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GO Term History: Displaying 129 audit records for all terms for the date 2003-04-12

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2003-04-12 GO:0005746 mitochondrial respiratory chain Deleted SYNONYM respiratory chain complex
2003-04-12 GO:0005751 mitochondrial respiratory chain complex IV Deleted SYNONYM cytochrome c oxidase (sensu Eukarya)
2003-04-12 GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk Added SYNONYM hydrogen-transporting ATP synthase, stator stalk (sensu Eukarya)
2003-04-12 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) Added SYNONYM proton-transporting ATP synthase complex, coupling factor F(0) (sensu Eukarya)
2003-04-12 GO:0004706 JUN kinase kinase kinase activity Added SYNONYM JNK kinase kinase activity
2003-04-12 GO:0004709 MAP kinase kinase kinase activity Added SYNONYM MEK kinase
2003-04-12 GO:0004709 MAP kinase kinase kinase activity Added SYNONYM MEKK
2003-04-12 GO:0005746 mitochondrial respiratory chain Added SYNONYM respiratory chain
2003-04-12 GO:0005747 mitochondrial respiratory chain complex I Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SYNONYM fumarate reductase complex (sensu Eukarya)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SYNONYM succinate dehydrogenase complex (sensu Eukarya)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SYNONYM succinate dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0005751 mitochondrial respiratory chain complex IV Added SYNONYM cytochrome c oxidase
2003-04-12 GO:0005753 mitochondrial proton-transporting ATP synthase complex Added SYNONYM hydrogen-translocating F-type ATPase complex (sensu Eukarya)
2003-04-12 GO:0005753 mitochondrial proton-transporting ATP synthase complex Added SYNONYM respiratory chain complex V (sensu Eukarya)
2003-04-12 GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core Added SYNONYM hydrogen-transporting ATP synthase, catalytic core (sensu Eukarya)
2003-04-12 GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk Added SYNONYM hydrogen-transporting ATP synthase, central stalk (sensu Eukarya)
2003-04-12 GO:0007256 activation of JNKK activity Added SYNONYM activation of JUN kinase kinase
2003-04-12 GO:0007257 activation of JUN kinase activity Added SYNONYM activation of JUN kinase
2003-04-12 GO:0016469 proton-transporting two-sector ATPase complex Added SYNONYM hydrogen-transporting two-sector ATPase complex
2003-04-12 GO:0030061 mitochondrial crista Added SYNONYM mitochondrial cristae
2003-04-12 GO:0005747 mitochondrial respiratory chain complex I Added SECONDARY GO:0005748 (NADH dehydrogenase complex (ubiquinone) (sensu Eukarya))
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0030390 (fumarate reductase complex)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0019738 (fumarate reductase complex (sensu Eukarya))
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0009362 (succinate dehydrogenase complex (ubiquinone) (sensu Eukarya))
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0008136 (succinate dehydrogenase complex (sensu Eukarya))
2003-04-12 GO:0005753 mitochondrial proton-transporting ATP synthase complex Added SECONDARY GO:0016470 (hydrogen-translocating F-type ATPase complex (sensu Eukarya))
2003-04-12 GO:0019738 fumarate reductase complex (sensu Eukarya) Deleted SECONDARY GO:0030390 (fumarate reductase complex)
2003-04-12 GO:0019566 arabinose metabolic process Updated DEFINITION The chemical reactions and physical changes involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides and so on. D-arabinose is a constituent of arabinonucleosides.
2003-04-12 GO:0015751 arabinose transport Updated DEFINITION The directed movement of arabinose into, out of, within or between cells. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides and so on. D-arabinose is a constituent of arabinonucleosides.
2003-04-12 GO:0015147 L-arabinose transmembrane transporter activity Updated DEFINITION Enables the directed movement of arabinose into, out of, within or between cells. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, and so on.
2003-04-12 GO:0008794 arsenate reductase (glutaredoxin) activity Updated DEFINITION Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is [ NADPH -> glutathione reductase (EC:1.6.4.2) -> ] glutathione -> glutaredoxin -> arsenate reductase, i. e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.
2003-04-12 GO:0042623 ATPase activity, coupled Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane.
2003-04-12 GO:0016169 bacteriochlorophyll c binding Updated DEFINITION Interacting selectively with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.
2003-04-12 GO:0016840 carbon-nitrogen lyase activity Updated DEFINITION The carbon-nitrogen lyases are enzymes that release ammonia or one of its derivatives, with the formation of a double bond or ring. Some catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
2003-04-12 GO:0016838 carbon-oxygen lyase activity, acting on phosphates Updated DEFINITION Enzymes of sub-subclass EC:4.2.3 are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of a phosphate.
2003-04-12 GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides Updated DEFINITION Enzymes of sub-subclass EC:4.2.2 are lyases that catalyze the breakage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
2003-04-12 GO:0015515 citrate:succinate antiporter activity Updated DEFINITION Catalysis of the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).
2003-04-12 GO:0006972 hyperosmotic response Updated DEFINITION A change in state or activity of an organism or cell (in terms of movement, secretion, enzyme production, gene expression etc.) as a result of the perception of a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
2003-04-12 GO:0042430 indole-containing compound metabolic process Updated DEFINITION The chemical reactions and physical changes involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan) formed in degradation of tryptophan.
2003-04-12 GO:0042432 indole biosynthetic process Updated DEFINITION The formation from simpler components of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
2003-04-12 GO:0042433 indole catabolic process Updated DEFINITION The breakdown into simpler components of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
2003-04-12 GO:0042431 indole metabolic process Updated DEFINITION The chemical reactions and physical changes involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
2003-04-12 GO:0004706 JUN kinase kinase kinase activity Added DEFINITION Catalysis of the phosphorylation and activation of JUN kinase kinases (JNKKs).
2003-04-12 GO:0007254 JNK cascade Added DEFINITION A cascade of protein kinase activities, culminating in the phosphorylation and activation of a JUN kinase, a member of a sub-family of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
2003-04-12 GO:0004705 JUN kinase activity Added DEFINITION Catalysis of the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.
2003-04-12 GO:0042354 L-fucose metabolic process Updated DEFINITION The chemical reactions and physical changes involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.
2003-04-12 GO:0002119 nematode larval development Updated DEFINITION Development from the newly hatched first-stage larva to the end of the last larval stage (e.g. fourth-stage in C. elegans) before molting to adulthood.
2003-04-12 GO:0010010 lysine-ketoglutarate reductase activity Updated DEFINITION Catalysis of the reaction: N6-(L-1,3-dicarboxypropyl)L-lysine + NADP + H2O = L-lysine + 2-oxoglutarate + NADPH2.
2003-04-12 GO:0046911 metal chelating activity Added DEFINITION The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.
2003-04-12 GO:0004222 metalloendopeptidase activity Updated DEFINITION Enzymes within subclass EC:3.4, peptide hydrolases, that hydrolyze nonterminal peptide linkages in oligopeptides or polypeptides, and that contain a chelated metal ion as an essential catalytic activity at their active sites.
2003-04-12 GO:0030106 MHC class I receptor activity Updated DEFINITION A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells).
2003-04-12 GO:0048029 monosaccharide binding Added DEFINITION Interacting selectively with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
2003-04-12 GO:0008130 neutrophil collagenase activity Updated DEFINITION Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.
2003-04-12 GO:0016845 other carbon-nitrogen lyase activity Updated DEFINITION These enzymes of sub class EC:4.3.99 are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.
2003-04-12 GO:0016839 other carbon-oxygen lyase activity Updated DEFINITION These enzymes of sub class EC:4.2.99 are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.
2003-04-12 GO:0018376 peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine Updated DEFINITION The post-translational hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16) (GO:0004597).
2003-04-12 GO:0019715 peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid Updated DEFINITION The post-translational hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16) (GO:0004597).
2003-04-12 GO:0019430 removal of superoxide radicals Updated DEFINITION The processes involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to molecular oxygen (O2) and hydrogen peroxide (H2O2).
2003-04-12 GO:0045275 respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.
2003-04-12 GO:0045276 plasma membrane respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Found in bacteria.
2003-04-12 GO:0048031 trisaccharide binding Added DEFINITION Interacting selectively with any trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.
2003-04-12 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) Added SYNONYM proton-transporting ATP synthase complex, coupling factor F(0)
2003-04-12 GO:0045264 plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) Added SYNONYM proton-transporting ATP synthase complex, coupling factor F(0) (sensu Bacteria)
2003-04-12 GO:0045266 plasma membrane proton-transporting ATP synthase, stator stalk Added SYNONYM hydrogen-transporting ATP synthase, stator stalk (sensu Bacteria)
2003-04-12 GO:0045268 plasma membrane proton-transporting ATP synthase, catalytic core Added SYNONYM hydrogen-transporting ATP synthase, catalytic core (sensu Bacteria)
2003-04-12 GO:0045270 plasma membrane proton-transporting ATP synthase, central stalk Added SYNONYM hydrogen-transporting ATP synthase, central stalk (sensu Bacteria)
2003-04-12 GO:0046911 metal chelating activity Added SYNONYM heavy metal chelation
2003-04-12 GO:0046911 metal chelating activity Added SYNONYM metal chelation
2003-04-12 GO:0004707 MAP kinase activity Deleted SYNONYM MEK
2003-04-12 GO:0004708 MAP kinase kinase activity Deleted SYNONYM extracellular signal-regulated kinase
2003-04-12 GO:0005743 mitochondrial inner membrane Deleted SYNONYM cristae
2003-04-12 GO:0010012 steroid 22-alpha hydroxylase activity Updated DEFINITION Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.
2003-04-12 GO:0048028 galacturonan binding Added TERM galacturonan binding activity
2003-04-12 GO:0048029 monosaccharide binding Added TERM monosaccharide binding activity
2003-04-12 GO:0048030 disaccharide binding Added TERM disaccharide binding activity
2003-04-12 GO:0048031 trisaccharide binding Added TERM trisaccharide binding activity
2003-04-12 GO:0048032 galacturonate binding Added TERM galacturonate binding activity
2003-04-12 GO:0003815 complement component C1r activity Updated DEFINITION Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42).
2003-04-12 GO:0007275 multicellular organismal development Updated DEFINITION Biological processes specifically aimed at the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
2003-04-12 GO:0048030 disaccharide binding Added DEFINITION Interacting selectively with any disaccharide. Disaccharides are sugars composed of two monosaccharide units.
2003-04-12 GO:0006281 DNA repair Updated DEFINITION The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
2003-04-12 GO:0003899 DNA-directed RNA polymerase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-04-12 GO:0004175 endopeptidase activity Updated DEFINITION Any enzyme within subclass EC:3.4, peptide hydrolases, that hydrolyzes nonterminal peptide linkages in oligopeptides or polypeptides, and comprising any enzyme of sub-subclasses EC:3.4.21-99. They are classfied according to the presence of essential catalytic residues or ions at their active sites.
2003-04-12 GO:0045021 error-free DNA repair Updated DEFINITION DNA repair pathways that do not increase the mutation rate above spontaneous background levels, e.g. excision and recombination pathways.
2003-04-12 GO:0006887 exocytosis Updated DEFINITION The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.
2003-04-12 GO:0009922 fatty acid elongase activity Updated DEFINITION Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C).
2003-04-12 GO:0048028 galacturonan binding Added DEFINITION Interacting selectively with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues; a specific type of glycuronan, and a constituent of some pectins.
2003-04-12 GO:0048032 galacturonate binding Added DEFINITION Interacting selectively with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
2003-04-12 GO:0008871 aminoglycoside 2''-nucleotidyltransferase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + gentamicin = diphosphate + 2''-nucleotidylgentamicin.
2003-04-12 GO:0018467 formaldehyde dehydrogenase activity Updated DEFINITION Catalysis of the reaction: formaldehyde + NAD+ + H2O = formate + NADH + H+. Unlike EC:1.2.1.1 formaldehyde dehydrogenase (glutathione), this enzyme does not need reduced glutathione.
2003-04-12 GO:0042142 heavy metal chelation Updated DEFINITION OBSOLETE. The strong but reversible binding of a heavy metal ion by a larger molecule such as protein.
2003-04-12 GO:0016836 hydro-lyase activity Updated DEFINITION The hydro-lyases (EC:4.2.1) are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of water.
2003-04-12 GO:0008136 succinate dehydrogenase complex (sensu Eukarya) Deleted DEFINITION A multimeric complex which consists of flavoprotein (subunit A ; INTERPRO:003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; INTERPRO:000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Found in eukaryotes.
2003-04-12 GO:0009362 succinate dehydrogenase complex (ubiquinone) (sensu Eukarya) Deleted DEFINITION The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. Found in eukaryotes.
2003-04-12 GO:0019738 fumarate reductase complex (sensu Eukarya) Deleted DEFINITION A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (INTERPRO:003510; INTERPRO:004224) and D (INTERPRO:003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone); GO:0008177; GO:0008136). Found in eukaryotes.
2003-04-12 GO:0007257 activation of JUN kinase activity Added DEFINITION Upregulation of a JUN kinase activity due to phosphorylation by a JUN kinase kinase (JNKK).
2003-04-12 GO:0007256 activation of JNKK activity Added DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a sub-family of mitogen activated protein (MAP) kinases.
2003-04-12 GO:0042121 alginic acid biosynthetic process Updated DEFINITION The formation from simpler components of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
2003-04-12 GO:0042122 alginic acid catabolic process Updated DEFINITION The breakdown into simpler components of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
2003-04-12 GO:0042120 alginic acid metabolic process Updated DEFINITION The chemical reactions and physical changes involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
2003-04-12 GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk Updated TERM proton-transporting ATP synthase, stator stalk (sensu Eukarya)
2003-04-12 GO:0007256 activation of JNKK activity Updated TERM activation of JUNKK
2003-04-12 GO:0007257 activation of JUN kinase activity Updated TERM activation of JUNK
2003-04-12 GO:0005746 mitochondrial respiratory chain Updated TERM mitochondrial electron transport chain
2003-04-12 GO:0005748 NADH dehydrogenase complex (ubiquinone) (sensu Eukarya) Deleted TERM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core Updated TERM proton-transporting ATP synthase, catalytic core (sensu Eukarya)
2003-04-12 GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk Updated TERM proton-transporting ATP synthase, central stalk (sensu Eukarya)
2003-04-12 GO:0004706 JUN kinase kinase kinase activity Updated TERM JN kinase kinase kinase activity
2003-04-12 GO:0009492 2Fe-2S electron transfer carrier Updated TERM 2Fe-2S electron transfer carrier
2003-04-12 GO:0009495 thioredoxin-like 2Fe-2S ferredoxin Updated TERM thioredoxin-like 2Fe-2S ferredoxin
2003-04-12 GO:0009497 3Fe-4S/4Fe-4S electron transfer carrier Updated TERM 3Fe-4S/4Fe-4S electron transfer carrier
2003-04-12 GO:0009362 succinate dehydrogenase complex (ubiquinone) (sensu Eukarya) Deleted TERM succinate dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0008136 succinate dehydrogenase complex (sensu Eukarya) Deleted TERM succinate dehydrogenase complex (sensu Eukarya)
2003-04-12 GO:0019738 fumarate reductase complex (sensu Eukarya) Deleted TERM fumarate reductase complex (sensu Eukarya)
2003-04-12 GO:0016469 proton-transporting two-sector ATPase complex Updated TERM proton-transporting two-sector ATPase complex
2003-04-12 GO:0016470 hydrogen-translocating F-type ATPase complex (sensu Eukarya) Deleted TERM hydrogen-translocating F-type ATPase complex (sensu Eukarya)
2003-04-12 GO:0042652 mitochondrial respiratory chain complex I, peripheral segment Added TERM respiratory chain complex I, peripheral segment (sensu Eukarya)
2003-04-12 GO:0042653 mitochondrial respiratory chain complex I, membrane segment Added TERM respiratory chain complex I, membrane segment (sensu Eukarya)
2003-04-12 GO:0046911 metal chelating activity Added TERM metal chelating activity
2003-04-12 GO:0045266 plasma membrane proton-transporting ATP synthase, stator stalk Updated TERM proton-transporting ATP synthase, stator stalk (sensu Bacteria)
2003-04-12 GO:0045268 plasma membrane proton-transporting ATP synthase, catalytic core Updated TERM proton-transporting ATP synthase, catalytic core (sensu Bacteria)
2003-04-12 GO:0045270 plasma membrane proton-transporting ATP synthase, central stalk Updated TERM proton-transporting ATP synthase, central stalk (sensu Bacteria)
2003-04-12 GO:0005529 sugar binding Updated DEFINITION Interacting selectively with any any mono-, di- or trisaccharide carbohydrate.
2003-04-12 GO:0030401 transcription antiterminator activity Updated DEFINITION Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed.
2003-04-12 GO:0005750 mitochondrial respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Found in eukaryotes.
2003-04-12 GO:0046678 response to bacteriocin Updated DEFINITION A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression etc.) as a result of exposure to any bacteriocin, a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.
2003-04-12 GO:0016987 sigma factor activity Updated DEFINITION A sigma factor is the promoter specificity subunit of eubacterial-type multisubunit RNA polymerases, those whose core subunit composition is often described as alpha(2)-beta-beta-prime. (This type of multisubunit RNA polymerase complex is known to be found in eubacteria and plant plastids). Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, this binds specifically to promoter sequences, with the sigma factor making sequence specific contacts with the promotor elements. The sigma subunit is released from the elongating form of the polymerase and is thus free to act catalytically for multiple RNA polymerase core enzymes.
2003-04-12 GO:0030532 small nuclear ribonucleoprotein complex Updated DEFINITION Any of various particulate complexes of proteins with molecules of small nuclear RNA (snRNA), found in the eukaryotic nucleus; the particles are 250 kDa. They are named according to the snRNAs they contain: the U4/U6 snRNP, e.g. contains U4 and U6 snRNA. They are involved in RNA splicing (see spliceosome). Patients with systemic lupus erythematosus make antibodies directed against one or more snRNPs.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2003-04-12 GO:0048028 galacturonan binding Added TERM galacturonan binding activity
2003-04-12 GO:0048029 monosaccharide binding Added TERM monosaccharide binding activity
2003-04-12 GO:0048030 disaccharide binding Added TERM disaccharide binding activity
2003-04-12 GO:0048031 trisaccharide binding Added TERM trisaccharide binding activity
2003-04-12 GO:0048032 galacturonate binding Added TERM galacturonate binding activity
2003-04-12 GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk Updated TERM proton-transporting ATP synthase, stator stalk (sensu Eukarya)
2003-04-12 GO:0007256 activation of JNKK activity Updated TERM activation of JUNKK
2003-04-12 GO:0007257 activation of JUN kinase activity Updated TERM activation of JUNK
2003-04-12 GO:0005746 mitochondrial respiratory chain Updated TERM mitochondrial electron transport chain
2003-04-12 GO:0005748 NADH dehydrogenase complex (ubiquinone) (sensu Eukarya) Deleted TERM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core Updated TERM proton-transporting ATP synthase, catalytic core (sensu Eukarya)
2003-04-12 GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk Updated TERM proton-transporting ATP synthase, central stalk (sensu Eukarya)
2003-04-12 GO:0004706 JUN kinase kinase kinase activity Updated TERM JN kinase kinase kinase activity
2003-04-12 GO:0009492 2Fe-2S electron transfer carrier Updated TERM 2Fe-2S electron transfer carrier
2003-04-12 GO:0009495 thioredoxin-like 2Fe-2S ferredoxin Updated TERM thioredoxin-like 2Fe-2S ferredoxin
2003-04-12 GO:0009497 3Fe-4S/4Fe-4S electron transfer carrier Updated TERM 3Fe-4S/4Fe-4S electron transfer carrier
2003-04-12 GO:0009362 succinate dehydrogenase complex (ubiquinone) (sensu Eukarya) Deleted TERM succinate dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0008136 succinate dehydrogenase complex (sensu Eukarya) Deleted TERM succinate dehydrogenase complex (sensu Eukarya)
2003-04-12 GO:0019738 fumarate reductase complex (sensu Eukarya) Deleted TERM fumarate reductase complex (sensu Eukarya)
2003-04-12 GO:0016469 proton-transporting two-sector ATPase complex Updated TERM proton-transporting two-sector ATPase complex
2003-04-12 GO:0016470 hydrogen-translocating F-type ATPase complex (sensu Eukarya) Deleted TERM hydrogen-translocating F-type ATPase complex (sensu Eukarya)
2003-04-12 GO:0042652 mitochondrial respiratory chain complex I, peripheral segment Added TERM respiratory chain complex I, peripheral segment (sensu Eukarya)
2003-04-12 GO:0042653 mitochondrial respiratory chain complex I, membrane segment Added TERM respiratory chain complex I, membrane segment (sensu Eukarya)
2003-04-12 GO:0046911 metal chelating activity Added TERM metal chelating activity
2003-04-12 GO:0045266 plasma membrane proton-transporting ATP synthase, stator stalk Updated TERM proton-transporting ATP synthase, stator stalk (sensu Bacteria)
2003-04-12 GO:0045268 plasma membrane proton-transporting ATP synthase, catalytic core Updated TERM proton-transporting ATP synthase, catalytic core (sensu Bacteria)
2003-04-12 GO:0045270 plasma membrane proton-transporting ATP synthase, central stalk Updated TERM proton-transporting ATP synthase, central stalk (sensu Bacteria)

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2003-04-12 GO:0005746 mitochondrial respiratory chain Deleted SYNONYM respiratory chain complex
2003-04-12 GO:0005751 mitochondrial respiratory chain complex IV Deleted SYNONYM cytochrome c oxidase (sensu Eukarya)
2003-04-12 GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk Added SYNONYM hydrogen-transporting ATP synthase, stator stalk (sensu Eukarya)
2003-04-12 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) Added SYNONYM proton-transporting ATP synthase complex, coupling factor F(0) (sensu Eukarya)
2003-04-12 GO:0004706 JUN kinase kinase kinase activity Added SYNONYM JNK kinase kinase activity
2003-04-12 GO:0004709 MAP kinase kinase kinase activity Added SYNONYM MEK kinase
2003-04-12 GO:0004709 MAP kinase kinase kinase activity Added SYNONYM MEKK
2003-04-12 GO:0005746 mitochondrial respiratory chain Added SYNONYM respiratory chain
2003-04-12 GO:0005747 mitochondrial respiratory chain complex I Added SYNONYM NADH dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SYNONYM fumarate reductase complex (sensu Eukarya)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SYNONYM succinate dehydrogenase complex (sensu Eukarya)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SYNONYM succinate dehydrogenase complex (ubiquinone) (sensu Eukarya)
2003-04-12 GO:0005751 mitochondrial respiratory chain complex IV Added SYNONYM cytochrome c oxidase
2003-04-12 GO:0005753 mitochondrial proton-transporting ATP synthase complex Added SYNONYM hydrogen-translocating F-type ATPase complex (sensu Eukarya)
2003-04-12 GO:0005753 mitochondrial proton-transporting ATP synthase complex Added SYNONYM respiratory chain complex V (sensu Eukarya)
2003-04-12 GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core Added SYNONYM hydrogen-transporting ATP synthase, catalytic core (sensu Eukarya)
2003-04-12 GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk Added SYNONYM hydrogen-transporting ATP synthase, central stalk (sensu Eukarya)
2003-04-12 GO:0007256 activation of JNKK activity Added SYNONYM activation of JUN kinase kinase
2003-04-12 GO:0007257 activation of JUN kinase activity Added SYNONYM activation of JUN kinase
2003-04-12 GO:0016469 proton-transporting two-sector ATPase complex Added SYNONYM hydrogen-transporting two-sector ATPase complex
2003-04-12 GO:0030061 mitochondrial crista Added SYNONYM mitochondrial cristae
2003-04-12 GO:0019566 arabinose metabolic process Updated DEFINITION The chemical reactions and physical changes involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides and so on. D-arabinose is a constituent of arabinonucleosides.
2003-04-12 GO:0015751 arabinose transport Updated DEFINITION The directed movement of arabinose into, out of, within or between cells. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides and so on. D-arabinose is a constituent of arabinonucleosides.
2003-04-12 GO:0015147 L-arabinose transmembrane transporter activity Updated DEFINITION Enables the directed movement of arabinose into, out of, within or between cells. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, and so on.
2003-04-12 GO:0008794 arsenate reductase (glutaredoxin) activity Updated DEFINITION Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is [ NADPH -> glutathione reductase (EC:1.6.4.2) -> ] glutathione -> glutaredoxin -> arsenate reductase, i. e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.
2003-04-12 GO:0042623 ATPase activity, coupled Updated DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane.
2003-04-12 GO:0016169 bacteriochlorophyll c binding Updated DEFINITION Interacting selectively with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.
2003-04-12 GO:0016840 carbon-nitrogen lyase activity Updated DEFINITION The carbon-nitrogen lyases are enzymes that release ammonia or one of its derivatives, with the formation of a double bond or ring. Some catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
2003-04-12 GO:0016838 carbon-oxygen lyase activity, acting on phosphates Updated DEFINITION Enzymes of sub-subclass EC:4.2.3 are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of a phosphate.
2003-04-12 GO:0016837 carbon-oxygen lyase activity, acting on polysaccharides Updated DEFINITION Enzymes of sub-subclass EC:4.2.2 are lyases that catalyze the breakage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
2003-04-12 GO:0015515 citrate:succinate antiporter activity Updated DEFINITION Catalysis of the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).
2003-04-12 GO:0006972 hyperosmotic response Updated DEFINITION A change in state or activity of an organism or cell (in terms of movement, secretion, enzyme production, gene expression etc.) as a result of the perception of a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
2003-04-12 GO:0042430 indole-containing compound metabolic process Updated DEFINITION The chemical reactions and physical changes involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan) formed in degradation of tryptophan.
2003-04-12 GO:0042432 indole biosynthetic process Updated DEFINITION The formation from simpler components of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
2003-04-12 GO:0042433 indole catabolic process Updated DEFINITION The breakdown into simpler components of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
2003-04-12 GO:0042431 indole metabolic process Updated DEFINITION The chemical reactions and physical changes involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
2003-04-12 GO:0004706 JUN kinase kinase kinase activity Added DEFINITION Catalysis of the phosphorylation and activation of JUN kinase kinases (JNKKs).
2003-04-12 GO:0007254 JNK cascade Added DEFINITION A cascade of protein kinase activities, culminating in the phosphorylation and activation of a JUN kinase, a member of a sub-family of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress.
2003-04-12 GO:0004705 JUN kinase activity Added DEFINITION Catalysis of the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.
2003-04-12 GO:0042354 L-fucose metabolic process Updated DEFINITION The chemical reactions and physical changes involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.
2003-04-12 GO:0002119 nematode larval development Updated DEFINITION Development from the newly hatched first-stage larva to the end of the last larval stage (e.g. fourth-stage in C. elegans) before molting to adulthood.
2003-04-12 GO:0010010 lysine-ketoglutarate reductase activity Updated DEFINITION Catalysis of the reaction: N6-(L-1,3-dicarboxypropyl)L-lysine + NADP + H2O = L-lysine + 2-oxoglutarate + NADPH2.
2003-04-12 GO:0046911 metal chelating activity Added DEFINITION The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.
2003-04-12 GO:0004222 metalloendopeptidase activity Updated DEFINITION Enzymes within subclass EC:3.4, peptide hydrolases, that hydrolyze nonterminal peptide linkages in oligopeptides or polypeptides, and that contain a chelated metal ion as an essential catalytic activity at their active sites.
2003-04-12 GO:0030106 MHC class I receptor activity Updated DEFINITION A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells).
2003-04-12 GO:0048029 monosaccharide binding Added DEFINITION Interacting selectively with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
2003-04-12 GO:0008130 neutrophil collagenase activity Updated DEFINITION Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.
2003-04-12 GO:0016845 other carbon-nitrogen lyase activity Updated DEFINITION These enzymes of sub class EC:4.3.99 are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.
2003-04-12 GO:0016839 other carbon-oxygen lyase activity Updated DEFINITION These enzymes of sub class EC:4.2.99 are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.
2003-04-12 GO:0018376 peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine Updated DEFINITION The post-translational hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16) (GO:0004597).
2003-04-12 GO:0019715 peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid Updated DEFINITION The post-translational hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16) (GO:0004597).
2003-04-12 GO:0019430 removal of superoxide radicals Updated DEFINITION The processes involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to molecular oxygen (O2) and hydrogen peroxide (H2O2).
2003-04-12 GO:0045275 respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.
2003-04-12 GO:0045276 plasma membrane respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Found in bacteria.
2003-04-12 GO:0048031 trisaccharide binding Added DEFINITION Interacting selectively with any trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.
2003-04-12 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) Added SYNONYM proton-transporting ATP synthase complex, coupling factor F(0)
2003-04-12 GO:0045264 plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) Added SYNONYM proton-transporting ATP synthase complex, coupling factor F(0) (sensu Bacteria)
2003-04-12 GO:0045266 plasma membrane proton-transporting ATP synthase, stator stalk Added SYNONYM hydrogen-transporting ATP synthase, stator stalk (sensu Bacteria)
2003-04-12 GO:0045268 plasma membrane proton-transporting ATP synthase, catalytic core Added SYNONYM hydrogen-transporting ATP synthase, catalytic core (sensu Bacteria)
2003-04-12 GO:0045270 plasma membrane proton-transporting ATP synthase, central stalk Added SYNONYM hydrogen-transporting ATP synthase, central stalk (sensu Bacteria)
2003-04-12 GO:0046911 metal chelating activity Added SYNONYM heavy metal chelation
2003-04-12 GO:0046911 metal chelating activity Added SYNONYM metal chelation
2003-04-12 GO:0004707 MAP kinase activity Deleted SYNONYM MEK
2003-04-12 GO:0004708 MAP kinase kinase activity Deleted SYNONYM extracellular signal-regulated kinase
2003-04-12 GO:0005743 mitochondrial inner membrane Deleted SYNONYM cristae
2003-04-12 GO:0010012 steroid 22-alpha hydroxylase activity Updated DEFINITION Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.
2003-04-12 GO:0003815 complement component C1r activity Updated DEFINITION Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42).
2003-04-12 GO:0007275 multicellular organismal development Updated DEFINITION Biological processes specifically aimed at the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
2003-04-12 GO:0048030 disaccharide binding Added DEFINITION Interacting selectively with any disaccharide. Disaccharides are sugars composed of two monosaccharide units.
2003-04-12 GO:0006281 DNA repair Updated DEFINITION The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
2003-04-12 GO:0003899 DNA-directed RNA polymerase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) while utilizing a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2003-04-12 GO:0004175 endopeptidase activity Updated DEFINITION Any enzyme within subclass EC:3.4, peptide hydrolases, that hydrolyzes nonterminal peptide linkages in oligopeptides or polypeptides, and comprising any enzyme of sub-subclasses EC:3.4.21-99. They are classfied according to the presence of essential catalytic residues or ions at their active sites.
2003-04-12 GO:0045021 error-free DNA repair Updated DEFINITION DNA repair pathways that do not increase the mutation rate above spontaneous background levels, e.g. excision and recombination pathways.
2003-04-12 GO:0006887 exocytosis Updated DEFINITION The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.
2003-04-12 GO:0009922 fatty acid elongase activity Updated DEFINITION Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C).
2003-04-12 GO:0048028 galacturonan binding Added DEFINITION Interacting selectively with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues; a specific type of glycuronan, and a constituent of some pectins.
2003-04-12 GO:0048032 galacturonate binding Added DEFINITION Interacting selectively with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
2003-04-12 GO:0008871 aminoglycoside 2''-nucleotidyltransferase activity Updated DEFINITION Catalysis of the reaction: nucleoside triphosphate + gentamicin = diphosphate + 2''-nucleotidylgentamicin.
2003-04-12 GO:0018467 formaldehyde dehydrogenase activity Updated DEFINITION Catalysis of the reaction: formaldehyde + NAD+ + H2O = formate + NADH + H+. Unlike EC:1.2.1.1 formaldehyde dehydrogenase (glutathione), this enzyme does not need reduced glutathione.
2003-04-12 GO:0042142 heavy metal chelation Updated DEFINITION OBSOLETE. The strong but reversible binding of a heavy metal ion by a larger molecule such as protein.
2003-04-12 GO:0016836 hydro-lyase activity Updated DEFINITION The hydro-lyases (EC:4.2.1) are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of water.
2003-04-12 GO:0008136 succinate dehydrogenase complex (sensu Eukarya) Deleted DEFINITION A multimeric complex which consists of flavoprotein (subunit A ; INTERPRO:003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; INTERPRO:000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Found in eukaryotes.
2003-04-12 GO:0009362 succinate dehydrogenase complex (ubiquinone) (sensu Eukarya) Deleted DEFINITION The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration. Found in eukaryotes.
2003-04-12 GO:0019738 fumarate reductase complex (sensu Eukarya) Deleted DEFINITION A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (INTERPRO:003510; INTERPRO:004224) and D (INTERPRO:003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone); GO:0008177; GO:0008136). Found in eukaryotes.
2003-04-12 GO:0007257 activation of JUN kinase activity Added DEFINITION Upregulation of a JUN kinase activity due to phosphorylation by a JUN kinase kinase (JNKK).
2003-04-12 GO:0007256 activation of JNKK activity Added DEFINITION Catalysis of the phosphorylation and activation of JUN kinases (JNKs), members of a sub-family of mitogen activated protein (MAP) kinases.
2003-04-12 GO:0042121 alginic acid biosynthetic process Updated DEFINITION The formation from simpler components of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
2003-04-12 GO:0042122 alginic acid catabolic process Updated DEFINITION The breakdown into simpler components of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
2003-04-12 GO:0042120 alginic acid metabolic process Updated DEFINITION The chemical reactions and physical changes involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
2003-04-12 GO:0005529 sugar binding Updated DEFINITION Interacting selectively with any any mono-, di- or trisaccharide carbohydrate.
2003-04-12 GO:0030401 transcription antiterminator activity Updated DEFINITION Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed.
2003-04-12 GO:0005750 mitochondrial respiratory chain complex III Updated DEFINITION A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Found in eukaryotes.
2003-04-12 GO:0046678 response to bacteriocin Updated DEFINITION A change in state or activity of the organism (in terms of movement, secretion, enzyme production, gene expression etc.) as a result of exposure to any bacteriocin, a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.
2003-04-12 GO:0016987 sigma factor activity Updated DEFINITION A sigma factor is the promoter specificity subunit of eubacterial-type multisubunit RNA polymerases, those whose core subunit composition is often described as alpha(2)-beta-beta-prime. (This type of multisubunit RNA polymerase complex is known to be found in eubacteria and plant plastids). Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, this binds specifically to promoter sequences, with the sigma factor making sequence specific contacts with the promotor elements. The sigma subunit is released from the elongating form of the polymerase and is thus free to act catalytically for multiple RNA polymerase core enzymes.
2003-04-12 GO:0030532 small nuclear ribonucleoprotein complex Updated DEFINITION Any of various particulate complexes of proteins with molecules of small nuclear RNA (snRNA), found in the eukaryotic nucleus; the particles are 250 kDa. They are named according to the snRNAs they contain: the U4/U6 snRNP, e.g. contains U4 and U6 snRNA. They are involved in RNA splicing (see spliceosome). Patients with systemic lupus erythematosus make antibodies directed against one or more snRNPs.

Other

Timestamp GO ID GO Term Name Action Category Detail
2003-04-12 GO:0005747 mitochondrial respiratory chain complex I Added SECONDARY GO:0005748 (NADH dehydrogenase complex (ubiquinone) (sensu Eukarya))
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0030390 (fumarate reductase complex)
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0019738 (fumarate reductase complex (sensu Eukarya))
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0009362 (succinate dehydrogenase complex (ubiquinone) (sensu Eukarya))
2003-04-12 GO:0005749 mitochondrial respiratory chain complex II Added SECONDARY GO:0008136 (succinate dehydrogenase complex (sensu Eukarya))
2003-04-12 GO:0005753 mitochondrial proton-transporting ATP synthase complex Added SECONDARY GO:0016470 (hydrogen-translocating F-type ATPase complex (sensu Eukarya))
2003-04-12 GO:0019738 fumarate reductase complex (sensu Eukarya) Deleted SECONDARY GO:0030390 (fumarate reductase complex)
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