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Query examples - apoptosis, GO:0006915, tropomyosin, P06727.

Gene Ontology Annotation (UniProt-GOA) Database


The UniProt GO annotation program aims to provide high-quality Gene Ontology (GO) annotations to proteins in the UniProt Knowledgebase (UniProtKB). The assignment of GO terms to UniProt records is an integral part of UniProt biocuration. UniProt manual and electronic GO annotations are supplemented with manual annotations supplied by external collaborating GO Consortium groups, to ensure a comprehensive GO annotation dataset is supplied to users.

UniProt-GOA is a member of the GO Consortium.

For fast access to the Gene Ontology terms and annotations, please use our QuickGO browser.

Release cycle

All UniProt-GOA Gene Association Files are released approximately every four weeks and can be accessed from our Downloads page. We aim to coordinate our release with the UniProtKB releases. In addition, we release our human and chicken Gene Association Files every two weeks to enable the GO Consortium Reference Genome project to use our most up-to-date annotations for curation of orthologous species. These interim releases can be downloaded from our ftp site.

Latest UniProt-GOA news

All the latest news and information relating to UniProt-GOA.

Date UniProt-GOA News
16 May, 2012
1. New UniPathway2GO mapping provides an additional 113,285 GO annotations.

UniProt-GOA are pleased to announce that in collaboration with the Swiss Institute of Bioinformatics, INRIA (Rhone-Alpes) and Laboratoire d'Ecologie Alpine (Grenoble), we are able to offer an additional 113,285 GO annotations that describe the pathway(s) that 105,041 UniProtKB entries are involved in. 48% of these annotations apply a GO term that either uniquely describes a protein's involvement in a certain process, or supplies a more granular term than is supplied by other UniProt electronic annotation methods.

UniPathway is a manually curated resource of enzyme-catalyzed and spontaneous chemical reactions that provides a hierarchical representation of metabolic pathways. Descriptions of the pathway(s) that a particular protein is involved in are included in UniProtKB records. Further information on the UniPathway resource is available at
http://www.unipathway.org/obiwarehouse/unipathway.

So far, 425 UniPathway pathway terms have been manually mapped to GO terms. The mapping is available from:
http://www.grenoble.prabi.fr/dev/obiwarehouse/download/unipathway/public/unipathway2go.tsv

The reference cited for these annotations is GO_REF:0000041 (for further details see: http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000041)

2. Inclusion of multiple identifiers in the 'with/from' column of UniProt-GOA annotations

UniProt-GOA is able to include in this release those GO annotations that have applied more than one identifier in the 'with/from' annotation field (column 8 of the GAF2.0 format). This means that 12,317 annotations from external annotation groups are now more fully represented in the UniProt-GOA files, ensuring we are able to provide a more comprehensive set of GO annotations to users.
03 April, 2012
1. Annotation post-processing

As of this release, UniProt-GOA will be displaying some IEA annotations that have been subject to minor post-processing by UniProt to correct the assigned GO term. The focus of the changes is to ensure taxonomic correctness of annotated GO terms, using data supplied by the GO taxon rules:

ftp://ftp.geneontology.org/pub/go/quality_control/annotation_checks/taxon_checks/taxon_go_triggers.obo

Why is UniProt editing IEA annotations?

Edited IEA annotations are made by UniProt-GOA when the annotation originally supplied by the automatic annotation pipeline is incorrect for a UniProtKB protein and cannot be easily fixed by the annotation-contributing group without an unnecessarily high loss of correct annotations. This editing results in a conservatively-changed annotation, displaying an equivalent, correct GO term.

An example of this is the vaccinia virus DNA toposiomerase IB protein (UniProtKB:P68697), which has a prediction to 'GO:0005694; chromosome' from an electronic annotation source (InterPro). A slight change to this annotation prediction would lead to the correct term, 'GO:0044383; host chromosome', being supplied, which would be in accordance with the GO taxon rules, which require the term 'chromosome' only to be applied to cellular organisms (http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0005694#info=3)

Which annotation sets will be changed in this way?

UniProt-GOA will only carry out such changes to automatic annotation sets when it is the group primarily responsible for supplying the data for the proteome to the GO Consortium, and where the change to the annotation set at source is considered inappropriate. Such changes are made with the express agreement of the automatic annotation groups.

How to identify globally edited annotations?

All automatic annotations that are transformed by the UniProt-GOA processing will use a GO_REF reference that indicates to the user that such changes have occurred and which points users to this page: http://www.geneontology.org/cgi-bin/references.cgi. For example, UniProtKB:P68697, as described in the example above would be displayed with the accompanying GO_REF:0000042. Details of the annotation post-processing rules can be found at http://www.ebi.ac.uk/QuickGO/AnnotationPostProcessing.html.

2. Removal of automatic annotations that conflict with NOT-qualified manual GO annotations

In this release all IEA-evidenced annotations have been filtered to remove those which conflict with a NOT-qualified manual GO annotation for the same protein that has applied a GO identifier that is the same, or parent of the go identifier applied by the IEA method.

This filtering step has resulted in the removal of 8,000 incorrect IEA annotations from the UniProt file.
06 March, 2012
1. Change to the references applied by UniProtKB Keyword and UniProtKB Subcellular Location 2 GO annotations

As of this release, references supplied in annotations from two UniProtKB automatic annotation pipelines have changed.

Annotations created from mappings between GO and the UniProtKB keywords and UniProtKB Subcellular Location controlled vocabularies previously cited the GO reference GO_REF:0000004 and GO_REF:0000023, respectively.

However, terms from these UniProtKB controlled vocabularies are applied differently to UniProt Swiss-Prot and TrEMBL entries; UniProtKB terms are manually annotated to UniProtKB/Swiss-Prot entries, whereas UniProtKB/TrEMBL entries are annotated from data supplied by the underlying nucleic acid databases and/or by the UniProt automatic annotation program. As advised in our December 2011 release, we have now changed the cited references in the supplied GO annotations to highlight these differences.

From the current release onwards, the UniProt-GOA annotation set will use:
GO_REF:0000037 or GO_REF:0000038 instead of GO_REF:0000004 for UniProtKB keyword annotations
GO_REF:0000039 or GO_REF:0000040 instead of GO_REF:0000023 for UniProtKB Subcellular Location annotations

Further descriptions all of these references are available at: http://www.geneontology.org/cgi-bin/references.cgi

2. UniProt-GOA are delighted to announce that we now supply more than 120 million annotations to over 14 million proteins.

All annotations are available in the 106th release of the UniProt-GOA 'UniProt' file. The vast majority of the annotations (99%) are created by automatic annotation methods, including InterPro to GO and Swiss-Prot Keyword to GO mappings.
For more information on the automatic annotation methods that we incorporate, please see http://www.ebi.ac.uk/GOA/ElectronicAnnotationMethods.html.
For details on our manual annotation practices, please see http://www.ebi.ac.uk/GOA/ManualAnnotationEfforts.html.

UniProt-GOA would like to thank all of the contributing groups that have helped us reach this milestone. Links to our collaborating groups are displayed on our website, http://www.ebi.ac.uk/GOA.

10 January, 2012
Improvements to the HAMAP2GO annotation set

We are very pleased to announce that this UniProt-GOA release contains an improved set of HAMAP2GO annotations. The previous HAMAP2GO pipeline was unable to use the full complexity of the manually-curated UniProtKB HAMAP rules, however this has changed due to recent developments. The HAMAP source now predicts 3,458,519 GO annotations.
13 December, 2011
Scheduled change to the references applied by UniProtKB Keyword and UniProtKB Subcellular Location 2 GO annotations

We would like to alert users to an intended change in the references supplied in annotations from two UniProtKB automatic annotation pipelines.

Annotations created from mappings between GO and the UniProtKB keywords and UniProtKB Subcellular Location controlled vocabularies currently cite the GO reference GO_REF:0000004 and GO_REF:0000023, respectively.

However, terms from these UniProtKB controlled vocabularies are applied differently to UniProt Swiss-Prot and TrEMBL entries; UniProtKB terms are manually annotated to UniProtKB/Swiss-Prot entries, whereas UniProtKB/TrEMBL entries are annotated from data supplied by the underlying nucleic acid databases and/or by the UniProt automatic annotation program. We intend to change the cited references in the supplied GO annotations to highlight these differences.

Therefore, from the February 2012 release onwards, the UniProt-GOA annotation set will use:
GO_REF:0000037 or GO_REF:0000038 instead of GO_REF:0000004 for UniProtKB keyword annotations
GO_REF:0000039 or GO_REF:0000040 instead of GO_REF:0000023 for UniProtKB Subcellular Location annotations

Further descriptions all of these references are available at: http://www.geneontology.org/cgi-bin/references.cgi
20 September, 2011
UniProt-GOA are delighted to announce that we now supply more than 100 million annotations to over 11 million proteins.

All annotations are available in the 100th release of the UniProt-GOA 'UniProt' file. The vast majority of the annotations (99%) are created by automatic annotation methods, including InterPro to GO and Swiss-Prot Keyword to GO mappings.
For more information on the automatic annotation methods that we incorporate, please see http://www.ebi.ac.uk/GOA/ElectronicAnnotationMethods.html.
For details on our manual annotation practices, please see http://www.ebi.ac.uk/GOA/ManualAnnotationEfforts.html.

UniProt-GOA would like to thank all of the contributing groups that have helped us reach this milestone. Links to our collaborating groups are displayed on our website, http://www.ebi.ac.uk/GOA.
24 August, 2011

In this release, the UniProt GO annotation files contain a greatly reduced number of protein binding GO annotations from the IntAct database. A subset of presumed reliable interactions is now extracted from the IntAct dataset with export determined using a simple scoring system developed by IntAct, coupled to a score threshold that has been deliberately chosen to exclude interactions supported by only one experimental observation. Further details of how interactions are scored can be found at the IntAct website (http://www.ebi.ac.uk/intact/pages/faq/faq.xhtml#4). This simple score-based filter is used in combination with a set of defined rules that excludes certain types of data, such as interactions that have been inferred but not experimentally proven.

UniProt-GOA are pleased to announce the inclusion in their database of electronic GO annotations created by EnsemblPlants/Gramene. The annotations are created by projection of GO annotations from Arabidopsis thaliana or Oryza sativa proteins onto proteins from one or more target species based on gene orthology obtained from Ensembl Compara. This first release contains almost 230,000 annotations to over 50,000 proteins covering 16 taxonomies including; poplar, maize, sorghum, grape and Physcomitrella. We hope this will be a valuable resource for the non-model plant species community. The annotations can be viewed and downloaded from the QuickGO browser here.

28 July, 2011
1. With the imminent closure of the International Protein Index (IPI), we would like to alert users of the Human, Mouse, Rat, Zebrafish, Chicken and Cow UniProt GO annotation files (files named: gene_association.goa_[species], e.g., gene_association.goa_human) that our July GO annotation release now uses UniProt Complete Proteome sets to determine the protein composition of these files. Further information on UniProt Complete Proteome sets is available here.

This change has had a dramatic affect on the gene_association.goa_human file, which has increase in annotation count by 43.7% , as the file now includes GO annotations both to reviewed (Swiss-Prot) and unreviewed (TrEMBL) UniProtKB accessions. Any user wishing to only identify the reviewed (Swiss-Prot) UniProt protein annotation subset will be able continue to do so using the information supplied in the gp_information.goa_uniprot file, which can be found here.
Alternatively, users can download the reviewed UniProtKB human GO annotation set from the UniProt QuickGO browser using this link.

Users of the Zebrafish species-specific gene association file will, however, notice a decrease in annotations this release, caused by major changes to the Ensembl Zebrafish ENSP identifier set that has resulted in a decreased set of electronic GO annotations obtained from the application of Ensembl Compara orthology data, as well as a decrease in ZFIN manual GO annotations caused by differences in the set of UniProtKB accessions selected for the Zebrafish UniProtKB proteome set and those currently mapped to ZFIN identifiers.

2. An additional restriction on the HAMAP2GO electronic GO annotation pipeline, filtering out all HAMAP2GO predictions for proteins in the Metazoan kingdom, has enabled us to remove incorrect GO annotation predictions for a number of species.

3. Species-specific UniProt GO annotation gene association files that include a filtering step to remove redundant electronic GO annotation predictions are now available from the GOA ftp site for the UniProt Complete Proteome sets of Dictyostellium discoideum (gene_association.goa_dicty.gz), Canis familiaris (gene_association.goa_dog.gz), Drosophila melanogaster (gene_association.goa_fly.gz), Caenorhabditis elegans (gene_association.goa_worm.gz), Saccharomyces cerevisiae (gene_association.goa_yeast) and Sus scrofa (gene_association.goa_pig.gz).


Latest UniProt-GOA releases


Date UniProt-GOA Release
16 May, 2012
GOA UniProt 108 Released
Version 108 UniProt GO annotation has been released.

GOA Human 110 Released
Version 110 of human GOA has been released.

GOA Mouse 96 Released
Version 96 of mouse GOA has been released.

GOA Rat 96 Released
Version 96 of rat GOA has been released.

GOA Arabidopsis 83 Released
Version 83 of arabidopsis GOA has been released.

GOA Zebrafish 83 Released
Version 83 of zebrafish GOA has been released.

GOA Chicken 80 Released
Version 80 of chicken GOA has been released.

GOA Cow 73 Released
Version 73 of cow GOA has been released.

GOA Dicty 11 Released
Version 11 of dicty GOA has been released.

GOA Dog 11 Released
Version 11 of dog GOA has been released.

GOA Pig 11 Released
Version 11 of pig GOA has been released.

GOA Fly 11 Released
Version 11 of fly GOA has been released.

GOA Worm 11 Released
Version 11 of worm GOA has been released.

GOA Yeast 11 Released
Version 11 of yeast GOA has been released.

GOA PDB 97 Released

GOA Proteome Sets 85 Released
We are pleased to introduce GO annotation to 2994 proteome sets in this release.  For information please follow this link.
03 April, 2012
GOA UniProt 107 Released
Version 107 UniProt GO annotation has been released.

GOA Human 109 Released
Version 109 of human GOA has been released.

GOA Mouse 95 Released
Version 95 of mouse GOA has been released.

GOA Rat 95 Released
Version 95 of rat GOA has been released.

GOA Arabidopsis 82 Released
Version 82 of arabidopsis GOA has been released.

GOA Zebrafish 82 Released
Version 82 of zebrafish GOA has been released.

GOA Chicken 79 Released
Version 79 of chicken GOA has been released.

GOA Cow 72 Released
Version 72 of cow GOA has been released.

GOA Dicty 10 Released
Version 10 of dicty GOA has been released.

GOA Dog 10 Released
Version 10 of dog GOA has been released.

GOA Pig 10 Released
Version 10 of pig GOA has been released.

GOA Fly 10 Released
Version 10 of fly GOA has been released.

GOA Worm 10 Released
Version 10 of worm GOA has been released.

GOA Yeast 10 Released
Version 10 of yeast GOA has been released.

GOA PDB 96 Released

GOA Proteome Sets 84 Released
We are pleased to introduce GO annotation to 2968 proteome sets in this release.  For information please follow this link.
06 March, 2012
GOA UniProt 106 Released
Version 106 UniProt GO annotation has been released.

GOA Human 108 Released
Version 108 of human GOA has been released.

GOA Mouse 94 Released
Version 94 of mouse GOA has been released.

GOA Rat 94 Released
Version 94 of rat GOA has been released.

GOA Arabidopsis 81 Released
Version 81 of arabidopsis GOA has been released.

GOA Zebrafish 81 Released
Version 81 of zebrafish GOA has been released.

GOA Chicken 78 Released
Version 78 of chicken GOA has been released.

GOA Cow 71 Released
Version 71 of cow GOA has been released.

GOA Dicty 9 Released
Version 9 of dicty GOA has been released.

GOA Dog 9 Released
Version 9 of dog GOA has been released.

GOA Pig 9 Released
Version 9 of pig GOA has been released.

GOA Fly 9 Released
Version 9 of fly GOA has been released.

GOA Worm 9 Released
Version 9 of worm GOA has been released.

GOA Yeast 9 Released
Version 9 of yeast GOA has been released.

GOA PDB 95 Released

GOA Proteome Sets 83 Released
We are pleased to introduce GO annotation to 2956 proteome sets in this release.  For information please follow this link.
08 February, 2012
GOA UniProt 105 Released
Version 105 UniProt GO annotation has been released.

GOA Human 107 Released
Version 107 of human GOA has been released.

GOA Mouse 93 Released
Version 93 of mouse GOA has been released.

GOA Rat 93 Released
Version 93 of rat GOA has been released.

GOA Arabidopsis 80 Released
Version 80 of arabidopsis GOA has been released.

GOA Zebrafish 80 Released
Version 80 of zebrafish GOA has been released.

GOA Chicken 77 Released
Version 77 of chicken GOA has been released.

GOA Cow 70 Released
Version 70 of cow GOA has been released.

GOA Dicty 8 Released
Version 8 of dicty GOA has been released.

GOA Dog 8 Released
Version 8 of dog GOA has been released.

GOA Pig 8 Released
Version 8 of pig GOA has been released.

GOA Fly 8 Released
Version 8 of fly GOA has been released.

GOA Worm 8 Released
Version 8 of worm GOA has been released.

GOA Yeast 8 Released
Version 8 of yeast GOA has been released.

GOA PDB 94 Released

GOA Proteome Sets 82 Released
We are pleased to introduce GO annotation to 2912 proteome sets in this release.  For information please follow this link.
10 January, 2012
GOA UniProt 104 Released
Version 104 UniProt GO annotation has been released.

GOA Human 106 Released
Version 106 of human GOA has been released.

GOA Mouse 92 Released
Version 92 of mouse GOA has been released.

GOA Rat 92 Released
Version 92 of rat GOA has been released.

GOA Arabidopsis 79 Released
Version 79 of arabidopsis GOA has been released.

GOA Zebrafish 79 Released
Version 79 of zebrafish GOA has been released.

GOA Chicken 76 Released
Version 76 of chicken GOA has been released.

GOA Cow 69 Released
Version 69 of cow GOA has been released.

GOA Dicty 7 Released
Version 7 of dicty GOA has been released.

GOA Dog 7 Released
Version 7 of dog GOA has been released.

GOA Pig 7 Released
Version 7 of pig GOA has been released.

GOA Fly 7 Released
Version 7 of fly GOA has been released.

GOA Worm 7 Released
Version 7 of worm GOA has been released.

GOA Yeast 7 Released
Version 7 of yeast GOA has been released.

GOA PDB 93 Released

GOA Proteome Sets 81 Released
We are pleased to introduce GO annotation to 2884 proteome sets in this release.  For information please follow this link.
13 December, 2011
GOA UniProt 103 Released
Version 103 UniProt GO annotation has been released.

GOA Human 105 Released
Version 105 of human GOA has been released.

GOA Mouse 91 Released
Version 91 of mouse GOA has been released.

GOA Rat 91 Released
Version 91 of rat GOA has been released.

GOA Arabidopsis 78 Released
Version 78 of arabidopsis GOA has been released.

GOA Zebrafish 78 Released
Version 78 of zebrafish GOA has been released.

GOA Chicken 75 Released
Version 75 of chicken GOA has been released.

GOA Cow 68 Released
Version 68 of cow GOA has been released.

GOA Dicty 6 Released
Version 6 of dicty GOA has been released.

GOA Dog 6 Released
Version 6 of dog GOA has been released.

GOA Pig 6 Released
Version 6 of pig GOA has been released.

GOA Fly 6 Released
Version 6 of fly GOA has been released.

GOA Worm 6 Released
Version 6 of worm GOA has been released.

GOA Yeast 6 Released
Version 6 of yeast GOA has been released.

GOA PDB 92 Released

GOA Proteome Sets 80 Released
We are pleased to introduce GO annotation to 1872 proteome sets in this release.  For information please follow this link.
15 November, 2011
GOA UniProt 102 Released
Version 102 UniProt GO annotation has been released.

GOA Human 104 Released
Version 104 of human GOA has been released.

GOA Mouse 90 Released
Version 90 of mouse GOA has been released.

GOA Rat 90 Released
Version 90 of rat GOA has been released.

GOA Arabidopsis 77 Released
Version 77 of arabidopsis GOA has been released.

GOA Zebrafish 77 Released
Version 77 of zebrafish GOA has been released.

GOA Chicken 74 Released
Version 74 of chicken GOA has been released.

GOA Cow 67 Released
Version 67 of cow GOA has been released.

GOA Dicty 5 Released
Version 5 of dicty GOA has been released.

GOA Dog 5 Released
Version 5 of dog GOA has been released.

GOA Pig 5 Released
Version 5 of pig GOA has been released.

GOA Fly 5 Released
Version 5 of fly GOA has been released.

GOA Worm 5 Released
Version 5 of worm GOA has been released.

GOA Yeast 5 Released
Version 5 of yeast GOA has been released.

GOA PDB 91 Released

GOA Proteome Sets 79 Released
We are pleased to introduce GO annotation to 1873 proteome sets in this release.  For information please follow this link.
18 October, 2011
GOA UniProt 101 Released
Version 101 UniProt GO annotation has been released.

GOA Human 103 Released
Version 103 of human GOA has been released.

GOA Mouse 89 Released
Version 89 of mouse GOA has been released.

GOA Rat 89 Released
Version 89 of rat GOA has been released.

GOA Arabidopsis 76 Released
Version 76 of arabidopsis GOA has been released.

GOA Zebrafish 76 Released
Version 76 of zebrafish GOA has been released.

GOA Chicken 73 Released
Version 73 of chicken GOA has been released.

GOA Cow 66 Released
Version 66 of cow GOA has been released.

GOA Dicty 4 Released
Version 4 of dicty GOA has been released.

GOA Dog 4 Released
Version 4 of dog GOA has been released.

GOA Pig 4 Released
Version 4 of pig GOA has been released.

GOA Fly 4 Released
Version 4 of fly GOA has been released.

GOA Worm 4 Released
Version 4 of worm GOA has been released.

GOA Yeast 4 Released
Version 4 of yeast GOA has been released.

GOA PDB 90 Released

GOA Proteome Sets 78 Released
We are pleased to introduce GO annotation to 1846 proteome sets in this release.  For information please follow this link.
20 September, 2011
GOA UniProt 100 Released
Version 100 UniProt GO annotation has been released.

GOA Human 102 Released
Version 102 of human GOA has been released.

GOA Mouse 88 Released
Version 88 of mouse GOA has been released.

GOA Rat 88 Released
Version 88 of rat GOA has been released.

GOA Arabidopsis 75 Released
Version 75 of arabidopsis GOA has been released.

GOA Zebrafish 75 Released
Version 75 of zebrafish GOA has been released.

GOA Chicken 72 Released
Version 72 of chicken GOA has been released.

GOA Cow 65 Released
Version 65 of cow GOA has been released.

GOA Dicty 3 Released
Version 3 of dicty GOA has been released.

GOA Dog 3 Released
Version 3 of dog GOA has been released.

GOA Pig 3 Released
Version 3 of pig GOA has been released.

GOA Fly 3 Released
Version 3 of fly GOA has been released.

GOA Worm 3 Released
Version 3 of worm GOA has been released.

GOA Yeast 3 Released
Version 3 of yeast GOA has been released.

GOA PDB 89 Released

GOA Proteome Sets 77 Released
We are pleased to introduce GO annotation to 1764 proteome sets in this release.  For information please follow this link.
24 August, 2011
GOA UniProt 99 Released
Version 99 UniProt GO annotation has been released.

GOA Human 101 Released
Version 101 of human GOA has been released.

GOA Mouse 87 Released
Version 87 of mouse GOA has been released.

GOA Rat 87 Released
Version 87 of rat GOA has been released.

GOA Arabidopsis 74 Released
Version 74 of arabidopsis GOA has been released.

GOA Zebrafish 74 Released
Version 74 of zebrafish GOA has been released.

GOA Chicken 71 Released
Version 71 of chicken GOA has been released.

GOA Cow 64 Released
Version 64 of cow GOA has been released.

GOA Dicty 2 Released
Version 2 of dicty GOA has been released.

GOA Dog 2 Released
Version 2 of dog GOA has been released.

GOA Pig 2 Released
Version 2 of pig GOA has been released.

GOA Fly 2 Released
Version 2 of fly GOA has been released.

GOA Worm 2 Released
Version 2 of worm GOA has been released.

GOA Yeast 2 Released
Version 2 of yeast GOA has been released.

GOA PDB 88 Released

GOA Proteome Sets 76 Released
We are pleased to introduce GO annotation to 1759 proteome sets in this release.  For information please follow this link.
28 July, 2011
GOA UniProt 98 Released
Version 98 UniProt GO annotation has been released.

GOA Human 100 Released
Version 100 of human GOA has been released.

GOA Mouse 86 Released
Version 86 of mouse GOA has been released.

GOA Rat 86 Released
Version 86 of rat GOA has been released.

GOA Arabidopsis 73 Released
Version 73 of arabidopsis GOA has been released.

GOA Zebrafish 73 Released
Version 73 of zebrafish GOA has been released.

GOA Chicken 70 Released
Version 70 of chicken GOA has been released.

GOA Cow 63 Released
Version 63 of cow GOA has been released.

GOA Dicty 1 Released
Version 1 of dicty GOA has been released.

GOA Dog 1 Released
Version 1 of dog GOA has been released.

GOA Pig 1 Released
Version 1 of pig GOA has been released.

GOA Fly 1 Released
Version 1 of fly GOA has been released.

GOA Worm 1 Released
Version 1 of worm GOA has been released.

GOA Yeast 1 Released
Version 1 of yeast GOA has been released.

GOA PDB 87 Released

GOA Proteome Sets 75 Released
We are pleased to introduce GO annotation to 1707 proteome sets in this release.  For information please follow this link.

Funding


Current Funding:

  • EMBL

  • NIH grant number R01HG02273-02: Gene Ontology Consortium

  • British Heart Foundation grant (SP:07/007/23671) 'The Integration of the knowledge if genes involved in heart development and cardiovascular processes from biomedical research, using standardised Gene Ontology'

  • Kidney Research UK Project Grant RP26/2008 - 'Integration of knowledge of genes involved in renal processes from biomedical research using the Gene Ontology'.

  • NIH grant number 2U01HG02712-04: UniProtKB Consortium
Previous Funding:
  • European Union grant number QLRI-CT-2001000015: TEMBLOR - The European Molecular Biology Linked Original Resources

  • European Union grant number QLRT-CT-2001-00981; BioBabel- Enhanced Interoperability of Biological Databases by Standardisation of Biochemical Terminology and Introduction of a Shared Ontology

  • BBSRC Tools and Resources Fund grant (BB/E023541/1) 'Further development of the QuickGO web interface for browsing and retrieving Gene Ontology Annotation Data'.





UniProt-GOA is also grateful to the developers and curators from the GO Consortium and GO associate member databases.

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