Proteomics Standards Initiative

1. Overall objective: What is the potential benefit of a common standard for protein-protein interaction data?
   Aim: Define use cases.
2. Overview of related/similar efforts.
3. Which data should be represented?
   1. Scope of the standard, granularity of data representation.
   2. data elements to be stored
      
   Aim: Outline data structure.
4. Which existing systems/controlled vocabularies/ontologies can be used, where do we need additional systems?
   Aim: List of existing components to be used, list of required components, ideally in order of urgency.
5. Representation of proposed data format: UML/XML?
6. Data exchange:
   1. no coordination,
   2. federated database with data exchange,
   3. federated database with common query interface?
   4. how to avoid redundancy?
   5. by flat/XML files
   6. Define availability levels:
      1. free
      2. free to end user (no redistribution)
      3. only "detail" access via tools
      4. private
   7. Data ownership, update policy.
7. Submission requirement by publishers: Current status.
8. Specialisation/coordination between databases for human curation?
9. Synchronised effort to create reference sets?
10. Quality control: accept only published data?