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Protein Databases
 Primary protein sequence databases - UniProtKB/Swiss-Prot
UniProt (Universal Protein Resource) is the world's most comprehensive
catalogue of information on proteins. It is a central repository of protein
sequence and function created by joining the information contained in
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and PIR.
UniProt is comprised of three components, each optimised for different uses.
The UniProt Knowledgebase (UniProt) is the central access point for
extensive curated protein information, including function, classification,
and cross-reference. The UniProt Reference Clusters (UniRef) databases
combine closely related sequences into a single record to speed searches.
The UniProt Archive (UniParc) is a comprehensive repository, reflecting the
history of all protein sequences.
Click here to see a UniProtKB/Swiss-Prot example entry
UniProt contains data that originates
from a wide variety of organisms from more than 6,000 different species. Half of the entries come from about 20 organisms, which are the target of
many biological studies (ranked by number of entries):
- Homo sapiens
- Saccharomyces cerevisiae
- Escherichia coli
- Mus musculus
- Rattus norvegicus
- Bacillus subtilis
- Caenorhabditis elegans
- Haemophilus influenzae
- Schizosaccharomyces pombe
- Methanococcus jannaschii
- Bos taurus
- Drosophila melanogaster
- Mycobacterium tuberculosis
- Gallus gallus
- Arabidopsis thaliana
- Salmonella typhimurium
- Xenopus laevis
- Synechocystis sp. (strain PCC 6803)
- Sus scrofa
- Oryctolagus cuniculus
More detailed information relating to UniProt can be found in the UniProt user manual, it contains a comprehensive description of the database and it's entiries.
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