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GO Term History: Displaying 500 audit records for all terms for the date 2002-11-27

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Introduction

This page displays the differences recorded in the full Gene Ontology OBO v1.2 file as audited by the UniProt-GOA database during its daily update cycle.
If there is any delay in uploading the current OBO file, the changes displayed and the date recorded for these changes may not correspond to when the changes to the OBO file were committed.

All changes

Timestamp GO ID GO Term Name Action Category Detail
2002-11-27 GO:0019005 SCF ubiquitin ligase complex Updated TERM SCF ubiquitin ligase complex
2002-11-27 GO:0017133 mitochondrial electron transfer flavoprotein complex Updated TERM electron transfer flavoprotein complex (sensu Eukarya)
2002-11-27 GO:0045247 cytosolic electron transfer flavoprotein complex Updated TERM electron transfer flavoprotein complex (sensu Bacteria)
2002-11-27 GO:0046716 muscle cell cellular homeostasis Added TERM muscle maintenance
2002-11-27 GO:0046717 acid secretion Added TERM acid secretion
2002-11-27 GO:0018879 biphenyl metabolic process Added DEFINITION The chemical reactions and physical changes involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
2002-11-27 GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity Added DEFINITION Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.
2002-11-27 GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-guanosyl)tetraphosphate + H2O = GTP + GMP. Also acts on bis(5'-xanthosyl)-tetraphosphate and, more slowly, on bis(5'-adenosyl)-tetraphosphate and bis(5'-uridyl)-tetraphosphate.
2002-11-27 GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl)tetraphosphate + H2O = 2 ADP.
2002-11-27 GO:0004082 bisphosphoglycerate mutase activity Added DEFINITION Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.
2002-11-27 GO:0004083 bisphosphoglycerate 2-phosphatase activity Added DEFINITION Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 3-phosphoglycerate + phosphate.
2002-11-27 GO:0018750 biuret amidohydrolase activity Added DEFINITION Catalysis of the reaction: biuret + H2O = urea + carbon dioxide + ammonia.
2002-11-27 GO:0007350 blastoderm segmentation Added DEFINITION The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.
2002-11-27 GO:0008423 bleomycin hydrolase activity Added DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2002-11-27 GO:0007596 blood coagulation Added DEFINITION The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
2002-11-27 GO:0003803 coagulation factor IXa activity Added DEFINITION Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa.
2002-11-27 GO:0003802 coagulation factor VIIa activity Added DEFINITION Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa.
2002-11-27 GO:0003804 coagulation factor Xa activity Added DEFINITION Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin.
2002-11-27 GO:0003805 coagulation factor XIa activity Added DEFINITION Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa.
2002-11-27 GO:0003806 coagulation factor XIIa activity Added DEFINITION Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.
2002-11-27 GO:0007598 blood coagulation, extrinsic pathway Added DEFINITION A pathway of blood coagulation in which the earlier stages of the cascade are bypassed and the activation of factor X to factor Xa is effected by the combination of factor VIIa + thromboplastin; this second pathway occurs when tissue extracts are present in optimal amounts and is much more rapid than the intrinsic pathway (Compare blood coagulation, intrinsic pathway GO:0007597).
2002-11-27 GO:0007597 blood coagulation, intrinsic pathway Added DEFINITION A pathway of blood coagulation that occurs during the clotting of platelet-poor plasma, in which activation of factor X to factor Xa is effected by the combination of factor IXa + factor VIIIa + calcium ion + phospholipid.
2002-11-27 GO:0005555 blood group antigen Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0001568 blood vessel development Added DEFINITION Development of vasculature carrying blood.
2002-11-27 GO:0045431 flavonol synthase activity Added DEFINITION Catalysis of the alpha-ketoglutarate-dependent oxidation of dihydroflavonols to flavonols.
2002-11-27 GO:0000128 flocculation Added DEFINITION Non-sexual aggregation of single-celled organisms in culture.
2002-11-27 GO:0000501 flocculation via cell wall protein-carbohydrate interaction Added DEFINITION Mannose sensitive, non sexual aggregation of cells mediated by protein-carbohydrate (flocculin-mannan) interaction present in the cell wall. This process is pH and calcium dependent and reversible.
2002-11-27 GO:0009908 flower development Added DEFINITION The development of reproductive structures in a plant beginning with the transition of the vegetative shoot apex into a reproductive apex.
2002-11-27 GO:0046234 fluorene biosynthetic process Added DEFINITION OBSOLETE. The synthesis from simpler components of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
2002-11-27 GO:0019429 fluorene catabolic process Added DEFINITION The breakdown into simpler components of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
2002-11-27 GO:0018917 fluorene metabolic process Added DEFINITION The chemical reactions and physical changes involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
2002-11-27 GO:0003919 FMN adenylyltransferase activity Added DEFINITION Catalysis of the reaction: ATP + FMN = diphosphate + FAD.
2002-11-27 GO:0009398 FMN biosynthetic process Added DEFINITION The formation from simpler components of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
2002-11-27 GO:0046444 FMN metabolic process Added DEFINITION The chemical reactions and physical changes involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
2002-11-27 GO:0009396 folic acid-containing compound biosynthetic process Added DEFINITION The formation from simpler components of folic acid and its derivatives.
2002-11-27 GO:0005794 Golgi apparatus Added DEFINITION A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2002-11-27 GO:0005801 cis-Golgi network Added DEFINITION The convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
2002-11-27 GO:0000139 Golgi membrane Added DEFINITION The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
2002-11-27 GO:0030173 integral component of Golgi membrane Added DEFINITION An integral membrane protein found in membranes of the Golgi complex.
2002-11-27 GO:0007030 Golgi organization Added DEFINITION Assembly and maintenance of the Golgi apparatus.
2002-11-27 GO:0045053 protein retention in Golgi apparatus Added DEFINITION The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.
2002-11-27 GO:0006895 Golgi to endosome transport Added DEFINITION The directed movement of proteins from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
2002-11-27 GO:0006893 Golgi to plasma membrane transport Added DEFINITION The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
2002-11-27 GO:0006894 Golgi to secretory vesicle transport Added DEFINITION The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release.
2002-11-27 GO:0006896 Golgi to vacuole transport Added DEFINITION The directed movement of proteins from the Golgi to the vacuole.
2002-11-27 GO:0005802 trans-Golgi network Added DEFINITION The concave side of the Golgi apparatus, from which secretory vesicles emerge.
2002-11-27 GO:0017119 Golgi transport complex Updated DEFINITION A complex of proteins that, in vitro, stimulates intra-Golgi transport; a 13S complex, about 800 kDa in size and consists of at least five polypeptides. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p).
2002-11-27 GO:0005798 Golgi-associated vesicle Added DEFINITION Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
2002-11-27 GO:0030142 Golgi to ER transport vesicle Added DEFINITION A vesicle that mediates transport from the Golgi to the endoplasmic reticulum.
2002-11-27 GO:0012508 Golgi to ER transport vesicle membrane Added DEFINITION The membrane surrounding a vesicle transporting substances from the Golgi to the ER.
2002-11-27 GO:0005808 Golgi-plasma membrane transport vesicle Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0005809 Golgi-vacuole transport vesicle Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0008406 gonad development Added DEFINITION The development of an animal organ that produces gametes; in some species it also produces hormones.
2002-11-27 GO:0004898 gp130 Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0006506 GPI anchor biosynthetic process Added DEFINITION The formation from simpler components of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2002-11-27 GO:0018270 GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018265 GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018266 GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018267 GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018268 GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018269 GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0006505 GPI anchor metabolic process Updated DEFINITION The chemical reactions and physical changes involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate moiety, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
2002-11-27 GO:0042080 GPI/GSI anchor biosynthetic process Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0019985 translesion synthesis Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is mutagenic.
2002-11-27 GO:0000251 C-14 sterol reductase activity Updated DEFINITION Catalysis of the reduction of the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol.
2002-11-27 GO:0000249 C-22 sterol desaturase activity Updated DEFINITION Catalysis of the formation of the C-22(23) double bond in the sterol side chain.
2002-11-27 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity Updated DEFINITION Catalysis of the removal of the 3-alpha hydrogen from the 3-ketocarboxylic acid sterol intermediate, resulting in the decarboxylation of the 3-ketocarboxylic acid: acts in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol in ergosterol biosynthesis.
2002-11-27 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity Added DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + carbon dioxide + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2002-11-27 GO:0005951 carbamoyl-phosphate synthase complex Added DEFINITION An enzyme complex that exists in monomer, dimer, and higher oligomeric forms. Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.
2002-11-27 GO:0046231 carbazole biosynthetic process Added DEFINITION OBSOLETE. The formation from simpler components of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
2002-11-27 GO:0046232 carbazole catabolic process Added DEFINITION The breakdown into simpler components of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
2002-11-27 GO:0006458 'de novo' protein folding Added DEFINITION Processes that assist the folding of a nascent peptide chain into its correct tertiary structure.
2002-11-27 GO:0046211 (+)-camphor biosynthetic process Added DEFINITION The formation from simpler components of (+)-camphor, a bicyclic monoterpene ketone.
2002-11-27 GO:0019383 (+)-camphor catabolic process Added DEFINITION The breakdown into simpler components of (+)-camphor, a bicyclic monoterpene ketone.
2002-11-27 GO:0018882 (+)-camphor metabolic process Added DEFINITION The chemical reactions and physical changes involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.
2002-11-27 GO:0046550 (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine Added DEFINITION The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7.
2002-11-27 GO:0019084 middle viral transcription Added DEFINITION The second round of viral gene transcription; most genes transcribed in this round are necessary for genome replication.
2002-11-27 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide.
2002-11-27 GO:0019599 (R)-4-hydroxymandelate catabolic process Added DEFINITION The breakdown into simpler components of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.
2002-11-27 GO:0046431 (R)-4-hydroxymandelate metabolic process Added DEFINITION The chemical reactions and physical changes involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).
2002-11-27 GO:0019147 (R)-aminopropanol dehydrogenase activity Added DEFINITION Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + NADH + H+.
2002-11-27 GO:0015746 citrate transport Added DEFINITION Directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, outside, or within a cell.
2002-11-27 GO:0015137 citrate transmembrane transporter activity Added DEFINITION Enables the directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, outside, or within a cell.
2002-11-27 GO:0019240 citrulline biosynthetic process Added DEFINITION The formation from simpler components of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
2002-11-27 GO:0019241 citrulline catabolic process Added DEFINITION The breakdown into simpler components of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
2002-11-27 GO:0000052 citrulline metabolic process Added DEFINITION The chemical reactions and physical changes involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
2002-11-27 GO:0008816 citryl-CoA lyase activity Added DEFINITION Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.
2002-11-27 GO:0001620 class A orphan receptor activity Added DEFINITION A G-protein coupled receptor that is structurally and functionally related to the rhodopsin receptor, but whose ligand is unknown.
2002-11-27 GO:0001645 class C orphan receptor activity Added DEFINITION A G-protein coupled receptor that is structurally/functionally related to the metabotropic glutamate receptors and binds an unknown ligand.
2002-11-27 GO:0009466 class I cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0003820 class I major histocompatibility complex antigen Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009469 class II cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0003821 class II major histocompatibility complex antigen Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009470 class IIa cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009480 class IIb cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009471 class III cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009476 class IV cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0003813 classical-complement-pathway C3/C5 convertase activity Added DEFINITION Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b.
2002-11-27 GO:0005906 clathrin adaptor Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0030131 clathrin adaptor complex Added DEFINITION A membrane adaptor complex that links clathrin to a membrane.
2002-11-27 GO:0030118 clathrin coat Added DEFINITION A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.
2002-11-27 GO:0030132 clathrin coat of coated pit Added DEFINITION The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.
2002-11-27 GO:0030128 clathrin coat of endocytic vesicle Added DEFINITION A clathrin coat found on an endocytic vesicle.
2002-11-27 GO:0030129 clathrin coat of synaptic vesicle Added DEFINITION A clathrin coat found on a synaptic vesicle.
2002-11-27 GO:0030130 clathrin coat of trans-Golgi network vesicle Added DEFINITION A clathrin coat found on a vesicle of the trans-Golgi network.
2002-11-27 GO:0030125 clathrin vesicle coat Added DEFINITION A clathrin coat found on a vesicle.
2002-11-27 GO:0045334 clathrin-coated endocytic vesicle Added DEFINITION A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.
2002-11-27 GO:0045336 clathrin-coated phagocytic vesicle Added DEFINITION A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
2002-11-27 GO:0030136 clathrin-coated vesicle Added DEFINITION A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
2002-11-27 GO:0030365 cleavage stimulation factor activity Added DEFINITION A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide.
2002-11-27 GO:0030364 cleavage and polyadenylylation specificity factor activity Added DEFINITION A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions.
2002-11-27 GO:0045163 clustering of voltage-gated potassium channels Added DEFINITION The process by which voltage gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.
2002-11-27 GO:0018252 peptide cross-linking via L-seryl-5-imidazolinone glycine Added DEFINITION The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue N, a serine, to the alpha-amino nitrogen of residue N+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue N+1. This cross-linking is coupled with a dehydrogenation of residue N+1 to form a double bond between the alpha and beta carbons. See GO:0018251.
2002-11-27 GO:0009374 biotin binding Added DEFINITION Interacting selectively and stoichiometrically with biotin (cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2002-11-27 GO:0009102 biotin biosynthetic process Added DEFINITION The formation from simpler components of biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid.
2002-11-27 GO:0004075 biotin carboxylase activity Added DEFINITION Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + carbon dioxide = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
2002-11-27 GO:0009343 biotin carboxylase complex Added DEFINITION An enzyme that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide.
2002-11-27 GO:0042367 biotin catabolic process Added DEFINITION The breakdown into simpler components of biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid.
2002-11-27 GO:0006768 biotin metabolic process Added DEFINITION The chemical reactions and physical changes involving biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2002-11-27 GO:0004076 biotin synthase activity Added DEFINITION Catalysis of the reaction: dethiobiotin + sulfur = biotin.
2002-11-27 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP forming)] = AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase (ADP forming)].
2002-11-27 GO:0004078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)].
2002-11-27 GO:0004079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[methylmalonyl-CoA:pyruvate carboxyltransferase] = AMP + diphosphate + [methylmalonyl-CoA:pyruvate carboxyltransferase].
2002-11-27 GO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)].
2002-11-27 GO:0019018 bipartite viral genome Added DEFINITION A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.
2002-11-27 GO:0018687 biphenyl 2,3-dioxygenase activity Added DEFINITION Catalysis of the conversion of biphenyl to (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol with the oxidation of NADH to NAD; requires Fe[2+].
2002-11-27 GO:0000286 alanine dehydrogenase activity Added DEFINITION Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + ammonia + NADH + H+.
2002-11-27 GO:0006522 alanine metabolic process Added DEFINITION The chemical reactions and physical changes involving alanine, 2-aminopropanoic acid.
2002-11-27 GO:0008784 alanine racemase activity Added DEFINITION Catalysis of the reaction: L-alanine = D-alanine.
2002-11-27 GO:0018086 alanine racemization Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0015808 L-alanine transport Added DEFINITION The directed movement of alanine, 2-aminopropanoic acid, into, out of, or within a cell.
2002-11-27 GO:0015180 L-alanine transmembrane transporter activity Added DEFINITION Enables the directed movement of alanine, 2-aminopropanoic acid, into, out of, or within a cell.
2002-11-27 GO:0008453 alanine-glyoxylate transaminase activity Added DEFINITION Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.
2002-11-27 GO:0045107 intermediate filament polymerization Added DEFINITION Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.
2002-11-27 GO:0045105 intermediate filament polymerization or depolymerization Added DEFINITION Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.
2002-11-27 GO:0045103 intermediate filament-based process Added DEFINITION Any cellular process that depends upon or alters the intermediate filament cytoskeleton (that part of the cytoskeleton comprising intermediate filaments and their associated proteins).
2002-11-27 GO:0009898 cytoplasmic side of plasma membrane Added DEFINITION The side of the plasma membrane that faces the cytoplasm.
2002-11-27 GO:0005707 interphase chromosome Added DEFINITION A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently.
2002-11-27 GO:0001560 regulation of cell growth by extracellular stimulus Updated DEFINITION The process where external signals regulate whether a cell increases its mass (size).
2002-11-27 GO:0001559 regulation of cell growth by detection of nuclear:cytoplasmic ratio Updated DEFINITION The process where the size of the nucleus with respect to its cytoplasm signals the cell to grow or stop growing.
2002-11-27 GO:0004232 interstitial collagenase activity Added DEFINITION Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.
2002-11-27 GO:0006891 intra-Golgi vesicle-mediated transport Added DEFINITION The directed movement of proteins within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).
2002-11-27 GO:0005622 intracellular Added DEFINITION The living contents of a cell; the matter contained within the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
2002-11-27 GO:0006973 intracellular accumulation of glycerol Added DEFINITION The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the perception of a hyperosmotic environment.
2002-11-27 GO:0046691 intracellular canaliculus Added DEFINITION A narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates.
2002-11-27 GO:0006886 intracellular protein transport Updated DEFINITION The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
2002-11-27 GO:0030522 intracellular receptor signaling pathway Added DEFINITION A signaling pathway initiated by a ligand entering the target cell, where it binds to an intracellular receptor.
2002-11-27 GO:0005241 inward rectifier channel Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0004447 iodide peroxidase activity Added DEFINITION Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O.
2002-11-27 GO:0015705 iodide transport Added DEFINITION Directed movement of iodide into, outside, or within a cell.
2002-11-27 GO:0005216 ion channel activity Added DEFINITION Allows the regulatable energy-independent passage of ions across a lipid bilayer down a concentration gradient.
2002-11-27 GO:0045161 neuronal ion channel clustering Added DEFINITION The process by which voltage-gated sodium and potassium become localized to distinct subcellular domains. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
2002-11-27 GO:0015075 ion transmembrane transporter activity Added DEFINITION Enables the directed movement of charged atoms or small charged molecules into, out of, or within a cell.
2002-11-27 GO:0018922 iprodione metabolic process Added DEFINITION The chemical reactions and physical changes involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium).
2002-11-27 GO:0018290 iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide Added DEFINITION The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.
2002-11-27 GO:0009785 blue light signaling pathway Added DEFINITION The process by which blue light is converted into a cellular response.
2002-11-27 GO:0030509 BMP signaling pathway Added DEFINITION Signaling pathway involving receptors for any of the BMP (bone morphogenetic protein) family.
2002-11-27 GO:0040032 post-embryonic body morphogenesis Added DEFINITION Formation and development of organized structures of the post-embryonic soma.
2002-11-27 GO:0030282 bone mineralization Added DEFINITION The deposition of calcium phosphate in bone tissue.
2002-11-27 GO:0045453 bone resorption Added DEFINITION The process by which bone tissue is lost; it can be through physiologic or pathologic means.
2002-11-27 GO:0046714 borate binding Added DEFINITION Interacting selectively and stoichiometrically with boron, the group 13 element with properties which are borderline between metals and non-metals.
2002-11-27 GO:0046713 borate transport Added DEFINITION The directed movement of boron into, out of, or within a cell. Boron is a group 13 element, with properties which are borderline between metals and non-metals.
2002-11-27 GO:0046715 borate transmembrane transporter activity Added DEFINITION Catalysis of the transport of boron across a membrane against the concentration gradient.
2002-11-27 GO:0005734 box C + D snoRNP protein Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0005735 box H + ACA snoRNP protein Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009082 branched-chain amino acid biosynthetic process Added DEFINITION The formation from simpler components of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2002-11-27 GO:0009083 branched-chain amino acid catabolic process Added DEFINITION The breakdown into simpler components of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2002-11-27 GO:0009081 branched-chain amino acid metabolic process Added DEFINITION The chemical reactions and physical changes involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2002-11-27 GO:0015803 branched-chain amino acid transport Added DEFINITION The directed movement of branched-chain aliphatic amino acids, amino acids with branched carbon skeleton without rings, into, out of, or within a cell.
2002-11-27 GO:0015658 branched-chain amino acid transmembrane transporter activity Added DEFINITION Enables the directed movement of branched-chain aliphatic amino acids, amino acids with branched carbon skeleton without rings, into, out of, or within a cell.
2002-11-27 GO:0004084 branched-chain-amino-acid transaminase activity Added DEFINITION Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
2002-11-27 GO:0016132 brassinosteroid biosynthetic process Added DEFINITION The formation from simpler components of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
2002-11-27 GO:0016133 brassinosteroid catabolic process Added DEFINITION The breakdown into simpler components of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
2002-11-27 GO:0009742 brassinosteroid mediated signaling pathway Added DEFINITION Signal transduction pathway mediated by the perception of brassinosteroid.
2002-11-27 GO:0016131 brassinosteroid metabolic process Added DEFINITION The chemical reactions and physical changes involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
2002-11-27 GO:0019806 bromide peroxidase activity Added DEFINITION Catalysis of the reaction: 2 RH + 2 bromide + hydrogen peroxide = 2 RBr + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.
2002-11-27 GO:0018881 bromoxynil metabolic process Added DEFINITION The chemical reactions and physical changes involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants.
2002-11-27 GO:0018761 bromoxynil nitrilase activity Added DEFINITION Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxy-benzoate + NH3. Involved in the bacterial degradation of the herbicide bromoxynil.
2002-11-27 GO:0005933 cellular bud Added DEFINITION A daughter cell of an organism that reproduces by budding; formed by pinching off part of the parent cell.
2002-11-27 GO:0005935 cellular bud neck Added DEFINITION The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
2002-11-27 GO:0007115 bud site selection/establishment of cell polarity (sensu Saccharomyces) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0005934 cellular bud tip Added DEFINITION The end of a bud distal to the site of attachment to the mother cell.
2002-11-27 GO:0007114 cell budding Added DEFINITION A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
2002-11-27 GO:0019650 glucose catabolic process to butanediol Added DEFINITION An anaerobic process in which glucose is fermented, with the production of 2,3-butanediol and other substances; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.
2002-11-27 GO:0046358 butyrate biosynthetic process Added DEFINITION The formation from simpler components of butyrate, the anion of butyric acid.
2002-11-27 GO:0046359 butyrate catabolic process Added DEFINITION The breakdown into simpler components of butyrate, the anion of butyric acid.
2002-11-27 GO:0030645 glucose catabolic process to butyrate Added DEFINITION An anaerobic process in which glucose is fermented, with the production of acetic acid, butyric acid, carbon dioxide, and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.
2002-11-27 GO:0019605 butyrate metabolic process Added DEFINITION The chemical reactions and physical changes involving butyrate, the anion of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.
2002-11-27 GO:0018734 butyrolactone hydrolase activity Added DEFINITION Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.
2002-11-27 GO:0004085 butyryl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: butanoyl-CoA + ETF = 2-butenoyl-CoA + reduced ETF.
2002-11-27 GO:0015727 lactate transport Added DEFINITION Directed movement of lactate into, outside, or within a cell.
2002-11-27 GO:0007595 lactation Added DEFINITION The secretion of milk by the mammary gland.
2002-11-27 GO:0046573 lactonohydrolase activity Added DEFINITION Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.
2002-11-27 GO:0016686 lactoperoxidase activity Added DEFINITION Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
2002-11-27 GO:0030395 lactose binding Added DEFINITION Interacting selectively and stoichiometrically with lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.
2002-11-27 GO:0005989 lactose biosynthetic process Added DEFINITION The formation from simpler components of lactose, the disaccharide galactopyranosyl-glucose.
2002-11-27 GO:0005990 lactose catabolic process Added DEFINITION The breakdown into simpler components of lactose, the disaccharide galactopyranosyl-glucose.
2002-11-27 GO:0019512 lactose catabolic process via tagatose-6-phosphate Added DEFINITION The breakdown into simpler components of lactose, via the intermediate tagatose-6-phosphate.
2002-11-27 GO:0019515 lactose catabolic process via UDP-galactose Added DEFINITION The breakdown into simpler components of lactose, via the intermediate UDP-galactose.
2002-11-27 GO:0019513 lactose catabolic process, using glucoside 3-dehydrogenase Added DEFINITION The breakdown of lactose into simpler components, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13).
2002-11-27 GO:0005988 lactose metabolic process Added DEFINITION The chemical reactions and physical changes involving lactose, the disaccharide galactopyranosyl-glucose.
2002-11-27 GO:0004461 lactose synthase activity Added DEFINITION Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.
2002-11-27 GO:0030027 lamellipodium Updated DEFINITION A thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.
2002-11-27 GO:0001572 lactosylceramide biosynthetic process Added DEFINITION The formation from simpler components of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
2002-11-27 GO:0046478 lactosylceramide metabolic process Added DEFINITION The chemical reactions and physical changes involving lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
2002-11-27 GO:0018819 lactoyl-CoA dehydratase activity Added DEFINITION Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.
2002-11-27 GO:0004462 lactoylglutathione lyase activity Added DEFINITION Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
2002-11-27 GO:0030032 lamellipodium assembly Updated DEFINITION Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
2002-11-27 GO:0005521 lamin binding Added DEFINITION Interacting selectively and stoichiometrically with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
2002-11-27 GO:0005606 laminin-1 complex Updated DEFINITION Laminins are glycoproteins that are major constituents of the basement membrane of cells. Laminins are trimeric molecules; laminin-1 is an alpha1 beta1 gamma1 trimer.
2002-11-27 GO:0005607 laminin-2 complex Updated DEFINITION Laminins are glycoproteins that are major constituents of the basement membrane of cells. Laminins are trimeric molecules; laminin-2 is an alpha2, beta1 gamma1 trimer.
2002-11-27 GO:0005608 laminin-3 complex Updated DEFINITION Laminins are glycoproteins that are major constituents of the basement membrane of cells. Laminins are trimeric molecules; laminin-3 is an alpha1 beta2 gamma1 trimer.
2002-11-27 GO:0018264 isopeptide cross-linking via N-(L-isoaspartyl)-glycine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to form a N-(L-isoaspartyl)-glycine cross-link.
2002-11-27 GO:0018263 isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine forming N-(L-isoaspartyl)-L-cysteine.
2002-11-27 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine forming N6-(L-isoglutamyl)-L-lysine.
2002-11-27 GO:0018276 isopeptide cross-linking via N6-glycyl-L-lysine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to form a N6-glycyl-L-lysine cross-link.
2002-11-27 GO:0018458 isopiperitenol dehydrogenase activity Added DEFINITION Catalysis of the reaction: (-)-trans-isopiperitenol + NAD+ = (-)-isopiperitenone + NADH + H+.
2002-11-27 GO:0008299 isoprenoid biosynthetic process Added DEFINITION The formation from simpler components of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2002-11-27 GO:0045162 clustering of voltage-gated sodium channels Added DEFINITION The process by which voltage gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.
2002-11-27 GO:0019597 (R)-mandelate catabolic process to benzoate Added DEFINITION The breakdown of (R)-mandelate into simpler components, including benzoate.
2002-11-27 GO:0019598 (R)-mandelate catabolic process to catechol Added DEFINITION The breakdown of (R)-mandelate into simpler components, including catechol.
2002-11-27 GO:0000721 (R,R)-butanediol dehydrogenase activity Added DEFINITION Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+.
2002-11-27 GO:0003973 (S)-2-hydroxy-acid oxidase activity Added DEFINITION Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.
2002-11-27 GO:0042188 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process Added DEFINITION The breakdown into simpler components of 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2002-11-27 GO:0018977 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2002-11-27 GO:0018976 1,2,3-tribromopropane metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.
2002-11-27 GO:0018911 1,2,4-trichlorobenzene metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.
2002-11-27 GO:0046509 1,2-diacylglycerol 3-beta-galactosyltransferase activity Added DEFINITION Catalysis of the reaction: UDPgalactose + 1,2-diacylglycerol = UDP + 3-beta-D-galactosyl-1,2-diacylglycerol.
2002-11-27 GO:0019260 1,2-dichloroethane catabolic process Added DEFINITION The breakdown into simpler components of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
2002-11-27 GO:0018899 1,2-dichloroethane metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
2002-11-27 GO:0018505 cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity Added DEFINITION Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.
2002-11-27 GO:0018521 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ = 3-methylcatechol + NADH + H+ + carbon dioxide.
2002-11-27 GO:0018718 1,2-dihydroxy-phenanthrene glycosyltransferase activity Added DEFINITION Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDPglucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.
2002-11-27 GO:0003843 1,3-beta-D-glucan synthase activity Added DEFINITION Catalysis of the reaction: UDP-glucose + (1,3)-beta-D-glucosyl(N) = UDP + (1,3)-beta-D-glucosyl(N+1).
2002-11-27 GO:0019564 aerobic glycerol catabolic process Added DEFINITION The breakdown into simpler components of glycerol, 1,2,3-propanetriol, in the presence of oxygen.
2002-11-27 GO:0018935 aerobic nitrilotriacetate metabolic process Added DEFINITION The chemical reactions and physical changes involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen.
2002-11-27 GO:0018946 aerobic organosilicon metabolic process Added DEFINITION The chemical reactions and physical changes involving organosilicones, organic compounds that contain silicone, in the presence of oxygen.
2002-11-27 GO:0046190 aerobic phenol-containing compound biosynthetic process Added DEFINITION The formation from simpler components of phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
2002-11-27 GO:0046191 aerobic phenol-containing compound catabolic process Added DEFINITION The breakdown into simpler components of phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
2002-11-27 GO:0018959 aerobic phenol-containing compound metabolic process Added DEFINITION The chemical reactions and physical changes involving phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
2002-11-27 GO:0009454 aerotaxis Added DEFINITION The movement of a motile cell in response to atmospheric oxygen.
2002-11-27 GO:0045122 aflatoxin biosynthetic process Added DEFINITION The formation from simpler components of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
2002-11-27 GO:0046223 aflatoxin catabolic process Added DEFINITION The breakdown into simpler components of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
2002-11-27 GO:0046222 aflatoxin metabolic process Added DEFINITION The chemical reactions and physical changes involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
2002-11-27 GO:0007334 agglutination (sensu Saccharomyces) Added DEFINITION Aggregation or adhesion of the haploid mating type cells (a and alpha cells) prior to mating via complementary cell surface glycoproteins, a-agglutinin and alpha-agglutinin.
2002-11-27 GO:0007568 aging Added DEFINITION The inherent decline over time, from the optimal fertility and viability of early maturity, that culminates in death and may be preceded by other indications, such as sterility.
2002-11-27 GO:0007578 aging dependent sterility (sensu Saccharomyces) Added DEFINITION A haploid's inability to mate due to the loss of silencing at the mating type loci, resulting in expression of both of the normally silent mating type cassettes.
2002-11-27 GO:0008783 agmatinase activity Added DEFINITION Catalysis of the reaction: agmatine + H2O = putrescine + urea.
2002-11-27 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2002-11-27 GO:0006523 alanine biosynthetic process Added DEFINITION The formation from simpler components of alanine, 2-aminopropanoic acid.
2002-11-27 GO:0019272 L-alanine biosynthetic process from pyruvate Added DEFINITION The formation of alanine from simpler components, including pyruvate.
2002-11-27 GO:0019273 L-alanine biosynthetic process via ornithine Added DEFINITION The formation from simpler components of alanine, via the intermediate ornithine.
2002-11-27 GO:0006524 alanine catabolic process Added DEFINITION The breakdown into simpler components of alanine, 2-aminopropanoic acid.
2002-11-27 GO:0019481 L-alanine catabolic process, by transamination Added DEFINITION The breakdown into simpler components of alanine by transamination.
2002-11-27 GO:0004166 dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.
2002-11-27 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity Added DEFINITION Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
2002-11-27 GO:0004581 dolichyl-phosphate beta-glucosyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.
2002-11-27 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide.
2002-11-27 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity Added DEFINITION Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.
2002-11-27 GO:0046566 DOPA dioxygenase activity Added DEFINITION Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid.
2002-11-27 GO:0004167 dopachrome isomerase activity Added DEFINITION Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.
2002-11-27 GO:0042416 dopamine biosynthetic process Added DEFINITION The formation from simpler components of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0006585 dopamine biosynthetic process from tyrosine Added DEFINITION The formation of dopamine, a catecholamine neurotransmitter, from tyrosine (3,4-dihydroxy-L-phenylalanine) via the aromatic-L-amino-acid decarboxylase (EC:4.1.1.28).
2002-11-27 GO:0042420 dopamine catabolic process Added DEFINITION The breakdown into simpler components of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0001590 dopamine D1 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D1 receptors.
2002-11-27 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs Added DEFINITION A G-protein coupled receptor that binds the neurotransmitter dopamine and activates adenylate cyclase via coupling to Gs.
2002-11-27 GO:0001670 dopamine D2 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D4 receptors.
2002-11-27 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go Added DEFINITION A G-protein coupled receptor that binds the neurotransmitter dopamine and inhibits adenylate cyclase via coupling to Gi/Go.
2002-11-27 GO:0001592 dopamine D3 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D3 receptors.
2002-11-27 GO:0001593 dopamine D4 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D4 receptors.
2002-11-27 GO:0001589 dopamine D5 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D5 receptors.
2002-11-27 GO:0042417 dopamine metabolic process Added DEFINITION The chemical reactions and physical changes involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0004952 dopamine neurotransmitter receptor activity Added DEFINITION A G-protein coupled receptor that uses the neurotransmitter dopamine as a ligand.
2002-11-27 GO:0015872 dopamine transport Added DEFINITION The directed movement of dopamine into, out of, or within a cell. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0009397 folic acid-containing compound catabolic process Added DEFINITION The breakdown into simpler components of folic acid and its derivatives.
2002-11-27 GO:0006760 folic acid-containing compound metabolic process Added DEFINITION The chemical reactions and physical changes involving folic acid and its derivatives.
2002-11-27 GO:0005542 folic acid binding Added DEFINITION Interacting selectively and stoichiometrically with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
2002-11-27 GO:0046656 folic acid biosynthetic process Added DEFINITION The formation from simpler components of folic acid, pteroylglutamic acid.
2002-11-27 GO:0046657 folic acid catabolic process Added DEFINITION The breakdown into simpler components of folic acid, pteroylglutamic acid.
2002-11-27 GO:0046655 folic acid metabolic process Added DEFINITION The chemical reactions and physical changes involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
2002-11-27 GO:0016913 follicle-stimulating hormone activity Added DEFINITION A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland.
2002-11-27 GO:0004326 tetrahydrofolylpolyglutamate synthase activity Added DEFINITION Catalysis of the reaction: ATP + tetrahydrofolyl-[Glu](n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-[Glu](n+1).
2002-11-27 GO:0020020 food vacuole Added DEFINITION Vacuole within a parasite used for digestion of the host cell cytoplasm.
2002-11-27 GO:0005506 iron ion binding Added DEFINITION Interacting selectively and stoichiometrically with iron (Fe).
2002-11-27 GO:0006879 cellular iron ion homeostasis Added DEFINITION The regulation of the levels, transport, and metabolism of iron ions within a cell or between a cell and its external environment.
2002-11-27 GO:0016948 iron hydrogenase activity Updated DEFINITION Iron-sulfur-containing hydrogenase ([Fe] hydrogenase) with two ferredoxin-type (4Fe-4S) clusters and an atypical iron-sulfur center believed to be involved in the activation of H2. The [Fe] hydrogenase has the highest specific activity in the evolution and consumption of hydrogen and in the proton-deuterium exchange reaction and this enzyme is the most sensitive to CO and NO2-.
2002-11-27 GO:0018306 iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide Added DEFINITION The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.
2002-11-27 GO:0018300 iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide Added DEFINITION OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide.
2002-11-27 GO:0018441 iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide Added DEFINITION The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.
2002-11-27 GO:0019709 iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide Added DEFINITION The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.
2002-11-27 GO:0018285 iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide Added DEFINITION The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.
2002-11-27 GO:0018288 iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide Added DEFINITION The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.
2002-11-27 GO:0019477 L-lysine catabolic process Added DEFINITION The breakdown into simpler components of L-lysine, the levorotatory isomer of (S)-2,6-diaminohexanoic acid.
2002-11-27 GO:0019475 L-lysine catabolic process to acetate Added DEFINITION The breakdown of L-lysine into simpler components, including acetate.
2002-11-27 GO:0019474 L-lysine catabolic process to acetyl-CoA Added DEFINITION The breakdown of L-lysine into simpler components, including acetyl-CoA.
2002-11-27 GO:0019473 L-lysine catabolic process to glutarate, by acetylation Added DEFINITION The breakdown of L-lysine into simpler components, including glutarate, by acetylation.
2002-11-27 GO:0015661 L-lysine efflux transmembrane transporter activity Added DEFINITION Catalysis of the stereospecific transfer of L-lysine, 2,6-diaminohexanoic acid, across a biological membrane out of a cell.
2002-11-27 GO:0046440 L-lysine metabolic process Added DEFINITION The chemical reactions and physical changes involving L-lysine, the levorotatory isomer of (S)-2,6-diaminohexanoic acid.
2002-11-27 GO:0019324 L-lyxose metabolic process Added DEFINITION The chemical reactions and physical changes involving L-lyxose, the levorotatory isomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.
2002-11-27 GO:0030060 L-malate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+. Also oxidizes some other 2-hydroxydicarboxylic acids.
2002-11-27 GO:0019680 L-methylmalonyl-CoA biosynthetic process Added DEFINITION The formation from simpler components of L-methylmalonyl-CoA, the levorotatory isomer of 2-carboxypropanoyl-CoA.
2002-11-27 GO:0046491 L-methylmalonyl-CoA metabolic process Added DEFINITION The chemical reactions and physical changes involving L-methylmalonyl-CoA, the levorotatory isomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.
2002-11-27 GO:0008740 L-rhamnose isomerase activity Added DEFINITION Catalysis of the reaction: L-rhamnose = L-rhamnulose.
2002-11-27 GO:0008741 ribulokinase activity Added DEFINITION Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.
2002-11-27 GO:0008742 L-ribulose-phosphate 4-epimerase activity Added DEFINITION Catalysis of the reaction: L-ribulose 5-phosphate = D-xylose 5-phosphate.
2002-11-27 GO:0003941 L-serine ammonia-lyase activity Added DEFINITION Catalysis of the reaction: L-serine = pyruvate + ammonia.
2002-11-27 GO:0019312 L-sorbose metabolic process Added DEFINITION The chemical reactions and physical changes involving sorbose, the levorotatory isomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.
2002-11-27 GO:0008743 L-threonine 3-dehydrogenase activity Added DEFINITION Catalysis of the reaction: L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH + H+.
2002-11-27 GO:0008744 L-xylulokinase activity Added DEFINITION Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate.
2002-11-27 GO:0008471 laccase activity Added DEFINITION Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.
2002-11-27 GO:0008911 lactaldehyde dehydrogenase activity Added DEFINITION Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.
2002-11-27 GO:0008912 lactaldehyde reductase activity Added DEFINITION Catalysis of the reaction: (R) [or (S)]-propane-1,2-diol + NAD+ = (R) [or (S)]-lactaldehyde + NADH + H+.
2002-11-27 GO:0000016 lactase activity Added DEFINITION Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.
2002-11-27 GO:0019249 lactate biosynthetic process Added DEFINITION The formation from simpler components of lactate, the anion of lactic acid.
2002-11-27 GO:0019244 lactate biosynthetic process from pyruvate Added DEFINITION The formation of lactate from simpler components, including pyruvate.
2002-11-27 GO:0004457 lactate dehydrogenase activity Added DEFINITION Catalysis of the oxidation of lactate to produce pyruvate.
2002-11-27 GO:0006089 lactate metabolic process Updated DEFINITION The chemical reactions and physical changes involving lactate, the anion of lactic acid.
2002-11-27 GO:0019247 lactate racemization Added DEFINITION Partial conversion of one lactate enantiomorph into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.
2002-11-27 GO:0004091 carboxylesterase activity Added DEFINITION Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion.
2002-11-27 GO:0046394 carboxylic acid biosynthetic process Added DEFINITION The formation from simpler components of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
2002-11-27 GO:0046395 carboxylic acid catabolic process Added DEFINITION The breakdown into simpler components of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
2002-11-27 GO:0019752 carboxylic acid metabolic process Added DEFINITION The chemical reactions and physical changes involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
2002-11-27 GO:0008806 carboxymethylenebutenolidase activity Added DEFINITION Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.
2002-11-27 GO:0004182 carboxypeptidase A activity Added DEFINITION Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid.
2002-11-27 GO:0004186 carboxypeptidase C activity Added DEFINITION Catalysis of the release of a C-terminal amino acid with a broad specificity.
2002-11-27 GO:0004187 carboxypeptidase D activity Added DEFINITION Catalysis of the preferential release of a C-terminal arginine or lysine residue.
2002-11-27 GO:0004183 carboxypeptidase E activity Added DEFINITION Catalysis of the reaction: peptidyl-L-lysine(or L-arginine) + H2O = peptide + L-lysine(or L-arginine).
2002-11-27 GO:0008807 carboxyvinyl-carboxyphosphonate phosphorylmutase activity Added DEFINITION Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + carbon dioxide.
2002-11-27 GO:0008808 cardiolipin synthase activity Added DEFINITION Catalysis of the condensation of two 3-phosphatidylglycerol molecules, by transferring the phosphatidyl group from one to the other, producing glycerol and diphosphatidyl glycerol.
2002-11-27 GO:0045329 carnitine biosynthetic process Added DEFINITION The formation from simpler components of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
2002-11-27 GO:0042413 carnitine catabolic process Added DEFINITION The breakdown into simpler components of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
2002-11-27 GO:0009437 carnitine metabolic process Added DEFINITION The chemical reactions and physical changes involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
2002-11-27 GO:0019254 carnitine metabolic process, CoA-linked Added DEFINITION The chemical reactions and physical changes involving carnitine, where metabolism is linked to CoA.
2002-11-27 GO:0004092 carnitine O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine.
2002-11-27 GO:0004093 carnitine O-acetyltransferase I activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine.
2002-11-27 GO:0004094 carnitine O-acetyltransferase II activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine.
2002-11-27 GO:0008458 carnitine O-octanoyltransferase activity Added DEFINITION Catalysis of the reaction: octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine.
2002-11-27 GO:0004095 carnitine O-palmitoyltransferase activity Added DEFINITION Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
2002-11-27 GO:0006853 carnitine shuttle Added DEFINITION The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane (GO:0005743) with unacylated carnitine.
2002-11-27 GO:0016719 carotene 7,8-desaturase activity Added DEFINITION Catalysis of the reaction: neurosporene + AH2 + O2 = lycopene + A + 2 H2O.
2002-11-27 GO:0000254 C-4 methylsterol oxidase activity Updated DEFINITION Catalysis of the oxidation of the 4-alpha methyl group of 4,4-dimethylzymosterol, the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol in ergosterol biosynthesis.
2002-11-27 GO:0000248 C-5 sterol desaturase activity Updated DEFINITION Catalysis of the introduction of a C-5 double bond in the B ring of ergosterol.
2002-11-27 GO:0000247 C-8 sterol isomerase activity Updated DEFINITION Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.
2002-11-27 GO:0016493 C-C chemokine receptor activity Added DEFINITION A chemokine receptor that functions primarily in mononuclear cells. The ligands do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
2002-11-27 GO:0018103 protein C-linked glycosylation Added DEFINITION The glycosylation of a peptidyl-amino acid residue at a C atom.
2002-11-27 GO:0018406 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan Added DEFINITION The glycosylation of a peptidyl-tryptophan residue by the attachment of alpha-mannopyranose to the indole ring.
2002-11-27 GO:0018034 C-terminal peptidyl-alanine amidation Added DEFINITION The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.
2002-11-27 GO:0009224 CMP biosynthetic process Added DEFINITION The formation from simpler components of CMP, cytidine monophosphate.
2002-11-27 GO:0006248 CMP catabolic process Added DEFINITION The breakdown into simpler components of CMP, cytidine monophosphate.
2002-11-27 GO:0046035 CMP metabolic process Added DEFINITION The chemical reactions and physical changes involving CMP, cytidine monophosphate.
2002-11-27 GO:0006055 CMP-N-acetylneuraminate biosynthetic process Added DEFINITION The formation from simpler components of CMP-N-acetylneuraminate, a compound of cytidine monophosphate and the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
2002-11-27 GO:0046381 CMP-N-acetylneuraminate metabolic process Added DEFINITION The chemical reactions and physical changes involving CMP-N-acetylneuraminate, a compound of cytidine monophosphate and the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
2002-11-27 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity Added DEFINITION Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.
2002-11-27 GO:0015782 CMP-N-acetylneuraminate transport Added DEFINITION The directed movement of CMP-sialic acid, a compound composed of sialic acid and cytidine monophosphate, into, out of, or within a cell.
2002-11-27 GO:0042151 nematocyst Added DEFINITION An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.
2002-11-27 GO:0006613 cotranslational protein targeting to membrane Added DEFINITION The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the ER lumen occurs in this manner.
2002-11-27 GO:0005905 coated pit Added DEFINITION An invagination of the cell membrane of many eukaryotic cells, concerned in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane. During endocytosis it is converted into a coated vesicle. The coat is of clathrin.
2002-11-27 GO:0030135 coated vesicle Added DEFINITION Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
2002-11-27 GO:0005799 coatomer Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity Added DEFINITION Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin.
2002-11-27 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity Added DEFINITION Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
2002-11-27 GO:0003887 DNA-directed DNA polymerase activity Updated DEFINITION Enzymes that catalyze the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2002-11-27 GO:0003899 DNA-directed RNA polymerase activity Added DEFINITION Catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2002-11-27 GO:0003900 DNA-directed RNA polymerase I activity Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
2002-11-27 GO:0003901 DNA-directed RNA polymerase II activity Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
2002-11-27 GO:0003902 DNA-directed RNA polymerase III activity Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
2002-11-27 GO:0018142 protein-DNA covalent cross-linking Added DEFINITION The formation of a covalent cross-link between DNA and a protein.
2002-11-27 GO:0018145 protein-DNA covalent cross-linking via peptidyl-serine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine.
2002-11-27 GO:0018164 protein-DNA covalent cross-linking via peptidyl-threonine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.
2002-11-27 GO:0045327 protein-DNA covalent cross-linking via peptidyl-tyrosine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue.
2002-11-27 GO:0045326 protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.
2002-11-27 GO:0018163 protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.
2002-11-27 GO:0004165 dodecenoyl-CoA delta-isomerase activity Added DEFINITION Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA.
2002-11-27 GO:0018909 dodecyl sulfate metabolic process Added DEFINITION The chemical reactions and physical changes involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.
2002-11-27 GO:0019408 dolichol biosynthetic process Added DEFINITION The formation from simpler components of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
2002-11-27 GO:0004168 dolichol kinase activity Added DEFINITION Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.
2002-11-27 GO:0019348 dolichol metabolic process Added DEFINITION The chemical reactions and physical changes involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
2002-11-27 GO:0006489 dolichyl diphosphate biosynthetic process Added DEFINITION The formation from simpler components of dolichyl diphosphate, a diphosphorylated dolichol derivative.
2002-11-27 GO:0046465 dolichyl diphosphate metabolic process Added DEFINITION The chemical reactions and physical changes involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.
2002-11-27 GO:0042283 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Added DEFINITION The addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
2002-11-27 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Added DEFINITION The addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
2002-11-27 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity Added DEFINITION Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
2002-11-27 GO:0006876 cellular cadmium ion homeostasis Added DEFINITION The regulation of the levels, transport, and metabolism of cadmium ions within a cell or between a cell and its external environment.
2002-11-27 GO:0019830 cadmium sensitivity/resistance Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0015434 cadmium-transporting ATPase activity Updated DEFINITION An ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that exports some heavy metals, especially cadmium, from the cytosol into the vacuole; does not undergo phosphorylation during the transport process.
2002-11-27 GO:0042409 caffeoyl-CoA O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.
2002-11-27 GO:0015030 Cajal body Updated DEFINITION A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Gall argues that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
2002-11-27 GO:0004813 alanine-tRNA ligase activity Added DEFINITION Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
2002-11-27 GO:0046165 alcohol biosynthetic process Added DEFINITION The formation from simpler components of alcohols, any of a class of alkyl compounds containing a hydroxyl group.
2002-11-27 GO:0046164 alcohol catabolic process Added DEFINITION The breakdown into simpler components of alcohols, any of a class of alkyl compounds containing a hydroxyl group.
2002-11-27 GO:0004022 alcohol dehydrogenase (NAD) activity Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0018468 alcohol dehydrogenase (acceptor) activity Added DEFINITION Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor.
2002-11-27 GO:0008106 alcohol dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
2002-11-27 GO:0004025 alcohol dehydrogenase activity, iron-dependent Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0004023 alcohol dehydrogenase activity, metal ion-independent Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0004024 alcohol dehydrogenase activity, zinc-dependent Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0006066 alcohol metabolic process Added DEFINITION The chemical reactions and physical changes involving alcohols, any of a class of alkyl compounds containing a hydroxyl group.
2002-11-27 GO:0004026 alcohol O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester.
2002-11-27 GO:0004027 alcohol sulfotransferase activity Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylylsulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
2002-11-27 GO:0019578 aldaric acid biosynthetic process Added DEFINITION The formation from simpler components of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
2002-11-27 GO:0019579 aldaric acid catabolic process Added DEFINITION The breakdown into simpler components of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
2002-11-27 GO:0019577 aldaric acid metabolic process Added DEFINITION The chemical reactions and physical changes involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
2002-11-27 GO:0046184 aldehyde biosynthetic process Added DEFINITION The formation from simpler components of aldehydes, any organic compound with the formula R-CH=O.
2002-11-27 GO:0046185 aldehyde catabolic process Added DEFINITION The breakdown into simpler components of aldehydes, any organic compound with the formula R-CH=O.
2002-11-27 GO:0009924 octadecanal decarbonylase activity Added DEFINITION Catalysis of the reaction: octadecanal = heptadecane + CO.
2002-11-27 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2e- + 3-chloroacrylic acid.
2002-11-27 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity Added DEFINITION Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.
2002-11-27 GO:0008300 isoprenoid catabolic process Added DEFINITION The breakdown into simpler components of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2002-11-27 GO:0006720 isoprenoid metabolic process Updated DEFINITION The chemical reactions and physical changes involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2002-11-27 GO:0007119 budding cell isotropic bud growth Added DEFINITION Unlocalized bud growth such that the entire surface of the bud expands evenly.
2002-11-27 GO:0045190 isotype switching Added DEFINITION The switching between different isotypes of a molecule. For example, the switch of immunoglobulin isotype that occurs as the immune response progresses is IgM to IgG. This involves only the constant region of the heavy chains, the light chain and variable regions of the heavy chain remaining the same and involves the switch regions, upstream (on the 5' side) of the constant region genes, at which recombination occurs. Similarly, IgM and IgD with the same variable region of the heavy chain, but with different heavy chain constant regions, seem to coexist on the surface of some lymphocytes.
2002-11-27 GO:0046293 formaldehyde biosynthetic process Added DEFINITION The formation from simpler components of formaldehyde (methanal, H2C=O), the simplest aldehyde.
2002-11-27 GO:0046294 formaldehyde catabolic process Added DEFINITION The breakdown into simpler components of formaldehyde (methanal, H2C=O), the simplest aldehyde.
2002-11-27 GO:0004327 formaldehyde dehydrogenase (glutathione) activity Added DEFINITION Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+.
2002-11-27 GO:0046292 formaldehyde metabolic process Added DEFINITION The chemical reactions and physical changes involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
2002-11-27 GO:0004328 formamidase activity Added DEFINITION Catalysis of the reaction: formamide + H2O = formate + ammonia.
2002-11-27 GO:0008862 formate acetyltransferase activating enzyme activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate acetyltransferase]-glycine = 5'-deoxyadenosine + methionine + flavodoxin + [formate acetyltransferase]-glycine-2-yl radical.
2002-11-27 GO:0015943 formate biosynthetic process Added DEFINITION The formation from simpler components of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
2002-11-27 GO:0008861 formate C-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.
2002-11-27 GO:0042183 formate catabolic process Added DEFINITION The breakdown into simpler components of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
2002-11-27 GO:0008863 formate dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: formate + NAD+ = carbon dioxide + NADH + H+.
2002-11-27 GO:0009326 formate dehydrogenase complex Added DEFINITION An enzyme that catalyzes the dehydrogenation of formate to produce carbon dioxide.
2002-11-27 GO:0015942 formate metabolic process Added DEFINITION The chemical reactions and physical changes involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
2002-11-27 GO:0015724 formate transport Added DEFINITION Directed movement of formate into, outside, or within a cell.
2002-11-27 GO:0004329 formate-tetrahydrofolate ligase activity Added DEFINITION Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
2002-11-27 GO:0001704 formation of primary germ layer Added DEFINITION The formation of the ectoderm, mesoderm and endoderm during gastrulation.
2002-11-27 GO:0001732 formation of translation initiation complex Added DEFINITION Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methiionyl/formyl-methionyl-tRNA positioned at the P site.
2002-11-27 GO:0001677 formation of translation initiation ternary complex Added DEFINITION Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
2002-11-27 GO:0001731 formation of translation preinitiation complex Added DEFINITION The joining of the small ribosomal subunit, ternary complex, and mRNA.
2002-11-27 GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity Added DEFINITION Catalysis of the reaction: 5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH3.
2002-11-27 GO:0030407 formimidoyltransferase activity Added DEFINITION Catalysis of the transfer of a formimino group from 5-formimidoyltetrahydrofolate to an acceptor molecule such as an amino acid.
2002-11-27 GO:0018493 formylmethanofuran dehydrogenase activity Added DEFINITION Catalysis of the reaction: formylmethanofuran + H2O + acceptor = carbon dioxide + methanofuran + reduced acceptor.
2002-11-27 GO:0018884 carbazole metabolic process Added DEFINITION The chemical reactions and physical changes involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
2002-11-27 GO:0030246 carbohydrate binding Added DEFINITION Interacting selectively and stoichiometrically with any carbohydrate.
2002-11-27 GO:0016051 carbohydrate biosynthetic process Added DEFINITION The formation from simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
2002-11-27 GO:0016052 carbohydrate catabolic process Added DEFINITION The breakdown into simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
2002-11-27 GO:0009756 carbohydrate mediated signaling Added DEFINITION Signal transduction pathway mediated by the perception of carbohydrate.
2002-11-27 GO:0005975 carbohydrate metabolic process Added DEFINITION The chemical reactions and physical changes involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
2002-11-27 GO:0009758 carbohydrate utilization Added DEFINITION Series of processes that involve carbohydrate sensing, carbohydrate transportation and carbohydrate metabolism which lead to the utilization of carbohydrates.
2002-11-27 GO:0030634 carbon fixation by acetyl-CoA pathway Added DEFINITION A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide.
2002-11-27 GO:0018492 carbon-monoxide dehydrogenase (acceptor) activity Added DEFINITION Catalysis of the reaction: CO + H2O + acceptor = carbon dioxide + reduced acceptor.
2002-11-27 GO:0008805 carbon-monoxide oxygenase activity Added DEFINITION Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.
2002-11-27 GO:0019382 carbon tetrachloride catabolic process Added DEFINITION The breakdown into simpler components of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
2002-11-27 GO:0018885 carbon tetrachloride metabolic process Added DEFINITION The chemical reactions and physical changes involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
2002-11-27 GO:0004089 carbonate dehydratase activity Added DEFINITION Catalysis of the reaction: H2CO3 = carbon dioxide + H2O.
2002-11-27 GO:0004090 carbonyl reductase (NADPH) activity Added DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
2002-11-27 GO:0009702 L-arabinokinase activity Added DEFINITION Catalysis of the reaction: ATP + L-arabinose = ADP + beta-L-arabinose 1-phosphate.
2002-11-27 GO:0019572 L-arabinose catabolic process Added DEFINITION The breakdown into simpler components of L-arabinose, the levorotatory isomer of arabino-pentose.
2002-11-27 GO:0019570 L-arabinose catabolic process to 2-oxoglutarate Added DEFINITION The breakdown of L-arabinose into simpler components, including 2-oxoglutarate.
2002-11-27 GO:0019569 L-arabinose catabolic process to xylulose 5-phosphate Added DEFINITION The breakdown of L-arabinose into simpler components, including xylulose 5-phosphate.
2002-11-27 GO:0008733 L-arabinose isomerase activity Added DEFINITION Catalysis of the reaction: L-arabinose = L-ribulose.
2002-11-27 GO:0046373 L-arabinose metabolic process Added DEFINITION The chemical reactions and physical changes involving L-arabinose, the levorotatory isomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides and so on.
2002-11-27 GO:0008447 L-ascorbate oxidase activity Added DEFINITION Catalysis of the reaction: 2 L-ascorbate + O2 = 2 dehydroascorbate + 2 H2O.
2002-11-27 GO:0016688 L-ascorbate peroxidase activity Added DEFINITION Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.
2002-11-27 GO:0019853 L-ascorbic acid biosynthetic process Added DEFINITION The formation from simpler components of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
2002-11-27 GO:0019854 L-ascorbic acid catabolic process Added DEFINITION The breakdown into simpler components of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
2002-11-27 GO:0019852 L-ascorbic acid metabolic process Added DEFINITION The chemical reactions and physical changes involving L-ascorbic acid, a carbohydrate-like vitamin containing six carbon atoms per molecule. Widely distributed in fruit and vegetables.
2002-11-27 GO:0008734 L-aspartate oxidase activity Added DEFINITION Catalysis of the reaction: L-aspartate + H2O + O2 = oxaloacetate + ammonia + hydrogen peroxide.
2002-11-27 GO:0008735 carnitine dehydratase activity Added DEFINITION Catalysis of the reaction: L-carnitine = 4-(trimethylammonio)but-2-enoate + H2O.
2002-11-27 GO:0019448 L-cysteine catabolic process Added DEFINITION The breakdown into simpler components of L-cysteine, the levorotatory isomer of 2-amino-3-mercaptopropanoic acid.
2002-11-27 GO:0019449 L-cysteine catabolic process to hypotaurine Added DEFINITION The breakdown of L-cysteine into simpler components, including hypotaurine.
2002-11-27 GO:0019450 L-cysteine catabolic process to pyruvate Added DEFINITION The breakdown of L-cysteine into simpler components, including pyruvate.
2002-11-27 GO:0019451 L-cysteine catabolic process to pyruvate, using cysteine dioxygenase Added DEFINITION The breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).
2002-11-27 GO:0019452 L-cysteine catabolic process to taurine Added DEFINITION The breakdown of L-cysteine into simpler components, including taurine.
2002-11-27 GO:0019453 L-cysteine catabolic process via cystine Added DEFINITION The breakdown into simpler components of L-cysteine, via the intermediate cystine.
2002-11-27 GO:0019456 L-cysteine catabolic process via cystine, using cysteine transaminase Added DEFINITION The breakdown into simpler components, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3).
2002-11-27 GO:0019455 L-cysteine catabolic process via cystine, using cystine reductase Added DEFINITION The breakdown into simpler components, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6).
2002-11-27 GO:0019454 L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase Added DEFINITION The breakdown into simpler components, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4).
2002-11-27 GO:0046439 L-cysteine metabolic process Added DEFINITION The chemical reactions and physical changes involving L-cysteine, the levorotatory isomer of 2-amino-3-mercaptopropanoic acid.
2002-11-27 GO:0045438 delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity Added DEFINITION Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.
2002-11-27 GO:0006005 L-fucose biosynthetic process Added DEFINITION The formation from simpler components of L-fucose (6-deoxy-L-galactose).
2002-11-27 GO:0042355 L-fucose catabolic process Added DEFINITION The breakdown into simpler components of L-fucose (6-deoxy-Lgalactose).
2002-11-27 GO:0008736 L-fucose isomerase activity Added DEFINITION Catalysis of the reaction: L-fucose = L-fuculose.
2002-11-27 GO:0042354 L-fucose metabolic process Added DEFINITION The chemical reactions and physical changes involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus spp., and in the cell wall matrix of higher plants.
2002-11-27 GO:0008737 L-fuculokinase activity Added DEFINITION Catalysis of the reaction: ATP + L-fuculose = ADP + L-fuculose 1-phosphate.
2002-11-27 GO:0018035 C-terminal peptidyl-arginine amidation Added DEFINITION The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.
2002-11-27 GO:0018036 C-terminal peptidyl-asparagine amidation Added DEFINITION The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein.
2002-11-27 GO:0018037 C-terminal peptidyl-aspartic acid amidation Added DEFINITION The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.
2002-11-27 GO:0018038 C-terminal peptidyl-cysteine amidation Added DEFINITION The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.
2002-11-27 GO:0018040 C-terminal peptidyl-glutamic acid amidation Added DEFINITION The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.
2002-11-27 GO:0018039 C-terminal peptidyl-glutamine amidation Added DEFINITION The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.
2002-11-27 GO:0018041 C-terminal peptidyl-glycine amidation Added DEFINITION The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein.
2002-11-27 GO:0018042 C-terminal peptidyl-histidine amidation Added DEFINITION The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.
2002-11-27 GO:0018043 C-terminal peptidyl-isoleucine amidation Added DEFINITION The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.
2002-11-27 GO:0018044 C-terminal peptidyl-leucine amidation Added DEFINITION The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.
2002-11-27 GO:0018045 C-terminal peptidyl-lysine amidation Added DEFINITION The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.
2002-11-27 GO:0018046 C-terminal peptidyl-methionine amidation Added DEFINITION The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.
2002-11-27 GO:0018047 C-terminal peptidyl-phenylalanine amidation Added DEFINITION The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.
2002-11-27 GO:0018170 C-terminal peptidyl-polyglutamic acid amidation Added DEFINITION The formation of a C-terminal peptidyl-polyglutamic acid to form an N-L-glutamyl-poly-L-glutamic acid C-terminus.
2002-11-27 GO:0018048 C-terminal peptidyl-proline amidation Added DEFINITION The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.
2002-11-27 GO:0018049 C-terminal peptidyl-serine amidation Added DEFINITION The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.
2002-11-27 GO:0018050 C-terminal peptidyl-threonine amidation Added DEFINITION The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.
2002-11-27 GO:0018051 C-terminal peptidyl-tryptophan amidation Added DEFINITION The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.
2002-11-27 GO:0018052 C-terminal peptidyl-tyrosine amidation Added DEFINITION The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.
2002-11-27 GO:0018053 C-terminal peptidyl-valine amidation Added DEFINITION The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.
2002-11-27 GO:0019132 C-terminal processing peptidase activity Added DEFINITION The specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then catalyzes cleavage at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.
2002-11-27 GO:0006503 C-terminal protein farnesylation Added DEFINITION OBSOLETE. The covalent or non-covalent attachment of a farnesyl moiety to the carboxy terminus of a protein.
2002-11-27 GO:0006504 C-terminal protein geranylgeranylation Added DEFINITION OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl moiety to the carboxy terminus of a protein.
2002-11-27 GO:0006501 C-terminal protein lipidation Added DEFINITION The covalent or non-covalent attachment of a lipid moiety to the carboxy terminus of a protein.
2002-11-27 GO:0006502 C-terminal protein prenylation Added DEFINITION OBSOLETE. The covalent or non-covalent attachment of a prenyl moiety to the carboxy terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.

Terms

Timestamp GO ID GO Term Name Action Category Detail
2002-11-27 GO:0019005 SCF ubiquitin ligase complex Updated TERM SCF ubiquitin ligase complex
2002-11-27 GO:0017133 mitochondrial electron transfer flavoprotein complex Updated TERM electron transfer flavoprotein complex (sensu Eukarya)
2002-11-27 GO:0045247 cytosolic electron transfer flavoprotein complex Updated TERM electron transfer flavoprotein complex (sensu Bacteria)
2002-11-27 GO:0046716 muscle cell cellular homeostasis Added TERM muscle maintenance
2002-11-27 GO:0046717 acid secretion Added TERM acid secretion

Definition/synonyms

Timestamp GO ID GO Term Name Action Category Detail
2002-11-27 GO:0018879 biphenyl metabolic process Added DEFINITION The chemical reactions and physical changes involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
2002-11-27 GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity Added DEFINITION Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.
2002-11-27 GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-guanosyl)tetraphosphate + H2O = GTP + GMP. Also acts on bis(5'-xanthosyl)-tetraphosphate and, more slowly, on bis(5'-adenosyl)-tetraphosphate and bis(5'-uridyl)-tetraphosphate.
2002-11-27 GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Added DEFINITION Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl)tetraphosphate + H2O = 2 ADP.
2002-11-27 GO:0004082 bisphosphoglycerate mutase activity Added DEFINITION Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.
2002-11-27 GO:0004083 bisphosphoglycerate 2-phosphatase activity Added DEFINITION Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 3-phosphoglycerate + phosphate.
2002-11-27 GO:0018750 biuret amidohydrolase activity Added DEFINITION Catalysis of the reaction: biuret + H2O = urea + carbon dioxide + ammonia.
2002-11-27 GO:0007350 blastoderm segmentation Added DEFINITION The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.
2002-11-27 GO:0008423 bleomycin hydrolase activity Added DEFINITION Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
2002-11-27 GO:0007596 blood coagulation Added DEFINITION The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
2002-11-27 GO:0003803 coagulation factor IXa activity Added DEFINITION Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa.
2002-11-27 GO:0003802 coagulation factor VIIa activity Added DEFINITION Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa.
2002-11-27 GO:0003804 coagulation factor Xa activity Added DEFINITION Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin.
2002-11-27 GO:0003805 coagulation factor XIa activity Added DEFINITION Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa.
2002-11-27 GO:0003806 coagulation factor XIIa activity Added DEFINITION Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.
2002-11-27 GO:0007598 blood coagulation, extrinsic pathway Added DEFINITION A pathway of blood coagulation in which the earlier stages of the cascade are bypassed and the activation of factor X to factor Xa is effected by the combination of factor VIIa + thromboplastin; this second pathway occurs when tissue extracts are present in optimal amounts and is much more rapid than the intrinsic pathway (Compare blood coagulation, intrinsic pathway GO:0007597).
2002-11-27 GO:0007597 blood coagulation, intrinsic pathway Added DEFINITION A pathway of blood coagulation that occurs during the clotting of platelet-poor plasma, in which activation of factor X to factor Xa is effected by the combination of factor IXa + factor VIIIa + calcium ion + phospholipid.
2002-11-27 GO:0005555 blood group antigen Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0001568 blood vessel development Added DEFINITION Development of vasculature carrying blood.
2002-11-27 GO:0045431 flavonol synthase activity Added DEFINITION Catalysis of the alpha-ketoglutarate-dependent oxidation of dihydroflavonols to flavonols.
2002-11-27 GO:0000128 flocculation Added DEFINITION Non-sexual aggregation of single-celled organisms in culture.
2002-11-27 GO:0000501 flocculation via cell wall protein-carbohydrate interaction Added DEFINITION Mannose sensitive, non sexual aggregation of cells mediated by protein-carbohydrate (flocculin-mannan) interaction present in the cell wall. This process is pH and calcium dependent and reversible.
2002-11-27 GO:0009908 flower development Added DEFINITION The development of reproductive structures in a plant beginning with the transition of the vegetative shoot apex into a reproductive apex.
2002-11-27 GO:0046234 fluorene biosynthetic process Added DEFINITION OBSOLETE. The synthesis from simpler components of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
2002-11-27 GO:0019429 fluorene catabolic process Added DEFINITION The breakdown into simpler components of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
2002-11-27 GO:0018917 fluorene metabolic process Added DEFINITION The chemical reactions and physical changes involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
2002-11-27 GO:0003919 FMN adenylyltransferase activity Added DEFINITION Catalysis of the reaction: ATP + FMN = diphosphate + FAD.
2002-11-27 GO:0009398 FMN biosynthetic process Added DEFINITION The formation from simpler components of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
2002-11-27 GO:0046444 FMN metabolic process Added DEFINITION The chemical reactions and physical changes involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
2002-11-27 GO:0009396 folic acid-containing compound biosynthetic process Added DEFINITION The formation from simpler components of folic acid and its derivatives.
2002-11-27 GO:0005794 Golgi apparatus Added DEFINITION A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2002-11-27 GO:0005801 cis-Golgi network Added DEFINITION The convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
2002-11-27 GO:0000139 Golgi membrane Added DEFINITION The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
2002-11-27 GO:0030173 integral component of Golgi membrane Added DEFINITION An integral membrane protein found in membranes of the Golgi complex.
2002-11-27 GO:0007030 Golgi organization Added DEFINITION Assembly and maintenance of the Golgi apparatus.
2002-11-27 GO:0045053 protein retention in Golgi apparatus Added DEFINITION The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.
2002-11-27 GO:0006895 Golgi to endosome transport Added DEFINITION The directed movement of proteins from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
2002-11-27 GO:0006893 Golgi to plasma membrane transport Added DEFINITION The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
2002-11-27 GO:0006894 Golgi to secretory vesicle transport Added DEFINITION The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release.
2002-11-27 GO:0006896 Golgi to vacuole transport Added DEFINITION The directed movement of proteins from the Golgi to the vacuole.
2002-11-27 GO:0005802 trans-Golgi network Added DEFINITION The concave side of the Golgi apparatus, from which secretory vesicles emerge.
2002-11-27 GO:0017119 Golgi transport complex Updated DEFINITION A complex of proteins that, in vitro, stimulates intra-Golgi transport; a 13S complex, about 800 kDa in size and consists of at least five polypeptides. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p).
2002-11-27 GO:0005798 Golgi-associated vesicle Added DEFINITION Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
2002-11-27 GO:0030142 Golgi to ER transport vesicle Added DEFINITION A vesicle that mediates transport from the Golgi to the endoplasmic reticulum.
2002-11-27 GO:0012508 Golgi to ER transport vesicle membrane Added DEFINITION The membrane surrounding a vesicle transporting substances from the Golgi to the ER.
2002-11-27 GO:0005808 Golgi-plasma membrane transport vesicle Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0005809 Golgi-vacuole transport vesicle Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0008406 gonad development Added DEFINITION The development of an animal organ that produces gametes; in some species it also produces hormones.
2002-11-27 GO:0004898 gp130 Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0006506 GPI anchor biosynthetic process Added DEFINITION The formation from simpler components of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
2002-11-27 GO:0018270 GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018265 GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018266 GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018267 GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018268 GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0018269 GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine Added DEFINITION The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
2002-11-27 GO:0006505 GPI anchor metabolic process Updated DEFINITION The chemical reactions and physical changes involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate moiety, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
2002-11-27 GO:0042080 GPI/GSI anchor biosynthetic process Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0019985 translesion synthesis Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is mutagenic.
2002-11-27 GO:0000251 C-14 sterol reductase activity Updated DEFINITION Catalysis of the reduction of the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol.
2002-11-27 GO:0000249 C-22 sterol desaturase activity Updated DEFINITION Catalysis of the formation of the C-22(23) double bond in the sterol side chain.
2002-11-27 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity Updated DEFINITION Catalysis of the removal of the 3-alpha hydrogen from the 3-ketocarboxylic acid sterol intermediate, resulting in the decarboxylation of the 3-ketocarboxylic acid: acts in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol in ergosterol biosynthesis.
2002-11-27 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity Added DEFINITION Catalysis of the reaction: 2 ATP + L-glutamine + carbon dioxide + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
2002-11-27 GO:0005951 carbamoyl-phosphate synthase complex Added DEFINITION An enzyme complex that exists in monomer, dimer, and higher oligomeric forms. Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.
2002-11-27 GO:0046231 carbazole biosynthetic process Added DEFINITION OBSOLETE. The formation from simpler components of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
2002-11-27 GO:0046232 carbazole catabolic process Added DEFINITION The breakdown into simpler components of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
2002-11-27 GO:0006458 'de novo' protein folding Added DEFINITION Processes that assist the folding of a nascent peptide chain into its correct tertiary structure.
2002-11-27 GO:0046211 (+)-camphor biosynthetic process Added DEFINITION The formation from simpler components of (+)-camphor, a bicyclic monoterpene ketone.
2002-11-27 GO:0019383 (+)-camphor catabolic process Added DEFINITION The breakdown into simpler components of (+)-camphor, a bicyclic monoterpene ketone.
2002-11-27 GO:0018882 (+)-camphor metabolic process Added DEFINITION The chemical reactions and physical changes involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.
2002-11-27 GO:0046550 (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine Added DEFINITION The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7.
2002-11-27 GO:0019084 middle viral transcription Added DEFINITION The second round of viral gene transcription; most genes transcribed in this round are necessary for genome replication.
2002-11-27 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide.
2002-11-27 GO:0019599 (R)-4-hydroxymandelate catabolic process Added DEFINITION The breakdown into simpler components of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.
2002-11-27 GO:0046431 (R)-4-hydroxymandelate metabolic process Added DEFINITION The chemical reactions and physical changes involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).
2002-11-27 GO:0019147 (R)-aminopropanol dehydrogenase activity Added DEFINITION Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + NADH + H+.
2002-11-27 GO:0015746 citrate transport Added DEFINITION Directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, outside, or within a cell.
2002-11-27 GO:0015137 citrate transmembrane transporter activity Added DEFINITION Enables the directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, outside, or within a cell.
2002-11-27 GO:0019240 citrulline biosynthetic process Added DEFINITION The formation from simpler components of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
2002-11-27 GO:0019241 citrulline catabolic process Added DEFINITION The breakdown into simpler components of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
2002-11-27 GO:0000052 citrulline metabolic process Added DEFINITION The chemical reactions and physical changes involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
2002-11-27 GO:0008816 citryl-CoA lyase activity Added DEFINITION Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.
2002-11-27 GO:0001620 class A orphan receptor activity Added DEFINITION A G-protein coupled receptor that is structurally and functionally related to the rhodopsin receptor, but whose ligand is unknown.
2002-11-27 GO:0001645 class C orphan receptor activity Added DEFINITION A G-protein coupled receptor that is structurally/functionally related to the metabotropic glutamate receptors and binds an unknown ligand.
2002-11-27 GO:0009466 class I cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0003820 class I major histocompatibility complex antigen Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009469 class II cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0003821 class II major histocompatibility complex antigen Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009470 class IIa cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009480 class IIb cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009471 class III cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009476 class IV cytochrome c Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0003813 classical-complement-pathway C3/C5 convertase activity Added DEFINITION Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b.
2002-11-27 GO:0005906 clathrin adaptor Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0030131 clathrin adaptor complex Added DEFINITION A membrane adaptor complex that links clathrin to a membrane.
2002-11-27 GO:0030118 clathrin coat Added DEFINITION A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.
2002-11-27 GO:0030132 clathrin coat of coated pit Added DEFINITION The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.
2002-11-27 GO:0030128 clathrin coat of endocytic vesicle Added DEFINITION A clathrin coat found on an endocytic vesicle.
2002-11-27 GO:0030129 clathrin coat of synaptic vesicle Added DEFINITION A clathrin coat found on a synaptic vesicle.
2002-11-27 GO:0030130 clathrin coat of trans-Golgi network vesicle Added DEFINITION A clathrin coat found on a vesicle of the trans-Golgi network.
2002-11-27 GO:0030125 clathrin vesicle coat Added DEFINITION A clathrin coat found on a vesicle.
2002-11-27 GO:0045334 clathrin-coated endocytic vesicle Added DEFINITION A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.
2002-11-27 GO:0045336 clathrin-coated phagocytic vesicle Added DEFINITION A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
2002-11-27 GO:0030136 clathrin-coated vesicle Added DEFINITION A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
2002-11-27 GO:0030365 cleavage stimulation factor activity Added DEFINITION A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide.
2002-11-27 GO:0030364 cleavage and polyadenylylation specificity factor activity Added DEFINITION A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions.
2002-11-27 GO:0045163 clustering of voltage-gated potassium channels Added DEFINITION The process by which voltage gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.
2002-11-27 GO:0018252 peptide cross-linking via L-seryl-5-imidazolinone glycine Added DEFINITION The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue N, a serine, to the alpha-amino nitrogen of residue N+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue N+1. This cross-linking is coupled with a dehydrogenation of residue N+1 to form a double bond between the alpha and beta carbons. See GO:0018251.
2002-11-27 GO:0009374 biotin binding Added DEFINITION Interacting selectively and stoichiometrically with biotin (cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2002-11-27 GO:0009102 biotin biosynthetic process Added DEFINITION The formation from simpler components of biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid.
2002-11-27 GO:0004075 biotin carboxylase activity Added DEFINITION Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + carbon dioxide = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
2002-11-27 GO:0009343 biotin carboxylase complex Added DEFINITION An enzyme that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide.
2002-11-27 GO:0042367 biotin catabolic process Added DEFINITION The breakdown into simpler components of biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid.
2002-11-27 GO:0006768 biotin metabolic process Added DEFINITION The chemical reactions and physical changes involving biotin, cis-tetrahydro-2-oxothieno[3,4-d]imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2002-11-27 GO:0004076 biotin synthase activity Added DEFINITION Catalysis of the reaction: dethiobiotin + sulfur = biotin.
2002-11-27 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP forming)] = AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase (ADP forming)].
2002-11-27 GO:0004078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)].
2002-11-27 GO:0004079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[methylmalonyl-CoA:pyruvate carboxyltransferase] = AMP + diphosphate + [methylmalonyl-CoA:pyruvate carboxyltransferase].
2002-11-27 GO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity Added DEFINITION Catalysis of the reaction: ATP + biotin + apo-[propanoyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [propanoyl-CoA:carbon-dioxide ligase (ADP-forming)].
2002-11-27 GO:0019018 bipartite viral genome Added DEFINITION A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.
2002-11-27 GO:0018687 biphenyl 2,3-dioxygenase activity Added DEFINITION Catalysis of the conversion of biphenyl to (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol with the oxidation of NADH to NAD; requires Fe[2+].
2002-11-27 GO:0000286 alanine dehydrogenase activity Added DEFINITION Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + ammonia + NADH + H+.
2002-11-27 GO:0006522 alanine metabolic process Added DEFINITION The chemical reactions and physical changes involving alanine, 2-aminopropanoic acid.
2002-11-27 GO:0008784 alanine racemase activity Added DEFINITION Catalysis of the reaction: L-alanine = D-alanine.
2002-11-27 GO:0018086 alanine racemization Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0015808 L-alanine transport Added DEFINITION The directed movement of alanine, 2-aminopropanoic acid, into, out of, or within a cell.
2002-11-27 GO:0015180 L-alanine transmembrane transporter activity Added DEFINITION Enables the directed movement of alanine, 2-aminopropanoic acid, into, out of, or within a cell.
2002-11-27 GO:0008453 alanine-glyoxylate transaminase activity Added DEFINITION Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.
2002-11-27 GO:0045107 intermediate filament polymerization Added DEFINITION Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.
2002-11-27 GO:0045105 intermediate filament polymerization or depolymerization Added DEFINITION Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.
2002-11-27 GO:0045103 intermediate filament-based process Added DEFINITION Any cellular process that depends upon or alters the intermediate filament cytoskeleton (that part of the cytoskeleton comprising intermediate filaments and their associated proteins).
2002-11-27 GO:0009898 cytoplasmic side of plasma membrane Added DEFINITION The side of the plasma membrane that faces the cytoplasm.
2002-11-27 GO:0005707 interphase chromosome Added DEFINITION A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently.
2002-11-27 GO:0001560 regulation of cell growth by extracellular stimulus Updated DEFINITION The process where external signals regulate whether a cell increases its mass (size).
2002-11-27 GO:0001559 regulation of cell growth by detection of nuclear:cytoplasmic ratio Updated DEFINITION The process where the size of the nucleus with respect to its cytoplasm signals the cell to grow or stop growing.
2002-11-27 GO:0004232 interstitial collagenase activity Added DEFINITION Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.
2002-11-27 GO:0006891 intra-Golgi vesicle-mediated transport Added DEFINITION The directed movement of proteins within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).
2002-11-27 GO:0005622 intracellular Added DEFINITION The living contents of a cell; the matter contained within the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
2002-11-27 GO:0006973 intracellular accumulation of glycerol Added DEFINITION The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the perception of a hyperosmotic environment.
2002-11-27 GO:0046691 intracellular canaliculus Added DEFINITION A narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates.
2002-11-27 GO:0006886 intracellular protein transport Updated DEFINITION The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
2002-11-27 GO:0030522 intracellular receptor signaling pathway Added DEFINITION A signaling pathway initiated by a ligand entering the target cell, where it binds to an intracellular receptor.
2002-11-27 GO:0005241 inward rectifier channel Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0004447 iodide peroxidase activity Added DEFINITION Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O.
2002-11-27 GO:0015705 iodide transport Added DEFINITION Directed movement of iodide into, outside, or within a cell.
2002-11-27 GO:0005216 ion channel activity Added DEFINITION Allows the regulatable energy-independent passage of ions across a lipid bilayer down a concentration gradient.
2002-11-27 GO:0045161 neuronal ion channel clustering Added DEFINITION The process by which voltage-gated sodium and potassium become localized to distinct subcellular domains. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
2002-11-27 GO:0015075 ion transmembrane transporter activity Added DEFINITION Enables the directed movement of charged atoms or small charged molecules into, out of, or within a cell.
2002-11-27 GO:0018922 iprodione metabolic process Added DEFINITION The chemical reactions and physical changes involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium).
2002-11-27 GO:0018290 iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide Added DEFINITION The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.
2002-11-27 GO:0009785 blue light signaling pathway Added DEFINITION The process by which blue light is converted into a cellular response.
2002-11-27 GO:0030509 BMP signaling pathway Added DEFINITION Signaling pathway involving receptors for any of the BMP (bone morphogenetic protein) family.
2002-11-27 GO:0040032 post-embryonic body morphogenesis Added DEFINITION Formation and development of organized structures of the post-embryonic soma.
2002-11-27 GO:0030282 bone mineralization Added DEFINITION The deposition of calcium phosphate in bone tissue.
2002-11-27 GO:0045453 bone resorption Added DEFINITION The process by which bone tissue is lost; it can be through physiologic or pathologic means.
2002-11-27 GO:0046714 borate binding Added DEFINITION Interacting selectively and stoichiometrically with boron, the group 13 element with properties which are borderline between metals and non-metals.
2002-11-27 GO:0046713 borate transport Added DEFINITION The directed movement of boron into, out of, or within a cell. Boron is a group 13 element, with properties which are borderline between metals and non-metals.
2002-11-27 GO:0046715 borate transmembrane transporter activity Added DEFINITION Catalysis of the transport of boron across a membrane against the concentration gradient.
2002-11-27 GO:0005734 box C + D snoRNP protein Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0005735 box H + ACA snoRNP protein Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0009082 branched-chain amino acid biosynthetic process Added DEFINITION The formation from simpler components of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2002-11-27 GO:0009083 branched-chain amino acid catabolic process Added DEFINITION The breakdown into simpler components of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2002-11-27 GO:0009081 branched-chain amino acid metabolic process Added DEFINITION The chemical reactions and physical changes involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2002-11-27 GO:0015803 branched-chain amino acid transport Added DEFINITION The directed movement of branched-chain aliphatic amino acids, amino acids with branched carbon skeleton without rings, into, out of, or within a cell.
2002-11-27 GO:0015658 branched-chain amino acid transmembrane transporter activity Added DEFINITION Enables the directed movement of branched-chain aliphatic amino acids, amino acids with branched carbon skeleton without rings, into, out of, or within a cell.
2002-11-27 GO:0004084 branched-chain-amino-acid transaminase activity Added DEFINITION Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
2002-11-27 GO:0016132 brassinosteroid biosynthetic process Added DEFINITION The formation from simpler components of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
2002-11-27 GO:0016133 brassinosteroid catabolic process Added DEFINITION The breakdown into simpler components of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
2002-11-27 GO:0009742 brassinosteroid mediated signaling pathway Added DEFINITION Signal transduction pathway mediated by the perception of brassinosteroid.
2002-11-27 GO:0016131 brassinosteroid metabolic process Added DEFINITION The chemical reactions and physical changes involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
2002-11-27 GO:0019806 bromide peroxidase activity Added DEFINITION Catalysis of the reaction: 2 RH + 2 bromide + hydrogen peroxide = 2 RBr + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.
2002-11-27 GO:0018881 bromoxynil metabolic process Added DEFINITION The chemical reactions and physical changes involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants.
2002-11-27 GO:0018761 bromoxynil nitrilase activity Added DEFINITION Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxy-benzoate + NH3. Involved in the bacterial degradation of the herbicide bromoxynil.
2002-11-27 GO:0005933 cellular bud Added DEFINITION A daughter cell of an organism that reproduces by budding; formed by pinching off part of the parent cell.
2002-11-27 GO:0005935 cellular bud neck Added DEFINITION The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
2002-11-27 GO:0007115 bud site selection/establishment of cell polarity (sensu Saccharomyces) Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0005934 cellular bud tip Added DEFINITION The end of a bud distal to the site of attachment to the mother cell.
2002-11-27 GO:0007114 cell budding Added DEFINITION A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
2002-11-27 GO:0019650 glucose catabolic process to butanediol Added DEFINITION An anaerobic process in which glucose is fermented, with the production of 2,3-butanediol and other substances; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.
2002-11-27 GO:0046358 butyrate biosynthetic process Added DEFINITION The formation from simpler components of butyrate, the anion of butyric acid.
2002-11-27 GO:0046359 butyrate catabolic process Added DEFINITION The breakdown into simpler components of butyrate, the anion of butyric acid.
2002-11-27 GO:0030645 glucose catabolic process to butyrate Added DEFINITION An anaerobic process in which glucose is fermented, with the production of acetic acid, butyric acid, carbon dioxide, and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.
2002-11-27 GO:0019605 butyrate metabolic process Added DEFINITION The chemical reactions and physical changes involving butyrate, the anion of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.
2002-11-27 GO:0018734 butyrolactone hydrolase activity Added DEFINITION Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.
2002-11-27 GO:0004085 butyryl-CoA dehydrogenase activity Added DEFINITION Catalysis of the reaction: butanoyl-CoA + ETF = 2-butenoyl-CoA + reduced ETF.
2002-11-27 GO:0015727 lactate transport Added DEFINITION Directed movement of lactate into, outside, or within a cell.
2002-11-27 GO:0007595 lactation Added DEFINITION The secretion of milk by the mammary gland.
2002-11-27 GO:0046573 lactonohydrolase activity Added DEFINITION Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.
2002-11-27 GO:0016686 lactoperoxidase activity Added DEFINITION Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
2002-11-27 GO:0030395 lactose binding Added DEFINITION Interacting selectively and stoichiometrically with lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.
2002-11-27 GO:0005989 lactose biosynthetic process Added DEFINITION The formation from simpler components of lactose, the disaccharide galactopyranosyl-glucose.
2002-11-27 GO:0005990 lactose catabolic process Added DEFINITION The breakdown into simpler components of lactose, the disaccharide galactopyranosyl-glucose.
2002-11-27 GO:0019512 lactose catabolic process via tagatose-6-phosphate Added DEFINITION The breakdown into simpler components of lactose, via the intermediate tagatose-6-phosphate.
2002-11-27 GO:0019515 lactose catabolic process via UDP-galactose Added DEFINITION The breakdown into simpler components of lactose, via the intermediate UDP-galactose.
2002-11-27 GO:0019513 lactose catabolic process, using glucoside 3-dehydrogenase Added DEFINITION The breakdown of lactose into simpler components, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13).
2002-11-27 GO:0005988 lactose metabolic process Added DEFINITION The chemical reactions and physical changes involving lactose, the disaccharide galactopyranosyl-glucose.
2002-11-27 GO:0004461 lactose synthase activity Added DEFINITION Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.
2002-11-27 GO:0030027 lamellipodium Updated DEFINITION A thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.
2002-11-27 GO:0001572 lactosylceramide biosynthetic process Added DEFINITION The formation from simpler components of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
2002-11-27 GO:0046478 lactosylceramide metabolic process Added DEFINITION The chemical reactions and physical changes involving lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
2002-11-27 GO:0018819 lactoyl-CoA dehydratase activity Added DEFINITION Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.
2002-11-27 GO:0004462 lactoylglutathione lyase activity Added DEFINITION Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
2002-11-27 GO:0030032 lamellipodium assembly Updated DEFINITION Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
2002-11-27 GO:0005521 lamin binding Added DEFINITION Interacting selectively and stoichiometrically with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
2002-11-27 GO:0005606 laminin-1 complex Updated DEFINITION Laminins are glycoproteins that are major constituents of the basement membrane of cells. Laminins are trimeric molecules; laminin-1 is an alpha1 beta1 gamma1 trimer.
2002-11-27 GO:0005607 laminin-2 complex Updated DEFINITION Laminins are glycoproteins that are major constituents of the basement membrane of cells. Laminins are trimeric molecules; laminin-2 is an alpha2, beta1 gamma1 trimer.
2002-11-27 GO:0005608 laminin-3 complex Updated DEFINITION Laminins are glycoproteins that are major constituents of the basement membrane of cells. Laminins are trimeric molecules; laminin-3 is an alpha1 beta2 gamma1 trimer.
2002-11-27 GO:0018264 isopeptide cross-linking via N-(L-isoaspartyl)-glycine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to form a N-(L-isoaspartyl)-glycine cross-link.
2002-11-27 GO:0018263 isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine forming N-(L-isoaspartyl)-L-cysteine.
2002-11-27 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine forming N6-(L-isoglutamyl)-L-lysine.
2002-11-27 GO:0018276 isopeptide cross-linking via N6-glycyl-L-lysine Added DEFINITION The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to form a N6-glycyl-L-lysine cross-link.
2002-11-27 GO:0018458 isopiperitenol dehydrogenase activity Added DEFINITION Catalysis of the reaction: (-)-trans-isopiperitenol + NAD+ = (-)-isopiperitenone + NADH + H+.
2002-11-27 GO:0008299 isoprenoid biosynthetic process Added DEFINITION The formation from simpler components of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2002-11-27 GO:0045162 clustering of voltage-gated sodium channels Added DEFINITION The process by which voltage gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.
2002-11-27 GO:0019597 (R)-mandelate catabolic process to benzoate Added DEFINITION The breakdown of (R)-mandelate into simpler components, including benzoate.
2002-11-27 GO:0019598 (R)-mandelate catabolic process to catechol Added DEFINITION The breakdown of (R)-mandelate into simpler components, including catechol.
2002-11-27 GO:0000721 (R,R)-butanediol dehydrogenase activity Added DEFINITION Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+.
2002-11-27 GO:0003973 (S)-2-hydroxy-acid oxidase activity Added DEFINITION Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.
2002-11-27 GO:0042188 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process Added DEFINITION The breakdown into simpler components of 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2002-11-27 GO:0018977 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
2002-11-27 GO:0018976 1,2,3-tribromopropane metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.
2002-11-27 GO:0018911 1,2,4-trichlorobenzene metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.
2002-11-27 GO:0046509 1,2-diacylglycerol 3-beta-galactosyltransferase activity Added DEFINITION Catalysis of the reaction: UDPgalactose + 1,2-diacylglycerol = UDP + 3-beta-D-galactosyl-1,2-diacylglycerol.
2002-11-27 GO:0019260 1,2-dichloroethane catabolic process Added DEFINITION The breakdown into simpler components of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
2002-11-27 GO:0018899 1,2-dichloroethane metabolic process Added DEFINITION The chemical reactions and physical changes involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
2002-11-27 GO:0018505 cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity Added DEFINITION Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.
2002-11-27 GO:0018521 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity Added DEFINITION Catalysis of the reaction: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ = 3-methylcatechol + NADH + H+ + carbon dioxide.
2002-11-27 GO:0018718 1,2-dihydroxy-phenanthrene glycosyltransferase activity Added DEFINITION Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDPglucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.
2002-11-27 GO:0003843 1,3-beta-D-glucan synthase activity Added DEFINITION Catalysis of the reaction: UDP-glucose + (1,3)-beta-D-glucosyl(N) = UDP + (1,3)-beta-D-glucosyl(N+1).
2002-11-27 GO:0019564 aerobic glycerol catabolic process Added DEFINITION The breakdown into simpler components of glycerol, 1,2,3-propanetriol, in the presence of oxygen.
2002-11-27 GO:0018935 aerobic nitrilotriacetate metabolic process Added DEFINITION The chemical reactions and physical changes involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen.
2002-11-27 GO:0018946 aerobic organosilicon metabolic process Added DEFINITION The chemical reactions and physical changes involving organosilicones, organic compounds that contain silicone, in the presence of oxygen.
2002-11-27 GO:0046190 aerobic phenol-containing compound biosynthetic process Added DEFINITION The formation from simpler components of phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
2002-11-27 GO:0046191 aerobic phenol-containing compound catabolic process Added DEFINITION The breakdown into simpler components of phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
2002-11-27 GO:0018959 aerobic phenol-containing compound metabolic process Added DEFINITION The chemical reactions and physical changes involving phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
2002-11-27 GO:0009454 aerotaxis Added DEFINITION The movement of a motile cell in response to atmospheric oxygen.
2002-11-27 GO:0045122 aflatoxin biosynthetic process Added DEFINITION The formation from simpler components of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
2002-11-27 GO:0046223 aflatoxin catabolic process Added DEFINITION The breakdown into simpler components of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
2002-11-27 GO:0046222 aflatoxin metabolic process Added DEFINITION The chemical reactions and physical changes involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
2002-11-27 GO:0007334 agglutination (sensu Saccharomyces) Added DEFINITION Aggregation or adhesion of the haploid mating type cells (a and alpha cells) prior to mating via complementary cell surface glycoproteins, a-agglutinin and alpha-agglutinin.
2002-11-27 GO:0007568 aging Added DEFINITION The inherent decline over time, from the optimal fertility and viability of early maturity, that culminates in death and may be preceded by other indications, such as sterility.
2002-11-27 GO:0007578 aging dependent sterility (sensu Saccharomyces) Added DEFINITION A haploid's inability to mate due to the loss of silencing at the mating type loci, resulting in expression of both of the normally silent mating type cassettes.
2002-11-27 GO:0008783 agmatinase activity Added DEFINITION Catalysis of the reaction: agmatine + H2O = putrescine + urea.
2002-11-27 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity Added DEFINITION Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
2002-11-27 GO:0006523 alanine biosynthetic process Added DEFINITION The formation from simpler components of alanine, 2-aminopropanoic acid.
2002-11-27 GO:0019272 L-alanine biosynthetic process from pyruvate Added DEFINITION The formation of alanine from simpler components, including pyruvate.
2002-11-27 GO:0019273 L-alanine biosynthetic process via ornithine Added DEFINITION The formation from simpler components of alanine, via the intermediate ornithine.
2002-11-27 GO:0006524 alanine catabolic process Added DEFINITION The breakdown into simpler components of alanine, 2-aminopropanoic acid.
2002-11-27 GO:0019481 L-alanine catabolic process, by transamination Added DEFINITION The breakdown into simpler components of alanine by transamination.
2002-11-27 GO:0004166 dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.
2002-11-27 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity Added DEFINITION Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
2002-11-27 GO:0004581 dolichyl-phosphate beta-glucosyltransferase activity Added DEFINITION Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.
2002-11-27 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity Added DEFINITION Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide.
2002-11-27 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity Added DEFINITION Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.
2002-11-27 GO:0046566 DOPA dioxygenase activity Added DEFINITION Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid.
2002-11-27 GO:0004167 dopachrome isomerase activity Added DEFINITION Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.
2002-11-27 GO:0042416 dopamine biosynthetic process Added DEFINITION The formation from simpler components of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0006585 dopamine biosynthetic process from tyrosine Added DEFINITION The formation of dopamine, a catecholamine neurotransmitter, from tyrosine (3,4-dihydroxy-L-phenylalanine) via the aromatic-L-amino-acid decarboxylase (EC:4.1.1.28).
2002-11-27 GO:0042420 dopamine catabolic process Added DEFINITION The breakdown into simpler components of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0001590 dopamine D1 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D1 receptors.
2002-11-27 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs Added DEFINITION A G-protein coupled receptor that binds the neurotransmitter dopamine and activates adenylate cyclase via coupling to Gs.
2002-11-27 GO:0001670 dopamine D2 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D4 receptors.
2002-11-27 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go Added DEFINITION A G-protein coupled receptor that binds the neurotransmitter dopamine and inhibits adenylate cyclase via coupling to Gi/Go.
2002-11-27 GO:0001592 dopamine D3 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D3 receptors.
2002-11-27 GO:0001593 dopamine D4 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D4 receptors.
2002-11-27 GO:0001589 dopamine D5 receptor activity Added DEFINITION A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D5 receptors.
2002-11-27 GO:0042417 dopamine metabolic process Added DEFINITION The chemical reactions and physical changes involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0004952 dopamine neurotransmitter receptor activity Added DEFINITION A G-protein coupled receptor that uses the neurotransmitter dopamine as a ligand.
2002-11-27 GO:0015872 dopamine transport Added DEFINITION The directed movement of dopamine into, out of, or within a cell. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
2002-11-27 GO:0009397 folic acid-containing compound catabolic process Added DEFINITION The breakdown into simpler components of folic acid and its derivatives.
2002-11-27 GO:0006760 folic acid-containing compound metabolic process Added DEFINITION The chemical reactions and physical changes involving folic acid and its derivatives.
2002-11-27 GO:0005542 folic acid binding Added DEFINITION Interacting selectively and stoichiometrically with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
2002-11-27 GO:0046656 folic acid biosynthetic process Added DEFINITION The formation from simpler components of folic acid, pteroylglutamic acid.
2002-11-27 GO:0046657 folic acid catabolic process Added DEFINITION The breakdown into simpler components of folic acid, pteroylglutamic acid.
2002-11-27 GO:0046655 folic acid metabolic process Added DEFINITION The chemical reactions and physical changes involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
2002-11-27 GO:0016913 follicle-stimulating hormone activity Added DEFINITION A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland.
2002-11-27 GO:0004326 tetrahydrofolylpolyglutamate synthase activity Added DEFINITION Catalysis of the reaction: ATP + tetrahydrofolyl-[Glu](n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-[Glu](n+1).
2002-11-27 GO:0020020 food vacuole Added DEFINITION Vacuole within a parasite used for digestion of the host cell cytoplasm.
2002-11-27 GO:0005506 iron ion binding Added DEFINITION Interacting selectively and stoichiometrically with iron (Fe).
2002-11-27 GO:0006879 cellular iron ion homeostasis Added DEFINITION The regulation of the levels, transport, and metabolism of iron ions within a cell or between a cell and its external environment.
2002-11-27 GO:0016948 iron hydrogenase activity Updated DEFINITION Iron-sulfur-containing hydrogenase ([Fe] hydrogenase) with two ferredoxin-type (4Fe-4S) clusters and an atypical iron-sulfur center believed to be involved in the activation of H2. The [Fe] hydrogenase has the highest specific activity in the evolution and consumption of hydrogen and in the proton-deuterium exchange reaction and this enzyme is the most sensitive to CO and NO2-.
2002-11-27 GO:0018306 iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide Added DEFINITION The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.
2002-11-27 GO:0018300 iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide Added DEFINITION OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide.
2002-11-27 GO:0018441 iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide Added DEFINITION The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.
2002-11-27 GO:0019709 iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide Added DEFINITION The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.
2002-11-27 GO:0018285 iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide Added DEFINITION The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.
2002-11-27 GO:0018288 iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide Added DEFINITION The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.
2002-11-27 GO:0019477 L-lysine catabolic process Added DEFINITION The breakdown into simpler components of L-lysine, the levorotatory isomer of (S)-2,6-diaminohexanoic acid.
2002-11-27 GO:0019475 L-lysine catabolic process to acetate Added DEFINITION The breakdown of L-lysine into simpler components, including acetate.
2002-11-27 GO:0019474 L-lysine catabolic process to acetyl-CoA Added DEFINITION The breakdown of L-lysine into simpler components, including acetyl-CoA.
2002-11-27 GO:0019473 L-lysine catabolic process to glutarate, by acetylation Added DEFINITION The breakdown of L-lysine into simpler components, including glutarate, by acetylation.
2002-11-27 GO:0015661 L-lysine efflux transmembrane transporter activity Added DEFINITION Catalysis of the stereospecific transfer of L-lysine, 2,6-diaminohexanoic acid, across a biological membrane out of a cell.
2002-11-27 GO:0046440 L-lysine metabolic process Added DEFINITION The chemical reactions and physical changes involving L-lysine, the levorotatory isomer of (S)-2,6-diaminohexanoic acid.
2002-11-27 GO:0019324 L-lyxose metabolic process Added DEFINITION The chemical reactions and physical changes involving L-lyxose, the levorotatory isomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.
2002-11-27 GO:0030060 L-malate dehydrogenase activity Updated DEFINITION Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+. Also oxidizes some other 2-hydroxydicarboxylic acids.
2002-11-27 GO:0019680 L-methylmalonyl-CoA biosynthetic process Added DEFINITION The formation from simpler components of L-methylmalonyl-CoA, the levorotatory isomer of 2-carboxypropanoyl-CoA.
2002-11-27 GO:0046491 L-methylmalonyl-CoA metabolic process Added DEFINITION The chemical reactions and physical changes involving L-methylmalonyl-CoA, the levorotatory isomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.
2002-11-27 GO:0008740 L-rhamnose isomerase activity Added DEFINITION Catalysis of the reaction: L-rhamnose = L-rhamnulose.
2002-11-27 GO:0008741 ribulokinase activity Added DEFINITION Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.
2002-11-27 GO:0008742 L-ribulose-phosphate 4-epimerase activity Added DEFINITION Catalysis of the reaction: L-ribulose 5-phosphate = D-xylose 5-phosphate.
2002-11-27 GO:0003941 L-serine ammonia-lyase activity Added DEFINITION Catalysis of the reaction: L-serine = pyruvate + ammonia.
2002-11-27 GO:0019312 L-sorbose metabolic process Added DEFINITION The chemical reactions and physical changes involving sorbose, the levorotatory isomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.
2002-11-27 GO:0008743 L-threonine 3-dehydrogenase activity Added DEFINITION Catalysis of the reaction: L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH + H+.
2002-11-27 GO:0008744 L-xylulokinase activity Added DEFINITION Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate.
2002-11-27 GO:0008471 laccase activity Added DEFINITION Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.
2002-11-27 GO:0008911 lactaldehyde dehydrogenase activity Added DEFINITION Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.
2002-11-27 GO:0008912 lactaldehyde reductase activity Added DEFINITION Catalysis of the reaction: (R) [or (S)]-propane-1,2-diol + NAD+ = (R) [or (S)]-lactaldehyde + NADH + H+.
2002-11-27 GO:0000016 lactase activity Added DEFINITION Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.
2002-11-27 GO:0019249 lactate biosynthetic process Added DEFINITION The formation from simpler components of lactate, the anion of lactic acid.
2002-11-27 GO:0019244 lactate biosynthetic process from pyruvate Added DEFINITION The formation of lactate from simpler components, including pyruvate.
2002-11-27 GO:0004457 lactate dehydrogenase activity Added DEFINITION Catalysis of the oxidation of lactate to produce pyruvate.
2002-11-27 GO:0006089 lactate metabolic process Updated DEFINITION The chemical reactions and physical changes involving lactate, the anion of lactic acid.
2002-11-27 GO:0019247 lactate racemization Added DEFINITION Partial conversion of one lactate enantiomorph into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.
2002-11-27 GO:0004091 carboxylesterase activity Added DEFINITION Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion.
2002-11-27 GO:0046394 carboxylic acid biosynthetic process Added DEFINITION The formation from simpler components of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
2002-11-27 GO:0046395 carboxylic acid catabolic process Added DEFINITION The breakdown into simpler components of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
2002-11-27 GO:0019752 carboxylic acid metabolic process Added DEFINITION The chemical reactions and physical changes involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
2002-11-27 GO:0008806 carboxymethylenebutenolidase activity Added DEFINITION Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.
2002-11-27 GO:0004182 carboxypeptidase A activity Added DEFINITION Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid.
2002-11-27 GO:0004186 carboxypeptidase C activity Added DEFINITION Catalysis of the release of a C-terminal amino acid with a broad specificity.
2002-11-27 GO:0004187 carboxypeptidase D activity Added DEFINITION Catalysis of the preferential release of a C-terminal arginine or lysine residue.
2002-11-27 GO:0004183 carboxypeptidase E activity Added DEFINITION Catalysis of the reaction: peptidyl-L-lysine(or L-arginine) + H2O = peptide + L-lysine(or L-arginine).
2002-11-27 GO:0008807 carboxyvinyl-carboxyphosphonate phosphorylmutase activity Added DEFINITION Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + carbon dioxide.
2002-11-27 GO:0008808 cardiolipin synthase activity Added DEFINITION Catalysis of the condensation of two 3-phosphatidylglycerol molecules, by transferring the phosphatidyl group from one to the other, producing glycerol and diphosphatidyl glycerol.
2002-11-27 GO:0045329 carnitine biosynthetic process Added DEFINITION The formation from simpler components of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
2002-11-27 GO:0042413 carnitine catabolic process Added DEFINITION The breakdown into simpler components of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
2002-11-27 GO:0009437 carnitine metabolic process Added DEFINITION The chemical reactions and physical changes involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
2002-11-27 GO:0019254 carnitine metabolic process, CoA-linked Added DEFINITION The chemical reactions and physical changes involving carnitine, where metabolism is linked to CoA.
2002-11-27 GO:0004092 carnitine O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine.
2002-11-27 GO:0004093 carnitine O-acetyltransferase I activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine.
2002-11-27 GO:0004094 carnitine O-acetyltransferase II activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine.
2002-11-27 GO:0008458 carnitine O-octanoyltransferase activity Added DEFINITION Catalysis of the reaction: octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine.
2002-11-27 GO:0004095 carnitine O-palmitoyltransferase activity Added DEFINITION Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
2002-11-27 GO:0006853 carnitine shuttle Added DEFINITION The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane (GO:0005743) with unacylated carnitine.
2002-11-27 GO:0016719 carotene 7,8-desaturase activity Added DEFINITION Catalysis of the reaction: neurosporene + AH2 + O2 = lycopene + A + 2 H2O.
2002-11-27 GO:0000254 C-4 methylsterol oxidase activity Updated DEFINITION Catalysis of the oxidation of the 4-alpha methyl group of 4,4-dimethylzymosterol, the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol in ergosterol biosynthesis.
2002-11-27 GO:0000248 C-5 sterol desaturase activity Updated DEFINITION Catalysis of the introduction of a C-5 double bond in the B ring of ergosterol.
2002-11-27 GO:0000247 C-8 sterol isomerase activity Updated DEFINITION Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.
2002-11-27 GO:0016493 C-C chemokine receptor activity Added DEFINITION A chemokine receptor that functions primarily in mononuclear cells. The ligands do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
2002-11-27 GO:0018103 protein C-linked glycosylation Added DEFINITION The glycosylation of a peptidyl-amino acid residue at a C atom.
2002-11-27 GO:0018406 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan Added DEFINITION The glycosylation of a peptidyl-tryptophan residue by the attachment of alpha-mannopyranose to the indole ring.
2002-11-27 GO:0018034 C-terminal peptidyl-alanine amidation Added DEFINITION The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.
2002-11-27 GO:0009224 CMP biosynthetic process Added DEFINITION The formation from simpler components of CMP, cytidine monophosphate.
2002-11-27 GO:0006248 CMP catabolic process Added DEFINITION The breakdown into simpler components of CMP, cytidine monophosphate.
2002-11-27 GO:0046035 CMP metabolic process Added DEFINITION The chemical reactions and physical changes involving CMP, cytidine monophosphate.
2002-11-27 GO:0006055 CMP-N-acetylneuraminate biosynthetic process Added DEFINITION The formation from simpler components of CMP-N-acetylneuraminate, a compound of cytidine monophosphate and the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
2002-11-27 GO:0046381 CMP-N-acetylneuraminate metabolic process Added DEFINITION The chemical reactions and physical changes involving CMP-N-acetylneuraminate, a compound of cytidine monophosphate and the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
2002-11-27 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity Added DEFINITION Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.
2002-11-27 GO:0015782 CMP-N-acetylneuraminate transport Added DEFINITION The directed movement of CMP-sialic acid, a compound composed of sialic acid and cytidine monophosphate, into, out of, or within a cell.
2002-11-27 GO:0042151 nematocyst Added DEFINITION An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.
2002-11-27 GO:0006613 cotranslational protein targeting to membrane Added DEFINITION The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the ER lumen occurs in this manner.
2002-11-27 GO:0005905 coated pit Added DEFINITION An invagination of the cell membrane of many eukaryotic cells, concerned in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane. During endocytosis it is converted into a coated vesicle. The coat is of clathrin.
2002-11-27 GO:0030135 coated vesicle Added DEFINITION Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
2002-11-27 GO:0005799 coatomer Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity Added DEFINITION Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin.
2002-11-27 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity Added DEFINITION Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
2002-11-27 GO:0003887 DNA-directed DNA polymerase activity Updated DEFINITION Enzymes that catalyze the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template or primer.
2002-11-27 GO:0003899 DNA-directed RNA polymerase activity Added DEFINITION Catalysis of DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
2002-11-27 GO:0003900 DNA-directed RNA polymerase I activity Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
2002-11-27 GO:0003901 DNA-directed RNA polymerase II activity Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
2002-11-27 GO:0003902 DNA-directed RNA polymerase III activity Added DEFINITION Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
2002-11-27 GO:0018142 protein-DNA covalent cross-linking Added DEFINITION The formation of a covalent cross-link between DNA and a protein.
2002-11-27 GO:0018145 protein-DNA covalent cross-linking via peptidyl-serine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine.
2002-11-27 GO:0018164 protein-DNA covalent cross-linking via peptidyl-threonine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.
2002-11-27 GO:0045327 protein-DNA covalent cross-linking via peptidyl-tyrosine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue.
2002-11-27 GO:0045326 protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.
2002-11-27 GO:0018163 protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine Added DEFINITION The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.
2002-11-27 GO:0004165 dodecenoyl-CoA delta-isomerase activity Added DEFINITION Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA.
2002-11-27 GO:0018909 dodecyl sulfate metabolic process Added DEFINITION The chemical reactions and physical changes involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.
2002-11-27 GO:0019408 dolichol biosynthetic process Added DEFINITION The formation from simpler components of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
2002-11-27 GO:0004168 dolichol kinase activity Added DEFINITION Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.
2002-11-27 GO:0019348 dolichol metabolic process Added DEFINITION The chemical reactions and physical changes involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
2002-11-27 GO:0006489 dolichyl diphosphate biosynthetic process Added DEFINITION The formation from simpler components of dolichyl diphosphate, a diphosphorylated dolichol derivative.
2002-11-27 GO:0046465 dolichyl diphosphate metabolic process Added DEFINITION The chemical reactions and physical changes involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.
2002-11-27 GO:0042283 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Added DEFINITION The addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
2002-11-27 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity Added DEFINITION The addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
2002-11-27 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity Added DEFINITION Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
2002-11-27 GO:0006876 cellular cadmium ion homeostasis Added DEFINITION The regulation of the levels, transport, and metabolism of cadmium ions within a cell or between a cell and its external environment.
2002-11-27 GO:0019830 cadmium sensitivity/resistance Added DEFINITION OBSOLETE (was not defined before being made obsolete).
2002-11-27 GO:0015434 cadmium-transporting ATPase activity Updated DEFINITION An ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that exports some heavy metals, especially cadmium, from the cytosol into the vacuole; does not undergo phosphorylation during the transport process.
2002-11-27 GO:0042409 caffeoyl-CoA O-methyltransferase activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.
2002-11-27 GO:0015030 Cajal body Updated DEFINITION A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Gall argues that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
2002-11-27 GO:0004813 alanine-tRNA ligase activity Added DEFINITION Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
2002-11-27 GO:0046165 alcohol biosynthetic process Added DEFINITION The formation from simpler components of alcohols, any of a class of alkyl compounds containing a hydroxyl group.
2002-11-27 GO:0046164 alcohol catabolic process Added DEFINITION The breakdown into simpler components of alcohols, any of a class of alkyl compounds containing a hydroxyl group.
2002-11-27 GO:0004022 alcohol dehydrogenase (NAD) activity Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0018468 alcohol dehydrogenase (acceptor) activity Added DEFINITION Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor.
2002-11-27 GO:0008106 alcohol dehydrogenase (NADP+) activity Added DEFINITION Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
2002-11-27 GO:0004025 alcohol dehydrogenase activity, iron-dependent Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0004023 alcohol dehydrogenase activity, metal ion-independent Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0004024 alcohol dehydrogenase activity, zinc-dependent Added DEFINITION Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2002-11-27 GO:0006066 alcohol metabolic process Added DEFINITION The chemical reactions and physical changes involving alcohols, any of a class of alkyl compounds containing a hydroxyl group.
2002-11-27 GO:0004026 alcohol O-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester.
2002-11-27 GO:0004027 alcohol sulfotransferase activity Added DEFINITION Catalysis of the reaction: 3'-phosphoadenylylsulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
2002-11-27 GO:0019578 aldaric acid biosynthetic process Added DEFINITION The formation from simpler components of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
2002-11-27 GO:0019579 aldaric acid catabolic process Added DEFINITION The breakdown into simpler components of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
2002-11-27 GO:0019577 aldaric acid metabolic process Added DEFINITION The chemical reactions and physical changes involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
2002-11-27 GO:0046184 aldehyde biosynthetic process Added DEFINITION The formation from simpler components of aldehydes, any organic compound with the formula R-CH=O.
2002-11-27 GO:0046185 aldehyde catabolic process Added DEFINITION The breakdown into simpler components of aldehydes, any organic compound with the formula R-CH=O.
2002-11-27 GO:0009924 octadecanal decarbonylase activity Added DEFINITION Catalysis of the reaction: octadecanal = heptadecane + CO.
2002-11-27 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity Added DEFINITION Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2e- + 3-chloroacrylic acid.
2002-11-27 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity Added DEFINITION Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.
2002-11-27 GO:0008300 isoprenoid catabolic process Added DEFINITION The breakdown into simpler components of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2002-11-27 GO:0006720 isoprenoid metabolic process Updated DEFINITION The chemical reactions and physical changes involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
2002-11-27 GO:0007119 budding cell isotropic bud growth Added DEFINITION Unlocalized bud growth such that the entire surface of the bud expands evenly.
2002-11-27 GO:0045190 isotype switching Added DEFINITION The switching between different isotypes of a molecule. For example, the switch of immunoglobulin isotype that occurs as the immune response progresses is IgM to IgG. This involves only the constant region of the heavy chains, the light chain and variable regions of the heavy chain remaining the same and involves the switch regions, upstream (on the 5' side) of the constant region genes, at which recombination occurs. Similarly, IgM and IgD with the same variable region of the heavy chain, but with different heavy chain constant regions, seem to coexist on the surface of some lymphocytes.
2002-11-27 GO:0046293 formaldehyde biosynthetic process Added DEFINITION The formation from simpler components of formaldehyde (methanal, H2C=O), the simplest aldehyde.
2002-11-27 GO:0046294 formaldehyde catabolic process Added DEFINITION The breakdown into simpler components of formaldehyde (methanal, H2C=O), the simplest aldehyde.
2002-11-27 GO:0004327 formaldehyde dehydrogenase (glutathione) activity Added DEFINITION Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+.
2002-11-27 GO:0046292 formaldehyde metabolic process Added DEFINITION The chemical reactions and physical changes involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
2002-11-27 GO:0004328 formamidase activity Added DEFINITION Catalysis of the reaction: formamide + H2O = formate + ammonia.
2002-11-27 GO:0008862 formate acetyltransferase activating enzyme activity Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate acetyltransferase]-glycine = 5'-deoxyadenosine + methionine + flavodoxin + [formate acetyltransferase]-glycine-2-yl radical.
2002-11-27 GO:0015943 formate biosynthetic process Added DEFINITION The formation from simpler components of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
2002-11-27 GO:0008861 formate C-acetyltransferase activity Added DEFINITION Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.
2002-11-27 GO:0042183 formate catabolic process Added DEFINITION The breakdown into simpler components of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
2002-11-27 GO:0008863 formate dehydrogenase (NAD+) activity Added DEFINITION Catalysis of the reaction: formate + NAD+ = carbon dioxide + NADH + H+.
2002-11-27 GO:0009326 formate dehydrogenase complex Added DEFINITION An enzyme that catalyzes the dehydrogenation of formate to produce carbon dioxide.
2002-11-27 GO:0015942 formate metabolic process Added DEFINITION The chemical reactions and physical changes involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
2002-11-27 GO:0015724 formate transport Added DEFINITION Directed movement of formate into, outside, or within a cell.
2002-11-27 GO:0004329 formate-tetrahydrofolate ligase activity Added DEFINITION Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
2002-11-27 GO:0001704 formation of primary germ layer Added DEFINITION The formation of the ectoderm, mesoderm and endoderm during gastrulation.
2002-11-27 GO:0001732 formation of translation initiation complex Added DEFINITION Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methiionyl/formyl-methionyl-tRNA positioned at the P site.
2002-11-27 GO:0001677 formation of translation initiation ternary complex Added DEFINITION Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
2002-11-27 GO:0001731 formation of translation preinitiation complex Added DEFINITION The joining of the small ribosomal subunit, ternary complex, and mRNA.
2002-11-27 GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity Added DEFINITION Catalysis of the reaction: 5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH3.
2002-11-27 GO:0030407 formimidoyltransferase activity Added DEFINITION Catalysis of the transfer of a formimino group from 5-formimidoyltetrahydrofolate to an acceptor molecule such as an amino acid.
2002-11-27 GO:0018493 formylmethanofuran dehydrogenase activity Added DEFINITION Catalysis of the reaction: formylmethanofuran + H2O + acceptor = carbon dioxide + methanofuran + reduced acceptor.
2002-11-27 GO:0018884 carbazole metabolic process Added DEFINITION The chemical reactions and physical changes involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
2002-11-27 GO:0030246 carbohydrate binding Added DEFINITION Interacting selectively and stoichiometrically with any carbohydrate.
2002-11-27 GO:0016051 carbohydrate biosynthetic process Added DEFINITION The formation from simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
2002-11-27 GO:0016052 carbohydrate catabolic process Added DEFINITION The breakdown into simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
2002-11-27 GO:0009756 carbohydrate mediated signaling Added DEFINITION Signal transduction pathway mediated by the perception of carbohydrate.
2002-11-27 GO:0005975 carbohydrate metabolic process Added DEFINITION The chemical reactions and physical changes involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
2002-11-27 GO:0009758 carbohydrate utilization Added DEFINITION Series of processes that involve carbohydrate sensing, carbohydrate transportation and carbohydrate metabolism which lead to the utilization of carbohydrates.
2002-11-27 GO:0030634 carbon fixation by acetyl-CoA pathway Added DEFINITION A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide.
2002-11-27 GO:0018492 carbon-monoxide dehydrogenase (acceptor) activity Added DEFINITION Catalysis of the reaction: CO + H2O + acceptor = carbon dioxide + reduced acceptor.
2002-11-27 GO:0008805 carbon-monoxide oxygenase activity Added DEFINITION Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.
2002-11-27 GO:0019382 carbon tetrachloride catabolic process Added DEFINITION The breakdown into simpler components of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
2002-11-27 GO:0018885 carbon tetrachloride metabolic process Added DEFINITION The chemical reactions and physical changes involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
2002-11-27 GO:0004089 carbonate dehydratase activity Added DEFINITION Catalysis of the reaction: H2CO3 = carbon dioxide + H2O.
2002-11-27 GO:0004090 carbonyl reductase (NADPH) activity Added DEFINITION Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
2002-11-27 GO:0009702 L-arabinokinase activity Added DEFINITION Catalysis of the reaction: ATP + L-arabinose = ADP + beta-L-arabinose 1-phosphate.
2002-11-27 GO:0019572 L-arabinose catabolic process Added DEFINITION The breakdown into simpler components of L-arabinose, the levorotatory isomer of arabino-pentose.
2002-11-27 GO:0019570 L-arabinose catabolic process to 2-oxoglutarate Added DEFINITION The breakdown of L-arabinose into simpler components, including 2-oxoglutarate.
2002-11-27 GO:0019569 L-arabinose catabolic process to xylulose 5-phosphate Added DEFINITION The breakdown of L-arabinose into simpler components, including xylulose 5-phosphate.
2002-11-27 GO:0008733 L-arabinose isomerase activity Added DEFINITION Catalysis of the reaction: L-arabinose = L-ribulose.
2002-11-27 GO:0046373 L-arabinose metabolic process Added DEFINITION The chemical reactions and physical changes involving L-arabinose, the levorotatory isomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides and so on.
2002-11-27 GO:0008447 L-ascorbate oxidase activity Added DEFINITION Catalysis of the reaction: 2 L-ascorbate + O2 = 2 dehydroascorbate + 2 H2O.
2002-11-27 GO:0016688 L-ascorbate peroxidase activity Added DEFINITION Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.
2002-11-27 GO:0019853 L-ascorbic acid biosynthetic process Added DEFINITION The formation from simpler components of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
2002-11-27 GO:0019854 L-ascorbic acid catabolic process Added DEFINITION The breakdown into simpler components of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
2002-11-27 GO:0019852 L-ascorbic acid metabolic process Added DEFINITION The chemical reactions and physical changes involving L-ascorbic acid, a carbohydrate-like vitamin containing six carbon atoms per molecule. Widely distributed in fruit and vegetables.
2002-11-27 GO:0008734 L-aspartate oxidase activity Added DEFINITION Catalysis of the reaction: L-aspartate + H2O + O2 = oxaloacetate + ammonia + hydrogen peroxide.
2002-11-27 GO:0008735 carnitine dehydratase activity Added DEFINITION Catalysis of the reaction: L-carnitine = 4-(trimethylammonio)but-2-enoate + H2O.
2002-11-27 GO:0019448 L-cysteine catabolic process Added DEFINITION The breakdown into simpler components of L-cysteine, the levorotatory isomer of 2-amino-3-mercaptopropanoic acid.
2002-11-27 GO:0019449 L-cysteine catabolic process to hypotaurine Added DEFINITION The breakdown of L-cysteine into simpler components, including hypotaurine.
2002-11-27 GO:0019450 L-cysteine catabolic process to pyruvate Added DEFINITION The breakdown of L-cysteine into simpler components, including pyruvate.
2002-11-27 GO:0019451 L-cysteine catabolic process to pyruvate, using cysteine dioxygenase Added DEFINITION The breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).
2002-11-27 GO:0019452 L-cysteine catabolic process to taurine Added DEFINITION The breakdown of L-cysteine into simpler components, including taurine.
2002-11-27 GO:0019453 L-cysteine catabolic process via cystine Added DEFINITION The breakdown into simpler components of L-cysteine, via the intermediate cystine.
2002-11-27 GO:0019456 L-cysteine catabolic process via cystine, using cysteine transaminase Added DEFINITION The breakdown into simpler components, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3).
2002-11-27 GO:0019455 L-cysteine catabolic process via cystine, using cystine reductase Added DEFINITION The breakdown into simpler components, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6).
2002-11-27 GO:0019454 L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase Added DEFINITION The breakdown into simpler components, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4).
2002-11-27 GO:0046439 L-cysteine metabolic process Added DEFINITION The chemical reactions and physical changes involving L-cysteine, the levorotatory isomer of 2-amino-3-mercaptopropanoic acid.
2002-11-27 GO:0045438 delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity Added DEFINITION Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.
2002-11-27 GO:0006005 L-fucose biosynthetic process Added DEFINITION The formation from simpler components of L-fucose (6-deoxy-L-galactose).
2002-11-27 GO:0042355 L-fucose catabolic process Added DEFINITION The breakdown into simpler components of L-fucose (6-deoxy-Lgalactose).
2002-11-27 GO:0008736 L-fucose isomerase activity Added DEFINITION Catalysis of the reaction: L-fucose = L-fuculose.
2002-11-27 GO:0042354 L-fucose metabolic process Added DEFINITION The chemical reactions and physical changes involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus spp., and in the cell wall matrix of higher plants.
2002-11-27 GO:0008737 L-fuculokinase activity Added DEFINITION Catalysis of the reaction: ATP + L-fuculose = ADP + L-fuculose 1-phosphate.
2002-11-27 GO:0018035 C-terminal peptidyl-arginine amidation Added DEFINITION The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.
2002-11-27 GO:0018036 C-terminal peptidyl-asparagine amidation Added DEFINITION The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein.
2002-11-27 GO:0018037 C-terminal peptidyl-aspartic acid amidation Added DEFINITION The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.
2002-11-27 GO:0018038 C-terminal peptidyl-cysteine amidation Added DEFINITION The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.
2002-11-27 GO:0018040 C-terminal peptidyl-glutamic acid amidation Added DEFINITION The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.
2002-11-27 GO:0018039 C-terminal peptidyl-glutamine amidation Added DEFINITION The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.
2002-11-27 GO:0018041 C-terminal peptidyl-glycine amidation Added DEFINITION The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein.
2002-11-27 GO:0018042 C-terminal peptidyl-histidine amidation Added DEFINITION The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.
2002-11-27 GO:0018043 C-terminal peptidyl-isoleucine amidation Added DEFINITION The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.
2002-11-27 GO:0018044 C-terminal peptidyl-leucine amidation Added DEFINITION The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.
2002-11-27 GO:0018045 C-terminal peptidyl-lysine amidation Added DEFINITION The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.
2002-11-27 GO:0018046 C-terminal peptidyl-methionine amidation Added DEFINITION The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.
2002-11-27 GO:0018047 C-terminal peptidyl-phenylalanine amidation Added DEFINITION The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.
2002-11-27 GO:0018170 C-terminal peptidyl-polyglutamic acid amidation Added DEFINITION The formation of a C-terminal peptidyl-polyglutamic acid to form an N-L-glutamyl-poly-L-glutamic acid C-terminus.
2002-11-27 GO:0018048 C-terminal peptidyl-proline amidation Added DEFINITION The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.
2002-11-27 GO:0018049 C-terminal peptidyl-serine amidation Added DEFINITION The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.
2002-11-27 GO:0018050 C-terminal peptidyl-threonine amidation Added DEFINITION The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.
2002-11-27 GO:0018051 C-terminal peptidyl-tryptophan amidation Added DEFINITION The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.
2002-11-27 GO:0018052 C-terminal peptidyl-tyrosine amidation Added DEFINITION The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.
2002-11-27 GO:0018053 C-terminal peptidyl-valine amidation Added DEFINITION The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.
2002-11-27 GO:0019132 C-terminal processing peptidase activity Added DEFINITION The specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then catalyzes cleavage at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.
2002-11-27 GO:0006503 C-terminal protein farnesylation Added DEFINITION OBSOLETE. The covalent or non-covalent attachment of a farnesyl moiety to the carboxy terminus of a protein.
2002-11-27 GO:0006504 C-terminal protein geranylgeranylation Added DEFINITION OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl moiety to the carboxy terminus of a protein.
2002-11-27 GO:0006501 C-terminal protein lipidation Added DEFINITION The covalent or non-covalent attachment of a lipid moiety to the carboxy terminus of a protein.
2002-11-27 GO:0006502 C-terminal protein prenylation Added DEFINITION OBSOLETE. The covalent or non-covalent attachment of a prenyl moiety to the carboxy terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.
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