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2Can Support Portal - Genome Browsing
Introduction
There are 2 main genome browsers, the Ensembl genome browser in the UK and the UCSC Genome Bioinformatics genome browser in the USA. |
UCSC Genome Bioinformatics
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This site contains working drafts for the human, mouse, and rat genomes. |
Ensembl
Ensembl presents up-to-date sequence data and the best possible automatic annotation for eukaryotic genomes. Among the 40 or so species now available are human, mouse, rat, pufferfish, mosquito and lizard.
Ensembl provides:
- Easy access to sequence data
- For known genes, predicted structure and location in the genome sequence
- Prediction of novel genes, all with supporting evidence
- Annotation of other features of the genome
- Targeted connections to other genome resources worldwide
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Ensembl for Schools!
The Human Genome
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To know and understand ourselves: 5 1/2 billion people on earth with
less than 100,000 proteins each with a corresponding set of genes. Understanding
how these are organised and work, as well as elucidating the differences should
lead to the overall improvement in the quality of life for all. |
Browse a Human Chromosome
Clicking on any chromosome will take you to the corresponding chromosome map page, which will allow you to select a region to view by clicking on a band, specify a chromosome region using marker names, jump to a view of synthetic regions in other species and see basic statistics on that chromosome.
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Other Species
The Mouse
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The Mouse genome dictionary identifies 1200 new genes in the human book of life, a significant number of which are likely to be involved in cancers and other diseases. These findings will allow researchers to home in more rapidly on genes in order to better diagnose and treat many human diseases. |
The Rat
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The wide array of rat strains provides an extraordinary tool for studying the genetic basis of disease. Extensive work involving the rat has been done on hypertension, diabetes, renal failure, autoimmunity, alcohol preference and neurobiology. |
The Zebrafish
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The Zebrafish is also very important as it has been the organism of choice to study early vertebrate embryonic development and has provided scientists with a deep understanding of how our bones, organs and central nervous system develops from the time of conception. |
The Pufferfish
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By comparing the human and Fugu sequences, common functional elements such as genes and regulatory sequences can be recognised as having been preserved in the two genomes over the course of the 450 million years since the species diverged from their common ancestor. |
The Mosquito
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Malaria kills 1 child every 30 seconds mostly around the tropical regions of the planet. It is the number one killer and affects half of the world population. The mosquito (Anopheles gambiae) is not responsible for the disease itself. |
Educational Resources
A list of educational resources provided by ensembl are shown below.
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Contact
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The purpose of these kits is to give you interesting and fun ways to show
students how biological research promises to have a huge effect on all of
our lives in the very near future, particularly in the field of medicine. The
activities here are not only for biology and science teachers; many of them
can be done in other classes as well. Contests & Prizes are also available.