Bacteria Genomes - BORTEDELLA BRONCHISEPTICA

Bordetella bronchiseptica is a Gram-negative beta-proteobacteria that colonizes the respiratory tracts of mammals and are closely related to Bordetella pertussis and Bordetella parapertussis.

Bordetella bronchiseptica appears to be a primary respiratory pathogen in cats, causes tracheobronchitis (kennel cough) in dogs which is marked by an acute onset of a harsh, "honking" cough, often elicited by tracheal palpation, atrophic rhinitis in pigs and "snuffles" in rabbits (this is also related to Pasteurella infection).

Bordetella bronchiseptica is an uncommon infection in humans (since 1911, 65 cases have been reported) that generally produce a relatively non-threatening, "whooping cough" like syndrome in immunocompetent individuals. However, B. bronchiseptica has been associated with endocarditis, peritonitis, meningitis and wound infections. In some cases, a direct connection to animals is obvious.

Bordetella bronchiseptica is being isolated increasingly from immunocompromised hosts with respiratory tract infections ranging from sinusitis to pneumonia/pleuritis.

References:

Nat. Genet. 35(1):32-40. 2004 DOI:10.1038/Ng1227-10.1038/Ng1227
http://www.genomenewsnetwork.org/sequenced_genomes/genome_guide_p1.shtml
http://www.sanger.ac.uk/Projects/B_pertussis/
http://www.vetmed.wisc.edu/pbs/zoonoses/Bordetella/bordetellaindex.html