Gene Ontology Annotation (UniProt-GOA) Database
The UniProt GO annotation program aims to provide high-quality Gene Ontology (GO) annotations to proteins in the UniProt Knowledgebase (UniProtKB).
The assignment of GO terms to UniProt records is an integral part of UniProt biocuration. UniProt manual and electronic GO annotations are supplemented with manual annotations supplied by external collaborating GO Consortium groups, to ensure a comprehensive GO annotation dataset is supplied to users.
For fast access to the Gene Ontology terms and annotations, please use our QuickGO browser.
All UniProt-GOA Gene Association Files are released approximately every four weeks and can be accessed from our Downloads page. We aim to coordinate our release with the UniProtKB releases. In addition, we release our human and chicken Gene Association Files every two weeks to enable the GO Consortium Reference Genome project to use our most up-to-date annotations for curation of orthologous species. These interim releases can be downloaded from our ftp site.
Latest UniProt-GOA news
All the latest news and information relating to UniProt-GOA.
|04 July, 2017|| We are pleased to announce that the latest set of UniProt-GOA release files are available from ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/
- NIH-NHGRI [1U41HG006104-03]: UniProtKB Consortium
- National Human Genome Research Institute (NHGRI) [5P41HG002273-09]: Gene Ontology Consortium
- British Heart Foundation [RG/13/5/30112]: The integration of biomedical research, describing the biological processes relevant to cardiovascular processes, into Gene Ontology, microRNA and protein interaction databases
- Parkinson’s UK [G-1307]: The integration of biomedical research, describing the biological processes relevant to Parkinson’s disease, into the Gene Ontology database
- British Heart Foundation grant [SP:07/007/23671] 'The Integration of the knowledge if genes involved in heart development and cardiovascular processes from biomedical research, using
standardised Gene Ontology'
- Kidney Research UK Project Grant RP26/2008 - 'Integration of knowledge of genes involved in renal processes from biomedical research using the Gene Ontology'.
- European Union grant number QLRI-CT-2001000015: TEMBLOR - The European Molecular Biology Linked Original Resources
- European Union grant number QLRT-CT-2001-00981; BioBabel- Enhanced Interoperability of Biological Databases by Standardisation of Biochemical Terminology and Introduction of a Shared Ontology
- BBSRC Tools and Resources Fund grant (BB/E023541/1) 'Further development of the QuickGO web interface for browsing and retrieving Gene Ontology Annotation Data'.
UniProt-GOA is also grateful to the developers and curators from the GO Consortium and GO associate member databases.
- Searching UniProt-GOA
- Annotation Methods
- Annotation Tutorial
- Manual Annotation Efforts
- Electronic Annotation Methods
- Contribute Data
- News Archive
- Release Archive