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EBIDatabasesBiological OntologiesGOA
 

Query examples - apoptosis, GO:0006915, tropomyosin, P06727.

Gene Ontology Annotation (GOA) Database


The GOA project aims to provide high-quality Gene Ontology (GO) annotations to proteins in the UniProt Knowledgebase (UniProtKB) and International Protein Index (IPI) and is a central dataset for other major multi-species databases; such as Ensembl and NCBI.

GOA has been a member of the GO Consortium since 2001, and is responsible for the integration and release of GO annotations to the human, chicken and cow proteomes. Because of the multi-species nature of the UniProtKB, GOA also assists in the curation of another 200,000 species. This involves electronic annotation and the integration of high-quality manual GO annotation from all GO Consortium model organism groups and specialist groups. This effort ensures that the GOA dataset remain a key reference and a comprehensive source of GO annotation for all species.

For fast access to the Gene Ontology terms and annotations, please use our QuickGO browser.

Latest GOA news

All the latest news and information relating to GOA.

Date GOA News
08 October, 2009
 Please note that the contents of the gene_association.goa_pdb file has changed as of this release, as GOA is no longer able to provide annotations to specific PDB chains. In future annotations in this file will only associate PDB entries with GO terms. As an example, an annotation line in the PDB file has changed from:

PDB 102M_A q_A GO:0005506 GOA:interpro IEA InterPro:IPR000971 F protein_structure taxon:9755 20090629 UniProtKB
to:
PDB 102M 102M GO:0005506 GOA:interpro IEA InterPro:IPR000971 F protein_structure taxon:9755 20091001 UniProtKB

Please contact us if this change is of concern.


Latest GOA releases


Date GOA Release
08 October, 2009
 GOA UniProt 76 Released
Version 76 UniProt GO annotation has been released.

GOA Human 78 Released
Version 78 of human GOA has been released.

GOA Mouse 64 Released
Version 64 of mouse GOA has been released.

GOA Rat 64 Released
Version 64 of rat GOA has been released.

GOA Arabidopsis 51 Released
Version 51 of arabidopsis GOA has been released.

GOA Zebrafish 51 Released
Version 51 of zebrafish GOA has been released.

GOA Chicken 48 Released
Version 48 of chicken GOA has been released.

GOA Cow 41 Released
Version 41 of cow GOA has been released.

GOA PDB 65 Released

GOA Proteome Sets 53 Released
 We are pleased to introduce GO annotation to 1739 proteome sets in this release.  For information please follow this link.

Funding


Current Funding:
  • EMBL

  • NIH grant number R01HG02273-02: Gene Ontology Consortium

  • British Heart Foundation grant (SP:07/007/23671) 'The Integration of the knowledge if genes involved in heart development and cardiovascular processes from biomedical research, using standardised Gene Ontology'

  • Kidney Research UK Project Grant RP26/2008 - 'Integration of knowledge of genes involved in renal processes from biomedical research using the Gene Ontology'.

  • NIH grant number 2U01HG02712-04: UniProtKB Consortium
Previous Funding:
  • European Union grant number QLRI-CT-2001000015: TEMBLOR - The European Molecular Biology Linked Original Resources

  • European Union grant number QLRT-CT-2001-00981; BioBabel- Enhanced Interoperability of Biological Databases by Standardisation of Biochemical Terminology and Introduction of a Shared Ontology

  • BBSRC Tools and Resources Fund grant (BB/E023541/1) 'Further development of the QuickGO web interface for browsing and retrieving Gene Ontology Annotation Data'.





GOA is also grateful to the developers and curators from the GO Consortium and GO associate member databases.

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