DEFINITION A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
2004-04-17 GO:0016233 telomere capping Updated DEFINITION A process in which specific single-stranded telomeric DNA binding proteins interact with the ends of linear chromosomes, ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA.
2004-04-17 GO:0008640 ubiquitin-like conjugating enzyme activity Updated DEFINITION Catalysis of the covalent attachment of ubiquitin-like proteins to lysine residues on the target protein. This function may be performed alone or in conjunction with an E3, ubiquitin-like protein ligase.
2004-04-17 GO:0048333 mesodermal cell differentiation Added DEFINITION Development of the mesoderm cell type. This will involve the change of a cell or set of cells from one cell identity to another.
2004-04-17 GO:0007498 mesoderm development Updated DEFINITION Biological processes specifically aimed at the progression of the mesoderm over time, from its initial formation to a mature structure. Mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
2004-04-17 GO:0048332 mesoderm morphogenesis Added DEFINITION Developmental processes by which the mesoderm is generated and organized. Morphogenesis pertains to the creation of form.
2004-04-17 GO:0048338 mesoderm structural organization Added DEFINITION Biological processes that contribute to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.
2004-04-17 GO:0051019 mitogen-activated protein kinase binding Added DEFINITION Interacting selectively with a mitogen-activated protein kinase.
2004-04-17 GO:0007093 mitotic cell cycle checkpoint Updated DEFINITION A signal transduction based surveillance mechanism that ensures accurate chromosome segregation by preventing premature passage through and exit from mitosis. Events that are monitored include the formation of a correctly assembled spindle, the position of the spindle pole (centrosome) and the orientation of the spindle.
2004-04-17 GO:0007064 mitotic sister chromatid cohesion Updated DEFINITION The physical attachment between sister chromatids that is established during S phase of the mitotic cycle at discrete sites along the entire chromosome, maintained until the metaphase-anaphase transition, and dissolved when sisters separate to opposite poles. This cohesion cycle is critical for high fidelity chromosome transmission.
2004-04-17 GO:0043132 NAD transport Added DEFINITION The directed movement of NAD (nicotinamide adenine dinucleotide) into, out of, within or between cells.
2004-04-17 GO:0048325 negative regulation of axial mesodermal cell fate determination Added DEFINITION Any process that stops, prevents or reduces the rate of axial mesoderm cell fate determination.
2004-04-17 GO:0048329 negative regulation of axial mesodermal cell fate specification Added DEFINITION Any process that stops, prevents or reduces the rate of axial mesoderm cell fate specification.
2004-04-17 GO:0051025 negative regulation of immunoglobulin secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of immunoglobulins from a cell or group of cells.
2004-04-17 GO:0048335 negative regulation of mesodermal cell fate determination Added DEFINITION Any process that stops, prevents or reduces the rate of mesoderm cell fate determination.
2004-04-17 GO:0042662 negative regulation of mesodermal cell fate specification Updated DEFINITION Any process that stops, prevents or reduces the rate of mesoderm cell fate specification.
2004-04-17 GO:0048347 negative regulation of paraxial mesodermal cell fate determination Added DEFINITION Any process that stops, prevents or reduces the rate of paraxial mesoderm cell fate determination.
2004-04-17 GO:0048351 negative regulation of paraxial mesodermal cell fate specification Added DEFINITION Any process that stops, prevents or reduces the rate of paraxial mesoderm cell fate specification.
2004-04-17 GO:0015664 nicotinamide mononucleotide permease activity Updated DEFINITION Catalysis of the transport of nicotinic acid across biological membranes.
2004-04-17 GO:0001846 opsonin binding Added DEFINITION Interacting selectively with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material.
2004-04-17 GO:0001847 opsonin receptor activity Added DEFINITION Combining with an opsonin to initiate a change in cell activity.
2004-04-17 GO:0030916 otic vesicle formation Updated DEFINITION The developmental processes resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.
2004-04-17 GO:0048342 paraxial mesodermal cell differentiation Added DEFINITION Development of the paraxial mesoderm cell type. This will involve the change of a cell or set of cells from one cell identity to another.
2004-04-17 GO:0048343 paraxial mesodermal cell fate commitment Added DEFINITION The process by which a cell becomes committed to become a paraxial mesoderm cell.
2004-04-17 GO:0048344 paraxial mesodermal cell fate determination Added DEFINITION Process involved in paraxial mesoderm cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate into a paraxial mesoderm cell.
2004-04-17 GO:0048348 paraxial mesodermal cell fate specification Added DEFINITION The processes involved in the specification of mesoderm cell identity.
2004-04-17 GO:0048339 paraxial mesoderm development Added DEFINITION Biological processes specifically aimed at the progression of the paraxial mesoderm over time, from its initial formation to a mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.
2004-04-17 GO:0048341 paraxial mesoderm formation Added DEFINITION Biological processes that contribute to the act of giving rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
2004-04-17 GO:0048340 paraxial mesoderm morphogenesis Added DEFINITION Developmental processes by which the paraxial mesoderm is generated and organized. Morphogenesis pertains to the creation of form.
2004-04-17 GO:0048352 paraxial mesoderm structural organization Added DEFINITION Biological processes that contribute to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
2004-04-17 GO:0001864 pentraxin binding Added DEFINITION Interacting selectively with a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.
2004-04-17 GO:0001845 phagolysosome assembly Added DEFINITION The processes involved with the intracellular changes to phagosomes, the vesicles formed by phagocytosis, which include fusion to lysosomes in most cell types.
2004-04-17 GO:0048326 positive regulation of axial mesodermal cell fate determination Added DEFINITION Any process that activates or increases the rate of axial mesoderm cell fate determination.
2004-04-17 GO:0048330 positive regulation of axial mesodermal cell fate specification Added DEFINITION Any process that activates or increases the rate of.
2004-04-17 GO:0051024 positive regulation of immunoglobulin secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of immunoglobulins from a cell or group of cells.
2004-04-17 GO:0043137 DNA replication, removal of RNA primer Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2004-04-17 GO:0030928 dopachrome decarboxylase activity Added DEFINITION Catalysis of the decarboxylation of L-dopachrome to form 5,6-dihydroxyindole.
2004-04-17 GO:0005769 early endosome Updated DEFINITION Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered.
2004-04-17 GO:0051021 GDP-dissociation inhibitor binding Added DEFINITION Interacting selectively with a GDP-dissociation inhibitor protein.
2004-04-17 GO:0001860 complement component C3d receptor activity Added DEFINITION Combining with the C3d product of the complement cascade to initiate a change in cell activity.
2004-04-17 GO:0001853 complement component C3dg binding Added DEFINITION Interacting selectively with the C3dg product of the complement cascade.
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