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GO Term History: Displaying 31 audit records for all terms for the date 2003-11-11

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2003-11-11 GO:0001767 establishment of lymphocyte polarity Added DEFINITION The directed orientation of lymphocyte signaling molecules and associated lipid rafts towards a chemokine gradient or a contact point with an appropriate activating cell.
2003-11-11 GO:0001769 establishment of B cell polarity Added DEFINITION The directed orientation of B-cell signaling molecules and associated lipid rafts towards a chemokine gradient of a contact point with an antigen displaying cell.
2003-11-11 GO:0001768 establishment of T cell polarity Added DEFINITION The directed orientation of T-cell signaling molecules and associated lipid rafts towards a chemokine gradient or a contact point with antigen presenting cell.
2003-11-11 GO:0001771 immunological synapse formation Added DEFINITION The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated lipid rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-recpetor interaction.
2003-11-11 GO:0001772 immunological synapse Added DEFINITION An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated lipid rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
2003-11-11 GO:0046649 lymphocyte activation Updated DEFINITION A change in morphology and behavior of of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
2003-11-11 GO:0030098 lymphocyte differentiation Updated DEFINITION The process whereby a relatively unspecialized precursor cell acquires specialized features of B, T-cells, or natural killer cells.
2003-11-11 GO:0042116 macrophage activation Updated DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0045576 mast cell activation Updated DEFINITION The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
2003-11-11 GO:0001774 microglial cell activation Added DEFINITION The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0042117 monocyte activation Updated DEFINITION The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0030101 natural killer cell activation Updated DEFINITION The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0042119 neutrophil activation Added DEFINITION The change in morphology and behavior of a neutrophil resulting from exposure to cytokines, chemokines, pathogens, or soluble factors.
2003-11-11 GO:0035059 RCAF complex Added DEFINITION A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.
2003-11-11 GO:0042110 T cell activation Updated DEFINITION The change in morphology and behavior of a mature or immature T-cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2003-11-11 GO:0048143 astrocyte activation Updated DEFINITION A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2003-11-11 GO:0042113 B cell activation Updated DEFINITION The change in morphology and behavior of a mature or immature B-cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2003-11-11 GO:0045575 basophil activation Updated DEFINITION The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE cound to Fc-epsilonRI receptors.
2003-11-11 GO:0001773 myeloid dendritic cell activation Added DEFINITION The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, pathogens, or soluble factor.
2003-11-11 GO:0042118 endothelial cell activation Added DEFINITION The change in morphology and behavior of an endothelial cell resulting from epxosure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0035059 RCAF complex Added TERM RCAF complex
2003-11-11 GO:0001768 establishment of T cell polarity Added TERM establishment of T-cell polarity
2003-11-11 GO:0001769 establishment of B cell polarity Added TERM establishment of B-cell polarity
2003-11-11 GO:0001770 establishment of natural killer cell polarity Added TERM estabilishment of natural killer cell polarity
2003-11-11 GO:0001771 immunological synapse formation Added TERM formation of immunological synapse
2003-11-11 GO:0001772 immunological synapse Added TERM immunological synapse
2003-11-11 GO:0001773 myeloid dendritic cell activation Added TERM dendritic cell activation
2003-11-11 GO:0001774 microglial cell activation Added TERM microglial cell activation
2003-11-11 GO:0001767 establishment of lymphocyte polarity Added TERM estabilshment of lymphocyte polarity
2003-11-11 GO:0035059 RCAF complex Added SYNONYM replication-coupling assembly factor complex
2003-11-11 GO:0001770 establishment of natural killer cell polarity Added DEFINITION The directed orientation of natural killer cell signaling molecules and associated lipid rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2003-11-11 GO:0035059 RCAF complex Added TERM RCAF complex
2003-11-11 GO:0001768 establishment of T cell polarity Added TERM establishment of T-cell polarity
2003-11-11 GO:0001769 establishment of B cell polarity Added TERM establishment of B-cell polarity
2003-11-11 GO:0001770 establishment of natural killer cell polarity Added TERM estabilishment of natural killer cell polarity
2003-11-11 GO:0001771 immunological synapse formation Added TERM formation of immunological synapse
2003-11-11 GO:0001772 immunological synapse Added TERM immunological synapse
2003-11-11 GO:0001773 myeloid dendritic cell activation Added TERM dendritic cell activation
2003-11-11 GO:0001774 microglial cell activation Added TERM microglial cell activation
2003-11-11 GO:0001767 establishment of lymphocyte polarity Added TERM estabilshment of lymphocyte polarity

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2003-11-11 GO:0001767 establishment of lymphocyte polarity Added DEFINITION The directed orientation of lymphocyte signaling molecules and associated lipid rafts towards a chemokine gradient or a contact point with an appropriate activating cell.
2003-11-11 GO:0001769 establishment of B cell polarity Added DEFINITION The directed orientation of B-cell signaling molecules and associated lipid rafts towards a chemokine gradient of a contact point with an antigen displaying cell.
2003-11-11 GO:0001768 establishment of T cell polarity Added DEFINITION The directed orientation of T-cell signaling molecules and associated lipid rafts towards a chemokine gradient or a contact point with antigen presenting cell.
2003-11-11 GO:0001771 immunological synapse formation Added DEFINITION The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated lipid rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-recpetor interaction.
2003-11-11 GO:0001772 immunological synapse Added DEFINITION An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated lipid rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
2003-11-11 GO:0046649 lymphocyte activation Updated DEFINITION A change in morphology and behavior of of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
2003-11-11 GO:0030098 lymphocyte differentiation Updated DEFINITION The process whereby a relatively unspecialized precursor cell acquires specialized features of B, T-cells, or natural killer cells.
2003-11-11 GO:0042116 macrophage activation Updated DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0045576 mast cell activation Updated DEFINITION The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
2003-11-11 GO:0001774 microglial cell activation Added DEFINITION The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0042117 monocyte activation Updated DEFINITION The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0030101 natural killer cell activation Updated DEFINITION The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0042119 neutrophil activation Added DEFINITION The change in morphology and behavior of a neutrophil resulting from exposure to cytokines, chemokines, pathogens, or soluble factors.
2003-11-11 GO:0035059 RCAF complex Added DEFINITION A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.
2003-11-11 GO:0042110 T cell activation Updated DEFINITION The change in morphology and behavior of a mature or immature T-cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2003-11-11 GO:0048143 astrocyte activation Updated DEFINITION A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
2003-11-11 GO:0042113 B cell activation Updated DEFINITION The change in morphology and behavior of a mature or immature B-cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2003-11-11 GO:0045575 basophil activation Updated DEFINITION The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE cound to Fc-epsilonRI receptors.
2003-11-11 GO:0001773 myeloid dendritic cell activation Added DEFINITION The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, pathogens, or soluble factor.
2003-11-11 GO:0042118 endothelial cell activation Added DEFINITION The change in morphology and behavior of an endothelial cell resulting from epxosure to a cytokine, chemokine, cellular ligand, pathogen, or soluble factor.
2003-11-11 GO:0035059 RCAF complex Added SYNONYM replication-coupling assembly factor complex
2003-11-11 GO:0001770 establishment of natural killer cell polarity Added DEFINITION The directed orientation of natural killer cell signaling molecules and associated lipid rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.
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