spacer

GO Term History: Displaying 39 audit records for all terms for the date 2003-08-05

From (YYYY-MM-DD):
To (YYYY-MM-DD):
Period:
Category:
Terms:
Limit:
Date Specification

You can specify an explicit date range that you are interested in by setting the "From" and "To" parameters; this will limit the data displayed to those changes that were recorded within that (inclusive) date range.

Alternatively, you can use the "Period" parameter to view the GO term changes that occurred over a specific number of Day(s), Week(s), Month(s) or Year(s) before a specified date.

If you do not enter a "To" date, then the period will be relative to the current date. If, however, you do specify a "To" value, then the "Period" value will display records in the timeframe up to and including that specified date.

Category

You can use this field to specify what types of term changes you are interested in seeing.

Terms

You can enter a list of GO Terms in this field to limit the changes displayed. Please note that only changes made to directly listed terms will be displayed, not term descendants.

Limit

The default number of records returned is 500, however you can increase or decrease this limit. In order to prevent possible browser problems, the maximum upper limit is 10,000.

Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2003-08-05 GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2003-08-05 GO:0004844 uracil DNA N-glycosylase activity Updated DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.
2003-08-05 GO:0009984 adenylate forming enzyme activity Updated DEFINITION Catalysis of the reaction: substrate + ATP = substrate-AMP + PPi.
2003-08-05 GO:0009978 allene oxide synthase activity Updated DEFINITION Catalysis of the conversion of 13(S)-hydroperoxylinoleic acid to 12,13,-epoxylinoleic acid.
2003-08-05 GO:0009916 alternative oxidase activity Updated DEFINITION Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.
2003-08-05 GO:0046988 asioloorosomucoid beta-1,3-glucuronosyltransferase activity Added DEFINITION Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.
2003-08-05 GO:0016443 bidentate ribonuclease III activity Updated DEFINITION Catalysis of the digestion of double-stranded RNAs into 22-nucleotide products that then associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.
2003-08-05 GO:0009981 callose synthase activity Updated DEFINITION Catalysis of the reaction involving the synthesis of callose.
2003-08-05 GO:0046989 galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity Added DEFINITION Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.
2003-08-05 GO:0046973 histone lysine N-methyltransferase activity (H3-K24 specific) Updated DEFINITION OBSOLETE. Catalysis of the addition of a methyl group onto lysine at position 24 of the histone H3 protein.
2003-08-05 GO:0004708 MAP kinase kinase activity Updated DEFINITION Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in MAP kinases. It is a dual-specificity mitogen-activated protein kinase kinase and requires activation by the serine/threonine kinase, MAP kinase kinase kinase.
2003-08-05 GO:0000700 mismatch base pair DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
2003-08-05 GO:0004497 monooxygenase activity Updated DEFINITION Catalysis of the incorporation by an oxidoreductase of only one atom of oxygen from dioxygen into the donor.
2003-08-05 GO:0042408 myrcene/(E)-beta-ocimene synthase activity Updated DEFINITION Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes.
2003-08-05 GO:0046987 N-acetyllactosamine beta-1,3-glucuronosyltransferase activity Added DEFINITION Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).
2003-08-05 GO:0000702 oxidized base lesion DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
2003-08-05 GO:0048044 para-hydroxybenzoate-polyprenyl diphosphate transferase activity Updated DEFINITION Catalysis of the condensation of p-hydroxybenzoate and polyprenyl diphosphate in ubiquinone biosynthesis.
2003-08-05 GO:0045024 peptidyl-glutamyl peptide hydrolyzing enzyme activity Updated DEFINITION Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids.
2003-08-05 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.
2003-08-05 GO:0004620 phospholipase activity Updated DEFINITION Catalysis of the hydrolysis of a glycerophospholipid.
2003-08-05 GO:0004652 polynucleotide adenylyltransferase activity Updated DEFINITION Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
2003-08-05 GO:0017120 polyphosphatidylinositol phosphatase activity Updated DEFINITION Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.
2003-08-05 GO:0008984 protein-glutamate methylesterase activity Updated DEFINITION Catalysis of the hydrolyis of peptidyl-L-glutamate 5-methyl ester to peptidyl-L-glutamate.
2003-08-05 GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.
2003-08-05 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
2003-08-05 GO:0000704 pyrimidine dimer DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
2003-08-05 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.
2003-08-05 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity Updated DEFINITION Catalysis of the formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. Enzymes with this activity recognize and remove oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
2003-08-05 GO:0030580 quinone cofactor methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone, menaquinone, plastoquinone and phylloquinone.
2003-08-05 GO:0042499 signal peptide peptidase activity Updated DEFINITION Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein.
2003-08-05 GO:0017065 single-strand selective uracil DNA N-glycosylase activity Updated DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2003-08-05 GO:0009917 sterol 5-alpha reductase activity Updated DEFINITION Catalysis of the removal of a C-5 double bond in the B ring of a sterol.
2003-08-05 GO:0009918 sterol delta7 reductase activity Updated DEFINITION Catalysis of the reduction of a sterol at the delta-7 position.
2003-08-05 GO:0009976 tocopherol cyclase activity Updated DEFINITION Catalysis of the synthesis of both tocopherols and tocotrienols.
2003-08-05 GO:0009983 tyrosine aminopeptidase activity Updated DEFINITION Catalysis of the release of N-terminal tyrosine from a peptide.
2003-08-05 GO:0009037 tyrosine-based site-specific recombinase activity Updated DEFINITION Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.
2003-08-05 GO:0017005 3'-tyrosyl-DNA phosphodiesterase activity Updated DEFINITION Catalysis of the hydrolysis of covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I (GO:0003917) and DNA.
2003-08-05 GO:0004221 ubiquitin thiolesterase activity Updated DEFINITION Catalysis of the hydrolysis of esters formed between thiols and the C-terminal glycine residue of the polypeptide ubiquitin, and of AMP-ubiquitin.
2003-08-05 GO:0046820 4-amino-4-deoxychorismate synthase activity Updated DEFINITION Catalysis of the reaction: chorismate + glutamine = 4-amino-4-deoxychorismic acid + glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); The first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2003-08-05 GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity Updated DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2003-08-05 GO:0004844 uracil DNA N-glycosylase activity Updated DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.
2003-08-05 GO:0009984 adenylate forming enzyme activity Updated DEFINITION Catalysis of the reaction: substrate + ATP = substrate-AMP + PPi.
2003-08-05 GO:0009978 allene oxide synthase activity Updated DEFINITION Catalysis of the conversion of 13(S)-hydroperoxylinoleic acid to 12,13,-epoxylinoleic acid.
2003-08-05 GO:0009916 alternative oxidase activity Updated DEFINITION Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.
2003-08-05 GO:0046988 asioloorosomucoid beta-1,3-glucuronosyltransferase activity Added DEFINITION Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.
2003-08-05 GO:0016443 bidentate ribonuclease III activity Updated DEFINITION Catalysis of the digestion of double-stranded RNAs into 22-nucleotide products that then associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.
2003-08-05 GO:0009981 callose synthase activity Updated DEFINITION Catalysis of the reaction involving the synthesis of callose.
2003-08-05 GO:0046989 galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity Added DEFINITION Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.
2003-08-05 GO:0046973 histone lysine N-methyltransferase activity (H3-K24 specific) Updated DEFINITION OBSOLETE. Catalysis of the addition of a methyl group onto lysine at position 24 of the histone H3 protein.
2003-08-05 GO:0004708 MAP kinase kinase activity Updated DEFINITION Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in MAP kinases. It is a dual-specificity mitogen-activated protein kinase kinase and requires activation by the serine/threonine kinase, MAP kinase kinase kinase.
2003-08-05 GO:0000700 mismatch base pair DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
2003-08-05 GO:0004497 monooxygenase activity Updated DEFINITION Catalysis of the incorporation by an oxidoreductase of only one atom of oxygen from dioxygen into the donor.
2003-08-05 GO:0042408 myrcene/(E)-beta-ocimene synthase activity Updated DEFINITION Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes.
2003-08-05 GO:0046987 N-acetyllactosamine beta-1,3-glucuronosyltransferase activity Added DEFINITION Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).
2003-08-05 GO:0000702 oxidized base lesion DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
2003-08-05 GO:0048044 para-hydroxybenzoate-polyprenyl diphosphate transferase activity Updated DEFINITION Catalysis of the condensation of p-hydroxybenzoate and polyprenyl diphosphate in ubiquinone biosynthesis.
2003-08-05 GO:0045024 peptidyl-glutamyl peptide hydrolyzing enzyme activity Updated DEFINITION Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids.
2003-08-05 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity Updated DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.
2003-08-05 GO:0004620 phospholipase activity Updated DEFINITION Catalysis of the hydrolysis of a glycerophospholipid.
2003-08-05 GO:0004652 polynucleotide adenylyltransferase activity Updated DEFINITION Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
2003-08-05 GO:0017120 polyphosphatidylinositol phosphatase activity Updated DEFINITION Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.
2003-08-05 GO:0008984 protein-glutamate methylesterase activity Updated DEFINITION Catalysis of the hydrolyis of peptidyl-L-glutamate 5-methyl ester to peptidyl-L-glutamate.
2003-08-05 GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.
2003-08-05 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
2003-08-05 GO:0000704 pyrimidine dimer DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
2003-08-05 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity Updated DEFINITION Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.
2003-08-05 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity Updated DEFINITION Catalysis of the formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. Enzymes with this activity recognize and remove oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
2003-08-05 GO:0030580 quinone cofactor methyltransferase activity Updated DEFINITION Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone, menaquinone, plastoquinone and phylloquinone.
2003-08-05 GO:0042499 signal peptide peptidase activity Updated DEFINITION Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein.
2003-08-05 GO:0017065 single-strand selective uracil DNA N-glycosylase activity Updated DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2003-08-05 GO:0009917 sterol 5-alpha reductase activity Updated DEFINITION Catalysis of the removal of a C-5 double bond in the B ring of a sterol.
2003-08-05 GO:0009918 sterol delta7 reductase activity Updated DEFINITION Catalysis of the reduction of a sterol at the delta-7 position.
2003-08-05 GO:0009976 tocopherol cyclase activity Updated DEFINITION Catalysis of the synthesis of both tocopherols and tocotrienols.
2003-08-05 GO:0009983 tyrosine aminopeptidase activity Updated DEFINITION Catalysis of the release of N-terminal tyrosine from a peptide.
2003-08-05 GO:0009037 tyrosine-based site-specific recombinase activity Updated DEFINITION Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.
2003-08-05 GO:0017005 3'-tyrosyl-DNA phosphodiesterase activity Updated DEFINITION Catalysis of the hydrolysis of covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I (GO:0003917) and DNA.
2003-08-05 GO:0004221 ubiquitin thiolesterase activity Updated DEFINITION Catalysis of the hydrolysis of esters formed between thiols and the C-terminal glycine residue of the polypeptide ubiquitin, and of AMP-ubiquitin.
2003-08-05 GO:0046820 4-amino-4-deoxychorismate synthase activity Updated DEFINITION Catalysis of the reaction: chorismate + glutamine = 4-amino-4-deoxychorismic acid + glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); The first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
227ms