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GO Term History: Displaying 64 audit records for all terms for the date 2004-01-10

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2004-01-10 GO:0045202 synapse Added SYNONYM synaptic junction
2004-01-10 GO:0045884 regulation of survival gene product expression Added SYNONYM regulation of survival gene products
2004-01-10 GO:0045885 positive regulation of survival gene product expression Added SYNONYM positive regulation of survival gene products
2004-01-10 GO:0047485 protein N-terminus binding Added SYNONYM N-terminal binding
2004-01-10 GO:0019050 suppression by virus of host apoptotic process Deleted SYNONYM negative regulation by virus of apoptosis
2004-01-10 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Deleted SYNONYM cystic fibrosis transmembrane conductance regulator binding
2004-01-10 GO:0045202 synapse Deleted SYNONYM synapse
2004-01-10 GO:0004523 RNA-DNA hybrid ribonuclease activity Added SYNONYM calf thymus ribonuclease H activity
2004-01-10 GO:0005520 insulin-like growth factor binding Added SYNONYM IGF binding
2004-01-10 GO:0007416 synapse assembly Added SYNONYM synapse biogenesis
2004-01-10 GO:0008022 protein C-terminus binding Added SYNONYM C-terminal binding
2004-01-10 GO:0008139 nuclear localization sequence binding Added SYNONYM nuclear localization signal binding
2004-01-10 GO:0008190 eukaryotic initiation factor 4E binding Added SYNONYM eIF4E binding
2004-01-10 GO:0008634 negative regulation of survival gene product expression Added SYNONYM negative regulation of survival gene products
2004-01-10 GO:0016917 GABA receptor activity Added SYNONYM GABA binding
2004-01-10 GO:0016917 GABA receptor activity Added SYNONYM gamma aminobutyrate binding
2004-01-10 GO:0016917 GABA receptor activity Added SYNONYM gamma aminobutyric acid binding
2004-01-10 GO:0019050 suppression by virus of host apoptotic process Added SYNONYM negative regulation of apoptosis by virus
2004-01-10 GO:0004523 RNA-DNA hybrid ribonuclease activity Updated TERM ribonuclease H activity
2004-01-10 GO:0001507 acetylcholine catabolic process in synaptic cleft Updated TERM acetylcholine breakdown in synaptic cleft
2004-01-10 GO:0008634 negative regulation of survival gene product expression Updated TERM negative regulation of survival gene product activity
2004-01-10 GO:0030897 HOPS complex Added TERM HOPS complex
2004-01-10 GO:0030306 ADP-ribosylation factor binding Updated TERM ADP-ribosylation factor binding
2004-01-10 GO:0045885 positive regulation of survival gene product expression Updated TERM positive regulation of survival gene product activity
2004-01-10 GO:0045202 synapse Updated TERM synapse
2004-01-10 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Updated TERM cystic fibrosis transmembrane conductance regulator binding
2004-01-10 GO:0050803 regulation of synapse structure or activity Added TERM regulation of synapse structure and function
2004-01-10 GO:0050804 regulation of synaptic transmission Added TERM regulation of synaptic transmission
2004-01-10 GO:0050805 negative regulation of synaptic transmission Added TERM negative regulation of synaptic transmission
2004-01-10 GO:0050806 positive regulation of synaptic transmission Added TERM positive regulation of synaptic transmission
2004-01-10 GO:0050807 regulation of synapse organization Added TERM regulation of synapse structure
2004-01-10 GO:0050808 synapse organization Added TERM synapse organization and biogenesis
2004-01-10 GO:0045884 regulation of survival gene product expression Updated TERM regulation of survival gene product activity
2004-01-10 GO:0030306 ADP-ribosylation factor binding Added DEFINITION Interacting selectively with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells.
2004-01-10 GO:0009940 amino-terminal vacuolar sorting propeptide binding Updated DEFINITION Interacting selectively with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin coated vesicles.
2004-01-10 GO:0019957 C-C chemokine binding Added DEFINITION Interacting selectively with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
2004-01-10 GO:0019958 C-X-C chemokine binding Added DEFINITION Interacting selectively with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.
2004-01-10 GO:0019960 C-X3-C chemokine binding Added DEFINITION Interacting selectively with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.
2004-01-10 GO:0005518 collagen binding Updated DEFINITION Interacting selectively with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2004-01-10 GO:0017033 DNA topoisomerase I binding Added DEFINITION Interacting selectively with the enzyme DNA topoisomerase I.
2004-01-10 GO:0008190 eukaryotic initiation factor 4E binding Added DEFINITION Interacting selectively with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.
2004-01-10 GO:0030742 GTP-dependent protein binding Added DEFINITION Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP.
2004-01-10 GO:0030897 HOPS complex Added DEFINITION A multimeric protein complex that associates with the vacuolar membrane and is involved in homotypic vacuole fusion and vacuole protein sorting. For example, the Saccharomyces complex contains Vps41p, Vam6p, Pep5p, Vps16p, Pep3p, and Vps33p.
2004-01-10 GO:0030544 Hsp70 protein binding Added DEFINITION Interacting selectively with Hsp70 proteins, any of a group of heat-shock proteins around 70kDa in size.
2004-01-10 GO:0005520 insulin-like growth factor binding Added DEFINITION Interacting selectively with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.
2004-01-10 GO:0019215 intermediate filament binding Added DEFINITION Interacting selectively with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.
2004-01-10 GO:0016030 metarhodopsin binding Added DEFINITION Interacting selectively with metarhodopsin, a transient intermediate produced upon irradiation of rhodopsin in the visual cycle and existing in two forms, metarhodopsins I and II. The latter dissociates to form opsin and all-trans retinal.
2004-01-10 GO:0050805 negative regulation of synaptic transmission Added DEFINITION Any process that stops, prevents or reduces the rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2004-01-10 GO:0008139 nuclear localization sequence binding Added DEFINITION Interacting selectively with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus.
2004-01-10 GO:0005051 peroxisome targeting signal receptor activity Added DEFINITION Combining with a peroxisome targeting signal to initiate a change in cell activity.
2004-01-10 GO:0050806 positive regulation of synaptic transmission Added DEFINITION Any process that activates or increases the rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2004-01-10 GO:0005522 profilin binding Added DEFINITION Interacting selectively with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.
2004-01-10 GO:0008022 protein C-terminus binding Added DEFINITION Interacting selectively with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2004-01-10 GO:0047485 protein N-terminus binding Updated DEFINITION Interacting selectively with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2004-01-10 GO:0007273 regulation of synapse Added DEFINITION OBSOLETE (this term was not defined before being made obsolete).
2004-01-10 GO:0050807 regulation of synapse organization Added DEFINITION Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-01-10 GO:0050803 regulation of synapse structure or activity Added DEFINITION Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-01-10 GO:0050804 regulation of synaptic transmission Added DEFINITION Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2004-01-10 GO:0050808 synapse organization Added DEFINITION The assembly and organization of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-01-10 GO:0005523 tropomyosin binding Added DEFINITION Interacting selectively with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.
2004-01-10 GO:0017166 vinculin binding Added DEFINITION Interacting selectively with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.
2004-01-10 GO:0030306 ADP-ribosylation factor binding Added SYNONYM ARF binding
2004-01-10 GO:0042654 ecdysis-triggering hormone receptor activity Added SYNONYM ecdysis-triggering hormone binding
2004-01-10 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Added SYNONYM CFTR binding

Terms

Timestamp GO ID GO Term Name Action Category Detail
2004-01-10 GO:0004523 RNA-DNA hybrid ribonuclease activity Updated TERM ribonuclease H activity
2004-01-10 GO:0001507 acetylcholine catabolic process in synaptic cleft Updated TERM acetylcholine breakdown in synaptic cleft
2004-01-10 GO:0008634 negative regulation of survival gene product expression Updated TERM negative regulation of survival gene product activity
2004-01-10 GO:0030897 HOPS complex Added TERM HOPS complex
2004-01-10 GO:0030306 ADP-ribosylation factor binding Updated TERM ADP-ribosylation factor binding
2004-01-10 GO:0045885 positive regulation of survival gene product expression Updated TERM positive regulation of survival gene product activity
2004-01-10 GO:0045202 synapse Updated TERM synapse
2004-01-10 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Updated TERM cystic fibrosis transmembrane conductance regulator binding
2004-01-10 GO:0050803 regulation of synapse structure or activity Added TERM regulation of synapse structure and function
2004-01-10 GO:0050804 regulation of synaptic transmission Added TERM regulation of synaptic transmission
2004-01-10 GO:0050805 negative regulation of synaptic transmission Added TERM negative regulation of synaptic transmission
2004-01-10 GO:0050806 positive regulation of synaptic transmission Added TERM positive regulation of synaptic transmission
2004-01-10 GO:0050807 regulation of synapse organization Added TERM regulation of synapse structure
2004-01-10 GO:0050808 synapse organization Added TERM synapse organization and biogenesis
2004-01-10 GO:0045884 regulation of survival gene product expression Updated TERM regulation of survival gene product activity

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2004-01-10 GO:0045202 synapse Added SYNONYM synaptic junction
2004-01-10 GO:0045884 regulation of survival gene product expression Added SYNONYM regulation of survival gene products
2004-01-10 GO:0045885 positive regulation of survival gene product expression Added SYNONYM positive regulation of survival gene products
2004-01-10 GO:0047485 protein N-terminus binding Added SYNONYM N-terminal binding
2004-01-10 GO:0019050 suppression by virus of host apoptotic process Deleted SYNONYM negative regulation by virus of apoptosis
2004-01-10 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Deleted SYNONYM cystic fibrosis transmembrane conductance regulator binding
2004-01-10 GO:0045202 synapse Deleted SYNONYM synapse
2004-01-10 GO:0004523 RNA-DNA hybrid ribonuclease activity Added SYNONYM calf thymus ribonuclease H activity
2004-01-10 GO:0005520 insulin-like growth factor binding Added SYNONYM IGF binding
2004-01-10 GO:0007416 synapse assembly Added SYNONYM synapse biogenesis
2004-01-10 GO:0008022 protein C-terminus binding Added SYNONYM C-terminal binding
2004-01-10 GO:0008139 nuclear localization sequence binding Added SYNONYM nuclear localization signal binding
2004-01-10 GO:0008190 eukaryotic initiation factor 4E binding Added SYNONYM eIF4E binding
2004-01-10 GO:0008634 negative regulation of survival gene product expression Added SYNONYM negative regulation of survival gene products
2004-01-10 GO:0016917 GABA receptor activity Added SYNONYM GABA binding
2004-01-10 GO:0016917 GABA receptor activity Added SYNONYM gamma aminobutyrate binding
2004-01-10 GO:0016917 GABA receptor activity Added SYNONYM gamma aminobutyric acid binding
2004-01-10 GO:0019050 suppression by virus of host apoptotic process Added SYNONYM negative regulation of apoptosis by virus
2004-01-10 GO:0030306 ADP-ribosylation factor binding Added DEFINITION Interacting selectively with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells.
2004-01-10 GO:0009940 amino-terminal vacuolar sorting propeptide binding Updated DEFINITION Interacting selectively with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin coated vesicles.
2004-01-10 GO:0019957 C-C chemokine binding Added DEFINITION Interacting selectively with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
2004-01-10 GO:0019958 C-X-C chemokine binding Added DEFINITION Interacting selectively with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.
2004-01-10 GO:0019960 C-X3-C chemokine binding Added DEFINITION Interacting selectively with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.
2004-01-10 GO:0005518 collagen binding Updated DEFINITION Interacting selectively with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2004-01-10 GO:0017033 DNA topoisomerase I binding Added DEFINITION Interacting selectively with the enzyme DNA topoisomerase I.
2004-01-10 GO:0008190 eukaryotic initiation factor 4E binding Added DEFINITION Interacting selectively with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.
2004-01-10 GO:0030742 GTP-dependent protein binding Added DEFINITION Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP.
2004-01-10 GO:0030897 HOPS complex Added DEFINITION A multimeric protein complex that associates with the vacuolar membrane and is involved in homotypic vacuole fusion and vacuole protein sorting. For example, the Saccharomyces complex contains Vps41p, Vam6p, Pep5p, Vps16p, Pep3p, and Vps33p.
2004-01-10 GO:0030544 Hsp70 protein binding Added DEFINITION Interacting selectively with Hsp70 proteins, any of a group of heat-shock proteins around 70kDa in size.
2004-01-10 GO:0005520 insulin-like growth factor binding Added DEFINITION Interacting selectively with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.
2004-01-10 GO:0019215 intermediate filament binding Added DEFINITION Interacting selectively with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.
2004-01-10 GO:0016030 metarhodopsin binding Added DEFINITION Interacting selectively with metarhodopsin, a transient intermediate produced upon irradiation of rhodopsin in the visual cycle and existing in two forms, metarhodopsins I and II. The latter dissociates to form opsin and all-trans retinal.
2004-01-10 GO:0050805 negative regulation of synaptic transmission Added DEFINITION Any process that stops, prevents or reduces the rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2004-01-10 GO:0008139 nuclear localization sequence binding Added DEFINITION Interacting selectively with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus.
2004-01-10 GO:0005051 peroxisome targeting signal receptor activity Added DEFINITION Combining with a peroxisome targeting signal to initiate a change in cell activity.
2004-01-10 GO:0050806 positive regulation of synaptic transmission Added DEFINITION Any process that activates or increases the rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2004-01-10 GO:0005522 profilin binding Added DEFINITION Interacting selectively with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.
2004-01-10 GO:0008022 protein C-terminus binding Added DEFINITION Interacting selectively with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2004-01-10 GO:0047485 protein N-terminus binding Updated DEFINITION Interacting selectively with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2004-01-10 GO:0007273 regulation of synapse Added DEFINITION OBSOLETE (this term was not defined before being made obsolete).
2004-01-10 GO:0050807 regulation of synapse organization Added DEFINITION Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-01-10 GO:0050803 regulation of synapse structure or activity Added DEFINITION Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-01-10 GO:0050804 regulation of synaptic transmission Added DEFINITION Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
2004-01-10 GO:0050808 synapse organization Added DEFINITION The assembly and organization of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2004-01-10 GO:0005523 tropomyosin binding Added DEFINITION Interacting selectively with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.
2004-01-10 GO:0017166 vinculin binding Added DEFINITION Interacting selectively with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.
2004-01-10 GO:0030306 ADP-ribosylation factor binding Added SYNONYM ARF binding
2004-01-10 GO:0042654 ecdysis-triggering hormone receptor activity Added SYNONYM ecdysis-triggering hormone binding
2004-01-10 GO:0042980 cystic fibrosis transmembrane conductance regulator binding Added SYNONYM CFTR binding
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