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GO Term History: Displaying 58 audit records for all terms for the date 2003-08-06

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2003-08-06 GO:0048190 wing disc dorsal/ventral pattern formation Added TERM wing disc dorsal/ventral pattern formation
2003-08-06 GO:0048001 erythrose-4-phosphate dehydrogenase activity Deleted SYNONYM E4PDH
2003-08-06 GO:0018610 dibenzofuran 4,4a-dioxygenase activity Added DEFINITION Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.
2003-08-06 GO:0019104 DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
2003-08-06 GO:0003896 DNA primase activity Updated DEFINITION Catalysis of the synthesis of short RNA primers for the Okazaki fragments on both DNA template strands at the replication fork. A DNA-directed RNA polymerase that forms a complex with alpha DNA polymerase.
2003-08-06 GO:0019175 alpha-ribazole-5'-P phosphatase activity Added DEFINITION Catalysis of the reaction: alpha-ribazole-5'-phosphate = alpha-ribazole + phosphate.
2003-08-06 GO:0016842 amidine-lyase activity Updated DEFINITION Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.
2003-08-06 GO:0016843 amine-lyase activity Updated DEFINITION Catalysis of the release of amides by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.
2003-08-06 GO:0016841 ammonia-lyase activity Updated DEFINITION Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
2003-08-06 GO:0019132 obsolete C-terminal processing peptidase activity Updated DEFINITION Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.
2003-08-06 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor Updated DEFINITION Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction.
2003-08-06 GO:0016840 carbon-nitrogen lyase activity Updated DEFINITION Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e. g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e. g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e. g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i. e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
2003-08-06 GO:0003917 DNA topoisomerase type I activity Updated DEFINITION Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
2003-08-06 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity Updated DEFINITION Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
2003-08-06 GO:0042283 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Updated DEFINITION Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
2003-08-06 GO:0016835 carbon-oxygen lyase activity Updated DEFINITION Catalysis of the breakage of a carbon-oxygen bond.
2003-08-06 GO:0016838 carbon-oxygen lyase activity, acting on phosphates Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.
2003-08-06 GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
2003-08-06 GO:0016846 carbon-sulfur lyase activity Updated DEFINITION Catalysis of the elimination of H2S or substituted H2S.
2003-08-06 GO:0008809 carnitine racemase activity Added DEFINITION Catalysis of the reaction: D-carnitine = L-carnitine.
2003-08-06 GO:0003824 catalytic activity Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-08-06 GO:0004568 chitinase activity Updated DEFINITION Catalysis of the random hydrolysis of N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
2003-08-06 GO:0009975 cyclase activity Updated DEFINITION Catalysis of a ring closure reaction.
2003-08-06 GO:0008826 cysteine sulfinate desulfinase activity Added DEFINITION Catalysis of the reaction: 3-sulfinoalanine = L-alanine + SO3(2-).
2003-08-06 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Updated DEFINITION Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
2003-08-06 GO:0007450 dorsal/ventral pattern formation, imaginal disc Added DEFINITION The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
2003-08-06 GO:0004175 endopeptidase activity Updated DEFINITION Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides, and comprising any enzyme of sub-subclasses EC:3.4.21-99. They are classfied according to the presence of essential catalytic residues or ions at their active sites.
2003-08-06 GO:0009974 zeinoxanthin epsilon hydroxylase activity Updated DEFINITION Catalysis of the hydroxylation of zeinoxanthin to lutein. Adds hydroxy group to the epsilon ring of the alpha-carotene.
2003-08-06 GO:0048001 erythrose-4-phosphate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: erythrose 4-phosphate + NAD+ = erythronate-4-phosphate + NADH + H+. A step in the pathway to 4-hydroxy-L-threonine, a precursor of pyridoxine.
2003-08-06 GO:0004338 glucan exo-1,3-beta-glucosidase activity Updated DEFINITION Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of 1,3-beta-D-glucans, releasing alpha-glucose.
2003-08-06 GO:0003924 GTPase activity Updated DEFINITION Catalysis of the hydrolysis of GTP to GDP and orthophosphate.
2003-08-06 GO:0004415 hyalurononglucosaminidase activity Updated DEFINITION Catalysis of the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
2003-08-06 GO:0016836 hydro-lyase activity Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2003-08-06 GO:0009678 hydrogen-translocating pyrophosphatase activity Updated DEFINITION Catalysis of the hydrolysis of pyrophoshate, which generates a proton motive force.
2003-08-06 GO:0042380 hydroxymethylbutenyl pyrophosphate reductase activity Updated DEFINITION Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.
2003-08-06 GO:0008384 IkappaB kinase activity Updated DEFINITION Catalysis of the phosphorylation of IkappaB, thereby targeting this for proteasomal degradation and allowing the nuclear translocation of kB. Composed of alpha, beta and gamma subunits, the latter not having kinase activity but presumed to play a regulatory role.
2003-08-06 GO:0016948 iron hydrogenase activity Updated DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. Iron-sulfur-containing hydrogenase ((Fe) hydrogenase) with two ferredoxin-type (4Fe-4S) clusters and an atypical iron-sulfur center believed to be involved in the activation of H2. The (Fe) hydrogenase has the highest specific activity in the evolution and consumption of hydrogen and in the proton-deuterium exchange reaction and this enzyme is the most sensitive to CO and NO2-.
2003-08-06 GO:0045289 luciferin monooxygenase activity Updated DEFINITION Catalysis of the oxidation of luciferin. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.
2003-08-06 GO:0016829 lyase activity Updated DEFINITION Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
2003-08-06 GO:0004707 MAP kinase activity Updated DEFINITION Catalysis of the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
2003-08-06 GO:0019178 NADP phosphatase activity Added DEFINITION Catalysis of the reaction: H2O + NADP = NAD + phosphate.
2003-08-06 GO:0016950 nickel-iron hydrogenase activity Updated DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. Nickel-(iron-sulfur)-containing hydrogenases (( NiFe) hydrogenases) possess two (4Fe-4S) centers and one (3Fe-xS) cluster in addition to nickel. The redox active nickel is ligated by at least two cysteinyl thiolate residues and the (NiFe) hydrogenases are particularly resistant to inhibitors such as CO and NO2-.
2003-08-06 GO:0016951 nickel-iron-selenium hydrogenase activity Updated DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. The nickel-(iron-sulfur)-selenium-containing hydrogenases ((NiFe-Se) hydrogenases) which contain nickel and selenium in equimolecular amounts plus (4Fe-4S) centers.
2003-08-06 GO:0008571 obsolete non-chaperonin molecular chaperone ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin.
2003-08-06 GO:0016845 obsolete other carbon-nitrogen lyase activity Updated DEFINITION Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.
2003-08-06 GO:0016839 obsolete other carbon-oxygen lyase activity Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.
2003-08-06 GO:0004650 polygalacturonase activity Updated DEFINITION Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2003-08-06 GO:0003808 obsolete protein C (activated) activity Updated DEFINITION Catalysis of the degradation of blood coagulation factors Va and VIIIa.
2003-08-06 GO:0003756 protein disulfide isomerase activity Updated DEFINITION Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins to form the native structures.
2003-08-06 GO:0007449 proximal/distal pattern formation, imaginal disc Added DEFINITION The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
2003-08-06 GO:0015046 rubredoxin-NADP reductase activity Updated DEFINITION Catalysis of the reactions: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+ and reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.
2003-08-06 GO:0016909 SAP kinase activity Updated DEFINITION Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines.
2003-08-06 GO:0048100 wing disc anterior/posterior pattern formation Updated DEFINITION The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.
2003-08-06 GO:0048190 wing disc dorsal/ventral pattern formation Added DEFINITION The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
2003-08-06 GO:0000908 taurine dioxygenase activity Deleted SYNONYM alpha-ketoglutarate-dependent taurine dioxygenase
2003-08-06 GO:0046481 digalactosyldiacylglycerol synthase activity Deleted SYNONYM DGD2
2003-08-06 GO:0046481 digalactosyldiacylglycerol synthase activity Deleted SYNONYM digalactosyldiacylglycerol synthase 2
2003-08-06 GO:0030305 heparanase activity Updated DEFINITION Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2003-08-06 GO:0048190 wing disc dorsal/ventral pattern formation Added TERM wing disc dorsal/ventral pattern formation

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2003-08-06 GO:0048001 erythrose-4-phosphate dehydrogenase activity Deleted SYNONYM E4PDH
2003-08-06 GO:0018610 dibenzofuran 4,4a-dioxygenase activity Added DEFINITION Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.
2003-08-06 GO:0019104 DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
2003-08-06 GO:0003896 DNA primase activity Updated DEFINITION Catalysis of the synthesis of short RNA primers for the Okazaki fragments on both DNA template strands at the replication fork. A DNA-directed RNA polymerase that forms a complex with alpha DNA polymerase.
2003-08-06 GO:0019175 alpha-ribazole-5'-P phosphatase activity Added DEFINITION Catalysis of the reaction: alpha-ribazole-5'-phosphate = alpha-ribazole + phosphate.
2003-08-06 GO:0016842 amidine-lyase activity Updated DEFINITION Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.
2003-08-06 GO:0016843 amine-lyase activity Updated DEFINITION Catalysis of the release of amides by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.
2003-08-06 GO:0016841 ammonia-lyase activity Updated DEFINITION Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
2003-08-06 GO:0019132 obsolete C-terminal processing peptidase activity Updated DEFINITION Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.
2003-08-06 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor Updated DEFINITION Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction.
2003-08-06 GO:0016840 carbon-nitrogen lyase activity Updated DEFINITION Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e. g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e. g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e. g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i. e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
2003-08-06 GO:0003917 DNA topoisomerase type I activity Updated DEFINITION Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
2003-08-06 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity Updated DEFINITION Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
2003-08-06 GO:0042283 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Updated DEFINITION Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
2003-08-06 GO:0016835 carbon-oxygen lyase activity Updated DEFINITION Catalysis of the breakage of a carbon-oxygen bond.
2003-08-06 GO:0016838 carbon-oxygen lyase activity, acting on phosphates Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.
2003-08-06 GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
2003-08-06 GO:0016846 carbon-sulfur lyase activity Updated DEFINITION Catalysis of the elimination of H2S or substituted H2S.
2003-08-06 GO:0008809 carnitine racemase activity Added DEFINITION Catalysis of the reaction: D-carnitine = L-carnitine.
2003-08-06 GO:0003824 catalytic activity Updated DEFINITION Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
2003-08-06 GO:0004568 chitinase activity Updated DEFINITION Catalysis of the random hydrolysis of N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
2003-08-06 GO:0009975 cyclase activity Updated DEFINITION Catalysis of a ring closure reaction.
2003-08-06 GO:0008826 cysteine sulfinate desulfinase activity Added DEFINITION Catalysis of the reaction: 3-sulfinoalanine = L-alanine + SO3(2-).
2003-08-06 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Updated DEFINITION Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
2003-08-06 GO:0007450 dorsal/ventral pattern formation, imaginal disc Added DEFINITION The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
2003-08-06 GO:0004175 endopeptidase activity Updated DEFINITION Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides, and comprising any enzyme of sub-subclasses EC:3.4.21-99. They are classfied according to the presence of essential catalytic residues or ions at their active sites.
2003-08-06 GO:0009974 zeinoxanthin epsilon hydroxylase activity Updated DEFINITION Catalysis of the hydroxylation of zeinoxanthin to lutein. Adds hydroxy group to the epsilon ring of the alpha-carotene.
2003-08-06 GO:0048001 erythrose-4-phosphate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: erythrose 4-phosphate + NAD+ = erythronate-4-phosphate + NADH + H+. A step in the pathway to 4-hydroxy-L-threonine, a precursor of pyridoxine.
2003-08-06 GO:0004338 glucan exo-1,3-beta-glucosidase activity Updated DEFINITION Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of 1,3-beta-D-glucans, releasing alpha-glucose.
2003-08-06 GO:0003924 GTPase activity Updated DEFINITION Catalysis of the hydrolysis of GTP to GDP and orthophosphate.
2003-08-06 GO:0004415 hyalurononglucosaminidase activity Updated DEFINITION Catalysis of the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
2003-08-06 GO:0016836 hydro-lyase activity Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2003-08-06 GO:0009678 hydrogen-translocating pyrophosphatase activity Updated DEFINITION Catalysis of the hydrolysis of pyrophoshate, which generates a proton motive force.
2003-08-06 GO:0042380 hydroxymethylbutenyl pyrophosphate reductase activity Updated DEFINITION Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.
2003-08-06 GO:0008384 IkappaB kinase activity Updated DEFINITION Catalysis of the phosphorylation of IkappaB, thereby targeting this for proteasomal degradation and allowing the nuclear translocation of kB. Composed of alpha, beta and gamma subunits, the latter not having kinase activity but presumed to play a regulatory role.
2003-08-06 GO:0016948 iron hydrogenase activity Updated DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. Iron-sulfur-containing hydrogenase ((Fe) hydrogenase) with two ferredoxin-type (4Fe-4S) clusters and an atypical iron-sulfur center believed to be involved in the activation of H2. The (Fe) hydrogenase has the highest specific activity in the evolution and consumption of hydrogen and in the proton-deuterium exchange reaction and this enzyme is the most sensitive to CO and NO2-.
2003-08-06 GO:0045289 luciferin monooxygenase activity Updated DEFINITION Catalysis of the oxidation of luciferin. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.
2003-08-06 GO:0016829 lyase activity Updated DEFINITION Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
2003-08-06 GO:0004707 MAP kinase activity Updated DEFINITION Catalysis of the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
2003-08-06 GO:0019178 NADP phosphatase activity Added DEFINITION Catalysis of the reaction: H2O + NADP = NAD + phosphate.
2003-08-06 GO:0016950 nickel-iron hydrogenase activity Updated DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. Nickel-(iron-sulfur)-containing hydrogenases (( NiFe) hydrogenases) possess two (4Fe-4S) centers and one (3Fe-xS) cluster in addition to nickel. The redox active nickel is ligated by at least two cysteinyl thiolate residues and the (NiFe) hydrogenases are particularly resistant to inhibitors such as CO and NO2-.
2003-08-06 GO:0016951 nickel-iron-selenium hydrogenase activity Updated DEFINITION Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2. The nickel-(iron-sulfur)-selenium-containing hydrogenases ((NiFe-Se) hydrogenases) which contain nickel and selenium in equimolecular amounts plus (4Fe-4S) centers.
2003-08-06 GO:0008571 obsolete non-chaperonin molecular chaperone ATPase activity Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin.
2003-08-06 GO:0016845 obsolete other carbon-nitrogen lyase activity Updated DEFINITION Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.
2003-08-06 GO:0016839 obsolete other carbon-oxygen lyase activity Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.
2003-08-06 GO:0004650 polygalacturonase activity Updated DEFINITION Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
2003-08-06 GO:0003808 obsolete protein C (activated) activity Updated DEFINITION Catalysis of the degradation of blood coagulation factors Va and VIIIa.
2003-08-06 GO:0003756 protein disulfide isomerase activity Updated DEFINITION Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins to form the native structures.
2003-08-06 GO:0007449 proximal/distal pattern formation, imaginal disc Added DEFINITION The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
2003-08-06 GO:0015046 rubredoxin-NADP reductase activity Updated DEFINITION Catalysis of the reactions: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+ and reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.
2003-08-06 GO:0016909 SAP kinase activity Updated DEFINITION Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines.
2003-08-06 GO:0048100 wing disc anterior/posterior pattern formation Updated DEFINITION The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.
2003-08-06 GO:0048190 wing disc dorsal/ventral pattern formation Added DEFINITION The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
2003-08-06 GO:0000908 taurine dioxygenase activity Deleted SYNONYM alpha-ketoglutarate-dependent taurine dioxygenase
2003-08-06 GO:0046481 digalactosyldiacylglycerol synthase activity Deleted SYNONYM DGD2
2003-08-06 GO:0046481 digalactosyldiacylglycerol synthase activity Deleted SYNONYM digalactosyldiacylglycerol synthase 2
2003-08-06 GO:0030305 heparanase activity Updated DEFINITION Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.
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126ms