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GO Term History: Displaying 134 audit records for all terms for the date 2004-01-22

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-01-22 GO:0005026 transforming growth factor beta receptor activity, type II Updated TERM type II transforming growth factor beta receptor activity
2004-01-22 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, cytoplasmic mediator activity
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Updated TERM transforming growth factor beta receptor binding
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Updated TERM positive regulation of transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Updated TERM negative regulation of transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Updated TERM regulation of transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0017028 obsolete protein stabilization activity Updated DEFINITION OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds.
2004-01-22 GO:0008638 obsolete protein tagging activity Updated DEFINITION OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e. g. degradation.
2004-01-22 GO:0050818 regulation of coagulation Added DEFINITION Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
2004-01-22 GO:0050828 regulation of liquid surface tension Added DEFINITION Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.
2004-01-22 GO:0050826 response to freezing Added DEFINITION A change in state or activity of an organism (in terms of movement, secretion, gene expression, enzyme production, etc.) in response to temperatures below 0 degrees Celsius.
2004-01-22 GO:0019214 obsolete surfactant activity Updated DEFINITION OBSOLETE. The action of reducing the surface tension of a liquid.
2004-01-22 GO:0015070 obsolete toxin activity Updated DEFINITION OBSOLETE. Acts as to cause injury to other living organisms.
2004-01-22 GO:0050827 toxin receptor binding Added DEFINITION Interacting selectively with a toxin receptor, a receptor for substances that cause injury to living organisms.
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Updated DEFINITION Interacting selectively with the transforming growth factor alpha receptor.
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Updated DEFINITION Interacting selectively with the transforming growth factor beta receptor.
2004-01-22 GO:0050824 water binding Added DEFINITION Interacting selectively with water (H2O).
2004-01-22 GO:0016172 obsolete antifreeze activity Updated DEFINITION OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (eg. blood) at below freezing exogenous temperatures.
2004-01-22 GO:0003800 obsolete antiviral response protein activity Added DEFINITION OBSOLETE. A protein involved in an antiviral response.
2004-01-22 GO:0016506 obsolete apoptosis activator activity Updated DEFINITION OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.
2004-01-22 GO:0008189 obsolete apoptosis inhibitor activity Updated DEFINITION OBSOLETE. The function held by products which directly block any step in the process of apoptosis.
2004-01-22 GO:0016329 obsolete apoptosis regulator activity Updated DEFINITION OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.
2004-01-22 GO:0017030 obsolete beta-galactosidase stabilization activity Added DEFINITION OBSOLETE. Stabilization of the structure of beta-galactosidase.
2004-01-22 GO:0003801 obsolete blood coagulation factor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-01-22 GO:0042280 obsolete cell surface antigen activity, host-interacting Updated DEFINITION OBSOLETE. Functions as an immunogenic target for the host immune system that masks other invariant surface molecules from immune recognition.
2004-01-22 GO:0050817 coagulation Added DEFINITION The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
2004-01-22 GO:0003811 obsolete complement activity Updated DEFINITION OBSOLETE. Any of a set of activities involved in the complement cascade.
2004-01-22 GO:0030009 obsolete complement factor H activity Updated DEFINITION OBSOLETE. A cofactor for the serine protease complement factor I.
2004-01-22 GO:0003793 obsolete defense/immunity protein activity Updated DEFINITION OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease.
2004-01-22 GO:0008025 obsolete diazepam binding inhibitor activity Updated DEFINITION OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters.
2004-01-22 GO:0050825 ice binding Added DEFINITION Interacting selectively with ice, water reduced to the solid state by cold temperature. It is a white or transparent colourless substance, crystalline, brittle, and viscoidal.
2004-01-22 GO:0019833 obsolete ice nucleation activity Updated DEFINITION OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation (see GO:0019833).
2004-01-22 GO:0016173 obsolete ice nucleation inhibitor activity Updated DEFINITION OBSOLETE. Inhibits the the formation of ice crystals.
2004-01-22 GO:0050819 negative regulation of coagulation Added DEFINITION Any process that stops, prevents or reduces the rate of coagulation.
2004-01-22 GO:0050823 peptide antigen stabilization Added DEFINITION The processes involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.
2004-01-22 GO:0048192 obsolete peptide antigen stabilization activity Updated DEFINITION OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell.
2004-01-22 GO:0050822 peptide stabilization Added DEFINITION The processes involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.
2004-01-22 GO:0048191 obsolete peptide stabilization activity Updated DEFINITION OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
2004-01-22 GO:0050815 phosphoserine residue binding Added DEFINITION Interacting selectively with a phosphorylated serine residue within a protein.
2004-01-22 GO:0045310 obsolete phosphoserine/phosphothreonine binding Updated DEFINITION OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein.
2004-01-22 GO:0050816 phosphothreonine residue binding Added DEFINITION Interacting selectively with a phosphorylated threonine residue within a protein.
2004-01-22 GO:0003794 obsolete acute-phase response protein activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-01-22 GO:0008435 obsolete anticoagulant activity Updated DEFINITION OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation.
2004-01-22 GO:0043065 positive regulation of apoptotic process Updated TERM positive regulation of apoptosis
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Updated TERM transforming growth factor beta receptor anchoring activity
2004-01-22 GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
2004-01-22 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
2004-01-22 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
2004-01-22 GO:0050815 phosphoserine residue binding Added TERM phosphoserine binding
2004-01-22 GO:0050816 phosphothreonine residue binding Added TERM phosphothreonine binding
2004-01-22 GO:0050817 coagulation Added TERM coagulation
2004-01-22 GO:0050818 regulation of coagulation Added TERM regulation of coagulation
2004-01-22 GO:0050819 negative regulation of coagulation Added TERM negative regulation of coagulation
2004-01-22 GO:0050820 positive regulation of coagulation Added TERM positive regulation of coagulation
2004-01-22 GO:0050821 protein stabilization Added TERM protein stabilization
2004-01-22 GO:0050822 peptide stabilization Added TERM peptide stabilization
2004-01-22 GO:0050823 peptide antigen stabilization Added TERM peptide antigen stabilization
2004-01-22 GO:0050824 water binding Added TERM water binding
2004-01-22 GO:0050825 ice binding Added TERM ice binding
2004-01-22 GO:0050826 response to freezing Added TERM response to freezing
2004-01-22 GO:0050827 toxin receptor binding Added TERM toxin receptor binding
2004-01-22 GO:0050828 regulation of liquid surface tension Added TERM regulation of liquid surface tension
2004-01-22 GO:0050431 transforming growth factor beta binding Updated TERM transforming growth factor beta binding
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Updated TERM transforming growth factor alpha receptor binding
2004-01-22 GO:0008259 obsolete transforming growth factor beta ligand binding to type I receptor Updated TERM transforming growth factor beta ligand binding to type I receptor
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Updated TERM transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0007180 obsolete transforming growth factor beta ligand binding to type II receptor Updated TERM transforming growth factor beta ligand binding to type II receptor
2004-01-22 GO:0007181 transforming growth factor beta receptor complex assembly Updated TERM transforming growth factor beta receptor complex assembly
2004-01-22 GO:0005024 transforming growth factor beta-activated receptor activity Updated TERM transforming growth factor beta receptor activity
2004-01-22 GO:0005025 transforming growth factor beta receptor activity, type I Updated TERM type I transforming growth factor beta receptor activity
2004-01-22 GO:0005026 transforming growth factor beta receptor activity, type II Added SYNONYM type II TGF-beta receptor activity
2004-01-22 GO:0005026 transforming growth factor beta receptor activity, type II Added SYNONYM type II TGFbeta receptor activity
2004-01-22 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, cytoplasmic mediator activity
2004-01-22 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, cytoplasmic mediator activity
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM TGF-beta receptor binding
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM TGFbeta receptor binding
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM transforming growth factor beta
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM transforming growth factor beta receptor ligand
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Added SYNONYM TGF-beta receptor signaling pathway
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Added SYNONYM TGFbeta receptor signaling pathway
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Added SYNONYM transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0007180 obsolete transforming growth factor beta ligand binding to type II receptor Added SYNONYM TGF-beta ligand binding to type II receptor
2004-01-22 GO:0007180 obsolete transforming growth factor beta ligand binding to type II receptor Added SYNONYM TGFbeta ligand binding to type II receptor
2004-01-22 GO:0007181 transforming growth factor beta receptor complex assembly Added SYNONYM TGF-beta receptor complex assembly
2004-01-22 GO:0007181 transforming growth factor beta receptor complex assembly Added SYNONYM TGFbeta receptor complex assembly
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM TGF-alpha receptor binding
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM TGFalpha receptor binding
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM transforming growth factor alpha
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM transforming growth factor alpha receptor ligand
2004-01-22 GO:0008259 obsolete transforming growth factor beta ligand binding to type I receptor Added SYNONYM TGF-beta ligand binding to type I receptor
2004-01-22 GO:0008259 obsolete transforming growth factor beta ligand binding to type I receptor Added SYNONYM TGFbeta ligand binding to type I receptor
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM regulation of TGF-beta receptor signaling pathway
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM regulation of TGFbeta receptor signaling pathway
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM regulation of transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM positive regulation of TGF-beta receptor signaling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM positive regulation of TGFbeta receptor signaling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM positive regulation of transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM negative regulation of TGF-beta receptor signaling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM negative regulation of TGFbeta receptor signaling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM negative regulation of transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, common-partner cytoplasmic mediator activity
2004-01-22 GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, common-partner cytoplasmic mediator activity
2004-01-22 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, inhibitory cytoplasmic mediator activity
2004-01-22 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, inhibitory cytoplasmic mediator activity
2004-01-22 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, pathway-specific cytoplasmic mediator activity
2004-01-22 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, pathway-specific cytoplasmic mediator activity
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Added SYNONYM TGF-beta receptor anchoring activity
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Added SYNONYM TGFbeta receptor anchoring activity
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Added SYNONYM transforming growth factor beta receptor anchor activity
2004-01-22 GO:0050431 transforming growth factor beta binding Added SYNONYM TGF-beta binding
2004-01-22 GO:0050431 transforming growth factor beta binding Added SYNONYM TGFbeta binding
2004-01-22 GO:0050817 coagulation Added SYNONYM clotting
2004-01-22 GO:0050818 regulation of coagulation Added SYNONYM regulation of clotting
2004-01-22 GO:0050819 negative regulation of coagulation Added SYNONYM negative regulation of clotting.
2004-01-22 GO:0050820 positive regulation of coagulation Added SYNONYM positive regulation of clotting
2004-01-22 GO:0050825 ice binding Added SYNONYM ice crystal binding
2004-01-22 GO:0050828 regulation of liquid surface tension Added SYNONYM regulation of surface tension of a liquid
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Deleted SYNONYM transforming growth factor-beta
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Deleted SYNONYM transforming growth factor-beta receptor ligand
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Deleted SYNONYM TGFbeta receptor signalling pathway
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Deleted SYNONYM transforming growth factor-alpha
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Deleted SYNONYM transforming growth factor-alpha receptor ligand
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Deleted SYNONYM regulation of TGFbeta receptor signalling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Deleted SYNONYM positive regulation of TGFbeta receptor signalling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Deleted SYNONYM negative regulation of TGFbeta receptor signalling pathway
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Deleted SYNONYM transforming growth factor-beta receptor anchor activity
2004-01-22 GO:0050431 transforming growth factor beta binding Deleted SYNONYM transforming growth factor beta binding
2004-01-22 GO:0005024 transforming growth factor beta-activated receptor activity Added SYNONYM TGFbeta receptor activity
2004-01-22 GO:0005025 transforming growth factor beta receptor activity, type I Added SYNONYM type I TGF-beta receptor activity
2004-01-22 GO:0005025 transforming growth factor beta receptor activity, type I Added SYNONYM type I TGFbeta receptor activity
2004-01-22 GO:0050820 positive regulation of coagulation Added DEFINITION Any process that activates or increases the rate of coagulation.
2004-01-22 GO:0017149 obsolete protein biosynthetic process inhibitor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-01-22 GO:0000211 obsolete protein degradation tagging activity Updated DEFINITION OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction.
2004-01-22 GO:0050821 protein stabilization Added DEFINITION The processes involved in maintaining the structure and integrity of a protein and preventing it from being degraded.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2004-01-22 GO:0005026 transforming growth factor beta receptor activity, type II Updated TERM type II transforming growth factor beta receptor activity
2004-01-22 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, cytoplasmic mediator activity
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Updated TERM transforming growth factor beta receptor binding
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Updated TERM positive regulation of transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Updated TERM negative regulation of transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Updated TERM regulation of transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0043065 positive regulation of apoptotic process Updated TERM positive regulation of apoptosis
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Updated TERM transforming growth factor beta receptor anchoring activity
2004-01-22 GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
2004-01-22 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
2004-01-22 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Updated TERM transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
2004-01-22 GO:0050815 phosphoserine residue binding Added TERM phosphoserine binding
2004-01-22 GO:0050816 phosphothreonine residue binding Added TERM phosphothreonine binding
2004-01-22 GO:0050817 coagulation Added TERM coagulation
2004-01-22 GO:0050818 regulation of coagulation Added TERM regulation of coagulation
2004-01-22 GO:0050819 negative regulation of coagulation Added TERM negative regulation of coagulation
2004-01-22 GO:0050820 positive regulation of coagulation Added TERM positive regulation of coagulation
2004-01-22 GO:0050821 protein stabilization Added TERM protein stabilization
2004-01-22 GO:0050822 peptide stabilization Added TERM peptide stabilization
2004-01-22 GO:0050823 peptide antigen stabilization Added TERM peptide antigen stabilization
2004-01-22 GO:0050824 water binding Added TERM water binding
2004-01-22 GO:0050825 ice binding Added TERM ice binding
2004-01-22 GO:0050826 response to freezing Added TERM response to freezing
2004-01-22 GO:0050827 toxin receptor binding Added TERM toxin receptor binding
2004-01-22 GO:0050828 regulation of liquid surface tension Added TERM regulation of liquid surface tension
2004-01-22 GO:0050431 transforming growth factor beta binding Updated TERM transforming growth factor beta binding
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Updated TERM transforming growth factor alpha receptor binding
2004-01-22 GO:0008259 obsolete transforming growth factor beta ligand binding to type I receptor Updated TERM transforming growth factor beta ligand binding to type I receptor
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Updated TERM transforming growth factor beta receptor signaling pathway
2004-01-22 GO:0007180 obsolete transforming growth factor beta ligand binding to type II receptor Updated TERM transforming growth factor beta ligand binding to type II receptor
2004-01-22 GO:0007181 transforming growth factor beta receptor complex assembly Updated TERM transforming growth factor beta receptor complex assembly
2004-01-22 GO:0005024 transforming growth factor beta-activated receptor activity Updated TERM transforming growth factor beta receptor activity
2004-01-22 GO:0005025 transforming growth factor beta receptor activity, type I Updated TERM type I transforming growth factor beta receptor activity

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-01-22 GO:0017028 obsolete protein stabilization activity Updated DEFINITION OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds.
2004-01-22 GO:0008638 obsolete protein tagging activity Updated DEFINITION OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e. g. degradation.
2004-01-22 GO:0050818 regulation of coagulation Added DEFINITION Any process that modulates the frequency, rate or extent of coagulation, the process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
2004-01-22 GO:0050828 regulation of liquid surface tension Added DEFINITION Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.
2004-01-22 GO:0050826 response to freezing Added DEFINITION A change in state or activity of an organism (in terms of movement, secretion, gene expression, enzyme production, etc.) in response to temperatures below 0 degrees Celsius.
2004-01-22 GO:0019214 obsolete surfactant activity Updated DEFINITION OBSOLETE. The action of reducing the surface tension of a liquid.
2004-01-22 GO:0015070 obsolete toxin activity Updated DEFINITION OBSOLETE. Acts as to cause injury to other living organisms.
2004-01-22 GO:0050827 toxin receptor binding Added DEFINITION Interacting selectively with a toxin receptor, a receptor for substances that cause injury to living organisms.
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Updated DEFINITION Interacting selectively with the transforming growth factor alpha receptor.
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Updated DEFINITION Interacting selectively with the transforming growth factor beta receptor.
2004-01-22 GO:0050824 water binding Added DEFINITION Interacting selectively with water (H2O).
2004-01-22 GO:0016172 obsolete antifreeze activity Updated DEFINITION OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (eg. blood) at below freezing exogenous temperatures.
2004-01-22 GO:0003800 obsolete antiviral response protein activity Added DEFINITION OBSOLETE. A protein involved in an antiviral response.
2004-01-22 GO:0016506 obsolete apoptosis activator activity Updated DEFINITION OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.
2004-01-22 GO:0008189 obsolete apoptosis inhibitor activity Updated DEFINITION OBSOLETE. The function held by products which directly block any step in the process of apoptosis.
2004-01-22 GO:0016329 obsolete apoptosis regulator activity Updated DEFINITION OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.
2004-01-22 GO:0017030 obsolete beta-galactosidase stabilization activity Added DEFINITION OBSOLETE. Stabilization of the structure of beta-galactosidase.
2004-01-22 GO:0003801 obsolete blood coagulation factor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-01-22 GO:0042280 obsolete cell surface antigen activity, host-interacting Updated DEFINITION OBSOLETE. Functions as an immunogenic target for the host immune system that masks other invariant surface molecules from immune recognition.
2004-01-22 GO:0050817 coagulation Added DEFINITION The process by which a fluid solution, or part of it, changes into a solid or semisolid mass.
2004-01-22 GO:0003811 obsolete complement activity Updated DEFINITION OBSOLETE. Any of a set of activities involved in the complement cascade.
2004-01-22 GO:0030009 obsolete complement factor H activity Updated DEFINITION OBSOLETE. A cofactor for the serine protease complement factor I.
2004-01-22 GO:0003793 obsolete defense/immunity protein activity Updated DEFINITION OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease.
2004-01-22 GO:0008025 obsolete diazepam binding inhibitor activity Updated DEFINITION OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters.
2004-01-22 GO:0050825 ice binding Added DEFINITION Interacting selectively with ice, water reduced to the solid state by cold temperature. It is a white or transparent colourless substance, crystalline, brittle, and viscoidal.
2004-01-22 GO:0019833 obsolete ice nucleation activity Updated DEFINITION OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation (see GO:0019833).
2004-01-22 GO:0016173 obsolete ice nucleation inhibitor activity Updated DEFINITION OBSOLETE. Inhibits the the formation of ice crystals.
2004-01-22 GO:0050819 negative regulation of coagulation Added DEFINITION Any process that stops, prevents or reduces the rate of coagulation.
2004-01-22 GO:0050823 peptide antigen stabilization Added DEFINITION The processes involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.
2004-01-22 GO:0048192 obsolete peptide antigen stabilization activity Updated DEFINITION OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell.
2004-01-22 GO:0050822 peptide stabilization Added DEFINITION The processes involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.
2004-01-22 GO:0048191 obsolete peptide stabilization activity Updated DEFINITION OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
2004-01-22 GO:0050815 phosphoserine residue binding Added DEFINITION Interacting selectively with a phosphorylated serine residue within a protein.
2004-01-22 GO:0045310 obsolete phosphoserine/phosphothreonine binding Updated DEFINITION OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein.
2004-01-22 GO:0050816 phosphothreonine residue binding Added DEFINITION Interacting selectively with a phosphorylated threonine residue within a protein.
2004-01-22 GO:0003794 obsolete acute-phase response protein activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-01-22 GO:0008435 obsolete anticoagulant activity Updated DEFINITION OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation.
2004-01-22 GO:0005026 transforming growth factor beta receptor activity, type II Added SYNONYM type II TGF-beta receptor activity
2004-01-22 GO:0005026 transforming growth factor beta receptor activity, type II Added SYNONYM type II TGFbeta receptor activity
2004-01-22 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, cytoplasmic mediator activity
2004-01-22 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, cytoplasmic mediator activity
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM TGF-beta receptor binding
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM TGFbeta receptor binding
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM transforming growth factor beta
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Added SYNONYM transforming growth factor beta receptor ligand
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Added SYNONYM TGF-beta receptor signaling pathway
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Added SYNONYM TGFbeta receptor signaling pathway
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Added SYNONYM transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0007180 obsolete transforming growth factor beta ligand binding to type II receptor Added SYNONYM TGF-beta ligand binding to type II receptor
2004-01-22 GO:0007180 obsolete transforming growth factor beta ligand binding to type II receptor Added SYNONYM TGFbeta ligand binding to type II receptor
2004-01-22 GO:0007181 transforming growth factor beta receptor complex assembly Added SYNONYM TGF-beta receptor complex assembly
2004-01-22 GO:0007181 transforming growth factor beta receptor complex assembly Added SYNONYM TGFbeta receptor complex assembly
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM TGF-alpha receptor binding
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM TGFalpha receptor binding
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM transforming growth factor alpha
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Added SYNONYM transforming growth factor alpha receptor ligand
2004-01-22 GO:0008259 obsolete transforming growth factor beta ligand binding to type I receptor Added SYNONYM TGF-beta ligand binding to type I receptor
2004-01-22 GO:0008259 obsolete transforming growth factor beta ligand binding to type I receptor Added SYNONYM TGFbeta ligand binding to type I receptor
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM regulation of TGF-beta receptor signaling pathway
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM regulation of TGFbeta receptor signaling pathway
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM regulation of transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM positive regulation of TGF-beta receptor signaling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM positive regulation of TGFbeta receptor signaling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM positive regulation of transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM negative regulation of TGF-beta receptor signaling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM negative regulation of TGFbeta receptor signaling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Added SYNONYM negative regulation of transforming growth factor beta receptor signalling pathway
2004-01-22 GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, common-partner cytoplasmic mediator activity
2004-01-22 GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, common-partner cytoplasmic mediator activity
2004-01-22 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, inhibitory cytoplasmic mediator activity
2004-01-22 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, inhibitory cytoplasmic mediator activity
2004-01-22 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Added SYNONYM TGF-beta receptor, pathway-specific cytoplasmic mediator activity
2004-01-22 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Added SYNONYM TGFbeta receptor, pathway-specific cytoplasmic mediator activity
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Added SYNONYM TGF-beta receptor anchoring activity
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Added SYNONYM TGFbeta receptor anchoring activity
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Added SYNONYM transforming growth factor beta receptor anchor activity
2004-01-22 GO:0050431 transforming growth factor beta binding Added SYNONYM TGF-beta binding
2004-01-22 GO:0050431 transforming growth factor beta binding Added SYNONYM TGFbeta binding
2004-01-22 GO:0050817 coagulation Added SYNONYM clotting
2004-01-22 GO:0050818 regulation of coagulation Added SYNONYM regulation of clotting
2004-01-22 GO:0050819 negative regulation of coagulation Added SYNONYM negative regulation of clotting.
2004-01-22 GO:0050820 positive regulation of coagulation Added SYNONYM positive regulation of clotting
2004-01-22 GO:0050825 ice binding Added SYNONYM ice crystal binding
2004-01-22 GO:0050828 regulation of liquid surface tension Added SYNONYM regulation of surface tension of a liquid
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Deleted SYNONYM transforming growth factor-beta
2004-01-22 GO:0005160 transforming growth factor beta receptor binding Deleted SYNONYM transforming growth factor-beta receptor ligand
2004-01-22 GO:0007179 transforming growth factor beta receptor signaling pathway Deleted SYNONYM TGFbeta receptor signalling pathway
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Deleted SYNONYM transforming growth factor-alpha
2004-01-22 GO:0008185 transforming growth factor alpha receptor binding Deleted SYNONYM transforming growth factor-alpha receptor ligand
2004-01-22 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway Deleted SYNONYM regulation of TGFbeta receptor signalling pathway
2004-01-22 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway Deleted SYNONYM positive regulation of TGFbeta receptor signalling pathway
2004-01-22 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Deleted SYNONYM negative regulation of TGFbeta receptor signalling pathway
2004-01-22 GO:0042057 obsolete transforming growth factor beta receptor anchoring activity Deleted SYNONYM transforming growth factor-beta receptor anchor activity
2004-01-22 GO:0050431 transforming growth factor beta binding Deleted SYNONYM transforming growth factor beta binding
2004-01-22 GO:0005024 transforming growth factor beta-activated receptor activity Added SYNONYM TGFbeta receptor activity
2004-01-22 GO:0005025 transforming growth factor beta receptor activity, type I Added SYNONYM type I TGF-beta receptor activity
2004-01-22 GO:0005025 transforming growth factor beta receptor activity, type I Added SYNONYM type I TGFbeta receptor activity
2004-01-22 GO:0050820 positive regulation of coagulation Added DEFINITION Any process that activates or increases the rate of coagulation.
2004-01-22 GO:0017149 obsolete protein biosynthetic process inhibitor activity Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2004-01-22 GO:0000211 obsolete protein degradation tagging activity Updated DEFINITION OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction.
2004-01-22 GO:0050821 protein stabilization Added DEFINITION The processes involved in maintaining the structure and integrity of a protein and preventing it from being degraded.
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