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GO Term History: Displaying 124 audit records for all terms for the date 2003-10-22

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2003-10-22 GO:0050726 positive regulation of interleukin-1 alpha biosynthetic process Added DEFINITION Any process that activates or increases the rate of the formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050717 positive regulation of interleukin-1 alpha secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050725 positive regulation of interleukin-1 beta biosynthetic process Added DEFINITION Any process that activates or increases the rate of the formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050718 positive regulation of interleukin-1 beta secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of interleukin-1 beta from a cell or group of cells.
2003-10-22 GO:0050716 positive regulation of interleukin-1 secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of interleukin-1 from a cell or group of cells.
2003-10-22 GO:0035057 positive regulation of nuclear mRNA splicing via U2-type spliceosome Added DEFINITION Any process that activates or increases the rate or extent of mRNA splicing via a U2-type spliceosome.
2003-10-22 GO:0050714 positive regulation of protein secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of a protein from a cell or group of cells.
2003-10-22 GO:0001526 proteoglycan sulfate transfer Updated DEFINITION OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate.
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate (PAPS) + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.
2003-10-22 GO:0007511 dorsal vessel development Deleted TERM dorsal vessel development
2003-10-22 GO:0007513 pericardial cell differentiation Updated TERM pericardial cell differentiation
2003-10-22 GO:0006924 activation-induced cell death of T cells Updated TERM programmed cell death, activated T-cells
2003-10-22 GO:0006925 inflammatory cell apoptotic process Updated TERM programmed cell death, inflammatory cells
2003-10-22 GO:0006926 virus-infected cell apoptotic process Updated TERM programmed cell death, virus-infected cells
2003-10-22 GO:0006927 transformed cell apoptotic process Updated TERM programmed cell death, transformed cells
2003-10-22 GO:0035050 embryonic heart tube development Added TERM embryonic heart tube development
2003-10-22 GO:0035051 cardiocyte differentiation Added TERM cardiac cell differentiation
2003-10-22 GO:0035052 dorsal vessel aortic cell fate commitment Added TERM aortic cell fate commitment (sensu Drosophila)
2003-10-22 GO:0035053 dorsal vessel heart proper cell fate commitment Added TERM heart proper cell fate commitment (sensu Drosophila)
2003-10-22 GO:0035054 embryonic heart tube anterior/posterior pattern specification Added TERM embryonic heart tube anterior/posterior pattern formation
2003-10-22 GO:0035055 regulation of nuclear mRNA splicing via U2-type spliceosome Added TERM regulation of nuclear mRNA splicing via U2-type spliceosome
2003-10-22 GO:0035056 negative regulation of nuclear mRNA splicing via U2-type spliceosome Added TERM negative regulation of nuclear mRNA splicing via U2-type spliceosome
2003-10-22 GO:0035057 positive regulation of nuclear mRNA splicing via U2-type spliceosome Added TERM positive regulation of nuclear mRNA splicing via U2-type spliceosome
2003-10-22 GO:0043009 chordate embryonic development Added TERM embryonic development (sensu Vertebrata)
2003-10-22 GO:0043010 camera-type eye development Added TERM eye morphogenesis (sensu Vertebrata)
2003-10-22 GO:0043011 myeloid dendritic cell differentiation Added TERM dendritic cell differentiation
2003-10-22 GO:0043012 regulation of fusion of sperm to egg plasma membrane Added TERM regulation of fusion of sperm to egg plasma membrane
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added TERM negative regulation of fusion of sperm to egg plasma membrane
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added TERM proteoglycan sulfotransferase activity
2003-10-22 GO:0050699 WW domain binding Added TERM WW domain binding
2003-10-22 GO:0050700 CARD domain binding Added TERM CARD domain binding
2003-10-22 GO:0050701 interleukin-1 secretion Added TERM interleukin-1 secretion
2003-10-22 GO:0050702 interleukin-1 beta secretion Added TERM interleukin-1 beta secretion
2003-10-22 GO:0050703 interleukin-1 alpha secretion Added TERM interleukin-1 alpha secretion
2003-10-22 GO:0050704 regulation of interleukin-1 secretion Added TERM regulation of interleukin-1 secretion
2003-10-22 GO:0050705 regulation of interleukin-1 alpha secretion Added TERM regulation of interleukin-1 alpha secretion
2003-10-22 GO:0050706 regulation of interleukin-1 beta secretion Added TERM regulation of interleukin-1 beta secretion
2003-10-22 GO:0050707 regulation of cytokine secretion Added TERM regulation of cytokine secretion
2003-10-22 GO:0050708 regulation of protein secretion Added TERM regulation of protein secretion
2003-10-22 GO:0050709 negative regulation of protein secretion Added TERM negative regulation of protein secretion
2003-10-22 GO:0050710 negative regulation of cytokine secretion Added TERM negative regulation of cytokine secretion
2003-10-22 GO:0050711 negative regulation of interleukin-1 secretion Added TERM negative regulation of interleukin-1 secretion
2003-10-22 GO:0050712 negative regulation of interleukin-1 alpha secretion Added TERM negative regulation of interleukin-1 alpha secretion
2003-10-22 GO:0050713 negative regulation of interleukin-1 beta secretion Added TERM negative regulation of interleukin-1 beta secretion
2003-10-22 GO:0050714 positive regulation of protein secretion Added TERM positive regulation of protein secretion
2003-10-22 GO:0050715 positive regulation of cytokine secretion Added TERM positive regulation of cytokine secretion
2003-10-22 GO:0050716 positive regulation of interleukin-1 secretion Added TERM positive regulation of interleukin-1 secretion
2003-10-22 GO:0050717 positive regulation of interleukin-1 alpha secretion Added TERM positive regulation of interleukin-1 alpha secretion
2003-10-22 GO:0050718 positive regulation of interleukin-1 beta secretion Added TERM positive regulation of interleukin-1 beta secretion
2003-10-22 GO:0050719 interleukin-1 alpha biosynthetic process Added TERM interleukin-1 alpha biosynthesis
2003-10-22 GO:0050720 interleukin-1 beta biosynthetic process Added TERM interleukin-1 beta biosynthesis
2003-10-22 GO:0050721 regulation of interleukin-1 alpha biosynthetic process Added TERM regulation of interleukin-1 alpha biosynthesis
2003-10-22 GO:0050722 regulation of interleukin-1 beta biosynthetic process Added TERM regulation of interleukin-1 beta biosynthesis
2003-10-22 GO:0050723 negative regulation of interleukin-1 alpha biosynthetic process Added TERM negative regulation of interleukin-1 alpha biosynthesis
2003-10-22 GO:0050724 negative regulation of interleukin-1 beta biosynthetic process Added TERM negative regulation of interleukin-1 beta biosynthesis
2003-10-22 GO:0050725 positive regulation of interleukin-1 beta biosynthetic process Added TERM positive regulation of interleukin-1 beta biosynthesis
2003-10-22 GO:0050726 positive regulation of interleukin-1 alpha biosynthetic process Added TERM positive regulation of interleukin-1 alpha biosynthesis
2003-10-22 GO:0050727 regulation of inflammatory response Added TERM regulation of inflammatory response
2003-10-22 GO:0050728 negative regulation of inflammatory response Added TERM negative regulation of inflammatory response
2003-10-22 GO:0050729 positive regulation of inflammatory response Added TERM positive regulation of inflammatory response
2003-10-22 GO:0006924 activation-induced cell death of T cells Added SYNONYM peripheral killing of activated T-cells
2003-10-22 GO:0006925 inflammatory cell apoptotic process Added SYNONYM killing of inflammatory cells
2003-10-22 GO:0006926 virus-infected cell apoptotic process Added SYNONYM killing virus-infected cells
2003-10-22 GO:0006927 transformed cell apoptotic process Added SYNONYM killing transformed cells
2003-10-22 GO:0007342 fusion of sperm to egg plasma membrane Added SYNONYM sperm-oocyte fusion
2003-10-22 GO:0007507 heart development Added SYNONYM dorsal vessel development
2003-10-22 GO:0010002 cardioblast differentiation Added SYNONYM cardiomyocyte generation
2003-10-22 GO:0043011 myeloid dendritic cell differentiation Added SYNONYM Langerhans cell differentiation
2003-10-22 GO:0043012 regulation of fusion of sperm to egg plasma membrane Added SYNONYM regulation of sperm-oocyte fusion
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added SYNONYM inhibition of sperm-oocyte fusion
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added SYNONYM negative regulation of sperm-oocyte fusion
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added SYNONYM proteoglycan sulfate transfer
2003-10-22 GO:0050701 interleukin-1 secretion Added SYNONYM IL-1 secretion
2003-10-22 GO:0050702 interleukin-1 beta secretion Added SYNONYM IL-1b secretion
2003-10-22 GO:0050703 interleukin-1 alpha secretion Added SYNONYM IL-1a secretion
2003-10-22 GO:0007507 heart development Added SECONDARY GO:0007511 (dorsal vessel development)
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added XREF EC:2.8.2.-
2003-10-22 GO:0007340 acrosome reaction Added DEFINITION The discharge, by sperm, of a single, anterior secretory granule following their attachment to the zona pellucida surrounding the oocyte.
2003-10-22 GO:0007512 adult heart development Added DEFINITION Generation and development of the heart of a fully developed and mature organism.
2003-10-22 GO:0035052 dorsal vessel aortic cell fate commitment Added DEFINITION The commitment of cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells, as seen in Drosophila.
2003-10-22 GO:0050700 CARD domain binding Added DEFINITION Interacting selectively with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.
2003-10-22 GO:0035051 cardiocyte differentiation Added DEFINITION The processes whereby a relatively unspecialized cell acquires the specialized stuctural and/or functional features of a cell that will form part of the cardiac organ of an individual.
2003-10-22 GO:0010002 cardioblast differentiation Updated DEFINITION The process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast.
2003-10-22 GO:0016358 dendrite development Added DEFINITION Formation and development of a dendrite, a freely branching protoplasmic process of a nerve cell.
2003-10-22 GO:0043011 myeloid dendritic cell differentiation Added DEFINITION The process by which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and haemopoietic systems and skin.
2003-10-22 GO:0043009 chordate embryonic development Added DEFINITION The embryonic development of a vertebrate from zygote formation until birth.
2003-10-22 GO:0045824 negative regulation of innate immune response Updated DEFINITION Any process that stops, prevents or reduces the rate of the innate immune response.
2003-10-22 GO:0035054 embryonic heart tube anterior/posterior pattern specification Added DEFINITION The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.
2003-10-22 GO:0035050 embryonic heart tube development Added DEFINITION Generation and development of the embryonic heart tube.
2003-10-22 GO:0043010 camera-type eye development Added DEFINITION The formation and development of the vertebrate eye.
2003-10-22 GO:0007342 fusion of sperm to egg plasma membrane Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2003-10-22 GO:0035053 dorsal vessel heart proper cell fate commitment Added DEFINITION The commitment of cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells, as seen in Drosophila.
2003-10-22 GO:0050719 interleukin-1 alpha biosynthetic process Added DEFINITION The formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050703 interleukin-1 alpha secretion Added DEFINITION The regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050707 regulation of cytokine secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells.
2003-10-22 GO:0043012 regulation of fusion of sperm to egg plasma membrane Added DEFINITION Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane.
2003-10-22 GO:0050727 regulation of inflammatory response Added DEFINITION Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
2003-10-22 GO:0050721 regulation of interleukin-1 alpha biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050705 regulation of interleukin-1 alpha secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050722 regulation of interleukin-1 beta biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050706 regulation of interleukin-1 beta secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell or group of cells.
2003-10-22 GO:0050704 regulation of interleukin-1 secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell or group of cells.
2003-10-22 GO:0035055 regulation of nuclear mRNA splicing via U2-type spliceosome Added DEFINITION Any process that modulates the frequency, rate or extent of mRNA splicing via a U2-type spliceosome.
2003-10-22 GO:0050708 regulation of protein secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2003-10-22 GO:0047368 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity Updated DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine 4-sulfate + 3'-phosphoadenosine 5'-phosphosulfate (PAPS) = UDP-N-acetyl-D-galactosamine 4,6-bissulfate + adenosine 3',5'-bisphosphate.
2003-10-22 GO:0050699 WW domain binding Added DEFINITION Interacting selectively with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
2003-10-22 GO:0050720 interleukin-1 beta biosynthetic process Added DEFINITION The formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050702 interleukin-1 beta secretion Added DEFINITION The regulated release of interleukin 1 beta from a cell or group of cells.
2003-10-22 GO:0050701 interleukin-1 secretion Added DEFINITION The regulated release of interleukin-1 from a cell or group of cells. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response.
2003-10-22 GO:0007508 larval heart development Added DEFINITION Generation and development of the larval heart. In Drosophila the larval heart (dorsal vessel) is a continous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.
2003-10-22 GO:0050710 negative regulation of cytokine secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of cytokines from a cell or group of cells.
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added DEFINITION Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.
2003-10-22 GO:0050728 negative regulation of inflammatory response Added DEFINITION Any process that stops, prevents or reduces the rate of the inflammatory response.
2003-10-22 GO:0050723 negative regulation of interleukin-1 alpha biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050712 negative regulation of interleukin-1 alpha secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050724 negative regulation of interleukin-1 beta biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050713 negative regulation of interleukin-1 beta secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of interleukin-1 beta from a cell or group of cells.
2003-10-22 GO:0050711 negative regulation of interleukin-1 secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of interleukin-1 from a cell or group of cells.
2003-10-22 GO:0035056 negative regulation of nuclear mRNA splicing via U2-type spliceosome Added DEFINITION Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a U2-type spliceosome.
2003-10-22 GO:0050709 negative regulation of protein secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of a protein from a cell or group of cells.
2003-10-22 GO:0007341 penetration of zona pellucida Added DEFINITION The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
2003-10-22 GO:0007513 pericardial cell differentiation Added DEFINITION The process whereby a relatively unspecialized mesodermal cell acquires specialized structural and/or functional features of a pericardial cell. In insects, pericardial cells are loosely arranged non-myogenic cells that flank the cardioblasts and probably act in the filtration of hemolymph.
2003-10-22 GO:0050715 positive regulation of cytokine secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of cytokines from a cell or group of cells.
2003-10-22 GO:0050729 positive regulation of inflammatory response Added DEFINITION Any process that activates or increases the rate of the inflammatory response.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2003-10-22 GO:0007511 dorsal vessel development Deleted TERM dorsal vessel development
2003-10-22 GO:0007513 pericardial cell differentiation Updated TERM pericardial cell differentiation
2003-10-22 GO:0006924 activation-induced cell death of T cells Updated TERM programmed cell death, activated T-cells
2003-10-22 GO:0006925 inflammatory cell apoptotic process Updated TERM programmed cell death, inflammatory cells
2003-10-22 GO:0006926 virus-infected cell apoptotic process Updated TERM programmed cell death, virus-infected cells
2003-10-22 GO:0006927 transformed cell apoptotic process Updated TERM programmed cell death, transformed cells
2003-10-22 GO:0035050 embryonic heart tube development Added TERM embryonic heart tube development
2003-10-22 GO:0035051 cardiocyte differentiation Added TERM cardiac cell differentiation
2003-10-22 GO:0035052 dorsal vessel aortic cell fate commitment Added TERM aortic cell fate commitment (sensu Drosophila)
2003-10-22 GO:0035053 dorsal vessel heart proper cell fate commitment Added TERM heart proper cell fate commitment (sensu Drosophila)
2003-10-22 GO:0035054 embryonic heart tube anterior/posterior pattern specification Added TERM embryonic heart tube anterior/posterior pattern formation
2003-10-22 GO:0035055 regulation of nuclear mRNA splicing via U2-type spliceosome Added TERM regulation of nuclear mRNA splicing via U2-type spliceosome
2003-10-22 GO:0035056 negative regulation of nuclear mRNA splicing via U2-type spliceosome Added TERM negative regulation of nuclear mRNA splicing via U2-type spliceosome
2003-10-22 GO:0035057 positive regulation of nuclear mRNA splicing via U2-type spliceosome Added TERM positive regulation of nuclear mRNA splicing via U2-type spliceosome
2003-10-22 GO:0043009 chordate embryonic development Added TERM embryonic development (sensu Vertebrata)
2003-10-22 GO:0043010 camera-type eye development Added TERM eye morphogenesis (sensu Vertebrata)
2003-10-22 GO:0043011 myeloid dendritic cell differentiation Added TERM dendritic cell differentiation
2003-10-22 GO:0043012 regulation of fusion of sperm to egg plasma membrane Added TERM regulation of fusion of sperm to egg plasma membrane
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added TERM negative regulation of fusion of sperm to egg plasma membrane
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added TERM proteoglycan sulfotransferase activity
2003-10-22 GO:0050699 WW domain binding Added TERM WW domain binding
2003-10-22 GO:0050700 CARD domain binding Added TERM CARD domain binding
2003-10-22 GO:0050701 interleukin-1 secretion Added TERM interleukin-1 secretion
2003-10-22 GO:0050702 interleukin-1 beta secretion Added TERM interleukin-1 beta secretion
2003-10-22 GO:0050703 interleukin-1 alpha secretion Added TERM interleukin-1 alpha secretion
2003-10-22 GO:0050704 regulation of interleukin-1 secretion Added TERM regulation of interleukin-1 secretion
2003-10-22 GO:0050705 regulation of interleukin-1 alpha secretion Added TERM regulation of interleukin-1 alpha secretion
2003-10-22 GO:0050706 regulation of interleukin-1 beta secretion Added TERM regulation of interleukin-1 beta secretion
2003-10-22 GO:0050707 regulation of cytokine secretion Added TERM regulation of cytokine secretion
2003-10-22 GO:0050708 regulation of protein secretion Added TERM regulation of protein secretion
2003-10-22 GO:0050709 negative regulation of protein secretion Added TERM negative regulation of protein secretion
2003-10-22 GO:0050710 negative regulation of cytokine secretion Added TERM negative regulation of cytokine secretion
2003-10-22 GO:0050711 negative regulation of interleukin-1 secretion Added TERM negative regulation of interleukin-1 secretion
2003-10-22 GO:0050712 negative regulation of interleukin-1 alpha secretion Added TERM negative regulation of interleukin-1 alpha secretion
2003-10-22 GO:0050713 negative regulation of interleukin-1 beta secretion Added TERM negative regulation of interleukin-1 beta secretion
2003-10-22 GO:0050714 positive regulation of protein secretion Added TERM positive regulation of protein secretion
2003-10-22 GO:0050715 positive regulation of cytokine secretion Added TERM positive regulation of cytokine secretion
2003-10-22 GO:0050716 positive regulation of interleukin-1 secretion Added TERM positive regulation of interleukin-1 secretion
2003-10-22 GO:0050717 positive regulation of interleukin-1 alpha secretion Added TERM positive regulation of interleukin-1 alpha secretion
2003-10-22 GO:0050718 positive regulation of interleukin-1 beta secretion Added TERM positive regulation of interleukin-1 beta secretion
2003-10-22 GO:0050719 interleukin-1 alpha biosynthetic process Added TERM interleukin-1 alpha biosynthesis
2003-10-22 GO:0050720 interleukin-1 beta biosynthetic process Added TERM interleukin-1 beta biosynthesis
2003-10-22 GO:0050721 regulation of interleukin-1 alpha biosynthetic process Added TERM regulation of interleukin-1 alpha biosynthesis
2003-10-22 GO:0050722 regulation of interleukin-1 beta biosynthetic process Added TERM regulation of interleukin-1 beta biosynthesis
2003-10-22 GO:0050723 negative regulation of interleukin-1 alpha biosynthetic process Added TERM negative regulation of interleukin-1 alpha biosynthesis
2003-10-22 GO:0050724 negative regulation of interleukin-1 beta biosynthetic process Added TERM negative regulation of interleukin-1 beta biosynthesis
2003-10-22 GO:0050725 positive regulation of interleukin-1 beta biosynthetic process Added TERM positive regulation of interleukin-1 beta biosynthesis
2003-10-22 GO:0050726 positive regulation of interleukin-1 alpha biosynthetic process Added TERM positive regulation of interleukin-1 alpha biosynthesis
2003-10-22 GO:0050727 regulation of inflammatory response Added TERM regulation of inflammatory response
2003-10-22 GO:0050728 negative regulation of inflammatory response Added TERM negative regulation of inflammatory response
2003-10-22 GO:0050729 positive regulation of inflammatory response Added TERM positive regulation of inflammatory response

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2003-10-22 GO:0050726 positive regulation of interleukin-1 alpha biosynthetic process Added DEFINITION Any process that activates or increases the rate of the formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050717 positive regulation of interleukin-1 alpha secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050725 positive regulation of interleukin-1 beta biosynthetic process Added DEFINITION Any process that activates or increases the rate of the formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050718 positive regulation of interleukin-1 beta secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of interleukin-1 beta from a cell or group of cells.
2003-10-22 GO:0050716 positive regulation of interleukin-1 secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of interleukin-1 from a cell or group of cells.
2003-10-22 GO:0035057 positive regulation of nuclear mRNA splicing via U2-type spliceosome Added DEFINITION Any process that activates or increases the rate or extent of mRNA splicing via a U2-type spliceosome.
2003-10-22 GO:0050714 positive regulation of protein secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of a protein from a cell or group of cells.
2003-10-22 GO:0001526 proteoglycan sulfate transfer Updated DEFINITION OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate.
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added DEFINITION Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate (PAPS) + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.
2003-10-22 GO:0006924 activation-induced cell death of T cells Added SYNONYM peripheral killing of activated T-cells
2003-10-22 GO:0006925 inflammatory cell apoptotic process Added SYNONYM killing of inflammatory cells
2003-10-22 GO:0006926 virus-infected cell apoptotic process Added SYNONYM killing virus-infected cells
2003-10-22 GO:0006927 transformed cell apoptotic process Added SYNONYM killing transformed cells
2003-10-22 GO:0007342 fusion of sperm to egg plasma membrane Added SYNONYM sperm-oocyte fusion
2003-10-22 GO:0007507 heart development Added SYNONYM dorsal vessel development
2003-10-22 GO:0010002 cardioblast differentiation Added SYNONYM cardiomyocyte generation
2003-10-22 GO:0043011 myeloid dendritic cell differentiation Added SYNONYM Langerhans cell differentiation
2003-10-22 GO:0043012 regulation of fusion of sperm to egg plasma membrane Added SYNONYM regulation of sperm-oocyte fusion
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added SYNONYM inhibition of sperm-oocyte fusion
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added SYNONYM negative regulation of sperm-oocyte fusion
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added SYNONYM proteoglycan sulfate transfer
2003-10-22 GO:0050701 interleukin-1 secretion Added SYNONYM IL-1 secretion
2003-10-22 GO:0050702 interleukin-1 beta secretion Added SYNONYM IL-1b secretion
2003-10-22 GO:0050703 interleukin-1 alpha secretion Added SYNONYM IL-1a secretion
2003-10-22 GO:0007340 acrosome reaction Added DEFINITION The discharge, by sperm, of a single, anterior secretory granule following their attachment to the zona pellucida surrounding the oocyte.
2003-10-22 GO:0007512 adult heart development Added DEFINITION Generation and development of the heart of a fully developed and mature organism.
2003-10-22 GO:0035052 dorsal vessel aortic cell fate commitment Added DEFINITION The commitment of cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells, as seen in Drosophila.
2003-10-22 GO:0050700 CARD domain binding Added DEFINITION Interacting selectively with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.
2003-10-22 GO:0035051 cardiocyte differentiation Added DEFINITION The processes whereby a relatively unspecialized cell acquires the specialized stuctural and/or functional features of a cell that will form part of the cardiac organ of an individual.
2003-10-22 GO:0010002 cardioblast differentiation Updated DEFINITION The process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast.
2003-10-22 GO:0016358 dendrite development Added DEFINITION Formation and development of a dendrite, a freely branching protoplasmic process of a nerve cell.
2003-10-22 GO:0043011 myeloid dendritic cell differentiation Added DEFINITION The process by which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and haemopoietic systems and skin.
2003-10-22 GO:0043009 chordate embryonic development Added DEFINITION The embryonic development of a vertebrate from zygote formation until birth.
2003-10-22 GO:0045824 negative regulation of innate immune response Updated DEFINITION Any process that stops, prevents or reduces the rate of the innate immune response.
2003-10-22 GO:0035054 embryonic heart tube anterior/posterior pattern specification Added DEFINITION The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.
2003-10-22 GO:0035050 embryonic heart tube development Added DEFINITION Generation and development of the embryonic heart tube.
2003-10-22 GO:0043010 camera-type eye development Added DEFINITION The formation and development of the vertebrate eye.
2003-10-22 GO:0007342 fusion of sperm to egg plasma membrane Added DEFINITION The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
2003-10-22 GO:0035053 dorsal vessel heart proper cell fate commitment Added DEFINITION The commitment of cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells, as seen in Drosophila.
2003-10-22 GO:0050719 interleukin-1 alpha biosynthetic process Added DEFINITION The formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050703 interleukin-1 alpha secretion Added DEFINITION The regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050707 regulation of cytokine secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells.
2003-10-22 GO:0043012 regulation of fusion of sperm to egg plasma membrane Added DEFINITION Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane.
2003-10-22 GO:0050727 regulation of inflammatory response Added DEFINITION Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
2003-10-22 GO:0050721 regulation of interleukin-1 alpha biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050705 regulation of interleukin-1 alpha secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050722 regulation of interleukin-1 beta biosynthetic process Added DEFINITION Any process that modulates the frequency, rate or extent of the formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050706 regulation of interleukin-1 beta secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell or group of cells.
2003-10-22 GO:0050704 regulation of interleukin-1 secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell or group of cells.
2003-10-22 GO:0035055 regulation of nuclear mRNA splicing via U2-type spliceosome Added DEFINITION Any process that modulates the frequency, rate or extent of mRNA splicing via a U2-type spliceosome.
2003-10-22 GO:0050708 regulation of protein secretion Added DEFINITION Any process that modulates the frequency, rate or extent of the regulated release of a protein from a cell or group of cells.
2003-10-22 GO:0047368 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity Updated DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine 4-sulfate + 3'-phosphoadenosine 5'-phosphosulfate (PAPS) = UDP-N-acetyl-D-galactosamine 4,6-bissulfate + adenosine 3',5'-bisphosphate.
2003-10-22 GO:0050699 WW domain binding Added DEFINITION Interacting selectively with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
2003-10-22 GO:0050720 interleukin-1 beta biosynthetic process Added DEFINITION The formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050702 interleukin-1 beta secretion Added DEFINITION The regulated release of interleukin 1 beta from a cell or group of cells.
2003-10-22 GO:0050701 interleukin-1 secretion Added DEFINITION The regulated release of interleukin-1 from a cell or group of cells. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response.
2003-10-22 GO:0007508 larval heart development Added DEFINITION Generation and development of the larval heart. In Drosophila the larval heart (dorsal vessel) is a continous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.
2003-10-22 GO:0050710 negative regulation of cytokine secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of cytokines from a cell or group of cells.
2003-10-22 GO:0043013 negative regulation of fusion of sperm to egg plasma membrane Added DEFINITION Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.
2003-10-22 GO:0050728 negative regulation of inflammatory response Added DEFINITION Any process that stops, prevents or reduces the rate of the inflammatory response.
2003-10-22 GO:0050723 negative regulation of interleukin-1 alpha biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of interleukin-1 alpha.
2003-10-22 GO:0050712 negative regulation of interleukin-1 alpha secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of interleukin-1 alpha from a cell or group of cells.
2003-10-22 GO:0050724 negative regulation of interleukin-1 beta biosynthetic process Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of interleukin-1 beta.
2003-10-22 GO:0050713 negative regulation of interleukin-1 beta secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of interleukin-1 beta from a cell or group of cells.
2003-10-22 GO:0050711 negative regulation of interleukin-1 secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of interleukin-1 from a cell or group of cells.
2003-10-22 GO:0035056 negative regulation of nuclear mRNA splicing via U2-type spliceosome Added DEFINITION Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a U2-type spliceosome.
2003-10-22 GO:0050709 negative regulation of protein secretion Added DEFINITION Any process that stops, prevents or reduces the rate of the regulated release of a protein from a cell or group of cells.
2003-10-22 GO:0007341 penetration of zona pellucida Added DEFINITION The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
2003-10-22 GO:0007513 pericardial cell differentiation Added DEFINITION The process whereby a relatively unspecialized mesodermal cell acquires specialized structural and/or functional features of a pericardial cell. In insects, pericardial cells are loosely arranged non-myogenic cells that flank the cardioblasts and probably act in the filtration of hemolymph.
2003-10-22 GO:0050715 positive regulation of cytokine secretion Added DEFINITION Any process that activates or increases the rate of the regulated release of cytokines from a cell or group of cells.
2003-10-22 GO:0050729 positive regulation of inflammatory response Added DEFINITION Any process that activates or increases the rate of the inflammatory response.

Cross-references

Timestamp GO ID GO Term Name Action Category Detail
2003-10-22 GO:0050698 proteoglycan sulfotransferase activity Added XREF EC:2.8.2.-

Other

Timestamp GO ID GO Term Name Action Category Detail
2003-10-22 GO:0007507 heart development Added SECONDARY GO:0007511 (dorsal vessel development)
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