spacer

GO Term History: Displaying 131 audit records for all terms for the date 2004-03-03

From (YYYY-MM-DD):
To (YYYY-MM-DD):
Period:
Category:
Terms:
Limit:
Date Specification

You can specify an explicit date range that you are interested in by setting the "From" and "To" parameters; this will limit the data displayed to those changes that were recorded within that (inclusive) date range.

Alternatively, you can use the "Period" parameter to view the GO term changes that occurred over a specific number of Day(s), Week(s), Month(s) or Year(s) before a specified date.

If you do not enter a "To" date, then the period will be relative to the current date. If, however, you do specify a "To" value, then the "Period" value will display records in the timeframe up to and including that specified date.

Category

You can use this field to specify what types of term changes you are interested in seeing.

Terms

You can enter a list of GO Terms in this field to limit the changes displayed. Please note that only changes made to directly listed terms will be displayed, not term descendants.

Limit

The default number of records returned is 500, however you can increase or decrease this limit. In order to prevent possible browser problems, the maximum upper limit is 10,000.

Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-03-03 GO:0007008 outer mitochondrial membrane organization Updated DEFINITION The assembly and arrangement of the mitochondrial outer membrane (GO:0005741).
2004-03-03 GO:0030723 ovarian fusome organization Updated DEFINITION The assembly and arrangement of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.
2004-03-03 GO:0007031 peroxisome organization Updated DEFINITION The assembly and arrangement of a peroxisome.
2004-03-03 GO:0007009 plasma membrane organization Updated DEFINITION The assembly and arrangement of the plasma membrane.
2004-03-03 GO:0009663 plasmodesma organization Updated DEFINITION The assembly and arrangement of a plasmodesma.
2004-03-03 GO:0009667 plastid inner membrane organization Updated DEFINITION The assembly and arrangement of the inner membrane of a plastid.
2004-03-03 GO:0009668 plastid membrane organization Updated DEFINITION The assembly and arrangement of the membrane of a plastid.
2004-03-03 GO:0009657 plastid organization Updated DEFINITION The assembly and arrangement of a plastid.
2004-03-03 GO:0009666 plastid outer membrane organization Updated DEFINITION The assembly and arrangement of the outer membrane of a plastid.
2004-03-03 GO:0030578 PML body organization Updated DEFINITION The assembly and arrangement of PML bodies (GO:0016605), a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).
2004-03-03 GO:0030719 P granule organization Updated DEFINITION The assembly and arrangement of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
2004-03-03 GO:0048114 polar granule organization and biogenesis (sensu Insecta) Updated DEFINITION The assembly and arrangement of the polar granules, organelles found in the pole plasm of insect cells that contain the necessary constituents for pole plasm assembly.
2004-03-03 GO:0045478 fusome organization Updated DEFINITION The assembly and arrangement of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.
2004-03-03 GO:0010111 glyoxysome organization Updated DEFINITION The assembly and arrangement of the glyoxysome.
2004-03-03 GO:0007030 Golgi organization Updated DEFINITION The assembly and arrangement of the Golgi apparatus.
2004-03-03 GO:0001826 inner cell mass cell differentiation Updated DEFINITION The differentiation of inner cell mass cells (Theiler Stage 4, inner cell mass; EMAP:14).
2004-03-03 GO:0001827 inner cell mass cell fate commitment Updated DEFINITION The cell fate commitment of precursor cells (Theiler Stage 4, compacted morula; EMAP:13)that will become inner cell mass cells (Theiler Stage 4, inner cell mass; EMAP:14).
2004-03-03 GO:0001833 inner cell mass cell proliferation Updated DEFINITION The proliferation of cells in the inner cell mass (Theiler Stage 4, inner cell mass; EMAP:14 |Theiler Stage 5, inner cell mass; EMAP:24).
2004-03-03 GO:0001828 inner cell mass cellular morphogenesis Updated DEFINITION The morphogenesis of cells in the inner cell mass (Theiler Stage 4, inner cell mass; EMAP:14 |Theiler Stage 5, inner cell mass; EMAP:24).
2004-03-03 GO:0007007 inner mitochondrial membrane organization Updated DEFINITION The assembly and arrangement of the mitochondrial inner membrane (GO:0005743).
2004-03-03 GO:0043063 intercellular bridge organization Added DEFINITION The assembly and arrangement of the intracellular bridge.
2004-03-03 GO:0045104 intermediate filament cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures comprising intermediate filaments and their associated proteins.
2004-03-03 GO:0045190 isotype switching Updated DEFINITION The switching of activated B-cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
2004-03-03 GO:0048290 isotype switching to IgA isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0048292 isotype switching to IgD isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0050808 synapse organization Updated DEFINITION The assembly and arrangement of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-03-03 GO:0030724 testicular fusome organization Updated DEFINITION The assembly and arrangement of the fusome of testicular cells, an organelle derived from the spectrosome.
2004-03-03 GO:0010027 thylakoid membrane organization Updated DEFINITION The assembly and arrangement of the thylakoid membrane (GO:0042651).
2004-03-03 GO:0001829 trophectodermal cell differentiation Updated DEFINITION The differentiation of trophectoderm cells (Theiler Stage 4, trophectoderm; EMAP:19).
2004-03-03 GO:0001830 trophectodermal cell fate commitment Updated DEFINITION The cell fate commitment of precursor cells that will become trophectoderm cells (Theiler Stage 4, trophectoderm; EMAP:19).
2004-03-03 GO:0001834 trophectodermal cell proliferation Updated DEFINITION The proliferation of cells in the trophectoderm (Theiler Stage 4, trophectoderm; EMAP:19|Theiler Stage 5, trophectoderm; EMAP:28|Theiler Stage 6, trophectoderm; EMAP:39).
2004-03-03 GO:0001831 trophectodermal cellular morphogenesis Updated DEFINITION The morphogenesis of trophectoderm cells (Theiler Stage 4, trophectoderm; EMAP:19|Theiler Stage 5, trophectoderm; EMAP:28|Theiler Stage 6, trophectoderm; EMAP:39).
2004-03-03 GO:0005031 tumor necrosis factor-activated receptor activity Added DEFINITION Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.
2004-03-03 GO:0007033 vacuole organization Updated DEFINITION The assembly and arrangement of a vacuole.
2004-03-03 GO:0016050 vesicle organization Updated DEFINITION The assembly and arrangement of any vesicle.
2004-03-03 GO:0048298 positive regulation of isotype switching to IgA isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgA isotypes.
2004-03-03 GO:0048301 positive regulation of isotype switching to IgD isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgD isotypes.
2004-03-03 GO:0048295 positive regulation of isotype switching to IgE isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgE isotypes.
2004-03-03 GO:0048304 positive regulation of isotype switching to IgG isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgG isotypes.
2004-03-03 GO:0004674 protein serine/threonine kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.
2004-03-03 GO:0004722 protein serine/threonine phosphatase activity Updated DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2004-03-03 GO:0008287 protein serine/threonine phosphatase complex Updated DEFINITION A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.
2004-03-03 GO:0048296 regulation of isotype switching to IgA isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.
2004-03-03 GO:0048299 regulation of isotype switching to IgD isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.
2004-03-03 GO:0048293 regulation of isotype switching to IgE isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.
2004-03-03 GO:0048302 regulation of isotype switching to IgG isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
2004-03-03 GO:0050791 regulation of physiological process Updated DEFINITION Any process that modulates the frequency, rate or extent of a physiological process, a processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2004-03-03 GO:0043114 regulation of vascular permeability Added DEFINITION Any process that modulates the extent to which blood vessels can be pervaded by fluid.
2004-03-03 GO:0045232 S-layer organization Updated DEFINITION The assembly and arrangement of an S-layer enveloping the cell.
2004-03-03 GO:0045231 slime layer organization Updated DEFINITION The assembly and arrangement of a slime layer enveloping the cell.
2004-03-03 GO:0030721 spectrosome organization Updated DEFINITION The assembly and arrangement of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.
2004-03-03 GO:0030382 sperm mitochondrion organization Updated DEFINITION The assembly and arrangement of sperm mitochondria; the process by which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.
2004-03-03 GO:0048289 isotype switching to IgE isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0048291 isotype switching to IgG isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0030577 Lands organization Updated DEFINITION The assembly and arrangement of Lands (GO:0016606), a class of nuclear body that react against SP140 auto-antibodies.
2004-03-03 GO:0009659 leucoplast organization Added DEFINITION The assembly and arrangement of the leucoplast.
2004-03-03 GO:0007040 lysosome organization Updated DEFINITION The assembly and arrangement of lysosomes.
2004-03-03 GO:0016044 cellular membrane organization Updated DEFINITION The assembly and arrangement of membranes inside and surrounding the cell.
2004-03-03 GO:0000226 microtubule cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures comprising microtubules and their associated proteins.
2004-03-03 GO:0007006 mitochondrial membrane organization Updated DEFINITION The assembly and arrangement of the mitochondrial membrane, the lipid bilayer surrounding a mitochondrion.
2004-03-03 GO:0007005 mitochondrion organization Updated DEFINITION The assembly and arrangement of a mitochondrion.
2004-03-03 GO:0048297 negative regulation of isotype switching to IgA isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgA isotypes.
2004-03-03 GO:0048300 negative regulation of isotype switching to IgD isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgD isotypes.
2004-03-03 GO:0048294 negative regulation of isotype switching to IgE isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgE isotypes.
2004-03-03 GO:0043118 negative regulation of physiological process Added DEFINITION Any process that stops, prevents or reduces the rate of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2004-03-03 GO:0043116 negative regulation of vascular permeability Added DEFINITION Any process that reduces the the extent to which blood vessels can be pervaded by fluid.
2004-03-03 GO:0043121 neurotrophin binding Added DEFINITION Interacting selectively with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth.
2004-03-03 GO:0043119 positive regulation of physiological process Added DEFINITION Any process that activates or increases the rate of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2004-03-03 GO:0043117 positive regulation of vascular permeability Added DEFINITION Any process that increases the extent to which blood vessels can be pervaded by fluid.
2004-03-03 GO:0043120 tumor necrosis factor binding Added DEFINITION Interacting selectively with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.
2004-03-03 GO:0001825 blastocyst formation Updated DEFINITION The initial formation of a blastocyst from a solid ball of cells known as a morula (Theiler Stage 3, compacted morula; EMAP:9.).
2004-03-03 GO:0001832 blastocyst growth Updated DEFINITION An increase in size of a blastocyst due to expansion of the blastocoelic cavity (Theiler Stage 4, blastocoelic cavity; EMAP:17|Theiler Stage 5, blastocoelic cavity; EMAP:27|Theiler Stage 6, blastocoelic cavity; EMAP:36) cell shape changes, and cell proliferation.
2004-03-03 GO:0001835 blastocyst hatching Updated DEFINITION The hatching of the cellular blastocyst from the zona pellucida (Theiler Stage 4, zona pellucida; EMAP:22|Theiler Stage 5, embryo; EMAP:23).
2004-03-03 GO:0030576 Cajal body organization Updated DEFINITION The assembly and arrangement of Cajal bodies (GO:0015030), nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.
2004-03-03 GO:0045230 capsule organization Updated DEFINITION The assembly and arrangement of the capsule, a protective structure surrounding some species of bacteria and fungi.
2004-03-03 GO:0016043 cellular component organization Updated DEFINITION Any cellular process involved in the assembly and arrangement of structures within a cell.
2004-03-03 GO:0030030 cell projection organization Updated DEFINITION The assembly and arrangement of a prolongation or process extending from a cell eg. a flagellum or axon.
2004-03-03 GO:0007047 cellular cell wall organization Updated DEFINITION The assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
2004-03-03 GO:0009664 plant-type cell wall organization Added DEFINITION The assembly and arrangement of the cell wall; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).
2004-03-03 GO:0009658 chloroplast organization Added DEFINITION The assembly and arrangement of the chloroplast.
2004-03-03 GO:0009661 chromoplast organization Added DEFINITION The assembly and arrangement of the chromoplast.
2004-03-03 GO:0007001 chromosome organization and biogenesis (sensu Eukaryota) Updated DEFINITION The assembly and arrangement of the eukaryotic chromosomes, structures composed of a very long molecule of DNA and associated proteins (e. g. histones) that carries hereditary information.
2004-03-03 GO:0030866 cortical actin cytoskeleton organization Updated DEFINITION The assembly and arrangement of actin-based cytoskeletal structures in the cell cortex, i. e. just beneath the plasma membrane.
2004-03-03 GO:0030865 cortical cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures in the cell cortex, i. e. just beneath the plasma membrane.
2004-03-03 GO:0007028 cytoplasm organization Updated DEFINITION The assembly and arrangement of the cytoplasm and its components.
2004-03-03 GO:0007010 cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures.
2004-03-03 GO:0007032 endosome organization Updated DEFINITION The assembly and arrangement of endosomes.
2004-03-03 GO:0007029 endoplasmic reticulum organization Updated DEFINITION The assembly and arrangement of the endoplasmic reticulum.
2004-03-03 GO:0009662 etioplast organization Added DEFINITION The assembly and arrangement of the etioplast.
2004-03-03 GO:0045229 external encapsulating structure organization Updated DEFINITION The assembly and arrangement of external structures that lie outside the plasma membrane and surround the entire cell.
2004-03-03 GO:0030198 extracellular matrix organization Updated DEFINITION The assembly and arrangement of an extracellular matrix.
2004-03-03 GO:0043062 extracellular structure organization Updated DEFINITION The assembly and arrangement of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
2004-03-03 GO:0043064 flagellum organization Updated DEFINITION The assembly and arrangement of a flagellum, a long thin projection from a cell, used in movement.
2004-03-03 GO:0048303 negative regulation of isotype switching to IgG isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgG isotypes.
2004-03-03 GO:0005030 neurotrophin receptor activity Added DEFINITION Combining with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth, to initiate a change in cell activity.
2004-03-03 GO:0005027 NGF/TNF (6 C-domain) receptor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-03-03 GO:0030575 nuclear body organization Updated DEFINITION The assembly and arrangement of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
2004-03-03 GO:0006998 nuclear envelope organization Updated DEFINITION The assembly and arrangement of the nuclear membrane.
2004-03-03 GO:0006997 nucleus organization Updated DEFINITION The assembly and arrangement of the nucleus.
2004-03-03 GO:0006999 nuclear pore organization Added DEFINITION The assembly and arrangement of the nuclear pore.
2004-03-03 GO:0035063 nuclear speck organization Updated DEFINITION The assembly and arrangement of nuclear specks (GO:0016607), a class of nuclear body in which splicing factors are localized.
2004-03-03 GO:0007000 nucleolus organization Added DEFINITION The assembly and arrangement of the nucleolus.
2004-03-03 GO:0006996 organelle organization Updated DEFINITION The assembly and arrangement of any organelle within a cell.
2004-03-03 GO:0001824 blastocyst development Updated DEFINITION The formation and subsequent development of the mammalian blastocyst (Theiler Stage 5, embryo; EMAP:23), a hollow ball of cells containing two cell types, the inner cell mass (Theiler Stage 5, inner cell mass; EMAP:24) and the trophectoderm (Theiler Stage 5, trophectoderm; EMAP:28).
2004-03-03 GO:0030036 actin cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures comprising actin filaments and their associated proteins.
2004-03-03 GO:0009660 amyloplast organization Added DEFINITION The assembly and arrangement of amyloplasts.
2004-03-03 GO:0048305 immunoglobulin secretion Added DEFINITION The regulated release of immunoglobulins from a B- cell, whose mechanism includes the use of alternate polyadenylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin.
2004-03-03 GO:0005030 neurotrophin receptor activity Updated TERM neurotrophin receptor activity
2004-03-03 GO:0043116 negative regulation of vascular permeability Added TERM negative regulation of vascular permeability
2004-03-03 GO:0043117 positive regulation of vascular permeability Added TERM positive regulation of vascular permeability
2004-03-03 GO:0043118 negative regulation of physiological process Added TERM negative regulation of physiological process
2004-03-03 GO:0043119 positive regulation of physiological process Added TERM positive regulation of physiological process
2004-03-03 GO:0043120 tumor necrosis factor binding Added TERM tumor necrosis factor binding
2004-03-03 GO:0048289 isotype switching to IgE isotypes Added TERM isotype switching to IgE isotypes
2004-03-03 GO:0048290 isotype switching to IgA isotypes Added TERM isotype switching to IgA isotypes
2004-03-03 GO:0048291 isotype switching to IgG isotypes Added TERM isotype switching to IgG isotypes
2004-03-03 GO:0048292 isotype switching to IgD isotypes Added TERM isotype switching to IgD isotypes
2004-03-03 GO:0048293 regulation of isotype switching to IgE isotypes Added TERM regulation of isotype switching to IgE isotypes
2004-03-03 GO:0048294 negative regulation of isotype switching to IgE isotypes Added TERM negative regulation of isotype switching to IgE isotypes
2004-03-03 GO:0048295 positive regulation of isotype switching to IgE isotypes Added TERM positive regulation of isotype switching to IgE isotypes
2004-03-03 GO:0048296 regulation of isotype switching to IgA isotypes Added TERM regulation of isotype switching to IgA isotypes
2004-03-03 GO:0048297 negative regulation of isotype switching to IgA isotypes Added TERM negative regulation of isotype switching to IgA isotypes
2004-03-03 GO:0048298 positive regulation of isotype switching to IgA isotypes Added TERM positive regulation of isotype switching to IgA isotypes
2004-03-03 GO:0048299 regulation of isotype switching to IgD isotypes Added TERM regulation of isotype switching to IgD isotypes
2004-03-03 GO:0048300 negative regulation of isotype switching to IgD isotypes Added TERM negative regulation of isotype switching to IgD isotypes
2004-03-03 GO:0048301 positive regulation of isotype switching to IgD isotypes Added TERM positive regulation of isotype switching to IgD isotypes
2004-03-03 GO:0048302 regulation of isotype switching to IgG isotypes Added TERM regulation of isotype switching to IgG isotypes
2004-03-03 GO:0048303 negative regulation of isotype switching to IgG isotypes Added TERM negative regulation of isotype switching to IgG isotypes
2004-03-03 GO:0048304 positive regulation of isotype switching to IgG isotypes Added TERM positive regulation of isotype switching to IgG isotypes
2004-03-03 GO:0048305 immunoglobulin secretion Added TERM immunoglobulin secretion
2004-03-03 GO:0043121 neurotrophin binding Added TERM neurotrophin binding

Terms

Timestamp GO ID GO Term Name Action Category Detail
2004-03-03 GO:0005030 neurotrophin receptor activity Updated TERM neurotrophin receptor activity
2004-03-03 GO:0043116 negative regulation of vascular permeability Added TERM negative regulation of vascular permeability
2004-03-03 GO:0043117 positive regulation of vascular permeability Added TERM positive regulation of vascular permeability
2004-03-03 GO:0043118 negative regulation of physiological process Added TERM negative regulation of physiological process
2004-03-03 GO:0043119 positive regulation of physiological process Added TERM positive regulation of physiological process
2004-03-03 GO:0043120 tumor necrosis factor binding Added TERM tumor necrosis factor binding
2004-03-03 GO:0048289 isotype switching to IgE isotypes Added TERM isotype switching to IgE isotypes
2004-03-03 GO:0048290 isotype switching to IgA isotypes Added TERM isotype switching to IgA isotypes
2004-03-03 GO:0048291 isotype switching to IgG isotypes Added TERM isotype switching to IgG isotypes
2004-03-03 GO:0048292 isotype switching to IgD isotypes Added TERM isotype switching to IgD isotypes
2004-03-03 GO:0048293 regulation of isotype switching to IgE isotypes Added TERM regulation of isotype switching to IgE isotypes
2004-03-03 GO:0048294 negative regulation of isotype switching to IgE isotypes Added TERM negative regulation of isotype switching to IgE isotypes
2004-03-03 GO:0048295 positive regulation of isotype switching to IgE isotypes Added TERM positive regulation of isotype switching to IgE isotypes
2004-03-03 GO:0048296 regulation of isotype switching to IgA isotypes Added TERM regulation of isotype switching to IgA isotypes
2004-03-03 GO:0048297 negative regulation of isotype switching to IgA isotypes Added TERM negative regulation of isotype switching to IgA isotypes
2004-03-03 GO:0048298 positive regulation of isotype switching to IgA isotypes Added TERM positive regulation of isotype switching to IgA isotypes
2004-03-03 GO:0048299 regulation of isotype switching to IgD isotypes Added TERM regulation of isotype switching to IgD isotypes
2004-03-03 GO:0048300 negative regulation of isotype switching to IgD isotypes Added TERM negative regulation of isotype switching to IgD isotypes
2004-03-03 GO:0048301 positive regulation of isotype switching to IgD isotypes Added TERM positive regulation of isotype switching to IgD isotypes
2004-03-03 GO:0048302 regulation of isotype switching to IgG isotypes Added TERM regulation of isotype switching to IgG isotypes
2004-03-03 GO:0048303 negative regulation of isotype switching to IgG isotypes Added TERM negative regulation of isotype switching to IgG isotypes
2004-03-03 GO:0048304 positive regulation of isotype switching to IgG isotypes Added TERM positive regulation of isotype switching to IgG isotypes
2004-03-03 GO:0048305 immunoglobulin secretion Added TERM immunoglobulin secretion
2004-03-03 GO:0043121 neurotrophin binding Added TERM neurotrophin binding

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-03-03 GO:0007008 outer mitochondrial membrane organization Updated DEFINITION The assembly and arrangement of the mitochondrial outer membrane (GO:0005741).
2004-03-03 GO:0030723 ovarian fusome organization Updated DEFINITION The assembly and arrangement of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.
2004-03-03 GO:0007031 peroxisome organization Updated DEFINITION The assembly and arrangement of a peroxisome.
2004-03-03 GO:0007009 plasma membrane organization Updated DEFINITION The assembly and arrangement of the plasma membrane.
2004-03-03 GO:0009663 plasmodesma organization Updated DEFINITION The assembly and arrangement of a plasmodesma.
2004-03-03 GO:0009667 plastid inner membrane organization Updated DEFINITION The assembly and arrangement of the inner membrane of a plastid.
2004-03-03 GO:0009668 plastid membrane organization Updated DEFINITION The assembly and arrangement of the membrane of a plastid.
2004-03-03 GO:0009657 plastid organization Updated DEFINITION The assembly and arrangement of a plastid.
2004-03-03 GO:0009666 plastid outer membrane organization Updated DEFINITION The assembly and arrangement of the outer membrane of a plastid.
2004-03-03 GO:0030578 PML body organization Updated DEFINITION The assembly and arrangement of PML bodies (GO:0016605), a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).
2004-03-03 GO:0030719 P granule organization Updated DEFINITION The assembly and arrangement of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
2004-03-03 GO:0048114 polar granule organization and biogenesis (sensu Insecta) Updated DEFINITION The assembly and arrangement of the polar granules, organelles found in the pole plasm of insect cells that contain the necessary constituents for pole plasm assembly.
2004-03-03 GO:0045478 fusome organization Updated DEFINITION The assembly and arrangement of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.
2004-03-03 GO:0010111 glyoxysome organization Updated DEFINITION The assembly and arrangement of the glyoxysome.
2004-03-03 GO:0007030 Golgi organization Updated DEFINITION The assembly and arrangement of the Golgi apparatus.
2004-03-03 GO:0001826 inner cell mass cell differentiation Updated DEFINITION The differentiation of inner cell mass cells (Theiler Stage 4, inner cell mass; EMAP:14).
2004-03-03 GO:0001827 inner cell mass cell fate commitment Updated DEFINITION The cell fate commitment of precursor cells (Theiler Stage 4, compacted morula; EMAP:13)that will become inner cell mass cells (Theiler Stage 4, inner cell mass; EMAP:14).
2004-03-03 GO:0001833 inner cell mass cell proliferation Updated DEFINITION The proliferation of cells in the inner cell mass (Theiler Stage 4, inner cell mass; EMAP:14 |Theiler Stage 5, inner cell mass; EMAP:24).
2004-03-03 GO:0001828 inner cell mass cellular morphogenesis Updated DEFINITION The morphogenesis of cells in the inner cell mass (Theiler Stage 4, inner cell mass; EMAP:14 |Theiler Stage 5, inner cell mass; EMAP:24).
2004-03-03 GO:0007007 inner mitochondrial membrane organization Updated DEFINITION The assembly and arrangement of the mitochondrial inner membrane (GO:0005743).
2004-03-03 GO:0043063 intercellular bridge organization Added DEFINITION The assembly and arrangement of the intracellular bridge.
2004-03-03 GO:0045104 intermediate filament cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures comprising intermediate filaments and their associated proteins.
2004-03-03 GO:0045190 isotype switching Updated DEFINITION The switching of activated B-cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
2004-03-03 GO:0048290 isotype switching to IgA isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0048292 isotype switching to IgD isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0050808 synapse organization Updated DEFINITION The assembly and arrangement of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-03-03 GO:0030724 testicular fusome organization Updated DEFINITION The assembly and arrangement of the fusome of testicular cells, an organelle derived from the spectrosome.
2004-03-03 GO:0010027 thylakoid membrane organization Updated DEFINITION The assembly and arrangement of the thylakoid membrane (GO:0042651).
2004-03-03 GO:0001829 trophectodermal cell differentiation Updated DEFINITION The differentiation of trophectoderm cells (Theiler Stage 4, trophectoderm; EMAP:19).
2004-03-03 GO:0001830 trophectodermal cell fate commitment Updated DEFINITION The cell fate commitment of precursor cells that will become trophectoderm cells (Theiler Stage 4, trophectoderm; EMAP:19).
2004-03-03 GO:0001834 trophectodermal cell proliferation Updated DEFINITION The proliferation of cells in the trophectoderm (Theiler Stage 4, trophectoderm; EMAP:19|Theiler Stage 5, trophectoderm; EMAP:28|Theiler Stage 6, trophectoderm; EMAP:39).
2004-03-03 GO:0001831 trophectodermal cellular morphogenesis Updated DEFINITION The morphogenesis of trophectoderm cells (Theiler Stage 4, trophectoderm; EMAP:19|Theiler Stage 5, trophectoderm; EMAP:28|Theiler Stage 6, trophectoderm; EMAP:39).
2004-03-03 GO:0005031 tumor necrosis factor-activated receptor activity Added DEFINITION Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.
2004-03-03 GO:0007033 vacuole organization Updated DEFINITION The assembly and arrangement of a vacuole.
2004-03-03 GO:0016050 vesicle organization Updated DEFINITION The assembly and arrangement of any vesicle.
2004-03-03 GO:0048298 positive regulation of isotype switching to IgA isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgA isotypes.
2004-03-03 GO:0048301 positive regulation of isotype switching to IgD isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgD isotypes.
2004-03-03 GO:0048295 positive regulation of isotype switching to IgE isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgE isotypes.
2004-03-03 GO:0048304 positive regulation of isotype switching to IgG isotypes Added DEFINITION Any process that activates or increases the rate of isotype switching to IgG isotypes.
2004-03-03 GO:0004674 protein serine/threonine kinase activity Updated DEFINITION Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.
2004-03-03 GO:0004722 protein serine/threonine phosphatase activity Updated DEFINITION Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
2004-03-03 GO:0008287 protein serine/threonine phosphatase complex Updated DEFINITION A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.
2004-03-03 GO:0048296 regulation of isotype switching to IgA isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.
2004-03-03 GO:0048299 regulation of isotype switching to IgD isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.
2004-03-03 GO:0048293 regulation of isotype switching to IgE isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.
2004-03-03 GO:0048302 regulation of isotype switching to IgG isotypes Added DEFINITION Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
2004-03-03 GO:0050791 regulation of physiological process Updated DEFINITION Any process that modulates the frequency, rate or extent of a physiological process, a processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2004-03-03 GO:0043114 regulation of vascular permeability Added DEFINITION Any process that modulates the extent to which blood vessels can be pervaded by fluid.
2004-03-03 GO:0045232 S-layer organization Updated DEFINITION The assembly and arrangement of an S-layer enveloping the cell.
2004-03-03 GO:0045231 slime layer organization Updated DEFINITION The assembly and arrangement of a slime layer enveloping the cell.
2004-03-03 GO:0030721 spectrosome organization Updated DEFINITION The assembly and arrangement of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.
2004-03-03 GO:0030382 sperm mitochondrion organization Updated DEFINITION The assembly and arrangement of sperm mitochondria; the process by which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.
2004-03-03 GO:0048289 isotype switching to IgE isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0048291 isotype switching to IgG isotypes Added DEFINITION The switching of activated B-cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.
2004-03-03 GO:0030577 Lands organization Updated DEFINITION The assembly and arrangement of Lands (GO:0016606), a class of nuclear body that react against SP140 auto-antibodies.
2004-03-03 GO:0009659 leucoplast organization Added DEFINITION The assembly and arrangement of the leucoplast.
2004-03-03 GO:0007040 lysosome organization Updated DEFINITION The assembly and arrangement of lysosomes.
2004-03-03 GO:0016044 cellular membrane organization Updated DEFINITION The assembly and arrangement of membranes inside and surrounding the cell.
2004-03-03 GO:0000226 microtubule cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures comprising microtubules and their associated proteins.
2004-03-03 GO:0007006 mitochondrial membrane organization Updated DEFINITION The assembly and arrangement of the mitochondrial membrane, the lipid bilayer surrounding a mitochondrion.
2004-03-03 GO:0007005 mitochondrion organization Updated DEFINITION The assembly and arrangement of a mitochondrion.
2004-03-03 GO:0048297 negative regulation of isotype switching to IgA isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgA isotypes.
2004-03-03 GO:0048300 negative regulation of isotype switching to IgD isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgD isotypes.
2004-03-03 GO:0048294 negative regulation of isotype switching to IgE isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgE isotypes.
2004-03-03 GO:0043118 negative regulation of physiological process Added DEFINITION Any process that stops, prevents or reduces the rate of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2004-03-03 GO:0043116 negative regulation of vascular permeability Added DEFINITION Any process that reduces the the extent to which blood vessels can be pervaded by fluid.
2004-03-03 GO:0043121 neurotrophin binding Added DEFINITION Interacting selectively with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth.
2004-03-03 GO:0043119 positive regulation of physiological process Added DEFINITION Any process that activates or increases the rate of a physiological process, a process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms.
2004-03-03 GO:0043117 positive regulation of vascular permeability Added DEFINITION Any process that increases the extent to which blood vessels can be pervaded by fluid.
2004-03-03 GO:0043120 tumor necrosis factor binding Added DEFINITION Interacting selectively with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.
2004-03-03 GO:0001825 blastocyst formation Updated DEFINITION The initial formation of a blastocyst from a solid ball of cells known as a morula (Theiler Stage 3, compacted morula; EMAP:9.).
2004-03-03 GO:0001832 blastocyst growth Updated DEFINITION An increase in size of a blastocyst due to expansion of the blastocoelic cavity (Theiler Stage 4, blastocoelic cavity; EMAP:17|Theiler Stage 5, blastocoelic cavity; EMAP:27|Theiler Stage 6, blastocoelic cavity; EMAP:36) cell shape changes, and cell proliferation.
2004-03-03 GO:0001835 blastocyst hatching Updated DEFINITION The hatching of the cellular blastocyst from the zona pellucida (Theiler Stage 4, zona pellucida; EMAP:22|Theiler Stage 5, embryo; EMAP:23).
2004-03-03 GO:0030576 Cajal body organization Updated DEFINITION The assembly and arrangement of Cajal bodies (GO:0015030), nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.
2004-03-03 GO:0045230 capsule organization Updated DEFINITION The assembly and arrangement of the capsule, a protective structure surrounding some species of bacteria and fungi.
2004-03-03 GO:0016043 cellular component organization Updated DEFINITION Any cellular process involved in the assembly and arrangement of structures within a cell.
2004-03-03 GO:0030030 cell projection organization Updated DEFINITION The assembly and arrangement of a prolongation or process extending from a cell eg. a flagellum or axon.
2004-03-03 GO:0007047 cellular cell wall organization Updated DEFINITION The assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
2004-03-03 GO:0009664 plant-type cell wall organization Added DEFINITION The assembly and arrangement of the cell wall; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).
2004-03-03 GO:0009658 chloroplast organization Added DEFINITION The assembly and arrangement of the chloroplast.
2004-03-03 GO:0009661 chromoplast organization Added DEFINITION The assembly and arrangement of the chromoplast.
2004-03-03 GO:0007001 chromosome organization and biogenesis (sensu Eukaryota) Updated DEFINITION The assembly and arrangement of the eukaryotic chromosomes, structures composed of a very long molecule of DNA and associated proteins (e. g. histones) that carries hereditary information.
2004-03-03 GO:0030866 cortical actin cytoskeleton organization Updated DEFINITION The assembly and arrangement of actin-based cytoskeletal structures in the cell cortex, i. e. just beneath the plasma membrane.
2004-03-03 GO:0030865 cortical cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures in the cell cortex, i. e. just beneath the plasma membrane.
2004-03-03 GO:0007028 cytoplasm organization Updated DEFINITION The assembly and arrangement of the cytoplasm and its components.
2004-03-03 GO:0007010 cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures.
2004-03-03 GO:0007032 endosome organization Updated DEFINITION The assembly and arrangement of endosomes.
2004-03-03 GO:0007029 endoplasmic reticulum organization Updated DEFINITION The assembly and arrangement of the endoplasmic reticulum.
2004-03-03 GO:0009662 etioplast organization Added DEFINITION The assembly and arrangement of the etioplast.
2004-03-03 GO:0045229 external encapsulating structure organization Updated DEFINITION The assembly and arrangement of external structures that lie outside the plasma membrane and surround the entire cell.
2004-03-03 GO:0030198 extracellular matrix organization Updated DEFINITION The assembly and arrangement of an extracellular matrix.
2004-03-03 GO:0043062 extracellular structure organization Updated DEFINITION The assembly and arrangement of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
2004-03-03 GO:0043064 flagellum organization Updated DEFINITION The assembly and arrangement of a flagellum, a long thin projection from a cell, used in movement.
2004-03-03 GO:0048303 negative regulation of isotype switching to IgG isotypes Added DEFINITION Any process that stops, prevents or reduces the rate of isotype switching to IgG isotypes.
2004-03-03 GO:0005030 neurotrophin receptor activity Added DEFINITION Combining with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth, to initiate a change in cell activity.
2004-03-03 GO:0005027 NGF/TNF (6 C-domain) receptor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-03-03 GO:0030575 nuclear body organization Updated DEFINITION The assembly and arrangement of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
2004-03-03 GO:0006998 nuclear envelope organization Updated DEFINITION The assembly and arrangement of the nuclear membrane.
2004-03-03 GO:0006997 nucleus organization Updated DEFINITION The assembly and arrangement of the nucleus.
2004-03-03 GO:0006999 nuclear pore organization Added DEFINITION The assembly and arrangement of the nuclear pore.
2004-03-03 GO:0035063 nuclear speck organization Updated DEFINITION The assembly and arrangement of nuclear specks (GO:0016607), a class of nuclear body in which splicing factors are localized.
2004-03-03 GO:0007000 nucleolus organization Added DEFINITION The assembly and arrangement of the nucleolus.
2004-03-03 GO:0006996 organelle organization Updated DEFINITION The assembly and arrangement of any organelle within a cell.
2004-03-03 GO:0001824 blastocyst development Updated DEFINITION The formation and subsequent development of the mammalian blastocyst (Theiler Stage 5, embryo; EMAP:23), a hollow ball of cells containing two cell types, the inner cell mass (Theiler Stage 5, inner cell mass; EMAP:24) and the trophectoderm (Theiler Stage 5, trophectoderm; EMAP:28).
2004-03-03 GO:0030036 actin cytoskeleton organization Updated DEFINITION The assembly and arrangement of cytoskeletal structures comprising actin filaments and their associated proteins.
2004-03-03 GO:0009660 amyloplast organization Added DEFINITION The assembly and arrangement of amyloplasts.
2004-03-03 GO:0048305 immunoglobulin secretion Added DEFINITION The regulated release of immunoglobulins from a B- cell, whose mechanism includes the use of alternate polyadenylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin.
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
305ms