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GO Term History: Displaying 43 audit records for all terms for the date 2004-04-01

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This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
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All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-04-01 GO:0019637 organophosphate metabolic process Updated DEFINITION The chemical reactions and physical changes involving organophosphates, any phosphate-containing organic compound. They include a number of organophosphorous compounds that were originally developed as nerve gases, but were formerly used as insecticides and anthelmintics, which worked by inhibiting serine proteases.
2004-04-01 GO:0017088 X-Pro dipeptidyl-peptidase activity Updated DEFINITION Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile.
2004-04-01 GO:0006119 oxidative phosphorylation Updated DEFINITION The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2004-04-01 GO:0042712 paternal behavior Updated DEFINITION Male behaviors associated with the care and rearing offspring.
2004-04-01 GO:0006909 phagocytosis Updated DEFINITION The process whereby phagocytes engulf external particulate material by extension and fusion of pseudopods around each particle. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
2004-04-01 GO:0000762 pheromone-induced unidirectional conjugation Updated DEFINITION The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating-types.
2004-04-01 GO:0035030 phosphoinositide 3-kinase complex, class IA Updated DEFINITION A complex containing a heterodimer of a catalytic Class IA phosphoinositide 3-kinase (PI3K) subunit bound to a SH2 domain-containing regulatory (adaptor) subunit. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.
2004-04-01 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep Updated DEFINITION Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
2004-04-01 GO:0030801 positive regulation of cyclic nucleotide metabolic process Updated DEFINITION Any process that activates or increases the rate of cyclic nucleotide metabolism.
2004-04-01 GO:0045089 positive regulation of innate immune response Updated DEFINITION Any process that activates or increases the rate of the innate immune response, the organism's first line of defense against infection.
2004-04-01 GO:0045088 regulation of innate immune response Updated DEFINITION Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
2004-04-01 GO:0000108 repairosome Updated DEFINITION A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of NER, such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage.
2004-04-01 GO:0010202 response to low fluence red light stimulus Updated DEFINITION A change in state or activity of an organism or cell (in terms of movement, secretion, enzyme production, gene expression etc.) as a result of exposure to red light pulses followed by darkness, which occurs at red light levels of 0.001-0.1 mmol/m2/sec and is red/far-red reversible.
2004-04-01 GO:0010047 fruit dehiscence Updated DEFINITION The process leading to the spontaneous opening of the fruit permitting the escape of seeds.
2004-04-01 GO:0016173 ice nucleation inhibitor activity Updated DEFINITION OBSOLETE. Inhibits the formation of ice crystals.
2004-04-01 GO:0000206 inactivation of MAPK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0045087 innate immune response Updated DEFINITION The innate immune response is the first line of defense against infection. It can also activate the adaptive immune response via inflammation as a danger signal that something has damaged the host tissue.
2004-04-01 GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Updated DEFINITION A ligand-dependent receptor found in the nucleus of the cell.
2004-04-01 GO:0000202 MAPKKK cascade during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0042711 maternal behavior Updated DEFINITION Female behaviors associated with the care and rearing offspring.
2004-04-01 GO:0048269 methionine adenosyltransferase complex Updated DEFINITION A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
2004-04-01 GO:0051012 microtubule sliding Added DEFINITION The movement of one microtubule along another microtubule.
2004-04-01 GO:0016256 N-glycan processing to lysosome Updated DEFINITION The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.
2004-04-01 GO:0043116 negative regulation of vascular permeability Updated DEFINITION Any process that reduces the extent to which blood vessels can be pervaded by fluid.
2004-04-01 GO:0000207 nuclear translocation of MAPK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0000110 nucleotide-excision repair factor 1 complex Updated DEFINITION One of several protein complexes involved in nucleotide excision repair; possesses DNA damage recognition and endodeoxynuclease activities.
2004-04-01 GO:0006294 nucleotide-excision repair, preincision complex assembly Updated DEFINITION The assembly of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
2004-04-01 GO:0006293 nucleotide-excision repair, preincision complex stabilization Updated DEFINITION The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
2004-04-01 GO:0000205 activation of MAPK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0000204 activation of MAPKK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0000203 activation of MAPKKK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0015268 alpha-type channel activity Updated DEFINITION Allows the movement of solutes by energy-independent process by passage through a transmembrane aqueous pore. Usually consist of alpha-helical membrane spanners, although beta-strands may be present and contribute to channel.
2004-04-01 GO:0009568 amyloplast starch grain Updated DEFINITION Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
2004-04-01 GO:0009569 chloroplast starch grain Updated DEFINITION Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
2004-04-01 GO:0051012 microtubule sliding Added TERM microtubule sliding
2004-04-01 GO:0030466 chromatin silencing at silent mating-type cassette Added DEFINITION Repression of transcription at silent mating-type loci by the formation of heterochromatin. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2004-04-01 GO:0016343 cytoskeletal anchoring activity Updated DEFINITION OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane.
2004-04-01 GO:0003678 DNA helicase activity Updated DEFINITION Catalysis of the hydrolysis of ATP to unwind the DNA helix at the replication fork, allowing the resulting single strands to be copied.
2004-04-01 GO:0019953 sexual reproduction Updated DEFINITION The regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.
2004-04-01 GO:0043036 starch grain Updated DEFINITION Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
2004-04-01 GO:0005529 sugar binding Updated DEFINITION Interacting selectively with any mono-, di- or trisaccharide carbohydrate.
2004-04-01 GO:0009291 unidirectional conjugation Updated DEFINITION The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating-types.
2004-04-01 GO:0001543 ovarian follicle rupture Updated DEFINITION Disruption of theca cell layer releasing follicular fluid and/or the oocyte.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2004-04-01 GO:0051012 microtubule sliding Added TERM microtubule sliding

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-04-01 GO:0019637 organophosphate metabolic process Updated DEFINITION The chemical reactions and physical changes involving organophosphates, any phosphate-containing organic compound. They include a number of organophosphorous compounds that were originally developed as nerve gases, but were formerly used as insecticides and anthelmintics, which worked by inhibiting serine proteases.
2004-04-01 GO:0017088 X-Pro dipeptidyl-peptidase activity Updated DEFINITION Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile.
2004-04-01 GO:0006119 oxidative phosphorylation Updated DEFINITION The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2004-04-01 GO:0042712 paternal behavior Updated DEFINITION Male behaviors associated with the care and rearing offspring.
2004-04-01 GO:0006909 phagocytosis Updated DEFINITION The process whereby phagocytes engulf external particulate material by extension and fusion of pseudopods around each particle. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
2004-04-01 GO:0000762 pheromone-induced unidirectional conjugation Updated DEFINITION The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating-types.
2004-04-01 GO:0035030 phosphoinositide 3-kinase complex, class IA Updated DEFINITION A complex containing a heterodimer of a catalytic Class IA phosphoinositide 3-kinase (PI3K) subunit bound to a SH2 domain-containing regulatory (adaptor) subunit. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.
2004-04-01 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep Updated DEFINITION Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
2004-04-01 GO:0030801 positive regulation of cyclic nucleotide metabolic process Updated DEFINITION Any process that activates or increases the rate of cyclic nucleotide metabolism.
2004-04-01 GO:0045089 positive regulation of innate immune response Updated DEFINITION Any process that activates or increases the rate of the innate immune response, the organism's first line of defense against infection.
2004-04-01 GO:0045088 regulation of innate immune response Updated DEFINITION Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
2004-04-01 GO:0000108 repairosome Updated DEFINITION A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of NER, such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage.
2004-04-01 GO:0010202 response to low fluence red light stimulus Updated DEFINITION A change in state or activity of an organism or cell (in terms of movement, secretion, enzyme production, gene expression etc.) as a result of exposure to red light pulses followed by darkness, which occurs at red light levels of 0.001-0.1 mmol/m2/sec and is red/far-red reversible.
2004-04-01 GO:0010047 fruit dehiscence Updated DEFINITION The process leading to the spontaneous opening of the fruit permitting the escape of seeds.
2004-04-01 GO:0016173 ice nucleation inhibitor activity Updated DEFINITION OBSOLETE. Inhibits the formation of ice crystals.
2004-04-01 GO:0000206 inactivation of MAPK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0045087 innate immune response Updated DEFINITION The innate immune response is the first line of defense against infection. It can also activate the adaptive immune response via inflammation as a danger signal that something has damaged the host tissue.
2004-04-01 GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Updated DEFINITION A ligand-dependent receptor found in the nucleus of the cell.
2004-04-01 GO:0000202 MAPKKK cascade during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0042711 maternal behavior Updated DEFINITION Female behaviors associated with the care and rearing offspring.
2004-04-01 GO:0048269 methionine adenosyltransferase complex Updated DEFINITION A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
2004-04-01 GO:0051012 microtubule sliding Added DEFINITION The movement of one microtubule along another microtubule.
2004-04-01 GO:0016256 N-glycan processing to lysosome Updated DEFINITION The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.
2004-04-01 GO:0043116 negative regulation of vascular permeability Updated DEFINITION Any process that reduces the extent to which blood vessels can be pervaded by fluid.
2004-04-01 GO:0000207 nuclear translocation of MAPK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0000110 nucleotide-excision repair factor 1 complex Updated DEFINITION One of several protein complexes involved in nucleotide excision repair; possesses DNA damage recognition and endodeoxynuclease activities.
2004-04-01 GO:0006294 nucleotide-excision repair, preincision complex assembly Updated DEFINITION The assembly of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
2004-04-01 GO:0006293 nucleotide-excision repair, preincision complex stabilization Updated DEFINITION The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
2004-04-01 GO:0000205 activation of MAPK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0000204 activation of MAPKK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0000203 activation of MAPKKK during sporulation (sensu Saccharomyces) Updated DEFINITION OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).
2004-04-01 GO:0015268 alpha-type channel activity Updated DEFINITION Allows the movement of solutes by energy-independent process by passage through a transmembrane aqueous pore. Usually consist of alpha-helical membrane spanners, although beta-strands may be present and contribute to channel.
2004-04-01 GO:0009568 amyloplast starch grain Updated DEFINITION Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
2004-04-01 GO:0009569 chloroplast starch grain Updated DEFINITION Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
2004-04-01 GO:0030466 chromatin silencing at silent mating-type cassette Added DEFINITION Repression of transcription at silent mating-type loci by the formation of heterochromatin. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).
2004-04-01 GO:0016343 cytoskeletal anchoring activity Updated DEFINITION OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane.
2004-04-01 GO:0003678 DNA helicase activity Updated DEFINITION Catalysis of the hydrolysis of ATP to unwind the DNA helix at the replication fork, allowing the resulting single strands to be copied.
2004-04-01 GO:0019953 sexual reproduction Updated DEFINITION The regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.
2004-04-01 GO:0043036 starch grain Updated DEFINITION Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
2004-04-01 GO:0005529 sugar binding Updated DEFINITION Interacting selectively with any mono-, di- or trisaccharide carbohydrate.
2004-04-01 GO:0009291 unidirectional conjugation Updated DEFINITION The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating-types.
2004-04-01 GO:0001543 ovarian follicle rupture Updated DEFINITION Disruption of theca cell layer releasing follicular fluid and/or the oocyte.
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