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GO Term History: Displaying 116 audit records for all terms for the date 2003-08-22

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2003-08-22 GO:0004392 heme oxygenase (decyclizing) activity Updated DEFINITION Catalysis of the reaction: heme + 3 donor-H2 + 3 O2 = biliverdin + Fe2+ + CO + 3 acceptor + 3 H2O.
2003-08-22 GO:0000358 formation of catalytic U2-type spliceosome for second transesterification step Added DEFINITION Conformational rearrangement of the U2-type spliceosomal complex containing the RNA products of the first step of splicing to form the catalytic site for the second step of splicing.
2003-08-22 GO:0000353 formation of quadruple SL/U4/U5/U6 snRNP Added DEFINITION Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.
2003-08-22 GO:0000372 Group I intron splicing Added DEFINITION The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).
2003-08-22 GO:0000373 Group II intron splicing Added DEFINITION The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.
2003-08-22 GO:0000368 U2-type nuclear mRNA 5'-splice site recognition Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling U2-type spliceosome. This may involve binding of U1 snRNA and/or U6 snRNA to intron sequences.
2003-08-22 GO:0000370 U2-type nuclear mRNA branch site recognition Added DEFINITION Recognition of the intron branch site sequence by components of the assembling U2-type spliceosome for a cis-splicing reaction. This recognition may include an interaction between the U2 snRNA (as part of the U2 snRNP) and the branch site sequence of the pre-mRNA. In cis-splicing, the U1 snRNP, already associated with the 5'-splice site may also be involved in recruiting the U2 snRNP to the branch site.
2003-08-22 GO:0000396 U2-type spliceosome conformational change to release U4 and U1 Added DEFINITION Rearrangement of the pre-catalytic spliceosome containing U4 and U1 snRNPs to unpair U4 from U6 and release it from the spliceosomal complex along with U1.
2003-08-22 GO:0000391 U2-type spliceosome disassembly Added DEFINITION Dissembly of the U2-type spliceosome with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. The other product is the excised sequence. In cis splicing, this forms a lariat structure.
2003-08-22 GO:0047496 vesicle transport along microtubule Added DEFINITION The directed movement of a vesicle along a microtubule, mediated by motor proteins.
2003-08-22 GO:0047060 (R)-pantolactone dehydrogenase (flavin) activity Updated DEFINITION Catalysis of the reaction: acceptor + pantoyl lactone = reduced acceptor + 2-dehydropantoyl lactone.
2003-08-22 GO:0000384 first spliceosomal transesterification activity Added DEFINITION Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.
2003-08-22 GO:0000363 obsolete first U12-type spliceosomal transesterification activity Added DEFINITION Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins.
2003-08-22 GO:0000362 obsolete first U2-type spliceosomal transesterification activity Added DEFINITION Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins.
2003-08-22 GO:0000386 second spliceosomal transesterification activity Added DEFINITION Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM fructosylinvertase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM glucosucrase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM invertase
2003-08-22 GO:0000362 obsolete first U2-type spliceosomal transesterification activity Added SYNONYM lariat formation, 5'-splice site cleavage
2003-08-22 GO:0000363 obsolete first U12-type spliceosomal transesterification activity Added SYNONYM lariat formation, 5'-splice site cleavage
2003-08-22 GO:0000364 obsolete second U2-type spliceosomal transesterification activity Added SYNONYM 3'-splice site cleavage, exon ligation
2003-08-22 GO:0000367 obsolete second U12-type spliceosomal transesterification activity Added SYNONYM 3'-splice site cleavage, exon ligation
2003-08-22 GO:0000384 first spliceosomal transesterification activity Added SYNONYM lariat formation, 5'-splice site cleavage
2003-08-22 GO:0000386 second spliceosomal transesterification activity Added SYNONYM 3'-splice site cleavage, exon ligation
2003-08-22 GO:0047497 mitochondrion transport along microtubule Added SYNONYM mitochondrial transport along microtubule
2003-08-22 GO:0000104 succinate dehydrogenase activity Deleted SYNONYM fumarate reductase
2003-08-22 GO:0003988 acetyl-CoA C-acyltransferase activity Deleted SYNONYM 2-keto-acyl thiolase
2003-08-22 GO:0004558 alpha-1,4-glucosidase activity Deleted SYNONYM alpha-glucosidase II
2003-08-22 GO:0004558 alpha-1,4-glucosidase activity Deleted SYNONYM maltase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM acid invertase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM invertin
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM maxinvert L 1000
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM saccharase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM sucrase
2003-08-22 GO:0004630 phospholipase D activity Deleted SYNONYM choline phosphatase
2003-08-22 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Deleted SYNONYM ribonucleotide reductase
2003-08-22 GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Deleted SYNONYM PTS transporter
2003-08-22 GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Deleted SYNONYM phosphotransfer-driven group translocator
2003-08-22 GO:0009924 octadecanal decarbonylase activity Deleted SYNONYM octadecanal alkane-lyase
2003-08-22 GO:0009924 octadecanal decarbonylase activity Deleted SYNONYM octadecanal decarbonylase
2003-08-22 GO:0016711 flavonoid 3'-monooxygenase activity Deleted SYNONYM flavonoid 3'-hydroxylase
2003-08-22 GO:0016719 carotene 7,8-desaturase activity Deleted SYNONYM zeta-carotene desaturase
2003-08-22 GO:0016767 geranylgeranyl-diphosphate geranylgeranyltransferase activity Deleted SYNONYM phytoene synthase
2003-08-22 GO:0019153 protein-disulfide reductase (glutathione) activity Deleted SYNONYM glutaredoxin reductase
2003-08-22 GO:0019153 protein-disulfide reductase (glutathione) activity Deleted SYNONYM glutathione-insulin transhydrogenase
2003-08-22 GO:0030599 pectinesterase activity Deleted SYNONYM pectin methylesterase activity
2003-08-22 GO:0045430 chalcone isomerase activity Deleted SYNONYM chalcone-flavanone isomerase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM alkaline invertase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM beta-D-fructofuranoside fructohydrolase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM beta-fructosidase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM beta-h-fructosidase
2003-08-22 GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Deleted XREF TC:4.A.-.-.-
2003-08-22 GO:0000384 first spliceosomal transesterification activity Added TERM 1st spliceosomal transesterification activity
2003-08-22 GO:0000385 spliceosomal catalysis Added TERM spliceosomal catalysis
2003-08-22 GO:0000386 second spliceosomal transesterification activity Added TERM 2nd spliceosomal transesterification activity
2003-08-22 GO:0000362 obsolete first U2-type spliceosomal transesterification activity Added TERM 1st U2-type spliceosomal transesterification activity
2003-08-22 GO:0000363 obsolete first U12-type spliceosomal transesterification activity Added TERM 1st U12-type spliceosomal transesterification activity
2003-08-22 GO:0000364 obsolete second U2-type spliceosomal transesterification activity Added TERM 2nd U2-type spliceosomal transesterification activity
2003-08-22 GO:0000367 obsolete second U12-type spliceosomal transesterification activity Added TERM 2nd U12-type spliceosomal transesterification activity
2003-08-22 GO:0035003 subapical complex Added TERM subapical complex
2003-08-22 GO:0047496 vesicle transport along microtubule Added TERM vesicle transport along microtubule
2003-08-22 GO:0047497 mitochondrion transport along microtubule Added TERM mitochondrion transport along microtubule
2003-08-22 GO:0000367 obsolete second U12-type spliceosomal transesterification activity Added DEFINITION Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.
2003-08-22 GO:0000364 obsolete second U2-type spliceosomal transesterification activity Added DEFINITION Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.
2003-08-22 GO:0018690 4-methoxybenzoate monooxygenase (O-demethylating) activity Updated DEFINITION Catalysis of the reaction: 4-methoxybenzoate + donor-H2 + O2 = 4-hydroxybenzoate + formaldehyde + acceptor + H2O.
2003-08-22 GO:0045300 acyl-[acyl-carrier-protein] desaturase activity Updated DEFINITION Catalysis of the reaction: stearoyl-(acyl-carrier protein) + donor-H2 + O2 = oleoyl-(acyl-carrier protein) + acceptor + H2O. The enzyme requires ferredoxin.
2003-08-22 GO:0000380 alternative mRNA splicing, via spliceosome Added DEFINITION The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
2003-08-22 GO:0000351 assembly of spliceosomal tri-snRNP U4/U6.U5 Added DEFINITION The formation of a tri-snRNP complex containing the U4, U6, and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP to form the tri-snRNP that is ready to reassemble into another U2-type spliceosome complex.
2003-08-22 GO:0000355 assembly of spliceosomal tri-snRNP U4atac/U6atac.U5 Added DEFINITION The formation of a tri-snRNP complex containing the U4atac, U6atac, and U5 snRNAs and associated proteins. This includes reannealing of U4atac and U6atac snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP as well as the subsequent association of the U5 snRNP with the U4atac/U6atac snRNP to form a tri-snRNP that is ready to reassemble into another U12-type spliceosome complex.
2003-08-22 GO:0000385 spliceosomal catalysis Added DEFINITION Catalysis of a transesterification reaction that is part of spliceosomal mRNA splicing.
2003-08-22 GO:0000393 spliceosomal conformational changes to generate catalytic conformation Added DEFINITION Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.
2003-08-22 GO:0000387 spliceosomal snRNP assembly Added DEFINITION The formation and assembly from one or more snRNA and multiple protein components of a ribonucleoprotein complex that in involved in formation of the spliceosome.
2003-08-22 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) Added DEFINITION Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).
2003-08-22 GO:0000390 spliceosomal complex disassembly Added DEFINITION Dissembly of the spliceosome with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.
2003-08-22 GO:0004768 stearoyl-CoA 9-desaturase activity Updated DEFINITION Catalysis of the reaction: stearoyl-CoA + reduced acceptor + O2 = oleoyl-CoA + acceptor + 2 H2O.
2003-08-22 GO:0004508 steroid 17-alpha-monooxygenase activity Updated DEFINITION Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2003-08-22 GO:0004509 steroid 21-monooxygenase activity Updated DEFINITION Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O.
2003-08-22 GO:0035003 subapical complex Added DEFINITION The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
2003-08-22 GO:0004800 thyroxine 5'-deiodinase activity Updated DEFINITION Catalysis of the reaction: L-thyroxine + donor-H2 = 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+.
2003-08-22 GO:0000352 trans assembly of SL-containing precatalytic spliceosome Added DEFINITION Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.
2003-08-22 GO:0000379 tRNA-type intron splice site recognition and cleavage Added DEFINITION The process of recognition of the tertiary structure of a tRNA type intron and the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites.
2003-08-22 GO:0000357 U12-type catalytic spliceosome formation for first transesterification step Added DEFINITION Formation of a catalytic U12-type spliceosome complex containing the pre-mRNA ready to perform the first splicing reaction.
2003-08-22 GO:0000382 U12-type nuclear mRNA 3'-splice site recognition Added DEFINITION Recognition of the intron 3'-splice site by components of the assembling U12-type spliceosome.
2003-08-22 GO:0000369 U12-type nuclear mRNA 5'-splice site recognition Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling U12-type spliceosome. The U11 snRNP is thought to play a role in recognition of the U12-type 5'-splice site.
2003-08-22 GO:0000371 U12-type nuclear mRNA branch site recognition Added DEFINITION Recognition of the intron branch site sequence by components of the assembling U12-type spliceosome. The U12 snRNP is thought to play a role in this via an interaction between the U12 snRNA and the branch site sequence of the pre-mRNA.
2003-08-22 GO:0000397 U12-type spliceosome conformational change to release U4atac and U11 Added DEFINITION Rearrangement of the pre-catalytic spliceosome containing U4atac and U11 snRNPs to unpair U4atac from U6atac and release it from the spliceosomal complex along with U11.
2003-08-22 GO:0000392 U12-type spliceosome disassembly Added DEFINITION Dissembly of the U12-type spliceosome with the ATP-dependent release of the RNA composed of the joined exons and the lariat intron RNA.
2003-08-22 GO:0000356 U2-type catalytic spliceosome formation for first transesterification step Added DEFINITION Formation of a catalytic U2-type spliceosome complex containing the pre-mRNA ready to perform the first splicing reaction.
2003-08-22 GO:0000383 U2-type nuclear mRNA 3'-splice site recognition Added DEFINITION Recognition of the intron 3'-splice site by components of the assembling U2-type spliceosome.
2003-08-22 GO:0000374 Group III intron splicing Added DEFINITION The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.
2003-08-22 GO:0000366 intergenic mRNA trans splicing Added DEFINITION The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.
2003-08-22 GO:0016213 linoleoyl-CoA desaturase activity Updated DEFINITION Catalysis of the reaction: linoleoyl-CoA + donor-H2 + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.
2003-08-22 GO:0047497 mitochondrion transport along microtubule Added DEFINITION The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
2003-08-22 GO:0000389 mRNA 3'-splice site recognition Added DEFINITION Recognition of the intron 3'-splice site by components of the assembling U12-type spliceosome.
2003-08-22 GO:0000395 mRNA 5'-splice site recognition Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling spliceosome.
2003-08-22 GO:0000348 mRNA branch site recognition Added DEFINITION Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.
2003-08-22 GO:0000365 mRNA trans splicing, via spliceosome Added DEFINITION The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2003-08-22 GO:0047489 pectate disaccharide-lyase activity Updated DEFINITION Catalysis of the eliminative cleavage of 4-(4-deoxy-a-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i. e. de-esterified pectin.
2003-08-22 GO:0004666 prostaglandin-endoperoxide synthase activity Updated DEFINITION Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2003-08-22 GO:0000381 regulation of alternative mRNA splicing, via spliceosome Added DEFINITION Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
2003-08-22 GO:0000378 RNA exon ligation Added DEFINITION The process of joining two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction.
2003-08-22 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation Added DEFINITION Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
2003-08-22 GO:0000375 RNA splicing, via transesterification reactions Added DEFINITION Splicing of RNA via a series of two transesterification reactions.
2003-08-22 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile Added DEFINITION Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.
2003-08-22 GO:0000376 RNA splicing, via transesterification reactions with guanosine as nucleophile Added DEFINITION Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.
2003-08-22 GO:0018522 benzoyl-CoA reductase activity Updated DEFINITION Catalysis of the reaction: benzoyl-CoA + donor-H2 + 2 ATP = cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP + 2 phosphate.
2003-08-22 GO:0016719 carotene 7,8-desaturase activity Updated DEFINITION Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.
2003-08-22 GO:0000354 cis assembly of pre-catalytic spliceosome Added DEFINITION Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
2003-08-22 GO:0000361 cis assembly of U12-type pre-catalytic spliceosome Added DEFINITION Assembly of a U12-type spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the U4atac-Uatac6/U5 tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
2003-08-22 GO:0000360 cis assembly of U2-type pre-catalytic spliceosome Added DEFINITION Assembly of a U2-type spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the U4-U6/U5 tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
2003-08-22 GO:0016720 delta12-fatty acid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: linoleate + donor-H2 + O2 = crepenynate + acceptor + H2O.
2003-08-22 GO:0019135 deoxyhypusine monooxygenase activity Updated DEFINITION Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
2003-08-22 GO:0004501 ecdysone 20-monooxygenase activity Updated DEFINITION Catalysis of the reaction: ecdysone + donor-H2 + O2 = 20-hydroxyecdysone + acceptor + H2O.
2003-08-22 GO:0000349 generation of catalytic spliceosome for first transesterification step Added DEFINITION Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
2003-08-22 GO:0000350 generation of catalytic spliceosome for second transesterification step Added DEFINITION Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
2003-08-22 GO:0000359 formation of catalytic U12-type spliceosome for second transesterification step Added DEFINITION Conformational rearrangement of the U12-type spliceosomal complex containing the RNA products of the 1st step of splicing to form the catalytic site for the second step of splicing.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2003-08-22 GO:0000384 first spliceosomal transesterification activity Added TERM 1st spliceosomal transesterification activity
2003-08-22 GO:0000385 spliceosomal catalysis Added TERM spliceosomal catalysis
2003-08-22 GO:0000386 second spliceosomal transesterification activity Added TERM 2nd spliceosomal transesterification activity
2003-08-22 GO:0000362 obsolete first U2-type spliceosomal transesterification activity Added TERM 1st U2-type spliceosomal transesterification activity
2003-08-22 GO:0000363 obsolete first U12-type spliceosomal transesterification activity Added TERM 1st U12-type spliceosomal transesterification activity
2003-08-22 GO:0000364 obsolete second U2-type spliceosomal transesterification activity Added TERM 2nd U2-type spliceosomal transesterification activity
2003-08-22 GO:0000367 obsolete second U12-type spliceosomal transesterification activity Added TERM 2nd U12-type spliceosomal transesterification activity
2003-08-22 GO:0035003 subapical complex Added TERM subapical complex
2003-08-22 GO:0047496 vesicle transport along microtubule Added TERM vesicle transport along microtubule
2003-08-22 GO:0047497 mitochondrion transport along microtubule Added TERM mitochondrion transport along microtubule

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2003-08-22 GO:0004392 heme oxygenase (decyclizing) activity Updated DEFINITION Catalysis of the reaction: heme + 3 donor-H2 + 3 O2 = biliverdin + Fe2+ + CO + 3 acceptor + 3 H2O.
2003-08-22 GO:0000358 formation of catalytic U2-type spliceosome for second transesterification step Added DEFINITION Conformational rearrangement of the U2-type spliceosomal complex containing the RNA products of the first step of splicing to form the catalytic site for the second step of splicing.
2003-08-22 GO:0000353 formation of quadruple SL/U4/U5/U6 snRNP Added DEFINITION Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.
2003-08-22 GO:0000372 Group I intron splicing Added DEFINITION The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).
2003-08-22 GO:0000373 Group II intron splicing Added DEFINITION The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.
2003-08-22 GO:0000368 U2-type nuclear mRNA 5'-splice site recognition Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling U2-type spliceosome. This may involve binding of U1 snRNA and/or U6 snRNA to intron sequences.
2003-08-22 GO:0000370 U2-type nuclear mRNA branch site recognition Added DEFINITION Recognition of the intron branch site sequence by components of the assembling U2-type spliceosome for a cis-splicing reaction. This recognition may include an interaction between the U2 snRNA (as part of the U2 snRNP) and the branch site sequence of the pre-mRNA. In cis-splicing, the U1 snRNP, already associated with the 5'-splice site may also be involved in recruiting the U2 snRNP to the branch site.
2003-08-22 GO:0000396 U2-type spliceosome conformational change to release U4 and U1 Added DEFINITION Rearrangement of the pre-catalytic spliceosome containing U4 and U1 snRNPs to unpair U4 from U6 and release it from the spliceosomal complex along with U1.
2003-08-22 GO:0000391 U2-type spliceosome disassembly Added DEFINITION Dissembly of the U2-type spliceosome with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. The other product is the excised sequence. In cis splicing, this forms a lariat structure.
2003-08-22 GO:0047496 vesicle transport along microtubule Added DEFINITION The directed movement of a vesicle along a microtubule, mediated by motor proteins.
2003-08-22 GO:0047060 (R)-pantolactone dehydrogenase (flavin) activity Updated DEFINITION Catalysis of the reaction: acceptor + pantoyl lactone = reduced acceptor + 2-dehydropantoyl lactone.
2003-08-22 GO:0000384 first spliceosomal transesterification activity Added DEFINITION Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.
2003-08-22 GO:0000363 obsolete first U12-type spliceosomal transesterification activity Added DEFINITION Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins.
2003-08-22 GO:0000362 obsolete first U2-type spliceosomal transesterification activity Added DEFINITION Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins.
2003-08-22 GO:0000386 second spliceosomal transesterification activity Added DEFINITION Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM fructosylinvertase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM glucosucrase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM invertase
2003-08-22 GO:0000362 obsolete first U2-type spliceosomal transesterification activity Added SYNONYM lariat formation, 5'-splice site cleavage
2003-08-22 GO:0000363 obsolete first U12-type spliceosomal transesterification activity Added SYNONYM lariat formation, 5'-splice site cleavage
2003-08-22 GO:0000364 obsolete second U2-type spliceosomal transesterification activity Added SYNONYM 3'-splice site cleavage, exon ligation
2003-08-22 GO:0000367 obsolete second U12-type spliceosomal transesterification activity Added SYNONYM 3'-splice site cleavage, exon ligation
2003-08-22 GO:0000384 first spliceosomal transesterification activity Added SYNONYM lariat formation, 5'-splice site cleavage
2003-08-22 GO:0000386 second spliceosomal transesterification activity Added SYNONYM 3'-splice site cleavage, exon ligation
2003-08-22 GO:0047497 mitochondrion transport along microtubule Added SYNONYM mitochondrial transport along microtubule
2003-08-22 GO:0000104 succinate dehydrogenase activity Deleted SYNONYM fumarate reductase
2003-08-22 GO:0003988 acetyl-CoA C-acyltransferase activity Deleted SYNONYM 2-keto-acyl thiolase
2003-08-22 GO:0004558 alpha-1,4-glucosidase activity Deleted SYNONYM alpha-glucosidase II
2003-08-22 GO:0004558 alpha-1,4-glucosidase activity Deleted SYNONYM maltase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM acid invertase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM invertin
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM maxinvert L 1000
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM saccharase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM sucrase
2003-08-22 GO:0004630 phospholipase D activity Deleted SYNONYM choline phosphatase
2003-08-22 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Deleted SYNONYM ribonucleotide reductase
2003-08-22 GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Deleted SYNONYM PTS transporter
2003-08-22 GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Deleted SYNONYM phosphotransfer-driven group translocator
2003-08-22 GO:0009924 octadecanal decarbonylase activity Deleted SYNONYM octadecanal alkane-lyase
2003-08-22 GO:0009924 octadecanal decarbonylase activity Deleted SYNONYM octadecanal decarbonylase
2003-08-22 GO:0016711 flavonoid 3'-monooxygenase activity Deleted SYNONYM flavonoid 3'-hydroxylase
2003-08-22 GO:0016719 carotene 7,8-desaturase activity Deleted SYNONYM zeta-carotene desaturase
2003-08-22 GO:0016767 geranylgeranyl-diphosphate geranylgeranyltransferase activity Deleted SYNONYM phytoene synthase
2003-08-22 GO:0019153 protein-disulfide reductase (glutathione) activity Deleted SYNONYM glutaredoxin reductase
2003-08-22 GO:0019153 protein-disulfide reductase (glutathione) activity Deleted SYNONYM glutathione-insulin transhydrogenase
2003-08-22 GO:0030599 pectinesterase activity Deleted SYNONYM pectin methylesterase activity
2003-08-22 GO:0045430 chalcone isomerase activity Deleted SYNONYM chalcone-flavanone isomerase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM alkaline invertase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM beta-D-fructofuranoside fructohydrolase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM beta-fructosidase
2003-08-22 GO:0004564 beta-fructofuranosidase activity Deleted SYNONYM beta-h-fructosidase
2003-08-22 GO:0000367 obsolete second U12-type spliceosomal transesterification activity Added DEFINITION Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.
2003-08-22 GO:0000364 obsolete second U2-type spliceosomal transesterification activity Added DEFINITION Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.
2003-08-22 GO:0018690 4-methoxybenzoate monooxygenase (O-demethylating) activity Updated DEFINITION Catalysis of the reaction: 4-methoxybenzoate + donor-H2 + O2 = 4-hydroxybenzoate + formaldehyde + acceptor + H2O.
2003-08-22 GO:0045300 acyl-[acyl-carrier-protein] desaturase activity Updated DEFINITION Catalysis of the reaction: stearoyl-(acyl-carrier protein) + donor-H2 + O2 = oleoyl-(acyl-carrier protein) + acceptor + H2O. The enzyme requires ferredoxin.
2003-08-22 GO:0000380 alternative mRNA splicing, via spliceosome Added DEFINITION The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
2003-08-22 GO:0000351 assembly of spliceosomal tri-snRNP U4/U6.U5 Added DEFINITION The formation of a tri-snRNP complex containing the U4, U6, and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP to form the tri-snRNP that is ready to reassemble into another U2-type spliceosome complex.
2003-08-22 GO:0000355 assembly of spliceosomal tri-snRNP U4atac/U6atac.U5 Added DEFINITION The formation of a tri-snRNP complex containing the U4atac, U6atac, and U5 snRNAs and associated proteins. This includes reannealing of U4atac and U6atac snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP as well as the subsequent association of the U5 snRNP with the U4atac/U6atac snRNP to form a tri-snRNP that is ready to reassemble into another U12-type spliceosome complex.
2003-08-22 GO:0000385 spliceosomal catalysis Added DEFINITION Catalysis of a transesterification reaction that is part of spliceosomal mRNA splicing.
2003-08-22 GO:0000393 spliceosomal conformational changes to generate catalytic conformation Added DEFINITION Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.
2003-08-22 GO:0000387 spliceosomal snRNP assembly Added DEFINITION The formation and assembly from one or more snRNA and multiple protein components of a ribonucleoprotein complex that in involved in formation of the spliceosome.
2003-08-22 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) Added DEFINITION Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).
2003-08-22 GO:0000390 spliceosomal complex disassembly Added DEFINITION Dissembly of the spliceosome with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.
2003-08-22 GO:0004768 stearoyl-CoA 9-desaturase activity Updated DEFINITION Catalysis of the reaction: stearoyl-CoA + reduced acceptor + O2 = oleoyl-CoA + acceptor + 2 H2O.
2003-08-22 GO:0004508 steroid 17-alpha-monooxygenase activity Updated DEFINITION Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2003-08-22 GO:0004509 steroid 21-monooxygenase activity Updated DEFINITION Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O.
2003-08-22 GO:0035003 subapical complex Added DEFINITION The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
2003-08-22 GO:0004800 thyroxine 5'-deiodinase activity Updated DEFINITION Catalysis of the reaction: L-thyroxine + donor-H2 = 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+.
2003-08-22 GO:0000352 trans assembly of SL-containing precatalytic spliceosome Added DEFINITION Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.
2003-08-22 GO:0000379 tRNA-type intron splice site recognition and cleavage Added DEFINITION The process of recognition of the tertiary structure of a tRNA type intron and the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites.
2003-08-22 GO:0000357 U12-type catalytic spliceosome formation for first transesterification step Added DEFINITION Formation of a catalytic U12-type spliceosome complex containing the pre-mRNA ready to perform the first splicing reaction.
2003-08-22 GO:0000382 U12-type nuclear mRNA 3'-splice site recognition Added DEFINITION Recognition of the intron 3'-splice site by components of the assembling U12-type spliceosome.
2003-08-22 GO:0000369 U12-type nuclear mRNA 5'-splice site recognition Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling U12-type spliceosome. The U11 snRNP is thought to play a role in recognition of the U12-type 5'-splice site.
2003-08-22 GO:0000371 U12-type nuclear mRNA branch site recognition Added DEFINITION Recognition of the intron branch site sequence by components of the assembling U12-type spliceosome. The U12 snRNP is thought to play a role in this via an interaction between the U12 snRNA and the branch site sequence of the pre-mRNA.
2003-08-22 GO:0000397 U12-type spliceosome conformational change to release U4atac and U11 Added DEFINITION Rearrangement of the pre-catalytic spliceosome containing U4atac and U11 snRNPs to unpair U4atac from U6atac and release it from the spliceosomal complex along with U11.
2003-08-22 GO:0000392 U12-type spliceosome disassembly Added DEFINITION Dissembly of the U12-type spliceosome with the ATP-dependent release of the RNA composed of the joined exons and the lariat intron RNA.
2003-08-22 GO:0000356 U2-type catalytic spliceosome formation for first transesterification step Added DEFINITION Formation of a catalytic U2-type spliceosome complex containing the pre-mRNA ready to perform the first splicing reaction.
2003-08-22 GO:0000383 U2-type nuclear mRNA 3'-splice site recognition Added DEFINITION Recognition of the intron 3'-splice site by components of the assembling U2-type spliceosome.
2003-08-22 GO:0000374 Group III intron splicing Added DEFINITION The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.
2003-08-22 GO:0000366 intergenic mRNA trans splicing Added DEFINITION The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.
2003-08-22 GO:0016213 linoleoyl-CoA desaturase activity Updated DEFINITION Catalysis of the reaction: linoleoyl-CoA + donor-H2 + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.
2003-08-22 GO:0047497 mitochondrion transport along microtubule Added DEFINITION The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
2003-08-22 GO:0000389 mRNA 3'-splice site recognition Added DEFINITION Recognition of the intron 3'-splice site by components of the assembling U12-type spliceosome.
2003-08-22 GO:0000395 mRNA 5'-splice site recognition Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling spliceosome.
2003-08-22 GO:0000348 mRNA branch site recognition Added DEFINITION Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.
2003-08-22 GO:0000365 mRNA trans splicing, via spliceosome Added DEFINITION The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
2003-08-22 GO:0047489 pectate disaccharide-lyase activity Updated DEFINITION Catalysis of the eliminative cleavage of 4-(4-deoxy-a-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i. e. de-esterified pectin.
2003-08-22 GO:0004666 prostaglandin-endoperoxide synthase activity Updated DEFINITION Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
2003-08-22 GO:0000381 regulation of alternative mRNA splicing, via spliceosome Added DEFINITION Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
2003-08-22 GO:0000378 RNA exon ligation Added DEFINITION The process of joining two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction.
2003-08-22 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation Added DEFINITION Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
2003-08-22 GO:0000375 RNA splicing, via transesterification reactions Added DEFINITION Splicing of RNA via a series of two transesterification reactions.
2003-08-22 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile Added DEFINITION Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.
2003-08-22 GO:0000376 RNA splicing, via transesterification reactions with guanosine as nucleophile Added DEFINITION Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.
2003-08-22 GO:0018522 benzoyl-CoA reductase activity Updated DEFINITION Catalysis of the reaction: benzoyl-CoA + donor-H2 + 2 ATP = cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP + 2 phosphate.
2003-08-22 GO:0016719 carotene 7,8-desaturase activity Updated DEFINITION Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.
2003-08-22 GO:0000354 cis assembly of pre-catalytic spliceosome Added DEFINITION Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
2003-08-22 GO:0000361 cis assembly of U12-type pre-catalytic spliceosome Added DEFINITION Assembly of a U12-type spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the U4atac-Uatac6/U5 tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
2003-08-22 GO:0000360 cis assembly of U2-type pre-catalytic spliceosome Added DEFINITION Assembly of a U2-type spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the U4-U6/U5 tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
2003-08-22 GO:0016720 delta12-fatty acid dehydrogenase activity Updated DEFINITION Catalysis of the reaction: linoleate + donor-H2 + O2 = crepenynate + acceptor + H2O.
2003-08-22 GO:0019135 deoxyhypusine monooxygenase activity Updated DEFINITION Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
2003-08-22 GO:0004501 ecdysone 20-monooxygenase activity Updated DEFINITION Catalysis of the reaction: ecdysone + donor-H2 + O2 = 20-hydroxyecdysone + acceptor + H2O.
2003-08-22 GO:0000349 generation of catalytic spliceosome for first transesterification step Added DEFINITION Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
2003-08-22 GO:0000350 generation of catalytic spliceosome for second transesterification step Added DEFINITION Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
2003-08-22 GO:0000359 formation of catalytic U12-type spliceosome for second transesterification step Added DEFINITION Conformational rearrangement of the U12-type spliceosomal complex containing the RNA products of the 1st step of splicing to form the catalytic site for the second step of splicing.

Cross-references

Timestamp GO ID GO Term Name Action Category Detail
2003-08-22 GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity Deleted XREF TC:4.A.-.-.-
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